Blood Brain Barrier

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12 Problem Substances Researched for Blood Brain Barrier
NameACCKFocus
Bisphenol A 110Locked
Bisphenol F110Locked
Polystyrene nanoparticles36Locked
Mercury15Locked
Cell Phone Exposure23Locked
Antibiotics12Locked
Nano Plastic-and Micro-Particles12Locked
Aluminum11Locked
Glyphosate11Locked
Morphine11Locked
Polysorbate 8011Locked
Vaccine Adjuvants11Locked
51 Diseases Researched for Blood Brain Barrier
NameACCKFocus
Alzheimer's Disease1540Locked
Brain Inflammation 621Locked
Cerebral Ischemia816Locked
Stroke: Ischemic615Locked
HIV Infections313Locked
Parkinson's Disease413Locked
Anxiety211Locked
Glioblastoma211Locked
Memory Disorders211Locked
Aging: Brain 110Locked
Autism Spectrum Disorders210Locked
Bisphenol Toxicity110Locked
Stress110Locked
Brain Injury: Traumatic47Locked
Stroke: Attenuation/Recovery 27Locked
Microplastic Toxicity36Locked
Multiple Sclerosis36Locked
Neurodegenerative Diseases66Locked
Autism15Locked
Subarachnoid hemorrhage24Locked
Dementia23Locked
Stroke23Locked
Antibiotic Toxicity 12Locked
Brain Ischemia12Locked
Brain: Microglial Activation12Locked
Cerebral Hypoperfusion12Locked
Dysbiosis12Locked
Hemorrhage: Cerebral12Locked
High Fructose Diet12Locked
Hyperglycemia12Locked
Hyperuricemia12Locked
Intracerebral Hemorrhage12Locked
Lipopolysaccharide-Induced Toxicity12Locked
Oxidative Stress22Locked
Postmenopausal Disorders12Locked
Psychiatric Disorders12Locked
Traumatic Brain Injury12Locked
Vitamin D Deficiency12Locked
Alcohol Toxicity 11Locked
Amnesia11Locked
Autoimmune Diseases11Locked
Autoimmune Syndrome Induced by Adjuvants (ASIA)11Locked
Brain Edema11Locked
Central Nervous System Diseases11Locked
Depression11Locked
Diabetes: Cognitive Dysfunction11Locked
Epilepsy11Locked
Glial Cell Tumors11Locked
Glyphosate Toxicity11Locked
Hypertension11Locked
Inflammation11Locked
6 Problematic Actions Researched for Blood Brain Barrier
NameACCKFocus
Electroconvulsive Therapy423Locked
Electromagnetic Field Harms23Locked
Electromagnetic Radiation23Locked
Microwave Radiation23Locked
Mobile Phone Radiation23Locked
Vaccination: All11Locked
5 Adverse Pharmacological Actions Researched for Blood Brain Barrier
NameACCKFocus
Blood Brain Barrier Injury510Locked
Inflammatory26Locked
Interleukin-6 up-regulation15Locked
Vascular Endothelial Growth Factor C Up-Regulation15Locked
Neurotoxic23Locked
53 Substances Researched for Blood Brain Barrier
NameACCKFocus
Curcumin322Locked
Olive Oil215Locked
Ginsenosides612Locked
Resveratrol212Locked
Cannabis110Locked
Curcuminoids110Locked
Fenugreek110Locked
Fiber110Locked
Omega-3 Fatty Acids110Locked
Oleocanthal27Locked
Cannabidiol26Locked
Melatonin46Locked
Flavonoids23Locked
Aloe Vera12Locked
Apigenin12Locked
Baicalein12Locked
Beta-Caryophyllene12Locked
Carvacrol12Locked
Citrus naringin12Locked
DHA (Docosahexaenoic Acid)22Locked
Fisetin12Locked
Ginkgo biloba12Locked
Goji12Locked
Kaempferol12Locked
Ligustrazine12Locked
Magnesium Sulfate12Locked
Magnolol12Locked
Mangosteen22Locked
Mulberry12Locked
Peony12Locked
Prickly Pear Cactus12Locked
Quercetin12Locked
Royal Jelly12Locked
Saffron12Locked
Salvia divinorum12Locked
Sesamin12Locked
Stilbenes12Locked
Tanshinone IIA12Locked
Vitamin D12Locked
6-Shogaol11Locked
Anthocyanins11Locked
Astaxanthin11Locked
Cannabinoids 11Locked
Crocetin11Locked
Ginger11Locked
Gingerol 11Locked
Lotus 11Locked
Naringenin 11Locked
Pomegranate11Locked
Rooibos11Locked
Rutin11Locked
Thymoquinone11Locked
Xanthones11Locked
4 Therapeutic Actions Researched for Blood Brain Barrier
NameACCKFocus
Ultrasound110Locked
Electroacupuncture24Locked
Exercise12Locked
Music12Locked
29 Pharmacological Actions Researched for Blood Brain Barrier
NameACCKFocus
Neuroprotective Agents52128Locked
Anti-Inflammatory Agents1436Locked
Antioxidants1123Locked
Anti-Anxiety Agents211Locked
Chemotherapeutic110Locked
Anti-Apoptotic46Locked
Vascular Cell Adhesion Molecule-1 Inhibitor 15Locked
Immunomodulatory24Locked
Interleukin-1 beta downregulation24Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor34Locked
NF-kappaB Inhibitor24Locked
Angiogenesis Inducing Agents13Locked
Autophagy Up-regulation12Locked
Gastrointestinal Agents12Locked
Gastroprotective12Locked
Interleukin-18 down-regulation12Locked
Neuromodulatory12Locked
Prophylactic Agents12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
Wnt/β-catenin signaling pathway modulation12Locked
Anti-metastatic11Locked
Antidepressive Agents11Locked
Antiproliferative 11Locked
Apoptotic11Locked
Autophagy Inhibitors11Locked
Chelating Agents11Locked
Heme oxygenase-1 inducer11Locked
Neuritogenic11Locked
Telomerase Inhibitor11Locked

View the Evidence:
88 Abstracts with Blood Brain Barrier Research

[+]

Bisphenols accumulation in the white matter-enriched brain tissue could signify that they are able to cross the blood-brain barrier.May 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 May 29 ;8(1):8186. Epub 2018 May 29. PMID: 29844501
Article Published Date : May 28, 2018
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity
Additional Keywords : Blood Brain Barrier
Problem Substances : Bisphenol A , Bisphenol F
[+]

Cannabis may have a beneficial impact on HIV-associated blood-brain barrier injury.Apr 15, 2020

Pubmed Data : Clin Infect Dis. 2020 Apr 16. Epub 2020 Apr 16. PMID: 32296832
Article Published Date : Apr 15, 2020
Study Type : Human Study
Additional Links
Substances : Cannabis
Diseases : HIV Infections
Additional Keywords : Blood Brain Barrier
[+]

Extra-virgin olive oil enhances the blood-brain barrier function in mild cognitive impairment.Nov 30, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Dec 1 ;14(23). Epub 2022 Dec 1. PMID: 36501136
Article Published Date : Nov 30, 2022
Study Type : Human Study
Additional Links
Substances : Olive Oil
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Influence of electroconvulsive therapy on white matter structure in a diffusion tensor imaging study.Mar 31, 2020

Pubmed Data : Psychol Med. 2020 Apr ;50(5):849-856. Epub 2019 Apr 23. PMID: 31010441
Article Published Date : Mar 31, 2020
Study Type : Human Study
Additional Links
Additional Keywords : Blood Brain Barrier
Anti Therapeutic Actions : Electroconvulsive Therapy
[+]

Omega-3 fatty acids are associated with blood-brain barrier integrity in a healthy aging population.Jul 28, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Brain Behav. 2021 Jul 29. Epub 2021 Jul 29. PMID: 34327870
Article Published Date : Jul 28, 2021
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Aging: Brain
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Post-ECT increases in MRI regional T2 relaxation times in the right and left thalumus are linked to memory impairment in depressed patients.Oct 31, 1994

Pubmed Data : Psychiatry Res. 1994 Nov ;54(2):177-84. PMID: 7761551
Article Published Date : Oct 31, 1994
Study Type : Human Study
Additional Links
Diseases : Memory Disorders
Additional Keywords : Blood Brain Barrier
Anti Therapeutic Actions : Electroconvulsive Therapy
[+]

Pulsed ultrasound has the potential to optimize chemotherapy or phytochemical delivery in the brain.Jun 14, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Transl Med. 2016 Jun 15 ;8(343):343re2. PMID: 27306666
Article Published Date : Jun 14, 2016
Study Type : Human Study
Additional Links
Diseases : Glioblastoma
Therapeutic Actions : Ultrasound
Pharmacological Actions : Chemotherapeutic
Additional Keywords : Blood Brain Barrier
[+]

Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer's disease.Oct 19, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurology. 2015 Oct 20 ;85(16):1383-91. Epub 2015 Sep 11. PMID: 26362286
Article Published Date : Oct 19, 2015
Study Type : Human Study
Additional Links
Substances : Resveratrol
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

The effect of curcumin on idiopathic Parkinson disease.May 12, 2022

Pubmed Data : J Neuropathol Exp Neurol. 2022 May 13. Epub 2022 May 13. PMID: 35556131
Article Published Date : May 12, 2022
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

The study demonstrated the safety, tolerance, and enhanced efficacy of CGM in comparison with unformulated standard curcumin.May 31, 2016

Pubmed Data : J Clin Psychopharmacol. 2016 Jun ;36(3):236-43. PMID: 27043120
Article Published Date : May 31, 2016
Study Type : Human Study
Additional Links
Substances : Curcumin, Curcuminoids, Fenugreek, Fiber
Diseases : Anxiety, Stress
Pharmacological Actions : Anti-Anxiety Agents, Antioxidants
Additional Keywords : Blood Brain Barrier, Plant Extracts
[+]

Data suggest that activity at the BBB could represent an as yet unrecognised mechanism of CBD-induced neuroprotection in ischaemic strokeOct 23, 2015

Pubmed Data : Br J Pharmacol. 2015 Oct 24. Epub 2015 Oct 24. PMID: 26497782
Article Published Date : Oct 23, 2015
Study Type : Human In Vitro
Additional Links
Substances : Cannabidiol
Diseases : Stroke: Attenuation/Recovery , Stroke: Ischemic
Pharmacological Actions : Neuroprotective Agents, Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords : Blood Brain Barrier
[+]

Findings from in vivo and in vitro studies provide further support for the protective effect of Oleocanthal against the progression of Alzheimer's Disease.Sep 15, 2015

Pubmed Data : ACS Chem Neurosci. 2015 Sep 16. Epub 2015 Sep 16. PMID: 26348065
Article Published Date : Sep 15, 2015
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Oleocanthal, Olive Oil
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Mercury stimulates VEGF and IL-6 release from human mast cells which could disrupt the blood-brain-barrier and permit brain inflammation.Mar 11, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2010 Mar 11 ;7:20. Epub 2010 Mar 11. PMID: 20222982
Article Published Date : Mar 11, 2010
Study Type : Human In Vitro
Additional Links
Diseases : Autism, Autism Spectrum Disorders, Brain Inflammation
Additional Keywords : Blood Brain Barrier, Heavy Metals and Autism, Vaccine Research
Problem Substances : Mercury
Adverse Pharmacological Actions : Blood Brain Barrier Injury, Inflammatory, Interleukin-6 up-regulation, Vascular Endothelial Growth Factor C Up-Regulation
[+]

These results seem to point to a dysfunctional gut–brain axis associated with neuroinflammation in autism spectrum disorders. Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Autism. 2016 ;7:49. Epub 2016 Nov 29. PMID: 27957319
Article Published Date : Dec 31, 2015
Study Type : Human In Vitro
Additional Links
Diseases : Autism Spectrum Disorders
Additional Keywords : Blood Brain Barrier, Gut-brain Axis
[+]

The ginsenoside Rg1 nanoparticles may be an available blood-brain barrier penetrating agent for ischemic stroke.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nanomedicine. 2022 ;17:5447-5468. Epub 2022 Nov 18. PMID: 36426373
Article Published Date : Dec 31, 2021
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Stroke: Ischemic
Pharmacological Actions : Angiogenesis Inducing Agents, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Aloin protects against blood-brain barrier damage after traumatic brain injury in mice.May 31, 2020

Pubmed Data : Neurosci Bull. 2020 Jun ;36(6):625-638. Epub 2020 Feb 25. PMID: 32100248
Article Published Date : May 31, 2020
Study Type : Animal Study
Additional Links
Substances : Aloe Vera
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Apigenin could attenuate early brain injury after subarachnoid hemorrhage in rats by suppressing TLR4-mediated inflammation and protecting against BBB disruption.May 27, 2015

Pubmed Data : Int Immunopharmacol. 2015 May 28 ;28(1):79-87. Epub 2015 May 28. PMID: 26028151
Article Published Date : May 27, 2015
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Stroke: Attenuation/Recovery , Subarachnoid hemorrhage
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Blood Brain Barrier
[+]

Baicalein exerts a protective effect on blood-brain barrier disruption in the rat model of Intracerebral hemorrhage.Aug 11, 2016

Pubmed Data : Neurochem Res. 2016 Aug 12. Epub 2016 Aug 12. PMID: 27518088
Article Published Date : Aug 11, 2016
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Hemorrhage: Cerebral
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Carvacrol decreases blood-brain barrier permeability post-diffuse traumatic brain injury.Sep 03, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2023 Sep 4 ;13(1):14546. Epub 2023 Sep 4. PMID: 37666857
Article Published Date : Sep 03, 2023
Study Type : Animal Study
Additional Links
Substances : Carvacrol
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Antioxidants, Matrix metalloproteinase-9 (MMP-9) inhibitor, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Effects of isosakuranetin on cerebral infarction and blood brain barrier damage from cerebral ischemia/reperfusion injury.Apr 27, 2023

Pubmed Data : J Biomol Struct Dyn. 2023 Apr 28:1-8. Epub 2023 Apr 28. PMID: 37114509
Article Published Date : Apr 27, 2023
Study Type : Animal Study
Additional Links
Substances : Flavonoids
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Electroacupuncture can significantly improve the learning and memory ability of vascular dementia.Oct 24, 2022

Pubmed Data : Zhen Ci Yan Jiu. 2022 Oct 25 ;47(10):885-90. PMID: 36301165
Article Published Date : Oct 24, 2022
Study Type : Animal Study
Additional Links
Diseases : Dementia
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Electroacupuncture on GV20 can improve neurological function deficits and reduce BBB permeability after spontaneous intracerebral hemorrhage.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Plast. 2016 ;2016:7308261. Epub 2016 Aug 20. PMID: 27725888
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Intracerebral Hemorrhage
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Electroconvulsive shock increases interstitial concentrations of uric acid in the rat brain.Oct 09, 1994

Pubmed Data : Brain Res. 1994 Oct 10 ;660(1):50-6. PMID: 7828001
Article Published Date : Oct 09, 1994
Study Type : Animal Study
Additional Links
Diseases : Hyperuricemia
Additional Keywords : Blood Brain Barrier
Anti Therapeutic Actions : Electroconvulsive Therapy
[+]

Exposure to pulsed electromagnetic field results in changes to blood brain barrier permeability.Apr 01, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Environ Sci. 2012 Apr ;25(2):197-202. PMID: 22998827
Article Published Date : Apr 01, 2012
Study Type : Animal Study
Additional Links
Additional Keywords : Blood Brain Barrier, EMF
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation
Problem Substances : Cell Phone Exposure
Adverse Pharmacological Actions : Blood Brain Barrier Injury
[+]

Ginkgo biloba extract improves brain uptake of ginsenosides by increasing blood-brain barrier permeability.Jan 09, 2020

Pubmed Data : J Ethnopharmacol. 2020 Jan 10 ;246:112243. Epub 2019 Sep 18. PMID: 31541722
Article Published Date : Jan 09, 2020
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba, Ginsenosides
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Ginsenoside Rb1 may offer a potential therapeutic option for patients with HIV-associated neurocognitive disorders.Dec 31, 2017

Pubmed Data : Am J Chin Med. 2018 ;46(3):551-566. PMID: 29690789
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : HIV Infections
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Ginsenoside Rd attenuates blood-brain barrier damage by suppressing proteasome-mediated signaling after transient forebrain ischemia.Mar 11, 2020

Pubmed Data : Neuroreport. 2020 Mar 12. Epub 2020 Mar 12. PMID: 32168101
Article Published Date : Mar 11, 2020
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Brain Ischemia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Ginsenoside Rg1 nanoparticles could penetrate the blood-brain barrier with high concentration in brain tissue to reduce the cerebral infarction volume.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nanomedicine. 2017 ;12:6477-6486. Epub 2017 Sep 5. PMID: 28919749
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Ginsenosides
Diseases : Stroke
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Gintonin may be an herbal medicine-derived candidate to overcome the blood-brain barrier.Jul 14, 2018

Pubmed Data : Int J Biol Macromol. 2018 Jul 15 ;114:1325-1337. Epub 2018 Mar 29. PMID: 29604355
Article Published Date : Jul 14, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Additional Keywords : Blood Brain Barrier, Plant Extracts
[+]

Indicaxanthin was found to cross the blood brain barrier and modulate glutamate-induced neuronal excitation.Jul 30, 2015

Pubmed Data : J Agric Food Chem. 2015 Jul 31. Epub 2015 Jul 31. PMID: 26227670
Article Published Date : Jul 30, 2015
Study Type : Animal Study
Additional Links
Substances : Prickly Pear Cactus
Pharmacological Actions : Neuromodulatory
Additional Keywords : Blood Brain Barrier, Dose Response
[+]

Kaempferol attenuates neuroinflammation and blood brain barrier dysfunction to improve neurological deficits in cerebral ischemia/reperfusion.Jul 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Brain Res. 2019 Aug 1:146361. Epub 2019 Aug 1. PMID: 31377105
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Kaempferol
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor
Additional Keywords : Blood Brain Barrier
[+]

Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behaviour.Apr 03, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nat Commun. 2017 Apr 4 ;8:15062. Epub 2017 Apr 4. PMID: 28375200
Article Published Date : Apr 03, 2017
Study Type : Animal Study
Additional Links
Diseases : Antibiotic Toxicity , Psychiatric Disorders
Additional Keywords : Blood Brain Barrier, Gut-brain Axis, Microbiota
Problem Substances : Antibiotics
[+]

Lycium Barbarum polysaccharides ameliorates hyperglycemia-exacerbated cerebral ischemia/reperfusion injury.Nov 23, 2022

Pubmed Data : Transpl Immunol. 2022 Nov 24 ;76:101757. Epub 2022 Nov 24. PMID: 36436794
Article Published Date : Nov 23, 2022
Study Type : Animal Study
Additional Links
Substances : Goji
Diseases : Cerebral Ischemia, Hyperglycemia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier, Polysaccharides
[+]

Magnesium sulfate protects blood-brain barrier integrity and reduces brain edema after acute ischemic strokeJul 31, 2019

Pubmed Data : Metab Brain Dis. 2019 Aug ;34(4):1221-1229. Epub 2019 Apr 29. PMID: 31037556
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Magnesium Sulfate
Diseases : Stroke: Ischemic
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Magnolol has beneficial effects on cerebral injury and blood brain barrier dysfunction induced by ischemia-reperfusion.Jul 31, 2017

Pubmed Data : Metab Brain Dis. 2017 Aug ;32(4):1109-1118. Epub 2017 Apr 4. PMID: 28378105
Article Published Date : Jul 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Magnolol
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Blood Brain Barrier
[+]

Melatonin alleviates lipopolysaccharide induced blood-brain barrier disruption.Feb 02, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging Cell. 2017 Feb 3. Epub 2017 Feb 3. PMID: 28156052
Article Published Date : Feb 02, 2017
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Melatonin reduces excitotoxic blood-brain barrier breakdown in neonatal rats.Nov 01, 2015

Pubmed Data : Neuroscience. 2015 Nov 2. Epub 2015 Nov 2. PMID: 26542996
Article Published Date : Nov 01, 2015
Study Type : Animal Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Micro and nanoplastics breach the blood-brain barrier.Apr 18, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nanomaterials (Basel). 2023 Apr 19 ;13(8). Epub 2023 Apr 19. PMID: 37110989
Article Published Date : Apr 18, 2023
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity
Additional Keywords : Blood Brain Barrier
Problem Substances : Polystyrene nanoparticles
[+]

Mulberroside A was capable of preventing high fructose diet-induced damage of intestinal epithelial barrier and blood-brain barrier.Dec 31, 2020

Pubmed Data : J Neurochem. 2021 06 ;157(6):1979-1991. Epub 2020 Nov 30. PMID: 33205422
Article Published Date : Dec 31, 2020
Study Type : Animal Study
Additional Links
Substances : Mulberry, Stilbenes
Diseases : Brain Inflammation , Dysbiosis, High Fructose Diet
Pharmacological Actions : Gastrointestinal Agents, Gastroprotective, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Naringin could be a potential therapeutic agent to prevent the brain from ischemia-reperfusion injury.Nov 30, 2018

Pubmed Data : Mol Neurobiol. 2018 Dec ;55(12):9029-9042. Epub 2018 Apr 7. PMID: 29627876
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Citrus naringin
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Oleocanthal and extra-virgin olive oil could provide beneficial effect to slow or halt the progression of Alzheimer's disease.Aug 20, 2019

Pubmed Data : ACS Chem Neurosci. 2019 Aug 21 ;10(8):3543-3554. Epub 2019 Jun 25. PMID: 31244050
Article Published Date : Aug 20, 2019
Study Type : Animal Study
Additional Links
Substances : Oleocanthal
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Orally administered fisetin crosses the blood-brain barrier and promotes synaptic functions in the hippocampus.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Sci. 2018 Jan ;136(1):42-45. Epub 2017 Dec 20. PMID: 29317180
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Fisetin
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Phenomenon of music-induced opening of the blood-brain barrier in healthy mice.Dec 22, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Biol Sci. 2020 Dec 23 ;287(1941):20202337. Epub 2020 Dec 16. PMID: 33323086
Article Published Date : Dec 22, 2020
Study Type : Animal Study
Additional Links
Therapeutic Actions : Music
Additional Keywords : Blood Brain Barrier
[+]

Polystyrene nanoplastics penetrate across the blood-brain barrier and induce activation of microglia in the brain of mice.Jun 30, 2022

Pubmed Data : Chemosphere. 2022 Jul ;298:134261. Epub 2022 Mar 14. PMID: 35302003
Article Published Date : Jun 30, 2022
Study Type : Animal Study
Additional Links
Diseases : Brain: Microglial Activation, Microplastic Toxicity
Additional Keywords : Blood Brain Barrier
Problem Substances : Polystyrene nanoparticles
[+]

Polystyrene nanoplastics promote the blood-brain barrier dysfunction through autophagy pathway and excessive erythrophagocytosis.Dec 31, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ecotoxicol Environ Saf. 2025 Jan 1 ;289:117471. Epub 2024 Dec 9. PMID: 39657384
Article Published Date : Dec 31, 2024
Study Type : Animal Study
Additional Links
Diseases : Microplastic Toxicity
Additional Keywords : Blood Brain Barrier
Problem Substances : Nano Plastic-and Micro-Particles, Polystyrene nanoparticles
Adverse Pharmacological Actions : Neurotoxic
[+]

Quercetin improves blood-brain barrier dysfunction in rats with cerebral ischemia reperfusion via Wnt signaling pathway.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(8):4683-4695. Epub 2019 Aug 15. PMID: 31497191
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents, Wnt/β-catenin signaling pathway modulation
Additional Keywords : Blood Brain Barrier
[+]

Resveratrol ameliorates the clinical severity of MS through maintaining the BBB integrity in EAE mice.Aug 16, 2016

Pubmed Data : J Neurophysiol. 2016 Aug 17:jn.00510.2016. Epub 2016 Aug 17. PMID: 27535376
Article Published Date : Aug 16, 2016
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Royal jelly has beneficial effects in neurological disorders of postmenopausal women.Mar 21, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Mar 22 ;24(6). Epub 2019 Mar 22. PMID: 30909491
Article Published Date : Mar 21, 2019
Study Type : Animal Study
Additional Links
Substances : Royal Jelly
Diseases : Alzheimer's Disease, Postmenopausal Disorders
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Salvinorin A mitigated blood-brain barrier damage and HBMEC injury after ischemia/reperfusion.Jun 03, 2021

Pubmed Data : Neurochem Int. 2021 Jun 4:105093. Epub 2021 Jun 4. PMID: 34097989
Article Published Date : Jun 03, 2021
Study Type : Animal Study
Additional Links
Substances : Salvia divinorum
Diseases : Stroke: Ischemic
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Sesamin may be a promising potential therapeutic intervention for preventing disruption of the blood brain barrier after traumatic brain injury.Aug 02, 2017

Pubmed Data : Acta Pharmacol Sin. 2017 Aug 3. Epub 2017 Aug 3. PMID: 28770828
Article Published Date : Aug 02, 2017
Study Type : Animal Study
Additional Links
Substances : Sesamin
Diseases : Traumatic Brain Injury
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Tanshinone IIA was thus shown to be effective in the treatment of EAE through preventing the infiltration of immune cells into the CNS.Jan 14, 2016

Pubmed Data : Eur J Pharmacol. 2016 Jan 15 ;771:18-28. Epub 2015 Dec 10. PMID: 26683637
Article Published Date : Jan 14, 2016
Study Type : Animal Study
Additional Links
Substances : Tanshinone IIA
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin.Jun 30, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomaterials. 2020 Jul ;245:119987. Epub 2020 Mar 19. PMID: 32229332
Article Published Date : Jun 30, 2020
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, NF-kappaB Inhibitor
Additional Keywords : Blood Brain Barrier
[+]

Tetramethylpyrazine attenuates blood-brain barrier disruption in ischemia/reperfusion injury through the JAK/STAT signaling pathway.Jul 04, 2019

Pubmed Data : Eur J Pharmacol. 2019 Jul 5 ;854:289-297. Epub 2019 Apr 17. PMID: 31004602
Article Published Date : Jul 04, 2019
Study Type : Animal Study
Additional Links
Substances : Ligustrazine
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

These data demonstrated that ECFC-derived exosomes have beneficial effects on blood-brain barrier integrity in mice with traumatic brain injury.Jun 05, 2018

Pubmed Data : Exp Neurol. 2018 Jun 6 ;307:99-108. Epub 2018 Jun 6. PMID: 29883579
Article Published Date : Jun 05, 2018
Study Type : Animal Study
Additional Links
Diseases : Brain Injury: Traumatic
Additional Keywords : Blood Brain Barrier, Exosomes
[+]

This study support the positive effect of Crocus sativus against Alzheimer's disease by reducing Aβ pathological manifestations.May 14, 2017

Pubmed Data : ACS Chem Neurosci. 2017 May 15. Epub 2017 May 15. PMID: 28471166
Article Published Date : May 14, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Saffron
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Total glucosides of paeony alleviates blood-brain barrier disruption and cerebral ischemia/reperfusion injury.Apr 30, 2020

Pubmed Data : Pharmazie. 2020 May 1 ;75(5):207-211. PMID: 32393431
Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Substances : Peony
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Treadmill exercise ameliorates cognitive impairment and white matter injury from blood-brain barrier disruption induced by cerebral hypoperfusion.Jan 17, 2017

Pubmed Data : Neurosci Lett. 2017 Jan 18 ;638:83-89. Epub 2016 Dec 9. PMID: 27956237
Article Published Date : Jan 17, 2017
Study Type : Animal Study
Additional Links
Diseases : Cerebral Hypoperfusion
Therapeutic Actions : Exercise
Pharmacological Actions : Neuroprotective Agents, Prophylactic Agents
Additional Keywords : Blood Brain Barrier
[+]

Vitamin D deficiency increases blood-brain barrier dysfunction after ischemic stroke in male rats.Nov 27, 2018

Pubmed Data : Exp Neurol. 2018 Nov 28 ;312:63-71. Epub 2018 Nov 28. PMID: 30502340
Article Published Date : Nov 27, 2018
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Stroke: Ischemic, Vitamin D Deficiency
Additional Keywords : Blood Brain Barrier, Risk Factors
[+]

β-caryophyllene liposomes attenuate neurovascular unit damage after subarachnoid hemorrhage.May 21, 2020

Pubmed Data : Neurochem Res. 2020 May 22. Epub 2020 May 22. PMID: 32444923
Article Published Date : May 21, 2020
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Subarachnoid hemorrhage
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Alpha-mangostin potentially possesses neuroprotective effects in a cellular model of Parkinson's disease.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2015 ;2015:919058. Epub 2015 Aug 18. PMID: 26357513
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Mangosteen
Diseases : Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier, Gene Expression Regulation
[+]

A mixture of anthocyanins and anthocyanidins could target multiple mechanisms involved in the etiology of AD and could be useful in preventing and treating AD.Jul 29, 2015

Pubmed Data : Cent Nerv Syst Agents Med Chem. 2015 Jul 30. Epub 2015 Jul 30. PMID: 26238538
Article Published Date : Jul 29, 2015
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins
Diseases : Alzheimer's Disease, Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Anthocyanidins, Blood Brain Barrier
[+]

Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease.May 01, 2019

Pubmed Data : Biochim Biophys Acta Mol Basis Dis. 2019 May 2. Epub 2019 May 2. PMID: 31055081
Article Published Date : May 01, 2019
Study Type : In Vitro Study
Additional Links
Substances : Astaxanthin
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier, Natural Substances Versus Drugs
[+]

Blood-brain barrier disturbances in diabetes-associated dementia: Therapeutic potential for cannabinoids.Jan 03, 2019

Pubmed Data : Pharmacol Res. 2019 Jan 4. Epub 2019 Jan 4. PMID: 30616019
Article Published Date : Jan 03, 2019
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Dementia, Diabetes: Cognitive Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Blood-brain barrier permeability study of ginger constituents.Aug 18, 2019

Pubmed Data : J Pharm Biomed Anal. 2019 Aug 19 ;177:112820. Epub 2019 Aug 19. PMID: 31476432
Article Published Date : Aug 18, 2019
Study Type : In Vitro Study
Additional Links
Substances : 6-Shogaol, Ginger, Gingerol
Diseases : Alzheimer's Disease, Parkinson's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Blood-brain barrier-permeable aporphine-type alkaloids in Nelumbo nucifera flowers with accelerative effects on neurite outgrowth in PC-12 cells.Nov 08, 2019

Pubmed Data : J Nat Med. 2019 Nov 9. Epub 2019 Nov 9. PMID: 31707550
Article Published Date : Nov 08, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lotus
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuritogenic
Additional Keywords : Blood Brain Barrier
[+]

Brain inflammation is both a cause and a result of blood brain barrier dysfunction and has implications in epilepsy, stroke, and Parkinson's disease.Nov 01, 2012

Pubmed Data : Epilepsia. 2012 Nov ;53 Suppl 6:37-44. PMID: 23134494
Article Published Date : Nov 01, 2012
Study Type : Review
Additional Links
Diseases : Brain Inflammation , Epilepsy, Parkinson's Disease, Stroke
Additional Keywords : Blood Brain Barrier
Adverse Pharmacological Actions : Blood Brain Barrier Injury
[+]

Brain targeting with docosahexaenoic acid as a prospective therapy for neurodegenerative diseases Jan 30, 2020

Pubmed Data : Biochimie. 2020 Jan 31. Epub 2020 Jan 31. PMID: 32014503
Article Published Date : Jan 30, 2020
Study Type : Review
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Cannabidiol might be a potent target for modulating the human blood-brain barrier.Feb 04, 2019

Pubmed Data : Mol Pharm. 2019 Feb 5. Epub 2019 Feb 5. PMID: 30721081
Article Published Date : Feb 04, 2019
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol
Additional Keywords : Blood Brain Barrier
[+]

Delivering crocetin across the blood-brain barrier by using γ-cyclodextrin to treat Alzheimer's disease.Feb 26, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 Feb 27 ;10(1):3654. Epub 2020 Feb 27. PMID: 32107408
Article Published Date : Feb 26, 2020
Study Type : In Vitro Study
Additional Links
Substances : Crocetin
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Effects of glyphosate and aminomethylphosphonic acid on an isogeneic model of the human blood-brain barrier.Dec 30, 2018

Pubmed Data : Toxicol Lett. 2018 Dec 31 ;304:39-49. Epub 2018 Dec 31. PMID: 30605748
Article Published Date : Dec 30, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Glyphosate Toxicity
Additional Keywords : Blood Brain Barrier
Problem Substances : Glyphosate
[+]

Electroconvulsive therapy, hypertensive surge, blood-brain barrier breach, and amnesia.May 31, 2014

Pubmed Data : J ECT. 2014 Jun ;30(2):160-4. PMID: 24800688
Article Published Date : May 31, 2014
Study Type : Review
Additional Links
Diseases : Amnesia, Hypertension, Memory Disorders
Additional Keywords : Blood Brain Barrier
Anti Therapeutic Actions : Electroconvulsive Therapy
[+]

Incorporation of docosahexaenoic acid (DHA) enhances nanodelivery of antiretroviral across the blood-brain barrier for treatment of HIV reservoir in brain.Sep 29, 2020

Pubmed Data : J Control Release. 2020 Sep 30. Epub 2020 Sep 30. PMID: 33010335
Article Published Date : Sep 29, 2020
Study Type : In Vitro Study
Additional Links
Substances : DHA (Docosahexaenoic Acid)
Diseases : HIV Infections
Additional Keywords : Blood Brain Barrier
[+]

Macrophage exosomes as natural nanocarriers for protein delivery to inflamed brain.Jul 09, 2017

Pubmed Data : Biomaterials. 2017 Jul 10 ;142:1-12. Epub 2017 Jul 10. PMID: 28715655
Article Published Date : Jul 09, 2017
Study Type : In Vitro Study
Additional Links
Diseases : Brain Inflammation , Central Nervous System Diseases
Additional Keywords : Blood Brain Barrier, Exosomes
[+]

Melatonin has protective effects against acute IL-1β-induced blood brain barrier dysfunction and hyperpermeability.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2016 ;11(5):e0154427. Epub 2016 May 6. PMID: 27152411
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Brain Edema, Brain Injury: Traumatic
Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Blood Brain Barrier
[+]

Melatonin protects blood-brain barrier integrity and permeability.Dec 06, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2019 Dec 7 ;11. Epub 2019 Dec 7. PMID: 31811815
Article Published Date : Dec 06, 2019
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Pharmacological Actions : Matrix metalloproteinase-9 (MMP-9) inhibitor, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Microwave radiation may damage the blood brain barrier, according to this in vitro study.Aug 01, 2015

Pubmed Data : Mol Neurobiol. 2015 Aug ;52(1):478-91. Epub 2014 Sep 9. PMID: 25195697
Article Published Date : Aug 01, 2015
Study Type : In Vitro Study
Additional Links
Additional Keywords : Blood Brain Barrier, Brain Function, EMF
Anti Therapeutic Actions : Electromagnetic Field Harms, Electromagnetic Radiation, Microwave Radiation, Mobile Phone Radiation
Problem Substances : Cell Phone Exposure
Adverse Pharmacological Actions : Blood Brain Barrier Injury
[+]

Myricetin oligomer triggers multi-receptor mediated penetration and autophagic restoration of blood-brain barrier for ischemic stroke treatment.Apr 08, 2024

Pubmed Data : ACS Nano. 2024 Apr 9 ;18(14):9895-9916. Epub 2024 Mar 27. PMID: 38533773
Article Published Date : Apr 08, 2024
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids
Diseases : Stroke: Ischemic
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Nattokinase as a potential therapeutic agent for preventing blood-brain barrier dysfunction in neurodegenerative disorders.Nov 25, 2024

Pubmed Data : Brain Res. 2024 Nov 26 ;1849:149352. Epub 2024 Nov 26. PMID: 39592088
Article Published Date : Nov 25, 2024
Study Type : Review
Additional Links
Diseases : Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Natural xanthones have multifunctional activities against Alzheimer's disease. Jun 30, 2016

Pubmed Data : Neurochem Res. 2016 Jul ;41(7):1806-17. Epub 2016 Apr 2. PMID: 27038926
Article Published Date : Jun 30, 2016
Study Type : In Vitro Study
Additional Links
Substances : Mangosteen, Xanthones
Diseases : Alzheimer's Disease
Pharmacological Actions : Antioxidants, Heme oxygenase-1 inducer, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Neuroprotective effects of a biodegradable poly(lactic-co-glycolic acid)-ginsenoside Rg3 nanoformulation.Dec 31, 2017

Pubmed Data : J Drug Target. 2018 02 ;26(2):182-193. Epub 2017 Jul 17. PMID: 28697660
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Polysorbate-80 damages the blood brain barrier and facilitates the entry of potentially neurotoxic compounds into the brain.Jan 01, 2005

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : NeuroRx. 2005 Jan ;2(1):3-14. PMID: 15717053
Article Published Date : Jan 01, 2005
Study Type : Review
Additional Links
Additional Keywords : Blood Brain Barrier, Vaccine Research
Problem Substances : Polysorbate 80
Adverse Pharmacological Actions : Blood Brain Barrier Injury, Neurotoxic
[+]

Preventive and therapeutic effects of Punica granatum polyphenols in neurological conditions.Jan 16, 2023

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2023 Jan 17 ;24(3). Epub 2023 Jan 17. PMID: 36768185
Article Published Date : Jan 16, 2023
Study Type : Review
Additional Links
Substances : Pomegranate
Diseases : Anxiety, Depression, Neurodegenerative Diseases
Pharmacological Actions : Anti-Anxiety Agents, Anti-Apoptotic, Antidepressive Agents, Antioxidants, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Prolonged morphine exposure may result in increased cell migration into the central nervous system.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 ;17(6). Epub 2016 Jun 9. PMID: 27294916
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Additional Keywords : Blood Brain Barrier, Risk Factors
Problem Substances : Morphine
[+]

Rooibos tea could profoundly alter the redox status of brain endothelial cells. Jan 09, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Alcohol Clin Exp Res. 2020 10 ;44(10):1997-2007. Epub 2020 Sep 20. PMID: 32780433
Article Published Date : Jan 09, 2020
Study Type : In Vitro Study
Additional Links
Substances : Rooibos
Diseases : Alcohol Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

Rutin could be used as a natural therapy for Alzheimer's disease.Feb 16, 2016

Pubmed Data : Curr Med Chem. 2016 Feb 17. Epub 2016 Feb 17. PMID: 26898570
Article Published Date : Feb 16, 2016
Study Type : Review
Additional Links
Substances : Rutin
Diseases : Alzheimer's Disease, Neurodegenerative Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Chelating Agents
Additional Keywords : Blood Brain Barrier
[+]

These findings will aid in the optimization of naringenin and improve its neurotherapeutic activities in the treatment of Alzheimer's disease.Jun 30, 2018

Pubmed Data : Comput Biol Med. 2018 Jul 1 ;98:168-177. Epub 2018 May 16. PMID: 29860210
Article Published Date : Jun 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Naringenin
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Blood Brain Barrier
[+]

This review focuses on the roles and mechanisms of action of different adjuvants which lead to the autoimmune/inflammatory response that leads to the autoimmune syndrome induced by adjuvants (ASIA).Dec 01, 2013

Pubmed Data : J Autoimmun. 2013 Dec ;47:1-16. Epub 2013 Nov 13. PMID: 24238833
Article Published Date : Dec 01, 2013
Study Type : Review
Additional Links
Diseases : Autoimmune Diseases, Autoimmune Syndrome Induced by Adjuvants (ASIA), Inflammation
Additional Keywords : Blood Brain Barrier, Iatrogenic Disease
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
Adverse Pharmacological Actions : Inflammatory
[+]

Thymoquinone suppresses growth and invasion and induces apoptosis of glial tumor cells.Jul 22, 2016

Pubmed Data : Biomed Pharmacother. 2016 Jul 23 ;83:635-640. Epub 2016 Jul 23. PMID: 27459120
Article Published Date : Jul 22, 2016
Study Type : Review
Additional Links
Substances : Thymoquinone
Diseases : Glial Cell Tumors, Glioblastoma, Neurodegenerative Diseases
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Autophagy Inhibitors, Telomerase Inhibitor
Additional Keywords : Blood Brain Barrier

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