| Hepatoma-derived growth factor (HDGF) inhibitor | 0 | 1 | |
| Brain-Associated Sulfotransferase Down-Regulation | 1 | 1 | |
| Sulfonation | 1 | 1 | |
| 5-Hydroxyeicosatetraenoic acid (5-HETE) Inhibitor | 1 | 1 | |
| Prostaglandin H Synthase-2 (PGHS-2) Up-Regulation | 1 | 1 | |
| Matrix Metalloproteinase-8 Inhibitor | 1 | 1 | |
| Arginase 1 (Arg1) up-regulation | 1 | 1 | |
| Hemolytic Agents | 1 | 1 | |
| Dopamine Agonists | 1 | 1 | |
| Erk/MAP Inactivation | 1 | 1 | |
| Caspase-14 Upregulation | 1 | 1 | |
| Neovasculogenesis | 1 | 1 | |
| Oxidants | 1 | 1 | |
| Calcium/calmodulin dependent protein kinase II inhibitor | 1 | 1 | |
| Palmitoylation Inhibitors | 1 | 1 | |
| Ionophores | 1 | 1 | |
| Antidepressive Agents: Second-Generation | 1 | 1 | |
| PRL-3 Down-Regulation | 1 | 1 | |
| Psychedelic | 1 | 1 | |
| RANK Downregulation | 1 | 1 | |
| Molecular Probes | 1 | 1 | |
| Cyclin-Dependent Kinase 4 Down-Regulation | 1 | 1 | |
| Dopamine Antagonists | 1 | 1 | |
| Endocannabinoid Modulator | 1 | 1 | |
| Eryptotic | 1 | 1 | |
| Caspase-2 Activation | 1 | 1 | |
| Oxytocics | 1 | 1 | |
| Nonpeptidyl Inhibitors | 1 | 1 | |
| Antibiotics: Antifungal | 1 | 1 | |
| Superoxide Scavenger | 1 | 1 | |
| 1-Leucine Uptake Inhibitor | 1 | 1 | |
| IRAK-MAPK Modulator | 1 | 1 | |
| Air Pollutants: Radioactive | 1 | 1 | |
| Matrix metalloproteinase-16 (MMP-16) inhibitor | 1 | 1 | |
| Aminopeptidase N (APN/CD13) inhibitor | 1 | 1 | |
| Apaf-1/caspase-dependent apoptotic pathway activator | 1 | 1 | |
| Muscle Relaxants: Central | 1 | 4 | |
| Chymotrypsin Inhibitor | 1 | 1 | |
| Dopamine Receptor D3 Antagonist | 1 | 1 | |
| Secretagogues: Prolactin Up-Regulation | 1 | 1 | |
| Cancerous inhibitor of protein phosphatase 2A inhibitor | 1 | 1 | |
| 12-lipoxygenase (12-LOX) Inhibitor | 1 | 1 | |
| Transient Receptor Potential Melastatin 2 Inhibition | 1 | 1 | |
| Hypomethylating | 1 | 1 | |
| Matrix metalloproteinase-17 (MMP-17) inhibitor | 1 | 1 | |
| Dipeptidyl-Peptidase IV Inhibitors | 1 | 1 | |
| Enkephalinase inhibitor | 1 | 1 | |
| EpCAM surface marker down-regulation | 1 | 1 | |
| Interleukin-1 beta upregulation | 1 | 5 | |
| Neuroimmunomodulation | 1 | 1 |  |
| Anti-Psychotic | 1 | 1 | |
| STAT3-NFκB Signaling: downregulation | 1 | 1 | |
| Phosphodiesterase Inhibitors | 1 | 2 | |
| PKM2 downregulation | 1 | 1 | |
| Transient receptor potential vanilloid type-2 activation | 1 | 1 | |
| Maspin (Protease Inhibitor) Up-Regulation | 1 | 1 | |
| Astringents | 1 | 1 | |
| Zinc-dependent metalloproteinase inhibitor | 1 | 1 | |
| Cytotoxins | 1 | 1 | |
| Hematologic Agents | 1 | 1 | |
| Disinfectants | 1 | 3 | |
| Enoyl-acyl Carrier Protein (ACP) Reductase Inhibitors | 1 | 1 | |
| 17beta-hydroxysteroid dehydrogenase inhibitor | 1 | 1 | |
| Phospholipase D Inhibitors | 1 | 1 | |
| Antifibrinolytic Agents | 1 | 2 | |
| Human Polymorphonuclear Leukocyte Degranulation Inhibitor | 1 | 1 | |
| Leukotriene D4 antagonist | 1 | 1 | |
| Mast Cell Activation Inhibitor | 1 | 1 | |
| Akt-SREBP-1 activater | 1 | 1 | |
| Protein Kinase C Inhibitor | 1 | 1 | |
| Radiation-Sensitizing Agents | 1 | 1 | |
| mTOR/S6K pathway Activator | 1 | 1 | |
| Ribonucleotide Reductase Inhibitor | 1 | 1 | |
| Fatty Acid Synthesis Inhibitors | 1 | 3 | |
| Contraceptive Agents | 1 | 2 | |
| Herbicides | 1 | 1 | |
| Estrogen Antagonists | 1 | 1 | |
| Serine Proteinase Inhibitors | 1 | 1 | |
| Carbonyl Reductase 1Inhibitor | 1 | 1 | |
| Radiopharmaceuticals | 1 | 1 | |
| S-phase kinase associated protein 2 inhibition | 1 | 1 | |
| Free Radical Scavengers | 1 | 1 | |
| Glucose transporter-5 (GLUT5) expression down-regulation | 1 | 1 | |
| Glyoxalase 1 inhibitor | 1 | 1 | |
| 5-HTergic | 1 | 1 | |
| Phosphorylated Rb Down-Regulation | 1 | 1 | |
| Hydroxyheptadecatrienoate (HHT) Inhibitor | 1 | 1 | |
| IGF-1R expression down-regulation | 1 | 1 | |
| Prostaglandin H Synthase-1 (PGHS-1) Inhibits | 1 | 1 | |
| Cryoprotective Agents | 1 | 4 | |
| Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Inhibitor | 1 | 1 | |
| Emmenagogue | 1 | 1 | |
| Anti-elastase | 2 | 2 | |
| Serotonin Agents | 2 | 1 | |
| Ovogenic | 2 | 1 | |
| Calcium Desensitizer | 2 | 1 | |
| Peroxisome Proliferators | 2 | 1 | |
| Opioid Endogenous Up-regulation | 2 | 1 | |
| PPAR-Gamma Up-Regulation | 2 | 2 | |
| Muscarinic Agonists | 2 | 1 | |
| CYP1A1 Transcription Inhibitor | 2 | 1 | |
| Histamine Agonists | 2 | 1 | |
| Enzyme Inhibitors: Maltase Inhibition | 2 | 1 | |
| Serotonin Agonists | 2 | 1 | |
| 1-Glutamine Uptake Inhibitor | 2 | 2 | |
| Adenosine Monophosphate (AMP)-Activated Protein Kinase (AMPK) Down-Regulation | 2 | 1 | |
| Lymphagogue | 2 | 1 | |
| Antinitrosation | 2 | 1 | |
| Tumor Necrosis Factor (TNF) Alpha Upregulation | 2 | 2 | |
| Immunologic Factors | 2 | 1 | |
| Alpha-hemolysin inhibitor | 2 | 2 | |
| Arginine Vasopressin (AVP) up-regulation. | 2 | 1 | |
| Anthelmintics | 2 | 1 | |
| Muscarinic Antagonists | 2 | 2 | |
| GSH-Px Up-Regulation | 2 | 1 | |
| BRCA-1 Downregulation | 2 | 2 | |
| Serum ceruloplasmin oxidase reducer | 2 | 1 | |
| Interleukin-5 upregulation | 2 | 1 | |
| Phase I Detoxification Enzyme Inhibitor | 2 | 1 | |
| Antilipolytic | 2 | 2 | |
| Progestagenic | 2 | 1 | |
| Prostaglandin PGF2 downregulation | 2 | 2 | |
| Insecticides | 2 | 2 | |
| Anesthetics | 2 | 1 | |
| RANTES (CCL5) Inhibitor | 2 | 2 | |
| Central Nervous System Agents | 2 | 1 | |
| Endothelin-1 Inhibitor | 2 | 3 | |
| Myorelaxant | 2 | 1 | |
| Breast cancer resistance protein (BCRP) down-regulation | 2 | 2 | |
| Neutrophil Activation: Down-Regulation | 2 | 1 | |
| Antidiuretic Agents | 2 | 1 | |
| Abortifacient Agents | 2 | 1 | |
| Progesterone receptor (PR) up-regulation | 2 | 1 | |
| Akt-dependent HO-1 expression up-regulation | 2 | 1 | |
| Reactive Oxygen Species (ROS) attenuation | 2 | 2 | |
| Arylesterase down-regulation | 2 | 1 | |
| Follicle-stimulating hormone receptor (FSHR) up-regulation | 2 | 1 | |
| Cicatrizing | 2 | 1 | |
| Cyclin-Dependent Kinase Inhibitor: P16 | 2 | 2 | |
| Myosin heavy chain alpha (MHCalpha) reducer | 2 | 1 | |
| Bronchoconstrictor Agents | 2 | 1 | |
| Neutrophil Rolling Inhibitor | 2 | 1 | |
| Noradrenergic | 2 | 1 | |
| Thromboxane B2 Inhibitor | 2 | 2 | |
| Human androgen receptor (AR) antagonist | 2 | 2 | |
| Leukotriene C4 Downregulation | 2 | 2 | |
| Adjuvants: Immunologic | 2 | 1 | |
| Immunomodulatory: CD8+ Up-regulation | 2 | 1 | |
| Receptor activator of NF-κB (RANK) gene expression | 2 | 2 | |
| Food Preservatives | 2 | 2 | |
| Gene Protective | 2 | 6 | |
| Coccidiostats | 2 | 1 | |
| Glycine Agents | 2 | 1 | |
| Histamine H2 Antagonists | 2 | 2 | |
| Sigma-1 Receptor Agonist | 2 | 2 | |
| Carbonic Anhydrase Inhibitors | 2 | 1 | |
| Stearoyl coenzyme A desaturase-1 modulator | 2 | 1 | |
| JAM3 gene down-regulation | 2 | 1 | |
| Adrenergic Agents | 2 | 1 | |
| Angiogenesis Modulating Agents | 2 | 5 | |
| Receptor-Related Orphan Receptor (ROR)-Alpha1 Inhibitor | 2 | 1 | |
| β(2)-adrenoceptor up-regulation | 2 | 1 | |
| Death receptor up-regulation | 2 | 1 | |
| Environmental Pollutants | 2 | 1 | |
| ER alpha receptor up-regulation | 2 | 1 | |
| Beta-Endorphin Enhancer | 2 | 1 | |
| Hydroperoxidase Inhibitor | 2 | 1 | |
| Adrenergic Agonists | 2 | 2 | |
| Antiparkinson Agents | 2 | 2 | |
| Uncoupling Agents | 2 | 1 | |
| Incretin Modulator | 2 | 1 | |
| Redox Balancer | 2 | 1 | |
| β-secretase Inhibitor | 2 | 2 | |
| Fertility Agents | 2 | 9 | |
| High-mobility group box-1 (HMGB1) inhibitor | 2 | 1 | |
| Spasmogenic | 2 | 1 | |
| Stomachic | 2 | 1 | |
| Lipotropic Agents | 2 | 1 | |
| Sarcoplasmic Calcium ATPase Up-regulation | 2 | 1 | |
| Histamine Agents | 2 | 3 | |
| Adrenergic beta-Agonists | 3 | 2 | |
| Matrix metalloproteinase-14 (MMP-14) inhibitor | 3 | 3 | |
| Vanilloid Receptor-1 Modulator | 3 | 3 | |
| HIV-1 Integrase Inhibitor | 3 | 3 | |
| Interleukin-1 alpha upregulation | 3 | 2 | |
| Quinone Reductase-Inducer | 3 | 2 | |
| Expectorants | 3 | 2 | |
| Cyclin-Dependent Kinase Inhibitor | 3 | 3 | |
| Survival protein down-regulation | 3 | 2 | |
| Estradiol 3-glucuronide enhancer | 3 | 3 | |
| Interleukin-15 downregulation | 3 | 2 | |
| P-glycoprotein Inhibitors | 3 | 3 | |
| Intercellular adhesion molecule 3 down-regulation | 3 | 2 | |
| Estradiol Antagonists | 3 | 2 | |
| Beta-Defensin-2 Up-Regulation | 3 | 2 | |
| Platelet aggregation inhibitor: collagen-induced aggregation | 3 | 2 | |
| Antimitotic Agents | 3 | 3 | |
| Atrial Natriuretic Factor Modulation | 3 | 2 | |
| Forkhead Transcription Factor Family O (FOXO) Modulator | 3 | 2 | |
| Histamine up-regulation | 3 | 2 | |
| Anti-Infective Agents: Urinary | 3 | 2 | |
| NF-kappa-B-inducing kinase (NIK) modulator | 3 | 2 | |
| Steroidogenesis | 3 | 2 | |
| Cholinergic Agents | 3 | 3 | |
| Estrogen Receptor Agonist | 3 | 3 | |
| p300/NF-κB down-regulation | 3 | 3 | |
| Cholinergic Antagonists | 3 | 2 | |
| Schistosomicides | 4 | 2 | |
| Anti-Inflammatory Agents: Non-Steroidal | 4 | 2 | |
| Intracellular adhesion molecule-1 (ICAM-1) | 4 | 5 | |
| Immunomodulatory: Regulatory T Cell Up-Regulation | 4 | 2 | |
| Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Upregulation | 4 | 2 | |
| Scolicidal | 4 | 4 | |
| Phase I Detoxification Enzyme Inducer | 4 | 6 | |
| Antipruritics | 4 | 2 | |
| Thrombolytic | 4 | 5 | |
| Monoamine Oxidase Inhibitors | 4 | 5 | |
| Chemotherapeuticm | 4 | 3 | |
| Erythropoietic | 4 | 3 | |
| SGLT1 inducer | 4 | 2 | |
| Paraoxonase down-regulation | 4 | 2 | |
| Tumor Suppressor Protein p73 Upregulation | 4 | 3 | |
| Vascular Endothelial Growth Factor A Enhancer | 4 | 7 | |
| Metal Chelation: Copper | 4 | 3 | |
| SGLT1 inducer | 4 | 2 | |
| Tyrosinase Inhibition | 4 | 4 | |
| Radiation-Protective Agents | 4 | 2 | |
| Cyclin-dependent kinase inhibitor: P16INK4 | 4 | 3 | |
| Anticholinergic | 4 | 5 | |
| C-Jun N-Terminal Kinases (JNK) Modulator | 4 | 3 | |
| Angiotensin II Type 1 Receptor Blockers | 4 | 3 | |
| Contraceptive Agents: Male | 4 | 3 | |
| Dental Disinfectants | 4 | 1 | |
| Adrenergic alpha-Agonists | 4 | 3 | |
| Vitamin D Receptor (VDR) Modulator | 4 | 3 | |
| Ghrelin Up-regulation | 4 | 2 | |
| Antacids | 5 | 3 | |
| Anti-Arrhythmia Agents | 5 | 4 | |
| Spermicidal Activity | 5 | 1 | |
| HMG-CoA reductase inhibitor | 5 | 4 | |
| Thromboxane (TXB) Inhibitors | 5 | 4 | |
| Extracellular Signal-Regulated Kinases Modulator | 5 | 4 | |
| Lactate Dehydrogenase A Inhibitor | 5 | 3 | |
| Protein tyrosine phosphatase 1B (PTP1B) modulator | 5 | 3 | |
| Inhibitor of Nuclear Factor Kappa-B Kinase (IKK) | 5 | 4 | |
| HIV Fusion Inhibitors | 5 | 4 | |
| Interleukin-18 upregulation | 6 | 9 | |
| TRAIL sensitizer | 6 | 5 | |
| Anti-Estrogenic | 6 | 4 | |
| PI3K-AKT inhibitor | 6 | 4 | |
| Interleukin-21 downregulation | 6 | 3 | |
| AMP-activated protein kinase modulation | 6 | 4 | |
| Monoaminergic | 6 | 4 | |
| Caspase-3 Inhibition | 6 | 4 | |
| AKT-mammalian target of rapamycin (mTOR) pathway inhibitor | 6 | 5 | |
| Trypanocidal Agents | 6 | 5 | |
| Chemokine (C-C motif) Ligand 2 (CCL2) Down-Regulation | 6 | 4 | |
| Trypsin Inhibitors | 6 | 4 | |
| E-cadherin down-regulation | 6 | 5 | |
| Bone Density Conservation Agents | 6 | 3 | |
| Vascular smooth muscle cell (VSMC) inhibitor | 7 | 5 | |
| Excitatory Amino Acid Agonists | 7 | 5 | |
| Acetylcholinesterase Down-Regulation | 7 | 4 | |
| HER-2 oncoprotein down-regulation | 7 | 2 | |
| ER beta receptor up-regulation | 7 | 5 | |
| Antigiardial agents | 7 | 4 | |
| Insulin-Like Growth Factor Enhancer/Upregulation | 7 | 4 | |
| Enzyme Inhibitors: Pancreatic Amylase | 8 | 6 | |
| Benzodiazepine receptor agonist | 8 | 6 | |
| NADPH Oxidase Inhibitors | 8 | 4 | |
| Selective Estrogen Receptor Modulators | 8 | 5 | |
| Vascular Endothelial Growth Factor D Inhibitor | 8 | 4 | |
| Insulin-mimetic | 9 | 6 | |
| Histamine down-regulation | 9 | 8 | |
| Selective estrogen enzyme modulator (SEEM) | 9 | 7 | |
| Cannabinoid Receptor Antagonist/Inverse Agonist | 9 | 7 | |
| Caspase-7 Activation | 9 | 7 | |
| Prostaglandin E Synthase-1 (PGES-1) Down-Regulation | 9 | 3 | |
| Analgesics: Opioid | 9 | 6 | |
| Redox Modulator | 9 | 5 | |
| Interleukin 1 receptor antagonist (IL-1Ra) up-regulation | 10 | 1 | |
| Glutathione peroxidase 1 (GPx1) inhibitors | 10 | 1 | |
| Estrogens | 10 | 1 | |
| Antilipemic Agents | 10 | 2 | |
| Androgens | 10 | 1 | |
| Gastric Inhibitory Polypeptide Up-Regulation | 10 | 1 | |
| CYP3A enzyme induction | 10 | 1 | |
| Neurotransmitter Uptake Inhibitors | 10 | 1 | |
| cAMP up-regulation | 10 | 1 | |
| Matrix Metalloproteinases Inhibitors | 10 | 6 | |
| Diacylglyceride acyltransferase 1 (DGAT1) Inhibition | 10 | 1 | |
| Oxytocin inducer | 10 | 1 | |
| Hormones | 10 | 1 | |
| Immunomodulatory: CD23+ Mature Macrophage Down-Regulation | 10 | 1 | |
| Insulin Antagonists | 10 | 1 | |
| Respiratory System Agents | 10 | 1 | |
| Central Nervous System Depressants | 10 | 1 | |
| Isoprostane Down-Regulation | 10 | 1 | |
| Immunostimulatory: IgA Production Up-Regulation | 10 | 1 | |
| Glucose transporter-2 (GLUT2) expression down-regulation | 10 | 6 | |
| Drug sparing | 10 | 1 | |
| Peptide YY (PYY) Down-regulation | 10 | 1 | |
| NOX2 inhibitor | 10 | 1 | |
| Immunomodulatory: Immunoglobulin G up-regulation | 10 | 1 | |
| Glucose transporter-2 (GLUT2) expression up-regulation | 10 | 1 | |
| Interleukin-3 upregulation | 10 | 1 | |
| Phosphorylase Kinase Inhibitors | 10 | 1 | |
| Immunomodulatory: Immunoglobulin M Up-Regulation | 10 | 1 | |
| Mitochondrial Superoxide Dismutase Upregulation | 10 | 6 | |
| PER2 Protein Expression Up-regulation | 10 | 1 | |
| Intracellular adhesion molecule down-regulation | 10 | 1 | |
| Adrenergic alpha-Antagonists | 11 | 2 | |
| Mitogen-activated protein kinase kinase 4 (MEK4) | 11 | 2 | |
| PI3K/Akt/signaling suppression | 11 | 6 | |
| Insulinotrophic | 11 | 7 | |
| 15-Lipoxygenase (15-LOX) Inhibitor | 11 | 8 | |
| Interleukin-1 receptor antagonist | 11 | 2 | |
| P16 Activation | 11 | 2 | |
| Tocolytic Agents | 11 | 2 | |
| Endocannabinoid down-regulation | 12 | 2 | |
| Immunomodulatory: T-Cell down-regulation | 12 | 2 | |
| Interleukin-13 Up-Regulation | 12 | 3 | |
| Vasopressin Inhibitor | 12 | 2 | |
| Metallothionein Up-regulation | 12 | 2 | |
| VEGFR3 inhibition | 12 | 3 | |
| Insulin Receptor Modulator | 12 | 2 | |
| Mucolytic | 12 | 2 | |
| Anti-edemic | 12 | 2 | |
| Immunomodulatory: Innate Immunity Up-Regulation | 12 | 2 | |
| Mitogen-activated protein kinase inhibitors | 12 | 3 | |
| Dopamine Agents | 12 | 2 | |
| Carminative | 12 | 2 | |
| Glutathione Peroxidase 1 (GPx1) Up-Regulation | 13 | 7 | |
| Leukotriene B4 downregulation | 13 | 4 | |
| Anti-collagenase | 13 | 3 | |
| Neocardiogenic | 14 | 11 | |
| Teratogens | 14 | 3 | |
| Cell Differentiation Inducer | 14 | 11 | |
| Glutathione S-transferase Inhibitor | 14 | 4 | |
| Paraptosis | 14 | 14 | |
| Neocardiogenic | 14 | 11 | |
| Hepatocyte growth factor (HGF) inhibitor | 15 | 4 | |
| Antithrombotic | 15 | 5 | |
| Antitubercular Agents | 15 | 5 | |
| Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor | 15 | 10 | |
| Glucose transporter-1 (GLUT1) expression down-regulation | 16 | 8 | |
| Peptide YY (PYY) Up-Regulation | 16 | 4 | |
| Topoisomerase I inhibitor | 17 | 15 | |
| Oncogene Suppressor | 17 | 13 | |
| P38 Mitogen-Activated Protein Kinase Modulator | 18 | 12 | |
| Adenosine Monophosphate (AMP)-activated Protein Kinase (AMPK | 18 | 4 | |
| Immune Enhancing Properties | 18 | 5 | |
| Tyrosinase inhibitors | 18 | 17 | |
| Matrix metalloproteinase-8 (MMP-8) inhibitor | 18 | 10 | |
| Insect Repellents | 19 | 12 | |
| Protease Inhibitors | 19 | 10 | |
| Matrix Metalloproteinase-12 (MMP-12) Inhibitor | 19 | 10 | |
| Remyelination | 20 | 11 | |
| Fatty Acid Oxidation | 20 | 2 | |
| Neurominidase Inhibitor | 20 | 23 | |
| Cholecystokinin Releaser | 20 | 2 | |
| Hematopoietic | 20 | 9 | |
| Adenosine deaminase inhibitor | 20 | 7 | |
| STAT3 Activation | 21 | 16 | |
| Gluconeogenesis Inhibitor | 21 | 15 | |
| Anticoagulants | 22 | 18 | |
| Viral Hemagglutinin Inhibitor | 22 | 16 | |
| Topoisomerase II Inhibitor | 22 | 20 | |
| Leptin Down-Regulation | 23 | 8 | |
| Monocyte chemotattractant protein-1 (MCP-1) Inhibitor | 23 | 4 | |
| Anti-cancer | 23 | 6 | |
| Natriuretic Agents | 23 | 4 | |
| Androgen Antagonists | 25 | 6 | |
| Detoxifier: Radionuclide Removal | 25 | 5 | |
| Nootropic Agents | 26 | 16 | |
| Interleukin-17 upregulation | 26 | 5 | |
| Glucose Uptake Optimization | 26 | 9 | |
| Prostaglandin Antagonists | 27 | 13 | |
| Vascular Endothelial Growth Factor C Inhibitor | 27 | 10 | |
| Fibrinolytic Agents | 28 | 7 | |
| Bax/Bcl2 Ratio: Decrease | 29 | 18 | |
| Protein Kinase Inhibitors | 29 | 20 | |
| Antipsychotic Agents | 30 | 13 | |
| Interleukin-8 upregulation | 30 | 3 | |
| HIV Protease Inhibitors | 31 | 21 | |
| Carcinogens | 31 | 6 | |
| Cholinesterase Inhibitors | 32 | 27 | |
| Dopaminergic | 32 | 10 | |
| Caspase-8 activation | 32 | 22 | |
| Aldose reductase inhibitor | 32 | 9 | |
| Matrix Metalloproteinase-7 (MMP-7) Inhibitor | 32 | 21 | |
| Interleukin-6 upregulation | 33 | 12 | |
| Spermatogenic | 34 | 12 | |
| Uterotonic | 34 | 11 | |
| Cholecystokinin (CCK) Up-regulation | 34 | 6 | |
| Enzyme Activators | 34 | 21 | |
| 5-alpha reductase inhibitor | 35 | 17 | |
| Analgesics: Non-Narcotic | 35 | 10 | |
| Antimycobacterial | 35 | 19 | |
| Antiurolithiatic | 35 | 11 | |
| Ghrelin Down-Regulation | 36 | 6 | |
| Glucagon Like Peptide 1 (GLP-1) Down-Regulation | 37 | 7 | |
| Interleukin-22 Downregulation | 37 | 18 | |
| Neuromodulatory | 37 | 7 | |
| Proton Pump Inhibitor | 38 | 14 | |
| Leukotriene Antagonists | 38 | 9 | |
| Insulin Down-Regulation | 38 | 7 | |
| Appetite Stimulants | 39 | 8 | |
| Fibroblast growth factor 21 upregulation | 40 | 16 | |
| Drug synergy | 40 | 11 | |
| Photosensitizing Agents | 41 | 22 | |
| Bcl-xL down-regulation | 41 | 30 | |
| Interferon Inducers | 41 | 10 | |
| Appetite Depressants | 42 | 13 | |
| Acid Blockers | 42 | 17 | |
| Laxative | 42 | 37 | |
| Histamine Antagonists | 45 | 17 | |
| Aromatase Inhibitors | 45 | 35 | |
| Histamine Antagonists | 45 | 17 | |
| Anabolic Agents | 45 | 12 | |
| 5-lipoxygenase Inhibitor | 46 | 29 | |
| Insecticidal | 46 | 24 | |
| 5-lipoxygenase Inhibitor | 46 | 29 | |
| Adiponectin Down-Regulation | 47 | 10 | |
| Reverse Transcriptase Inhibitors | 47 | 31 | |
| Interleukin-12 upregulation | 48 | 13 | |
| Chelating Agents | 48 | 25 | |
| Heat Shock Protein Down-Regulation | 49 | 28 | |
| Survivin Down-Regulation | 49 | 43 | |
| Lipolytic | 49 | 19 | |
| Lipoxygenase Inhibitors | 50 | 27 | |
| Bax/Bcl2 ratio: Increase | 50 | 40 | |
| Interleukin-2 upregulation | 51 | 13 | |
| Anti-Retroviral Agents | 51 | 20 | |
| Enzyme Inhibitors: Pancreatic Lipase | 53 | 24 | |
| Cholagogues and Choleretics | 54 | 12 | |
| Diuretics | 55 | 15 | |
| GABA Modulators | 55 | 23 | |
| Serotonergic | 56 | 12 | |
| Thermogenic | 57 | 9 | |
| Iron Chelating Agents | 58 | 20 | |
| Estrogen Receptor Modulators | 58 | 39 | |
| Proteasome Inhibitors | 59 | 40 | |
| Fertility Agents: Male | 60 | 92 | |
| Antiemetics | 60 | 6 | |
| Heme oxygenase-1 inducer | 60 | 41 | |
| Interferon-gamma (IFN-gamma) inducer | 60 | 20 | |
| Antiprotozoal Agents | 61 | 32 | |
| Vascular Endothelial Growth Factor Regulator | 62 | 35 | |
| Ergogenic | 63 | 8 | |
| Malonaldehyde (MDA) Down-Regulation | 65 | 17 | |
| Cyclooxygenase 1 Inhibitor | 65 | 56 | |
| Anti-Infective Agents | 66 | 47 | |
| Anti-Proliferative | 67 | 55 | |
| Aphrodisiac | 67 | 22 | |
| Multidrug Resistance Gene Modulators | 67 | 57 | |
| Xanthine oxidase inhibitor | 69 | 46 | |
| Tumor Necrosis Factor (TNF) Alpha Enhancer | 69 | 23 | |
| NF-E2-Related Factor-2 (Nrf2) Modulator | 70 | 40 | |
| Neurorestorative | 71 | 21 | |
| Caspase-9 Activation | 71 | 47 | |
| Anti-pyretic | 73 | 31 | |
| Cyclooxygenase Inhibitors | 74 | 45 | |
| Anti-thrombotic | 76 | 34 | |
| Bronchodilator Agents | 78 | 16 | |
| Immunosuppressive Agents | 80 | 51 | |
| Interleukin-23 Downregulation | 82 | 37 | |
| Quorum Sensing Inhibition | 83 | 79 | |
| Insulin-Like Growth Factor Inhibition/Downregulation | 86 | 19 | |
| Galactogogue | 87 | 11 | |
| Epidermal growth factor receptor (EGFR) inhibitor | 87 | 65 | |
| Hypoxia-inducible factor-1 (HIF-1) inhibitor | 89 | 33 | |
| Antimalarials | 90 | 67 | |
| Antitussive Agents | 92 | 21 | |
| Wnt/β-catenin pathway down-regulation | 94 | 56 | |
| Transforming growth factor beta (TGF-β) upregulation | 94 | 46 | |
| Phase II Detoxification Enzyme Inducer | 95 | 55 | |
| Telomerase Inhibitor | 95 | 65 | |
| Histone deacetylase inhibitor | 98 | 76 | |
| Calcium Channel Blockers | 98 | 29 | |
| Matrix metalloproteinase-1 (MMP-1) inhibitor | 99 | 80 | |
| Angiotensin-Converting Enzyme Inhibitors | 99 | 63 | |
| Interleukin-1 alpha downregulation | 102 | 59 | |
| Anti-Androgen | 104 | 26 | |
| DNA Repair Up-regulation | 105 | 30 | |
| Interleukin-10 upregulation | 105 | 357 | |
| Cardiotonic Agents | 106 | 10 | |
| Leishmanicidal | 118 | 106 | |
| Hypnotics and Sedatives | 122 | 49 | |
| Insulin-releasing | 122 | 60 | |
| Vascular Cell Adhesion Molecule-1 Inhibitor | 123 | 36 | |
| Anti-Cachexic Agents | 123 | 46 | |
| Appetite Suppresant | 126 | 21 | |
| Glucagon Like peptide 1 (GLP-1) Up-regulation | 131 | 36 | |
| Cyclin D1 Down-Regulation | 132 | 99 | |
| Heat Shock Protein Inducer | 133 | 53 | |
| Anti-HIV Agents | 133 | 95 | |
| Anti-Platelet | 137 | 49 | |
| Caspase-3 Activation | 137 | 90 | |
| Telomerase Upregulation | 137 | 36 | |
| interleukin-13 down-regulation | 140 | 69 | |
| Antispasmodic | 140 | 38 | |
| Interleukin-5 downregulation | 141 | 62 | |
| Anti-Tumor | 154 | 78 | |
| Neuroplasticity enhancement | 156 | 53 | |
| Fertility Agents: Female | 156 | 35 | |
| Antioxidant Effects | 157 | 44 | |
| Anti-Adipogenic | 164 | 103 | |
| Antimutagenic Agents | 164 | 133 | |
| Osteogenic | 167 | 64 | |
| Matrix metalloproteinase-3 (MMP-3) inhibitor | 169 | 96 | |
| Acetylcholinesterase Inhibitor | 170 | 124 | |
| Interleukin-4 upregulation | 171 | 64 | |
| Interleukin-2 Downregulation | 172 | 70 | |
| Interleukin-12 downregulation | 174 | 73 | |
| Alpha-amylase inhibitor | 175 | 167 | |
| Secretagogue | 178 | 38 | |
| Vascular Endothelial Growth Factor A Inhibitor | 179 | 120 | |
| Chondroprotective | 184 | 95 | |
| Neuritogenic | 185 | 101 | |
| Interleukin-17 downregulation | 193 | 165 | |
| Prostaglandin PGE2 downregulation | 194 | 89 | |
| Angiogenesis Inducing Agents | 197 | 95 | |
| P21 Activation | 197 | 137 | |
| Platelet Aggregation Inhibitors | 200 | 48 | |
| Cardiovascular Agents | 201 | 35 | |
| Postaglandin PGE2 downregulation | 202 | 178 | |
| Antiparasitic Agents | 208 | 177 | |
| Matrix Metalloproteinase-13 (MMP-13) Inhibitor | 209 | 97 | |
| Immunomodulatory: Th17 downregulation | 216 | 94 | |
| Adiponectin upregulation | 217 | 41 | |
| Nitric Oxide Enhancer | 261 | 82 | |
| Cytotoxic | 272 | 231 | |
| Dermatologic Agents | 272 | 35 | |
| Alpha-glucosidase inhibitor | 274 | 284 | |
| Autophagy Inhibitors | 274 | 172 | |
| Telomere Protective | 280 | 38 | |
| Radiosensitizer | 291 | 233 | |
| Neurogenesis | 291 | 152 | |
| Glutathione Upregulation | 299 | 108 | |
| Wnt/β-catenin signaling pathway modulation | 300 | 206 | |
| Wnt/β-catenin signaling pathway modulation | 300 | 206 | |
| Uricosuric Agents | 300 | 76 | |
| Interleukin-18 down-regulation | 312 | 154 | |
| Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor | 316 | 208 | |
| STAT3 Inhibitor | 317 | 213 | |
| Anti-Glycation Agents | 330 | 151 | |
| SIRT1 Activator | 343 | 167 | |
| Anti-Angiogenic | 347 | 272 | |
| Anti-atherogenic | 348 | 156 | |
| Interleukin-10 downregulation | 353 | 133 | |
| Interleukin-4 downregulation | 355 | 167 | |
| Catalase Up-Regulation | 368 | 149 | |
| Vasoprotective | 428 | 99 | |
| Antidiarrheals | 439 | 109 | |
| Anti-Allergic Agents | 442 | 207 | |
| Anti-Asthmatic Agents | 453 | 132 | |
| Regenerative | 459 | 195 | |
| Hypotensive | 467 | 63 | |
| Anxiolytic | 475 | 66 | |
| Angiogenesis Inhibitors | 488 | 452 | |
| Antifungal Agents | 494 | 397 | |
| Transforming growth factor beta (TGF-β) inhibitor | 495 | 254 | |
| Nitric Oxide Inhibitor | 498 | 342 | |
| Genoprotective | 513 | 197 | |
| Autophagy Up-regulation | 518 | 506 | |
| Pancreato Protective Agents | 521 | 283 | |
| Anti-Ulcer Agents | 523 | 265 | |
| Interferon Gamma Reducer | 555 | 208 | |
| Vascular Endothelial Growth Factor Inhibitors | 578 | 314 | |
| Interleukin-8 downregulation | 581 | 368 | |
| Tumor Suppressor Protein p53 Upregulation | 585 | 524 | |
| Vasodilator Agents | 626 | 207 | |
| Detoxifier | 644 | 244 | |
| Antinoceceptive | 647 | 265 | |
| Cytoprotective | 659 | 385 | |
| Brain-derived neurotrophic factor modulator | 672 | 250 | |
| Anticonvulsants | 678 | 253 | |
| Bcl-2 protein down-regulation | 683 | 508 | |
| Enzyme Inhibitors | 692 | 392 | |
| Photoprotective | 717 | 279 | |
| Matrix metalloproteinase-2 (MMP-2) inhibitor | 727 | 565 | |
| Immunostimulatory | 730 | 226 | |
| Matrix metalloproteinase-9 (MMP-9) inhibitor | 786 | 674 | |
| Gastroprotective | 955 | 655 | |
| Chemosensitizer | 1124 | 1199 | |
| Insulin Sensitizers | 1185 | 373 | |
| Heme oxygenase-1 up-regulation | 1206 | 703 | |
| Antimicrobial | 1209 | 761 | |
| Prophylactic Agents | 1333 | 278 | |
| MicroRNA modulator | 1525 | 884 | |
| Cyclooxygenase 2 Inhibitors | 1589 | 1223 | |
| Radioprotective | 1668 | 638 | |
| Cell cycle arrest | 1678 | 1656 | |
| Osteoprotective | 1840 | 616 | |
| Antineoplastic Agents | 1847 | 1392 | |
| Anticarcinogenic Agents | 1890 | 1004 | |
| Anti-Fibrotic | 1896 | 888 | |
| Antiviral Agents | 1957 | 1615 | |
| Anti-metastatic | 1972 | 2051 | |
| Superoxide Dismutase Up-regulation | 2090 | 812 | |
| Chemotherapeutic | 2328 | 1407 | |
| Renoprotective | 2404 | 1762 | |
| Malondialdehyde Down-regulation | 2775 | 897 | |
| Nrf2 activation | 2881 | 1640 | |
| Anti-Bacterial Agents | 2894 | 1816 | |
| Anti-Apoptotic | 2905 | 2774 | |
| Anti-Anxiety Agents | 2913 | 735 | |
| Interleukin-1 beta downregulation | 3041 | 2595 | |
| Anticholesteremic Agents | 3078 | 646 | |
| Gastrointestinal Agents | 3145 | 1960 | |
| Analgesics | 3498 | 943 | |
| NF-kappaB Inhibitor | 3536 | 3169 | |
| Chemoprotective Agents | 3706 | 1442 | |
| Immunomodulatory | 4048 | 2154 | |
| Antihypertensive Agents | 4527 | 950 | |
| Antidepressive Agents | 4882 | 1328 | |
| Interleukin-6 Downregulation | 5029 | 3255 | |
| Hepatoprotective | 5098 | 3517 | |
| Hypolipidemic | 5358 | 1880 | |
| Hypoglycemic Agents | 5366 | 1911 | |
| Chemopreventive | 5374 | 2086 | |
| Cardioprotective | 5377 | 2655 | |
| Tumor Necrosis Factor (TNF) Alpha Inhibitor | 6736 | 4342 | |
| Antiproliferative | 6801 | 6958 | |
| Apoptotic | 6986 | 6931 | |
| Neuroprotective Agents | 10404 | 6995 | |
| Anti-Inflammatory Agents | 20859 | 13987 | |
| Antioxidants | 21528 | 13231 | |
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