Traumatic Brain Injury

Views 961
Jump to
Abstracts Focused Research Topics
Your Token Count0

Sign in to Purchase/Download Documents

Sign in / Register

Focus Your Research

Click any topic below to filter + focus research
23 Substances Researched for Traumatic Brain Injury
NameACCKFocus
Acetyl-l-carnitine110Locked
Alpha-Lipoic Acid110Locked
Fish Oil110Locked
Ginkgo biloba110Locked
Huperzine110Locked
Multivitamin110Locked
NAC (N-acetyl-L-cysteine)110Locked
Vinpocetine110Locked
Resveratrol34Locked
Sulforaphane24Locked
Thymoquinone23Locked
Cannabinoids 12Locked
Choline12Locked
Coenzyme Q1012Locked
Crocin12Locked
Ellagic Acid12Locked
Endocannabinoids12Locked
Genistein12Locked
Melatonin12Locked
Vitamin C12Locked
Vitamin E: alpha tocopherol12Locked
Nigella sativa (aka Black Seed)11Locked
Pterostilbene11Locked
1 Problem Substances Researched for Traumatic Brain Injury
NameACCKFocus
Clopidogrel110Locked
4 Therapeutic Actions Researched for Traumatic Brain Injury
NameACCKFocus
Light-Emitting Diodes (LEDs) Therapy110Locked
Acupuncture26Locked
Hyperbaric Treatment23Locked
Laser Treatment: Low-Level11Locked

View the Evidence:
72 Abstracts with Traumatic Brain Injury Research

[+]

Acupuncture can be an effective treatment for patients unconscious following traumatic brain injury.Feb 20, 2020

Pubmed Data : Altern Ther Health Med. 2020 Feb 21. Epub 2020 Feb 21. PMID: 32088667
Article Published Date : Feb 20, 2020
Study Type : Meta Analysis, Review
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Acupuncture
Pharmacological Actions : Neuroprotective Agents
[+]

Patients undergoing hyperbaric therapy achieved significant improvement in the GCS and GOS with a lower overall mortality.Apr 30, 2016

Pubmed Data : Neurol Sci. 2016 May ;37(5):693-701. Epub 2016 Jan 8. PMID: 26746238
Article Published Date : Apr 30, 2016
Study Type : Meta Analysis
Additional Links
Diseases : Traumatic Brain Injury
Additional Keywords : Significant Treatment Outcome
[+]

A nutrient combination improves cognitive function in head injuried former NFL players. Jan 01, 2011

Pubmed Data : J Psychoactive Drugs. 2011 Jan-Mar;43(1):1-5. PMID: 21615001
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Acetyl-l-carnitine, Alpha-Lipoic Acid, Fish Oil, Ginkgo biloba, Huperzine, Multivitamin, NAC (N-acetyl-L-cysteine), Vinpocetine
Diseases : Brain Damage, Head Injuries, Traumatic Brain Injury
Pharmacological Actions : Neurorestorative
[+]

Acupuncture treatment increased the cortico spinal tract activity of patients with chronic chronic disorders of consciousness after severe TBI.Oct 31, 2016

Pubmed Data : J Altern Complement Med. 2016 Nov ;22(11):887-894. Epub 2016 Sep 23. PMID: 27662495
Article Published Date : Oct 31, 2016
Study Type : Human Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Acupuncture
[+]

HBOT was significantly effective for veterans with mild to moderate traumatic brain injury with persistent post-concussion syndrome and PTSD.Jun 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Gas Res. 2017 Jul-Sep;7(3):156-174. Epub 2017 Oct 17. PMID: 29152209
Article Published Date : Jun 30, 2017
Study Type : Human Study
Additional Links
Diseases : Brain Concussion, Post-Traumatic Stress Disorders (PTSD), Suicidal Ideation, Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Additional Keywords : Medication Reduction, Significant Treatment Outcome
[+]

Hyperbaric oxygen therapy can induce angiogenesis and regeneration of nerve fibers in traumatic brain injury patients.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Hum Neurosci. 2017 ;11:508. Epub 2017 Oct 19. PMID: 29097988
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Regenerative
[+]

Hyperbaric oxygen therapy for mild traumatic brain injury persistent postconcussion syndrome.Dec 31, 2019

Pubmed Data : Med Gas Res. 2020 Jan-Mar;10(1):8-20. PMID: 32189664
Article Published Date : Dec 31, 2019
Study Type : Human Study
Additional Links
Diseases : Brain Concussion, Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Neuroprotective Agents
[+]

Increased circulating stem cells and better cognitive performance was seen in traumatic brain injury subjects following hyperbaric oxygen therapy.Apr 30, 2017

Pubmed Data : Undersea Hyperb Med. 2017 May-Jun;44(3):257-269. PMID: 28779582
Article Published Date : Apr 30, 2017
Study Type : Human Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Neuroprotective Agents
[+]

Transcranial LED treatment improved sleep and led to fewer post-traumatic stress disorder symptoms.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurotrauma. 2014 Jun 1 ;31(11):1008-17. Epub 2014 May 8. PMID: 24568233
Article Published Date : May 31, 2014
Study Type : Human Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Light-Emitting Diodes (LEDs) Therapy
[+]

Traumatic brain injury patients on clopidogrel may have increased long-term disability and fatal consequences when compared with patients who are not on these drugs or on other anticoagulants. Dec 01, 2008

Pubmed Data : J Trauma. 2008 Dec;65(6):1303-8. PMID: 19077618
Article Published Date : Dec 01, 2008
Study Type : Human Study
Additional Links
Diseases : Traumatic Brain Injury
Problem Substances : Clopidogrel
[+]

Yoga-based physical therapy is feasible and safe in the inpatient rehabilitation setting following traumatic brain injury.Jun 11, 2020

Pubmed Data : Brain Inj. 2020 Jun 12:1-9. Epub 2020 Jun 12. PMID: 32530717
Article Published Date : Jun 11, 2020
Study Type : Human Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Yoga
[+]

A case report of restoration of function with acupuncture following severe traumatic brain injury.Oct 31, 2015

Pubmed Data : Glob Adv Health Med. 2015 Nov ;4(6):52-7. Epub 2015 Nov 1. PMID: 26665023
Article Published Date : Oct 31, 2015
Study Type : Human: Case Report
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Acupuncture
[+]

A patient reported rapid and significant improvements in pain and mood during a course of acupuncture treatment. Aug 31, 2006

Pubmed Data : Acupunct Med. 2006 Sep ;24(3):129-33. PMID: 17013360
Article Published Date : Aug 31, 2006
Study Type : Human: Case Report
Additional Links
Diseases : Central Pain Syndrome, Fractures: Bone, Traumatic Brain Injury
Therapeutic Actions : Acupuncture
Pharmacological Actions : Analgesics
Additional Keywords : Significant Treatment Outcome
[+]

Administration of synthetic 2-AG to mice after CHI led to significant reduction of brain oedema, better clinical recovery, reduced infarct volume and reduced hippocampal cell death compared with controls.Oct 03, 2001

Pubmed Data : Nature. 2001 Oct 4 ;413(6855):527-31. PMID: 11586361
Article Published Date : Oct 03, 2001
Study Type : Animal Study
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Brain Edema, Brain Inflammation , Traumatic Brain Injury
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Significant Treatment Outcome
[+]

Allyl isothiocyanate attenuates oxidative stress and inflammation by modulating Nrf2/HO-1 and NF-κB pathways in traumatic brain injury.Jan 31, 2019

Pubmed Data : Mol Biol Rep. 2019 Feb ;46(1):241-250. Epub 2018 Nov 8. PMID: 30406889
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Isothiocyanates
Diseases : Brain: Oxidative Stress, Inflammation, Traumatic Brain Injury
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation
[+]

Auricular electroacupuncture can reduce the incidence of late post-traumatic epilepsy.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2019 ;2019:5798912. Epub 2019 Oct 13. PMID: 31737082
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Epilepsy, Traumatic Brain Injury
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Neuroprotective Agents
[+]

Chrysin could be beneficial for protection against traumatic brain injury-associated behavioural deficits.Feb 21, 2020

Pubmed Data : Psychopharmacology (Berl). 2020 Feb 22. Epub 2020 Feb 22. PMID: 32088834
Article Published Date : Feb 21, 2020
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Memory Disorders, Traumatic Brain Injury
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Neuroprotective Agents
[+]

Dietary choline supplementation improves behavioral, histological, and neurochemical outcomes in a rat model of traumatic brain injury.Aug 01, 2008

Pubmed Data : J Neurotrauma. 2008 Aug;25(8):975-83. PMID: 18665805
Article Published Date : Aug 01, 2008
Study Type : Animal Study
Additional Links
Substances : Choline
Diseases : Brain Inflammation , Traumatic Brain Injury
[+]

Diosmin improved cognitive deficit and amplified brain electrical activity in the rat model of traumatic brain injury.Aug 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Sep ;93:1220-1229. Epub 2017 Jul 20. PMID: 28738538
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Diosmin
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ellagic acid can restore neurologic severity score, cognitive and long-term potentiation deficits and prevent brain inflammation.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Basic Med Sci. 2017 Apr ;20(4):399-407. PMID: 28804609
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Traumatic Brain Injury
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ellagic acid may be used in functional foods or medicines to help treat nerve dysfunction, neurodegenerative disease and aging.Oct 28, 2016

Pubmed Data : Mol Nutr Food Res. 2016 Oct 29. Epub 2016 Aug 29. PMID: 27794200
Article Published Date : Oct 28, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ellagic Acid
Diseases : Neurodegenerative Diseases, Traumatic Brain Injury
Pharmacological Actions : Wnt/β-catenin signaling pathway modulation
[+]

Ellagic acid prevents cognitive and hippocampal long-term potentiation deficits and brain inflammation in rat with traumatic brain injury.Feb 28, 2015

Pubmed Data : Life Sci. 2015 Mar 1 ;124:120-7. Epub 2015 Jan 28. PMID: 25637685
Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Substances : Ellagic Acid
Diseases : Brain Inflammation , Memory Disorders, Traumatic Brain Injury
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

Hydrogen rich water can up-regulate the expression of Nrf2, and reduce oxidative damage of traumatic brain injury.Oct 31, 2015

Pubmed Data : Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2015 Nov ;27(11):911-5. PMID: 27132459
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Oxidative Stress, Traumatic Brain Injury
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Hyperbaric oxygen has a neuroprotective role in traumatic brain injury.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genet Mol Res. 2016 ;15(1). Epub 2016 Jan 29. PMID: 26909929
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Apoptotic, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
[+]

Hyperbaric oxygen promotes neural stem cell proliferation after traumatic brain injury.Sep 24, 2017

Pubmed Data : Neuroreport. 2017 Sep 25. Epub 2017 Sep 25. PMID: 28953090
Article Published Date : Sep 24, 2017
Study Type : Animal Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Neuroprotective Agents
[+]

Hyperbaric oxygen therapy treatment improves the cumulative tissue damage in juvenile brain following repetitive mild traumatic brain injury.Sep 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Gas Res. 2016 Oct-Dec;6(4):187-193. Epub 2016 Dec 30. PMID: 28217290
Article Published Date : Sep 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Neuroprotective Agents
[+]

Hyperbaric oxygen therapy treatment may ameliorate TBI-induced depression-like behaviour in rats by attenuating neuro-inflammation.Jan 04, 2017

Pubmed Data : World Neurosurg. 2017 Jan 5. Epub 2017 Jan 5. PMID: 28065873
Article Published Date : Jan 04, 2017
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage.Jun 12, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2017 Jun 13 ;14(1):119. Epub 2017 Jun 13. PMID: 28610608
Article Published Date : Jun 12, 2017
Study Type : Animal Study
Additional Links
Substances : Isoliquiritigenin
Diseases : Intracerebral Hemorrhage, Traumatic Brain Injury
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents, Nrf2 activation
[+]

Lactobacillus acidophilus exerts neuroprotective effects in mice with traumatic brain injury.Jun 06, 2019

Pubmed Data : J Nutr. 2019 Jun 7. Epub 2019 Jun 7. PMID: 31174208
Article Published Date : Jun 06, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus Acidophilus
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Magnesium administration after experimental traumatic brain injury improves decision-making skills.Apr 30, 2018

Pubmed Data : Brain Res Bull. 2018 May ;139:182-189. Epub 2018 Mar 1. PMID: 29501800
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : magnesium chloride
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Melatonin attenuates sepsis induced brain injury via activation SIRT1 signaling activation.Jun 09, 2015

Pubmed Data : J Pineal Res. 2015 Jun 10. Epub 2015 Jun 10. PMID: 26094939
Article Published Date : Jun 09, 2015
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Brain: Oxidative Stress, Brain Inflammation , Sepsis, Traumatic Brain Injury
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, SIRT1 Activator, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Significant Treatment Outcome
[+]

Neuronal degenerative findings and the secondary brain damage and ischemia caused by oxidative stress are decreased by CoQ10 use in rats with traumatic brain injury.Jan 01, 2011

Pubmed Data : BMC Neurosci. 2011 ;12:75. Epub 2011 Jul 29. PMID: 21801363
Article Published Date : Jan 01, 2011
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Brain Damage, Brain Ischemia, Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Neuroprotective effect of artesunate in experimental model of traumatic brain injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurol. 2018 ;9:590. Epub 2018 Jul 31. PMID: 30108544
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Artesunate
Diseases : Traumatic Brain Injury
Pharmacological Actions : Anti-Inflammatory Agents, Brain-derived neurotrophic factor modulator, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Neuroprotective effect of berberine against learning and memory deficits in diffuse axonal injuryDec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2018 Jan ;15(1):1129-1135. Epub 2017 Nov 13. PMID: 29399112
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Learning disorders, Traumatic Brain Injury
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Neuroprotective effect of berberine agonist against impairment of learning and memory skills in severe traumatic brain injury.Mar 04, 2018

Pubmed Data : Mol Med Rep. 2018 Mar 5. Epub 2018 Mar 5. PMID: 29512719
Article Published Date : Mar 04, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Traumatic Brain Injury
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Matrix metalloproteinase-3 (MMP-3) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Neuroprotective Agents
[+]

Oleocanthal has a protective effect on neural cells after traumatic brain injury.Oct 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Turk Neurosurg. 2017 Nov 1. Epub 2017 Nov 1. PMID: 29204981
Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Oleocanthal, Olive Oil
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Palmitoylethanolamide reduces neuropsychiatric behaviours by restoring cortical electrophysiological activity in a model of mild traumatic brain injury.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:95. Epub 2017 Mar 6. PMID: 28321191
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Pre and post treatment with ascorbic acid and α-tocopherol reduced oxidative stress induced by brain injury and effectively reduced mortality rate in rats.Jun 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neurosci Rural Pract. 2013 Jul ;4(3):292-7. PMID: 24250162
Article Published Date : Jun 30, 2013
Study Type : Animal Study
Additional Links
Substances : Vitamin C, Vitamin E: alpha tocopherol
Diseases : Brain: Oxidative Stress, Traumatic Brain Injury
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Additional Keywords : Significant Treatment Outcome
[+]

Propolis may protect brain cell from apoptosis after injury by maintaining Hsp70 expression in addition to antioxidant and anti-inflammatory.Sep 14, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Open Access Maced J Med Sci. 2019 Sep 15 ;7(17):2763-2766. Epub 2019 Aug 30. PMID: 31844433
Article Published Date : Sep 14, 2019
Study Type : Animal Study
Additional Links
Substances : Propolis: Bee
Diseases : Traumatic Brain Injury
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Heat Shock Protein Inducer, Neuroprotective Agents
[+]

Quercetin protects rat cortical neurons against traumatic brain injury.Mar 27, 2018

Pubmed Data : Mol Med Rep. 2018 Mar 28. Epub 2018 Mar 28. PMID: 29620218
Article Published Date : Mar 27, 2018
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Resveratrol attenuates behavioral impairments and reduces cortical and hippocampal loss in a rat controlled cortical impact model of traumatic brain injury.Jun 01, 2010

Pubmed Data : J Neurotrauma. 2010 Jun;27(6):1091-9. PMID: 20560755
Article Published Date : Jun 01, 2010
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Brain Injury: Hippocampal Damage, Traumatic Brain Injury
Pharmacological Actions : Apoptotic, Neuroprotective Agents
Additional Keywords : Stilbenes
[+]

Sesamin may be a promising potential therapeutic intervention for preventing disruption of the blood brain barrier after traumatic brain injury.Aug 02, 2017

Pubmed Data : Acta Pharmacol Sin. 2017 Aug 3. Epub 2017 Aug 3. PMID: 28770828
Article Published Date : Aug 02, 2017
Study Type : Animal Study
Additional Links
Substances : Sesamin
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Sesamin protected SH-SY5Y cells against stretch injury by attenuating increases in ROS levels and suppressing apoptosis.Aug 06, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Neurosci. 2017 Aug 7 ;18(1):57. Epub 2017 Aug 7. PMID: 28784087
Article Published Date : Aug 06, 2017
Study Type : Animal Study
Additional Links
Substances : Sesamin
Diseases : Traumatic Brain Injury
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Silymarin can significantly reduce anxiety and depression-like symptoms, and neuroinflammation after mild traumatic brain injury.Dec 31, 2017

Pubmed Data : Toxicol Appl Pharmacol. 2018 Jan 1 ;338:159-173. Epub 2017 Nov 22. PMID: 29175455
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Silymarin
Diseases : Depression, Traumatic Brain Injury
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substances Versus Drugs
Problem Substances : Fluoxetine (trade name Prozac)
[+]

Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injury.Nov 15, 2005

Pubmed Data : J Neurosci Res. 2005 Nov 15;82(4):499-506. PMID: 16211562
Article Published Date : Nov 15, 2005
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Brain Edema, Traumatic Brain Injury
[+]

Sulforphane attenuates oxidative stress and neuronal damage following traumatic brain injury. Oct 18, 2010

Pubmed Data : Acta Pharmacol Sin. 2010 Oct 18. Epub 2010 Oct 18. PMID: 20953205
Article Published Date : Oct 18, 2010
Study Type : Animal Study
Additional Links
Substances : Sulforaphane
Diseases : Brain Injury: Traumatic, Traumatic Brain Injury
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Tauroursodeoxycholic acid may attenuate early brain injury via Akt pathway activation.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Cell Neurosci. 2017 ;11:193. Epub 2017 Jul 6. PMID: 28729823
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Tauroursodeoxycholic acid
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Tetrahydrocurcumin provides neuroprotection in experimental traumatic brain injury.Dec 31, 2016

Pubmed Data : Neuroimmunomodulation. 2017 ;24(6):348-355. Epub 2018 Apr 18. PMID: 29669346
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Tetrahydrocurcumin
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents, Nrf2 activation
[+]

The benefits of voluntary physical exercise after traumatic brain injury on rat's object recognition memory.Jan 07, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Neurol. 2020 Jan 8:113178. Epub 2020 Jan 8. PMID: 31926165
Article Published Date : Jan 07, 2020
Study Type : Animal Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Exercise
Pharmacological Actions : Neurogenesis, Neuroprotective Agents
[+]

The results of this study demonstrated that genistein can be neuroprotective in traumatic brain injury. Sep 10, 2015

Pubmed Data : Physiol Behav. 2015 Sep 11 ;152(Pt A):26-31. Epub 2015 Sep 11. PMID: 26367454
Article Published Date : Sep 10, 2015
Study Type : Animal Study
Additional Links
Substances : Genistein
Diseases : Brain Edema, Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Therapeutic effects of chrysin in a model of traumatic brain injuryJun 30, 2019

Pubmed Data : Life Sci. 2019 Jul 1 ;228:285-294. Epub 2019 May 4. PMID: 31063733
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Chrysin
Diseases : Brain: Oxidative Stress, Learning disorders, Memory Disorders, Traumatic Brain Injury
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
[+]

These findings demonstrated that low-molecular-weight fucoidan exerts neuroprotection against traumatic brain injury in the aged brain.Oct 31, 2016

Pubmed Data : Cell Mol Neurobiol. 2016 Nov ;36(8):1257-1268. Epub 2016 Jan 7. PMID: 26743530
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Fucoidan
Diseases : Oxidative Stress, Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

These results suggest that crocin has neuroprotective effects against traumatic brain injury in mice.Mar 29, 2015

Pubmed Data : Neurosci Lett. 2015 Mar 30 ;591:53-8. Epub 2015 Feb 11. PMID: 25681620
Article Published Date : Mar 29, 2015
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

This study indicates that tetrahydrocurcumin protects neurons from traumatic brain injury-induced apoptotic neuronal death.Oct 31, 2016

Pubmed Data : J Surg Res. 2016 Nov ;206(1):67-76. Epub 2016 Jul 15. PMID: 27916377
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Tetrahydrocurcumin
Diseases : Traumatic Brain Injury
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

Thymoquinone has a healing effect on neural cells after head injury and this effect is mediated by decreasing MDA levels.Sep 29, 2015

Pubmed Data : World Neurosurg. 2015 Sep 30. Epub 2015 Sep 30. PMID: 26428323
Article Published Date : Sep 29, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Thymoquinone
Diseases : Traumatic Brain Injury
Pharmacological Actions : Malondialdehyde Down-regulation, Neuroprotective Agents
[+]

Ubiquinol preserves mitochondria and reduces cellular injury severity after traumatic brain injury.Jan 29, 2018

Pubmed Data : J Neurosci Res. 2018 Jan 30. Epub 2018 Jan 30. PMID: 29380912
Article Published Date : Jan 29, 2018
Study Type : Animal Study
Additional Links
Substances : Ubiquinol
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Withaferin A alleviates traumatic brain injury induced secondary brain injury via suppressing apoptosis in endothelia cells and modulating activation in the microglia.May 04, 2020

Pubmed Data : Eur J Pharmacol. 2020 May 5 ;874:172988. Epub 2020 Feb 4. PMID: 32032599
Article Published Date : May 04, 2020
Study Type : In Vitro Study
Additional Links
Substances : Ashwagandha
Diseases : Traumatic Brain Injury
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
[+]

A review of the promising therapeutic potential of pterostilbene.Jul 26, 2016

Pubmed Data : Eur J Pharmacol. 2016 Jul 27 ;789:229-243. Epub 2016 Jul 27. PMID: 27475678
Article Published Date : Jul 26, 2016
Study Type : Review
Additional Links
Substances : Pterostilbene
Diseases : Cancers: All, Cardiovascular Diseases, Traumatic Brain Injury
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
[+]

Curcumin could increase the levels of BDNF, GAP-43, ICAM, and Nrf2 and attenuate brain injury in the model of traumatic brain injury.May 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Curr Dev Nutr. 2019 Jun ;3(Suppl 1). Epub 2019 Jun 13. PMID: 31225014
Article Published Date : May 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Curcuma Longa
Diseases : Traumatic Brain Injury
Pharmacological Actions : Antioxidants, Brain-derived neurotrophic factor modulator, Neuroprotective Agents, Nrf2 activation
[+]

Glycyrrhizin improved the neurological function recovery, reduced the lesion volume, and inhibited the release and expression of HMGB1 after TBI.Jan 25, 2018

Pubmed Data : Biochem Biophys Res Commun. 2018 02 26 ;497(1):430-436. Epub 2018 Feb 12. PMID: 29448108
Article Published Date : Jan 25, 2018
Study Type : In Vitro Study
Additional Links
Substances : Glycyrrhizin
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

High-dose intravenous vitamin C may prove an effective strategy to prevent or mitigate secondary brain injury.Dec 31, 2019

Pubmed Data : Neurocrit Care. 2020 02 ;32(1):333-339. PMID: 31440996
Article Published Date : Dec 31, 2019
Study Type : Commentary
Additional Links
Substances : Vitamin C: Intravenous
Diseases : Brain: Oxidative Stress, Traumatic Brain Injury
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Hyperbaric oxygen therapy alleviates the inflammatory response in experimental traumatic brain injury.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 Oct ;16(4):3922-3928. Epub 2017 Jul 24. PMID: 29067455
Article Published Date : Sep 30, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : anti-inflammatory, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Hyperbaric oxygen therapy has been demonstrated to have neuroprotective effects without increased oxygen toxicity in experimental TBI models.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Gas Res. 2016 Apr-Jun;6(2):102-110. Epub 2016 Jul 11. PMID: 27867476
Article Published Date : Mar 31, 2016
Study Type : Review
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Neuroprotective Agents
[+]

Hyperbaric oxygen therapy has the potential to be the first significant treatment in the acute phase of severe traumatic brain injury.Nov 12, 2017

Pubmed Data : J Neurotrauma. 2017 Nov 13. Epub 2017 Nov 13. PMID: 29132229
Article Published Date : Nov 12, 2017
Study Type : Review
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Neuroprotective Agents
[+]

Low level laser treatment may have a role in neurorehabilitation. Dec 01, 2010

Pubmed Data : PM R. 2010 Dec ;2(12 Suppl 2):S292-305. PMID: 21172691
Article Published Date : Dec 01, 2010
Study Type : Review
Additional Links
Diseases : Brain Damage, Head Injuries, Traumatic Brain Injury
Therapeutic Actions : Laser Treatment: Low-Level
[+]

N. sativa and thymoquinone have protective effects against neurodegenerative diseases.Dec 31, 2017

Pubmed Data : CNS Neurol Disord Drug Targets. 2018 07 1. Epub 2018 Jul 1. PMID: 29962349
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Nigella sativa (aka Black Seed), Thymoquinone
Diseases : Alzheimer's Disease, Depression, Epilepsy, Ischemia, Neurodegenerative Diseases, Parkinson's Disease, Traumatic Brain Injury
Pharmacological Actions : Antidepressive Agents, Neuroprotective Agents
[+]

Neuroprotective effects of curcumin through autophagy modulation.Dec 04, 2019

Pubmed Data : IUBMB Life. 2019 Dec 5. Epub 2019 Dec 5. PMID: 31804772
Article Published Date : Dec 04, 2019
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Alexander Disease, Alzheimer's Disease, Parkinson's Disease, Stroke: Ischemic, Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Piperine attenuates TBI-induced seizures via inhibiting cytokine-activated reactive astrogliosis.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurol. 2020 ;11:431. Epub 2020 Jun 4. PMID: 32655468
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Piperine
Diseases : Seizures, Traumatic Brain Injury
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Resveratrol treatment attenuates the nigrostriatal pathway injury-induced neuronal apoptosis and inflammation.Oct 17, 2016

Pubmed Data : Brain Res. 2016 Oct 18. Epub 2016 Aug 18. PMID: 27769789
Article Published Date : Oct 17, 2016
Study Type : In Vitro Study
Additional Links
Substances : Resveratrol
Diseases : Traumatic Brain Injury
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The evidence presented in this paper appears to be supporting the hypothesis that Nigella sativa can enhance learning and memory.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:6075679. Epub 2016 Feb 28. PMID: 27022403
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Nigella sativa (aka Black Seed), Thymoquinone
Diseases : Memory Disorders, Neurodegenerative Diseases, Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

This review discusses the neuroprotective potential of resveratrol in stroke, traumatic brain injury and spinal cord injury.Aug 11, 2015

Pubmed Data : Neurochem Int. 2015 Aug 12. Epub 2015 Aug 12. PMID: 26277384
Article Published Date : Aug 11, 2015
Study Type : Review
Additional Links
Substances : Resveratrol
Diseases : Spinal Cord Injuries, Stroke: Attenuation/Recovery , Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
[+]

Transcranial light-emitting diode therapy could be used for neuropsychological improvement after traumatic brain injury.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Devices (Auckl). 2018 ;11:139-146. Epub 2018 Apr 26. PMID: 29731669
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Diseases : Traumatic Brain Injury
Therapeutic Actions : Light-Emitting Diode Therapy
Pharmacological Actions : Neuroprotective Agents

Copyright: alila / 123RF Stock Photo

Traumatic Brain Injury Related Articles

VACCINE INJURY: First the Gut, Then the Brain
Written by Keith Bell
When we think about vaccine injuries such as autism and epilepsy, we generally consider a direct assault on the brain. But the reality may be far different where injury begins in the gut, leading to brain damage.

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Connect with GreenMedInfo

MeWe

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.