Venous Ulcer

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7 Substances Researched for Venous Ulcer

Name	AC	CK
Manuka Honey	3	23
Diosmin	3	12
Hesperidin	2	11
Hibiscus rosa-sinensis	1	10
Hyaluronic Acid	1	10
Marigold	1	10
Pycnogenol (Pine Bark)	1	2

1 Therapeutic Actions Researched for Venous Ulcer

Name	AC	CK	Focus
Hyperbaric Treatment	2	13

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

View the Evidence:
13 Abstracts with Venous Ulcer Research

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Calendula officinalis extract is an effective treatment for venous leg ulcers.Dec 01, 2016

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Pubmed Data : J Wound Care. 2016 Dec 2 ;25(12):732-739. PMID: 27974009

Article Published Date : Dec 01, 2016

Study Type : Human Study

Additional Links

Substances : Marigold

Diseases : Venous Ulcer, Wound Healing

Additional Keywords : Plant Extracts, Significant Treatment Outcome

[+]

Daflon, a form of micronized diosmin and hesperidin, improves the healing of venous leg ulcers. Sep 01, 2005

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Pubmed Data : Angiology. 2005 Sep-Oct;56 Suppl 1:S33-9. PMID: 16193225

Article Published Date : Sep 01, 2005

Study Type : Human Study

Additional Links

Substances : Diosmin , Hesperidin

Diseases : Leg Ulcer, Venous Ulcer

[+]

Efficacy and safety of 4% Hibiscus rosa-sinensis leaf extract ointment as an adjunct treatment to compression stockings on the closure of venous leg ulcers.Aug 31, 2019

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Pubmed Data : Wounds. 2019 Sep ;31(9):236-241. Epub 2019 Jun 30. PMID: 31298659

Article Published Date : Aug 31, 2019

Study Type : Human Study

Additional Links

Substances : Hibiscus rosa-sinensis

Diseases : Venous Ulcer, Wound Healing

Pharmacological Actions : Anti-Ulcer Agents

Additional Keywords : Plant Extracts

[+]

Efficacy and safety of a hyaluronic acid-containing cream in the treatment of chronic, venous, or mixed-origin leg ulcers.Oct 31, 2021

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Pubmed Data : Wounds. 2021 Nov ;33(11):285-289. Epub 2021 Oct 5. PMID: 35025757

Article Published Date : Oct 31, 2021

Study Type : Human Study

Additional Links

Substances : Hyaluronic Acid

Diseases : Venous Ulcer, Wound Healing

Pharmacological Actions : Anti-Ulcer Agents

[+]

Manuka honey fights serious infection caused by MRSAJun 01, 2008

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Pubmed Data : J Wound Care. 2008 Jun;17(6):241-4, 246-7. PMID: 18666717

Article Published Date : Jun 01, 2008

Study Type : Human Study

Additional Links

Substances : Manuka Honey

Diseases : MRSA, Staphylococcus aureus: Methicillin-resistant (MRSA), Venous Ulcer

[+]

Manuka honey is superior to standard hydrogel therapy in the treatment of sloughy venous ulcers.Feb 01, 2009

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Pubmed Data : J Clin Nurs. 2009 Feb;18(3):466-74. Epub 2008 Aug 23. PMID: 18752540

Article Published Date : Feb 01, 2009

Study Type : Human Study

Additional Links

Substances : Manuka Honey

Diseases : Venous Ulcer

Additional Keywords : Superiority of Natural Substances versus Drugs

[+]

The effectiveness of hyperbaric oxygen therapy for healing chronic venous leg ulcers.Jun 30, 2018

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Pubmed Data : Wound Repair Regen. 2018 Jul ;26(4):324-331. Epub 2018 Oct 19. PMID: 30129080

Article Published Date : Jun 30, 2018

Study Type : Human Study

Additional Links

Diseases : Venous Ulcer, Wound Healing

Therapeutic Actions : Hyperbaric Treatment

[+]

Successful treatment of a venous leg ulcer with manuka honey: A case study.Dec 31, 2020

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Pubmed Data : J Wound Ostomy Continence Nurs. 2021 Jan-Feb 01;48(1):79-82. PMID: 33427815

Article Published Date : Dec 31, 2020

Study Type : Human: Case Report

Additional Links

Substances : Manuka Honey

Diseases : Venous Ulcer

Pharmacological Actions : Anti-Ulcer Agents

[+]

Successful use of hyperbaric oxygen as adjunctive therapy for a nonhealing venous ulcer.Dec 31, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Case Rep Pulmonol. 2020 ;2020:4750375. Epub 2020 Feb 24. PMID: 32181042

Article Published Date : Dec 31, 2019

Study Type : Human: Case Report, Review

Additional Links

Diseases : Venous Ulcer

Therapeutic Actions : Hyperbaric Treatment

Pharmacological Actions : Anti-Ulcer Agents

[+]

The results suggest that pycnogenol has an adjuvant effect on the healing of venous ulcers, similar to diosmin/hesperidin.Aug 09, 2016

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Pubmed Data : Ann Vasc Surg. 2016 Aug 10. Epub 2016 Aug 10. PMID: 27521821

Article Published Date : Aug 09, 2016

Study Type : Animal Study

Additional Links

Substances : Pycnogenol (Pine Bark)

Diseases : Venous Ulcer

Pharmacological Actions : Anti-Ulcer Agents

[+]

A combination of micronized hesperidin and diosmin has therapeutic value in chronic venous insufficiency, venous ulcers and haemorrhoids.Jan 01, 2003

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Pubmed Data : Drugs. 2003;63(1):71-100. PMID: 12487623

Article Published Date : Jan 01, 2003

Study Type : Review

Additional Links

Substances : Diosmin , Hesperidin

Diseases : Chronic Venous Insufficency, Hemorrhoids, Venous Ulcer

Pharmacological Actions : Anti-Inflammatory Agents

[+]

Diosmin has a significant clinical effect on middle-sized vein-related trophic ulcers. Jan 01, 2006

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Pubmed Data : Angiol Sosud Khir. 2006;12(3):53-60. PMID: 17641615

Article Published Date : Jan 01, 2006

Study Type : Review

Additional Links

Substances : Diosmin

Diseases : Chronic Venous Insufficency, Venous Ulcer

[+]

Calendula demonstrates profound therapeutic potential against venous leg ulcers.Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Int J Tissue React. 2005;27(3):101-6. PMID: 16372475

Article Published Date : Jan 01, 2005

Additional Links

Diseases : Venous Ulcer

Research Articles 13
Cumulative Knowledge Score 21
Overall Research Rating GOOD

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 13 Abstracts with Venous Ulcer Research

Limited to Members Only

Currently Available Sorting Options

Calendula officinalis extract is an effective treatment for venous leg ulcers.Dec 01, 2016

Daflon, a form of micronized diosmin and hesperidin, improves the healing of venous leg ulcers. Sep 01, 2005

Efficacy and safety of 4% Hibiscus rosa-sinensis leaf extract ointment as an adjunct treatment to compression stockings on the closure of venous leg ulcers.Aug 31, 2019

Efficacy and safety of a hyaluronic acid-containing cream in the treatment of chronic, venous, or mixed-origin leg ulcers.Oct 31, 2021

Manuka honey fights serious infection caused by MRSAJun 01, 2008

Manuka honey is superior to standard hydrogel therapy in the treatment of sloughy venous ulcers.Feb 01, 2009

The effectiveness of hyperbaric oxygen therapy for healing chronic venous leg ulcers.Jun 30, 2018

Successful treatment of a venous leg ulcer with manuka honey: A case study.Dec 31, 2020

Successful use of hyperbaric oxygen as adjunctive therapy for a nonhealing venous ulcer.Dec 31, 2019

The results suggest that pycnogenol has an adjuvant effect on the healing of venous ulcers, similar to diosmin/hesperidin.Aug 09, 2016

A combination of micronized hesperidin and diosmin has therapeutic value in chronic venous insufficiency, venous ulcers and haemorrhoids.Jan 01, 2003

Diosmin has a significant clinical effect on middle-sized vein-related trophic ulcers. Jan 01, 2006

Calendula demonstrates profound therapeutic potential against venous leg ulcers.Jan 01, 2005

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Venous Ulcer

View the Evidence:
13 Abstracts with Venous Ulcer Research