Vitiligo

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31 Substances Researched for Vitiligo
NameACCKFocus
Piperine322Locked
Ginkgo biloba321Locked
EGCG (Epigallocatechin gallate)215Locked
Curcumin413Locked
Folic Acid 211Locked
Turmeric211Locked
Vitamin D211Locked
Capsaicin110Locked
Catechin 110Locked
Glycyrrhizin110Locked
Homeopathic Medicine: All110Locked
Nigella sativa (aka Black Seed)110Locked
Polypodium leucotomos110Locked
Silibinin110Locked
Vitamin B-12110Locked
Vitamin C110Locked
Apigenin15Locked
Harmine15Locked
Kaempferol15Locked
Black Pepper34Locked
Babchi12Locked
Berberine12Locked
Goji12Locked
Tanshinone IIA12Locked
6-Shogaol11Locked
Flavonoids11Locked
Green Tea11Locked
Malytea Scurfpea11Locked
Paeoniflorin11Locked
Piperidines11Locked
Quercetin11Locked
4 Therapeutic Actions Researched for Vitiligo
NameACCKFocus
Sunlight Exposure: UVB Light770Locked
Light Therapy440Locked
Integrative Medicine110Locked
Photobiomodulation55Locked
1 Problematic Actions Researched for Vitiligo
NameACCKFocus
Vaccination: All12Locked

View the Evidence:
49 Abstracts with Vitiligo Research

[+]

1,25-dihydroxyvitamin D3 provides benefits in vitiligo.Nov 05, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2023 Nov 6 ;15(21). Epub 2023 Nov 6. PMID: 37960350
Article Published Date : Nov 05, 2023
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Vitiligo
Pharmacological Actions : Immunomodulatory
[+]

Curcumin and capsaicin might represent an alternative approach to protect against vitiligo progression.Jan 19, 2010

Pubmed Data : Antioxid Redox Signal. 2010 Jan 19. Epub 2010 Jan 19. PMID: 20085492
Article Published Date : Jan 19, 2010
Study Type : Human Study
Additional Links
Substances : Capsaicin, Curcumin
Diseases : Vitiligo
[+]

Effectiveness of topical Nigella sativa for vitiligo treatment.Apr 24, 2019

Pubmed Data : Dermatol Ther. 2019 Apr 25:e12949. Epub 2019 Apr 25. PMID: 31025474
Article Published Date : Apr 24, 2019
Study Type : Human Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Vitiligo
[+]

Gingko biloba is effective in slowing the progression of vitiligo.May 01, 2003

Pubmed Data : Clin Exp Dermatol. 2003 May;28(3):285-7. PMID: 12780716
Article Published Date : May 01, 2003
Study Type : Human Study
Additional Links
Substances : Ginkgo biloba
Diseases : Vitiligo
[+]

Ginkgo biloba halts the progression of vitilgo, and may stimulate repigmentation in some patients.Jan 01, 2011

Pubmed Data : BMC Complement Altern Med. 2011 ;11:21. Epub 2011 Mar 15. PMID: 21406109
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Substances : Ginkgo biloba
Diseases : Vitiligo
[+]

Glycyrrhizin and ultraviolet B light therapy improved active-stage generalized vitiligo.Jul 24, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Braz J Med Biol Res. 2016 Jul 25 ;49(8). PMID: 27464024
Article Published Date : Jul 24, 2016
Study Type : Human Study
Additional Links
Substances : Glycyrrhizin
Diseases : Vitiligo
Therapeutic Actions : Integrative Medicine, Light Therapy
[+]

Homeopathy may be effective in the early stages of vitiligo.Dec 01, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Case Rep. 2017 Dec 2 ;18:1276-1283. Epub 2017 Dec 2. PMID: 29196612
Article Published Date : Dec 01, 2017
Study Type : Human Study
Additional Links
Substances : Homeopathic Medicine: All
Diseases : Vitiligo
[+]

Low-dose baricitinib plus narrow-band ultraviolet B for the treatment of progressive non-segmental vitiligo.Dec 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pigment Cell Melanoma Res. 2025 Jan ;38(1):e13209. Epub 2024 Oct 23. PMID: 39441554
Article Published Date : Dec 31, 2024
Study Type : Human Study
Additional Links
Diseases : Vitiligo
Therapeutic Actions : Sunlight Exposure: UVB Light
[+]

Narrow-band ultraviolet B is a useful and well-tolerated treatment for vitiligo.May 31, 2001

Pubmed Data : J Am Acad Dermatol. 2001 Jun ;44(6):999-1003. PMID: 11369913
Article Published Date : May 31, 2001
Study Type : Human Study
Additional Links
Diseases : Vitiligo
Therapeutic Actions : Sunlight Exposure: UVB Light
[+]

NB-UVB plus oral Polypodium leucotomos extract display higher efficacy than NB-UVB alone in patients with vitiligo.Jan 11, 2021

Pubmed Data : Dermatol Ther. 2021 Jan 12:e14776. Epub 2021 Jan 12. PMID: 33433041
Article Published Date : Jan 11, 2021
Study Type : Human Study
Additional Links
Substances : Polypodium leucotomos
Diseases : Vitiligo
Therapeutic Actions : Light Therapy
[+]

No association was observed between the number of NB-UVB treatments and carcinogenesis in any study group.Dec 31, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Photodermatol Photoimmunol Photomed. 2024 Jan ;40(1):e12936. Epub 2023 Dec 7. PMID: 38059681
Article Published Date : Dec 31, 2023
Study Type : Human Study
Additional Links
Diseases : Psoriasis, Skin Cancer, Vitiligo
Therapeutic Actions : Sunlight Exposure: UVB Light
[+]

Once-weekly targeted ultraviolet B phototherapy appears to be as efficacious as the twice-weekly regimen in vitiligo.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Dermatol Venereol Leprol. 2015 ;81(6):600-5. PMID: 26515839
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Vitiligo
Therapeutic Actions : Sunlight Exposure: UVB Light
[+]

Simultaneous use of narrowband ultraviolet B and topical piperine has a remarkable effect on treatment of vitiligo.May 20, 2018

Pubmed Data : Phytother Res. 2018 May 21. Epub 2018 May 21. PMID: 29781089
Article Published Date : May 20, 2018
Study Type : Human Study
Additional Links
Substances : Piperine
Diseases : Vitiligo
Therapeutic Actions : Light Therapy
[+]

The effect of vitamin C on oxidative stress indices and skin regimentation of vitiligo patients.Oct 31, 2023

Pubmed Data : Arch Dermatol Res. 2023 Nov ;315(9):2655-2660. Epub 2023 Aug 22. PMID: 37606744
Article Published Date : Oct 31, 2023
Study Type : Human Study
Additional Links
Substances : Vitamin C
Diseases : Oxidative Stress, Vitiligo
Pharmacological Actions : Antioxidants
[+]

This study showed that probably Silybum marianum is a good choice for patients with vitiligo.Apr 01, 2019

Pubmed Data : J Dermatolog Treat. 2019 Apr 2:1-5. Epub 2019 Apr 2. PMID: 30935260
Article Published Date : Apr 01, 2019
Study Type : Human Study
Additional Links
Substances : Silibinin
Diseases : Vitiligo
[+]

Topical epigallocatechin-3-gallate in the treatment of vitiligo.Jul 31, 2021

Pubmed Data : Australas J Dermatol. 2021 Aug ;62(3):e404-e407. Epub 2021 May 28. PMID: 34046892
Article Published Date : Jul 31, 2021
Study Type : Human Study
Additional Links
Substances : Catechin , EGCG (Epigallocatechin gallate)
Diseases : Vitiligo
Pharmacological Actions : Dermatologic Agents
[+]

Treatment outcome and persistence of repigmentation from narrow-band ultraviolet B phototherapy in vitiligo.Oct 31, 2019

Pubmed Data : J Dermatolog Treat. 2019 Nov ;30(7):691-696. Epub 2018 Dec 5. PMID: 30474443
Article Published Date : Oct 31, 2019
Study Type : Human Study
Additional Links
Diseases : Vitiligo
Therapeutic Actions : Sunlight Exposure: UVB Light
[+]

Turmeric cream can be used as an alternative remedy or adjuvant therapy in mild to moderate vitiligo lesions.Jan 31, 2022

Pubmed Data : J Cosmet Dermatol. 2022 Feb 1. Epub 2022 Feb 1. PMID: 35104042
Article Published Date : Jan 31, 2022
Study Type : Human Study
Additional Links
Substances : Turmeric
Diseases : Vitiligo
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

UVB is an effective modality for treatment of vitiligo.Jun 30, 2023

Pubmed Data : Photodermatol Photoimmunol Photomed. 2023 Jul ;39(4):357-363. Epub 2022 Dec 7. PMID: 36419200
Article Published Date : Jun 30, 2023
Study Type : Human Study
Additional Links
Diseases : Vitiligo
Therapeutic Actions : Sunlight Exposure: UVB Light
[+]

UVB-IPL phototherapy seems to be effective and well-tolerated in non-segmental vitiligo.Dec 31, 2013

Pubmed Data : Eur J Dermatol. 2014 ;24(5):551-9. PMID: 25445089
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Diseases : Vitiligo
Therapeutic Actions : Sunlight Exposure: UVB Light
[+]

Vitamin B12, folic acid and sunlight appear an effective therapy in Vitiligo. Nov 01, 1997

Pubmed Data : Acta Derm Venereol. 1997 Nov;77(6):460-2. PMID: 9394983
Article Published Date : Nov 01, 1997
Study Type : Human Study
Additional Links
Substances : Folic Acid , Vitamin B-12
Diseases : Vitiligo
[+]

Vitiligo treated with combined piperine-based topical treatment and narrowband ultraviolet B therapyFeb 24, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Diagnostics (Basel). 2024 Feb 25 ;14(5). Epub 2024 Feb 25. PMID: 38472966
Article Published Date : Feb 24, 2024
Study Type : Human Study
Additional Links
Substances : Piperine
Diseases : Vitiligo
Therapeutic Actions : Light Therapy
[+]

Apigenin protects human melanocytes against oxidative damage by activation of the Nrf2 pathway.Jan 17, 2020

Pubmed Data : Cell Stress Chaperones. 2020 Jan 18. Epub 2020 Jan 18. PMID: 31953635
Article Published Date : Jan 17, 2020
Study Type : Human In Vitro
Additional Links
Substances : Apigenin
Diseases : Vitiligo
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Harmine and Kaempferol treatment enhances NFATC1 and FOXP3 mediated regulatory T-cells' suppressive capacity in generalized vitiligo.Nov 30, 2023

Pubmed Data : Int Immunopharmacol. 2023 Dec ;125(Pt B):111174. Epub 2023 Nov 9. PMID: 37951194
Article Published Date : Nov 30, 2023
Study Type : Human In Vitro
Additional Links
Substances : Harmine, Kaempferol
Diseases : Vitiligo
[+]

These results provide new evidence for the effectiveness of EGCG in vitiligo treatment.Sep 03, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Pharm Bull. 2015 Sep 4. Epub 2015 Sep 4. PMID: 26345342
Article Published Date : Sep 03, 2015
Study Type : Human In Vitro
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Vitiligo
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Mechanisms of action of Lycium barbarum polysaccharide in protecting against vitiligo.Nov 30, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharm Biol. 2023 Dec ;61(1):281-287. PMID: 36655287
Article Published Date : Nov 30, 2023
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Vitiligo
Additional Keywords : Polysaccharides
[+]

New insights in vitiligo treatments using bioactive compounds from Piper nigrum.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Feb ;17(2):1039-1044. Epub 2018 Nov 16. PMID: 30679971
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Black Pepper
Diseases : Vitiligo
[+]

Novel berberine-loaded hyalurosomes as a promising nanodermatological treatment for vitiligo.Jan 28, 2022

Pubmed Data : Int J Pharm. 2022 Jan 29:121523. Epub 2022 Jan 29. PMID: 35104596
Article Published Date : Jan 28, 2022
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Berberine
Diseases : Vitiligo
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Preliminary testing of cancer vaccines caused mice to develop vitiligo.Feb 15, 2004

Pubmed Data : Cancer Res. 2004 Feb 15 ;64(4):1509-14. PMID: 14973051
Article Published Date : Feb 15, 2004
Study Type : Animal Study
Additional Links
Diseases : Vaccine-induced Toxicity , Vitiligo
Anti Therapeutic Actions : Vaccination: All
[+]

Seed powder of Psoralea corylifolia could be an effective monotherapy for small circular white lesions of vitiligo.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Drug Des Devel Ther. 2016 ;10:3805-3816. Epub 2016 Nov 22. PMID: 27920496
Article Published Date : Dec 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Babchi
Diseases : Vitiligo
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Tanshinone IIA alleviates vitiligo by suppressing AKT mediated CD8 + T cells activation.Aug 03, 2021

Pubmed Data : Dermatol Ther. 2021 Aug 4:e15086. Epub 2021 Aug 4. PMID: 34350676
Article Published Date : Aug 03, 2021
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Vitiligo
Pharmacological Actions : Immunomodulatory
[+]

Topical treatment with piperine improves the treatment response to UV irradiation in the mouse model of Vitiligo.May 01, 2008

Pubmed Data : Br J Dermatol. 2008 May;158(5):941-50. Epub 2008 Feb 16. PMID:18284389
Article Published Date : May 01, 2008
Study Type : Animal Study
Additional Links
Substances : Piperine
Diseases : Vitiligo
[+]

6-shogaol protects human melanocytes against oxidative stress through activation of the Nrf2-antioxidant response element signalling pathway. May 15, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 May 16 ;21(10). Epub 2020 May 16. PMID: 32429495
Article Published Date : May 15, 2020
Study Type : In Vitro Study
Additional Links
Substances : 6-Shogaol
Diseases : Skin Diseases, Vitiligo
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

A combination of green tea, quercetin and folate may contribute to reducing melanocyte oxidative stress in Vitiligo. Nov 01, 2005

Pubmed Data : Arch Pharm Res. 2005 Nov;28(11):1251-6. PMID: 16350851
Article Published Date : Nov 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid , Green Tea, Quercetin
Diseases : Vitiligo
[+]

A review of the skin regenerative potentials of Curcumin.Dec 31, 2012

Pubmed Data : Biofactors. 2013 Jan-Feb;39(1):141-9. Epub 2013 Jan 11. PMID: 23315856
Article Published Date : Dec 31, 2012
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Psoriasis, Skin Cancer, Vitiligo, Wound Healing
Pharmacological Actions : Antineoplastic Agents, Chemopreventive, Regenerative
[+]

Afzelin could be used for the prevention of oxidative stress-induced damage in melanocytes and its potential as a therapeutic agent for vitiligo.Dec 31, 2016

Pubmed Data : Exp Dermatol. 2017 09 ;26(9):764-770. Epub 2017 Apr 11. PMID: 27992083
Article Published Date : Dec 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Vitiligo
Pharmacological Actions : Antioxidants, Catalase Up-Regulation, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Black pepper has melanocyte modulating activity, confirming its traditional use for vitiligo. Apr 01, 2007

Pubmed Data : J Pharm Pharmacol. 2007 Apr;59(4):529-36. PMID: 17430636
Article Published Date : Apr 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Black Pepper
Diseases : Vitiligo
Pharmacological Actions : Antiproliferative
Additional Keywords : Plant Extracts, Science Confirms Tradition
[+]

Ginkgo biloba extract protects human melanocytes from H2O2-induced oxidative stress by activating Nrf2.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cell Mol Med. 2019 Aug ;23(8):5193-5199. Epub 2019 May 31. PMID: 31148371
Article Published Date : Jul 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Ginkgo biloba
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress, Vitiligo
Pharmacological Actions : Antioxidants, Nrf2 activation
[+]

Helium-neon laser irradiation stimulates migration and proliferation in melanocytes and induces repigmentation in segmental-type vitiligo.Dec 31, 2002

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Invest Dermatol. 2003 Jan ;120(1):56-64. PMID: 12535198
Article Published Date : Dec 31, 2002
Study Type : In Vitro Study
Additional Links
Diseases : Vitiligo
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Proliferative
[+]

If UVA radiation is used with piperine in the treatment of vitiligo, application of the compound and irradiation should be staggered to minimize photoisomerization.Nov 01, 2006

Pubmed Data : Photochem Photobiol. 2006 Nov-Dec;82(6):1541-8. PMID: 17387768
Article Published Date : Nov 01, 2006
Study Type : In Vitro Study
Additional Links
Substances : Black Pepper, Piperidines
Diseases : Vitiligo
Pharmacological Actions : Antiproliferative
[+]

Low-energy helium-neon laser induces locomotion of the immature melanoblasts and promotes melanogenesis of the more differentiated melanoblasts.Aug 31, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Invest Dermatol. 2006 Sep ;126(9):2119-26. Epub 2006 May 11. PMID: 16691191
Article Published Date : Aug 31, 2006
Study Type : In Vitro Study
Additional Links
Diseases : Vitiligo
Therapeutic Actions : Photobiomodulation
[+]

Low-energy helium-neon laser induces melanocyte proliferation via interaction with type IV collagen: visible light as a therapeutic option for vitiligo.Jul 31, 2009

Pubmed Data : Br J Dermatol. 2009 Aug ;161(2):273-80. Epub 2009 Apr 30. PMID: 19438447
Article Published Date : Jul 31, 2009
Study Type : In Vitro Study
Additional Links
Diseases : Vitiligo
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Proliferative
[+]

Low-energy helium-neon laser therapy induces repigmentation and improves the abnormalities of cutaneous microcirculation in segmental-type vitiligo lesions.Mar 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Kaohsiung J Med Sci. 2008 Apr ;24(4):180-9. PMID: 18424354
Article Published Date : Mar 31, 2008
Study Type : In Vitro Study
Additional Links
Diseases : Vitiligo
Therapeutic Actions : Photobiomodulation
Additional Keywords : Skin Rejuvenation
[+]

Malytea Scurfpea fruit appears to be beneficial in the treatment of Vitiligo lesions. Apr 01, 2004

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2004 Apr;29(4):346-9. PMID: 15706874
Article Published Date : Apr 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Malytea Scurfpea
Diseases : Vitiligo
[+]

Mechanisms of repigmentation induced by photobiomodulation therapy in vitiligo.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Dermatol. 2019 Feb ;28 Suppl 1:10-14. PMID: 30698884
Article Published Date : Jan 31, 2019
Study Type : Review
Additional Links
Diseases : Vitiligo
Therapeutic Actions : Photobiomodulation
Pharmacological Actions : Proliferative
[+]

Therapeutic roles of curcumin: lessons learned from clinical trials.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : AAPS J. 2013 Jan ;15(1):195-218. Epub 2012 Nov 10. PMID: 23143785
Article Published Date : Dec 31, 2012
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Arthritis, Atherosclerosis, Cancers: All, Cardiovascular Diseases, Crohn's Disease, Diabetic Nephropathy, Gastric Ulcer, Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Oral Lichen Planus, Ulcerative Colitis, Uveitis, Vitiligo
[+]

There is early evidence that turmeric/curcumin products and supplements, both oral and topical, may provide therapeutic benefits for skin health.May 22, 2016

Pubmed Data : Phytother Res. 2016 May 23. Epub 2016 May 23. PMID: 27213821
Article Published Date : May 22, 2016
Study Type : Review
Additional Links
Substances : Curcumin, Turmeric
Diseases : Acne, Alopecia, Atopic Dermatitis, Oral Lichen Planus, Pruritus, Psoriasis, Radiodermatitis, Vitiligo
[+]

These results suggest a potential therapeutic application of paeoniflorin on vitiligo.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2020 ;11:536. Epub 2020 Apr 28. PMID: 32410998
Article Published Date : Dec 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Paeoniflorin
Diseases : Hydrogen Peroxide Induced Toxicity, Oxidative Stress, Vitiligo
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Nrf2 activation
[+]

Vitamin D may have a therapeutic role in vitiligo. May 01, 2009

Pubmed Data : Med Res Rev. 2009 May;29(3):514-46. PMID: 19241402
Article Published Date : May 01, 2009
Study Type : Commentary
Additional Links
Substances : Vitamin D
Diseases : Vitiligo

Copyright: rob3000 / 123RF Stock Photo

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