Schistosomiasis

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21 Substances Researched for Schistosomiasis
NameACCKFocus
Wormwood110Locked
Garlic36Locked
Nigella sativa (aka Black Seed)24Locked
Paeoniflorin24Locked
Curcumin23Locked
Agaricus Blazei12Locked
Allicin12Locked
Artichoke12Locked
Asafoetida12Locked
Baccharis trimera12Locked
Genistein12Locked
Ginger12Locked
Myrrh12Locked
Piperlongumine 12Locked
Probiotics12Locked
Yoghurt12Locked
Camu Camu 11Locked
Licorice11Locked
Pumpkin Seed Oil/Meal11Locked
Tansy11Locked
Tongkat Ali11Locked

View the Evidence:
38 Abstracts with Schistosomiasis Research

[+]

Association between serum vitamin D level and immune imbalance in advanced schistosomiasis patients with liver fibrosis.Feb 03, 2021

Pubmed Data : Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2021 Feb 4 ;33(1):22-27. PMID: 33660470
Article Published Date : Feb 03, 2021
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Liver Cirrhosis, Liver Fibrosis, Schistosomiasis
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective, Immunomodulatory
[+]

Effect of Artemisia annua and Artemisia afra tea infusions on schistosomiasis in a large clinical trial.Nov 30, 2018

Pubmed Data : Phytomedicine. 2018 Dec 1 ;51:233-240. Epub 2018 Oct 10. PMID: 30466622
Article Published Date : Nov 30, 2018
Study Type : Human Study
Additional Links
Substances : Wormwood
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

Brazilian green propolis reduces worm burden and hepatic granuloma formation in a Schistosoma mansoni experimental murine model.Jan 31, 2022

Pubmed Data : Parasitol Res. 2022 Feb ;121(2):775-780. Epub 2022 Jan 20. PMID: 35048211
Article Published Date : Jan 31, 2022
Study Type : Animal Study
Additional Links
Substances : Bee Propolis
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

Antiparasitic activity of piplartine in a mouse model of schistosomiasis.Jan 17, 2020

Pubmed Data : Acta Trop. 2020 Jan 18:105350. Epub 2020 Jan 18. PMID: 31962096
Article Published Date : Jan 17, 2020
Study Type : Animal Study
Additional Links
Substances : Piperlongumine
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

Antischistosomal and anti-inflammatory activity of garlic and allicin compared with that of praziquantel in vivo.Apr 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 Apr 27 ;18(1):135. Epub 2018 Apr 27. PMID: 29703259
Article Published Date : Apr 26, 2018
Study Type : Animal Study
Additional Links
Substances : Allicin, Garlic
Diseases : Schistosomiasis
Pharmacological Actions : Anti-Inflammatory Agents, Schistosomicides
Additional Keywords : Natural Substances Versus Drugs
[+]

Antischistosomal effects of Ficus carica leaves extract and/or PZQ on Schistosoma mansoni infected mice.Feb 28, 2022

Pubmed Data : J Parasit Dis. 2022 Mar ;46(1):87-102. Epub 2021 Jul 29. PMID: 35299912
Article Published Date : Feb 28, 2022
Study Type : Animal Study
Additional Links
Substances : Fig
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

Artichoke leaf extract protects liver of Schistosoma mansoni infected mice through modulation of hepatic stellate cells recruitment.Jun 30, 2017

Pubmed Data : Exp Parasitol. 2017 Jul ;178:51-59. Epub 2017 May 25. PMID: 28552793
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Artichoke
Diseases : Liver Cirrhosis, Schistosomiasis
Pharmacological Actions : Hepatoprotective
Additional Keywords : Plant Extracts
[+]

B. trimera exhibits major schistosomicidal effects in vivo against immature and adult worms of S. mansoni.Mar 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Parasitol. 2014 Apr ;139:63-72. Epub 2014 Mar 3. PMID: 24602876
Article Published Date : Mar 31, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Baccharis trimera
Diseases : Flukes, Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Plant Extracts
[+]

Bioactivity of Trigonella foenum oil on immunological and biochemical response of Schistosoma mansoni.Dec 31, 2022

Pubmed Data : Egypt J Immunol. 2023 Jan ;30(1):57-72. PMID: 36592119
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Fenugreek
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

Biochanin A in murine Schistosoma mansoni infection: effects on inflammation, oxidative stress and fibrosis.Feb 05, 2023

Pubmed Data : J Helminthol. 2023 Feb 6 ;97:e16. Epub 2023 Feb 6. PMID: 36740983
Article Published Date : Feb 05, 2023
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Inflammation, Oxidative Stress, Schistosomiasis
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants
[+]

Curcumin has positive immunomodulatory effects on mouse schistosomiasis. Jan 01, 2009

Pubmed Data : Immunobiology. 2009;214(8):712-27. Epub 2009 Feb 26. PMID: 19249123
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Schistosomiasis
Pharmacological Actions : Immunomodulatory
[+]

Ferula assafoetida has a therapeutic effect in experimental murine Schistosoma mansoni infection.Feb 01, 2007

Pubmed Data : J Appl Physiol. 2007 Feb;102(2):516-28. Epub 2006 Oct 19. PMID: 15658063
Article Published Date : Feb 01, 2007
Study Type : Animal Study
Additional Links
Substances : Asafoetida
Diseases : Parasitic Diseases, Schistosomiasis
Additional Keywords : Plant Extracts
[+]

Garlic extract and Nigella sativa oil are promising agents to complement schistosomiasis specific treatment.Dec 31, 2007

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rev Inst Med Trop Sao Paulo. 2008 Jan-Feb;50(1):29-36. PMID: 18327484
Article Published Date : Dec 31, 2007
Study Type : Animal Study
Additional Links
Substances : Garlic, Nigella sativa (aka Black Seed)
Diseases : Lipid Peroxidation, Schistosomiasis
Pharmacological Actions : Antioxidants, Antiparasitic Agents
Additional Keywords : Plant Extracts
[+]

Garlic oil extract has activity against S. japonicum larvae and a promising preventive efficacy against S. japonicum infection.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rev Soc Bras Med Trop. 2017 Jan-Feb;50(1):126-129. PMID: 28327815
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Garlic
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Antiparasitic Agents, Garlic, Plant Oils, Schistosomiasis
[+]

Genistein can be a potential natural agent against schistosomiasis.Feb 02, 2017

Pubmed Data : Parasitol Res. 2017 Feb 3. Epub 2017 Feb 3. PMID: 28160073
Article Published Date : Feb 02, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Genistein
Diseases : Schistosomiasis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginger has antischistosomal activity effect against Schistosoma mansoni harbored in mice.Mar 01, 2009

Pubmed Data : Zhongguo Zhen Jiu. 2009 Mar;29(3):247-51. PMID: 21327992
Article Published Date : Mar 01, 2009
Study Type : Animal Study
Additional Links
Substances : Ginger
Diseases : Schistosomiasis
[+]

Hepatosplenic protective actions of Spirulina platensis and matcha green tea against Schistosoma mansoni infection.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Vet Sci. 2021 ;8:650531. Epub 2021 Apr 30. PMID: 33996977
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Green Tea, Spirulina
Diseases : Schistosomiasis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-10 upregulation, interleukin-13 down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Immunopathological effects of Agaricus blazei Murill polysaccharides against Schistosoma mansoni infection by Th1 and NK1 cells differentiation.Jul 31, 2019

Pubmed Data : Int Immunopharmacol. 2019 Aug ;73:502-514. Epub 2019 Jun 4. PMID: 31173972
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Agaricus Blazei
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents, Immunomodulatory
Additional Keywords : Polysaccharides
[+]

In silico study of Cucurbita maxima compounds as potential therapeutics against schistosomiasis.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bioinform Biol Insights. 2022 ;16:11779322221100741. Epub 2022 May 20. PMID: 35615403
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Pumpkin
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

Licochalcone A-loaded solid lipid nanoparticles improve antischistosomal activity.Dec 31, 2020

Pubmed Data : Nanomedicine (Lond). 2021 08 ;16(19):1641-1655. Epub 2021 Jul 14. PMID: 34256609
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Licorice
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

Myrrh has significant antiparasitic activity against Schistosomiasis.Dec 01, 2004

Pubmed Data : J Egypt Soc Parasitol. 2004 Dec;34(3 Suppl):1051-76. PMID: 15658062
Article Published Date : Dec 01, 2004
Study Type : Animal Study
Additional Links
Substances : Myrrh
Diseases : Schistosomiasis
[+]

Nigella sativa oil may play a role against the alterations caused by S. mansoni infection.Dec 31, 2001

Pubmed Data : J Ethnopharmacol. 2002 Jan ;79(1):1-11. PMID: 11744288
Article Published Date : Dec 31, 2001
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Schistosomiasis
Pharmacological Actions : Antioxidants
Additional Keywords : Plant Oils
[+]

Paeoniflorin attenuates schistosomiasis japonica-associated liver fibrosisAug 31, 2011

Pubmed Data : Parasitology. 2011 Sep ;138(10):1259-71. Epub 2011 Aug 3. PMID: 21810309
Article Published Date : Aug 31, 2011
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Liver Cirrhosis, Schistosomiasis
Pharmacological Actions : Anti-Fibrotic, interleukin-13 down-regulation
[+]

Paeoniflorin is predicted to be a potential therapy for chronic hepatic diseases associated with fibrosis and angiogenesis.Jan 31, 2019

Pubmed Data : Exp Parasitol. 2019 Feb ;197:85-92. Epub 2018 Nov 8. PMID: 30414842
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Liver Disease, Schistosomiasis
Pharmacological Actions : Anti-Angiogenic, Anti-Fibrotic, Vascular Endothelial Growth Factor Inhibitors
[+]

Parasitological and biochemical efficacy of the active ingredients of Allium sativum and Curcuma longa in Schistosoma mansoni infected mice.Jul 26, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2021 Jul 27 ;26(15). Epub 2021 Jul 27. PMID: 34361695
Article Published Date : Jul 26, 2021
Study Type : Animal Study
Additional Links
Substances : Garlic, Turmeric
Diseases : Schistosomiasis
Pharmacological Actions : Antioxidants, Antiparasitic Agents, Hepatoprotective
[+]

Rutin has strong anti-schistosome properties in vivo.Feb 27, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Feb 28 ;15(5). Epub 2023 Feb 28. PMID: 36904204
Article Published Date : Feb 27, 2023
Study Type : Animal Study
Additional Links
Substances : Rutin
Diseases : Schistosomiasis
Pharmacological Actions : Anti-Inflammatory Agents, Antiparasitic Agents, Immunomodulatory
[+]

These findings represent the promising anti-schistosomal activities of probiotics and yogurt.Jan 02, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2019 Jan 3 ;19(1):3. Epub 2019 Jan 3. PMID: 30606163
Article Published Date : Jan 02, 2019
Study Type : Animal Study
Additional Links
Substances : Probiotics, Yoghurt
Diseases : Lipid Peroxidation, Liver Cirrhosis, Oxidative Stress, Schistosomiasis
Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic, Antioxidants, Hepatoprotective, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Use of wogonin as a cooperative drug with praziquantel to better combat schistosomiasis.Jul 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Microbiol Immunol Infect. 2022 Aug ;55(4):757-765. Epub 2022 May 17. PMID: 35654701
Article Published Date : Jul 31, 2022
Study Type : Animal Study
Additional Links
Substances : Wogonin
Diseases : Schistosomiasis
Pharmacological Actions : Anthelmintics
Additional Keywords : Natural Substance/Drug Synergy
[+]

A systematic review on antimicrobial and antiparasitic activity of Eurycoma longifolia Jack.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2022 ;2022:4999797. Epub 2022 Jul 6. PMID: 35845951
Article Published Date : Dec 31, 2021
Study Type : Review
Additional Links
Substances : Tongkat Ali
Diseases : Bacillus Cereus infection, Bacillus subtilis infections, Candida Albicans, Escherichia coli Infections, Plasmodium Infections, Pseudomonas aeruginosa, Schistosomiasis, Shigellosis, Staphylococcus aureus infection, Steptococcus Mutans Infections
Pharmacological Actions : Anti-Bacterial Agents, Antimicrobial, Antiparasitic Agents
Additional Keywords : Plant Extracts
[+]

Camu-camu seeds as a novel source of bioactive compounds with promising antimalarial and antischistosomicidal properties.Sep 30, 2020

Pubmed Data : Food Res Int. 2020 Oct ;136:109334. Epub 2020 May 19. PMID: 32846532
Article Published Date : Sep 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Camu Camu
Diseases : Malaria, Schistosomiasis
Pharmacological Actions : Antimalarials, Antiparasitic Agents
[+]

Cardamonin presents in vivo activity against Schistosoma mansoni.Oct 31, 2021

Pubmed Data : Chem Biodivers. 2021 Nov ;18(11):e2100604. Epub 2021 Oct 27. PMID: 34608744
Article Published Date : Oct 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Cardamonin
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents, Enzyme Inhibitors
Additional Keywords : Plant Extracts
[+]

Curcumin has schistosomicidal activity.Mar 01, 2009

Pubmed Data : Acta Pharmacol Sin. 2009 Mar;30(3):227-81. PMID: 19096877
Article Published Date : Mar 01, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Parasitic Diseases, Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

Dandelion improves the therapeutic efficiency of praziquantel in experimental Schistosomiasis.Jan 23, 2022

Pubmed Data : Acta Parasitol. 2022 Jan 24. Epub 2022 Jan 24. PMID: 35067863
Article Published Date : Jan 23, 2022
Study Type : In Vitro Study
Additional Links
Substances : Dandelion
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Natural Substance/Drug Synergy
[+]

Ganoderma lucidum extract inhibits Schistosoma mansoni survival in silico and in vitro study.Dec 31, 2021

Pubmed Data : Ann Parasitol. 2022 ;68(2):323-330. PMID: 35810364
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Reishi Mushroom
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

Licochalcone A induces morphological and biochemical alterations in Schistosoma mansoni adult worms.Nov 30, 2017

Pubmed Data : Biomed Pharmacother. 2017 Dec ;96:64-71. Epub 2017 Nov 24. PMID: 28965009
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Licorice
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Plant Extracts
[+]

Pumpkin-seed oil possesses effective antischistosomal activity against various stages of S. mansoni.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Infect Drug Resist. 2020 ;13:3469-3484. Epub 2020 Oct 7. PMID: 33116667
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Pumpkin Seed Oil/Meal
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
[+]

The findings suggest that T. vulgare is a potential source of schistosomicidal compounds.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ScientificWorldJournal. 2014 ;2014:460342. Epub 2014 Feb 2. PMID: 24672320
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Tansy
Diseases : Schistosomiasis
Pharmacological Actions : Antiparasitic Agents
Additional Keywords : Essential Oils
[+]

Tongkat Ali (Euycoma longifolia) exhibits anti-tumor, anti-schistomosomal and ant-malarial activity, in vito. Sep 01, 2002

Pubmed Data : J Ethnopharmacol. 2002 Sep;82(1):55-8. PMID: 12169407
Article Published Date : Sep 01, 2002
Study Type : In Vitro Study
Additional Links
Substances : Tongkat Ali
Diseases : Malaria, Schistosomiasis, Tumors
Pharmacological Actions : Anti-Tumor, Antimalarials

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