Focused Research Topics Diabetes Mellitus: Type 2 & Curcumin

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Associated Topics included in this Focused Research

Diabetes Mellitus: Type 2

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50 Research Articles in Total

Antidiabetic Properties of Curcumin I: Evidence from In Vitro Studies.

Pubmed Data : Nutrients. 2020 Jan 1 ;12(1). Epub 2020 Jan 1. PMID: 31906278
Article Published Date : Dec 31, 2019
Authors : Danja J Den Hartogh, Alessandra Gabriel, Evangelia Tsiani
Study Type : Review
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14906), Antioxidants : CK(32218) : AC(13940), Hepatoprotective : CK(8320) : AC(3708), Hypoglycemic Agents : CK(8194) : AC(1991), Immunomodulatory : CK(5935) : AC(2267), Renoprotective : CK(4133) : AC(1899)

Curcumin possesses anti-diabetic effects and mitigates diabetes complications

Pubmed Data : Curr Top Med Chem. 2015 Jun 19. Epub 2015 Jun 19. PMID: 26088351
Article Published Date : Jun 18, 2015
Authors : Seyed Fazel Nabavi, Raman Thiagarajan, Luca Rastrelli, Maria Daglia, Eduardo Sobarzo-Sanchez, Heshmatollah Alinezhad, Seyed Mohammad Nabavi
Study Type : Review
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Diabetic Complications : CK(4283) : AC(1510)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14906), Antioxidants : CK(32218) : AC(13940)
Additional Keywords : Advanced Glycation End Products : CK(11) : AC(2)

Effects of turmeric and its constituent curcumin on the metabolic syndrome.

Pubmed Data : J Integr Med. 2022 05 ;20(3):193-203. Epub 2022 Mar 1. PMID: 35292209
Article Published Date : Dec 31, 2021
Authors : Zeinab Vafaeipour, Bibi Marjan Razavi, Hossein Hosseinzadeh
Study Type : Review
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14906), Antihypertensive Agents : CK(6871) : AC(989), Antioxidants : CK(32218) : AC(13940), Hypolipidemic : CK(8317) : AC(1969)
Additional Keywords : Plant Extracts : CK(18030) : AC(6686)

Molecular mechanisms underlying curcumin-mediated therapeutic effects in type 2 diabetes and cancer.

Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:9698258. Epub 2018 Mar 20. PMID: 29743988
Article Published Date : Dec 31, 2017
Authors : Marzena Wojcik, Michal Krawczyk, Pawel Wojcik, Katarzyna Cypryk, Lucyna Alicja Wozniak
Study Type : Review
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Cancers: All : CK(34182) : AC(13930), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14906), Antioxidants : CK(32218) : AC(13940), Antiproliferative : CK(9389) : AC(7261), Chemopreventive : CK(6381) : AC(2130), Hypoglycemic Agents : CK(8194) : AC(1991)

The effects of curcumin on diabetes mellitus: a systematic review.

Pubmed Data : Front Endocrinol (Lausanne). 2021 ;12:669448. Epub 2021 May 3. PMID: 34012421
Article Published Date : Dec 31, 2020
Authors : Ledyane Taynara Marton, Laís Maria Pescinini-E-Salzedas, Maria Eduarda Côrtes Camargo, Sandra M Barbalho, Jesselina F Dos Santos Haber, Renata Vargas Sinatora, Claudia Rucco Penteado Detregiachi, Raul J S Girio, Daniela Vieira Buchaim, Patricia Cincotto Dos Santos Bueno
Study Type : Review
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 1 : CK(1952) : AC(582), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14906), Anticholesteremic Agents : CK(4029) : AC(658), Antioxidants : CK(32218) : AC(13940)

A combined dosage of tetrahydrocurcumin and chlorogenic acid protects against experimentally induced type 2 diabetes in rats.

Pubmed Data : Mol Cell Biochem. 2010 Aug;341(1-2):109-17. Epub 2010 Mar 26. PMID: 20339905
Article Published Date : Aug 01, 2010
Authors : Leelavinothan Pari, Krishnamoorthy Karthikesan, Venugopal P Menon
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid : CK(431) : AC(189), Curcumin : CK(6902) : AC(3208), Tetrahydrocurcumin : CK(142) : AC(80)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Oxidative Stress : CK(13443) : AC(5345)
Pharmacological Actions : Antioxidants : CK(32218) : AC(13940)

Curcumin is a potential glucose-lowering agent and antioxidant in type 2 diabetic mice.

Pubmed Data : Phytother Res. 2008 Feb;22(2):180-4. PMID: 18398869
Article Published Date : Feb 01, 2008
Authors : Kwon-Il Seo, Myung-Sook Choi, Un Ju Jung, Hye-Jin Kim, Jiyoung Yeo, Seon-Min Jeon, Mi-Kyung Lee
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Insulin Resistance : CK(4532) : AC(1064)
Pharmacological Actions : Antioxidants : CK(32218) : AC(13940), Hypoglycemic Agents : CK(8194) : AC(1991)

Curcumin supplementation could ameliorate cognitive deficits and reverse biochemical alterations in a ICV-streptozotocin Alzheimer's rat model.

Pubmed Data : Eur J Pharmacol. 2016 Jan 5 ;770:52-60. Epub 2015 Dec 2. PMID: 26638997
Article Published Date : Jan 04, 2016
Authors : Doaa M Samy, Cherine A Ismail, Rasha A Nassra, Teshreen M Zeitoun, Azhar M Nomair
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Alzheimer's Disease : CK(4948) : AC(2113), Brain: Oxidative Stress : CK(635) : AC(344), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Antioxidants : CK(32218) : AC(13940), Neuroprotective Agents : CK(17667) : AC(7482)

Curcumin works synergistically with insulin on muscle cell glucose metabolism.

Pubmed Data : Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2366-73. Epub 2010 Jun 1. PMID: 20561944
Article Published Date : Aug 01, 2010
Authors : Changkeun Kang, Euikyung Kim
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Insipidus : CK(45) : AC(6), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Insulin Resistance : CK(4532) : AC(1064)
Pharmacological Actions : Antioxidants : CK(32218) : AC(13940), Hypoglycemic Agents : CK(8194) : AC(1991)
Additional Keywords : Drug Synergy : CK(389) : AC(174)

Effects of curcumin, a bioactive component of turmeric, on type 2 diabetes mellitus and its complications.

Pubmed Data : Food Funct. 2022 Nov 28 ;13(23):11999-12010. Epub 2022 Nov 28. PMID: 36367124
Article Published Date : Nov 27, 2022
Authors : Osman Bozkurt, Betül Kocaadam-Bozkurt, Hilal Yildiran
Study Type : Review
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Inflammation : CK(15162) : AC(5110)
Pharmacological Actions : Antioxidants : CK(32218) : AC(13940), Hypoglycemic Agents : CK(8194) : AC(1991), Hypolipidemic : CK(8317) : AC(1969)

Compounds within turmeric suppress an increase in blood glucose levels in type 2 diabetic mice.

Pubmed Data : J Agric Food Chem. 2005 Feb 23;53(4):959-63. PMID: 15713005
Article Published Date : Feb 23, 2005
Authors : Tozo Nishiyama, Tatsumasa Mae, Hideyuki Kishida, Misuzu Tsukagawa, Yoshihiro Mimaki, Minpei Kuroda, Yutaka Sashida, Kazuma Takahashi, Teruo Kawada, Kaku Nakagawa, Mikio Kitahara
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Alcohol Toxicity : CK(1191) : AC(473), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Hypoglycemic Agents : CK(8194) : AC(1991)
Additional Keywords : Plant Extracts : CK(18030) : AC(6686)

Curcumin extract for prevention of type 2 diabetes.

Pubmed Data : Diabetes Care. 2012 Nov ;35(11):2121-7. Epub 2012 Jul 6. PMID: 22773702
Article Published Date : Oct 31, 2012
Authors : Somlak Chuengsamarn, Suthee Rattanamongkolgul, Rataya Luechapudiporn, Chada Phisalaphong, Siwanon Jirawatnotai
Study Type : Human In Vitro
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Insulin Resistance : CK(4532) : AC(1064), Prediabetes : CK(991) : AC(126)
Additional Keywords : Beta Cell Protection : CK(61) : AC(25), Plant Extracts : CK(18030) : AC(6686)

Dietary supplementation with curcumin reduce circulating levels of glycogen synthase kinase-3β and islet amyloid polypeptide,

Pubmed Data : Nutrients. 2020 Apr 9 ;12(4). Epub 2020 Apr 9. PMID: 32283762
Article Published Date : Apr 08, 2020
Authors : Rohith N Thota, Jessica I Rosato, Cintia B Dias, Tracy L Burrows, Ralph N Martins, Manohar L Garg
Study Type : Human Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Alzheimer's Disease : CK(4948) : AC(2113), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Neuroprotective Agents : CK(17667) : AC(7482)
Additional Keywords : Risk Reduction : CK(17834) : AC(1988)

Quercetin, epigallocatechin gallate, curcumin, and resveratrol: from dietary sources to human microRNA modulation.

Pubmed Data : Molecules. 2019 Dec 23 ;25(1). Epub 2019 Dec 23. PMID: 31878082
Article Published Date : Dec 22, 2019
Authors : Erika Cione, Chiara La Torre, Roberto Cannataro, Maria Cristina Caroleo, Pierluigi Plastina, Luca Gallelli
Study Type : Review
Additional Links
Substances : Curcumin : CK(6902) : AC(3208), EGCG (Epigallocatechin gallate) : CK(1503) : AC(808), Quercetin : CK(1856) : AC(841), Resveratrol : CK(3081) : AC(1497)
Diseases : Cardiovascular Diseases : CK(16891) : AC(2776), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : MicroRNA modulator : CK(1525) : AC(889)
Additional Keywords : Epigenetic Modification : CK(532) : AC(202)

Tetrahydrocurcumin displays antihyperlipidaemic effect in addition to its antidiabetic effect in type 2 diabetic rats.

Pubmed Data : Basic Clin Pharmacol Toxicol. 2006 Aug;99(2):122-7. PMID: 16918712
Article Published Date : Aug 01, 2006
Authors : Pidaran Murugan, Leelavinothan Pari
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208), Tetrahydrocurcumin : CK(142) : AC(80)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Oxidative Stress : CK(13443) : AC(5345)
Pharmacological Actions : Hypolipidemic : CK(8317) : AC(1969)

Dietary curcumin restores insulin homeostasis in diet-induced obese aged mice.

Pubmed Data : Aging (Albany NY). 2022 01 11 ;14(1):225-239. Epub 2022 Jan 11. PMID: 35017319
Article Published Date : Jan 10, 2022
Authors : Su-Jeong Lee, Prabha Chandrasekran, Caio Henrique Mazucanti, Jennifer F O'Connell, Josephine M Egan, Yoo Kim
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Aging : CK(5699) : AC(1372), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Obesity : CK(9664) : AC(2524)
Additional Keywords : Anti-Obesity Agents : CK(4281) : AC(1220)

Zingiber officinale, Phyllanthus emblica, Cinnamomum verum, and Curcuma longa to prevent type 2 diabetes.

Pubmed Data : Curr Diabetes Rev. 2022 Nov 24. Epub 2022 Nov 24. PMID: 36424773
Article Published Date : Nov 23, 2022
Authors : Uththara Subodhini Wijewardhana, Madhura Arunoda Jayasinghe, Isuru Wijesekara, K K D S Ranaweera
Study Type : Review
Additional Links
Substances : Amla Fruit : CK(265) : AC(94), Cinnamon : CK(691) : AC(201), Curcumin : CK(6902) : AC(3208), Ginger : CK(1589) : AC(476), Turmeric : CK(8993) : AC(3754)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Hypoglycemic Agents : CK(8194) : AC(1991)

Noble heart failure therapy using food compositions.

Pubmed Data : Yakugaku Zasshi. 2018 ;138(10):1263-1269. PMID: 30270270
Article Published Date : Dec 31, 2017
Authors : Tatsuya Morimoto, Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Koji Hasegawa
Study Type : Review
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Heart Failure : CK(1847) : AC(316)
Pharmacological Actions : Cardioprotective : CK(8685) : AC(2807)
Additional Keywords : Phytotherapy : CK(3908) : AC(1012)

The effect of curcumin phytosome on the treatment of patients with non-alcoholic fatty liver disease.

Pubmed Data : Adv Exp Med Biol. 2021 ;1308:25-35. PMID: 33861434
Article Published Date : Dec 31, 2020
Authors : Seyed Reza Mirhafez, Mohsen Azimi-Nezhad, Maryam Dehabeh, Mitra Hariri, Ronika Danesh Naderan, Ali Movahedi, Mohammed Abdalla, Thozhukat Sathyapalan, Amirhossein Sahebkar
Study Type : Human Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Nonalcoholic fatty liver disease (NAFLD) : CK(3352) : AC(939)
Pharmacological Actions : Hepatoprotective : CK(8320) : AC(3708)

Curcumin and tetrahydrocurcumin have antihyperlipidemic properties in experimental type 2 diabetic rats.

Pubmed Data : JPEN J Parenter Enteral Nutr. 1986 Sep-Oct;10(5):530-2. PMID: 17994458
Article Published Date : Sep 01, 1986
Authors : Leelavinothan Pari, Pidaran Murugan
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes: Cardiovascular Illness : CK(741) : AC(131), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Hypolipidemic : CK(8317) : AC(1969)

Potential therapeutic effects of curcumin on glycemic and lipid profile in uncomplicated type 2 diabetes.

Pubmed Data : Nutrients. 2021 Jan 27 ;13(2). Epub 2021 Jan 27. PMID: 33514002
Article Published Date : Jan 26, 2021
Authors : Emma Altobelli, Paolo Matteo Angeletti, Ciro Marziliano, Marianna Mastrodomenico, Anna Rita Giuliani, Reimondo Petrocelli
Study Type : Meta Analysis
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Hypoglycemic Agents : CK(8194) : AC(1991), Hypolipidemic : CK(8317) : AC(1969)

Effect of Curcuma longa on glycemia, neuropathic sensation and advanced glycation end product in diabetic patients.

Pubmed Data : Pak J Pharm Sci. 2022 May ;35(3(Special)):873-878. PMID: 35791581
Article Published Date : Apr 30, 2022
Authors : Waseem Abbas, Rafeeq Alam Khan, Mirza Tasawar Baig, Safder Ali Shaikh
Study Type : Human Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Advanced Glycation End products (AGE) : CK(579) : AC(242), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Anti-Glycation Agents : CK(331) : AC(160), Hypoglycemic Agents : CK(8194) : AC(1991)

Tetrahydrocurcumin normalizes blood glucose and causes a marked improvement of altered carbohydrate metabolic enzymes in diabetic animals.

Pubmed Data : J Basic Clin Physiol Pharmacol. 2005;16(4):257-74. PMID: 16438392
Article Published Date : Jan 01, 2005
Authors : Leelavinothan Pari, Pidaran Murugan
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208), Tetrahydrocurcumin : CK(142) : AC(80)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Hypoglycemic Agents : CK(8194) : AC(1991)

The results shows that astragalosides and curcumin could lower the abnormal blood glucose levels and GSP levels.

Pubmed Data : Saudi Pharm J. 2017 May ;25(4):477-481. Epub 2017 Apr 28. PMID: 28579878
Article Published Date : Apr 30, 2017
Authors : Mingsan Miao, Jing Liu, Tan Wang, Xue Liang, Ming Bai
Study Type : Animal Study
Additional Links
Substances : Astragaloside : CK(796) : AC(453), Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Hypoglycemic Agents : CK(8194) : AC(1991)

Treatment with combinatorial extract of curcumin presented a significantly better therapeutic potential when compared with curcumin alone.

Pubmed Data : J Complement Integr Med. 2016 Jun 25. Epub 2016 Jun 25. PMID: 27343476
Article Published Date : Jun 24, 2016
Authors : Ginpreet Kaur, Mihir Invally, Meena Chintamaneni
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208), Piperine : CK(578) : AC(254), Quercetin : CK(1856) : AC(841)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Hypoglycemic Agents : CK(8194) : AC(1991)
Additional Keywords : Natural Substance Synergy : CK(1339) : AC(654), Natural Substances Versus Drugs : CK(2768) : AC(555)

Turmeric extracts demonstrated an antidiabetic effect in streptozotocin-nicotinamide induced type 2 diabetes.

Pubmed Data : J Ayurveda Integr Med. 2021 Jul-Sep;12(3):474-479. Epub 2021 Aug 2. PMID: 34353691
Article Published Date : Jun 30, 2021
Authors : Vinay Kumar Sayeli, Ashok K Shenoy
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Hypoglycemic Agents : CK(8194) : AC(1991), Insulin Sensitizers : CK(1721) : AC(399)
Additional Keywords : Natural Substances Versus Drugs : CK(2768) : AC(555)

Zinc and curcumin supplementation exerted a beneficial effect on several key glycemic parameters.

Pubmed Data : Phytother Res. 2021 Apr 23. Epub 2021 Apr 23. PMID: 33893671
Article Published Date : Apr 22, 2021
Authors : Majid Karandish, Hassan Mozaffari-Khosravi, Seyed Mohammad Mohammadi, Bahman Cheraghian, Maryam Azhdari
Study Type : Human Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208), Zinc : CK(1953) : AC(342)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Hypoglycemic Agents : CK(8194) : AC(1991)

Abnormal electrophysiological characteristics of VGSCs can be ameliorated efficaciously by a period of treatment with curcumin.

Pubmed Data : Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 Nov ;31(6):541-8. PMID: 27215022
Article Published Date : Oct 31, 2015
Authors : Bo Meng, Lu-lu Shen, Xiao-ting Shi, Yong-sheng Gong, Xiao-fang Fan, Jun Li, Hong Cao
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Neuropathic Pain : CK(841) : AC(285)

Curcumin as a major active component of turmeric attenuates proteinuria in patients with overt diabetic nephropathy.

Pubmed Data : J Res Med Sci. 2019 ;24:77. Epub 2019 Aug 28. PMID: 31523263
Article Published Date : Dec 31, 2018
Authors : Azam Vanaie, Shahrzad Shahidi, Bijan Iraj, Zahra Dana Siadat, Mansure Kabirzade, Feloria Shakiba, Mohsen Mohammadi, Homeira Parvizian
Study Type : Human Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Diabetic Nephropathy : CK(1356) : AC(518), Proteinuria : CK(177) : AC(33)

Curcumin has been demonstrated to effectively prevent or ameliorate diabetic mellitus and its complications including diabetic neuropathic pain.

Pubmed Data : Neurosci Lett. 2015 Aug 14. Epub 2015 Aug 14. PMID: 26282904
Article Published Date : Aug 13, 2015
Authors : Bo Meng, Lu-Lu Shen, Xiao-Ting Shi, Yong-Sheng Gong, Xiao-Fang Fan, Jun Li, Hong Cao
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Diabetic Neuropathy : CK(377) : AC(97), Neuropathic Pain : CK(841) : AC(285)
Pharmacological Actions : Analgesics : CK(5835) : AC(998)

Curcumin may prove useful for patients with diabetes by improving both β-cell function and relieving insulin resistance.

Pubmed Data : Nutr Diabetes. 2016 ;6:e205. Epub 2016 Apr 25. PMID: 27110686
Article Published Date : Dec 31, 2015
Authors : S Weisberg, R Leibel, D V Tortoriello
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Insulin Resistance : CK(4532) : AC(1064)
Pharmacological Actions : Insulin Sensitizers : CK(1721) : AC(399), Proteasome Inhibitors : CK(59) : AC(40)

Curcumin significantly downregulated the plasma membrane redox system activity in a dose-dependent manner.

Pubmed Data : Biochem Res Int. 2016;2016:6025245. Epub 2016 Jan 19. PMID: 26904287
Article Published Date : Dec 31, 2015
Authors : Prabhakar Singh, Rajesh Kumar Kesharwani, Krishna Misra, Syed Ibrahim Rizvi
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Redox Modulator : CK(9) : AC(5)
Additional Keywords : Dose Response : CK(1769) : AC(699)

Curcumin's blood sugar lowering effect may be due to its inhibitory effect on hepatic gluconeogenesis.

Pubmed Data : Biochem Biophys Res Commun. 2009 Oct 16;388(2):377-82. Epub 2009 Aug 8. PMID: 19665995
Article Published Date : Oct 16, 2009
Authors : Teayoun Kim, Jessica Davis, Albert J Zhang, Xiaoming He, Suresh T Mathews
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes Mellitus: Type 1 : CK(1952) : AC(582), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : AMP-activated protein kinase modulation : CK(6) : AC(4), Gluconeogenesis Inhibitor : CK(21) : AC(15)
Additional Keywords : Metformin Alternatives : CK(19) : AC(6), Natural Substances Versus Drugs : CK(2768) : AC(555)

Curcuminoids plus piperine modulate adipokines in type 2 diabetes mellitus.

Pubmed Data : Curr Clin Pharmacol. 2018 Jan 3. Epub 2018 Jan 3. PMID: 29299989
Article Published Date : Jan 02, 2018
Authors : Amirhossein Sahebkar, Yunes Panahi, Nahid Khalili, Ebrahim Sahebi, Soha Namazi, Stephen L Atkin, Muhammed Majeed
Study Type : Human Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208), Piperine : CK(578) : AC(254)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)
Pharmacological Actions : Adiponectin upregulation : CK(229) : AC(41)

Tetrahydrocurcumin increases the number of total cellular insulin binding sites resulting in a significant increase in plasma insulin.

Pubmed Data : J Biosci. 2008 Mar;33(1):63-72. PMID: 18376071
Article Published Date : Mar 01, 2008
Authors : Pidaran Murugan, Leelavinothan Pari, Chippada Appa Rao
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208), Tetrahydrocurcumin : CK(142) : AC(80)
Diseases : Diabetes Mellitus: Type 2 : CK(11728) : AC(2449), Insulin Resistance : CK(4532) : AC(1064)

Turmeric and curcumin have anti-diabetic actions.

Pubmed Data : Plant Foods Hum Nutr. 2002;57(1):41-52. PMID: 11855620
Article Published Date : Jan 01, 2002
Authors : N Arun, N Nalini
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(6902) : AC(3208)
Diseases : Diabetes: Glycation/A1C : CK(210) : AC(33), Diabetes Mellitus: Type 1 : CK(1952) : AC(582), Diabetes Mellitus: Type 2 : CK(11728) : AC(2449)

This document is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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