Focused Research Topics Garlic & Colon Cancer

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Associated Topics included in this Focused Research

Allicin Garlic

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6 Research Articles in Total

Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.

Pubmed Data : J Nutr. 2006 Mar;136(3 Suppl):816S-820S. PMID: 16484572
Article Published Date : Mar 01, 2006
Authors : Hideki Ishikawa, Tomoko Saeki, Toru Otani, Takaichiro Suzuki, Kojiro Shimozuma, Hoyoku Nishino, Sanae Fukuda, Kanehisa Morimoto
Study Type : Human Study
Additional Links
Substances : Garlic : CK(824) : AC(274)
Diseases : Colon Cancer : CK(749) : AC(430), Liver Cancer : CK(1235) : AC(462), Low Immune Function: Natural Killer Cells : CK(121) : AC(24), Pancreatic Cancer : CK(890) : AC(260)
Additional Keywords : Drug Side Effect Attenuation : CK(251) : AC(49), Plant Extracts : CK(7645) : AC(2539)

Allicin, the major ingredient of freshly crushed garlic, inhibits cancer cell proliferation.

Pubmed Data : Nutr Cancer. 2000;38(2):245-54. PMID: 11525603
Article Published Date : Jan 01, 2000
Authors : K Hirsch, M Danilenko, J Giat, T Miron, A Rabinkov, M Wilchek, D Mirelman, J Levy, Y Sharoni
Study Type : In Vitro Study
Additional Links
Substances : Allicin : CK(48) : AC(25), Garlic : CK(824) : AC(274)
Diseases : Breast Cancer : CK(3592) : AC(1064), Colon Cancer : CK(749) : AC(430), Endometrial Cancer : CK(307) : AC(53)
Pharmacological Actions : Antiproliferative : CK(2546) : AC(1685), Apoptotic : CK(2958) : AC(2075), Cell cycle arrest : CK(810) : AC(612)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

Allicin purified from fresh garlic cloves induces programmed cell death in colon cancer cells.

Pubmed Data : Nutr Cancer. 2010;62(7):947-57. PMID: 20924970
Article Published Date : Jan 01, 2010
Authors : Wolf Bat-Chen, Tal Golan, Irena Peri, Zvi Ludmer, Betty Schwartz
Study Type : In Vitro Study
Additional Links
Substances : Allicin : CK(48) : AC(25)
Diseases : Colon Cancer : CK(749) : AC(430)
Pharmacological Actions : Antiproliferative : CK(2546) : AC(1685), Apoptotic : CK(2958) : AC(2075), NF-E2-Related Factor-2 (Nrf2) Modulator : CK(48) : AC(26)

High temperature- and pressure-treated garlic inhibits chemically-induced precancerous cellular changes in the rat colon.

Pubmed Data : Asian Pac J Cancer Prev. 2009;10(5):827-31. PMID: 20104973
Article Published Date : Jan 01, 2009
Authors : Takeshi Chihara, Kan Shimpo, Takaaki Kaneko, Hidehiko Beppu, Akiko Tomatsu, Shigeru Sonoda
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(824) : AC(274)
Diseases : Colon Cancer : CK(749) : AC(430)
Pharmacological Actions : Chemopreventive : CK(2835) : AC(787)

Diallyl disulfide (DADS), a major organosulfur compound of garlic oil, is capable of inhibiting colon cancer cells.

Pubmed Data : Oncol Rep. 2008 Jan;19(1):275-80. PMID: 18097607
Article Published Date : Jan 01, 2008
Authors : Hong Jae Jo, Ju Dong Song, Kang Mi Kim, Yong Hoon Cho, Ki Hyung Kim, Young Chul Park
Study Type : In Vitro Study
Additional Links
Substances : Garlic : CK(824) : AC(274)
Diseases : Colon Cancer : CK(749) : AC(430)
Pharmacological Actions : Antineoplastic Agents : CK(1158) : AC(639), Antiproliferative : CK(2546) : AC(1685), Tumor Suppressor Protein p53 Upregulation : CK(293) : AC(202)

A garlic extract, Diallyl disulfide, modulates gene expression in colon cells, inhibiting tumorigenesis.

Pubmed Data : Carcinogenesis. 2004 Jul;25(7):1227-36. Epub 2004 Feb 19. PMID: 14976134
Article Published Date : Jul 01, 2004
Authors : Nathalie Druesne, Anthony Pagniez, Camille Mayeur, Muriel Thomas, Claire Cherbuy, Pierre-Henri Duée, Paule Martel, Catherine Chaumontet
Study Type : In Vitro Study
Additional Links
Substances : Garlic : CK(824) : AC(274)
Diseases : Colon Cancer : CK(749) : AC(430)
Additional Keywords : Epigenetic Modification : CK(220) : AC(90), Histone Acetylation : CK(1) : AC(1)

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