Whooping Cough

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10 Substances Researched for Whooping Cough
NameACCKFocus
Caffeine13Locked
Homeopathic Medicine: All13Locked
Black Tea12Locked
Catechin 12Locked
Coffee12Locked
Green Tea12Locked
Lactobacilius bulgaricus12Locked
Oak12Locked
Pine Buds12Locked
St. Johns Wort12Locked
1 Problem Substances Researched for Whooping Cough
NameACCKFocus
Antibiotics120Locked
5 Problematic Actions Researched for Whooping Cough
NameACCKFocus
Vaccination: Pertussis19107Locked
Vaccination: Diphtheria-Pertussis-Tetanus955Locked
Vaccination: All551Locked
Vaccination: Tetanus110Locked
Vaccination: DPT11Locked

View the Evidence:
30 Abstracts with Whooping Cough Research

[+]

Antibiotics are effective in eliminating B. pertussis from patients with the disease, rendering them non-infectious, but do not alter the subsequent clinical course of the illness.Dec 31, 2004

Pubmed Data : Cochrane Database Syst Rev. 2005(1):CD004404. Epub 2005 Jan 25. PMID: 15674946
Article Published Date : Dec 31, 2004
Study Type : Meta Analysis
Additional Links
Diseases : Pertussis, Whooping Cough
Problem Substances : Antibiotics
[+]

Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015.Jan 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Euro Surveill. 2019 Feb ;24(7). PMID: 30782265
Article Published Date : Jan 31, 2019
Study Type : Meta Analysis
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

The risk of adverse events from the pertussis vaccine outweighed the risk of pertussis infection.Jan 01, 1985

Pubmed Data : Dev Biol Stand. 1985;61:395-405. PMID: 3835080
Article Published Date : Jan 01, 1985
Study Type : Meta Analysis
Additional Links
Diseases : Vaccine-induced Toxicity , Whooping Cough
Anti Therapeutic Actions : Vaccination: All, Vaccination: Pertussis
[+]

"Primary infections with either B. pertussis or Bordetella parapertussis stimulated a vigorous antibody response to ACT. In contrast, patients in whom DTP and DTaP vaccines failed had minimal ACT antibody responses."Feb 14, 2004

Pubmed Data : Clin Infect Dis. 2004 Feb 15 ;38(4):502-7. Epub 2004 Jan 29. PMID: 14765342
Article Published Date : Feb 14, 2004
Study Type : Human Study
Additional Links
Diseases : Parapertussis, Whooping Cough
Additional Keywords : Vaccine Failure
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

Environmental and nutritional factors modulate children's response to pertussis following natural infection or by vaccination.Jun 04, 2014

Pubmed Data : Vaccine. 2014 Jun 5 ;32(27):3431-7. Epub 2014 Apr 14. PMID: 24726248
Article Published Date : Jun 04, 2014
Study Type : Human Study
Additional Links
Diseases : Whooping Cough
Additional Keywords : Environmental Factors, Nutritional Factors, Reduced Disease Severity
[+]

Neurotoxicity from pertussis infection may be casually related to the pathogenesis of Parkinson's disease.Dec 01, 1996

Pubmed Data : Int J Epidemiol. 1996 Dec;25(6):1301-11. PMID: 9027539
Article Published Date : Dec 01, 1996
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease, Pertussis, Whooping Cough
Additional Keywords : Diseases that are Linked
[+]

Pertussis epidemic despite high levels of vaccination coverage with acellular pertussis vaccine.Nov 07, 2013

Article Published Date : Nov 07, 2013
Study Type : Human Study
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus
[+]

Polymorphisms in the VDR gene may affect immune activation and the clinical outcome of B. pertussis infection.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(2):e0149576. Epub 2016 Feb 19. PMID: 26894582
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Diseases : Pertussis, Whooping Cough
Additional Keywords : Genomic Variation
[+]

Since the 1993 pertussis epidemic in Cincinnati occurred primarily among children who had been appropriately immunized, it is clear that the whole-cell pertussis vaccine failed to give full protection against the disease.Jul 07, 1994

Pubmed Data : N Engl J Med. 1994 Jul 7;331(1):16-21. PMID: 8202096
Article Published Date : Jul 07, 1994
Study Type : Human Study
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis
[+]

This study demonstrated the differences between natural B. pertussis immune response and vaccine induced immune response. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Immunol. 2015 ;16:40. Epub 2015 Jul 1. PMID: 26129684
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Whooping Cough
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis
[+]

Vaccinated children and adults may serve as reservoirs for silent pertussis infection and become potential transmitters to unprotected infants.Sep 01, 2000

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Emerg Infect Dis. 2000 Sep-Oct;6(5):526-9. PMID: 10998384
Article Published Date : Sep 01, 2000
Study Type : Human Study
Additional Links
Diseases : Pertussis, Vaccine-induced Toxicity , Whooping Cough
Additional Keywords : Reservoirs For Infection
Anti Therapeutic Actions : Vaccination: All, Vaccination: Pertussis
[+]

Vaccinated siblings are important pertussis sources in infants 6 months of age and under.Sep 29, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Commun Dis Intell Q Rep. 2014 Sep 30 ;38(3):E195-200. Epub 2014 Sep 30. PMID: 25391405
Article Published Date : Sep 29, 2014
Study Type : Human Study
Additional Links
Diseases : Whooping Cough
Additional Keywords : Vaccine Shedding
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus
[+]

Vaccinating mothers with TdaP postpartum is not sufficient to protect infants younger than 6 months from pertussis illness.Nov 10, 2011

Pubmed Data : Clin Infect Dis. 2011 Nov 10. Epub 2011 Nov 10. PMID: 22075790
Article Published Date : Nov 10, 2011
Study Type : Human Study
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis, Vaccination: Tetanus
[+]

A case report of a 5-year-old, fully immunized boy with PCR proven consecutive B. pertussis and B. parapertussis infections.Jul 05, 2016

Pubmed Data : Pediatr Infect Dis J. 2016 Jul 6. Epub 2016 Jul 6. PMID: 27391699
Article Published Date : Jul 05, 2016
Study Type : Human: Case Report
Additional Links
Diseases : Parapertussis, Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

Caffeine might improve outcomes in pertussis by preventing apnoea and decreasing pulmonary complications.Mar 27, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMJ Case Rep. 2018 Mar 28 ;2018. Epub 2018 Mar 28. PMID: 29592985
Article Published Date : Mar 27, 2018
Study Type : Human: Case Report
Additional Links
Substances : Caffeine
Diseases : Pertussis, Whooping Cough
Additional Keywords : Risk Reduction
[+]

Homeopathic medicines can alleviate the intensity or reduce the duration of whooping cough.Oct 01, 2017

Pubmed Data : Altern Ther Health Med. 2017 Oct 2. Epub 2017 Oct 2. PMID: 28987075
Article Published Date : Oct 01, 2017
Study Type : Human: Case Report
Additional Links
Substances : Homeopathic Medicine: All
Diseases : Whooping Cough
[+]

Baboons vaccinated with acellular pertussis were protected from severe pertussis-associated symptoms but not from colonization, did not clear the infection faster than naïve animals, and readily transmitted B. pertussis to unvaccinated contacts.Jan 14, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 2014 Jan 14 ;111(2):787-92. Epub 2013 Nov 25. PMID: 24277828
Article Published Date : Jan 14, 2014
Study Type : Animal Study
Additional Links
Diseases : Whooping Cough
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis
[+]

Bordetella pertussis strains that are pertactin negative have a greater ability of to colonize acellular vaccine immunised mice.Oct 01, 2015

Pubmed Data : Vaccine. 2015 Oct 2. Epub 2015 Oct 2. PMID: 26432908
Article Published Date : Oct 01, 2015
Study Type : Animal Study
Additional Links
Diseases : Whooping Cough
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

Green tea (EGCG), black tea and coffee may protect against Bordetella pertussis infection.Dec 01, 2006

Pubmed Data : Chem Biol Interact. 2006 Dec 1;164(1-2):102-14. Epub 2006 Sep 16. PMID: 1402092
Article Published Date : Dec 01, 2006
Study Type : Animal Study
Additional Links
Substances : Black Tea, Catechin , Coffee, Green Tea
Diseases : Pertussis, Whooping Cough
Pharmacological Actions : Anti-Bacterial Agents
[+]

Lactobacillus bulgaricus contains a substance which may improve immunogenicity and reduce the toxicity of pertussis vaccination (whooping cough vaccine).Jan 01, 1986

Pubmed Data : Zh Mikrobiol Epidemiol Immunobiol. 1986 Jan;(1):62-5. PMID: 3705806
Article Published Date : Jan 01, 1986
Study Type : Animal Study
Additional Links
Substances : Lactobacilius bulgaricus
Diseases : Pertussis, Whooping Cough
Additional Keywords : Vaccine Side Effect Attenuation
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

Natural plant extracts from oak bark, St. john's work leaves and pine buds may have therapeutic activity in supporting natural immunity from Staphylococcus aureus and Bordetella pertussis.Apr 01, 1986

Pubmed Data : Zh Mikrobiol Epidemiol Immunobiol. 1986 Apr(4):71-5. PMID: 3012909
Article Published Date : Apr 01, 1986
Study Type : Animal Study
Additional Links
Substances : Oak, Pine Buds, St. Johns Wort
Diseases : Pertussis, Whooping Cough
Pharmacological Actions : Immunomodulatory
Additional Keywords : Plant Extracts
[+]

All children who were primed by DTaP vaccines will be more susceptible to pertussis throughout their lifetimes.Feb 21, 2019

Pubmed Data : J Pediatric Infect Dis Soc. 2019 Feb 22. Epub 2019 Feb 22. PMID: 30793754
Article Published Date : Feb 21, 2019
Study Type : Review
Additional Links
Diseases : Whooping Cough
Additional Keywords : Increased Risk
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis
[+]

Asymptomatic transmission is the most parsimonious explanation for many of the observations surrounding the resurgence of B. pertussis in the US and UK.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Med. 2015 ;13:146. Epub 2015 Jun 24. PMID: 26103968
Article Published Date : Dec 31, 2014
Study Type : Commentary
Additional Links
Diseases : Whooping Cough
Additional Keywords : Asymptomatic Transmission
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

Asymptomatic transmission of Bordatella pertussis may explain the recent resurgence of whooping cough and neither whole-cell or acellular vaccines prevent infection and transmission.Dec 01, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Microbiol Infect. 2016 Dec 1 ;22 Suppl 5:S96-S102. Epub 2016 Oct 27. PMID: 28341014
Article Published Date : Dec 01, 2016
Study Type : Review
Additional Links
Diseases : Whooping Cough
Additional Keywords : Vaccine Failure
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: DPT, Vaccination: Pertussis
[+]

Both whole-cell and acellular pertussis vaccines are effective at reducing disease severity but not transmission, resulting in outbreaks in vaccinated cohorts.Oct 31, 2015

Pubmed Data : Pathog Dis. 2015 Nov ;73(8). Epub 2015 Aug 6. PMID: 26253079
Article Published Date : Oct 31, 2015
Study Type : Review
Additional Links
Diseases : Whooping Cough
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

Pertussis vaccination and asthma: is there a link?Aug 23, 1994

Pubmed Data : JAMA. 1994 Aug 24-31;272(8):592-3. PMID: 8057511
Article Published Date : Aug 23, 1994
Study Type : Commentary
Additional Links
Diseases : Asthma, Autoimmune Diseases, Whooping Cough
Additional Keywords : Diseases that are Linked
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

Resurgence of the whopping cough in the UK is likely attributed to vaccine failure.Dec 02, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vaccine. 2013 Dec 2 ;31(49):5903-8. Epub 2013 Oct 16. PMID: 24139837
Article Published Date : Dec 02, 2013
Study Type : Viral
Additional Links
Diseases : Whooping Cough
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis
[+]

Substantial evidence supports the idea that pertussis toxin is a major contributor to pertussis pathology, including the severe respiratory symptoms associated with this disease.Oct 31, 2015

Pubmed Data : Pathog Dis. 2015 Nov ;73(8). Epub 2015 Sep 21. PMID: 26394801
Article Published Date : Oct 31, 2015
Study Type : Review
Additional Links
Diseases : Pertussis, Whooping Cough
[+]

The study results can be interpreted as a partial genetic escape of pathogenic strains of B. pertussis beyond the reach of the pertussis vaccines.Dec 31, 2014

Pubmed Data : Epidemiol Mikrobiol Imunol. 2015 ;64(3):130-8. PMID: 26448300
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: Pertussis
[+]

These results suggest that the immune pressure of vaccination is one major driving force for the evolution of B. pertussis.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:12888. Epub 2015 Aug 18. PMID: 26283022
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Pertussis, Whooping Cough
Anti Therapeutic Actions : Vaccination: Pertussis

Copyright: drmicrobe / 123RF Stock Photo

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Dr. Offit presents a flawed argument that "misguided" parents are to blame for the "reemergence" of infectious diseases. A deeper investigation into the statistics he quotes brings about a more accurate argument.
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