Sepsis

Name	AC	CK
Vitamin C	43	168
Vitamin D	18	127
Lactoferrin	9	73
Probiotics	6	61
Vitamin C: Intravenous	10	49
Omega-3 Fatty Acids	4	44
Thiamine (B-1)	6	42
Coenzyme Q10	6	35
Melatonin	11	32
Selenium	3	32
L-Carnitine	2	30
Lactobacillus rhamnosus GG	6	28
Ginsenosides	16	25
Berberine	15	24
Lactobacillus Acidophilus	2	20
Emodin	9	16
Flavonoids	10	16
Curcumin	10	15
Resveratrol	8	15
Thymoquinone	8	14
Vitamin B-6	3	14
NAC (N-acetyl-L-cysteine)	3	12
Puerarin	5	12
Vitamin E	2	12
Astragaloside	7	11
Citrus naringin	7	11
Tanshinone IIA	6	11
Bifidobacterium Bifidum	1	10
Coconut Oil	1	10
Homeopathic Medicine: All	1	10
Lactobacillus plantarum	1	10
Luteolin	5	10
Paeoniflorin	6	10
Polyphenols	4	10
Vitamin A	1	10
Allicin	4	8
Hydrogen: Molecular	4	8
Quercetin	5	8
Andrographolide	3	7
Cannabidiol	4	7
Ginger	2	7
Pterostilbene	3	7
Artesunate	3	6
Astaxanthin	3	6
Bee Venom	4	6
Chrysin	3	6
Fisetin	3	6
Fucoxanthin	4	6
Gingerol	4	5
Ginseng (Korean)	3	5
Kaempferol	3	5
Myricetin	3	5
Aloe Vera	2	4
Baicalein	2	4
Carnosol	2	4
Celastrol	2	4
EPA (Eicosapentaenoic Acid)	2	4
Genipin	2	4
Ginkgo biloba	2	4
Glycyrrhizin	2	4
Hesperidin	2	4
Honokiol	2	4
Hydrogen Water	2	4
Isoliquiritigenin	2	4
Ligustrazine	2	4
Mangiferin	2	4
Oleuropein	2	4
Olive Oil	2	4
Parthenolide	2	4
Piperine	3	4
Pomegranate	2	4
Poria cocos	2	4
Procyanidin B2	2	4
Red Sage	2	4
Reishi Mushroom	2	4
Riboflavin (Vitamin B-2)	2	4
Rooibos	2	4
Rose	2	4
Rosemaric Acid	2	4
Shitake Mushroom	2	4
Sinomenine	2	4
Sulforaphane	2	4
Tangeretin	2	4
Water: Deuterium Depleted	2	4
Alpha-Lipoic Acid	2	3
Apigenin	2	3
Beta-Caryophyllene	2	3
Carvacrol	2	3
Citrulline	2	3
Fish Oil	2	3
Honeysuckle	2	3
Lotus	2	3
Peony	1	3
Safflower	2	3
Algae	1	2
Angelica	1	2
Apocynin	1	2
Astragalus	1	2
Babchi	1	2
Beta-glucan	1	2
Betulinic acid	1	2
Black Tea	1	2
Butyrate	1	2
Cannabis	1	2
Capsaicin	2	2
Catechin	1	2
Celery	1	2
Cinnamaldehyde	1	2
Cordyceps Militaris	1	2
Cordyceps sinensis	1	2
Crocin	1	2
Cucurbitacin B	1	2
Cyanidin 3-glucoside	1	2
DHA (Docosahexaenoic Acid)	1	2
Diosmin	1	2
Dogwood	1	2
EGCG (Epigallocatechin gallate)	1	2
Ferulic acid	1	2
Fiber	1	2
Folic Acid	1	2
Gardenia	1	2
Garlic	1	2
Gastrodin	1	2
Goji	1	2
Green Tea	1	2
Guduchi	1	2
Honey	1	2
Huperzine	1	2
Hydroxytyrosol	1	2
Isoflavones	1	2
Isothiocyanates	1	2
Kombucha Tea	1	2
Kudzu	1	2
Lactobacillus casei	1	2
Lactobacillus gasseri	1	2
Licorice	1	2
Lycopene	1	2
Magnesium	1	2
Mint	1	2
Moringa oleifera	1	2
Mulberry	1	2
Naringenin	2	2
Niacin	1	2
Nobiletin	1	2
Olive leaf extract	1	2
Oridonin	1	2
Palm Oil	1	2
Palmitoylethanolamide	1	2
Panax Notoginseng	1	2
Phloretin	1	2
Piperlongumine	1	2
Potato	1	2
Propolis: Bee	1	2
Pycnogenol (Pine Bark)	1	2
Red Marine Algae	1	2
Rhubarb	1	2
Rosmarinic acid	1	2
Sesame Seed Oil	1	2
Sesamin	1	2
Sesamol	1	2
Shiitake Mushroom	1	2
Shikonin	1	2
Silibinin	1	2
Terminalia	1	2
Theanine	1	2
Tomatidine	1	2
Toona sinensis	1	2
Verbascoside	1	2
Vitamin B-3 (Niacin)	1	2
Vitexins	1	2
Wogonin	2	2
Xanthohumol	1	2
Zataria multiflora	1	2
Chicoric Acid	1	1
Crocetin	1	1
Echinacea	1	1
Elecampane	1	1
Fucoidan	1	1
Gold (nanoparticles)	1	1
Grape Seed Extract	1	1
Harmine	1	1
Magnolol	1	1
Piceatannol	1	1
Turmeric	1	1
Verbena officinalis	1	1

Name	AC	CK
Infant Formula	2	11
Atorvastatin	1	10
Morphine	1	10
Statin Drugs	1	10
Antibiotics	2	3
Bisphenol A	1	2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	2

Name	AC	CK
Electroacupuncture	9	18
Acupuncture	3	14
Dietary Modification: Low Carbohydrate/Ketogenic	1	10
Homeopathic Treatment	1	10
Microbiota Transfer Therapy	1	2
Light Therapy	1	1

Name	AC	CK	Focus
Vaccination: All	2	20
Western Diet	3	5

[+]

The role and efficacy of vitamin C in sepsis.Jul 27, 2022

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Pubmed Data : Clin Nutr ESPEN. 2024 Feb ;59:126-134. Epub 2023 Dec 1. PMID: 38220365

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Pubmed Data : Biochem Cell Biol. 2020 Sep 15. Epub 2020 Sep 15. PMID: 32931708

Article Published Date : Sep 14, 2020

Study Type : Human Study

Additional Links

Substances : Lactoferrin

Diseases : Sepsis

Additional Keywords : Risk Reduction

[+]

Coenzyme Q10 improves the survival and reduces inflammatory markers in septic patients.Dec 31, 2019

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Pubmed Data : Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2023 Dec ;35(12):1268-1273. PMID: 38149388

Article Published Date : Nov 30, 2023

Study Type : Human Study

Additional Links

Substances : Probiotics

Diseases : Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents

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NAC plus antibiotics might reduce the 30-day mortality rate in ICU patients with CR-Kp and CR-Ab septic shock.Mar 07, 2021

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Pubmed Data : Antibiotics (Basel). 2021 Mar 8 ;10(3). Epub 2021 Mar 8. PMID: 33800296

Article Published Date : Mar 07, 2021

Study Type : Human Study

Additional Links

Substances : NAC (N-acetyl-L-cysteine)

Diseases : Klebsiella Infections, Sepsis, Septic Shock

Additional Keywords : Risk Reduction

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Neonates with vitamin D deficiency/insufficiency are at higher risk for developing sepsis.Feb 12, 2020

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Pubmed Data : Indian J Pediatr. 2020 Feb 13. Epub 2020 Feb 13. PMID: 32056191

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Pubmed Data : Br J Nutr. 2017 Apr ;117(7):994-1000. Epub 2017 Apr 26. PMID: 28443531

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Pubmed Data : Shock. 2024 Jun 1 ;61(6):841-847. Epub 2024 Apr 26. PMID: 38691102

Article Published Date : May 31, 2024

Study Type : Human Study

Additional Links

Substances : Vitamin B-6

Diseases : Oxidative Stress, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Interleukin-8 downregulation, Malondialdehyde Down-regulation, Renoprotective, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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The association between vitamin D deficiency/lower 25(OH)D levels and sepsis was significant in children and neonates. Aug 26, 2019

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Pubmed Data : Clin Nutr. 2019 Aug 27. Epub 2019 Aug 27. PMID: 31495735

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Pubmed Data : Chest. 2017 11 ;152(5):954-962. Epub 2017 Jul 21. PMID: 28739448

Article Published Date : Jan 10, 2017

Study Type : Human In Vitro

Additional Links

Substances : Vitamin C

Diseases : Endothelial Dysfunction, Lipopolysaccharide-Induced Toxicity, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Natural Substance/Drug Synergy

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Puerarin inhibited ferroptosis and inflammation of lung injury caused by sepsis.Dec 31, 2020

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The results suggested that the protective effects of Loganin on AKI during sepsis might be mediated by AKT and Nrf2/HO-1 pathway.Dec 31, 2020

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Pubmed Data : Drug Des Devel Ther. 2021 ;15:501-513. Epub 2021 Feb 11. PMID: 33603340

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Dogwood

Diseases : Kidney Damage, Sepsis

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, Renoprotective

[+]

A cecal slurry mouse model of sepsis leads to acute consumption of vitamin C in the brain.Mar 25, 2020

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Pubmed Data : Nutrients. 2020 Mar 26 ;12(4). Epub 2020 Mar 26. PMID: 32224930

Article Published Date : Mar 25, 2020

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Brain Inflammation , Sepsis, Vitamin C Deficiency

Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents

Additional Keywords : Risk Factors

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A combination of ascorbate with Amphotericin B is a potentially effective treatment that may reduce nephrotoxicity in patients with systemic candidiasis.Jul 31, 2015

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Pubmed Data : Am J Physiol Regul Integr Comp Physiol. 2015 Aug 1 ;309(3):R223-34. PMID: 25994956

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Pubmed Data : Am J Chin Med. 2019 ;47(3):613-633. Epub 2019 Apr 9. PMID: 30966773

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Aloe Vera

Diseases : Sepsis

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation, SIRT1 Activator

Additional Keywords : Phytotherapy

[+]

Ameliorative effect of aspalathin and nothofagin from rooibos on HMGB1-induced septic responses.Dec 31, 2014

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Pubmed Data : Am J Chin Med. 2015 ;43(5):991-1012. Epub 2015 Jul 30. PMID: 26224030

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Pubmed Data : J Sci Food Agric. 2019 Jun 17. Epub 2019 Jun 17. PMID: 31206687

Article Published Date : Jun 16, 2019

Study Type : Animal Study

Additional Links

Substances : Beta-Caryophyllene, DHA (Docosahexaenoic Acid)

Diseases : Sepsis, Staphylococcus aureus infection

Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-4 upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

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Pubmed Data : Zhonghua Yi Xue Za Zhi. 2020 Sep 22 ;100(35):2779-2784. PMID: 32972060

Article Published Date : Sep 21, 2020

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Cardiomyopathy, Lipopolysaccharide-Induced Toxicity, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Berberine exerted a protective effect on gut-vascular barrier function in sepsis.Sep 10, 2018

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Pubmed Data : Cell Physiol Biochem. 2018 Sep 11 ;49(4):1342-1351. Epub 2018 Sep 11. PMID: 30205381

Article Published Date : Sep 10, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Berberine

Diseases : Sepsis

Pharmacological Actions : Gastroprotective

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C. sinensis can improve the dysfunction of gut barrier in septic rats by promoting the proliferation and inhibiting the apoptosis of intestinal mucosal cells.Dec 31, 2014

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Pubmed Data : Int J Clin Exp Med. 2015 ;8(5):7333-41. Epub 2015 May 15. PMID: 26221273

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Cordyceps sinensis

Diseases : Sepsis

Pharmacological Actions : Anti-Apoptotic, Gastroprotective

[+]

Cannabidiol effect on long-term brain alterations in septic rats.Mar 31, 2024

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Pubmed Data : Brain Res. 2024 Apr 1 ;1828:148771. Epub 2024 Jan 17. PMID: 38242525

Article Published Date : Mar 31, 2024

Study Type : Animal Study

Additional Links

Substances : Cannabidiol

Diseases : Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Brain-derived neurotrophic factor modulator, Neuroprotective Agents

[+]

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Pubmed Data : J Surg Res. 2023 May ;285:51-58. Epub 2023 Jan 12. PMID: 36640610

Article Published Date : Apr 30, 2023

Study Type : Animal Study

Additional Links

Substances : Apocynin, Vitamin B-3 (Niacin)

Diseases : Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Combination therapy of niacin and selenium attenuated lung injury and improved survival during sepsis. Dec 01, 2015

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Pubmed Data : Crit Care Med. 2015 Dec 2. Epub 2015 Dec 2. PMID: 26646455

Article Published Date : Dec 01, 2015

Study Type : Animal Study

Additional Links

Substances : Niacin, Selenium

Diseases : Sepsis

Pharmacological Actions : Antioxidants, Nrf2 activation

Additional Keywords : Natural Substance Synergy

[+]

Combination therapy with resveratrol and celastrol using folic acid-functionalized exosomes enhances the therapeutic efficacy of sepsis.Oct 31, 2023

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Pubmed Data : J Trauma. 1991 Jun;31(6):768-73; discussion 773-4. PMID: 2056540

Article Published Date : Jun 01, 1991

Study Type : Animal Study

Additional Links

Substances : Fish Oil

Diseases : Sepsis

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Dietary supplementation with cellulose offers a microbe-mediated survival advantage in murine models of sepsis.Feb 28, 2017

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Pubmed Data : Crit Care Med. 2017 Mar 1. Epub 2017 Mar 1. PMID: 28252538

Article Published Date : Feb 28, 2017

Study Type : Animal Study

Additional Links

Substances : Fiber

Diseases : Sepsis

Additional Keywords : Microbiota

Problem Substances : Antibiotics

[+]

Effect of Sulforaphane on cardiac injury induced by sepsis.Jun 30, 2023

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Pubmed Data : Cell Biochem Funct. 2023 Jun ;41(4):423-433. Epub 2023 Mar 27. PMID: 36970761

Article Published Date : May 31, 2023

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Lipopolysaccharide-Induced Toxicity, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Fecal microbiota transplantation regulates the cholinergic anti-inflammatory pathway in cerebral cortex of septic rats.Aug 31, 2019

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Pubmed Data : Front Pharmacol. 2024 ;15:1374179. Epub 2024 Jun 5. PMID: 38904004

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Pubmed Data : Aging (Albany NY). 2024 Apr 19 ;16. Epub 2024 Apr 19. PMID: 38643461

Article Published Date : Apr 18, 2024

Study Type : Animal Study

Additional Links

Substances : Vitamin C: Intravenous

Diseases : Sepsis

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Autophagy Up-regulation, Cardioprotective

[+]

high-fat enteral nutrition is potentially therapeutic in various inflammatory disorders such as sepsis and inflammatory bowel disease (IBD) characterized by an inflammatory response in which TNF-α is prominent and intestinal barrier function is impairedOct 17, 2005

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Pubmed Data : Life Sci. 2020 May 15 ;249:117502. Epub 2020 Mar 3. PMID: 32142764

Article Published Date : May 14, 2020

Study Type : Animal Study

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Substances : Theanine

Diseases : Kidney Damage, Liver Damage, Oxidative Stress, Sepsis

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Renoprotective

[+]

Lactobacillus casei beneficially modulates immuno-coagulative response in an endotoxemia model.Nov 26, 2017

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Pubmed Data : Blood Coagul Fibrinolysis. 2017 Nov 27. Epub 2017 Nov 27. PMID: 29210752

Article Published Date : Nov 26, 2017

Study Type : Animal Study

Additional Links

Substances : Lactobacillus casei

Diseases : Endotoxemia, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Lactobacillus rhamnosus GG as dietary supplement improved survival from lipopolysaccharides-induced sepsis.Nov 30, 2021

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Pubmed Data : Int Immunopharmacol. 2024 Aug 20 ;137:112418. Epub 2024 Jun 18. PMID: 38901244

Article Published Date : Aug 19, 2024

Study Type : Animal Study

Additional Links

Substances : Citrus naringin

Diseases : Lipopolysaccharide-Induced Toxicity, Lung Damage, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Naringin's protective effect in inflammation may be beneficial for the treatment of sepsis.Dec 31, 2015

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[+]

Panax notoginseng alleviates sepsis-induced acute kidney injury.Dec 31, 2021

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Pubmed Data : Evid Based Complement Alternat Med. 2023 ;2023:8759766. Epub 2023 Jan 6. PMID: 36644442

Article Published Date : Dec 31, 2022

Study Type : Animal Study

Additional Links

Substances : Parthenolide

Diseases : Kidney Damage, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Renoprotective

[+]

Photobiomodulation modulates the resolution of inflammation during acute lung injury induced by sepsis.Jan 31, 2019

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Pubmed Data : Lasers Med Sci. 2019 Feb ;34(1):191-199. Epub 2018 Nov 15. PMID: 30443882

Article Published Date : Jan 31, 2019

Study Type : Animal Study

Additional Links

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Piperlongumin improves survival in the mouse model of sepsis.Jul 12, 2022

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Pubmed Data : Dig Dis Sci. 2019 Apr 30. Epub 2019 Apr 30. PMID: 31049763

Article Published Date : Apr 29, 2019

Study Type : Animal Study

Additional Links

Substances : Lactobacillus rhamnosus GG

Diseases : Hepatitis, Liver Damage, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Procyanidin B2 attenuates sepsis-induced acute lung injury.Apr 26, 2023

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Pubmed Data : Acta Histochem Cytochem. 2023 Feb 28 ;56(1):9-19. Epub 2023 Feb 25. PMID: 36890848

Article Published Date : Feb 27, 2023

Study Type : Animal Study

Additional Links

Substances : Silibinin

Diseases : Liver Damage, Sepsis

Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

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Pubmed Data : Phytother Res. 2014 Nov ;28(11):1692-700. Epub 2014 Jun 11. PMID: 24919414

Article Published Date : Oct 31, 2014

Study Type : Animal Study

Additional Links

Substances : Pycnogenol (Pine Bark)

Diseases : DNA damage, Oxidative Stress, Sepsis

Pharmacological Actions : DNA Repair Up-regulation, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Quercetin exerts cardiovascular protective effects in lipopolysaccharide-induced dysfunction.Jan 09, 2018

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Pubmed Data : Mol Cell Biochem. 2018 Jan 10. Epub 2018 Jan 10. PMID: 29322353

[+]

Riboflavin represents a promising strategy for the treatment of sepsis and septic shock. May 25, 2004

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Pubmed Data : Eur J Pharmacol. 2004 May 25;492(2-3):273-80. PMID: 15178375

Article Published Date : May 25, 2004

Study Type : Animal Study

Additional Links

Substances : Riboflavin (Vitamin B-2)

Diseases : Lipopolysaccharide-Induced Toxicity, Sepsis, Septic Shock

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The role and efficacy of vitamin C in sepsis.Jul 27, 2022

Administration of omega-3 fatty acids could reduce the risk of new-organ failure in patients with acute pancreatitis.Dec 15, 2019

Enteral lactoferrin supplementation for preventing sepsis and necrotizing enterocolitis in preterm infants.Dec 31, 2019

Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis.Oct 10, 2018

L-carnitine patients with higher SOFA score can reduce the mortality rate.Jul 26, 2020

Probiotic and synbiotic supplementation can significantly decrease postoperative sepsis in elective gastrointestinal surgical patients.Apr 11, 2016

Selenium supplementation may reduce the risk of sepsis in preterm infants.Jan 01, 2003

The administration of intravenous vitamin C may lead to vasopressor sparing effects and a reduced need for mechanical ventilation in the critically ill.Dec 31, 2017

The efficacy of Omega-3 polyunsaturated fatty acids for severe burn patients.Jan 31, 2024

A large proportion of neonatal sepsis in developing countries could be effectively prevented using a synbiotic containing L. plantarum ATCC-202195.Jan 23, 2017

Acupuncture could adjust the immune function of sepsis patients, improve their immunological indicators and prognoses.Jun 30, 2015

Adjunctive homeopathic treatment has therapeutic value in patients with severe sepsis.Apr 01, 2005

Administration of melatonin as an adjuvant therapy in the treatment of neonatal sepsis is associated with improvement of clinical and laboratory outcomes.Oct 08, 2015

Association of opioid use in the week before death among patients with advanced lung cancer having sepsis.Dec 31, 2018

Association of vitamin D deficiency with an increased risk of late-onset neonatal sepsis.Dec 31, 2017

Biological effects of intravenous vitamin C on neutrophil extracellular traps and the endothelial glycocalyx in patients with sepsis-induced ARDS.Oct 20, 2022

Bovine lactoferrin supplementation prevents late-onset sepsis in very low-birth-weight neonates.Oct 07, 2009

Bovine lactoferrin supplementation protects against late-onset sepsis in infants.Sep 14, 2020

Coenzyme Q10 improves the survival and reduces inflammatory markers in septic patients.Dec 31, 2019

Consumption of vitamin D supplements might be helpful in decreasing the prevalence of infection, sepsis, and mortality caused by it.Dec 31, 2018

Current evidence indicates that lactoferrin could significantly reduce the incidence of necrotizing enterocolitis and late-onset sepsis.Jul 31, 2018

Early use of high-dose vitamin C is beneficial in treatment of sepsis.Jul 31, 2021

Effect of vitamin C administration on neutrophil apoptosis in septic patients after abdominal surgery.May 14, 2009

Enterobacter sakazakii (ES) is an emerging pathogen associated with the ingestion of contaminated reconstituted formula that causes necrotizing enterocolitis, sepsis, and meningitis in low-birth-weight preterm neonatal infants.Oct 01, 2008

High-dose ascorbic acid may be considered as an effective and safe adjuvant therapy in surgical critically ill patients with septic shock.Mar 31, 2016

Hydrocortisone, vitamin C and thiamine for the treatment of sepsis and septic shock following cardiac surgery.Nov 30, 2018

Immune function testing in sepsis patients receiving sodium selenite.Jul 31, 2019

Intravenous ascorbic acid infusion was safe and well tolerated in this study and may positively impact the extent of multiple organ failure.Jan 30, 2014

Intravenous vitamin C of ≥ 5 days was significantly associated with decreased hospital and 90-day mortality in sepsis patients.Jan 04, 2022

Introduction of probiotics for preterm infants in NZ has been associated with significant reductions in NEC and late onset sepsis.Dec 31, 2019

L-carnitine ameliorated inflammation, enhanced antioxidant defense, reduced mortality, and improved some clinical outcomes in critically ill patients with sepsis.Mar 05, 2024

Lactoferrin supplementation might reduce late-onset sepsis in very low birth weight infants.May 10, 2020

Level 1 and 2 evidence supports the use of thiamine, vitamin C, and vitamin D in COVID-like respiratory diseases, ARDS, and sepsis.Aug 22, 2020

Long-term lung protection of probiotics in children with sepsis and its mechanism.Nov 30, 2023

NAC plus antibiotics might reduce the 30-day mortality rate in ICU patients with CR-Kp and CR-Ab septic shock.Mar 07, 2021

Neonates with vitamin D deficiency/insufficiency are at higher risk for developing sepsis.Feb 12, 2020

Optimal vitamin D status may be important for innate immunity, especially in the setting of sepsis. Apr 23, 2009

Plasma CoQ10 levels could be increased in patients with severe sepsis or septic shock, with the administration of oral ubiquinol.Jun 30, 2015

Probiotics can be used to prevent necrotising enterocolitis and nosocomial infection in very low birth weight preterm infants.Mar 31, 2017

Probiotics supplementation resulted in significant decrease in proinflammatory and increase in anti-inflammatory cytokines in children with severe sepsis.Sep 30, 2018

Prophylactic oral administration of bovine lactoferrin reduces the incidence of nvasive fungal infection in preterm VLBW neonates.Dec 31, 2011

Serum coenzyme Q10 levels are decreased in critically-Ill septic patients.Jul 23, 2020

Severe depression and anxiety symptoms were associated with a moderately increased risk of bloodstream infection.Jun 18, 2018

Supplementation with propolis and melatonin may improve clinical outcomes by reducing inflammation.Feb 24, 2022

The administration of vitamin B 6 in the treatment of patients with sepsis attenuates renal injury,May 31, 2024

The association between vitamin D deficiency/lower 25(OH)D levels and sepsis was significant in children and neonates. Aug 26, 2019

The findings of this study confirm that extremely-low birth weight infants have an increase in cardiorespiratory events after vaccination.Aug 01, 2015

The statin drug atorvastatin is found in very high concentrations in intensive patients with sepsis.Apr 01, 2009

Therapeutic value of vitamin D as an adjuvant therapy in neonates with sepsis.Jun 25, 2019

Thiamine deficiency in sepsis may be associated with ICU-mortality.Jan 31, 2020

This study found an increase in adverse events after the routine immunization of extremely low-birth-weight infants in the NICU.May 31, 2015

This study shows that vitamin-D deficiency in term neonates may predispose them to late-onset sepsis.Apr 20, 2019

This trial demonstrated the safe induction of a stable ketogenic state in sepsis.Jul 09, 2024

Use of coconut oil helps in dermal maturity and better neurodevelopmental outcome of preterm newborns.Jun 28, 2019

Vitamin C and thiamine is associated with increased survival in septic ICU patients.Feb 06, 2020

Vitamin D deficiency and risk of acute lung injury in severe sepsis and severe trauma.Feb 23, 2014

Vitamin D deficiency is common in severe sepsis. Jan 31, 2017

Vitamin D is deficient in neonates with early onset sepsis and is associated with increased sepsis severity and mortality.Mar 14, 2020

Vitamin D status was inversely associated with risk of community-acquired pneumonia and sepsis hospitalization in a community-living adult population.Jun 09, 2014

Hydrocortisone and ascorbic acid synergistically prevent and repair lipopolysaccharide-induced pulmonary endothelial barrier dysfunction.Jan 10, 2017

Puerarin inhibited ferroptosis and inflammation of lung injury caused by sepsis.Dec 31, 2020

Zingerone could be a potential therapeutic agent for treatment of various severe vascular inflammatory diseases.Feb 28, 2018

Albiflorin alleviates sepsis-induced acute liver injury.Dec 31, 2023

Andrographolide attenuates sepsis-induced acute kidney injury.Feb 29, 2024

Carnosol alleviates sepsis-induced pulmonary endothelial barrier dysfunction.Feb 26, 2024

Molecular hydrogen protects mice against polymicrobial sepsis.Aug 31, 2015

Pterostilbene interferes with lipopolysaccharide-induced myocardial injury,Dec 31, 2021

Reversal of the pathophysiological responses to gram-negative sepsis by megadose vitamin C.Nov 24, 2020

Ganoderma lucidum polysaccharides protect against sepsis-induced cardiac dysfunction by activating SIRT1.Sep 23, 2021

Hydroxytyrosol ameliorates oxidative challenge and inflammatory response associated with lipopolysaccharide-mediated sepsis.Aug 24, 2020

Myricetin ameliorates sepsis-associated acute lung injury in a murine sepsis model.May 26, 2020

Oleuropein protects against lipopolysaccharide-induced sepsis and alleviates inflammatory responses in mice.Jul 24, 2020

Sepsis

View the Evidence:
480 Abstracts with Sepsis Research