Pharmacological Actions (501)

What is Cumulative Knowledge?

Cumulative Knowledge is determined by ascribing a numerical value to the various study types weighted in descending order as follows: (1) Meta-Analysis; (2) Human Study; (3) Human: Case Study; (4) Animal: Transgenic; (5) Animal; (6) In Vitro; (7) Review; and (8) Commentary.

Pharmacological Action Name	Cumulative Knowledge	Abstracts
Anti-Inflammatory Agents	39739	15859
Antioxidants	34553	14500
Neuroprotective Agents	20061	7949
Tumor Necrosis Factor (TNF) Alpha Inhibitor	11697	4806
Antiproliferative	10001	7491
Analgesics	9680	1472
Apoptotic	9585	7379
Cardioprotective	9504	2963
Interleukin-6 Downregulation	9337	3613
Hypoglycemic Agents	9221	2076
Hypolipidemic	9173	2038
Hepatoprotective	8989	3831
Antidepressive Agents	7918	1467
Gastrointestinal Agents	7667	2275
Antihypertensive Agents	7081	1029
Chemopreventive	6580	2166
Immunomodulatory	6531	2360
Interleukin-1 beta downregulation	6063	2940
NF-kappaB Inhibitor	5952	3464
Anti-Apoptotic	5571	3161
Anti-Anxiety Agents	4856	805
Renoprotective	4544	1971
Chemotherapeutic	4390	1635
Chemoprotective Agents	4278	1621
Anti-Bacterial Agents	4228	1989
Anticholesteremic Agents	4093	669
Nrf2 activation	3156	1794
Antiviral Agents	3095	1702
Malondialdehyde Down-regulation	3028	992
Anti-metastatic	2870	2182
Radioprotective	2398	713
Superoxide Dismutase Up-regulation	2385	929
Cyclooxygenase 2 Inhibitors	2264	1327
Antineoplastic Agents	2235	1468
Anti-Fibrotic	2209	1052
Anticarcinogenic Agents	2152	1018
Cell cycle arrest	2120	1715
Osteoprotective	2039	686
Insulin Sensitizers	1957	422
Prophylactic Agents	1700	335
Gastroprotective	1695	702
Chemosensitizer	1657	1270
Antimicrobial	1577	790
MicroRNA modulator	1560	897
Heme oxygenase-1 up-regulation	1336	776
Interleukin-10 upregulation	1296	436
Anti-Ulcer Agents	1250	341
Anticonvulsants	1163	299
Matrix metalloproteinase-9 (MMP-9) inhibitor	1141	720
Interleukin-8 downregulation	1107	402
Antinoceceptive	959	291
Matrix metalloproteinase-2 (MMP-2) inhibitor	944	588
Vasodilator Agents	892	233
Detoxifier	856	254
Enzyme Inhibitors	846	399
Autophagy Up-regulation	838	559
Cytoprotective	809	401
Photoprotective	778	304
Immunostimulatory	772	235
Tumor Suppressor Protein p53 Upregulation	755	554
Brain-derived neurotrophic factor modulator	745	280
Antifungal Agents	730	422
Angiogenesis Inhibitors	724	481
Bcl-2 protein down-regulation	711	529
Nitric Oxide Inhibitor	705	356
Vascular Endothelial Growth Factor Inhibitors	611	335
Anti-Allergic Agents	598	221
Transforming growth factor beta (TGF-β) inhibitor	580	292
Interferon Gamma Reducer	569	215
Pancreato Protective Agents	554	299
Antidiarrheals	539	116
Genoprotective	522	203
Anti-Asthmatic Agents	510	148
Interleukin-17 downregulation	502	192
Regenerative	486	201
Anti-atherogenic	482	162
Anxiolytic	481	69
Hypotensive	467	63
Interleukin-4 downregulation	460	173
Fertility Agents: Male	455	123
Vasoprotective	451	108
Anti-Angiogenic	421	284
Alpha-glucosidase inhibitor	411	301
Catalase Up-Regulation	403	165
Postaglandin PGE2 downregulation	386	199
SIRT1 Activator	382	190
Radiosensitizer	372	247
Interleukin-18 down-regulation	372	183
Interleukin-10 downregulation	367	136
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	363	237
Glutathione Upregulation	359	110
Anti-Glycation Agents	351	167
Dermatologic Agents	339	40
Wnt/β-catenin signaling pathway modulation	330	224
Uricosuric Agents	328	83
Neurogenesis	325	173
Nitric Oxide Enhancer	324	90
STAT3 Inhibitor	322	216
Antiparasitic Agents	320	185
Autophagy Inhibitors	302	188
Wnt/β-catenin signaling pathway modulation	300	224
Angiogenesis Inducing Agents	290	149
Telomere Protective	281	39
Cytotoxic	276	234
Alpha-amylase inhibitor	268	178
Acetylcholinesterase Inhibitor	259	128
Fertility Agents: Female	251	52
Laxative	241	38
Matrix metalloproteinase-3 (MMP-3) inhibitor	238	107
Vascular Endothelial Growth Factor A Inhibitor	231	127
Adiponectin upregulation	229	41
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	229	104
Immunomodulatory: Th17 downregulation	227	100
Chondroprotective	226	116
Neuritogenic	224	108
Antimutagenic Agents	218	138
Cardiovascular Agents	215	35
Platelet Aggregation Inhibitors	214	50
P21 Activation	206	144
Interleukin-12 downregulation	203	77
Prostaglandin PGE2 downregulation	194	89
Anti-Adipogenic	193	108
Interleukin-4 upregulation	182	70
Secretagogue	178	38
Interleukin-2 Downregulation	177	73
Appetite Suppresant	177	27
Osteogenic	175	71
Insulin-releasing	169	70
Anti-Tumor	167	78
Leishmanicidal	164	110
Proliferative	162	98
Interleukin-1 alpha downregulation	162	67
Antioxidant Effects	159	45
Neuroplasticity enhancement	158	54
Transforming growth factor beta (TGF-β) upregulation	158	66
Heat Shock Protein Inducer	156	57
Anti-HIV Agents	155	96
Matrix metalloproteinase-1 (MMP-1) inhibitor	155	92
Interleukin-5 downregulation	154	65
interleukin-13 down-regulation	150	75
Telomerase Upregulation	149	37
Anti-Platelet	144	50
Cyclin D1 Down-Regulation	143	106
Antispasmodic	141	38
Caspase-3 Activation	137	90
Hypnotics and Sedatives	137	54
Glucagon Like peptide 1 (GLP-1) Up-regulation	131	36
Anti-Cachexic Agents	129	50
Angiotensin-Converting Enzyme Inhibitors	129	63
Vascular Cell Adhesion Molecule-1 Inhibitor	126	37
Antimalarials	125	78
Anti-Androgen	117	27
Histone deacetylase inhibitor	113	81
DNA Repair Up-regulation	110	34
Interleukin-23 Downregulation	107	42
Cardiotonic Agents	106	10
Immunosuppressive Agents	103	52
Vascular Endothelial Growth Factor Regulator	103	50
Phase II Detoxification Enzyme Inducer	100	55
Telomerase Inhibitor	98	65
Calcium Channel Blockers	98	29
Wnt/β-catenin pathway down-regulation	96	58
Epidermal growth factor receptor (EGFR) inhibitor	96	67
Anti-Infective Agents	92	47
Antitussive Agents	92	21
Xanthine oxidase inhibitor	91	49
Quorum Sensing Inhibition	90	85
Bronchodilator Agents	90	17
Hypoxia-inducible factor-1 (HIF-1) inhibitor	89	33
Insulin-Like Growth Factor Inhibition/Downregulation	88	19
Galactogogue	87	11
Cyclooxygenase Inhibitors	86	45
Cyclooxygenase 1 Inhibitor	85	62
Appetite Depressants	84	14
Anti-thrombotic	79	34
Anti-pyretic	76	33
Estrogen Receptor Modulators	75	40
Tumor Necrosis Factor (TNF) Alpha Enhancer	73	26
NF-E2-Related Factor-2 (Nrf2) Modulator	72	41
Neurorestorative	71	21
Caspase-9 Activation	71	47
Adiponectin Down-Regulation	68	11
Aphrodisiac	68	23
Anti-Proliferative	68	56
Multidrug Resistance Gene Modulators	67	57
Malonaldehyde (MDA) Down-Regulation	65	17
Heme oxygenase-1 inducer	63	43
Ergogenic	63	8
Interferon-gamma (IFN-gamma) inducer	63	20
Antiemetics	62	6
Antiprotozoal Agents	61	32
Iron Chelating Agents	61	22
Proteasome Inhibitors	60	41
Bax/Bcl2 ratio: Increase	58	44
Thermogenic	57	9
Diuretics	57	15
Serotonergic	56	12
GABA Modulators	55	23
Enzyme Inhibitors: Pancreatic Lipase	54	25
Cholagogues and Choleretics	54	12
Aromatase Inhibitors	53	36
Photosensitizing Agents	52	24
Interleukin-2 upregulation	51	13
Lipolytic	51	19
5-alpha reductase inhibitor	51	18
Anti-Retroviral Agents	51	20
Survivin Down-Regulation	50	44
Lipoxygenase Inhibitors	50	27
Interleukin-12 upregulation	49	14
Reverse Transcriptase Inhibitors	49	31
Heat Shock Protein Down-Regulation	49	28
5-Lipoxygenase Inhibitor	48	31
Chelating Agents	48	25
Insecticidal	46	24
5-Lipoxygenase Inhibitor	46	31
Histamine Antagonists	45	17
Histamine Antagonists	45	17
Anabolic Agents	45	12
Fibroblast growth factor 21 upregulation	44	18
Acid Blockers	42	17
Carcinogens	42	6
Bcl-xL down-regulation	41	30
Interferon Inducers	41	10
Enzyme Activators	40	25
Interleukin-22 Downregulation	40	20
Drug synergy	40	11
Antiurolithiatic	40	13
Appetite Stimulants	39	8
Leukotriene Antagonists	38	9
Cholinesterase Inhibitors	38	28
Insulin Down-Regulation	38	7
Proton Pump Inhibitor	38	14
Glucagon Like Peptide 1 (GLP-1) Down-Regulation	37	7
Neuromodulatory	37	7
Ghrelin Down-Regulation	36	6
Interleukin-8 upregulation	35	5
Analgesics: Non-Narcotic	35	10
Antimycobacterial	35	19
Antipsychotic Agents	34	15
Spermatogenic	34	12
Uterotonic	34	11
Cholecystokinin (CCK) Up-regulation	34	6
Bax/Bcl2 Ratio: Decrease	33	21
HIV Protease Inhibitors	33	21
Interleukin-6 upregulation	33	12
Protein Kinase Inhibitors	32	21
Dopaminergic	32	10
Matrix Metalloproteinase-7 (MMP-7) Inhibitor	32	21
Caspase-8 activation	32	22
Aldose reductase inhibitor	32	9
Nootropic Agents	30	18
Matrix metalloproteinase-8 (MMP-8) inhibitor	30	12
STAT3 Activation	29	20
Fibrinolytic Agents	28	7
Androgen Antagonists	27	6
Prostaglandin Antagonists	27	13
Vascular Endothelial Growth Factor C Inhibitor	27	10
Glucose Uptake Optimization	26	9
Interleukin-17 upregulation	26	5
Fertility Agents	25	10
Detoxifier: Radionuclide Removal	25	5
Neurominidase Inhibitor	25	24
Remyelination	24	13
Leptin Down-Regulation	23	8
Monocyte chemotattractant protein-1 (MCP-1) Inhibitor	23	4
Anti-cancer	23	6
Natriuretic Agents	23	4
Viral Hemagglutinin Inhibitor	22	16
Endothelin-1 Inhibitor	22	3
Topoisomerase II Inhibitor	22	20
Anticoagulants	22	18
Gluconeogenesis Inhibitor	21	15
Matrix Metalloproteinase-12 (MMP-12) Inhibitor	21	11
Fatty Acid Oxidation	20	2
Adenosine deaminase inhibitor	20	7
Cholecystokinin Releaser	20	2
Hematopoietic	20	9
Interleukin-18 upregulation	20	11
Protease Inhibitors	19	10
Insect Repellents	19	12
Adenosine Monophosphate (AMP)-activated Protein Kinase (AMPK	18	4
Tyrosinase inhibitors	18	17
P38 Mitogen-Activated Protein Kinase Modulator	18	12
Gene Protective	18	6
Oncogene Suppressor	18	14
Immune Enhancing Properties	18	5
Topoisomerase I inhibitor	17	15
Anticholinergic	17	5
Monoamine Oxidase Inhibitors	16	5
Peptide YY (PYY) Up-Regulation	16	4
Interleukin-21 downregulation	16	4
Glucose transporter-1 (GLUT1) expression down-regulation	16	8
Antilipemic Agents	15	2
Hepatocyte growth factor (HGF) inhibitor	15	4
Interleukin-1 beta upregulation	15	5
Antithrombotic	15	5
Antitubercular Agents	15	5
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	15	10
Paraptosis	14	14
Contraceptive Agents: Male	14	3
Cell Differentiation Inducer	14	11
Glutathione S-transferase Inhibitor	14	4
Teratogens	14	3
Neocardiogenic	14	11
Neocardiogenic	14	11
Vascular Endothelial Growth Factor A Enhancer	13	7
Muscle Relaxants: Central	13	4
Leukotriene B4 downregulation	13	4
Glutathione Peroxidase 1 (GPx1) Up-Regulation	13	7
Phase I Detoxification Enzyme Inducer	13	7
Anti-collagenase	13	3
Vasopressin Inhibitor	12	2
Carminative	12	2
Immunomodulatory: T-Cell down-regulation	12	2
Dopamine Agents	12	2
Endocannabinoid down-regulation	12	2
VEGFR3 inhibition	12	3
Interleukin-13 Up-Regulation	12	3
Metallothionein Up-regulation	12	2
Insulin Receptor Modulator	12	2
Mucolytic	12	2
Disinfectants	12	3
Immunomodulatory: Innate Immunity Up-Regulation	12	2
Mitogen-activated protein kinase inhibitors	12	3
Anti-edemic	12	2
Adrenergic alpha-Antagonists	11	2
P16 Activation	11	2
Tocolytic Agents	11	2
Insulinotrophic	11	7
15-Lipoxygenase (15-LOX) Inhibitor	11	8
Interleukin-1 receptor antagonist	11	2
Histamine down-regulation	11	9
PI3K/Akt/signaling suppression	11	6
Matrix Metalloproteinase-8 Inhibitor	11	2
Mitogen-activated protein kinase kinase 4 (MEK4)	11	2
Respiratory System Agents	10	1
Androgens	10	1
Peptide YY (PYY) Down-regulation	10	1
Matrix Metalloproteinases Inhibitors	10	6
Neurotransmitter Uptake Inhibitors	10	1
Estrogens	10	1
Phosphorylase Kinase Inhibitors	10	1
Glutathione peroxidase 1 (GPx1) inhibitors	10	1
cAMP up-regulation	10	1
Immunomodulatory: CD23+ Mature Macrophage Down-Regulation	10	1
Insulin Antagonists	10	1
Hormones	10	1
PER2 Protein Expression Up-regulation	10	1
Gastric Inhibitory Polypeptide Up-Regulation	10	1
CYP3A enzyme induction	10	1
Immunostimulatory: IgA Production Up-Regulation	10	1
Isoprostane Down-Regulation	10	1
Central Nervous System Depressants	10	1
Diacylglyceride acyltransferase 1 (DGAT1) Inhibition	10	1
Immunomodulatory: Immunoglobulin G up-regulation	10	1
NOX2 inhibitor	10	1
Immunomodulatory: Immunoglobulin M Up-Regulation	10	1
Mitochondrial Superoxide Dismutase Upregulation	10	6
Interleukin-3 upregulation	10	1
Drug sparing	10	1
Glucose transporter-2 (GLUT2) expression down-regulation	10	6
Intracellular adhesion molecule down-regulation	10	1
Oxytocin inducer	10	1
Glucose transporter-2 (GLUT2) expression up-regulation	10	1
Interleukin 1 receptor antagonist (IL-1Ra) up-regulation	10	1
Insulin-mimetic	9	6
Selective estrogen enzyme modulator (SEEM)	9	7
Excitatory Amino Acid Agonists	9	5
Prostaglandin E Synthase-1 (PGES-1) Down-Regulation	9	3
Redox Modulator	9	5
Cannabinoid Receptor Antagonist/Inverse Agonist	9	7
Caspase-7 Activation	9	7
Analgesics: Opioid	9	6
Selective Estrogen Receptor Modulators	8	5
Monoaminergic	8	4
Vascular Endothelial Growth Factor D Inhibitor	8	4
Enzyme Inhibitors: Pancreatic Amylase	8	6
Benzodiazepine receptor agonist	8	6
NADPH Oxidase Inhibitors	8	4
Angiogenesis Modulating Agents	8	5
Thrombolytic	8	5
ER beta receptor up-regulation	7	5
Tyrosinase Inhibition	7	5
Acetylcholinesterase Down-Regulation	7	4
Chemotherapeuticm	7	5
HER-2 oncoprotein down-regulation	7	2
Insulin-Like Growth Factor Enhancer/Upregulation	7	4
Antigiardial agents	7	4
Intracellular adhesion molecule-1 (ICAM-1)	7	5
E-cadherin down-regulation	6	5
Anti-Arrhythmia Agents	6	4
Anti-Estrogenic	6	4
Trypanocidal Agents	6	5
AMP-activated protein kinase modulation	6	4
Trypsin Inhibitors	6	4
Caspase-3 Inhibition	6	4
AKT-mammalian target of rapamycin (mTOR) pathway inhibitor	6	5
TRAIL sensitizer	6	5
Chemokine (C-C motif) Ligand 2 (CCL2) Down-Regulation	6	4
PI3K-AKT inhibitor	6	4
Bone Density Conservation Agents	6	3
Cholinergic Agents	5	3
Antacids	5	3
Thromboxane (TXB) Inhibitors	5	4
HIV Fusion Inhibitors	5	4
Cryoprotective Agents	5	4
HMG-CoA reductase inhibitor	5	4
Interleukin-15 downregulation	5	3
Protein tyrosine phosphatase 1B (PTP1B) modulator	5	3
Extracellular Signal-Regulated Kinases Modulator	5	4
Lactate Dehydrogenase A Inhibitor	5	3
Vascular smooth muscle cell (VSMC) inhibitor	5	5
Spermicidal Activity	5	1
Angiotensin II Type 1 Receptor Blockers	5	3
Inhibitor of Nuclear Factor Kappa-B Kinase (IKK)	5	4
SGLT1 inducer	4	2
Dental Disinfectants	4	1
Tumor Suppressor Protein p73 Upregulation	4	3
Anti-Inflammatory Agents: Non-Steroidal	4	2
Radiation-Protective Agents	4	2
Histamine Agents	4	3
Antipruritics	4	2
SGLT1 inducer	4	2
Ghrelin Up-regulation	4	2
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Upregulation	4	2
Metal Chelation: Copper	4	3
Vitamin D Receptor (VDR) Modulator	4	3
Erythropoietic	4	3
Peroxisome Proliferators	4	2
Schistosomicides	4	2
Scolicidal	4	4
Antiparkinson Agents	4	2
Cyclin-dependent kinase inhibitor: P16INK4	4	3
Beta-Endorphin Enhancer	4	2
C-Jun N-Terminal Kinases (JNK) Modulator	4	3
Tumor Necrosis Factor (TNF) Alpha Upregulation	4	2
Adrenergic alpha-Agonists	4	3
Paraoxonase down-regulation	4	2
Immunomodulatory: Regulatory T Cell Up-Regulation	4	2
Estrogen Receptor Agonist	3	3
P-glycoprotein Inhibitors	3	3
Survival protein down-regulation	3	2
Matrix metalloproteinase-14 (MMP-14) inhibitor	3	3
Adrenergic beta-Agonists	3	2
Cholinergic Antagonists	3	2
Platelet aggregation inhibitor: collagen-induced aggregation	3	2
Insecticides	3	2
Interleukin-1 alpha upregulation	3	2
12-lipoxygenase (12-LOX) Inhibitor	3	2
HIV-1 Integrase Inhibitor	3	3
p300/NF-κB down-regulation	3	3
Steroidogenesis	3	2
Intercellular adhesion molecule 3 down-regulation	3	2
Expectorants	3	2
Cyclin-Dependent Kinase Inhibitor	3	3
Antimitotic Agents	3	3
Estradiol 3-glucuronide enhancer	3	3
Atrial Natriuretic Factor Modulation	3	2
Beta-Defensin-2 Up-Regulation	3	2
NF-kappa-B-inducing kinase (NIK) modulator	3	2
Estradiol Antagonists	3	2
Anti-Infective Agents: Urinary	3	2
Vanilloid Receptor-1 Modulator	3	3
Histamine up-regulation	3	2
Fatty Acid Synthesis Inhibitors	3	3
Forkhead Transcription Factor Family O (FOXO) Modulator	3	2
Contraceptive Agents	3	2
Quinone Reductase-Inducer	3	2
High-mobility group box-1 (HMGB1) inhibitor	2	1
Reactive Oxygen Species (ROS) attenuation	2	2
Phosphodiesterase Inhibitors	2	2
Anti-elastase	2	2
Calcium Desensitizer	2	1
Lymphagogue	2	1
Immunologic Factors	2	1
Muscarinic Antagonists	2	2
1-Glutamine Uptake Inhibitor	2	2
Receptor activator of NF-κB (RANK) gene expression	2	2
Adenosine Monophosphate (AMP)-Activated Protein Kinase (AMPK) Down-Regulation	2	1
Antinitrosation	2	1
Alpha-hemolysin inhibitor	2	2
Arginine Vasopressin (AVP) up-regulation.	2	1
Anthelmintics	2	1
Thromboxane B2 Inhibitor	2	2
Interleukin-5 upregulation	2	1
Histamine Agonists	2	1
Receptor-Related Orphan Receptor (ROR)-Alpha1 Inhibitor	2	1
Enzyme Inhibitors: Maltase Inhibition	2	1
β(2)-adrenoceptor up-regulation	2	1
Antilipolytic	2	2
Sigma-1 Receptor Agonist	2	2
Stearoyl coenzyme A desaturase-1 modulator	2	1
Anesthetics	2	1
CYP1A1 Transcription Inhibitor	2	1
BRCA-1 Downregulation	2	2
Myorelaxant	2	1
Neutrophil Activation: Down-Regulation	2	1
Antidiuretic Agents	2	1
Redox Balancer	2	1
Abortifacient Agents	2	1
β-secretase Inhibitor	2	2
Akt-dependent HO-1 expression up-regulation	2	1
Central Nervous System Agents	2	1
Arylesterase down-regulation	2	1
Breast cancer resistance protein (BCRP) down-regulation	2	2
GSH-Px Up-Regulation	2	1
Uncoupling Agents	2	1
Immunomodulatory: CD8+ Up-regulation	2	1
Myosin heavy chain alpha (MHCalpha) reducer	2	1
Neutrophil Rolling Inhibitor	2	1
Noradrenergic	2	1
Human androgen receptor (AR) antagonist	2	2
Leukotriene C4 Downregulation	2	2
Sarcoplasmic Calcium ATPase Up-regulation	2	1
Adjuvants: Immunologic	2	1
Ovogenic	2	1
Spasmogenic	2	1
Stomachic	2	1
PPAR-Gamma Up-Regulation	2	2
Bronchoconstrictor Agents	2	1
JAM3 gene down-regulation	2	1
Antifibrinolytic Agents	2	2
Adrenergic Agents	2	1
Serotonin Agents	2	1
Follicle-stimulating hormone receptor (FSHR) up-regulation	2	1
Cicatrizing	2	1
Cyclin-Dependent Kinase Inhibitor: P16	2	2
Carbonic Anhydrase Inhibitors	2	1
Incretin Modulator	2	1
Hydroperoxidase Inhibitor	2	1
Histamine H2 Antagonists	2	2
Adrenergic Agonists	2	2
Serotonin Agonists	2	1
Food Preservatives	2	2
Phase I Detoxification Enzyme Inhibitor	2	1
Coccidiostats	2	1
Progestagenic	2	1
Glycine Agents	2	1
Lipotropic Agents	2	1
RANTES (CCL5) Inhibitor	2	2
Environmental Pollutants	2	1
ER alpha receptor up-regulation	2	1
Serum ceruloplasmin oxidase reducer	2	1
Progesterone receptor (PR) up-regulation	2	1
Death receptor up-regulation	2	1
Prostaglandin PGF2 downregulation	2	2
Muscarinic Agonists	2	1
Opioid Endogenous Up-regulation	2	1
5-Hydroxyeicosatetraenoic acid (5-HETE) Inhibitor	1	1
Secretagogues: Prolactin Up-Regulation	1	1
Free Radical Scavengers	1	1
Arginase 1 (Arg1) up-regulation	1	1
PKM2 downregulation	1	1
Glucose transporter-5 (GLUT5) expression down-regulation	1	1
Brain-Associated Sulfotransferase Down-Regulation	1	1
Transient Receptor Potential Melastatin 2 Inhibition	1	1
Glyoxalase 1 inhibitor	1	1
Molecular Probes	1	1
Neovasculogenesis	1	1
Ionophores	1	1
Emmenagogue	1	1
Antidepressive Agents: Second-Generation	1	1
Zinc-dependent metalloproteinase inhibitor	1	1
Caspase-14 Upregulation	1	1
STAT3-NFκB Signaling: downregulation	1	1
Phospholipase D Inhibitors	1	1
Transient receptor potential vanilloid type-2 activation	1	1
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Inhibitor	1	1
Calcium/calmodulin dependent protein kinase II inhibitor	1	1
Matrix metalloproteinase-16 (MMP-16) inhibitor	1	1
Nonpeptidyl Inhibitors	1	1
IRAK-MAPK Modulator	1	1
Antibiotics: Antifungal	1	1
Radiation-Sensitizing Agents	1	1
1-Leucine Uptake Inhibitor	1	1
Ribonucleotide Reductase Inhibitor	1	1
Erk/MAP Inactivation	1	1
Caspase-2 Activation	1	1
Air Pollutants: Radioactive	1	1
Aminopeptidase N (APN/CD13) inhibitor	1	1
Chemosterilants	1	1
Apaf-1/caspase-dependent apoptotic pathway activator	1	1
Protein Kinase C Inhibitor	1	1
Hemolytic Agents	1	1
Dopamine Agonists	1	1
Matrix metalloproteinase-17 (MMP-17) inhibitor	1	1
Hypomethylating	1	1
Radiopharmaceuticals	1	1
Endocannabinoid Modulator	1	1
S-phase kinase associated protein 2 inhibition	1	1
Eryptotic	1	1
Serine Proteinase Inhibitors	1	1
Phosphorylated Rb Down-Regulation	1	1
Cyclin-Dependent Kinase 4 Down-Regulation	1	1
Cancerous inhibitor of protein phosphatase 2A inhibitor	1	1
Dopamine Antagonists	1	1
Maspin (Protease Inhibitor) Up-Regulation	1	1
Neuroimmunomodulation	1	1
Chymotrypsin Inhibitor	1	1
Astringents	1	1
Prostaglandin H Synthase-1 (PGHS-1) Inhibits	1	1
Anti-Psychotic	1	1
Dopamine Receptor D3 Antagonist	1	1
Mast Cell Activation Inhibitor	1	1
mTOR/S6K pathway Activator	1	1
Human Polymorphonuclear Leukocyte Degranulation Inhibitor	1	1
Leukotriene D4 antagonist	1	1
17beta-hydroxysteroid dehydrogenase inhibitor	1	1
Enkephalinase inhibitor	1	1
EpCAM surface marker down-regulation	1	1
Akt-SREBP-1 activater	1	1
Oxidants	1	1
Palmitoylation Inhibitors	1	1
Sulfonation	1	1
PRL-3 Down-Regulation	1	1
Prostaglandin H Synthase-2 (PGHS-2) Up-Regulation	1	1
Dipeptidyl-Peptidase IV Inhibitors	1	1
RANK Downregulation	1	1
Enoyl-acyl Carrier Protein (ACP) Reductase Inhibitors	1	1
Oxytocics	1	1
Cytotoxins	1	1
Hematologic Agents	1	1
Carbonyl Reductase 1Inhibitor	1	1
Psychedelic	1	1
IGF-1R expression down-regulation	1	1
Hydroxyheptadecatrienoate (HHT) Inhibitor	1	1
5-HTergic	1	1
Estrogen Antagonists	1	1
Superoxide Scavenger	1	1
Herbicides	1	1
Hepatoma-derived growth factor (HDGF) inhibitor	0	1

Natural Health Research Discovery

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Pharmacological Actions (501)