Focused Research Topics Turmeric & Diabetes Mellitus: Type 1

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Associated Topics included in this Focused Research

Curcumin Curcumin: Lipidated Curcuminoids Curcumol Demethoxycurcumin Tetrahydrocurcumin Turmeric Turmeric: Fermented Turmeric: Topical Turmerin Turmerones

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View the Evidence
13 Research Articles in Total

Curcumin protects pancreatic islet cells and chemically-induced type 1 diabetes.

Pubmed Data : Br J Pharmacol. 2008 Nov;155(5):702-13. Epub 2008 Aug 11. PMID: 18695642
Article Published Date : Nov 01, 2008
Authors : M Kanitkar, K Gokhale, S Galande, R R Bhonde
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4803) : AC(2175)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301), Oxidative Stress : CK(3871) : AC(1382)
Pharmacological Actions : Apoptotic : CK(2958) : AC(2075), NF-kappaB Inhibitor : CK(1114) : AC(694)
Additional Keywords : Beta Cell Protection : CK(61) : AC(25)

A novel curcumin derivative regenerates pancreatic islets in experimental type-1 diabetes in rats (long term study).

Pubmed Data : Diabetol Metab Syndr. 2013 ;5(1):75. Epub 2013 Nov 26. PMID: 24279645
Article Published Date : Dec 31, 2012
Authors : Mohamed T Abdel Aziz, Mohamed F El-Asmar, Ameen M Rezq, Soheir M Mahfouz, Mohamed A Wassef, Hanan H Fouad, Hanan H Ahmed, Fatma M Taha
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4803) : AC(2175)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301), Diabetes Mellitus: Type 1: Prevention : CK(255) : AC(50)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682), Regenerative : CK(52) : AC(28)
Additional Keywords : Beta Cell Regeneration : CK(78) : AC(29)

Prophylactic use of curcumin may effectively rescue pancreatic islets from damage without affecting the normal function of these cellular structures.

Pubmed Data : BJU Int. 2002 Jun;89(9):829-34. PMID: 17900558
Article Published Date : Jun 01, 2002
Authors : Kanitkar Meghana, Galande Sanjeev, Bhonde Ramesh
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4803) : AC(2175)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301)
Pharmacological Actions : Antioxidants : CK(7529) : AC(2682)
Additional Keywords : Beta Cell Protection : CK(61) : AC(25)

Curcumin ameliorated skeletal muscle atrophy in DM mice by inhibiting protein ubiquitination, inflammatory cytokines and oxidative stress.

Pubmed Data : Exp Physiol. 2015 May 22. Epub 2015 May 22. PMID: 25998196
Article Published Date : May 21, 2015
Authors : Taisuke Ono, Shingo Takada, Shintaro Kinugawa, Tadashi Suga, Mochamad A Sobirin, Kagami Hirabayashi, Masashige Takahashi, Arata Fukushima, Tsuneaki Homma, Takashi Yokota, Shouji Matsushima, Hiroyuki Tsutsui
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4803) : AC(2175)
Diseases : Diabetes: Oxidative Stress : CK(131) : AC(40), Diabetes Mellitus: Type 1 : CK(1130) : AC(301), Inflammation : CK(3240) : AC(882), Muscle Atrophy : CK(105) : AC(35)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630), Interleukin-1 beta downregulation : CK(478) : AC(205), NF-kappaB Inhibitor : CK(1114) : AC(694), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(1823) : AC(669)
Additional Keywords : Significant Treatment Outcome : CK(3038) : AC(366)

Combined treatment of tetrahydrocurcumin and chlorogenic acid exerts potential antihyperglycemic effect on type 1 diabetic rats.

Pubmed Data : Gen Physiol Biophys. 2010 Mar;29(1):23-30. PMID: 20371877
Article Published Date : Mar 01, 2010
Authors : Krishnamoorthy Karthikesan, Leelavinothan Pari, Venugopal P Menon
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid : CK(13) : AC(7), Curcumin : CK(4803) : AC(2175)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301)
Pharmacological Actions : Hypoglycemic Agents : CK(1446) : AC(342)
Additional Keywords : Natural Substance Synergy : CK(540) : AC(249)

Curcumin has an insulin releasing effect in rat-isolated pancreatic islets.

Pubmed Data : Angiology. 2010 Aug;61(6):557-66. Epub 2010 Apr 14. PMID: 20395228
Article Published Date : Aug 01, 2010
Authors : Mohamed T Abdel Aziz, Mohamed F El-Asmar, Essam G El Nadi, Mohamed A Wassef, Hanan H Ahmed, Laila A Rashed, Eman M Obaia, Dina Sabry, Amira A Hassouna, Ahmed T Abdel Aziz
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4803) : AC(2175)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301), Insulin: Low : CK(24) : AC(4)
Pharmacological Actions : Insulin-releasing : CK(62) : AC(28)

Curcumin might be used to prevent neuronal damage in the retina of patients with diabetes mellitus.

Pubmed Data : J Ocul Pharmacol Ther. 2015 Jul 24. Epub 2015 Jul 24. PMID: 26207889
Article Published Date : Jul 23, 2015
Authors : Jun Li, Peipei Wang, Yanxia Zhu, Zhen Chen, Tianyan Shi, Wensheng Lei, Songping Yu
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4803) : AC(2175)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301), Diabetic Complications : CK(1563) : AC(333)
Pharmacological Actions : Anti-Apoptotic : CK(384) : AC(212), Neuroprotective Agents : CK(2360) : AC(1099)

Curcumin preserves pancreatic islet cell survival and transplantation efficiency.

Pubmed Data : Life Sci. 2008 Jan 16;82(3-4):182-9. Epub 2007 Nov 21. PMID: 18093618
Article Published Date : Jan 16, 2008
Authors : Meghana Kanitkar, Ramesh R Bhonde
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4803) : AC(2175)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301), Organ Transplantation: Pancreatic Islet Cells : CK(8) : AC(5)
Additional Keywords : Beta Cell Protection : CK(61) : AC(25), Beta Cell Regeneration : CK(78) : AC(29)

Curcumin stimulates regeneration of pancreatic islet cells in a type 1 diabetes mouse model.

Pubmed Data : J Med Assoc Thai. 2010 Nov;93 Suppl 6:S152-9. PMID: 21280528
Article Published Date : Nov 01, 2010
Authors : Malee Chanpoo, Hattaya Petchpiboonthai, Busaba Panyarachun, Vipavee Anupunpisit
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4803) : AC(2175)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301)
Additional Keywords : Beta Cell Regeneration : CK(78) : AC(29)

Curcumin's blood sugar lowering effect may be due to its inhibitory effect on hepatic gluconeogenesis.

Pubmed Data : Biochem Biophys Res Commun. 2009 Oct 16;388(2):377-82. Epub 2009 Aug 8. PMID: 19665995
Article Published Date : Oct 16, 2009
Authors : Teayoun Kim, Jessica Davis, Albert J Zhang, Xiaoming He, Suresh T Mathews
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4803) : AC(2175)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301), Diabetes Mellitus: Type 2 : CK(3572) : AC(624)
Pharmacological Actions : AMP-activated protein kinase modulation : CK(2) : AC(2), Gluconeogenesis Inhibitor : CK(19) : AC(14)
Additional Keywords : Metformin Alternatives : CK(19) : AC(6), Natural Substances Versus Drugs : CK(1698) : AC(302)

Turmeric and curcumin have anti-diabetic actions.

Pubmed Data : Plant Foods Hum Nutr. 2002;57(1):41-52. PMID: 11855620
Article Published Date : Jan 01, 2002
Authors : N Arun, N Nalini
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4803) : AC(2175)
Diseases : Diabetes: Glycation/A1C : CK(210) : AC(33), Diabetes Mellitus: Type 1 : CK(1130) : AC(301), Diabetes Mellitus: Type 2 : CK(3572) : AC(624)

Turmeric powder combined with milk as therapeutic properties in an animdal model of both type 1 and type 2 diabetes.

Pubmed Data : Indian J Clin Biochem. 2010 Apr ;25(2):175-81. Epub 2010 May 27. PMID: 23105906
Article Published Date : Mar 31, 2010
Authors : P K Rai, D Jaiswal, S Mehta, D K Rai, B Sharma, Geeta Watal
Study Type : Animal Study
Additional Links
Substances : Turmeric : CK(5032) : AC(2348)
Diseases : Diabetes Mellitus: Type 1 : CK(1130) : AC(301), Diabetes Mellitus: Type 2 : CK(3572) : AC(624)
Pharmacological Actions : Hepatoprotective : CK(1387) : AC(594)

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