Scleroderma: Systemic

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5 Substances Researched for Scleroderma: Systemic

Name	AC	CK
Vitamin D	1	20
Tanshinone IIA	1	2
Baicalein	1	1
Peony	1	1
Red Sage	1	1

1 Problem Substances Researched for Scleroderma: Systemic

Name	AC	CK	Focus
Antibiotics	1	2

2 Therapeutic Actions Researched for Scleroderma: Systemic

Name	AC	CK	Focus
Thermal Therapy: Far-Infrared	1	10
Photobiomodulation	1	3

Research Articles 10
Cumulative Knowledge Score 16
Overall Research Rating GOOD

View the Evidence:
10 Abstracts with Scleroderma: Systemic Research

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[+]

Systemic sclerosis patients exhibited lower vitamin D levels compared with healthy controls.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Drug Des Devel Ther. 2017 ;11:3119-3125. Epub 2017 Oct 27. PMID: 29138534

Article Published Date : Dec 31, 2016

Study Type : Meta Analysis

Additional Links

Substances : Vitamin D

Diseases : Scleroderma: Systemic , Vitamin D Deficiency

[+]

Therapeutic mud applications may benefit cardiovascular patients with rheumatoid arthritis, osteoarthrosis and systemic scleroderma.Dec 01, 2003

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Pubmed Data : Complement Ther Med. 2003 Dec;11(4):226-34. PMID: 4081998

Article Published Date : Dec 01, 2003

Study Type : Human Study

Additional Links

Diseases : Cardiovascular Diseases, Osteoarthrosis, Rheumatoid Arthritis, Scleroderma: Systemic

[+]

Three out of the seven patients reported lower frequency and severity of Raynaud attacks.Dec 31, 1989

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Pubmed Data : Dermatol Monatsschr. 1990 ;176(11):683-6. PMID: 2083608

Article Published Date : Dec 31, 1989

Study Type : Human Study

Additional Links

Diseases : Scleroderma: Systemic

Therapeutic Actions : Thermal Therapy: Far-Infrared

[+]

Pulsed versus continuous wave low-level light therapy on osteoarticular signs and symptoms in limited scleroderma (CREST syndrome): a case report.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Biomed Opt. 2014 ;19(11):118001. PMID: 25393970

Article Published Date : Dec 31, 2013

Study Type : Human: Case Report

Additional Links

Diseases : Scleroderma: Systemic

Therapeutic Actions : Photobiomodulation

[+]

Early life antibiotic exposure causes intestinal dysbiosis and exacerbates skin and lung pathology in experimental systemic sclerosis.Jul 26, 2017

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Pubmed Data : J Invest Dermatol. 2017 Jul 27. Epub 2017 Jul 27. PMID: 28757138

Article Published Date : Jul 26, 2017

Study Type : Animal Study

Additional Links

Diseases : Antibiotic Toxicity , Dysbiosis, Scleroderma: Systemic

Problem Substances : Antibiotics

[+]

Tanshinone IIA ameliorates the bleomycin-induced endothelial-to-mesenchymal transition.Nov 30, 2019

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Pubmed Data : Int Immunopharmacol. 2019 Dec ;77:105968. Epub 2019 Nov 6. PMID: 31704290

Article Published Date : Nov 30, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Tanshinone IIA

Diseases : Pulmonary Fibrosis: Bleomycin-Induced, Scleroderma: Systemic

Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents

[+]

Baicalein alleviates fibrosis and inflammation in systemic sclerosis.Feb 20, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Med Ther. 2023 Feb 21 ;23(1):62. Epub 2023 Feb 21. PMID: 36810081

Article Published Date : Feb 20, 2023

Study Type : In Vitro Study

Additional Links

Substances : Baicalein

Diseases : Scleroderma: Systemic

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents

[+]

Red sage contains compounds with antifibrotic activity that may prove useful in the treatment of systemic sclerosis. Sep 11, 2007

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Pubmed Data : : Zhonghua Yi Xue Za Zhi. 2007 Sep 11;87(34):2426-8. PMID: 18036324

Article Published Date : Sep 11, 2007

Study Type : In Vitro Study

Additional Links

Substances : Red Sage

Diseases : Scleroderma, Scleroderma: Systemic

Pharmacological Actions : Fibrinolytic Agents

[+]

SARS-CoV-2 spike protein accelerates systemic sclerosis by increasing inflammatory cytokines, Th17 cells, and fibrosis.Dec 20, 2023

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Inflamm (Lond). 2023 Dec 21 ;20(1):46. Epub 2023 Dec 21. PMID: 38129904

Article Published Date : Dec 20, 2023

Study Type : In Vitro Study

Additional Links

Diseases : Coronavirus Disease (Covid-19), Scleroderma: Systemic

Additional Keywords : SARS-CoV-2 Spike Protein

Adverse Pharmacological Actions : Inflammatory

[+]

Total glucosides of paeony alleviates scleroderma by inhibiting type I interferon responses.Feb 09, 2023

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Pubmed Data : J Ethnopharmacol. 2023 Feb 10 ;302(Pt A):115897. Epub 2022 Nov 2. PMID: 36334818

Article Published Date : Feb 09, 2023

Study Type : In Vitro Study

Additional Links

Substances : Peony

Diseases : Scleroderma: Systemic

Pharmacological Actions : Anti-Fibrotic, Immunomodulatory

Research Articles 10
Cumulative Knowledge Score 16
Overall Research Rating GOOD

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 10 Abstracts with Scleroderma: Systemic Research

Limited to Members Only

Currently Available Sorting Options

Systemic sclerosis patients exhibited lower vitamin D levels compared with healthy controls.Dec 31, 2016

Therapeutic mud applications may benefit cardiovascular patients with rheumatoid arthritis, osteoarthrosis and systemic scleroderma.Dec 01, 2003

Three out of the seven patients reported lower frequency and severity of Raynaud attacks.Dec 31, 1989

Pulsed versus continuous wave low-level light therapy on osteoarticular signs and symptoms in limited scleroderma (CREST syndrome): a case report.Dec 31, 2013

Early life antibiotic exposure causes intestinal dysbiosis and exacerbates skin and lung pathology in experimental systemic sclerosis.Jul 26, 2017

Tanshinone IIA ameliorates the bleomycin-induced endothelial-to-mesenchymal transition.Nov 30, 2019

Baicalein alleviates fibrosis and inflammation in systemic sclerosis.Feb 20, 2023

Red sage contains compounds with antifibrotic activity that may prove useful in the treatment of systemic sclerosis. Sep 11, 2007

SARS-CoV-2 spike protein accelerates systemic sclerosis by increasing inflammatory cytokines, Th17 cells, and fibrosis.Dec 20, 2023

Total glucosides of paeony alleviates scleroderma by inhibiting type I interferon responses.Feb 09, 2023

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Scleroderma: Systemic

View the Evidence:
10 Abstracts with Scleroderma: Systemic Research