Seizures: Drug-Induced

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7 Substances Researched for Seizures: Drug-Induced
NameACCKFocus
Bitter Apple12Locked
Coriandrum sativum12Locked
Curcumin12Locked
Dill12Locked
Grape12Locked
Motherwort12Locked
Rose 12Locked
4 Problem Substances Researched for Seizures: Drug-Induced
NameACCKFocus
Isoniazid220Locked
Proton-Pump Inhibitors13Locked
Hypnotic Drugs22Locked
Zolpidem (trade name Ambien)22Locked

View the Evidence:
22 Abstracts with Seizures: Drug-Induced Research

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Acute isoniazid intoxication has been associated with seizures, acidosis and coma.Aug 01, 1999

Pubmed Data : Acta Clin Belg. 1999 Aug;54(4):211-6. PMID: 10544512
Article Published Date : Aug 01, 1999
Study Type : Human Study
Additional Links
Diseases : Acidosis, Coma, Seizures: Drug-Induced
Problem Substances : Isoniazid
[+]

Isoniazid has been associated with seizures and acute neurotoxicity in childhood.May 01, 1995

Pubmed Data : Pediatrics. 1995 May;95(5):700-4. PMID: 7724306
Article Published Date : May 01, 1995
Study Type : Human Study
Additional Links
Diseases : Seizures: Drug-Induced, Tuberculosis
Problem Substances : Isoniazid
[+]

"A patient on long-term proton pump inhibitors develops sudden seizures and encephalopathy"Dec 31, 2011

Pubmed Data : Case Rep Gastrointest Med. 2012 ;2012:632721. Epub 2012 Nov 18. PMID: 23213582
Article Published Date : Dec 31, 2011
Study Type : Human: Case Report
Additional Links
Diseases : Encephalopathies, Magnesium Deficiency, Seizures: Drug-Induced
Problem Substances : Proton-Pump Inhibitors
[+]

A hydro-alcoholic extract of Dill seed demonstrated anticonvulsant activity against PTZ-induced seizures.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Basic Clin Neurosci. 2014 ;5(3):199-204. PMID: 25337380
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Dill
Diseases : Seizures, Seizures: Drug-Induced
Pharmacological Actions : Anticonvulsants
Additional Keywords : Plant Extracts
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A hydro-alcoholic extract of R. dam ascena has anticonvulsant and neuroprotective effects.Apr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2015 May-Jun;5(3):260-70. PMID: 26101759
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Rose
Diseases : Seizures, Seizures: Drug-Induced
Pharmacological Actions : Anticonvulsants, Neuroprotective Agents
Additional Keywords : Plant Extracts
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Anti-inflammation associated protective mechanism of berberine and its derivatives on attenuating pentylenetetrazole-induced seizures.Jan 05, 2020

Pubmed Data : J Neuroimmune Pharmacol. 2020 Jan 6. Epub 2020 Jan 6. PMID: 31909440
Article Published Date : Jan 05, 2020
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Epilepsy, Seizures: Drug-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Anticonvulsants
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Bitter apple has significant anticonvulsant effects in pentylenetetrazole-induced seizures in miceDec 02, 2015

Pubmed Data : J Evid Based Complementary Altern Med. 2015 Dec 3. Epub 2015 Dec 3. PMID: 26634927
Article Published Date : Dec 02, 2015
Study Type : Animal Study
Additional Links
Substances : Bitter Apple
Diseases : Seizures: Drug-Induced
Pharmacological Actions : Anticonvulsants
Additional Keywords : Plant Extracts
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Curcumin protects against seizures and cognitive impairment in a drug-induced epileptic rat model.Sep 16, 2010

Pubmed Data : Life Sci. 2010 Sep 16. Epub 2010 Sep 16. PMID: 20840851
Article Published Date : Sep 16, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Epilepsy, Seizures, Seizures: Drug-Induced
Pharmacological Actions : Anticonvulsants
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Different fractions of C. sativum aerial parts possess antioxidant activity in the brain.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2016 Mar-Apr;6(2):223-35. PMID: 27222836
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Coriandrum sativum
Diseases : Seizures, Seizures: Drug-Induced
Pharmacological Actions : Anticonvulsants, Antioxidants, Malondialdehyde Down-regulation
Additional Keywords : Plant Extracts
[+]

Effects of aqueous extract of Hyssopus officinalis on seizures induced by pentylenetetrazole.Apr 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2020 May-Jun;10(3):213-221. PMID: 32523876
Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Substances : Hyssop
Diseases : Seizures: Drug-Induced
Pharmacological Actions : Anticonvulsants
[+]

Embelin protects against acute pentylenetetrazole-induced seizures and positively modulates cognitive function.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:1249. Epub 2019 Oct 25. PMID: 31708779
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : False Black Pepper
Diseases : Seizures: Drug-Induced
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Natural Substance/Drug Synergy
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Mice with decreased ascorbic acid had increased oxidative stress in brain, increased mortality and faster seizure onset.Jan 31, 2015

Pubmed Data : Epilepsy Res. 2015 Feb ;110:20-5. Epub 2014 Nov 26. PMID: 25616451
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Alzheimer's Disease, Epilepsy, Seizures, Seizures: Drug-Induced, Vitamin C Deficiency
Additional Keywords : Risk Factors, Risk Reduction
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Motherwort has anticonvulsant activity against chemically induced seizures in the mouse model.Apr 01, 2002

Pubmed Data : Phytomedicine. 2002 Apr;9(3):217-23. PMID: 12046862
Article Published Date : Apr 01, 2002
Study Type : Animal Study
Additional Links
Substances : Motherwort
Diseases : Seizures: Drug-Induced
[+]

Organic grape juice has superior neuroprotective properties in a seizure-induced animal model of neurological oxidative stress. Mar 24, 2012

Pubmed Data : Neurochem Int. 2012 Mar 24. Epub 2012 Mar 24. PMID: 22465942
Article Published Date : Mar 24, 2012
Study Type : Animal Study
Additional Links
Substances : Grape
Diseases : Seizures: Drug-Induced
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Organic Versus Conventional
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Orthosiphon stamineus proteins alleviate pentylenetetrazol-induced seizures.Jul 01, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomedicines. 2020 Jul 2 ;8(7). Epub 2020 Jul 2. PMID: 32630817
Article Published Date : Jul 01, 2020
Study Type : Animal Study
Additional Links
Substances : Orthosiphon
Diseases : Seizures: Drug-Induced
Pharmacological Actions : Anticonvulsants
[+]

Rosmarinic acid is anticonvulsant against seizures induced by pentylenetetrazol and pilocarpine in mice.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Epilepsy Behav. 2016 09 ;62:27-34. Epub 2016 Jul 20. PMID: 27448240
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Rosemaric Acid
Diseases : Seizures: Drug-Induced
Pharmacological Actions : Anticonvulsants
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Tangeretin exerted potent neuroprotective effects against pilocarpine-induced seizures.Aug 31, 2017

Pubmed Data : Adv Med Sci. 2017 Sep ;62(2):246-253. Epub 2017 May 11. PMID: 28501723
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Tangeretin
Diseases : Seizures: Drug-Induced
Pharmacological Actions : Anticonvulsants, Neuroprotective Agents
Additional Keywords : Anticonvulsants, Neuroprotective Agents, Seizures: Drug-Induced, Tangeretin
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Valerenic acid and valerian extracts have anticonvulsant properties in adult zebrafish. Jul 13, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2015 Jul 14 ;15:228. Epub 2015 Jul 14. PMID: 26168917
Article Published Date : Jul 13, 2015
Study Type : Animal Study
Additional Links
Substances : Valerian
Diseases : Seizures: Drug-Induced
Pharmacological Actions : Anticonvulsants
Additional Keywords : Natural Substance/Drug Synergy, Plant Extracts
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Ferulic acid ameliorates pentylenetetrazol-induced seizures by reducing neuron cell death.Aug 04, 2019

Pubmed Data : Epilepsy Res. 2019 Aug 5 ;156:106183. Epub 2019 Aug 5. PMID: 31404716
Article Published Date : Aug 04, 2019
Study Type : In Vitro Study
Additional Links
Substances : Ferulic acid
Diseases : Seizures: Drug-Induced
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
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Galangin prevents increased susceptibility to pentylenetetrazol-stimulated seizures by prostaglandin E2.Jan 09, 2019

Pubmed Data : Neuroscience. 2019 08 10 ;413:154-168. Epub 2019 Jun 11. PMID: 31200106
Article Published Date : Jan 09, 2019
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Inflammation, Seizures: Drug-Induced
Pharmacological Actions : Anti-Inflammatory Agents, Anticonvulsants, Postaglandin PGE2 downregulation
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Seizure following sudden zolpidem withdrawal has been reported.Mar 30, 2007

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2007 Mar 30;31(2):539-40. Epub 2006 Sep 6. PMID: 16950552
Article Published Date : Mar 30, 2007
Study Type : Commentary
Additional Links
Diseases : Seizures, Seizures: Drug-Induced
Problem Substances : Hypnotic Drugs, Zolpidem (trade name Ambien)
Adverse Pharmacological Actions : Addictive
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Zolpidem abuse, dependence and withdrawal reactions have been reported.Jul 01, 2009

Pubmed Data : Rev Med Liege. 2009 Jul-Aug;64(7-8):407-8. PMID: 19777922
Article Published Date : Jul 01, 2009
Study Type : Commentary
Additional Links
Diseases : Seizures: Drug-Induced
Problem Substances : Hypnotic Drugs, Zolpidem (trade name Ambien)

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