Subarachnoid hemorrhage

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10 Substances Researched for Subarachnoid hemorrhage
NameACCKFocus
Magnesium110Locked
Ginkgo biloba24Locked
Curcumin23Locked
Apigenin12Locked
Arginine12Locked
Ginsenosides12Locked
Pomegranate12Locked
Pterostilbene12Locked
Resveratrol12Locked
EGCG (Epigallocatechin gallate)11Locked
3 Problem Substances Researched for Subarachnoid hemorrhage
NameACCKFocus
Aspirin 220Locked
Oral Contraceptives120Locked
Antiplatelet Drugs110Locked

View the Evidence:
44 Abstracts with Subarachnoid hemorrhage Research

[+]

Oral contraceptives have been shown to increase the risk of subarachnoid hemorrhage. Aug 01, 1998

Pubmed Data : Neurology. 1998 Aug;51(2):411-8. PMID: 9710012
Article Published Date : Aug 01, 1998
Study Type : Meta Analysis
Additional Links
Diseases : Subarachnoid hemorrhage
Problem Substances : Oral Contraceptives
[+]

Antiplatelet therapy does not appear to improve outcome in patients with cerebral aneurysm (subarachnoid hemorrhage).Jun 01, 2009

Pubmed Data : Stroke. 2009 Jun;40(6):1969-72. Epub 2009 Apr 23. PMID: 19390079
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Diseases : Cerebral Aneurysm, Subarachnoid hemorrhage
Problem Substances : Antiplatelet Drugs, Aspirin
[+]

Aspirin given after aneurysm treatment does not appreciably reduce the occurrence of delayed ischemic neurological deficit.Sep 01, 2006

Pubmed Data : Stroke. 2006 Sep;37(9):2326-30. Epub 2006 Aug 3. PMID: 16888270
Article Published Date : Sep 01, 2006
Study Type : Human Study
Additional Links
Diseases : Cerebral Aneurysm, Cerebral Ischemia, Subarachnoid hemorrhage
Problem Substances : Aspirin
[+]

Magnesium deficiency is associated with aneurysmal subarachnoid hemorrhage and resultant delayed ischemia. Feb 01, 2003

Pubmed Data : Neurosurgery. 2003 Feb;52(2):276-81; discussion 281-2. PMID: 12535355
Article Published Date : Feb 01, 2003
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Cerebral Aneurysm, Cerebral Ischemia, Magnesium Deficiency, Subarachnoid hemorrhage
[+]

Puerarin is an effective agent for the prophylaxis and treatment of the cerebral vasospasm in patients after aneurysm subarachnoid hemorrhage.Jan 31, 2012

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 Feb ;32(2):164-7. PMID: 22574584
Article Published Date : Jan 31, 2012
Study Type : Human Study
Additional Links
Substances : Puerarin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Allicin attenuates early brain injury after experimental subarachnoid hemorrhage.Feb 14, 2019

Pubmed Data : J Clin Neurosci. 2019 Feb 15. Epub 2019 Feb 15. PMID: 30773476
Article Published Date : Feb 14, 2019
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Apigenin could attenuate early brain injury after subarachnoid hemorrhage in rats by suppressing TLR4-mediated inflammation and protecting against BBB disruption.May 27, 2015

Pubmed Data : Int Immunopharmacol. 2015 May 28 ;28(1):79-87. Epub 2015 May 28. PMID: 26028151
Article Published Date : May 27, 2015
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Stroke: Attenuation/Recovery , Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Blood Brain Barrier
[+]

Astaxanthin mitigates subarachnoid hemorrhage injury.Jul 25, 2018

Pubmed Data : FASEB J. 2018 Jul 26:fj201800642RR. Epub 2018 Jul 26. PMID: 30048156
Article Published Date : Jul 25, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Astaxanthin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Astaxanthin reduces matrix metalloproteinase-9 expression and activity in the brain after experimental subarachnoid hemorrhage.Oct 21, 2015

Pubmed Data : Brain Res. 2015 Oct 22 ;1624:113-24. Epub 2015 Jul 23. PMID: 26210617
Article Published Date : Oct 21, 2015
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Malondialdehyde Down-regulation, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Astragaloside IV alleviates the brain damage induced by subarachnoid hemorrhage.Jun 29, 2020

Pubmed Data : Neurosci Lett. 2020 Jun 30 ;735:135227. Epub 2020 Jun 30. PMID: 32619654
Article Published Date : Jun 29, 2020
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Astragaloside IV may attenuate delayed cerebral vasospasm after subarachnoid hemorrhage.Jul 03, 2018

Pubmed Data : World Neurosurg. 2018 Jul 4. Epub 2018 Jul 4. PMID: 29981464
Article Published Date : Jul 03, 2018
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Biochanin A reduces inflammatory injury and neuronal apoptosis following subarachnoid hemorrhage.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Behav Neurol. 2018 ;2018:1960106. Epub 2018 Jun 3. PMID: 29971136
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Brain Inflammation , Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Caffeic acid phenethyl ester has a preventive effect on early brain injury after subarachnoid hemorrhage.Mar 17, 2020

Pubmed Data : World Neurosurg. 2020 Mar 18. Epub 2020 Mar 18. PMID: 32200016
Article Published Date : Mar 17, 2020
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester, Propolis: Bee
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Carnosic acid mitigates early brain injury after subarachnoid hemorrhage.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurosci. 2019 ;13:26. Epub 2019 Mar 5. PMID: 30890904
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Cinnamaldehyde could play a role in subarachnoid hemorrhage treatment.Aug 22, 2019

Pubmed Data : Metab Brain Dis. 2019 Aug 23. Epub 2019 Aug 23. PMID: 31444631
Article Published Date : Aug 22, 2019
Study Type : Animal Study
Additional Links
Substances : Cinnamaldehyde
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Curcumin attenuates vascular inflammation and cerebral vasospasm after subarachnoid hemorrhage in mice.Jan 01, 2009

Pubmed Data : Antioxid Redox Signal. 2009 Jan;11(1):35-45. PMID: 18752423
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Cerebral Vasospasm, Subarachnoid hemorrhage
Pharmacological Actions : NF-kappaB Inhibitor
[+]

Effect of gastrodin on early brain injury and neurological outcome after subarachnoid hemorrhage in rats.Jan 22, 2019

Pubmed Data : Neurosci Bull. 2019 Jan 23. Epub 2019 Jan 23. PMID: 30673960
Article Published Date : Jan 22, 2019
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Eucalyptol ameliorates early brain injury after subarachnoid haemorrhage.Nov 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2021 Dec ;59(1):114-120. PMID: 33550883
Article Published Date : Nov 30, 2021
Study Type : Animal Study
Additional Links
Substances : Eucalyptus
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Ginkgo biloba extract protects early brain injury after subarachnoid hemorrhage.Sep 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2020 Oct ;23(10):1340-1345. PMID: 33149868
Article Published Date : Sep 30, 2020
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Ginkgo biloba may have protective effect on secondary ischemic brain injury after experimental subarachnoid hemorrhage. Jan 01, 2003

Pubmed Data : Clin Hemorheol Microcirc. 2003;29(3-4):231-8. PMID: 14724346
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents, Vasodilator Agents
Additional Keywords : Plant Extracts
[+]

Ginkgo biloba may have protective effects on secondary cerebral ischemic injury after subarachnoid hemorrhage.Jan 01, 2009

Pubmed Data : Int J Neurosci. 2009;119(7):995-1005. PMID: 19466634
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Cerebral Ischemia, Subarachnoid hemorrhage
Pharmacological Actions : Vascular Endothelial Growth Factor A Enhancer
Additional Keywords : Plant Extracts
[+]

Ginseng reduces neurologic damage in subarachanoid hemorrhage. Mar 31, 2010

Pubmed Data : Curr Neurovasc Res. 2010 Mar 31. Epub 2010 Mar 31. PMID: 20353383
Article Published Date : Mar 31, 2010
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Cerebral Aneurysm, Stroke, Subarachnoid hemorrhage
[+]

Hesperidin might be useful in subarachnoid hemorrhage therapy.Nov 14, 2018

Pubmed Data : World Neurosurg. 2018 Nov 15. Epub 2018 Nov 15. PMID: 30448580
Article Published Date : Nov 14, 2018
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Hyperbaric oxygen therapy prevents subarachnoid hemorrhage-induced apoptosis and impaired contractility of the rabbit bladder.May 31, 2020

Pubmed Data : Neurourol Urodyn. 2020 Jun 1. Epub 2020 Jun 1. PMID: 32483860
Article Published Date : May 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Subarachnoid hemorrhage
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Apoptotic
[+]

L-arginine improves cerebral blood perfusion and vasomotion of microvessels following subarachnoid hemorrhage in rats.Jan 01, 2003

Pubmed Data : Clin Hemorheol Microcirc. 2003;29(3-4):391-400. PMID: 14724366
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Cerebral Ischemia, Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Naringin alleviates early brain injury after experimental subarachnoid hemorrhage.Jun 30, 2017

Pubmed Data : Brain Res Bull. 2017 Jul ;133:42-50. Epub 2016 Dec 21. PMID: 28011192
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Oxidative Stress, Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Oleanolic acid exerts neuroprotective effects in subarachnoid hemorrhage rats through SIRT1-mediated HMGB1 deacetylation.Feb 14, 2021

Pubmed Data : Eur J Pharmacol. 2021 Feb 15 ;893:173811. Epub 2020 Dec 24. PMID: 33345851
Article Published Date : Feb 14, 2021
Study Type : Animal Study
Additional Links
Substances : Oleanolic acid
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Paeoniflorin attenuates early brain injury through reducing oxidative stress and neuronal apoptosis after subarachnoid hemorrhage.Apr 02, 2020

Pubmed Data : Metab Brain Dis. 2020 Apr 3. Epub 2020 Apr 3. PMID: 32246322
Article Published Date : Apr 02, 2020
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
[+]

Pomegranate was shown to have a vasospasm attenuating effect on the basilar artery in the rabbit SAH model.Aug 09, 2016

Pubmed Data : J Neurol Surg A Cent Eur Neurosurg. 2016 Aug 10. Epub 2016 Aug 10. PMID: 27509316
Article Published Date : Aug 09, 2016
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Subarachnoid hemorrhage
[+]

Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury.Oct 31, 2018

Pubmed Data : Acta Histochem. 2018 Nov 1. Epub 2018 Nov 1. PMID: 30392635
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Pterostilbene attenuates early brain injury following subarachnoid hemorrhage.Sep 23, 2016

Pubmed Data : Mol Neurobiol. 2016 Sep 24. Epub 2016 Sep 24. PMID: 27665283
Article Published Date : Sep 23, 2016
Study Type : Animal Study
Additional Links
Substances : Pterostilbene
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants
[+]

Puerarin can provide potential neuroprotection from the subarachnoid hemorrhage damages.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:726-733. Epub 2018 Nov 5. PMID: 30551525
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Resveratrol treatment could alleviate early brain injury after subarachnoid haemorrhage.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 ;17(8). Epub 2016 Aug 12. PMID: 27529233
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Aneurysmal subarachnoid hemorrhage (SAH), Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Salvianolic acid A attenuates early brain injury after subarachnoid hemorrhage.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2017 ;9(12):5643-5652. Epub 2017 Dec 15. PMID: 29312516
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Red Sage
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Neuroprotective Agents, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tetramethylpyrazine nitrone reduces oxidative stress to alleviate cerebral vasospasm in experimental subarachnoid hemorrhage models.Aug 31, 2019

Pubmed Data : Neuromolecular Med. 2019 Sep ;21(3):262-274. Epub 2019 May 27. PMID: 31134485
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Tetramethylpyrazine protects against early brain injury in a model of subarachnoid hemorrhage.Jul 31, 2018

Pubmed Data : Neurochem Res. 2018 Aug ;43(8):1650-1659. Epub 2018 Jun 27. PMID: 29951731
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Thymoquinone ameliorates delayed cerebral injury and cerebral vasospasm secondary to experimental subarachnoid haemorrhage.Nov 29, 2020

Pubmed Data : Neurol Neurochir Pol. 2020 Nov 30. Epub 2020 Nov 30. PMID: 33252137
Article Published Date : Nov 29, 2020
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

β-caryophyllene liposomes attenuate neurovascular unit damage after subarachnoid hemorrhage.May 21, 2020

Pubmed Data : Neurochem Res. 2020 May 22. Epub 2020 May 22. PMID: 32444923
Article Published Date : May 21, 2020
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Berberine ameliorates subarachnoid hemorrhage injury. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:1073. Epub 2020 Jul 10. PMID: 32754040
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Curcumin inhibits neuronal apoptosis and alleviates oxidative stress and inflammation in neurons subjected to Oxyhemoglobin.Nov 09, 2015

Pubmed Data : Brain Res Bull. 2015 Nov 10 ;120:34-40. Epub 2015 Nov 10. PMID: 26551062
Article Published Date : Nov 09, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

EGCG can be regarded as a new pharmacological agent that targets both mitochondria and altered autophagy in subarachnoid haemorrhage therapy.Jan 06, 2016

Pubmed Data : Mol Neurobiol. 2016 Jan 7. Epub 2016 Jan 7. PMID: 26742518
Article Published Date : Jan 06, 2016
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Mitochondrial Dysfunction , Subarachnoid hemorrhage
[+]

Fucoxanthin provided protection against subarachnoid hemorrhage-induced oxidative insults.Nov 30, 2020

Pubmed Data : Mol Neurobiol. 2020 Dec ;57(12):5286-5298. Epub 2020 Sep 2. PMID: 32876840
Article Published Date : Nov 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Melatonin provided protection against brain injury post-SAH subarachnoid hemorrhage.Sep 12, 2018

Pubmed Data : Med Sci Monit. 2018 Sep 13 ;24:6422-6430. Epub 2018 Sep 13. PMID: 30210141
Article Published Date : Sep 12, 2018
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

This review discusses the potential effects of melatonin on cerebral autoregulation following subarachnoid hemorrhage.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2018 ;9:1146. Epub 2018 Aug 17. PMID: 30174621
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Antioxidants, Neuroprotective Agents

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