Subarachnoid hemorrhage

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43 Substances Researched for Subarachnoid hemorrhage
NameACCKFocus
Resveratrol324Locked
Puerarin314Locked
Magnesium110Locked
Astaxanthin48Locked
Hydrogen Water48Locked
Ginkgo biloba36Locked
Astragaloside24Locked
Ligustrazine24Locked
Melatonin34Locked
Pterostilbene24Locked
Andrographolide13Locked
Curcumin23Locked
Flavonoids23Locked
Allicin12Locked
Apigenin12Locked
Arginine12Locked
Beta-Caryophyllene12Locked
Biochanin A12Locked
Caffeic acid phenethyl ester12Locked
Carnosic Acid12Locked
Cinnamaldehyde12Locked
Citrus naringin12Locked
Eucalyptus12Locked
Gastrodin12Locked
Gingerol 12Locked
Ginsenosides12Locked
Hesperidin12Locked
Hydrogen: Molecular12Locked
Luteolin12Locked
Oleanolic acid12Locked
Paeoniflorin12Locked
Piceatannol 12Locked
Pomegranate12Locked
Propolis: Bee12Locked
Red Sage12Locked
Salvia miltiorrhiza12Locked
Tanshinone IIA12Locked
Thymoquinone12Locked
Urolithin A 12Locked
Berberine11Locked
Cannabidiol11Locked
EGCG (Epigallocatechin gallate)11Locked
Fucoxanthin 11Locked
3 Problem Substances Researched for Subarachnoid hemorrhage
NameACCKFocus
Aspirin 220Locked
Oral Contraceptives120Locked
Antiplatelet Drugs110Locked
2 Therapeutic Actions Researched for Subarachnoid hemorrhage
NameACCKFocus
Electroacupuncture12Locked
Hyperbaric Treatment12Locked

View the Evidence:
72 Abstracts with Subarachnoid hemorrhage Research

[+]

Efficacy of resveratrol in experimental subarachnoid hemorrhage animal models.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:905208. Epub 2022 Jun 29. PMID: 35847035
Article Published Date : Dec 31, 2021
Study Type : Meta Analysis
Additional Links
Substances : Resveratrol
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Oral contraceptives have been shown to increase the risk of subarachnoid hemorrhage. Aug 01, 1998

Pubmed Data : Neurology. 1998 Aug;51(2):411-8. PMID: 9710012
Article Published Date : Aug 01, 1998
Study Type : Meta Analysis
Additional Links
Diseases : Subarachnoid hemorrhage
Problem Substances : Oral Contraceptives
[+]

Antiplatelet therapy does not appear to improve outcome in patients with cerebral aneurysm (subarachnoid hemorrhage).Jun 01, 2009

Pubmed Data : Stroke. 2009 Jun;40(6):1969-72. Epub 2009 Apr 23. PMID: 19390079
Article Published Date : Jun 01, 2009
Study Type : Human Study
Additional Links
Diseases : Cerebral Aneurysm, Subarachnoid hemorrhage
Problem Substances : Antiplatelet Drugs, Aspirin
[+]

Aspirin given after aneurysm treatment does not appreciably reduce the occurrence of delayed ischemic neurological deficit.Sep 01, 2006

Pubmed Data : Stroke. 2006 Sep;37(9):2326-30. Epub 2006 Aug 3. PMID: 16888270
Article Published Date : Sep 01, 2006
Study Type : Human Study
Additional Links
Diseases : Cerebral Aneurysm, Cerebral Ischemia, Subarachnoid hemorrhage
Problem Substances : Aspirin
[+]

Magnesium deficiency is associated with aneurysmal subarachnoid hemorrhage and resultant delayed ischemia. Feb 01, 2003

Pubmed Data : Neurosurgery. 2003 Feb;52(2):276-81; discussion 281-2. PMID: 12535355
Article Published Date : Feb 01, 2003
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Cerebral Aneurysm, Cerebral Ischemia, Magnesium Deficiency, Subarachnoid hemorrhage
[+]

Puerarin is an effective agent for the prophylaxis and treatment of the cerebral vasospasm in patients after aneurysm subarachnoid hemorrhage.Jan 31, 2012

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 Feb ;32(2):164-7. PMID: 22574584
Article Published Date : Jan 31, 2012
Study Type : Human Study
Additional Links
Substances : Puerarin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Andrographolide alleviated blood-brain barrier disruption, neuronal apoptosis, and oxidative stress in subarachnoid hemorrhage.Mar 18, 2022

Pubmed Data : Neurotox Res. 2022 Mar 19. Epub 2022 Mar 19. PMID: 35305248
Article Published Date : Mar 18, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Andrographolide
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
[+]

Nrf2 activation by neferine mitigates microglial neuroinflammation after subarachnoid hemorrhage.Mar 29, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int Immunopharmacol. 2024 Mar 30 ;130:111693. Epub 2024 Mar 1. PMID: 38428144
Article Published Date : Mar 29, 2024
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Lotus
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation
[+]

6-gingerol attenuates subarachnoid hemorrhage-induced early brain injury.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2022 ;13:882121. Epub 2022 Aug 25. PMID: 36091803
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Gingerol
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Allicin attenuates early brain injury after experimental subarachnoid hemorrhage.Feb 14, 2019

Pubmed Data : J Clin Neurosci. 2019 Feb 15. Epub 2019 Feb 15. PMID: 30773476
Article Published Date : Feb 14, 2019
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Alpha-lipoic acid ameliorates early brain injury after subarachnoid hemorrhage.Mar 05, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuroreport. 2024 Mar 6 ;35(4):250-257. Epub 2024 Jan 15. PMID: 38305103
Article Published Date : Mar 05, 2024
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Apigenin could attenuate early brain injury after subarachnoid hemorrhage in rats by suppressing TLR4-mediated inflammation and protecting against BBB disruption.May 27, 2015

Pubmed Data : Int Immunopharmacol. 2015 May 28 ;28(1):79-87. Epub 2015 May 28. PMID: 26028151
Article Published Date : May 27, 2015
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Stroke: Attenuation/Recovery , Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Blood Brain Barrier
[+]

Astaxanthin mitigates subarachnoid hemorrhage injury.Jul 25, 2018

Pubmed Data : FASEB J. 2018 Jul 26:fj201800642RR. Epub 2018 Jul 26. PMID: 30048156
Article Published Date : Jul 25, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Astaxanthin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Astaxanthin reduces matrix metalloproteinase-9 expression and activity in the brain after experimental subarachnoid hemorrhage.Oct 21, 2015

Pubmed Data : Brain Res. 2015 Oct 22 ;1624:113-24. Epub 2015 Jul 23. PMID: 26210617
Article Published Date : Oct 21, 2015
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Malondialdehyde Down-regulation, Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]

Astragaloside IV alleviates the brain damage induced by subarachnoid hemorrhage.Jun 29, 2020

Pubmed Data : Neurosci Lett. 2020 Jun 30 ;735:135227. Epub 2020 Jun 30. PMID: 32619654
Article Published Date : Jun 29, 2020
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Astragaloside IV may attenuate delayed cerebral vasospasm after subarachnoid hemorrhage.Jul 03, 2018

Pubmed Data : World Neurosurg. 2018 Jul 4. Epub 2018 Jul 4. PMID: 29981464
Article Published Date : Jul 03, 2018
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Baicalin suppresses autophagy-dependent ferroptosis in early brain injury after subarachnoid hemorrhage.Jan 11, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bioengineered. 2021 12 ;12(1):7794-7804. PMID: 34704542
Article Published Date : Jan 11, 2021
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Beneficial effect of hydrogen-rich saline on cerebral vasospasm after experimental subarachnoid hemorrhage in rats.Jul 31, 2012

Pubmed Data : J Neurosci Res. 2012 Aug ;90(8):1670-80. Epub 2012 May 15. PMID: 22589232
Article Published Date : Jul 31, 2012
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Lipid Peroxidation, Oxidative Stress, Subarachnoid hemorrhage
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Biochanin A reduces inflammatory injury and neuronal apoptosis following subarachnoid hemorrhage.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Behav Neurol. 2018 ;2018:1960106. Epub 2018 Jun 3. PMID: 29971136
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Brain Inflammation , Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Caffeic acid phenethyl ester has a preventive effect on early brain injury after subarachnoid hemorrhage.Mar 17, 2020

Pubmed Data : World Neurosurg. 2020 Mar 18. Epub 2020 Mar 18. PMID: 32200016
Article Published Date : Mar 17, 2020
Study Type : Animal Study
Additional Links
Substances : Caffeic acid phenethyl ester, Propolis: Bee
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Carnosic acid mitigates early brain injury after subarachnoid hemorrhage.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurosci. 2019 ;13:26. Epub 2019 Mar 5. PMID: 30890904
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Cinnamaldehyde could play a role in subarachnoid hemorrhage treatment.Aug 22, 2019

Pubmed Data : Metab Brain Dis. 2019 Aug 23. Epub 2019 Aug 23. PMID: 31444631
Article Published Date : Aug 22, 2019
Study Type : Animal Study
Additional Links
Substances : Cinnamaldehyde
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Curcumin attenuates vascular inflammation and cerebral vasospasm after subarachnoid hemorrhage in mice.Jan 01, 2009

Pubmed Data : Antioxid Redox Signal. 2009 Jan;11(1):35-45. PMID: 18752423
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Cerebral Vasospasm, Subarachnoid hemorrhage
Pharmacological Actions : NF-kappaB Inhibitor
[+]

Effect of astaxanthin on neuron damage, inflammatory factors expressions and oxidative stress in mice with subarachnoid hemorrhage.Dec 31, 2020

Pubmed Data : Am J Transl Res. 2021 ;13(11):13043-13050. Epub 2021 Nov 15. PMID: 34956522
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Bcl-2 protein down-regulation, Interleukin-17 downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effect of gastrodin on early brain injury and neurological outcome after subarachnoid hemorrhage in rats.Jan 22, 2019

Pubmed Data : Neurosci Bull. 2019 Jan 23. Epub 2019 Jan 23. PMID: 30673960
Article Published Date : Jan 22, 2019
Study Type : Animal Study
Additional Links
Substances : Gastrodin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Electroacupuncture enhances cerebral blood perfusion by inhibiting HIF-1α in rat subarachnoid hemorrhage.Sep 14, 2024

Pubmed Data : Brain Res. 2024 Sep 15 ;1839:149010. Epub 2024 May 17. PMID: 38763503
Article Published Date : Sep 14, 2024
Study Type : Animal Study
Additional Links
Diseases : Subarachnoid hemorrhage
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Neuroprotective Agents
[+]

Electroacupuncture treatment is a potential therapy for the treatment of cognitive deficit after subarachnoid hemorrhage.Nov 15, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metab Brain Dis. 2022 Nov 16. Epub 2022 Nov 16. PMID: 36383326
Article Published Date : Nov 15, 2022
Study Type : Animal Study
Additional Links
Diseases : Cognitive Decline/Dysfunction, Subarachnoid hemorrhage
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Remyelination
[+]

Eucalyptol ameliorates early brain injury after subarachnoid haemorrhage.Nov 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2021 Dec ;59(1):114-120. PMID: 33550883
Article Published Date : Nov 30, 2021
Study Type : Animal Study
Additional Links
Substances : Eucalyptus
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Ginkgo biloba extract protects early brain injury after subarachnoid hemorrhage.Sep 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2020 Oct ;23(10):1340-1345. PMID: 33149868
Article Published Date : Sep 30, 2020
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Ginkgo biloba may have protective effect on secondary ischemic brain injury after experimental subarachnoid hemorrhage. Jan 01, 2003

Pubmed Data : Clin Hemorheol Microcirc. 2003;29(3-4):231-8. PMID: 14724346
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents, Vasodilator Agents
Additional Keywords : Plant Extracts
[+]

Ginkgo biloba may have protective effects on secondary cerebral ischemic injury after subarachnoid hemorrhage.Jan 01, 2009

Pubmed Data : Int J Neurosci. 2009;119(7):995-1005. PMID: 19466634
Article Published Date : Jan 01, 2009
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Cerebral Ischemia, Subarachnoid hemorrhage
Pharmacological Actions : Vascular Endothelial Growth Factor A Enhancer
Additional Keywords : Plant Extracts
[+]

Ginseng reduces neurologic damage in subarachanoid hemorrhage. Mar 31, 2010

Pubmed Data : Curr Neurovasc Res. 2010 Mar 31. Epub 2010 Mar 31. PMID: 20353383
Article Published Date : Mar 31, 2010
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Cerebral Aneurysm, Stroke, Subarachnoid hemorrhage
[+]

Hesperidin might be useful in subarachnoid hemorrhage therapy.Nov 14, 2018

Pubmed Data : World Neurosurg. 2018 Nov 15. Epub 2018 Nov 15. PMID: 30448580
Article Published Date : Nov 14, 2018
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Huperzine A ameliorates neurological deficits after spontaneous subarachnoid hemorrhage.Apr 24, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Biochim Biophys Sin (Shanghai). 2024 Apr 25 ;56(4):645-656. PMID: 38529553
Article Published Date : Apr 24, 2024
Study Type : Animal Study
Additional Links
Substances : Huperzine
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.Mar 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Crit Care Med. 2012 Apr ;40(4):1291-6. PMID: 22336722
Article Published Date : Mar 31, 2012
Study Type : Animal Study
Additional Links
Substances : Hydrogen: Molecular
Diseases : Lipid Peroxidation, Oxidative Stress, Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Malondialdehyde Down-regulation
[+]

Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage.May 14, 2012

Pubmed Data : BMC Neurosci. 2012 May 15 ;13:47. Epub 2012 May 15. PMID: 22587664
Article Published Date : May 14, 2012
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Oxidative Stress, Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Antioxidants
[+]

Hydrogen-rich saline attenuated subarachnoid hemorrhage-induced early brain injury.Jun 30, 2016

Pubmed Data : Mol Neurobiol. 2016 Jul ;53(5):3462-3476. Epub 2015 Jun 20. PMID: 26091790
Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Inflammation, Lipid Peroxidation, Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Hyperbaric oxygen therapy prevents subarachnoid hemorrhage-induced apoptosis and impaired contractility of the rabbit bladder.May 31, 2020

Pubmed Data : Neurourol Urodyn. 2020 Jun 1. Epub 2020 Jun 1. PMID: 32483860
Article Published Date : May 31, 2020
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Subarachnoid hemorrhage
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Apoptotic
[+]

Isoliquiritigenin attenuates neuroinflammation after subarachnoid hemorrhage.Jan 31, 2024

Pubmed Data : Chem Biol Drug Des. 2024 Feb ;103(2):e14436. PMID: 38395608
Article Published Date : Jan 31, 2024
Study Type : Animal Study
Additional Links
Substances : Isoliquiritigenin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

L-arginine improves cerebral blood perfusion and vasomotion of microvessels following subarachnoid hemorrhage in rats.Jan 01, 2003

Pubmed Data : Clin Hemorheol Microcirc. 2003;29(3-4):391-400. PMID: 14724366
Article Published Date : Jan 01, 2003
Study Type : Animal Study
Additional Links
Substances : Arginine
Diseases : Cerebral Ischemia, Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Luteolin confers cerebroprotection after subarachnoid hemorrhage by suppression of NLPR3 inflammasome activation.Dec 31, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2021 ;2021:5838101. Epub 2021 Nov 5. PMID: 34777689
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Luteolin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, Nrf2 activation
[+]

Melatonin alleviates early brain injury by inhibiting the NRF2-mediated ferroptosis pathway after subarachnoid hemorrhage.Oct 31, 2023

Pubmed Data : Free Radic Biol Med. 2023 Nov 1 ;208:555-570. Epub 2023 Sep 17. PMID: 37717795
Article Published Date : Oct 31, 2023
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Naringin alleviates early brain injury after experimental subarachnoid hemorrhage.Jun 30, 2017

Pubmed Data : Brain Res Bull. 2017 Jul ;133:42-50. Epub 2016 Dec 21. PMID: 28011192
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Oxidative Stress, Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Oleanolic acid exerts neuroprotective effects in subarachnoid hemorrhage rats through SIRT1-mediated HMGB1 deacetylation.Feb 14, 2021

Pubmed Data : Eur J Pharmacol. 2021 Feb 15 ;893:173811. Epub 2020 Dec 24. PMID: 33345851
Article Published Date : Feb 14, 2021
Study Type : Animal Study
Additional Links
Substances : Oleanolic acid
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Paeoniflorin attenuates early brain injury through reducing oxidative stress and neuronal apoptosis after subarachnoid hemorrhage.Apr 02, 2020

Pubmed Data : Metab Brain Dis. 2020 Apr 3. Epub 2020 Apr 3. PMID: 32246322
Article Published Date : Apr 02, 2020
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
[+]

Piceatannol would be a potential therapeutic agent for alleviating olfactory bulb injury after subarachnoid hemorrhage.Jun 30, 2023

Pubmed Data : Mol Neurobiol. 2023 Jul ;60(7):3695-3706. Epub 2023 Mar 18. PMID: 36933146
Article Published Date : Jun 30, 2023
Study Type : Animal Study
Additional Links
Substances : Piceatannol
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Pomegranate was shown to have a vasospasm attenuating effect on the basilar artery in the rabbit SAH model.Aug 09, 2016

Pubmed Data : J Neurol Surg A Cent Eur Neurosurg. 2016 Aug 10. Epub 2016 Aug 10. PMID: 27509316
Article Published Date : Aug 09, 2016
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Subarachnoid hemorrhage
[+]

Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury.Oct 31, 2018

Pubmed Data : Acta Histochem. 2018 Nov 1. Epub 2018 Nov 1. PMID: 30392635
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Pterostilbene attenuates early brain injury following subarachnoid hemorrhage.Sep 23, 2016

Pubmed Data : Mol Neurobiol. 2016 Sep 24. Epub 2016 Sep 24. PMID: 27665283
Article Published Date : Sep 23, 2016
Study Type : Animal Study
Additional Links
Substances : Pterostilbene
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants
[+]

Pterostilbene attenuates subarachnoid hemorrhage-induced brain injury.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:3550204. Epub 2022 Nov 30. PMID: 36506933
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Pterostilbene
Diseases : Oxidative Stress, Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Puerarin attenuates oxidative stress and ferroptosis via AMPK/PGC1α/Nrf2 pathway after subarachnoid hemorrhage.Jun 26, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antioxidants (Basel). 2022 Jun 27 ;11(7). Epub 2022 Jun 27. PMID: 35883750
Article Published Date : Jun 26, 2022
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Puerarin can provide potential neuroprotection from the subarachnoid hemorrhage damages.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:726-733. Epub 2018 Nov 5. PMID: 30551525
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Resveratrol treatment could alleviate early brain injury after subarachnoid haemorrhage.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 ;17(8). Epub 2016 Aug 12. PMID: 27529233
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Aneurysmal subarachnoid hemorrhage (SAH), Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Salvianolic acid A attenuates early brain injury after subarachnoid hemorrhage.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2017 ;9(12):5643-5652. Epub 2017 Dec 15. PMID: 29312516
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Red Sage
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Neuroprotective Agents, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid hemorrhage.Dec 31, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2023 ;14:1159958. Epub 2023 Jul 26. PMID: 37564636
Article Published Date : Dec 31, 2022
Study Type : Animal Study
Additional Links
Substances : Salvia miltiorrhiza
Diseases : Brain Inflammation , Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, SIRT1 Activator
[+]

Sinomenine protects against early brain injury.Apr 24, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Brain Sci. 2023 Apr 25 ;13(5). Epub 2023 Apr 25. PMID: 37239188
Article Published Date : Apr 24, 2023
Study Type : Animal Study
Additional Links
Substances : Sinomenine
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Nrf2 activation
[+]

SIRT1 activation by resveratrol promotes long-term functional recovery after subarachnoid hemorrhage.May 31, 2023

Pubmed Data : Neurocrit Care. 2023 Jun ;38(3):622-632. Epub 2022 Oct 12. PMID: 36224490
Article Published Date : May 31, 2023
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents, SIRT1 Activator
[+]

Tanshinone IIA alleviates early brain injury after subarachnoid hemorrhage.Jan 25, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2024 Jan 26 ;47(1):279-291. Epub 2023 Dec 6. PMID: 38057100
Article Published Date : Jan 25, 2024
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Tetramethylpyrazine nitrone reduces oxidative stress to alleviate cerebral vasospasm in experimental subarachnoid hemorrhage models.Aug 31, 2019

Pubmed Data : Neuromolecular Med. 2019 Sep ;21(3):262-274. Epub 2019 May 27. PMID: 31134485
Article Published Date : Aug 31, 2019
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Tetramethylpyrazine protects against early brain injury in a model of subarachnoid hemorrhage.Jul 31, 2018

Pubmed Data : Neurochem Res. 2018 Aug ;43(8):1650-1659. Epub 2018 Jun 27. PMID: 29951731
Article Published Date : Jul 31, 2018
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

The current study shows that hydrogen treatment alleviates early brain injury.Nov 30, 2013

Pubmed Data : J Neurosci Res. 2013 Dec ;91(12):1599-608. Epub 2013 Sep 16. PMID: 24105634
Article Published Date : Nov 30, 2013
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Thymoquinone ameliorates delayed cerebral injury and cerebral vasospasm secondary to experimental subarachnoid haemorrhage.Nov 29, 2020

Pubmed Data : Neurol Neurochir Pol. 2020 Nov 30. Epub 2020 Nov 30. PMID: 33252137
Article Published Date : Nov 29, 2020
Study Type : Animal Study
Additional Links
Substances : Thymoquinone
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Urolithin A alleviates early brain injury after subarachnoid hemorrhage.Aug 17, 2023

Pubmed Data : Neurochirurgie. 2023 Aug 18 ;69(5):101480. Epub 2023 Aug 18. PMID: 37598622
Article Published Date : Aug 17, 2023
Study Type : Animal Study
Additional Links
Substances : Urolithin A
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

β-caryophyllene liposomes attenuate neurovascular unit damage after subarachnoid hemorrhage.May 21, 2020

Pubmed Data : Neurochem Res. 2020 May 22. Epub 2020 May 22. PMID: 32444923
Article Published Date : May 21, 2020
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Berberine ameliorates subarachnoid hemorrhage injury. Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:1073. Epub 2020 Jul 10. PMID: 32754040
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
[+]

Cannabidiol's multifactorial mechanisms has therapeutic potential for aneurysmal subarachnoid hemorrhage.Sep 14, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Transl Stroke Res. 2022 Sep 15. Epub 2022 Sep 15. PMID: 36109476
Article Published Date : Sep 14, 2022
Study Type : Review
Additional Links
Substances : Cannabidiol
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
[+]

Curcumin inhibits neuronal apoptosis and alleviates oxidative stress and inflammation in neurons subjected to Oxyhemoglobin.Nov 09, 2015

Pubmed Data : Brain Res Bull. 2015 Nov 10 ;120:34-40. Epub 2015 Nov 10. PMID: 26551062
Article Published Date : Nov 09, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

EGCG can be regarded as a new pharmacological agent that targets both mitochondria and altered autophagy in subarachnoid haemorrhage therapy.Jan 06, 2016

Pubmed Data : Mol Neurobiol. 2016 Jan 7. Epub 2016 Jan 7. PMID: 26742518
Article Published Date : Jan 06, 2016
Study Type : In Vitro Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Mitochondrial Dysfunction , Subarachnoid hemorrhage
[+]

Eriocitrin alleviates inflammation and oxidative stress in subarachnoid hemorrhage.Nov 30, 2023

Pubmed Data : Discov Med. 2023 Dec ;35(179):1134-1146. PMID: 38058079
Article Published Date : Nov 30, 2023
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Inflammation, Oxidative Stress, Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, NF-kappaB Inhibitor, Superoxide Dismutase Up-regulation
[+]

Fucoxanthin provided protection against subarachnoid hemorrhage-induced oxidative insults.Nov 30, 2020

Pubmed Data : Mol Neurobiol. 2020 Dec ;57(12):5286-5298. Epub 2020 Sep 2. PMID: 32876840
Article Published Date : Nov 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Fucoxanthin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

Melatonin provided protection against brain injury post-SAH subarachnoid hemorrhage.Sep 12, 2018

Pubmed Data : Med Sci Monit. 2018 Sep 13 ;24:6422-6430. Epub 2018 Sep 13. PMID: 30210141
Article Published Date : Sep 12, 2018
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

This review discusses the potential effects of melatonin on cerebral autoregulation following subarachnoid hemorrhage.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Physiol. 2018 ;9:1146. Epub 2018 Aug 17. PMID: 30174621
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Antioxidants, Neuroprotective Agents

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