Venous Ulcer

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7 Substances Researched for Venous Ulcer
NameACCKFocus
Manuka Honey323Locked
Diosmin 312Locked
Hesperidin211Locked
Hibiscus rosa-sinensis110Locked
Hyaluronic Acid110Locked
Marigold110Locked
Pycnogenol (Pine Bark)12Locked
3 Therapeutic Actions Researched for Venous Ulcer
NameACCKFocus
Photobiomodulation763Locked
Infrared Light220Locked
Hyperbaric Treatment213Locked

View the Evidence:
20 Abstracts with Venous Ulcer Research

[+]

Calendula officinalis extract is an effective treatment for venous leg ulcers.Dec 01, 2016

Pubmed Data : J Wound Care. 2016 Dec 2 ;25(12):732-739. PMID: 27974009
Article Published Date : Dec 01, 2016
Study Type : Human Study
Additional Links
Substances : Marigold
Diseases : Venous Ulcer, Wound Healing
Additional Keywords : Plant Extracts, Significant Treatment Outcome
[+]

Daflon, a form of micronized diosmin and hesperidin, improves the healing of venous leg ulcers. Sep 01, 2005

Pubmed Data : Angiology. 2005 Sep-Oct;56 Suppl 1:S33-9. PMID: 16193225
Article Published Date : Sep 01, 2005
Study Type : Human Study
Additional Links
Substances : Diosmin , Hesperidin
Diseases : Leg Ulcer, Venous Ulcer
[+]

Efficacy and safety of 4% Hibiscus rosa-sinensis leaf extract ointment as an adjunct treatment to compression stockings on the closure of venous leg ulcers.Aug 31, 2019

Pubmed Data : Wounds. 2019 Sep ;31(9):236-241. Epub 2019 Jun 30. PMID: 31298659
Article Published Date : Aug 31, 2019
Study Type : Human Study
Additional Links
Substances : Hibiscus rosa-sinensis
Diseases : Venous Ulcer, Wound Healing
Pharmacological Actions : Anti-Ulcer Agents
Additional Keywords : Plant Extracts
[+]

Efficacy and safety of a hyaluronic acid-containing cream in the treatment of chronic, venous, or mixed-origin leg ulcers.Oct 31, 2021

Pubmed Data : Wounds. 2021 Nov ;33(11):285-289. Epub 2021 Oct 5. PMID: 35025757
Article Published Date : Oct 31, 2021
Study Type : Human Study
Additional Links
Substances : Hyaluronic Acid
Diseases : Venous Ulcer, Wound Healing
Pharmacological Actions : Anti-Ulcer Agents
[+]

Improvement of wound healing by water-filtered infrared-A (wIRA) in patients with chronic venous stasis ulcers of the lower legs.Oct 20, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ger Med Sci. 2008 Oct 21 ;6:Doc11. Epub 2008 Oct 21. PMID: 19675738
Article Published Date : Oct 20, 2008
Study Type : Human Study
Additional Links
Diseases : Venous Ulcer, Wound Healing
Therapeutic Actions : Infrared Light, Photobiomodulation
[+]

Manuka honey fights serious infection caused by MRSAJun 01, 2008

Pubmed Data : J Wound Care. 2008 Jun;17(6):241-4, 246-7. PMID: 18666717
Article Published Date : Jun 01, 2008
Study Type : Human Study
Additional Links
Substances : Manuka Honey
Diseases : MRSA, Staphylococcus aureus: Methicillin-resistant (MRSA), Venous Ulcer
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Manuka honey is superior to standard hydrogel therapy in the treatment of sloughy venous ulcers.Feb 01, 2009

Pubmed Data : J Clin Nurs. 2009 Feb;18(3):466-74. Epub 2008 Aug 23. PMID: 18752540
Article Published Date : Feb 01, 2009
Study Type : Human Study
Additional Links
Substances : Manuka Honey
Diseases : Venous Ulcer
Additional Keywords : Superiority of Natural Substances versus Drugs
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PBM in addition to dressing may have multiple benefits on hard-to-heal venous leg ulcer.Dec 31, 2021

Pubmed Data : PLoS One. 2022 ;17(9):e0274023. Epub 2022 Sep 15. PMID: 36107964
Article Published Date : Dec 31, 2021
Study Type : Human Study
Additional Links
Diseases : Venous Ulcer
Therapeutic Actions : Photobiomodulation
[+]

PBMT with blue light was well-tolerated, safe, and efficacious in improving wound healing with an adjunct to standard treatment of chronic venous ulcers.Aug 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cureus. 2021 Sep ;13(9):e17703. Epub 2021 Sep 4. PMID: 34650877
Article Published Date : Aug 31, 2021
Study Type : Human Study
Additional Links
Diseases : Venous Ulcer
Therapeutic Actions : Photobiomodulation
[+]

Phototherapy improves healing of chronic venous ulcers.Jan 31, 2009

Pubmed Data : Photomed Laser Surg. 2009 Feb ;27(1):111-8. PMID: 19196110
Article Published Date : Jan 31, 2009
Study Type : Human Study
Additional Links
Diseases : Venous Ulcer, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

The effectiveness of hyperbaric oxygen therapy for healing chronic venous leg ulcers.Jun 30, 2018

Pubmed Data : Wound Repair Regen. 2018 Jul ;26(4):324-331. Epub 2018 Oct 19. PMID: 30129080
Article Published Date : Jun 30, 2018
Study Type : Human Study
Additional Links
Diseases : Venous Ulcer, Wound Healing
Therapeutic Actions : Hyperbaric Treatment
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The use of infrared laser therapy in the treatment of venous ulceration.Feb 28, 1990

Pubmed Data : Ann Vasc Surg. 1990 Mar ;4(2):179-81. PMID: 2310669
Article Published Date : Feb 28, 1990
Study Type : Human Study
Additional Links
Diseases : Venous Ulcer
Therapeutic Actions : Infrared Light, Photobiomodulation
[+]

Treatment of refractory venous stasis ulcers with autologous platelet-rich plasma and light-emitting diodes.Sep 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dermatolog Treat. 2013 Oct ;24(5):332-5. Epub 2013 Jun 27. PMID: 23738854
Article Published Date : Sep 30, 2013
Study Type : Human Study
Additional Links
Diseases : Venous Ulcer, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Combination treatment with light emitting diode and wound dressings in a patient with a venous leg ulcer.Feb 29, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Acta Dermatovenerol Alp Pannonica Adriat. 2020 Mar ;29(1):39-42. PMID: 32206822
Article Published Date : Feb 29, 2020
Study Type : Human: Case Report
Additional Links
Diseases : Venous Ulcer, Wound Healing
Therapeutic Actions : Photobiomodulation
[+]

Successful treatment of a venous leg ulcer with manuka honey: A case study.Dec 31, 2020

Pubmed Data : J Wound Ostomy Continence Nurs. 2021 Jan-Feb 01;48(1):79-82. PMID: 33427815
Article Published Date : Dec 31, 2020
Study Type : Human: Case Report
Additional Links
Substances : Manuka Honey
Diseases : Venous Ulcer
Pharmacological Actions : Anti-Ulcer Agents
[+]

Successful use of hyperbaric oxygen as adjunctive therapy for a nonhealing venous ulcer.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Case Rep Pulmonol. 2020 ;2020:4750375. Epub 2020 Feb 24. PMID: 32181042
Article Published Date : Dec 31, 2019
Study Type : Human: Case Report, Review
Additional Links
Diseases : Venous Ulcer
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Ulcer Agents
[+]

The results suggest that pycnogenol has an adjuvant effect on the healing of venous ulcers, similar to diosmin/hesperidin.Aug 09, 2016

Pubmed Data : Ann Vasc Surg. 2016 Aug 10. Epub 2016 Aug 10. PMID: 27521821
Article Published Date : Aug 09, 2016
Study Type : Animal Study
Additional Links
Substances : Pycnogenol (Pine Bark)
Diseases : Venous Ulcer
Pharmacological Actions : Anti-Ulcer Agents
[+]

A combination of micronized hesperidin and diosmin has therapeutic value in chronic venous insufficiency, venous ulcers and haemorrhoids.Jan 01, 2003

Pubmed Data : Drugs. 2003;63(1):71-100. PMID: 12487623
Article Published Date : Jan 01, 2003
Study Type : Review
Additional Links
Substances : Diosmin , Hesperidin
Diseases : Chronic Venous Insufficency, Hemorrhoids, Venous Ulcer
Pharmacological Actions : Anti-Inflammatory Agents
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Diosmin has a significant clinical effect on middle-sized vein-related trophic ulcers. Jan 01, 2006

Pubmed Data : Angiol Sosud Khir. 2006;12(3):53-60. PMID: 17641615
Article Published Date : Jan 01, 2006
Study Type : Review
Additional Links
Substances : Diosmin
Diseases : Chronic Venous Insufficency, Venous Ulcer
[+]

Calendula demonstrates profound therapeutic potential against venous leg ulcers.Jan 01, 2005

Pubmed Data : Int J Tissue React. 2005;27(3):101-6. PMID: 16372475
Article Published Date : Jan 01, 2005
Additional Links
Diseases : Venous Ulcer

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