Focused Research Topics Parkinson's Disease & Exercise

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Associated Topics included in this Focused Research

Parkinson's Disease

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View the Evidence
19 Research Articles in Total

Exercise attenuates mitochondrial autophagy and neuronal degeneration in MPTP induced Parkinson's disease.

Pubmed Data : Folia Neuropathol. 2024 Jan 4. Epub 2024 Jan 4. PMID: 38174683
Article Published Date : Jan 03, 2024
Authors : Zhiwei Li, Hua Lv, Xiaoli Cui, Wei Di, Xiansong Cheng, Jun Liu, Alok Tripathi
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14362), Antioxidants : CK(32218) : AC(13553), Neuroprotective Agents : CK(17667) : AC(7179)

Physical exercise inhibits inflammation and microglial activation.

Pubmed Data : Cells. 2019 Jul 9 ;8(7). Epub 2019 Jul 9. PMID: 31324021
Article Published Date : Jul 08, 2019
Authors : Onanong Mee-Inta, Zi-Wei Zhao, Yu-Min Kuo
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease : CK(4948) : AC(2032), Brain: Microglial Activation : CK(164) : AC(111), Brain Inflammation : CK(1650) : AC(860), Inflammation : CK(14780) : AC(4972), Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14362)

Treadmill exercise alleviates neuronal damage by suppressing NLRP3 inflammasome and microglial activation.

Pubmed Data : Brain Res Bull. 2021 Jul 2. Epub 2021 Jul 2. PMID: 34224819
Article Published Date : Jul 01, 2021
Authors : Wei Wang, Ziyan Lv, Jin Gao, Mengting Liu, Yuxin Wang, Chuanxi Tang, Jie Xiang
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation : CK(1650) : AC(860), Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Anti-Inflammatory Agents : CK(35225) : AC(14362), Neuroprotective Agents : CK(17667) : AC(7179)

Several trials with elderly individuals and patients with neurodegenerative diseases report exercise induced cognitive improvements.

Pubmed Data : Expert Rev Neurother. 2016 May 6:1-12. Epub 2016 May 6. PMID: 27086703
Article Published Date : May 05, 2016
Authors : Carlos Campos, Nuno Barbosa F Rocha, Eduardo Lattari, Flávia Paes, António E Nardi, Sérgio Machado
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease : CK(4948) : AC(2032), Neurodegenerative Diseases : CK(12159) : AC(3958), Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Additional Keywords : Risk Reduction : CK(17786) : AC(1980)

Daily physical activity has beneficial effects on behaviour and cognitive function among adults with Parkinson's disease.

Pubmed Data : Disabil Health J. 2017 Jun 1. Epub 2017 Jun 1. PMID: 28596093
Article Published Date : May 31, 2017
Authors : Paul D Loprinzi, Megan M Danzl, Elizabeth Ulanowski, Calli Paydo
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Neuroprotective Agents : CK(17667) : AC(7179)

Long-term voluntary physical exercise exerts neuroprotective effects and motor disturbance alleviation in a rat model of Parkinson's disease.

Pubmed Data : Behav Neurol. 2019 ;2019:4829572. Epub 2019 Dec 5. PMID: 31885725
Article Published Date : Dec 31, 2018
Authors : Wan-Ling Tsai, Hsin-Yung Chen, Ying-Zu Huang, Yuan-Hao Chen, Chi-Wei Kuo, Kai-Yun Chen, Tsung-Hsun Hsieh
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Neuroprotective Agents : CK(17667) : AC(7179)

Physical activity has a positive impact on the prevention and treatment of Parkinson's disease.

Pubmed Data : Oxid Med Cell Longev. 2020 ;2020:4293071. Epub 2020 Feb 13. PMID: 32215173
Article Published Date : Dec 31, 2019
Authors : Baozhu Fan, Riffat Jabeen, Bing Bo, Chunlei Guo, Mengjie Han, Hui Zhang, Juan Cen, Xinying Ji, Jianshe Wei
Study Type : Review
Additional Links
Diseases : Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Neuroprotective Agents : CK(17667) : AC(7179)
Additional Keywords : Physical Activity : CK(518) : AC(58)

The aquatic exercise program induced functional improvement in individuals with Parkinson's disease.

Pubmed Data : Physiol Behav. 2020 Aug 14 ;227:113135. Epub 2020 Aug 14. PMID: 32798568
Article Published Date : Aug 13, 2020
Authors : Grazielle Silva De Oliveira, Lucio Iraci, Gislaine Siqueira Pinheiro, Marcela Zimmermann Casal, Aline Nogueira Haas, Daniela Pochmann, Flavia Gomes Martinez, Viviane Elsner, Caroline Dani
Study Type : Human Study
Additional Links
Substances : Grape : CK(6309) : AC(1803)
Diseases : Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Brain-derived neurotrophic factor modulator : CK(676) : AC(256), Neuroprotective Agents : CK(17667) : AC(7179)
Additional Keywords : Epigenetic Modification : CK(520) : AC(202)

The benefits and mechanisms of exercise training for Parkinson's disease.

Pubmed Data : Life Sci. 2020 Jan 22 ;245:117345. Epub 2020 Jan 22. PMID: 31981631
Article Published Date : Jan 21, 2020
Authors : Ya-Shuo Feng, Si-Dong Yang, Zi-Xuan Tan, Man-Man Wang, Ying Xing, Fang Dong, Feng Zhang
Study Type : Review
Additional Links
Diseases : Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Neuroprotective Agents : CK(17667) : AC(7179)

The combination of carvacrol and exercise could be an effective therapeutic tool for treatment of neurobehavioral deficits in Parkinson's disease patients.

Pubmed Data : Arq Neuropsiquiatr. 2019 Jul 29 ;77(7):493-500. Epub 2019 Jul 29. PMID: 31365641
Article Published Date : Jul 28, 2019
Authors : Leila Hamzehloei, Mohammad Ebrahim Rezvani, Ziba Rajaei
Study Type : Human Study
Additional Links
Substances : Carvacrol : CK(300) : AC(172)
Diseases : Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Neuroprotective Agents : CK(17667) : AC(7179)

The effect of preventive exercise on the neuroprotection in 6-hydroxydopamine-lesioned rat brain.

Pubmed Data : Appl Physiol Nutr Metab. 2019 Dec ;44(12):1267-1275. Epub 2019 Nov 6. PMID: 31691583
Article Published Date : Nov 30, 2019
Authors : Zeinab Rezaee, Sayed Mohammad Marandi, Hojjatallah Alaei, Fahimeh Esfarjani
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Neuroprotective Agents : CK(17667) : AC(7179)

The role of exercise in Parkinson's disease.

Pubmed Data : J Geriatr Psychiatry Neurol. 2021 Jul ;34(4):321-330. PMID: 34219524
Article Published Date : Jun 30, 2021
Authors : Mallory Emig, Tikku George, Justin K Zhang, Momina Soudagar-Turkey
Study Type : Review
Additional Links
Diseases : Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Neuroprotective Agents : CK(17667) : AC(7179)

This study suggested that exercises as inexpensive, non-invasive and easy-to-implement strategies could be applied for Parkinson's disease patients.

Pubmed Data : Tremor Other Hyperkinet Mov (N Y). 2021 Apr 27 ;11:15. Epub 2021 Apr 27. PMID: 33981478
Article Published Date : Apr 26, 2021
Authors : Sajjad Farashi, Leila Kiani, Saeid Bashirian
Study Type : Human Study
Additional Links
Diseases : Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Neuroprotective Agents : CK(17667) : AC(7179)

Treadmill exercise could effectively alleviate cognitive disorders.

Pubmed Data : Int J Mol Sci. 2023 Apr 25 ;24(9). Epub 2023 Apr 25. PMID: 37175535
Article Published Date : Apr 24, 2023
Authors : Chuanxi Tang, Mengting Liu, Zihang Zhou, Hao Li, Chenglin Yang, Li Yang, Jie Xiang
Study Type : Animal Study
Additional Links
Diseases : Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Pharmacological Actions : Brain-derived neurotrophic factor modulator : CK(676) : AC(256), Neuroprotective Agents : CK(17667) : AC(7179)

Effects of exercise on long-term potentiation in neuropsychiatric disorders.

Pubmed Data : Adv Exp Med Biol. 2020 ;1228:439-451. PMID: 32342476
Article Published Date : Dec 31, 2019
Authors : Paul D Loprinzi
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease : CK(4948) : AC(2032), Parkinson's Disease : CK(2808) : AC(1032)
Therapeutic Actions : Exercise : CK(6247) : AC(935)

This review highlights current evidence supporting the disease-altering potential of PA and exercise through modifications of neuroimmune responses.

Pubmed Data : Brain Res Bull. 2016 Mar 26 ;125:19-29. Epub 2016 Mar 26. PMID: 27021169
Article Published Date : Mar 25, 2016
Authors : Lindsay Joy Spielman, Jonathan Peter Little, Andis Klegeris
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease : CK(4948) : AC(2032), Brain Inflammation : CK(1650) : AC(860), Depressive Disorder : CK(640) : AC(90), Parkinson's Disease : CK(2808) : AC(1032), Schizophrenia : CK(1014) : AC(182)
Therapeutic Actions : Exercise : CK(6247) : AC(935)
Additional Keywords : Physical Activity : CK(518) : AC(58)

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