Focused Research Topics Turmeric & Obesity

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Associated Topics included in this Focused Research

Beta-sesquiphellandrene Curcumin Curcumin: Lipidated Curcuminoids Curcumol Demethoxycurcumin Tetrahydrocurcumin Turmeric Turmeric: Fermented Turmeric: Topical Turmerin Turmerones

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33 Research Articles in Total

Both caloric restriction and dietary curcumin can improve obesity-associated comorbidities.

Pubmed Data : PLoS One. 2015 ;10(10):e0140431. Epub 2015 Oct 16. PMID: 26473740
Article Published Date : Dec 31, 2014
Authors : Marjana Rahman Sarker, Susan Franks, Nathalie Sumien, Nopporn Thangthaeng, Frank Filipetto, Michael Forster
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Obesity : CK(2443) : AC(521)
Therapeutic Actions : Dietary Modification: Caloric Restriction : CK(44) : AC(10)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630), Antioxidants : CK(8430) : AC(3132)

Curcuma longa polyphenols protect adipose cells against oxidative stress and may improve obesity-related metabolic disorders.

Pubmed Data : Biofactors. 2016 Apr 20. Epub 2016 Apr 20. PMID: 27094023
Article Published Date : Apr 19, 2016
Authors : Axelle Septembre-Malaterre, Fanny Le Sage, Sarah Hatia, Aurélie Catan, Laurent Janci, Marie-Paule Gonthier
Study Type : In Vitro Study
Additional Links
Substances : Curcuminoids : CK(4681) : AC(2355), Turmeric : CK(5583) : AC(2569)
Diseases : Obesity : CK(2443) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630), Antioxidants : CK(8430) : AC(3132)

Curcumin has a promising role as a cardioprotective agent against palmitate and high fat diet mediated cardiac dysfunction.

Pubmed Data : J Mol Cell Cardiol. 2015 Feb ;79:1-12. Epub 2014 Oct 16. PMID: 25444713
Article Published Date : Jan 31, 2015
Authors : Chunlai Zeng, Peng Zhong, Yunjie Zhao, Karvannan Kanchana, Yali Zhang, Zia A Khan, Subrata Chakrabarti, Lianpin Wu, Jingying Wang, Guang Liang
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Circulating Free Fatty Acids: Elevated : CK(3) : AC(2), High Fat Diet : CK(212) : AC(103), Obesity : CK(2443) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630), Antioxidants : CK(8430) : AC(3132), Cardioprotective : CK(1596) : AC(409), NF-kappaB Inhibitor : CK(1114) : AC(694), Nrf2 activation : CK(177) : AC(86)

Extracts of turmeric play an important role in the regulation of inflammatory reactions and oxidative stress occurring in the overweight patients.

Pubmed Data : Curr Med Chem. 2016 Nov 17. Epub 2016 Nov 17. PMID: 27855627
Article Published Date : Nov 16, 2016
Authors : Agata Jarząb, Wirginia Kukula-Koch
Study Type : Review
Additional Links
Substances : Turmeric : CK(5583) : AC(2569)
Diseases : Inflammation : CK(3240) : AC(882), Obesity : CK(2443) : AC(521), Overweight : CK(3643) : AC(612)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630), Antioxidants : CK(8430) : AC(3132)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

Review: Curcumin may have therapeutic value in obesity.

Pubmed Data : Pediatr Rehabil. 2004 Oct-Dec;7(4):245-60. PMID: 21091916
Article Published Date : Oct 01, 2004
Authors : Lini Alappat, Atif B Awad
Study Type : Review
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Obesity : CK(2443) : AC(521)
Pharmacological Actions : Antioxidants : CK(8430) : AC(3132)

Curcumin and gallic acid have a protective role in advanced glycation end products induces systemic inflammation and weight gain.

Pubmed Data : Food Chem Toxicol. 2018 Feb 9. Epub 2018 Feb 9. PMID: 29432842
Article Published Date : Feb 08, 2018
Authors : Boopathi Sowndhar Rajan, Senthamizharasi Manivasagam, Suresh Dhanusu, Navvi Chandrasekar, Kalaiselvi Krishna, Lakshmi Priya Kalaiarasu, Aadhil Ashwaq Babu, Elangovan Vellaichamy
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300), Gallic Acid : CK(58) : AC(33)
Diseases : Advanced Glycation End products (AGE) : CK(231) : AC(73), Obesity : CK(2443) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630)
Additional Keywords : Anti-Inflammatory Agents : CK(4861) : AC(1630), Anti-Inflammatory Agents : CK(4861) : AC(1630), CURCUMIN : CK(2) : AC(1), CURCUMIN : CK(2) : AC(1), CURCUMIN : CK(2) : AC(1)

Curcumin has a wide range of potential anti-obesity properties.

Pubmed Data : Eur J Nutr. 2011 Apr ;50(3):151-61. Epub 2011 Mar 27. PMID: 21442412
Article Published Date : Apr 01, 2011
Authors : Adeeb Shehzad, Taewook Ha, Fazli Subhan, Young Sup Lee
Study Type : Review
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Metabolic Syndrome X : CK(916) : AC(158), Obesity : CK(2443) : AC(521)
Pharmacological Actions : Adiponectin upregulation : CK(51) : AC(11), Anti-Inflammatory Agents : CK(4861) : AC(1630), Leptin Down-Regulation : CK(13) : AC(3)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

Oral administration of Curcuma longa associated with white pepper at doses that can be extrapolated to human exposure upon supplementation improves pro-inflammatory disorders.

Pubmed Data : PLoS One. 2013 ;8(11):e81252. Epub 2013 Nov 19. PMID: 24260564
Article Published Date : Dec 31, 2012
Authors : Audrey M Neyrinck, Maud Alligier, Patrick B Memvanga, Elodie Névraumont, Yvan Larondelle, Véronique Préat, Patrice D Cani, Nathalie M Delzenne
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300), Piperine : CK(169) : AC(84), White Pepper : CK(10) : AC(1)
Diseases : High Fat Diet : CK(212) : AC(103), Inflammation : CK(3240) : AC(882), Obesity : CK(2443) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630), NF-kappaB Inhibitor : CK(1114) : AC(694)
Additional Keywords : Dietary Concentrations : CK(95) : AC(23), Increased Bioavailability : CK(42) : AC(17), Plant Extracts : CK(7645) : AC(2539)

The findings of the present trial suggested that curcumin may exert immunomodulatory effects via altering the circulating concentrations of IL-1β, IL-4, and VEGF.

Pubmed Data : ScientificWorldJournal. 2014 ;2014:898361. Epub 2014 Feb 11. PMID: 24678280
Article Published Date : Dec 31, 2013
Authors : Shiva Ganjali, Amirhossein Sahebkar, Elahe Mahdipour, Khadijeh Jamialahmadi, Sepideh Torabi, Saeed Akhlaghi, Gordon Ferns, Seyed Mohammad Reza Parizadeh, Majid Ghayour-Mobarhan
Study Type : Human Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Obesity : CK(2443) : AC(521)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630), Immunomodulatory : CK(1287) : AC(358), Interleukin-1 beta downregulation : CK(478) : AC(205), Interleukin-4 downregulation : CK(119) : AC(34), VEGFR3 inhibition : CK(12) : AC(3)
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) : CK(1905) : AC(215)

Curcumin dose-dependently induced p27 protein accumulation and G1 arrest of synchronously replicating 3T3-L1 preadipocytes.

Pubmed Data : Biochem Biophys Rep. 2016 Mar 1 ;5:16-21. PMID: 26688832
Article Published Date : Feb 29, 2016
Authors : Bradley S Ferguson, Heesun Nam, Ron F Morrison
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Obesity : CK(2443) : AC(521)
Pharmacological Actions : Antiproliferative : CK(2546) : AC(1685)
Additional Keywords : Anti-Obesity Agents : CK(979) : AC(259)

Curcuminoid supplementation ameliorates cardiac autonomic imbalance in high-fat-fed rats, probably due to its lipid-lowering effect.

Pubmed Data : Nutrition. 2009 Jul-Aug;25(7-8):870-8. Epub 2009 Apr 23. PMID: 19398300
Article Published Date : Jul 01, 2009
Authors : Anchalee Pongchaidecha, Narissara Lailerd, Warasinee Boonprasert, Nipon Chattipakorn
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Cardiac Mortality : CK(947) : AC(86), Obesity : CK(2443) : AC(521)
Pharmacological Actions : Cardioprotective : CK(1596) : AC(409), Hypolipidemic : CK(1288) : AC(265)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

Fermented turmeric administration can be a candidate for the prevention of obesity via suppressing adipogenesis and promoting lipolysis.

Pubmed Data : Food Nutr Res. 2016 ;60:30428. Epub 2016 Jan 27. PMID: 26822962
Article Published Date : Dec 31, 2015
Authors : Ji Hye Kim, Ok-Kyung Kim, Ho-Geun Yoon, Jeongjin Park, Yanghee You, Kyungmi Kim, Yoo-Hyun Lee, Kyung-Chul Choi, Jeongmin Lee, Woojin Jun
Study Type : Animal Study
Additional Links
Substances : Turmeric: Fermented : CK(19) : AC(6)
Diseases : Obesity : CK(2443) : AC(521)
Additional Keywords : Anti-Obesity Agents : CK(979) : AC(259), Plant Extracts : CK(7645) : AC(2539)

Curcumin might significantly decrease the level of insulin resistance and leptin resistance caused by the high fat diet.

Pubmed Data : J Atheroscler Thromb. 2009;16(6):870-7. Epub 2009 Dec 22. PMID: 19176142
Article Published Date : Jan 01, 2009
Authors : Yan Yu, Sen-ke Hu, Hong Yan
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Insulin Resistance : CK(1683) : AC(346), Leptin Resistance : CK(21) : AC(9), Obesity : CK(2443) : AC(521)
Pharmacological Actions : Apoptotic : CK(2958) : AC(2075)

A bioavailable form of curcumin is well-tolerated and can positively influence weight management in overweight people.

Pubmed Data : Eur Rev Med Pharmacol Sci. 2015 Nov ;19(21):4195-202. PMID: 26592847
Article Published Date : Oct 31, 2015
Authors : F Di Pierro, A Bressan, D Ranaldi, G Rapacioli, L Giacomelli, A Bertuccioli
Study Type : Human Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Metabolic Syndrome X : CK(916) : AC(158), Obesity : CK(2443) : AC(521), Overweight : CK(3643) : AC(612)
Additional Keywords : Anti-Obesity Agents : CK(979) : AC(259)

Curcumin and resveratrol may inhibit the chronic inflammatory properties of adipose tissue.

Pubmed Data : Nutr Metab (Lond). 2008;5:17. Epub 2008 Jun 12. PMID: 18549505
Article Published Date : Jan 01, 2008
Authors : Amanda M Gonzales, Robert A Orlando
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300), Resveratrol : CK(1511) : AC(865)
Diseases : Obesity : CK(2443) : AC(521)
Pharmacological Actions : Interleukin-6 Downregulation : CK(1137) : AC(354), NF-kappaB Inhibitor : CK(1114) : AC(694), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(1823) : AC(669)

Curcumin could be a potential leading compound for development of drugs for the prevention of obesity and insulin resistance.

Pubmed Data : Toxicol Appl Pharmacol. 2016 May 18. Epub 2016 May 18. PMID: 27208389
Article Published Date : May 17, 2016
Authors : Lili Ding, Jinmei Li, Baoliang Song, Xu Xiao, Binfeng Zhang, Meng Qi, Wendong Huang, Li Yang, Zhengtao Wang
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : High Fat Diet : CK(212) : AC(103), Insulin Resistance : CK(1683) : AC(346), Obesity : CK(2443) : AC(521)
Pharmacological Actions : Hypolipidemic : CK(1288) : AC(265)
Additional Keywords : Anti-Obesity Agents : CK(979) : AC(259), Gene Expression Regulation : CK(431) : AC(214)

Curcumin exhibits anti-obesity properties in vitro.

Pubmed Data : Mol Cell Biochem. 2011 Jan 9. Epub 2011 Jan 9. PMID: 21221723
Article Published Date : Jan 09, 2011
Authors : Jiong Zhao, Xue-Bing Sun, Fei Ye, Wei-Xi Tian
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Obesity : CK(2443) : AC(521)

Curcumin inhibits leptin-induced hepatic stellate cell activation.

Pubmed Data : Br J Pharmacol. 2010 Nov;161(5):1137-49. PMID: 20977462
Article Published Date : Nov 01, 2010
Authors : Youcai Tang, Anping Chen
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Hepatic Steatosis : CK(131) : AC(35), Leptin: Elevated Levels : CK(24) : AC(12), Liver Fibrosis : CK(246) : AC(104), Liver Steatosis : CK(25) : AC(4), Obesity : CK(2443) : AC(521)

Curcumin is able to alleviate the harmful reaction of leptin on podocytes and reduce the severity of obesity-related glomerulopathy.

Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:827472. Epub 2015 Oct 11. PMID: 26539236
Article Published Date : Dec 31, 2014
Authors : Bao-Li Liu, Yi-Pu Chen, Hong Cheng, Yan-Yan Wang, Hong-Liang Rui, Min Yang, Hong-Rui Dong, Dan-Nuo Han, Jing Dong
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Glomerulosclerosis : CK(8) : AC(5), Leptin: Elevated Levels : CK(24) : AC(12), Obesity : CK(2443) : AC(521)
Pharmacological Actions : Renoprotective : CK(572) : AC(254), Wnt/β-catenin pathway down-regulation : CK(49) : AC(27)

Curcumin may have anti-obesity properties.

Pubmed Data : J Nutr Biochem. 2010 Dec 27. Epub 2010 Dec 27. PMID: 21189228
Article Published Date : Dec 27, 2010
Authors : Choon Young Kim, Thuc T Le, Chihyu Chen, Ji-Xin Cheng, Kee-Hong Kim
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Obesity : CK(2443) : AC(521), Weight Problems : CK(3137) : AC(520)

Curcumin plays a dual modulatory role in inhibition of adipogenesis as well as induction of the brown fat-like phenotype.

Pubmed Data : J Nutr Biochem. 2016 Jan ;27:193-202. Epub 2015 Sep 21. PMID: 26456563
Article Published Date : Dec 31, 2015
Authors : Jameel Lone, Jae Heon Choi, Sang Woo Kim, Jong Won Yun
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Obesity : CK(2443) : AC(521)
Additional Keywords : Anti-Obesity Agents : CK(979) : AC(259)

Curcumin protected against the development of hepatic steatosis by reducing hepatic fat accumulation.

Pubmed Data : Basic Clin Pharmacol Toxicol. 2013 Sep ;113(3):152-7. Epub 2013 May 25. PMID: 23574662
Article Published Date : Aug 31, 2013
Authors : Min Young Um, Kwang Hyun Hwang, Jiyun Ahn, Tae Youl Ha
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Fatty Liver : CK(887) : AC(204), Hepatic Steatosis : CK(131) : AC(35), High Fat Diet : CK(212) : AC(103), Obesity : CK(2443) : AC(521)
Pharmacological Actions : Hepatoprotective : CK(2523) : AC(1099), Hypolipidemic : CK(1288) : AC(265)

Curcumin-induced suppression of adipogenic differentiation, indicating its therapeutic role in obesity.

Pubmed Data : Am J Physiol Cell Physiol. 2010 Jun;298(6):C1510-6. Epub 2010 Mar 31. PMID: 20357182
Article Published Date : Jun 01, 2010
Authors : Jiyun Ahn, Hyunjung Lee, Suna Kim, Taeyoul Ha
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Obesity : CK(2443) : AC(521)
Pharmacological Actions : Anti-Adipogenic : CK(110) : AC(52)
Additional Keywords : Anti-Obesity Agents : CK(979) : AC(259)

Korean turmeric may contribute to the decreasing of body fat and regulating leptin secretion.

Pubmed Data : Nutr Res Pract. 2016 Oct ;10(5):487-493. Epub 2016 Aug 29. PMID: 27698955
Article Published Date : Sep 30, 2016
Authors : Won-Yeong Song, Jeong-Hwa Choi
Study Type : Animal Study
Additional Links
Substances : Turmeric : CK(5583) : AC(2569)
Diseases : High Fat Diet : CK(212) : AC(103), Obesity : CK(2443) : AC(521)
Pharmacological Actions : Leptin Down-Regulation : CK(13) : AC(3)
Additional Keywords : Anti-Obesity Agents : CK(979) : AC(259)

These findings suggest the reduction of carbohydrate absorption during the gastrointestinal passage after turmeric powder and spent turmeric powder treatment.

Pubmed Data : Food Funct. 2015 Nov 19. Epub 2015 Nov 19. PMID: 26583652
Article Published Date : Nov 18, 2015
Authors : Kyu-Ho Han, Chang-Hyun Lee, Mikio Kinoshita, Chan-Ho Oh, Ken-Ichiro Shimada, Michihiro Fukushima
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Turmeric : CK(5583) : AC(2569)
Diseases : High Fat Diet : CK(212) : AC(103), Obesity : CK(2443) : AC(521)
Additional Keywords : Anti-Obesity Agents : CK(979) : AC(259)

Attenuation by tetrahydrocurcumin of adiposity and hepatic steatosis in mice with high-fat-diet-induced obesity.

Pubmed Data : J Agric Food Chem. 2018 Nov 16. Epub 2018 Nov 16. PMID: 30415544
Article Published Date : Nov 15, 2018
Authors : Min-Hsiung Pan, Jin-Wun Chen, Zwe-Ling Kong, Jia-Ching Wu, Chi-Tang Ho, Ching-Shu Lai
Study Type : Animal Study
Additional Links
Substances : Tetrahydrocurcumin : CK(80) : AC(39)
Diseases : Hepatic Steatosis : CK(131) : AC(35), Nonalcoholic fatty liver disease (NAFLD) : CK(789) : AC(183), Obesity : CK(2443) : AC(521)
Pharmacological Actions : Hepatoprotective : CK(2523) : AC(1099)

A fermented turmeric extract exhibits anti-obesity properties.

Pubmed Data : J Sci Food Agric. 2012 Jan 25. Epub 2012 Jan 25. PMID: 22278718
Article Published Date : Jan 25, 2012
Authors : Jin-Nyoung Ho, Ja Young Jang, Ho-Geun Yoon, Yongjae Kim, Sunoh Kim, Woojin Jun, Jeongmin Lee
Study Type : Animal Study
Additional Links
Substances : Turmeric: Fermented : CK(19) : AC(6)
Diseases : High Cholesterol : CK(1774) : AC(271), Obesity : CK(2443) : AC(521), Triglycerides: Elevated : CK(718) : AC(117)
Pharmacological Actions : Anti-Adipogenic : CK(110) : AC(52), Hypolipidemic : CK(1288) : AC(265), Lipolytic : CK(45) : AC(16)

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