Traumatic Brain Injury

Name	AC	CK
Frankincense	2	20
Flavonoids	3	15
Ginkgo biloba	2	12
Vinpocetine	2	12
Acetyl-l-carnitine	1	10
Alpha-Lipoic Acid	1	10
Fish Oil	1	10
Folic Acid	1	10
Ginger	1	10
Huperzine	1	10
Multivitamin	1	10
NAC (N-acetyl-L-cysteine)	1	10
Resveratrol	5	8
Thymoquinone	5	7
Ellagic Acid	3	6
Chrysin	3	5
Melatonin	3	5
Astaxanthin	2	4
Berberine	2	4
Hydrogen: Molecular	2	4
Nigella sativa (aka Black Seed)	3	4
Safflower	2	4
Sesamin	2	4
Sulforaphane	2	4
Tetrahydrocurcumin	2	4
Curcumin	2	3
Aloe Vera	1	2
Artesunate	1	2
Caffeic acid phenethyl ester	1	2
Cannabidiol	1	2
Cannabinoids	1	2
Carvacrol	1	2
Choline	1	2
Cinnamaldehyde	1	2
Coenzyme Q10	1	2
Crocetin	1	2
Crocin	1	2
Diosmin	1	2
Endocannabinoids	1	2
Formononetin	2	2
Fucoidan	1	2
Gastrodin	1	2
Genistein	1	2
Honokiol	1	2
Hydrogen Water	1	2
Icariin	1	2
Isoliquiritigenin	1	2
Isothiocyanates	1	2
Lactobacillus Acidophilus	1	2
Lactobacillus reuteri	1	2
Lupeol	1	2
Naringenin	1	2
Oleocanthal	1	2
Olive Oil	1	2
Palmitoylethanolamide	1	2
Propolis: Bee	1	2
Quercetin	1	2
Saffron	1	2
Shilajit	1	2
Silymarin	1	2
Tangeretin	1	2
Tauroursodeoxycholic acid	1	2
Ubiquinol	1	2
Urolithin A	1	2
Ursolic Acid	1	2
Vitamin C	1	2
Vitamin E: alpha tocopherol	1	2
Wogonin	1	2
magnesium chloride	1	2
Ashwagandha	1	1
Asiatic Acid	1	1
Curcuma Longa	1	1
Ginsenosides	1	1
Glycyrrhizin	1	1
Omega-3 Fatty Acids	1	1
Phloretin	1	1
Piperine	1	1
Pterostilbene	1	1
Vitamin C: Intravenous	1	1

Name	AC	CK	Focus
Clopidogrel	1	10
Fluoxetine (trade name Prozac)	1	2

Name	AC	CK
Hyperbaric Treatment	12	61
Yoga	3	40
Acupuncture	5	38
Qigong	1	21
Tai Chi	1	21
Meditation	1	20
Mindfullness Training	1	20
Electroacupuncture	5	17
Dietary Modification: Low Carbohydrate/Ketogenic	3	13
Acupressure	1	10
Light-Emitting Diodes (LEDs) Therapy	1	10
Exercise	1	2
Ultrasound therapy	1	2
Laser Treatment: Low-Level	1	1
Light-Emitting Diode Therapy	1	1

[+]

Effects of tai chi and Qigong on cognition in neurological disorders.Jun 11, 2022

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Pubmed Data : Geriatr Nurs. 2022 Jun 12 ;46:166-177. Epub 2022 Jun 12. PMID: 35704955

Article Published Date : Jun 11, 2022

Study Type : Meta Analysis, Review

Additional Links

Diseases : Dementia, Neurological Conditions, Stroke, Traumatic Brain Injury

Therapeutic Actions : Qigong, Tai Chi

Pharmacological Actions : Neuroprotective Agents

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Acupuncture can be an effective treatment for patients unconscious following traumatic brain injury.Feb 20, 2020

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Pubmed Data : Altern Ther Health Med. 2020 Feb 21. Epub 2020 Feb 21. PMID: 32088667

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Pubmed Data : J Psychoactive Drugs. 2011 Jan-Mar;43(1):1-5. PMID: 21615001

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Pubmed Data : Chin J Integr Med. 2022 May 4. Epub 2022 May 4. PMID: 35508860

Article Published Date : May 03, 2022

Study Type : Human Study

Additional Links

Diseases : Traumatic Brain Injury

Therapeutic Actions : Electroacupuncture

Pharmacological Actions : Gastroprotective

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Effect of a Boswellia and ginger mixture on the memory dysfunction of the mild traumatic brain injury patients.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Bull Emerg Trauma. 2022 ;10(4):157-164. PMID: 36568722

Article Published Date : Dec 31, 2021

Study Type : Human Study

Additional Links

Substances : Frankincense, Ginger

Diseases : Traumatic Brain Injury

Pharmacological Actions : Neuroprotective Agents

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Effects of intravascular photobiomodulation on cognitive impairment and crossed cerebellar diaschisis in patients with traumatic brain injury.Apr 19, 2023

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Pubmed Data : Lasers Med Sci. 2023 Apr 20 ;38(1):108. Epub 2023 Apr 20. PMID: 37076743

Article Published Date : Apr 19, 2023

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Pubmed Data : Clin Nutr ESPEN. 2022 Feb ;47:339-345. Epub 2021 Nov 16. PMID: 35063224

Article Published Date : Jan 31, 2022

Study Type : Human Study

Additional Links

Diseases : Traumatic Brain Injury

Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic

Pharmacological Actions : Neuroprotective Agents

[+]

Transcranial LED treatment improved sleep and led to fewer post-traumatic stress disorder symptoms.May 31, 2014

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Acupunct Med. 2006 Sep ;24(3):129-33. PMID: 17013360

Article Published Date : Aug 31, 2006

Study Type : Human: Case Report

Additional Links

Diseases : Central Pain Syndrome, Fractures: Bone, Traumatic Brain Injury

Therapeutic Actions : Acupuncture

Pharmacological Actions : Analgesics

Additional Keywords : Significant Treatment Outcome

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Agathisflavone modulates astrocytic responses and increases the population of neurons in an in vitro model of traumatic brain injury.Jan 09, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Mol Biol Rep. 2019 Feb ;46(1):241-250. Epub 2018 Nov 8. PMID: 30406889

Article Published Date : Jan 31, 2019

Study Type : Animal Study

Additional Links

Substances : Isothiocyanates

Diseases : Brain: Oxidative Stress, Inflammation, Traumatic Brain Injury

Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Nrf2 activation

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Aloe vera leaf extract reduced BBB permeability and improved neurological results after traumatic brain injury.Dec 31, 2023

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Pubmed Data : Oxid Med Cell Longev. 2024 ;2024:5586814. Epub 2024 Jul 15. PMID: 39040520

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Pubmed Data : Brain Inj. 2024 Mar 3:1-7. Epub 2024 Mar 3. PMID: 38433503

Article Published Date : Mar 02, 2024

Study Type : Animal Study

Additional Links

Substances : Crocetin

Diseases : Traumatic Brain Injury

Pharmacological Actions : Neuroprotective Agents

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Curcumin has neuroprotective effects in traumatic brain injury models.Mar 02, 2023

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Pubmed Data : Curr Neurovasc Res. 2023 Mar 3. Epub 2023 Mar 3. PMID: 36872351

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Ginkgolide A attenuated apoptosis via inhibition of oxidative stress in mice with traumatic brain injury.Jan 29, 2024

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Pubmed Data : Neuroreport. 2017 Sep 25. Epub 2017 Sep 25. PMID: 28953090

Article Published Date : Sep 24, 2017

Study Type : Animal Study

Additional Links

Diseases : Traumatic Brain Injury

Therapeutic Actions : Hyperbaric Treatment

Pharmacological Actions : Neuroprotective Agents

[+]

Hyperbaric oxygen therapy treatment improves the cumulative tissue damage in juvenile brain following repetitive mild traumatic brain injury.Sep 30, 2016

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Pubmed Data : Med Gas Res. 2016 Oct-Dec;6(4):187-193. Epub 2016 Dec 30. PMID: 28217290

Article Published Date : Sep 30, 2016

Study Type : Animal Study

Additional Links

Diseases : Traumatic Brain Injury

Therapeutic Actions : Hyperbaric Treatment

Pharmacological Actions : Neuroprotective Agents

[+]

Hyperbaric oxygen therapy treatment may ameliorate TBI-induced depression-like behaviour in rats by attenuating neuro-inflammation.Jan 04, 2017

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Pubmed Data : World Neurosurg. 2017 Jan 5. Epub 2017 Jan 5. PMID: 28065873

Article Published Date : Jan 04, 2017

Study Type : Animal Study

Additional Links

Diseases : Brain Inflammation , Traumatic Brain Injury

Therapeutic Actions : Hyperbaric Treatment

Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Inhibition of NOX2 contributes to the therapeutic effect of aloin on traumatic brain injury.Dec 31, 2019

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Pubmed Data : Exp Ther Med. 2018 Jan ;15(1):1129-1135. Epub 2017 Nov 13. PMID: 29399112

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Learning disorders, Traumatic Brain Injury

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Neuroprotective effect of berberine agonist against impairment of learning and memory skills in severe traumatic brain injury.Mar 04, 2018

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Pubmed Data : Mol Med Rep. 2018 Mar 5. Epub 2018 Mar 5. PMID: 29512719

Article Published Date : Mar 04, 2018

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Traumatic Brain Injury

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Matrix metalloproteinase-3 (MMP-3) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Neuroprotective Agents

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Neurosci Rural Pract. 2013 Jul ;4(3):292-7. PMID: 24250162

Article Published Date : Jun 30, 2013

Study Type : Animal Study

Additional Links

Substances : Vitamin C, Vitamin E: alpha tocopherol

Diseases : Brain: Oxidative Stress, Traumatic Brain Injury

Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents

Additional Keywords : Significant Treatment Outcome

[+]

Propolis may protect brain cell from apoptosis after injury by maintaining Hsp70 expression in addition to antioxidant and anti-inflammatory.Sep 14, 2019

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Pubmed Data : Mol Med Rep. 2018 Mar 28. Epub 2018 Mar 28. PMID: 29620218

Article Published Date : Mar 27, 2018

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Traumatic Brain Injury

Pharmacological Actions : Neuroprotective Agents

[+]

Resveratrol attenuates autophagy and inflammation after traumatic brain injury.Dec 31, 2021

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Pubmed Data : Folia Neuropathol. 2022 ;60(2):153-164. PMID: 35950468

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Brain Inflammation , Traumatic Brain Injury

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injury.Nov 15, 2005

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Pubmed Data : J Neurosci Res. 2005 Nov 15;82(4):499-506. PMID: 16211562

Article Published Date : Nov 15, 2005

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Brain Edema, Traumatic Brain Injury

[+]

Sulforphane attenuates oxidative stress and neuronal damage following traumatic brain injury. Oct 18, 2010

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Pubmed Data : Acta Pharmacol Sin. 2010 Oct 18. Epub 2010 Oct 18. PMID: 20953205

Article Published Date : Oct 18, 2010

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Brain Injury: Traumatic, Traumatic Brain Injury

Pharmacological Actions : Antioxidants, Neuroprotective Agents

[+]

Tanshinone IIA alleviates traumatic brain Injury by reducing ischemia‒reperfusion.Dec 31, 2023

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Pubmed Data : Mediators Inflamm. 2024 ;2024:7459054. Epub 2024 Mar 21. PMID: 38549714

Article Published Date : Dec 31, 2023

Study Type : Animal Study

Additional Links

Substances : Tanshinone IIA

Diseases : Traumatic Brain Injury

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : MicroRNA-124

[+]

Tauroursodeoxycholic acid may attenuate early brain injury via Akt pathway activation.Dec 31, 2016

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Focusing on formononetin: recent perspectives for its neuroprotective potentials.Dec 31, 2021

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Pubmed Data : Front Pharmacol. 2022 ;13:905898. Epub 2022 May 30. PMID: 35712702

Article Published Date : Dec 31, 2021

Study Type : Review

Additional Links

Substances : Formononetin

Diseases : Alzheimer's Disease, Anxiety, Brain Inflammation , Dementia, Depression, Ischemia, Traumatic Brain Injury

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents

[+]

Formononetin: A pathway to protect neurons. Dec 31, 2021

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Pubmed Data : IUBMB Life. 2019 Dec 5. Epub 2019 Dec 5. PMID: 31804772

Article Published Date : Dec 04, 2019

Study Type : Review

Additional Links

Substances : Curcumin

Diseases : Alexander Disease, Alzheimer's Disease, Parkinson's Disease, Stroke: Ischemic, Traumatic Brain Injury

Pharmacological Actions : Neuroprotective Agents

[+]

Neuroprotective mechanisms of asiatic acid.Apr 30, 2023

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Pubmed Data : PLoS One. 2022 ;17(3):e0264533. Epub 2022 Mar 3. PMID: 35239693

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Diseases : Traumatic Brain Injury

Therapeutic Actions : Photobiomodulation

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

Piperine attenuates TBI-induced seizures via inhibiting cytokine-activated reactive astrogliosis.Dec 31, 2019

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Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:6075679. Epub 2016 Feb 28. PMID: 27022403

Article Published Date : Dec 31, 2015

Study Type : Review

Additional Links

Substances : Nigella sativa (aka Black Seed), Thymoquinone

Diseases : Memory Disorders, Neurodegenerative Diseases, Traumatic Brain Injury

Pharmacological Actions : Neuroprotective Agents

[+]

The results strongly suggest that acupuncture has multiple benefits against traumatic brain injury.Dec 31, 2021

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View the Evidence: 147 Abstracts with Traumatic Brain Injury Research

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Effects of tai chi and Qigong on cognition in neurological disorders.Jun 11, 2022

Acupuncture can be an effective treatment for patients unconscious following traumatic brain injury.Feb 20, 2020

Patients undergoing hyperbaric therapy achieved significant improvement in the GCS and GOS with a lower overall mortality.Apr 30, 2016

Therapeutic effects of meditation, yoga, and mindfulness-based interventions for chronic symptoms of mild traumatic brain injury.Nov 01, 2020

A nutrient combination improves cognitive function in head injuried former NFL players. Jan 01, 2011

Acupuncture treatment increased the cortico spinal tract activity of patients with chronic chronic disorders of consciousness after severe TBI.Oct 31, 2016

Boswellia serrata extract shows cognitive benefits.Apr 05, 2022

Early electroacupuncture can improve gastrointestinal function and clinical prognosis in patients with traumatic brain injury complicated by gastrointestinal injury.May 03, 2022

Effect of a Boswellia and ginger mixture on the memory dysfunction of the mild traumatic brain injury patients.Dec 31, 2021

Effects of intravascular photobiomodulation on cognitive impairment and crossed cerebellar diaschisis in patients with traumatic brain injury.Apr 19, 2023

Effects of self-administered acupressure on fatigue following traumatic brain injury.Mar 22, 2023

Feasibility of yoga to improve symptoms in individuals with severe, chronic traumatic brain injury.Jan 07, 2021

Folic acid treatment in TBI patients has the potential for preventing and treating hospital acquired pneumonia.Dec 13, 2022

From dawn to dusk-mimicking natural daylight exposure improves circadian rhythm entrainment in patients with severe brain injury.Jul 10, 2022

HBOT was significantly effective for veterans with mild to moderate traumatic brain injury with persistent post-concussion syndrome and PTSD.Jun 30, 2017

Hyperbaric oxygen therapy can improve pain symptoms, quality of life, emotional and social function of patients suffering from fibromyalgia triggered by TBI.Dec 31, 2022

Hyperbaric oxygen therapy can induce angiogenesis and regeneration of nerve fibers in traumatic brain injury patients.Dec 31, 2016

Hyperbaric oxygen therapy for mild traumatic brain injury persistent postconcussion syndrome.Dec 31, 2019

Increased circulating stem cells and better cognitive performance was seen in traumatic brain injury subjects following hyperbaric oxygen therapy.Apr 30, 2017

Oligopin supplementation in traumatic brain injury patients in ICU reduced inflammation and improved the clinical status.Aug 31, 2021

This pilot study shows that ketogenic diet is feasible in the management of traumatic brain injury patients.Jan 31, 2022

Transcranial LED treatment improved sleep and led to fewer post-traumatic stress disorder symptoms.May 31, 2014