Focused Research Topics Curcumin & Liver Cancer

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Curcumin Curcumin: Lipidated

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48 Research Articles in Total

The synergistic effects between curcumin and MSCs therapy may hold great promise as a curative combination for HCC.

Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(18):8271-9. PMID: 26745072
Article Published Date : Dec 31, 2014
Authors : Ola M Tork, Eman F Khaleel, Omnia M Abdelmaqsoud
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Anti-Inflammatory Agents : CK(4861) : AC(1630), Interleukin-6 Downregulation : CK(1137) : AC(354), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(1823) : AC(669)

An isocaloric carbohydrate restriction diet and natural AMPK activating agents induce synergistic anticancer effects.

Pubmed Data : Eur J Cancer Prev. 2015 Mar 19. Epub 2015 Mar 19. PMID: 25747515
Article Published Date : Mar 18, 2015
Authors : Jong Doo Lee, Min-Ah Choi, Simon Weonsang Ro, Woo Ick Yang, Arthur E H Cho, Hye-Lim Ju, Sinhwa Baek, Sook In Chung, Won Jun Kang, Mijin Yun, Jeon Han Park
Study Type : In Vitro Study, Transgenic Animal Study
Additional Links
Substances : Catechin : CK(522) : AC(170), Curcumin : CK(4417) : AC(2300), Quercetin : CK(716) : AC(335), Resveratrol : CK(1511) : AC(865)
Diseases : Liver Cancer : CK(1235) : AC(462), Melanoma : CK(285) : AC(149)
Therapeutic Actions : Dietary Modification: Low Carbohydrate : CK(34) : AC(5)
Pharmacological Actions : AMP-activated protein kinase modulation : CK(2) : AC(2), Antiproliferative : CK(2546) : AC(1685), Chemopreventive : CK(2835) : AC(787), Interleukin-6 Downregulation : CK(1137) : AC(354), SIRT1 Activator : CK(39) : AC(23)
Additional Keywords : Diet Induced Tumor Suppression : CK(2) : AC(1)

Curcumin inhibits chemically-induced liver cancer.

Pubmed Data : Food Chem Toxicol. 2000 Nov;38(11):991-5. PMID: 11038236
Article Published Date : Nov 01, 2000
Authors : S E Chuang, A L Cheng, J K Lin, M L Kuo
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Chemically-Induced Liver Damage : CK(634) : AC(255), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Chemopreventive : CK(2835) : AC(787), Hepatoprotective : CK(2523) : AC(1099), NF-kappaB Inhibitor : CK(1114) : AC(694), Tumor Suppressor Protein p53 Upregulation : CK(293) : AC(202)

Curcumin sensitizes human HCC cells to radiation via the suppression of radiation-induced NF-κB activity.

Pubmed Data : Biomed Res Int. 2015 ;2015:363671. Epub 2015 Oct 11. PMID: 26539482
Article Published Date : Dec 31, 2014
Authors : Fei-Ting Hsu, Yu-Chang Liu, Tsu-Te Liu, Jeng-Jong Hwang
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : NF-kappaB Inhibitor : CK(1114) : AC(694), Radiosensitizer : CK(99) : AC(62)

Micellar curcumin in combination with cisplatin can be a promising strategy for treatment of pediatric hepatocellular carcinoma.

Pubmed Data : Oncotarget. 2015 Oct 19. Epub 2015 Oct 19. PMID: 26515460
Article Published Date : Oct 18, 2015
Authors : Nicola Bortel, Sorin Armeanu-Ebinger, Evi Schmid, Bettina Kirchner, Jan Frank, Alexa Kocher, Christina Schiborr, Steven Warmann, Jörg Fuchs, Verena Ellerkamp
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antiproliferative : CK(2546) : AC(1685), Apoptotic : CK(2958) : AC(2075), NF-kappaB Inhibitor : CK(1114) : AC(694), Wnt/β-catenin signaling pathway modulation : CK(36) : AC(24)
Additional Keywords : Chemotherapeutic Synergy: Cisplatin : CK(137) : AC(103)

Curcumin inhibits liver cancer cell invasiveness.

Pubmed Data : Comp Biochem Physiol B Biochem Mol Biol. 2000 Oct;127(2):213-22. PMID: 9663426
Article Published Date : Oct 01, 2000
Authors : L I Lin, Y F Ke, Y C Ko, J K Lin
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Cancer Metastasis : CK(442) : AC(206), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Anti-metastatic : CK(634) : AC(414), Antineoplastic Agents : CK(1158) : AC(639), Matrix metalloproteinase-9 (MMP-9) inhibitor : CK(212) : AC(128)

Curcumin may be a viable anticancer agent in the treatment of HCC.

Pubmed Data : Mol Med Rep. 2014 Nov ;10(5):2505-10. Epub 2014 Sep 9. PMID: 25216080
Article Published Date : Oct 31, 2014
Authors : Wanxing Duan, Yuanhong Chang, Rong Li, Qinhong Xu, Jianjun Lei, Caiqiao Yin, Ting Li, Yanzhao Wu, Qingyong Ma, Xuqi Li
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Hypoxia : CK(123) : AC(60), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Anti-metastatic : CK(634) : AC(414), Antineoplastic Agents : CK(1158) : AC(639), Antiproliferative : CK(2546) : AC(1685), Apoptotic : CK(2958) : AC(2075)

Curcumin suppressed phthalate-induced cell migration, invasion and epithelial-mesenchymal transition, decreased the proportion of CSC-like cells.

Pubmed Data : J Agric Food Chem. 2015 Nov 20. Epub 2015 Nov 20. PMID: 26585812
Article Published Date : Nov 19, 2015
Authors : Cheng-Fang Tsai, Tsung-Hua Hsieh, Jau-Nan Lee, Chia-Yi Hsu, Yu-Chih Wang, Kung-Kai Kuo, Hua-Lin Wu, Chien-Chih Chiu, Eing-Mei Tsai, Po-Lin Kuo
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462), Liver Cancer: Metastatic : CK(23) : AC(10), Phthalate Toxicity : CK(63) : AC(17)
Pharmacological Actions : Anti-metastatic : CK(634) : AC(414)
Additional Keywords : Cancer Stem Cells : CK(228) : AC(153)
Problem Substances : Phthalates : CK(252) : AC(44)
Adverse Pharmacological Actions : Carcinogenic : CK(1000) : AC(144)

High dose of curcumin might be an effective anti-angiogenic drug in the treatment against tumor.

Pubmed Data : Mol Pharmacol.2007 Dec;72(6):1508-21. Epub 2007 Sep 14. PMID: 16151260
Article Published Date : Dec 01, 2007
Authors : P Yoysungnoen, P Wirachwong, P Bhattarakosol, H Niimi, S Patumraj
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Cancer Metastasis : CK(442) : AC(206), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Anti-Angiogenic : CK(197) : AC(137), Anti-metastatic : CK(634) : AC(414)

"Curcumin nanoparticles improve the physicochemical properties of curcumin and effectively enhance its antioxidant and antihepatoma activities."

Pubmed Data : J Agric Food Chem. 2010 Jun 23 ;58(12):7376-82. PMID: 20486686
Article Published Date : Jun 23, 2010
Authors : Feng-Lin Yen, Tzu-Hui Wu, Cheng-Wei Tzeng, Liang-Tzung Lin, Chun-Ching Lin
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Hepatoma : CK(37) : AC(32), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antineoplastic Agents : CK(1158) : AC(639), Antioxidants : CK(8430) : AC(3132)
Additional Keywords : Nanoencapsulated Curcumin : CK(3) : AC(2)

An extract of turmeric and its phenolic constituents inhibit the growth of human hepatoma cell line (HepG2).

Pubmed Data : Acta Pharm. 2016 Sep 1 ;66(3):387-398. PMID: 27383887
Article Published Date : Aug 31, 2016
Authors : Ezzat Abdel-Lateef, Faten Mahmoud, Olfat Hammam, Eman El-Ahwany, Eman El-Wakil, Sherihan Kandil, Hoda Abu Taleb, Mortada El-Sayed, Hanaa Hassenein
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300), Curcuminoids : CK(4681) : AC(2355), Turmeric : CK(5583) : AC(2569)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antiproliferative : CK(2546) : AC(1685), Apoptotic : CK(2958) : AC(2075)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

Embelin and curcumin have a chemopreventive effect against chemically-induced liver cancer.

Pubmed Data : Fitoterapia. 2005 Sep;76(6):549-55. PMID: 16009505
Article Published Date : Sep 01, 2005
Authors : M Sreepriya, Geetha Bali
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300), Embelia ribes : CK(16) : AC(8)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Chemopreventive : CK(2835) : AC(787)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

Curcuminoids can inhibit tumor promotion caused by iron in T51B cells.

Pubmed Data : Nutr Cancer. 2017 Jan 27:1-9. Epub 2017 Jan 27. PMID: 28129008
Article Published Date : Jan 26, 2017
Authors : Donald J Messner, Todd Robinson, Kris V Kowdley
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300), Curcuminoids : CK(4681) : AC(2355), Turmeric : CK(5583) : AC(2569)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Anticarcinogenic Agents : CK(1099) : AC(519), Chemopreventive : CK(2835) : AC(787)

"Curcumin and Liver Cancer: A Review."

Pubmed Data : Curr Pharm Biotechnol. 2011 Apr 5. Epub 2011 Apr 5. PMID: 21466422
Article Published Date : Apr 05, 2011
Authors : Altaf S Darvesh, Bharat B Aggarwal, Anupam Bishayee
Study Type : Review
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)

An overview of natural plant products in the treatment of hepatocellular carcinoma.

Pubmed Data : Anticancer Agents Med Chem. 2018 Jun 3. Epub 2018 Jun 3. PMID: 29866017
Article Published Date : Jun 02, 2018
Authors : Divya Rawat, Somi Shrivastava, Rayees Ahmad Naik, Saurabh Kumar Chhonker, Aditi Mehrotra, Raj Kumar Koiri
Study Type : Review
Additional Links
Substances : Caffeine : CK(245) : AC(40), Curcumin : CK(4417) : AC(2300), Emodin : CK(47) : AC(31), Lycopene : CK(494) : AC(108), Phloretin : CK(96) : AC(46), Quercetin : CK(716) : AC(335), Resveratrol : CK(1511) : AC(865), Silibinin : CK(135) : AC(70), Urolithin A : CK(19) : AC(7)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Chemopreventive : CK(2835) : AC(787)

Astragaloside IV and curcumin alone and in combination significantly reduced mean tumor weight compared to vehicle control.

Pubmed Data : Anticancer Res. 2017 02 ;37(2):465-473. PMID: 28179291
Article Published Date : Dec 31, 2016
Authors : Shuo Zhang, Decai Tang, Wenhua Zang, Gang Yin, Jianguo Dai, Y U Sun, Zhijian Yang, Robert M Hoffman, Xiuxia Guo
Study Type : Animal Study
Additional Links
Substances : Astragaloside : CK(1) : AC(1), Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antiproliferative : CK(2546) : AC(1685), Matrix metalloproteinase-2 (MMP-2) inhibitor : CK(287) : AC(147), MicroRNA modulator : CK(264) : AC(145), Vascular Endothelial Growth Factor Inhibitors : CK(123) : AC(61)
Additional Keywords : Natural Substance Synergy : CK(540) : AC(249)

Both curcumin and carvacrol showed a great efficacy against hepatocellular carcinoma.

Pubmed Data : Asian Pac J Cancer Prev. 2015 ;16(12):4949-54. PMID: 26163620
Article Published Date : Dec 31, 2014
Authors : Hanaa H Ahmed, Wafaa Gh Shousha, Aziza B Shalby, Hatem A El-Mezayen, Nora N Ismaiel, Nadia S Mahmoud
Study Type : Animal Study
Additional Links
Substances : Carvacrol : CK(67) : AC(9), Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Angiogenesis Inhibitors : CK(114) : AC(62), Antiproliferative : CK(2546) : AC(1685), Apoptotic : CK(2958) : AC(2075)
Additional Keywords : Gene Expression Regulation : CK(431) : AC(214)

Cucurbitacin B in the combination with curcumin could serve as a novel, promising approach for human hepatoma.

Pubmed Data : Eur J Pharmacol. 2015 Oct 6. Epub 2015 Oct 6. PMID: 26452516
Article Published Date : Oct 05, 2015
Authors : Yuqi Sun, Jie Zhang, Jiaying Zhou, Ziyuan Huang, Haiyang Hu, Mingxi Qiao, Xiuli Zhao, Dawei Chen
Study Type : Human In Vitro
Additional Links
Substances : Cucurbitacin B : CK(77) : AC(49), Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Apoptotic : CK(2958) : AC(2075)
Additional Keywords : Multidrug Resistance : CK(6) : AC(4), Natural Substance Synergy : CK(540) : AC(249)

Curcumin and tetrahydrocurcumin exhibit anti-cancer properties in liver cancer.

Pubmed Data : World J Gastroenterol. 2008 Apr 7;14(13):2003-9. PMID: 18395899
Article Published Date : Apr 07, 2008
Authors : Pornprom Yoysungnoen, Ponthip Wirachwong, Chatchawan Changtam, Apichart Suksamrarn, Suthiluk Patumraj
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Anti-Angiogenic : CK(197) : AC(137), Antineoplastic Agents : CK(1158) : AC(639)

Curcumin decreases survival of liver and breast cancer cells.

Pubmed Data : Strahlenther Onkol. 2011 Jul ;187(7):393-400. Epub 2011 Jun 27. PMID: 21713389
Article Published Date : Jul 01, 2011
Authors : Mareike Ströfer, Wolfgang Jelkmann, Reinhard Depping
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Breast Cancer : CK(3592) : AC(1064), Hypoxia : CK(123) : AC(60), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antiproliferative : CK(2546) : AC(1685), Apoptotic : CK(2958) : AC(2075), Radiosensitizer : CK(99) : AC(62)

Curcumin exhibits anti-liver cancer activity.

Pubmed Data : Int J Pharm. 2010 Nov 15;400(1-2):211-20. Epub 2010 Sep 8. PMID: 20813175
Article Published Date : Nov 15, 2010
Authors : Jinghua Duan, Yangde Zhang, Shiwei Han, Yuxiang Chen, Bo Li, Mingmei Liao, Wei Chen, Xingming Deng, Jinfeng Zhao, Boyun Huang
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Anti-Angiogenic : CK(197) : AC(137), Apoptotic : CK(2958) : AC(2075)

Curcumin has anticancer activity in human liver cancer cell lines.

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2010 Feb;35(4):485-8. PMID: 20450049
Article Published Date : Feb 01, 2010
Authors : Weizhang Wang, Biyu Zhang, Hongyuan Chen, Li Zhang
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antiproliferative : CK(2546) : AC(1685), Apoptotic : CK(2958) : AC(2075), Cell cycle arrest : CK(810) : AC(612)

Curcumin has been used to successfully treat infantile hemangioendothelioma of the liver.

Pubmed Data : Pediatr Blood Cancer. 2010 Aug;55(2):377-9. PMID: 20582974
Article Published Date : Aug 01, 2010
Authors : Lewis A Hassell, Le Dinh Roanh
Study Type : Human: Case Report
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Hemangioendothelioma : CK(5) : AC(2), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antineoplastic Agents : CK(1158) : AC(639)

Curcumin induces programmed cell death in a variety of cancer cell lines.

Pubmed Data : Nutr Cancer. 1996;26(1):111-20. PMID: 8844727
Article Published Date : Jan 01, 1996
Authors : M C Jiang, H F Yang-Yen, J J Yen, J K Lin
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Colon Cancer : CK(749) : AC(430), Liver Cancer : CK(1235) : AC(462), Sarcoma : CK(68) : AC(38)
Pharmacological Actions : Apoptotic : CK(2958) : AC(2075)

Curcumin induces programmed cell death in human liver cancer cells.

Pubmed Data : Food Chem Toxicol. 2006 Jun;44(6):810-8. Epub 2005 Dec 5. PMID: 16537656
Article Published Date : Jun 01, 2006
Authors : Jun Cao, Li Jia, Hui-Min Zhou, Yong Liu, Lai-Fu Zhong
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : DNA damage : CK(1017) : AC(387), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Apoptotic : CK(2958) : AC(2075)

Curcumin induces programmed cell death in human liver cancer cells.

Pubmed Data : Oncogene. 1996 Aug 1;13(3):609-16. PMID: 8760302
Article Published Date : Aug 01, 1996
Authors : M C Jiang, H F Yang-Yen, J K Lin, J J Yen
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antineoplastic Agents : CK(1158) : AC(639), Apoptotic : CK(2958) : AC(2075), Bcl-2 protein down-regulation : CK(198) : AC(131), Cell cycle arrest : CK(810) : AC(612), Tumor Suppressor Protein p53 Upregulation : CK(293) : AC(202)

Curcumin inhibits aflatoxin-associated DNA adduct formation associated with liver carcinogenesis.

Pubmed Data : Chem Biol Interact. 1996 Mar 8;100(1):41-51. PMID: 8599854
Article Published Date : Mar 08, 1996
Authors : P F Firozi, V S Aboobaker, R K Bhattacharya
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Aflatoxicosis : CK(143) : AC(45), DNA damage : CK(1017) : AC(387), Liver Cancer : CK(1235) : AC(462), Liver Damage: Aflatoxin-Induced : CK(35) : AC(15)

Curcumin inhibits hypoxia-induced angiogenesis associated wtih tumor progression.

Pubmed Data : Oncol Rep. 2006 Jun;15(6):1557-62. PMID: 16685395
Article Published Date : Jun 01, 2006
Authors : Moon-Kyoung Bae, Se-Hee Kim, Joo-Won Jeong, You Mie Lee, Hae-Sun Kim, Su-Ryun Kim, Il Yun, Soo-Kyung Bae, Kyu-Won Kim
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Cancer Metastasis : CK(442) : AC(206), Hypoxia : CK(123) : AC(60), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Anti-Angiogenic : CK(197) : AC(137), Vascular Endothelial Growth Factor A Inhibitor : CK(132) : AC(71)

Curcumin inhibits liver cancer cell gowth.

Pubmed Data : Zhonghua Gan Zang Bing Za Zhi. 2002 Dec;10(6):449-51. PMID: 12502450
Article Published Date : Dec 01, 2002
Authors : Hongyuan Li, Yi Che, Weixue Tang
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antineoplastic Agents : CK(1158) : AC(639), Antiproliferative : CK(2546) : AC(1685), Apoptotic : CK(2958) : AC(2075), Cell cycle arrest : CK(810) : AC(612)

Curcumin inhibits liver tumor angiogenesis and growth.

Pubmed Data : Clin Hemorheol Microcirc. 2006;34(1-2):109-15. PMID: 16543625
Article Published Date : Jan 01, 2006
Authors : Pornprom Yoysungnoen, Porntip Wirachwong, Pavaphon Bhattarakosol, Hideyuki Niimi, Suthiluk Patumraj
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Cancer Metastasis : CK(442) : AC(206), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Anti-Angiogenic : CK(197) : AC(137), Cyclooxygenase 2 Inhibitors : CK(464) : AC(272), Vascular Endothelial Growth Factor A Inhibitor : CK(132) : AC(71)

Curcumin inhibits the proliferation of human liver cancer cells.

Pubmed Data : Int J Mol Med. 2010 Nov;26(5):673-8. PMID: 20878089
Article Published Date : Nov 01, 2010
Authors : Chun-Yuan Cheng, Yi-Hsiang Lin, Chin-Cheng Su
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Apoptotic : CK(2958) : AC(2075)

Curcumin prevents chemically-induced liver cancer.

Pubmed Data : Cancer Lett. 2001 Jun 10;167(1):33-8. PMID: 11323096
Article Published Date : Jun 10, 2001
Authors : S Busquets, N Carbó, V Almendro, M T Quiles, F J López-Soriano, J M Argilés
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antineoplastic Agents : CK(1158) : AC(639), Chemopreventive : CK(2835) : AC(787)

Curcumin prevents chemically-induced liver cancer.

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2007 Mar 30;31(2):439-42. Epub 2006 Dec 15. PMID: 10657978
Article Published Date : Mar 30, 2007
Authors : S E Chuang, M L Kuo, C H Hsu, C R Chen, J K Lin, G M Lai, C Y Hsieh, A L Cheng
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Chemically-Induced Liver Damage : CK(634) : AC(255), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Anticarcinogenic Agents : CK(1099) : AC(519), Chemopreventive : CK(2835) : AC(787)

Curcumin prevents chemically-induced lung and liver tumorigenesis.

Pubmed Data : In Vivo. 2008 Nov-Dec;22(6):781-5. PMID: 19181006
Article Published Date : Nov 01, 2008
Authors : An-Cheng Huang, Shuw-Yuan Lin, Chin-Cheng Su, Song-Shei Lin, Chin-Chin Ho, Te-Chun Hsia, Tsan-Hung Chiu, Chun-Shu Yu, Siu-Wan Ip, Tsung-Ping Lin, Jing-Gung Chung
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462), Lung Cancer : CK(1043) : AC(393)
Pharmacological Actions : Antineoplastic Agents : CK(1158) : AC(639), Chemopreventive : CK(2835) : AC(787)

Curcumin prevents liver cancer metastasis in an animal model.

Pubmed Data : Oncology. 2003;65(3):250-8. PMID: 14657599
Article Published Date : Jan 01, 2003
Authors : Yasukata Ohashi, Yasunori Tsuchiya, Keiichi Koizumi, Hiroaki Sakurai, Ikuo Saiki
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Cancer Metastasis : CK(442) : AC(206), Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antineoplastic Agents : CK(1158) : AC(639)

Curcumin suppresses prevents pre-cancerous changes in the liver of animals.

Pubmed Data : Nutr Cancer. 2003;45(1):53-9. PMID: 12791505
Article Published Date : Jan 01, 2003
Authors : Yogeshwer Shukla, Annu Arora
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Antineoplastic Agents : CK(1158) : AC(639), Hepatoprotective : CK(2523) : AC(1099)

DNC potentially can induce DNA hypomethylation and re-expression of silenced tumor suppressor genes in HCC.

Pubmed Data : Phytomedicine. 2015 Sep 15 ;22(10):961-7. Epub 2015 Jul 14. PMID: 26321746
Article Published Date : Sep 14, 2015
Authors : Mina Zamani, Majid Sadeghizadeh, Mehrdad Behmanesh, Farhood Najafi
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : MicroRNA modulator : CK(264) : AC(145)
Additional Keywords : Epigenetic Modification In Cancer : CK(65) : AC(32), Hypomethylation : CK(13) : AC(3), Reactivation Of Tumor Suppressor Gene : CK(15) : AC(11)

Galactosylated alginate-curcumin conjugate could be used for targeted delivery of curcumin to HepG2 cells.

Pubmed Data : Int J Biol Macromol. 2016 Jan 13. Epub 2016 Jan 13. PMID: 26774374
Article Published Date : Jan 12, 2016
Authors : Sarika P R, Nirmala Rachel James, Anil Kumar P R, Deepa K Raj
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Pharmacological Actions : Cytotoxic : CK(76) : AC(60)
Additional Keywords : Selective Cytotoxicity : CK(158) : AC(112)

Nanocapsulated curcumin acts as an oral chemopreventive formulation against chemically-induced hepatocellular carcinoma in rat.

Pubmed Data : Chem Biol Interact. 2011 Dec 16. Epub 2011 Dec 16. PMID: 22197969
Article Published Date : Dec 16, 2011
Authors : Debasree Ghosh, Somsubhra Thakur Choudhury, Swarupa Ghosh, Ardhendu K Mandal, Sibani Sarkar, Aparajita Ghosh, Krishna Das Saha, Nirmalendu Das
Study Type : Animal Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Chemically-Induced Liver Damage : CK(634) : AC(255), Liver Cancer : CK(1235) : AC(462)
Additional Keywords : Nanoencapsulated Curcumin : CK(3) : AC(2)

Phototherapy strongly enhances the anticancer properties of curcumin in pediatric solid liver tumors in vitro.

Pubmed Data : Anticancer Res. 2016 Jul ;36(7):3363-72. PMID: 27354595
Article Published Date : Jun 30, 2016
Authors : Verena Ellerkamp, Nicola Bortel, Evi Schmid, Bettina Kirchner, Sorin Armeanu-Ebinger, Jörg Fuchs
Study Type : In Vitro Study
Additional Links
Substances : Curcumin : CK(4417) : AC(2300)
Diseases : Liver Cancer : CK(1235) : AC(462)
Therapeutic Actions : Integrative Medicine : CK(312) : AC(45), Photodynamic therapy : CK(81) : AC(23)
Pharmacological Actions : Antiproliferative : CK(2546) : AC(1685), Apoptotic : CK(2958) : AC(2075)

The combination of Curcumin and Berberine is a novel strategy that has potential in the treatment of cancer patients.

Pubmed Data : Biomed Res Int. 2015 ;2015:354614. Epub 2015 Jun 29. PMID: 26247019
Article Published Date : Dec 31, 2014
Authors : Acharya Balakrishna, M Hemanth Kumar
Study Type : In Vitro Study
Additional Links
Substances : Berberine : CK(357) : AC(187), Curcumin : CK(4417) : AC(2300)
Diseases : Acute T cell Leukemias : CK(18) : AC(16), Breast Cancer : CK(3592) : AC(1064), Liver Cancer : CK(1235) : AC(462), Lung Cancer : CK(1043) : AC(393)
Pharmacological Actions : Antiproliferative : CK(2546) : AC(1685)
Additional Keywords : Natural Substance Synergy : CK(540) : AC(249)

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