Beta Cell Protection

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15 Diseases Researched for Beta Cell Protection

Name	AC	CK
Diabetes Mellitus: Type 2	9	34
Diabetes Mellitus: Type 1	17	29
Insulin Resistance	2	15
A1C	1	10
Diabetes: Glycation/A1C	1	10
Diabetes Mellitus: Type 1: Prevention	3	5
Prediabetes	1	5
Oxidative Stress	2	4
Diabetes Mellitus: Type 2: Prevention	1	2
Hyperglycemia	1	2
Organ Transplantation: Pancreatic Islet Cells	1	2
Diabetes	1	1
Diabetes: Oxidative Stress	1	1
Endocannabinoid System	1	1
Triglycerides: Elevated	1	1

25 Substances Researched for Beta Cell Protection

Name	AC	CK
Curcumin	4	10
Monounsaturated fatty acids	1	10
Nigella sativa (aka Black Seed)	1	10
Omega-3 Fatty Acids	1	10
Resveratrol	2	4
Astaxanthin	1	2
Chamomile	1	2
EGCG (Epigallocatechin gallate)	1	2
Embelia ribes	1	2
Flaxseed	1	2
Genistein	1	2
Ginseng (American)	2	2
Green Tea	1	2
Gymnema Sylvestre	1	2
Stevia	1	2
Sulforaphane	1	2
Water: Electrolyzed Reduced	1	2
Anthocyanins	1	1
Blueberry	1	1
Cannabinoids	1	1
Cannabis	1	1
Endocannabinoids	1	1
Ginseng, unspecified species	1	1
Oleuropein	1	1
Selenium	1	1

2 Therapeutic Actions Researched for Beta Cell Protection

Name	AC	CK	Focus
Dietary Modification: Low Glycemic Diet	1	10
Fasting/Caloric Restriction	1	2

8 Pharmacological Actions Researched for Beta Cell Protection

Name	AC	CK
Hypoglycemic Agents	2	20
Glucagon Like peptide 1 (GLP-1) Up-regulation	1	10
Insulin Sensitizers	1	10
Antioxidants	4	6
Apoptotic	2	4
NF-kappaB Inhibitor	2	4
Glucose Uptake Optimization	1	2
Insulin-releasing	1	1

Research Articles 25
Cumulative Knowledge Score 40
Overall Research Rating GOOD

View the Evidence:
25 Abstracts with Beta Cell Protection Research

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[+]

A low glycemic and monounsaturated and omega-3 fatty acid rich formula improves metabolic responses in type 2 diabetes. Oct 01, 2008

Click here to read the entire abstract

Pubmed Data : Nutrition. 2008 Oct;24(10):990-7. Epub 2008 Aug 21. PMID: 18718737

Article Published Date : Oct 01, 2008

Study Type : Human Study

Additional Links

Substances : Monounsaturated fatty acids, Omega-3 Fatty Acids

Diseases : Diabetes Mellitus: Type 2

Therapeutic Actions : Dietary Modification: Low Glycemic Diet

Pharmacological Actions : Glucagon Like peptide 1 (GLP-1) Up-regulation, Hypoglycemic Agents

Additional Keywords : Beta Cell Protection

[+]

Black cumin seeds have significant anti-diabetic effects in type 2 diabetics. Oct 01, 2010

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Pubmed Data : Indian J Physiol Pharmacol. 2010 Oct-Dec;54(4):344-54. PMID: 21675032

Article Published Date : Oct 01, 2010

Study Type : Human Study

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : A1C, Diabetes: Glycation/A1C, Diabetes Mellitus: Type 2, Insulin Resistance

Pharmacological Actions : Hypoglycemic Agents, Insulin Sensitizers

Additional Keywords : Beta Cell Protection, Beta Cell Regeneration

[+]

Curcumin extract for prevention of type 2 diabetes.Oct 31, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Diabetes Care. 2012 Nov ;35(11):2121-7. Epub 2012 Jul 6. PMID: 22773702

Article Published Date : Oct 31, 2012

Study Type : Human In Vitro

Additional Links

Substances : Curcumin

Diseases : Diabetes Mellitus: Type 2, Insulin Resistance, Prediabetes

Additional Keywords : Beta Cell Protection, Plant Extracts

[+]

Astaxanthin protects beta-cells against glucose toxicity in diabetic mice. Jan 01, 2002

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Pubmed Data : Redox Rep. 2002;7(5):290-3. PMID: 12688512

Article Published Date : Jan 01, 2002

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Diabetes Mellitus: Type 2

Additional Keywords : Beta Cell Protection

[+]

Chamomile has protective effects against diabetic complications.Jul 01, 2008

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Pubmed Data : Nat Med (Tokyo). 2008 Jul;62(3):284-93. Epub 2008 Feb 13. PMID: 18404309

Article Published Date : Jul 01, 2008

Study Type : Animal Study

Additional Links

Substances : Chamomile

Diseases : Diabetes Mellitus: Type 1

Additional Keywords : Beta Cell Protection

[+]

Curcumin preserves pancreatic islet cell survival and transplantation efficiency. Jan 16, 2008

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Pubmed Data : Life Sci. 2008 Jan 16;82(3-4):182-9. Epub 2007 Nov 21. PMID: 18093618

Article Published Date : Jan 16, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Diabetes Mellitus: Type 1, Organ Transplantation: Pancreatic Islet Cells

Additional Keywords : Beta Cell Protection, Beta Cell Regeneration

[+]

Curcumin protects pancreatic islet cells and chemically-induced type 1 diabetes.Nov 01, 2008

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Pubmed Data : Br J Pharmacol. 2008 Nov;155(5):702-13. Epub 2008 Aug 11. PMID: 18695642

Article Published Date : Nov 01, 2008

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Diabetes Mellitus: Type 1, Oxidative Stress

Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor

Additional Keywords : Beta Cell Protection

[+]

Diet supplementation with green tea extract epigallocatechin gallate prevents progression to glucose intolerance in mice.Feb 14, 2012

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Pubmed Data : Nutr Metab (Lond). 2012 Feb 14 ;9(1):11. Epub 2012 Feb 14. PMID: 22333133

Article Published Date : Feb 14, 2012

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Green Tea

Diseases : Diabetes Mellitus: Type 2

Additional Keywords : Beta Cell Protection

[+]

Electrolyzed reduced water (i.e. structured water) protects against pancreatic cell damage in an animal model of type 1 diabetes. Nov 01, 2002

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Pubmed Data : Cytotechnology. 2002 Nov;40(1-3):139-49. PMID: 19003114

Article Published Date : Nov 01, 2002

Study Type : Animal Study

Additional Links

Substances : Water: Electrolyzed Reduced

Diseases : Diabetes Mellitus: Type 1

Additional Keywords : Beta Cell Protection

[+]

Embelia ribes protects against oxidative stress and pancreatic beta-cell death in experimental diabetes. Jan 01, 2007

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Pubmed Data : Exp Diabetes Res. 2007;2007:15803. PMID: 17641739

Article Published Date : Jan 01, 2007

Study Type : Animal Study

Additional Links

Substances : Embelia ribes

Diseases : Diabetes Mellitus: Type 1

Pharmacological Actions : Antioxidants

Additional Keywords : Beta Cell Protection, Plant Extracts

[+]

Genistein reduces hyperglycemia and pancreatic islet cell loss in a rat model of diabetic pancreatic damage.Feb 01, 2007

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Pubmed Data : J Physiol Sci. 2007 Feb;57(1):43-9. Epub 2007 Jan 6. PMID: 21206328

Article Published Date : Feb 01, 2007

Study Type : Animal Study

Additional Links

Substances : Genistein

Diseases : Diabetes Mellitus: Type 1, Hyperglycemia

Additional Keywords : Beta Cell Protection

[+]

Gymnena sylvestre appears to bring about blood glucose homeostasis through beta cell repair/regeneration.Mar 01, 2008

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Pubmed Data : Evid Based Complement Alternat Med. 2008 Mar;5(1):61-9. PMID: 2259215

Article Published Date : Mar 01, 2008

Study Type : Animal Study

Additional Links

Substances : Gymnema Sylvestre

Diseases : Diabetes Mellitus: Type 1

Additional Keywords : Beta Cell Protection, Beta Cell Regeneration

[+]

Maternal use of flaxseed oil during pregnancy and lactation prevents morphological alterations in pancreas of female offspring from rat dams with experimental diabetes.Mar 24, 2015

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Pubmed Data : Int J Exp Pathol. 2015 Mar 25. Epub 2015 Mar 25. PMID: 25808815

Article Published Date : Mar 24, 2015

Study Type : Animal Study

Additional Links

Substances : Flaxseed

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 1: Prevention, Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention

Additional Keywords : Beta Cell Protection, Transgenerational Epigenetic Modification

[+]

Resveratrol has an ameliorative effect on on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in diabetic rats. Aug 01, 2010

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Pubmed Data : J Cell Physiol. 2010 Aug;224(2):423-32. PMID: 20333650

Article Published Date : Aug 01, 2010

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Diabetes Mellitus: Type 1, Oxidative Stress

Therapeutic Actions : Fasting/Caloric Restriction

Pharmacological Actions : Antioxidants

Additional Keywords : Beta Cell Protection, Stilbenes

[+]

Resveratrol treatment improves glucose tolerance, attenuates β-cell loss, and reduces oxidative stress in type 2 diabetes.Dec 31, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2012 ;7(11):e50412. Epub 2012 Nov 30. PMID: 23226280

Article Published Date : Dec 31, 2011

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Diabetes Mellitus: Type 1

Pharmacological Actions : Glucose Uptake Optimization

Additional Keywords : Beta Cell Protection

[+]

Stevia improves and protects beta-cell function during glucotoxicity. Jun 01, 2007

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Pubmed Data : Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1906-16. Epub 2007 Mar 6 PMID: 17341549

Article Published Date : Jun 01, 2007

Study Type : Animal Study

Additional Links

Substances : Stevia

Diseases : Diabetes Mellitus: Type 1

Additional Keywords : Beta Cell Protection

[+]

Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway.Feb 15, 2009

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Pubmed Data : Toxicol Appl Pharmacol. 2009 Feb 15;235(1):57-67. Epub 2008 Nov 21. PMID: 19071154

Article Published Date : Feb 15, 2009

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 1: Prevention

Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor

Additional Keywords : Beta Cell Protection, Beta Cell Regeneration

[+]

American ginseng prevents beta cell death, increases insulin production and lowers postprandial glucose levels. Oct 25, 2007

Click here to read the entire abstract

Pubmed Data : Chin Med. 2007 Oct 25;2:11. PMID: 17961234

Article Published Date : Oct 25, 2007

Study Type : Review

Additional Links

Substances : Ginseng (American)

Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2

Additional Keywords : Beta Cell Protection

[+]

American Ginseng Stimulates Insulin Production and Prevents Beta Cell Death. Sep 01, 2006

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Pubmed Data : Evid Based Complement Alternat Med. 2006 Sep;3(3):365-72. PMID: 16951721

Article Published Date : Sep 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Ginseng (American)

Diseases : Diabetes Mellitus: Type 1

Pharmacological Actions : Insulin-releasing

Additional Keywords : Beta Cell Protection

[+]

An anthocyanin enriched extract of wild Chinese blueberry could effectively protect β-cells against glucolipotoxicity in vitro.Apr 30, 2015

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Pubmed Data : J Food Sci Technol. 2015 May ;52(5):3022-9. Epub 2014 Apr 26. PMID: 25892804

Article Published Date : Apr 30, 2015

Study Type : In Vitro Study

Additional Links

Substances : Anthocyanins, Blueberry

Diseases : Diabetes, Diabetes: Oxidative Stress, Triglycerides: Elevated

Pharmacological Actions : Antioxidants

Additional Keywords : Beta Cell Protection, Natural Substances Versus Drugs

[+]

Cannabinoids and endocannabinoids may have therapeutic value in metabolic disorders and diabetes.Jan 01, 2011

Click here to read the entire abstract

Pubmed Data : Handb Exp Pharmacol. 2011(203):75-104. PMID: 21484568

Article Published Date : Jan 01, 2011

Study Type : Review

Additional Links

Substances : Cannabinoids , Cannabis, Endocannabinoids

Diseases : Diabetes Mellitus: Type 1: Prevention, Diabetes Mellitus: Type 2, Endocannabinoid System

Additional Keywords : Beta Cell Protection

[+]

Ginseng may beta cell destruction which contributes to its antidiabetic influence in type 1 diabetes.Apr 18, 2007

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2007 Apr 18;55(8):2816-23. Epub 2007 Mar 24. PMID: 17381103

Article Published Date : Apr 18, 2007

Study Type : In Vitro Study

Additional Links

Substances : Ginseng, unspecified species

Diseases : Diabetes Mellitus: Type 1

Additional Keywords : Beta Cell Protection

[+]

Oleuropein may prevent pancreatic famyloid deposits of amylin which is associated with the pathogenesis of type 2 diabetes. Jul 17, 2009

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2009 Jul 17. Epub 2009 Jul 17. PMID: 19616928

Article Published Date : Jul 17, 2009

Study Type : In Vitro Study

Additional Links

Substances : Oleuropein

Diseases : Diabetes Mellitus: Type 2

Additional Keywords : Beta Cell Protection

[+]

Prophylactic use of curcumin may effectively rescue pancreatic islets from damage without affecting the normal function of these cellular structures.Jun 01, 2002

Click here to read the entire abstract

Pubmed Data : BJU Int. 2002 Jun;89(9):829-34. PMID: 17900558

Article Published Date : Jun 01, 2002

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Diabetes Mellitus: Type 1

Pharmacological Actions : Antioxidants

Additional Keywords : Beta Cell Protection

[+]

Selenium may promote beta cell function improvement.Jun 25, 2008

Click here to read the entire abstract

Pubmed Data : FEBS Lett. 2008 Jun 25;582(15):2333-7. Epub 2008 Jun 4. PMID: 18538137

Article Published Date : Jun 25, 2008

Study Type : In Vitro Study

Additional Links

Substances : Selenium

Diseases : Diabetes Mellitus: Type 1

Additional Keywords : Beta Cell Protection

Research Articles 25
Cumulative Knowledge Score 40
Overall Research Rating GOOD