Focused Research Topics Clogged Arteries & Arginine

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Associated Topics included in this Focused Research

Arterial Calcification Arterial Hardening: Elasticity Arterial Plaque Atherosclerosis Clogged Arteries Coronary Artery Disease Intima Media Thickening

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16 Research Articles in Total

Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis.

Pubmed Data : Breast Cancer Res Treat. 2004 Feb;83(3):221-31. PMID: 19573556
Article Published Date : Feb 01, 2004
Authors : Matthew J Budoff, Naser Ahmadi, Khawar M Gul, Sandy T Liu, Ferdinand R Flores, Jima Tiano, Junichiro Takasu, Elizabeth Miller, Sotirios Tsimikas
Study Type : Human Study
Additional Links
Substances : Arginine : CK(1014) : AC(177), B-complex : CK(278) : AC(32), Garlic : CK(824) : AC(274), Vitamin B-12 : CK(894) : AC(121)
Diseases : Arterial Calcification : CK(186) : AC(29), Atherosclerosis : CK(601) : AC(150), Hypertension : CK(2984) : AC(406)
Pharmacological Actions : Cardioprotective : CK(1596) : AC(409)
Additional Keywords : Plant Extracts : CK(7645) : AC(2539)

L-arginine has a cardioprotective effect in an experimental model of hypercholesterolemic rabbits aorta.

Pubmed Data : Pathophysiology. 2009 Jun;16(1):9-13. Epub 2009 Jan 24. PMID: 19168337
Article Published Date : Jun 01, 2009
Authors : Shaghayegh Haghjooy Javanmard, Mehdi Nematbakhsh, Farzaneh Mahmoodi, Mohamad Reza Mohajeri
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Aortic Stenosis : CK(42) : AC(9), Arterial Plaque : CK(77) : AC(20), Hypercholesterolemia : CK(1428) : AC(227)
Pharmacological Actions : Cardioprotective : CK(1596) : AC(409), Nitric Oxide Enhancer : CK(190) : AC(47)

L-arginine prevents endothelial dysfunction in a hypercholesterolemic rabbit model.

Pubmed Data : Lipids Health Dis. 2008;7:27. Epub 2008 Aug 2. PMID: 18673573
Article Published Date : Jan 01, 2008
Authors : Mehdi Nematbakhsh, Shaghayegh Haghjooyjavanmard, Farzaneh Mahmoodi, Ali Reza Monajemi
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Aortic Plaques : CK(27) : AC(10), Aortic Stenosis : CK(42) : AC(9), Atherosclerosis : CK(601) : AC(150), Endothelial Dysfunction : CK(1210) : AC(237), High Cholesterol : CK(1774) : AC(271), Intima Media Thickening : CK(153) : AC(34)
Pharmacological Actions : Apoptotic : CK(2958) : AC(2075), Cardioprotective : CK(1596) : AC(409)

Arginine may help to prevent atheroma development, in combination with cholesterol reduction.

Pubmed Data : Ann Vasc Surg. 1999 Sep;13(5):484-93. PMID: 10466992
Article Published Date : Sep 01, 1999
Authors : M G Davies, G J Fulton, T T Huynh, L Barber, E Svendsen, P O Hagen
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Atheroma : CK(7) : AC(4), Atherosclerosis : CK(601) : AC(150), Hyperlipidemia : CK(670) : AC(155)
Pharmacological Actions : Hypolipidemic : CK(1288) : AC(265)

Arginine may work synergistically with statin drugs to prevent atherosclerosis development.

Pubmed Data : Ann Biol Clin (Paris). 2005 Sep-Oct;63(5):443-55. PMID: 16230278
Article Published Date : Sep 01, 2005
Authors : C Rasmusen, L Cynober, R Couderc
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Atherosclerosis : CK(601) : AC(150)
Pharmacological Actions : Anticholesteremic Agents : CK(1459) : AC(264), Nitric Oxide Enhancer : CK(190) : AC(47)
Additional Keywords : Drug Synergy : CK(352) : AC(157)

Arginine reduces atheroma (plaque) formation in rabbit vein grafts.

Pubmed Data : J Surg Res. 1995 Jul;59(1):35-42. PMID: 7630134
Article Published Date : Jul 01, 1995
Authors : M G Davies, H Dalen, J H Kim, L Barber, E Svendsen, P O Hagen
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Atheroma : CK(7) : AC(4), Atherosclerosis : CK(601) : AC(150), Intima Media Thickening : CK(153) : AC(34)

Concomitant treatment with oral L-arginine improves the efficacy of surgical angiogenesis in patients with severe diffuse coronary artery disease.

Pubmed Data : J Thorac Cardiovasc Surg. 2008 Apr;135(4):762-70, 770.e1. Epub 2008 Mar 18. PMID: 18374753
Article Published Date : Apr 01, 2008
Authors : Marc Ruel, Robert S Beanlands, Mireille Lortie, Vincent Chan, Nancy Camack, Robert A deKemp, Erik J Suuronen, Fraser D Rubens, Jean N DaSilva, Frank W Sellke, Duncan J Stewart, Thierry G Mesana
Study Type : Human Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Coronary Artery Disease : CK(1488) : AC(157), Coronary Bypass Surgery : CK(142) : AC(15)
Pharmacological Actions : Vascular Endothelial Growth Factor A Inhibitor : CK(132) : AC(71)

L-arginine increases circulating endothelial progenitor cells in hypercholesterolemic rabbits.

Pubmed Data : Int J Cardiol. 2010 Aug 20;143(2):213-6. Epub 2009 Jan 24. PMID: 19167766
Article Published Date : Aug 20, 2010
Authors : Shaghayegh Haghjooy Javanmard, Yousof Gheisari, Masoud Soleimani, Mehdi Nematbakhsh, Alireza Monajemi
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Atherosclerosis : CK(601) : AC(150), High Cholesterol : CK(1774) : AC(271)
Additional Keywords : Endothelial Progenitor Cells (EPCs) : CK(2) : AC(1)

L-arginine potentiates exercise-induced increases in endothelial progenitor cells and VEGF serum levels

Pubmed Data : Int J Cardiol. 2008 Jun 6;126(3):421-3. Epub 2008 Feb 19. PMID: 18243372
Article Published Date : Jun 06, 2008
Authors : Carmela Fiorito, Maria Luisa Balestrieri, Ettore Crimi, Alfonso Giovane, Vincenzo Grimaldi, Pellegrino Biagio Minucci, Luigi Servillo, Francesco Paolo D'Armiento, Bartolomeo Farzati, Claudio Napoli
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Coronary Artery Disease : CK(1488) : AC(157)
Pharmacological Actions : Vascular Endothelial Growth Factor A Enhancer : CK(4) : AC(2)
Additional Keywords : Endothelial Progenitor Cells : CK(8) : AC(7)

L-arginine supplementation improves postsurgical endothelial function, insulin restance and inflammation in nondiabetic patients with coronary artery disease.

Pubmed Data : Metabolism. 2009 Sep;58(9):1270-6. Epub 2009 Jul 9. PMID: 19592054
Article Published Date : Sep 01, 2009
Authors : Pietro Lucotti, Lucilla Monti, Emanuela Setola, Giovanni La Canna, Alessandro Castiglioni, Alessandra Rossodivita, Maria Grazia Pala, Francesco Formica, Giovanni Paolini, Alberico Luigi Catapano, Emanuele Bosi, Ottavio Alfieri, Piermarco Piatti
Study Type : Human Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Coronary Artery Disease : CK(1488) : AC(157), Coronary Bypass Surgery : CK(142) : AC(15)

L-Arginine, the substrate for NO synthesis, may be an alternative treatment for premature atherosclerosis.

Pubmed Data : Int J Cardiol. 2007 Apr 4;116(3):300-8. Epub 2006 Jul 24. PMID: 16860889
Article Published Date : Apr 04, 2007
Authors : Gerasimos Siasos, Dimitris Tousoulis, Charalambos Antoniades, Elli Stefanadi, Christodoulos Stefanadis
Study Type : Human Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Atherosclerosis : CK(601) : AC(150), Endothelial Dysfunction : CK(1210) : AC(237)
Pharmacological Actions : Antihypertensive Agents : CK(1178) : AC(164), Cardiovascular Agents : CK(160) : AC(24), Nitric Oxide Enhancer : CK(190) : AC(47)

L0arginine supplementation improves endothelial function and myocardial perfusion in a swine model of chronic myocardial ischemia.

Pubmed Data : Surgery. 2005 Aug;138(2):291-8. PMID: 16153439
Article Published Date : Aug 01, 2005
Authors : Yasunari Nakai, Pierre Voisine, Cesario Bianchi, Shu-Hua Xu, Jun Feng, Tamer Malik, Audrey Rosinberg, Frank W Sellke
Study Type : Animal Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Coronary Artery Disease : CK(1488) : AC(157), Endothelial Dysfunction : CK(1210) : AC(237), High Cholesterol : CK(1774) : AC(271), Myocardial Ischemia : CK(137) : AC(61)
Pharmacological Actions : Nitric Oxide Inhibitor : CK(223) : AC(108)

Long-term N-acetylcysteine and L-arginine administration reduces endothelial activation and systolic blood pressure in hypertensive patients with type 2 diabetes.

Pubmed Data : Diabetes Care. 2008 May;31(5):940-4. Epub 2008 Feb 11. PMID: 18268065
Article Published Date : May 01, 2008
Authors : Valentino Martina, Andi Masha, Valentina Ramella Gigliardi, Loredana Brocato, Enzo Manzato, Arrigo Berchio, Paola Massarenti, Fabio Settanni, Lara Della Casa, Stefania Bergamini, Anna Iannone
Study Type : Human Study
Additional Links
Substances : Arginine : CK(1014) : AC(177), NAC (N-acetyl-L-cysteine) : CK(318) : AC(76)
Diseases : C-Reactive Protein : CK(1852) : AC(174), Diabetes Mellitus: Type 2 : CK(3572) : AC(624), Endothelial Dysfunction : CK(1210) : AC(237), Fibrinogen: Elevated : CK(104) : AC(12), Hypertension : CK(2984) : AC(406), Intima Media Thickening : CK(153) : AC(34)
Pharmacological Actions : Hypoglycemic Agents : CK(1446) : AC(342), Vascular Cell Adhesion Molecule-1 Inhibitor : CK(117) : AC(30)

Short-term treatment with L-arginine prevents the smoking-induced impairment of endothelial function and vascular elastic properties in young individuals.

Pubmed Data : Int J Cardiol. 2008 Jun 6;126(3):394-9. Epub 2007 Jun 22. PMID: 17588688
Article Published Date : Jun 06, 2008
Authors : Gerasimos Siasos, Dimitris Tousoulis, Charalambos Vlachopoulos, Charalambos Antoniades, Elli Stefanadi, Nikos Ioakeimidis, Ioannis Andreou, Kostas Zisimos, Athanasios G Papavassiliou, Christodoulos Stefanadis
Study Type : Human Study
Additional Links
Substances : Arginine : CK(1014) : AC(177)
Diseases : Arterial Hardening: Elasticity : CK(186) : AC(21), Endothelial Dysfunction : CK(1210) : AC(237), Smoking : CK(740) : AC(111), Tobacco Toxicity : CK(111) : AC(19)

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