Sexual Development: Dysfunctions and Abnormalities

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2 Substances Researched for Sexual Development: Dysfunctions and Abnormalities

Name	AC	CK	Focus
Soy	2	20
Curcumin	1	2

6 Problem Substances Researched for Sexual Development: Dysfunctions and Abnormalities

Name	AC	CK
Soy	2	20
Thimerosal	1	20
Bisphenol A	2	12
Mycoestrogens	1	10
Pesticides	1	2
Vinclozolin	1	2

Research Articles 10
Cumulative Knowledge Score 16
Overall Research Rating GOOD

View the Evidence:
10 Abstracts with Sexual Development: Dysfunctions and Abnormalities Research

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[+]

Thimerosal exposure is associated with increasing trends of premature puberty in 278,624 subjects from 1990-1996.Apr 01, 2010

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Pubmed Data : Indian J Med Res. 2010 Apr;131:500-7. PMID: 20424300

Article Published Date : Apr 01, 2010

Study Type : Meta Analysis

Additional Links

Diseases : Sexual Development: Dysfunctions and Abnormalities

Problem Substances : Thimerosal

Adverse Pharmacological Actions : Endocrine Disruptor

[+]

Early life soy exposure was associated with masculinized play behavior in girls at 42 months of age.Aug 03, 2011

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Pubmed Data : Environ Health Perspect. 2011 Aug 3. Epub 2011 Aug 3. PMID: 21813368

Article Published Date : Aug 03, 2011

Study Type : Human Study

Additional Links

Diseases : Sexual Development: Dysfunctions and Abnormalities

Problem Substances : Soy

[+]

Early-life soy exposure is associated with early onset menarche.Mar 01, 2012

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Pubmed Data : Paediatr Perinat Epidemiol. 2012 Mar ;26(2):163-75. Epub 2011 Dec 16. PMID: 22324503

Article Published Date : Mar 01, 2012

Study Type : Human Study

Additional Links

Substances : Soy

Diseases : Hormone Imbalances, Menarche: Early Onset, Sexual Development: Dysfunctions and Abnormalities

Problem Substances : Soy

Adverse Pharmacological Actions : Endocrine Disruptor

[+]

In utero BPA exposure adversely affect male genital development.Oct 01, 2011

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Pubmed Data : Birth Defects Res A Clin Mol Teratol. 2011 Oct ;91(10):867-72. Epub 2011 Aug 26. PMID: 21987463

Article Published Date : Oct 01, 2011

Study Type : Human Study

Additional Links

Diseases : Prenatal Chemical Exposures, Sexual Development: Dysfunctions and Abnormalities

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Endocrine Disruptor

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Mycoestrogens are found in 78.5% of Jersey girls and has been connected to endocrine disruption, e.g. delayed breast development.Oct 03, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Total Environ. 2011 Oct 3. Epub 2011 Oct 3. PMID: 21975003

Article Published Date : Oct 03, 2011

Study Type : Human Study

Additional Links

Diseases : Adolescent Diseases, Breast Development: Delayed, Sexual Development: Dysfunctions and Abnormalities

Problem Substances : Mycoestrogens

Adverse Pharmacological Actions : Endocrine Disruptor

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Soy intake is significantly negatively related to estrone and estradiol urinary excretion in boys and positively related to testosterone and 5-androstene-3β,17α diol urinary secretion in girls. Mar 22, 2011

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Pubmed Data : Am J Epidemiol. 2011 Mar 22. Epub 2011 Mar 22. PMID: 21427172

Article Published Date : Mar 22, 2011

Study Type : Human Study

Additional Links

Substances : Soy

Diseases : Sexual Development: Dysfunctions and Abnormalities

[+]

Combined exposure to endocrine disrupting pesticides impairs parturition, causes pup mortality and affects sexual differentiation in rats.Apr 01, 2010

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Pubmed Data : Int J Androl. 2010 Apr;33(2):434-42. PMID: 20487043

Article Published Date : Apr 01, 2010

Study Type : Animal Study

Additional Links

Diseases : Child Mortality , Sexual Development: Dysfunctions and Abnormalities

Problem Substances : Pesticides

Adverse Pharmacological Actions : Endocrine Disruptor

[+]

Curcumin has a protective effect on lindane induced reproductive toxicity in male Wistar rats.Apr 01, 2010

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Pubmed Data : Bull Environ Contam Toxicol. 2010 Apr;84(4):378-84. Epub 2010 Feb 25. PMID: 20182699

Article Published Date : Apr 01, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Infertility: Male, Pesticide Toxicity , Sexual Development: Dysfunctions and Abnormalities, Sperm Quality: Low

Additional Keywords : Chemical: Lindane

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Prepubertal exposure to bisphenol A affects the onset of puberty, ovarian weights, and estrous cycle in female mice.Jun 01, 2011

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Pubmed Data : Clin Exp Reprod Med. 2011 Jun ;38(2):75-81. Epub 2011 Jun 30. PMID: 22384422

Article Published Date : Jun 01, 2011

Study Type : Animal Study

Additional Links

Diseases : Infertility: Female, Sexual Development: Dysfunctions and Abnormalities

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Endocrine Disruptor

[+]

The fungicide Vinclozolin has been shown to have lasting transgenerational endocrine disrupting effects on male reproduction.Sep 01, 2009

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Pubmed Data : Semin Reprod Med. 2009 Sep;27(5):403-8. Epub 2009 Aug 26. PMID: 19711250

Article Published Date : Sep 01, 2009

Study Type : Animal Study

Additional Links

Diseases : Infertility: Male, Prenatal Chemical Exposures, Sexual Development: Dysfunctions and Abnormalities

Additional Keywords : Epigenetic Modification, Transgenerational Epigenetic Modification

Problem Substances : Vinclozolin

Adverse Pharmacological Actions : Endocrine Disruptor

Research Articles 10
Cumulative Knowledge Score 16
Overall Research Rating GOOD