Focused Research Topics Garlic & Antioxidants

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Allicin Garlic

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37 Research Articles in Total

"Chronic nicotine toxicity is prevented by aqueous garlic extract."

Pubmed Data : Plant Foods Hum Nutr. 2005 Jun ;60(2):77-86. PMID: 16021835
Article Published Date : Jun 01, 2005
Authors : Göksel Sener, A Ozer Sehirli, Yeşim Ipçi, Sule Cetinel, Esra Cikler, Nursal Gedik
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Nicotine/Tobacco Toxicity : CK(107) : AC(38), Oxidative Stress : CK(3871) : AC(1382)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Malondialdehyde Down-regulation : CK(554) : AC(152)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)
Problem Substances : Nicotine : CK(71) : AC(18)
Adverse Pharmacological Actions : Oxidant : CK(113) : AC(43)

Aged garlic extract and grape seed proanthocyanidin protect against doxorubicin-induced cardiotoxicity.

Pubmed Data : Can J Physiol Pharmacol. 2009 Aug;87(8):633-40. PMID: 19767888
Article Published Date : Aug 01, 2009
Authors : Erkan Demirkaya, Aslihan Avci, Vural Kesik, Yildirim Karslioglu, Emin Oztas, Erol Kismet, Erdal Gokcay, Ilker Durak, Vedat Koseoglu
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226), Grape Seed Extract : CK(316) : AC(88)
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin : CK(132) : AC(56)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682)
Additional Keywords : Drug: Doxorubicin : CK(166) : AC(62), Plant Extracts : CK(7645) : AC(2539), Proanthocyanidins : CK(203) : AC(54)

Aged garlic extract has the ability to ameliorate kidney damage in diabetic rats and the renoprotective effect of AGE may be attributed to its anti-glycation and hypolipidemic activities.

Pubmed Data : Indian J Pharmacol. 2013 Jan-Feb;45(1):18-23. PMID: 23543654
Article Published Date : Dec 31, 2012
Authors : T M Shiju, N G Rajesh, Pragasam Viswanathan
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Diabetic Nephropathy : CK(140) : AC(54)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Hypoglycemic Agents : CK(1446) : AC(342), Renoprotective : CK(572) : AC(254)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

Allylmethylsulfide (AMS), a volatile organosulfur derivative from garlic has radioprotective properties.

Pubmed Data : J Med Food. 2009 Jun;12(3):542-51. PMID: 19627202
Article Published Date : Jun 01, 2009
Authors : Eun Kyeong Lee, Sang Woon Chung, Ji Young Kim, Ji Min Kim, Hyoung-Sam Heo, Hyun Ae Lim, Mi Kyung Kim, Stephen Anton, Takako Yokozawa, Hae Young Chung
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Lipid Peroxidation : CK(695) : AC(255), Radiation Induced Illness : CK(1046) : AC(264)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Cyclooxygenase 2 Inhibitors : CK(464) : AC(272), NF-kappaB Inhibitor : CK(1114) : AC(694), Radioprotective : CK(756) : AC(262), Vascular Cell Adhesion Molecule-1 Inhibitor : CK(117) : AC(30)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

Garlic extract prevents selenite-induced cataractogenesis in rats.

Pubmed Data : J Ocul Pharmacol Ther. 2009 Oct;25(5):395-400. PMID: 19857100
Article Published Date : Oct 01, 2009
Authors : Alireza Javadzadeh, Amir Ghorbanihaghjo, Sara Arami, Nadereh Rashtchizadeh, Mehran Mesgari, Mandana Rafeey, Yadollah Omidi
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Cataract : CK(196) : AC(61)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539), Sodium Selenite : CK(49) : AC(19)

Garlic prevents methyl mercury-induced cytotoxicity.

Pubmed Data : Food Chem Toxicol. 2010 Jan;48(1):417-21. Epub 2009 Oct 29. PMID: 19879309
Article Published Date : Jan 01, 2010
Authors : F H Abdalla, L P Bellé, K S De Bona, P E R Bitencourt, A S Pigatto, M B Moretto
Study Type : In Vitro Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Mercury Poisoning : CK(228) : AC(65)
Pharmacological Actions : Adenosine deaminase inhibitor : CK(16) : AC(5), Antioxidants : CK(7529) : AC(2682)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

Garlic reduces the neurotoxicity associated with mercury exposure.

Pubmed Data : Regul Toxicol Pharmacol. 2006 Dec;46(3):163-6. Epub 2006 Aug 4. PMID: 19413661
Article Published Date : Dec 01, 2006
Authors : Luziane Potrich Bellé, Karine Santos De Bona, Faida Husein Abdalla, Victor Camera Pimentel, Aline Schirmer Pigatto, Maria Beatriz Moretto
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Mercury Poisoning : CK(228) : AC(65)
Pharmacological Actions : Adenosine deaminase inhibitor : CK(16) : AC(5), Antioxidants : CK(7529) : AC(2682), Neuroprotective Agents : CK(2360) : AC(1099)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

Garlic seems safer clinically and as effective as d-penicillamine for removing lead from the body.

Pubmed Data : Basic Clin Pharmacol Toxicol. 2012 May ;110(5):476-81. Epub 2011 Dec 29. PMID: 22151785
Article Published Date : Apr 30, 2012
Authors : Sina Kianoush, Mahdi Balali-Mood, Seyed Reza Mousavi, Valiollah Moradi, Mahmoud Sadeghi, Bita Dadpour, Omid Rajabi, Mohammad Taghi Shakeri
Study Type : Human Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Lead Poisoning : CK(205) : AC(60)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Chelating Agents : CK(12) : AC(1), Detoxifier : CK(408) : AC(131)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539), Superiority of Natural Substances versus Drugs : CK(1316) : AC(251)
Problem Substances : Lead : CK(167) : AC(32)

Garlic, especially in its raw form, is a platelet inhibitor.

Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 1999 Jan;60(1):43-7. PMID: 10319916
Article Published Date : Jan 01, 1999
Authors : M Ali, T Bordia, T Mustafa
Study Type : In Vitro Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Thrombosis : CK(316) : AC(81)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Platelet Aggregation Inhibitors : CK(186) : AC(40)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

L-arginine augments the antioxidant effect of garlic against acetic acid-induced ulcerative colitis in rats.

Pubmed Data : Pak J Pharm Sci. 2009 Oct;22(4):373-80. PMID: 19783514
Article Published Date : Oct 01, 2009
Authors : Gamal Eldin I Harisa, Osama M Abo-Salem, El-Sayed M El-Sayed, Ehab I Taha, Nermin El-Halawany
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(1012) : AC(176), Garlic : CK(722) : AC(226)
Diseases : Ulcerative Colitis : CK(295) : AC(59)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682)
Additional Keywords : Natural Substance Synergy : CK(540) : AC(249), Plant Extracts : CK(7645) : AC(2539)

Onion and garlic extracts lessen cadmium-induced kidney damage in rats.

Pubmed Data : Biometals. 2008 Dec;21(6):623-33. Epub 2008 Jun 3. PMID: 18521705
Article Published Date : Dec 01, 2008
Authors : Stephen M Suru
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226), Onion : CK(235) : AC(57)
Diseases : Cadmium Poisoning : CK(131) : AC(62)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Renoprotective : CK(572) : AC(254)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

Raw and boiled garlic enhances plasma antioxidant activity and improves plasma lipid metabolism in cholesterol-fed rats.

Pubmed Data : Life Sci. 2006 Jan 2;78(6):655-63. Epub 2005 Sep 13. PMID: 16165163
Article Published Date : Jan 02, 2006
Authors : Shela Gorinstein, Hanna Leontowicz, Maria Leontowicz, Jerzy Drzewiecki, Katarzyna Najman, Elena Katrich, Dinorah Barasch, Kazutaka Yamamoto, Simon Trakhtenberg
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : High Cholesterol : CK(1774) : AC(271)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539), Raw versus Cooked : CK(69) : AC(13)

The use of Allyl disulfide supplementation after major hepatectomy has a positive impact on liver regeneration, proliferation and oxidative damage.

Pubmed Data : Chirurgia (Bucur). 2015 Mar-Apr;110(2):117-22. PMID: 26011832
Article Published Date : Feb 28, 2015
Authors : M Battal, A Kartal, B Citgez, B Yilmaz, A Akcakaya, O Karatepe,
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Inflammation : CK(3240) : AC(882), Liver Surgery : CK(16) : AC(4), Oxidative Stress : CK(3871) : AC(1382)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Regenerative : CK(52) : AC(28)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

"Garlic and vitamin E provides antioxidant defence in tissues of female rats treated with nicotine."

Pubmed Data : Niger J Physiol Sci. 2011 ;26(1):103-7. Epub 2011 Nov 23. PMID: 22314996
Article Published Date : Jan 01, 2011
Authors : B O Iranloye, G O Oludare
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226), Vitamin E : CK(1656) : AC(290)
Diseases : Nicotine/Tobacco Toxicity : CK(107) : AC(38), Oxidative Stress : CK(3871) : AC(1382)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682)

A combination of GAR and S-VACE can be a novel therapy for the management of lung diseases in humans.

Pubmed Data : Drug Metabol Personal Ther. 2016 Mar 1 ;31(1):47-54. PMID: 26943616
Article Published Date : Feb 29, 2016
Authors : Jacob K Akintunde, Olakunle Enock Bolarin, Daniel G Akintunde
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226), Selenium : CK(784) : AC(139), Vitamin A : CK(498) : AC(77), Vitamin C : CK(1957) : AC(404), Vitamin E : CK(1656) : AC(290)
Diseases : Lung Damage : CK(14) : AC(7), Lung Diseases : CK(38) : AC(9)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682)
Problem Substances : Lisinopril : CK(3) : AC(1)

Allicin may be useful in reducing oxidative stress, inflammation, vascular dysfunction, and the aortic pathology in hypercholesterolemic rabbits.

Pubmed Data : Can J Physiol Pharmacol. 2015 Aug 14:1-9. Epub 2015 Aug 14. PMID: 26618400
Article Published Date : Aug 13, 2015
Authors : Ahmed R El-Sheakh, Hamdy A Ghoneim, Ghada M Suddek, El Sayed M Ammar
Study Type : Animal Study
Additional Links
Substances : Allicin : CK(48) : AC(25)
Diseases : Endothelial Dysfunction : CK(1210) : AC(237), Inflammation : CK(3240) : AC(882), Obesity : CK(3022) : AC(467), Oxidative Stress : CK(3871) : AC(1382)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630), Antioxidants : CK(7529) : AC(2682)

Both resveratrol and garlic have similar property to increase insulin secretion from beta cells.

Pubmed Data : Front Pharmacol. 2016 ;7:360. Epub 2016 Aug 13. PMID: 27790139
Article Published Date : Dec 31, 2015
Authors : Gagandeep Kaur, Raju Padiya, Ramu Adela, Uday K Putcha, G S Reddy, B R Reddy, K P Kumar, Sumana Chakravarty, Sanjay K Banerjee
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226), Resveratrol : CK(1283) : AC(746)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301), Diabetic Complications : CK(1563) : AC(333)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Hepatoprotective : CK(1387) : AC(594), Pancreato Protective Agents : CK(40) : AC(23)
Additional Keywords : Superiority of Natural Substances versus Drugs : CK(1316) : AC(251)

Curcumin, capsaicin and garlic inhibit adverse blood and liver changes associated wtih a high-fat diet in rats.

Pubmed Data : Ann Nutr Metab. 2004 Sep-Oct;48(5):314-20. Epub 2004 Oct 1. PMID: 15467281
Article Published Date : Sep 01, 2004
Authors : R K Kempaiah, K Srinivasan
Study Type : Animal Study
Additional Links
Substances : Capsaicin : CK(129) : AC(55), Curcumin : CK(4803) : AC(2175), Garlic : CK(722) : AC(226)
Diseases : Hyperlipidemia : CK(670) : AC(155), Liver Disease : CK(145) : AC(41), Oxidative Stress : CK(3871) : AC(1382)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Hepatoprotective : CK(1387) : AC(594)

Curcumin, capsaicin, and garlic have a beneficial effect in the red blood cells and liver of cholesterol fed rats.

Pubmed Data : Acta Pharmacol Sin. 2007 Oct;28(10):1559-65. PMID: 15296079
Article Published Date : Oct 01, 2007
Authors : R K Kempaiah, K Srinivasan
Study Type : Animal Study
Additional Links
Substances : Capsaicin : CK(129) : AC(55), Curcumin : CK(4803) : AC(2175), Garlic : CK(722) : AC(226)
Diseases : High Cholesterol : CK(1774) : AC(271)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Cardioprotective : CK(1596) : AC(409), Hepatoprotective : CK(1387) : AC(594)

Dimethyl trisulfide is a promising next-generation countermeasure for cyanide intoxication.

Pubmed Data : Toxicol Ind Health. 2016 Mar 3. Epub 2016 Mar 3. PMID: 26939832
Article Published Date : Mar 02, 2016
Authors : Gary A Rockwood, David E Thompson, Ilona Petrikovics
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Broccoli : CK(962) : AC(298), Dimethyl trisulfide (DMTS) : CK(2) : AC(1), Garlic : CK(722) : AC(226), Onion : CK(235) : AC(57)
Diseases : Cyanide Poisoning : CK(30) : AC(8)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682)
Additional Keywords : Superiority of Natural Substances versus Drugs : CK(1316) : AC(251)

Garlic activates SIRT-3 to prevent cardiac oxidative stress and mitochondrial dysfunction in diabetes.

Pubmed Data : Life Sci. 2016 Nov 1 ;164:42-51. Epub 2016 Aug 31. PMID: 27590611
Article Published Date : Oct 31, 2016
Authors : Md Razia Sultana, Pankaj K Bagul, Parameshwar B Katare, Soheb Anwar Mohammed, Raju Padiya, Sanjay K Banerjee
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Diabetic Complications : CK(1563) : AC(333), Mitochondrial Dysfunction : CK(225) : AC(91)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682)

Garlic and onion protect against nicotine-induced lipid peroxidation.

Pubmed Data : Vet Hum Toxicol. 1999 Oct;41(5):316-9. PMID: 10509436
Article Published Date : Oct 01, 1999
Authors : A Helen, C R Rajasree, K Krishnakumar, K T Augusti, P L Vijayammal
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226), Onion : CK(235) : AC(57)
Diseases : Nicotine/Tobacco Toxicity : CK(107) : AC(38), Smoking : CK(676) : AC(102), Tobacco Toxicity : CK(106) : AC(18)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Cardioprotective : CK(1596) : AC(409)

Garlic has hepato- and reno-protective effects against sodium-nitrate induced oxdiative stress.

Pubmed Data : Int J Biol Sci. 2009;5(3):249-55. Epub 2009 Mar 10. PMID: 19305642
Article Published Date : Jan 01, 2009
Authors : Hanaa A Hassan, Sherif M El-Agmy, Rajiv L Gaur, Augusta Fernando, Madhwa Hg Raj, Allal Ouhtit
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Oxidative Stress : CK(3871) : AC(1382), Sodium nitrate toxicity : CK(15) : AC(8)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682)

Garlic may effectively modulate antioxidants status in the blood and heart of streptozotocin induced-diabetic rats.

Pubmed Data : Acta Physiol Hung. 2015 Dec ;102(4):380-90. PMID: 26690030
Article Published Date : Nov 30, 2015
Authors : R Naderi, G Mohaddes, M Mohammadi, A Alihemmati, R Badalzadeh, R Ghaznavi, R Ghyasi, Sh Mohammadi
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301), Oxidative Stress : CK(3871) : AC(1382)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Cardioprotective : CK(1596) : AC(409), Catalase Up-Regulation : CK(118) : AC(42), Superoxide Dismutase Up-regulation : CK(530) : AC(174)

Garlic oil could be a promising protective agent recommended for ulcerative colitis patients.

Pubmed Data : Life Sci. 2016 Feb 1 ;146:40-51. Epub 2016 Jan 11. PMID: 26780265
Article Published Date : Jan 31, 2016
Authors : Mohamed Balaha, Samah Kandeel, Walaa Elwan
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Colitis: Ulcerative : CK(104) : AC(16)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630), Antioxidants : CK(7529) : AC(2682)
Additional Keywords : Plant Oils : CK(55) : AC(24)

Garlic powder protects against dichromate-induced oxidative stress and kidney damage.

Pubmed Data : Food Chem Toxicol. 2008 Feb;46(2):619-27. Epub 2007 Sep 18. PMID: 17950512
Article Published Date : Feb 01, 2008
Authors : José Pedraza-Chaverri, Paola Yam-Canul, Yolanda I Chirino, Dolores Javier Sánchez-González, Claudia María Martínez-Martínez, Cristino Cruz, Omar N Medina-Campos
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Kidney Damage : CK(193) : AC(64), Oxidative Stress : CK(3871) : AC(1382)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Renoprotective : CK(572) : AC(254)

Garlic prevents sodium nitrate induced neurotoxicty and oxidative stress in male rats.

Pubmed Data : Food Chem Toxicol. 2010 May 10. Epub 2010 May 10. PMID: 20457208
Article Published Date : May 10, 2010
Authors : Hanaa A Hassan, Hani S Hafez, Fawzia E Zeghebar
Study Type : Animal Study
Additional Links
Substances : Garlic : CK(722) : AC(226)
Diseases : Sodium nitrate toxicity : CK(15) : AC(8)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Neuroprotective Agents : CK(2360) : AC(1099)

Supplementation with alpha lipoic acid and garlic aqueous extracts improved the alternations brought on by organophosphorus pesticides.

Pubmed Data : Int J Clin Exp Med. 2015 ;8(5):7689-700. Epub 2015 May 15. PMID: 26221319
Article Published Date : Dec 31, 2014
Authors : Manal Ea Elhalwagy, Nevine S Darwish, Dina A Shokry, Aly Ge Abd El-Aal, Sherif H Abd-Alrahman, Abd-Alhamed Nahas, Reem M Ziada
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid : CK(476) : AC(116), Garlic : CK(722) : AC(226)
Diseases : Pesticide-Induced Toxicity: Organophosphates : CK(21) : AC(8)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Cytoprotective : CK(190) : AC(94)
Problem Substances : Organophosphate Pesticides : CK(10) : AC(1)

α-lipoic acid and garlic had beneficial results on biomarkers of oxidative stress and inflammation in rabbits exposed to oxidized nutrition oils.

Pubmed Data : Biomed Res Int. 2015 ;2015:827879. Epub 2015 Nov 8. PMID: 26634212
Article Published Date : Dec 31, 2014
Authors : Jolanta Zalejska-Fiolka, Tomasz Wielkoszyński, Wojciech Rokicki, Natalia Dąbrowska, Joanna Katarzyna Strzelczyk, Aleksandra Kasperczyk, Aleksander Owczarek, Urszula Błaszczyk, Sławomir Kasperczyk, Barbara Stawiarska-Pięta, Ewa Birkner, Andrzej Gamian
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid : CK(476) : AC(116), Garlic : CK(722) : AC(226)
Diseases : Inflammation : CK(3240) : AC(882), Oxidative Stress : CK(3871) : AC(1382)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630), Antioxidants : CK(7529) : AC(2682)

This document is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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