Antioxidant Effects

Name	AC	CK
Insulin	2	12
Airborne Pollution	1	10
Benzene	1	10
Arsenic	1	2
Chemotherapy	1	1

Name	AC	CK
Oxidative Stress	15	70
Insulin Resistance	3	21
C-Reactive Protein	2	20
Diabetes Mellitus: Type 2	2	20
Hypertension	5	19
Lipopolysaccharide-Induced Toxicity	2	12
Cardiovascular Diseases	2	11
Air Pollution Linked Toxicity	1	10
Benzene Toxicity	1	10
Chronic Kidney Disease (CKD)	1	10
Chronic Obstructive Pulmonary Disease	1	10
Diabetic Ulcer	1	10
Foot Ulcer	1	10
Hemodialysis	1	10
Inflammation	1	10
Lipid Peroxidation	1	10
Obesity	1	10
Wound Healing	1	10
Cancers	2	6
Liver Cancer	2	6
Cadmium Poisoning	1	5
Leukemia	1	5
Aging: Brain	1	2
Alcoholic Liver Disease	1	2
Arsenic Poisoning	1	2
Autoimmune Diseases	1	2
Cardiomyopathy	1	2
Cognitive Decline/Dysfunction	1	2
Duodenal Ulcer	1	2
Hydrogen Peroxide Induced Toxicity	2	2
Hypercholesterolemia	1	2
Hypoxia	1	2
Liver Fibrosis	1	2
Multiple Sclerosis	1	2
Sepsis	1	2
Skin Cancer: Prevention	1	2
Atherosclerosis	1	1
Cervical Cancer	1	1
Colon Cancer	1	1
Glioblastoma	1	1
Hyperglycemia	1	1
Hyperpigmentation	1	1
Kawasaki Disease	1	1
Liver Cirrhosis	1	1
Neurodegenerative Diseases	1	1
Schizophrenia	1	1
Schizophrenic Disorders	1	1
Ulcerative Colitis	1	1

Name	AC	CK
Sulforaphane	14	38
Green Tea	2	12
Tea	2	12
Broccoli Sprouts	2	11
Capsaicin	1	10
Ginger	1	10
Lemon Balm	1	10
Olive	1	10
Olive Oil	1	10
Resistant Starch	1	10
Spirulina	1	10
Zinc	1	10
Anthocyanins	1	5
Cruciferous Vegetables	1	5
Polyphenols	1	5
DHA (Docosahexaenoic Acid)	2	3
Omega-3 Fatty Acids	2	3
Bacopa	1	2
Black Tea	1	2
Catechin	1	2
Curcumin	2	2
EPA (Eicosapentaenoic Acid)	2	2
Flavonoids	2	2
Ginkgo biloba	1	2
Ginsenosides	1	2
Lion's Mane (Hericium Erinaceus)	1	2
Marshmallow Root	1	2
Resveratrol	1	2
Safflower	1	2
Solanum nigrum (black nightshade)	1	2
Turmeric	2	2
Andrographolide	1	1
Berberine	1	1
Bitter Melon	1	1
Docosahexaenoic acid (DHA)	1	1
Herbs: General	1	1
Honeysuckle	1	1
Whey	1	1
Yarrow	1	1

Name	AC	CK
antioxidant	2	3
neuro-protective	2	3
anti-inflammatory	1	2
antioxidants	1	1

Name	AC	CK
Antioxidant Effects	46	164
Anti-Inflammatory Agents	10	29
Antioxidant	5	23
Malondialdehyde Down-regulation	2	20
Nrf2 activation	8	15
Hypoglycemic Agents	3	13
Antihypertensive Agents	2	12
Antiproliferative	3	12
Superoxide Dismutase Up-regulation	2	12
Apoptotic	3	11
Insulin Sensitizers	2	11
Interleukin-6 Downregulation	2	11
Anticholesteremic Agents	1	10
Detoxifier	1	10
Anticarcinogenic Agents	4	9
Angiotensin-Converting Enzyme Inhibitors	3	7
NF-E2-Related Factor-2 (Nrf2) Modulator	3	7
NF-kappaB Inhibitor	5	7
Neuroprotective Agents	4	6
Autophagy Up-regulation	1	5
Cardioprotective	4	5
NADPH Oxidase Inhibitors	1	5
Vasodilator Agents	1	5
Anti Inflammatory	3	4
Renoprotective	2	4
Antioxidants	2	3
Interleukin-1 beta downregulation	2	3
Anti-Apoptotic	1	2
Anti-Fibrotic	1	2
Anti-atherogenic	2	2
Brain-derived neurotrophic factor modulator	1	2
Gastroprotective	1	2
Hepatoprotective	1	2
Histone deacetylase inhibitor	2	2
Immunomodulatory	1	2
Metallothionein Up-regulation	1	2
Nitric Oxide Inhibitor	1	2
SIRT1 Activator	1	2
Tumor Necrosis Factor (TNF) Alpha Inhibitor	1	2
Anti-Arrhythmia Agents	1	1
Chemosensitizer	1	1
Gastrointestinal Agents	1	1
Glucose Uptake Optimization	1	1
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	1	1
Iron Chelating Agents	1	1
Pancreato Protective Agents	1	1
Phase II Detoxification Enzyme Inducer	1	1

[+]

Chia reduces systolic blood pressure and oxidative stress in hypertensive subjects.Dec 01, 2014

Click here to read the entire abstract

Pubmed Data : Plant Foods Hum Nutr. 2014 Dec ;69(4):392-8. PMID: 25403867

Article Published Date : Dec 01, 2014

Study Type : Human Study

Additional Links

Diseases : Hypertension, Lipid Peroxidation, Oxidative Stress

Pharmacological Actions : Antihypertensive Agents, Antioxidant Effects

[+]

Chinese propolis is effective at improving antioxidant function in T2DM patients, partly by increasing serum antioxidant parameters.Feb 01, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Diabetes Ther. 2018 Feb ;9(1):101-111. Epub 2017 Dec 6. PMID: 29214374

Article Published Date : Feb 01, 2018

Study Type : Human Study

Additional Links

Diseases : Diabetes Mellitus: Type 2

Pharmacological Actions : Antioxidant Effects

[+]

Extra virgin olive oil mitigates postprandial lipopolysaccharide-induced inflammation and oxidative stress.Mar 01, 2019

Click here to read the entire abstract

Pubmed Data : Eur J Nutr. 2019 Mar ;58(2):843-851. Epub 2018 May 16. PMID: 29766292

Article Published Date : Mar 01, 2019

Study Type : Human Study

Additional Links

Substances : Olive, Olive Oil

Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Oxidative Stress

Pharmacological Actions : Antioxidant, Antioxidant Effects

[+]

Lemon balm decreases HbA1c and improves beta-cell activity, blood pressure, and HDL-C in type 2 diabetic individuals.Mar 01, 2019

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2019 Mar ;33(3):651-659. Epub 2018 Dec 10. PMID: 30548118

Article Published Date : Mar 01, 2019

Study Type : Human Study

Additional Links

Substances : Lemon Balm

Diseases : Cardiovascular Diseases, Diabetes Mellitus: Type 2

Pharmacological Actions : Antioxidant Effects, Hypoglycemic Agents

Additional Keywords : Plant Extracts

[+]

Prebiotic-resistant starch supplementation seems to be a promising nutritional strategy to improve inflammation, oxidative stress and to reduce indoxyl sulfate plasma levels in chronic kidney disease patients on hemodialysis.Dec 13, 2018

Click here to read the entire abstract

Pubmed Data : Food Funct. 2018 Dec 13 ;9(12):6508-6516. PMID: 30468238

Article Published Date : Dec 13, 2018

Study Type : Human Study

Additional Links

Substances : Resistant Starch

Diseases : C-Reactive Protein, Chronic Kidney Disease (CKD), Hemodialysis, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidant Effects, Interleukin-6 Downregulation

[+]

Spirulina intake for 30 and 60 days led to a significant reduced serum content of MDA, lipid hydroperoxide, and cholesterol, while increasing GSH and vitamin C level. Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2015 ;2015:486120. Epub 2015 Jan 22. PMID: 25685791

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Spirulina

Diseases : Chronic Obstructive Pulmonary Disease, Oxidative Stress

Pharmacological Actions : Anticholesteremic Agents, Antioxidant Effects, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation

Additional Keywords : Significant Treatment Outcome

[+]

Sulforaphane detoxifies benzene, an air pollutant, in a dose-dependent manner and may attentuate attenuate associated long-term health risks of air pollution. Jul 03, 2019

Click here to read the entire abstract

Pubmed Data : Am J Clin Nutr. 2019 Jul 3. Epub 2019 Jul 3. PMID: 31268126

Article Published Date : Jul 03, 2019

Study Type : Human Study

Additional Links

Substances : Broccoli Sprouts, Sulforaphane

Diseases : Air Pollution Linked Toxicity, Benzene Toxicity

Pharmacological Actions : Antioxidant Effects, Detoxifier

Additional Keywords : Airborne Pollution, Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Dose Response, Environmental Pollutant, Environmental Pollution

Problem Substances : Airborne Pollution, Benzene

[+]

The effects of zinc supplementation on wound healing and metabolic status in patients with diabetic foot ulcer.Apr 30, 2017

Click here to read the entire abstract

Pubmed Data : Wound Repair Regen. 2017 May ;25(3):512-520. Epub 2017 May 9. PMID: 28395131

Article Published Date : Apr 30, 2017

Study Type : Human Study

Additional Links

Substances : Zinc

Diseases : C-Reactive Protein, Diabetic Ulcer, Foot Ulcer, Insulin Resistance, Wound Healing

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidant Effects, Malondialdehyde Down-regulation

[+]

This study found that that taking green tea, capsaicin and ginger co-supplements for 8 weeks among overweight women had beneficial effects on weight, BMI, markers of insulin metabolism and plasma glutathione levels.Jan 01, 2017

Click here to read the entire abstract

Pubmed Data : Ann Nutr Metab. 2017 ;70(4):277-285. Epub 2017 Jun 9. PMID: 28595182

Article Published Date : Jan 01, 2017

Study Type : Human Study

Additional Links

Substances : Capsaicin, Ginger, Green Tea, Tea

Diseases : Insulin Resistance, Obesity, Oxidative Stress

Pharmacological Actions : Antioxidant Effects, Insulin Sensitizers

Additional Keywords : Plant Extracts

Problem Substances : Insulin

[+]

Anthocyanins inhibit the angiotensin-converting enzyme and xanthine oxidase, decrease low density lipoprotein, and increase nitric oxide.Feb 25, 2020

Click here to read the entire abstract

Pubmed Data : Int J Mol Sci. 2020 Feb 25 ;21(5). Epub 2020 Feb 25. PMID: 32106617

Article Published Date : Feb 25, 2020

Study Type : Human In Vitro

Additional Links

Substances : Anthocyanins

Diseases : Hypertension

Pharmacological Actions : Angiotensin-Converting Enzyme Inhibitors, Antioxidant Effects, Vasodilator Agents

[+]

Chokeberry, bilberry, raspberry, and cranberry extract increases adiponectin, decreases leptin, and suppresses adipogenesis/lipogenesis in vitro.Jan 01, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2017 ;12(11):e0188583. Epub 2017 Nov 28. PMID: 29182628

Article Published Date : Jan 01, 2017

Study Type : Human In Vitro

Additional Links

Substances : Polyphenols

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidant Effects

Additional Keywords : Plant Extracts

[+]

Free radicals enhance the activation of Antioxidant Response Element (ARE) by sulforaphane, despite suppression of Nrf2 nuclear accumulation.Jan 20, 2018

Click here to read the entire abstract

Pubmed Data : Free Radic Biol Med. 2018 08 20 ;124:532-540. Epub 2018 Jun 30. PMID: 29969714

Article Published Date : Jan 20, 2018

Study Type : Human In Vitro

Additional Links

Substances : Sulforaphane

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidant Effects, Nrf2 activation

Additional Keywords : Antioxidants, Broccoli, Broccoli Sprouts, Cruciferous Vegetables

[+]

Sulforaphane attentuates cadmium-induced carcinogenesis through Nrf2, antioxidant, and autophagy mechanisms.Jan 15, 2018

Click here to read the entire abstract

Pubmed Data : Toxicol Appl Pharmacol. 2018 08 15 ;353:23-30. Epub 2018 Jun 6. PMID: 29885333

Article Published Date : Jan 15, 2018

Study Type : Human In Vitro

Additional Links

Substances : Sulforaphane

Diseases : Cadmium Poisoning , Cancers

Pharmacological Actions : Anticarcinogenic Agents, Antioxidant, Antioxidant Effects, Apoptotic, Autophagy Up-regulation, NF-E2-Related Factor-2 (Nrf2) Modulator

Additional Keywords : Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates

[+]

Sulforaphane decreases leukemia cell viability in vitro by inhibiting NADPH oxidase enzymes and redox transporter signaling.Jan 01, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:4125297. Epub 2018 Nov 18. PMID: 30581529

Article Published Date : Jan 01, 2018

Study Type : Human In Vitro

Additional Links

Substances : Cruciferous Vegetables, Sulforaphane

Diseases : Leukemia

Pharmacological Actions : Antioxidant, Antioxidant Effects, Antiproliferative , NADPH Oxidase Inhibitors

Additional Keywords : Broccoli, Broccoli Sprouts, Isothiocyanates

[+]

A lipid peroxidation product of DHA exerts cardioprotective effects by activating endothelial Nrf2.Jan 01, 2013

Click here to read the entire abstract

Pubmed Data : PLoS One. 2013 ;8(7):e69415. Epub 2013 Jul 23. PMID: 23936010

Article Published Date : Jan 01, 2013

Study Type : Animal Study

Additional Links

Substances : DHA (Docosahexaenoic Acid), Omega-3 Fatty Acids

Pharmacological Actions : Antioxidant Effects, Antioxidants, Cardioprotective, Nrf2 activation

[+]

Althaea officinalis and Solanum nigrum exhibit gastroprotective and antioxidant potential in rats.Oct 25, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Antioxidants (Basel). 2019 Oct 25 ;8(11). Epub 2019 Oct 25. PMID: 31731465

Article Published Date : Oct 25, 2019

Study Type : Animal Study

Additional Links

Substances : Marshmallow Root, Solanum nigrum (black nightshade)

Diseases : Duodenal Ulcer

Pharmacological Actions : Antioxidant Effects, Gastroprotective

[+]

An extract of Bacopa monniera effectively protects the kidney from hypercholesterolemia-mediated oxido-lipidemic damage.Sep 30, 2014

Click here to read the entire abstract

Pubmed Data : Pharm Biol. 2014 Oct ;52(10):1327-34. Epub 2014 Jul 28. PMID: 25068673

Article Published Date : Sep 30, 2014

Study Type : Animal Study

Additional Links

Substances : Bacopa

Diseases : Hypercholesterolemia

Pharmacological Actions : Antioxidant Effects, Renoprotective

Additional Keywords : Gene Expression Regulation, Plant Extracts

[+]

Dietary catechins lower blood glucose levels, mitigate oxidative stress, and inhibit the angiotension-converting enzyme.Dec 01, 2007

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2007 Dec ;53(6):496-500. PMID: 18202537

Article Published Date : Dec 01, 2007

Study Type : Animal Study

Additional Links

Substances : Catechin , Tea

Diseases : Hypertension, Oxidative Stress

Pharmacological Actions : Antihypertensive Agents, Antioxidant Effects, Hypoglycemic Agents

Problem Substances : Insulin

[+]

GBE supplementation improved cognitive functions by decreasing oxidative damage and increasing the BDNF level in aged female rats.Jan 31, 2015

Click here to read the entire abstract

Pubmed Data : Behav Brain Res. 2015 Feb 1 ;278:453-61. Epub 2014 Oct 30. PMID: 25446810

Article Published Date : Jan 31, 2015

Study Type : Animal Study

Additional Links

Substances : Ginkgo biloba

Diseases : Aging: Brain , Cognitive Decline/Dysfunction, Oxidative Stress

Pharmacological Actions : Antioxidant Effects, Brain-derived neurotrophic factor modulator

[+]

Hericium erinaceus polysaccharide significantly improved the immune and antioxidant functions.Dec 08, 2022

Click here to read the entire abstract

Pubmed Data : Biosci Biotechnol Biochem. 2022 Dec 9. Epub 2022 Dec 9. PMID: 36494196

Article Published Date : Dec 08, 2022

Study Type : Animal Study

Additional Links

Substances : Lion's Mane (Hericium Erinaceus)

Pharmacological Actions : Anti-Apoptotic, Antioxidant Effects, Immunomodulatory

Additional Keywords : Polysaccharides

[+]

Nephroprotective effect of Ginsenoside Rg1 in lipopolysaccharide-induced sepsis.Apr 01, 2024

Click here to read the entire abstract

Pubmed Data : Folia Histochem Cytobiol. 2024 Apr 2. Epub 2024 Apr 2. PMID: 38563049

Article Published Date : Apr 01, 2024

Study Type : Animal Study

Additional Links

Substances : Ginsenosides

Diseases : Lipopolysaccharide-Induced Toxicity, Sepsis

Pharmacological Actions : Antioxidant Effects, NF-kappaB Inhibitor, Renoprotective, SIRT1 Activator

[+]

Protective effects of tea extracts against alcoholic fatty liver disease.Sep 30, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Food Sci Nutr. 2021 Oct ;9(10):5626-5640. Epub 2021 Aug 26. PMID: 34646532

Article Published Date : Sep 30, 2021

Study Type : Animal Study

Additional Links

Substances : Black Tea, Green Tea

Diseases : Alcoholic Liver Disease

Pharmacological Actions : Antioxidant Effects

[+]

Resveratrol attenuates learning, memory, and social interaction impairments in rats exposed to arsenic.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2021 ;2021:9993873. Epub 2021 Sep 28. PMID: 34621902

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Arsenic Poisoning

Pharmacological Actions : Antioxidant Effects, Neuroprotective Agents

Problem Substances : Arsenic

[+]

Sulforaphane protects against intermittent hypoxia-induced cardiomyopathy through Nrf2 activation.Jan 10, 2018

Click here to read the entire abstract

Pubmed Data : Redox Biol. 2018 10 ;19:11-21. Epub 2018 Jul 21. PMID: 30096613

Article Published Date : Jan 10, 2018

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Cardiomyopathy, Hypoxia

Pharmacological Actions : Antioxidant Effects, Metallothionein Up-regulation, Nrf2 activation

Additional Keywords : Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates

[+]

Sulforaphane suppresses an animal model of skin cancer in a pleiotropic manner.Jan 01, 2019

Click here to read the entire abstract

Pubmed Data : Exp Dermatol. 2019 Jan ;28(1):28-34. Epub 2018 Dec 11. PMID: 30315662

Article Published Date : Jan 01, 2019

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Skin Cancer: Prevention

Pharmacological Actions : Anti Inflammatory, Anticarcinogenic Agents, Antioxidant, Antioxidant Effects, Antiproliferative , Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Ultraviolet Radiation Induced Damage

[+]

Sulforaphane's anti-inflammatory, antioxidant, and neuroprotective benefits attentuate autoimmune encephalomyelitis in an animal model of Multiple Sclerosis.Jul 22, 2019

Click here to read the entire abstract

Pubmed Data : J Korean Med Sci. 2019 Jul 22 ;34(28):e197. Epub 2019 Jul 22. PMID: 31327180

Article Published Date : Jul 22, 2019

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Autoimmune Diseases, Multiple Sclerosis

Therapeutic Actions : anti-inflammatory, antioxidant, neuro-protective

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidant Effects, Neuroprotective Agents, Nitric Oxide Inhibitor

Additional Keywords : Antioxidant, Autoimmune Diseases, Cruciferous Vegetables, Multiple Sclerosis, Phytotherapy, Sulforaphane

[+]

The results additionally demonstrated that hydroxysafflor yellow A could enhance superoxide dismutase.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Med Rep. 2017 Jan ;15(1):47-56. Epub 2016 Nov 24. PMID: 27909717

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Safflower

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Antioxidant Effects, Hepatoprotective, Superoxide Dismutase Up-regulation

[+]

Berberine protects Kawasaki disease-induced human coronary artery endothelial cells dysfunction.Feb 14, 2020

Click here to read the entire abstract

Pubmed Data : Vascul Pharmacol. 2020 Feb 15:106660. Epub 2020 Feb 15. PMID: 32070767

Article Published Date : Feb 14, 2020

Study Type : In Vitro Study

Additional Links

Substances : Berberine

Diseases : Kawasaki Disease

Pharmacological Actions : Antioxidant Effects, Cardioprotective

[+]

Buddleja saligna Willd chelates iron, inhibits angiotensin-converting enzyme, acetylcholinesterase, and lipase, and modulates serum lipids and metabolic pathways in vitro.Feb 10, 2020

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2020 Feb 10 ;248:112358. Epub 2019 Oct 30. PMID: 31676404

Article Published Date : Feb 10, 2020

Study Type : In Vitro Study

Additional Links

Substances : Herbs: General

Diseases : Hypertension

Pharmacological Actions : Angiotensin-Converting Enzyme Inhibitors, Antioxidant Effects, Iron Chelating Agents

[+]

Curcumin can reduce blood glucose and HbA1c level by reduction in hepatic glucose production and glycogen synthesis and stimulation of glucose uptake Sep 30, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Endocrinol Metab. 2014 Oct ;12(4):e18081. Epub 2014 Oct 1. PMID: 25745485

Article Published Date : Sep 30, 2014

Study Type : Review

Additional Links

Substances : Curcumin, Turmeric

Diseases : Hyperglycemia, Insulin Resistance

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidant Effects, Hypoglycemic Agents, Insulin Sensitizers

Additional Keywords : Gene Expression Regulation

[+]

Four new cucurbitane-type triterpenes from Momordica charantia L. with their cytotoxic activities and protective effects on H2O2-damaged pancreatic cells.Jun 28, 2019

Click here to read the entire abstract

Pubmed Data : J Nat Med. 2019 Jun 29. Epub 2019 Jun 29. PMID: 31256310

Article Published Date : Jun 28, 2019

Study Type : In Vitro Study

Additional Links

Substances : Bitter Melon

Diseases : Cervical Cancer, Colon Cancer, Glioblastoma, Hydrogen Peroxide Induced Toxicity

Pharmacological Actions : Antioxidant Effects, Pancreato Protective Agents

[+]

Given its anticarcinogenic, anti-inflammatory, antioxidant properties, these authors conclude that sulforaphane could be considered as a phytochemical at the forefront of natural medicine.May 23, 2018

Click here to read the entire abstract

Pubmed Data : Food Funct. 2018 May 23 ;9(5):2589-2606. PMID: 29701207

Article Published Date : May 23, 2018

Study Type : Review

Additional Links

Substances : Sulforaphane

Diseases : Cancers, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidant Effects, Apoptotic, NF-E2-Related Factor-2 (Nrf2) Modulator, NF-kappaB Inhibitor

Additional Keywords : Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates

[+]

Lonicera rupicola Hook.f.et Thoms flavonoids ameliorated dysregulated inflammatory responses, intestinal barrier, and gut microbiome.Jun 23, 2022

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2022 Jun 24 ;104:154284. Epub 2022 Jun 24. PMID: 35777121

Article Published Date : Jun 23, 2022

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids, Honeysuckle

Diseases : Ulcerative Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidant Effects, Gastrointestinal Agents

[+]

Neuroprotective effect of didymin on hydrogen peroxide-induced injury in the neuronal membrane system.Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cells Tissues Organs. 2014 ;199(2-3):184-200. Epub 2014 Nov 18. PMID: 25412833

Article Published Date : Dec 31, 2013

Study Type : In Vitro Study

Additional Links

Substances : Flavonoids

Diseases : Hydrogen Peroxide Induced Toxicity, Neurodegenerative Diseases, Oxidative Stress

Pharmacological Actions : Antioxidant Effects, Neuroprotective Agents

[+]

Sulforaphane pre-treatment effectively protects bovine ovarian granulosa cells from oxidative stress damage through Nrf2-ARE activation.Dec 01, 2018

Click here to read the entire abstract

Pubmed Data : Cell Tissue Res. 2018 Dec ;374(3):629-641. Epub 2018 Jul 21. PMID: 30032437

Article Published Date : Dec 01, 2018

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane

Diseases : Oxidative Stress

Pharmacological Actions : Antioxidant Effects, Nrf2 activation

Additional Keywords : Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Isothiocyanates

[+]

Sulforaphane's antioxidant, anti-inflammatory, and histone deacetylase inhibiting properties may improve schizophrenia symptoms.Jun 28, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2019 Jun 28 ;44(6):701-705. PMID: 31304933

Article Published Date : Jun 28, 2019

Study Type : Review

Additional Links

Substances : Sulforaphane

Diseases : Schizophrenia, Schizophrenic Disorders

Pharmacological Actions : Anti Inflammatory, Antioxidant Effects, Histone deacetylase inhibitor

Additional Keywords : Isothiocyanates

[+]

Sulforphane's antioxidant properties make it an effective neuroprotective agent. More studies are needed to determine the exact implications in neurological disease.Apr 01, 2019

Click here to read the entire abstract

Pubmed Data : Brain Circ. 2019 Apr-Jun;5(2):74-83. Epub 2019 Jun 27. PMID: 31334360

Article Published Date : Apr 01, 2019

Study Type : Review

Additional Links

Substances : Sulforaphane

Therapeutic Actions : antioxidant, antioxidants, neuro-protective

Pharmacological Actions : Antioxidant, Antioxidant Effects, Antioxidants, Neuroprotective Agents, NF-E2-Related Factor-2 (Nrf2) Modulator, Nrf2 activation

Additional Keywords : Antioxidant effects, Antioxidant Systems, Cruciferous Vegetables, Neurodegenerative diseases, Neuroprotective Agents, Nrf2 activation, Phytotherapy, Sulforaphane

[+]

The role of Andrographolide in the prevention and treatment of liver diseases.Dec 31, 2022

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2023 Jan ;109:154537. Epub 2023 Jan 5. PMID: 36610122

Article Published Date : Dec 31, 2022

Study Type : Review

Additional Links

Substances : Andrographolide

Diseases : Liver Cancer, Liver Cirrhosis

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidant Effects, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor

[+]

This review describes the anti-inflammatory and antioxidant effects of oxidized omega-3 fatty acids.Jan 01, 2016

Click here to read the entire abstract

Pubmed Data : Biochimie. 2016 Jan ;120:56-61. Epub 2015 Jun 23. PMID: 26112019

Article Published Date : Jan 01, 2016

Study Type : Review

Additional Links

Substances : Docosahexaenoic acid (DHA), EPA (Eicosapentaenoic Acid), Omega-3 Fatty Acids

Diseases : Atherosclerosis, Cardiovascular Diseases

Pharmacological Actions : Anti-atherogenic, Anti-Inflammatory Agents, Antioxidant Effects, Cardioprotective

Additional Keywords : Cardiovascular Diseases, Inflammation

[+]

This review describes the role of antioxidants like sulforaphane and curcumin in combatting chemoresistance and chemotherapy-induced oxidative stress through NF-kappaB and HIF-1a inhibition.Jun 29, 2019

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2019 Jun 29 ;859:172513. Epub 2019 Jun 29. PMID: 31260654

Article Published Date : Jun 29, 2019

Study Type : Review

Additional Links

Substances : Broccoli Sprouts, Curcumin, Sulforaphane, Turmeric

Pharmacological Actions : Anti Inflammatory, Antioxidant Effects, Chemosensitizer, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, NF-kappaB Inhibitor, Nrf2 activation

Additional Keywords : Anti-cancer, Chemoresistance, Chemosensitizer, Chemotherapy

Problem Substances : Chemotherapy

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This review outlines the bioactivity of certain oxidized fatty acids and mentions the anti-inflammatory, anti-atherogenic, and anti-arrhythmic effects of oxidized docosahexanoic acid (DHA) and eicosapentaenoic acid (EPA).Apr 01, 2015

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Pubmed Data : Biochim Biophys Acta. 2015 Apr ;1851(4):446-55. Epub 2014 Nov 14. PMID: 25463478

Article Published Date : Apr 01, 2015

Study Type : Review

Additional Links

Substances : DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid)

Pharmacological Actions : Anti-Arrhythmia Agents, Anti-atherogenic, Anti-Inflammatory Agents, Antioxidant Effects, Cardioprotective

[+]

This review summarizes the mechanisms, namely through targeting DNA methyltransferases, inhibiting histone deactylases, and activating Nrf2.Jan 01, 2018

Click here to read the entire abstract

Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:5438179. Epub 2018 Jun 6. PMID: 29977456

Article Published Date : Jan 01, 2018

Study Type : Review

Additional Links

Substances : Sulforaphane

Diseases : Oxidative Stress

Pharmacological Actions : Anticarcinogenic Agents, Antioxidant Effects, Histone deacetylase inhibitor, Nrf2 activation

Additional Keywords : DNA Methylation, DNA Methyltransferase, Epigenetic Modification, Isothiocyanates

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This study elucidates the mechanisms behind the neurovascular protective effects of sulforaphane.Aug 23, 2018

Click here to read the entire abstract

Pubmed Data : Sci Rep. 2018 Aug 23 ;8(1):12708. Epub 2018 Aug 23. PMID: 30139948

Article Published Date : Aug 23, 2018

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane

Pharmacological Actions : Antioxidant Effects, Glucose Uptake Optimization, Phase II Detoxification Enzyme Inducer

Additional Keywords : Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Drug Metabolism, Mitochondria, Mitochondrial Biogenesis

[+]

Whey protein concentrate exhibits angiotensin-converting enzyme inhibitory and antioxidant properties.Jan 08, 2020

Click here to read the entire abstract

Pubmed Data : Foods. 2020 Jan 8 ;9(1). Epub 2020 Jan 8. PMID: 31936191

Article Published Date : Jan 08, 2020

Study Type : In Vitro Study

Additional Links

Substances : Whey

Diseases : Hypertension, Oxidative Stress

Pharmacological Actions : Angiotensin-Converting Enzyme Inhibitors, Antioxidant Effects

[+]

Yarrow inhibits melanin production, suggesting it may be beneficial for hyperpigmentation disorders.Jan 01, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2014 ;9(4):e95186. Epub 2014 Apr 17. PMID: 24743745

Article Published Date : Jan 01, 2014

Study Type : In Vitro Study

Additional Links

Substances : Yarrow

Diseases : Hyperpigmentation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidant Effects

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View the Evidence: 45 Abstracts with Antioxidant Effects Research

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Chia reduces systolic blood pressure and oxidative stress in hypertensive subjects.Dec 01, 2014

Chinese propolis is effective at improving antioxidant function in T2DM patients, partly by increasing serum antioxidant parameters.Feb 01, 2018

Extra virgin olive oil mitigates postprandial lipopolysaccharide-induced inflammation and oxidative stress.Mar 01, 2019

Lemon balm decreases HbA1c and improves beta-cell activity, blood pressure, and HDL-C in type 2 diabetic individuals.Mar 01, 2019

Prebiotic-resistant starch supplementation seems to be a promising nutritional strategy to improve inflammation, oxidative stress and to reduce indoxyl sulfate plasma levels in chronic kidney disease patients on hemodialysis.Dec 13, 2018

Spirulina intake for 30 and 60 days led to a significant reduced serum content of MDA, lipid hydroperoxide, and cholesterol, while increasing GSH and vitamin C level. Dec 31, 2014

Sulforaphane detoxifies benzene, an air pollutant, in a dose-dependent manner and may attentuate attenuate associated long-term health risks of air pollution. Jul 03, 2019

The effects of zinc supplementation on wound healing and metabolic status in patients with diabetic foot ulcer.Apr 30, 2017

This study found that that taking green tea, capsaicin and ginger co-supplements for 8 weeks among overweight women had beneficial effects on weight, BMI, markers of insulin metabolism and plasma glutathione levels.Jan 01, 2017

Anthocyanins inhibit the angiotensin-converting enzyme and xanthine oxidase, decrease low density lipoprotein, and increase nitric oxide.Feb 25, 2020

Chokeberry, bilberry, raspberry, and cranberry extract increases adiponectin, decreases leptin, and suppresses adipogenesis/lipogenesis in vitro.Jan 01, 2017

Free radicals enhance the activation of Antioxidant Response Element (ARE) by sulforaphane, despite suppression of Nrf2 nuclear accumulation.Jan 20, 2018

Sulforaphane attentuates cadmium-induced carcinogenesis through Nrf2, antioxidant, and autophagy mechanisms.Jan 15, 2018

Sulforaphane decreases leukemia cell viability in vitro by inhibiting NADPH oxidase enzymes and redox transporter signaling.Jan 01, 2018

A lipid peroxidation product of DHA exerts cardioprotective effects by activating endothelial Nrf2.Jan 01, 2013

Althaea officinalis and Solanum nigrum exhibit gastroprotective and antioxidant potential in rats.Oct 25, 2019

An extract of Bacopa monniera effectively protects the kidney from hypercholesterolemia-mediated oxido-lipidemic damage.Sep 30, 2014

Dietary catechins lower blood glucose levels, mitigate oxidative stress, and inhibit the angiotension-converting enzyme.Dec 01, 2007

GBE supplementation improved cognitive functions by decreasing oxidative damage and increasing the BDNF level in aged female rats.Jan 31, 2015

Hericium erinaceus polysaccharide significantly improved the immune and antioxidant functions.Dec 08, 2022

Nephroprotective effect of Ginsenoside Rg1 in lipopolysaccharide-induced sepsis.Apr 01, 2024

Protective effects of tea extracts against alcoholic fatty liver disease.Sep 30, 2021

Resveratrol attenuates learning, memory, and social interaction impairments in rats exposed to arsenic.Dec 31, 2020

Sulforaphane protects against intermittent hypoxia-induced cardiomyopathy through Nrf2 activation.Jan 10, 2018

Sulforaphane suppresses an animal model of skin cancer in a pleiotropic manner.Jan 01, 2019

Sulforaphane's anti-inflammatory, antioxidant, and neuroprotective benefits attentuate autoimmune encephalomyelitis in an animal model of Multiple Sclerosis.Jul 22, 2019

The results additionally demonstrated that hydroxysafflor yellow A could enhance superoxide dismutase.Dec 31, 2016

Berberine protects Kawasaki disease-induced human coronary artery endothelial cells dysfunction.Feb 14, 2020

Buddleja saligna Willd chelates iron, inhibits angiotensin-converting enzyme, acetylcholinesterase, and lipase, and modulates serum lipids and metabolic pathways in vitro.Feb 10, 2020

Curcumin can reduce blood glucose and HbA1c level by reduction in hepatic glucose production and glycogen synthesis and stimulation of glucose uptake Sep 30, 2014

Four new cucurbitane-type triterpenes from Momordica charantia L. with their cytotoxic activities and protective effects on H2O2-damaged pancreatic cells.Jun 28, 2019

Given its anticarcinogenic, anti-inflammatory, antioxidant properties, these authors conclude that sulforaphane could be considered as a phytochemical at the forefront of natural medicine.May 23, 2018

Lonicera rupicola Hook.f.et Thoms flavonoids ameliorated dysregulated inflammatory responses, intestinal barrier, and gut microbiome.Jun 23, 2022

Neuroprotective effect of didymin on hydrogen peroxide-induced injury in the neuronal membrane system.Dec 31, 2013

Sulforaphane pre-treatment effectively protects bovine ovarian granulosa cells from oxidative stress damage through Nrf2-ARE activation.Dec 01, 2018

Sulforaphane's antioxidant, anti-inflammatory, and histone deacetylase inhibiting properties may improve schizophrenia symptoms.Jun 28, 2019

Sulforphane's antioxidant properties make it an effective neuroprotective agent. More studies are needed to determine the exact implications in neurological disease.Apr 01, 2019

The role of Andrographolide in the prevention and treatment of liver diseases.Dec 31, 2022

This review describes the anti-inflammatory and antioxidant effects of oxidized omega-3 fatty acids.Jan 01, 2016

This review describes the role of antioxidants like sulforaphane and curcumin in combatting chemoresistance and chemotherapy-induced oxidative stress through NF-kappaB and HIF-1a inhibition.Jun 29, 2019

This review outlines the bioactivity of certain oxidized fatty acids and mentions the anti-inflammatory, anti-atherogenic, and anti-arrhythmic effects of oxidized docosahexanoic acid (DHA) and eicosapentaenoic acid (EPA).Apr 01, 2015

This review summarizes the mechanisms, namely through targeting DNA methyltransferases, inhibiting histone deactylases, and activating Nrf2.Jan 01, 2018

This study elucidates the mechanisms behind the neurovascular protective effects of sulforaphane.Aug 23, 2018

Whey protein concentrate exhibits angiotensin-converting enzyme inhibitory and antioxidant properties.Jan 08, 2020

Yarrow inhibits melanin production, suggesting it may be beneficial for hyperpigmentation disorders.Jan 01, 2014

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Antioxidant Effects

View the Evidence:
45 Abstracts with Antioxidant Effects Research