Cannabinoid Receptors

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48 Diseases Researched for Cannabinoid Receptors
NameACCKFocus
Breast Cancer49Locked
Glioblastoma38Locked
Cardiovascular Diseases15Locked
Colorectal Cancer15Locked
Inflammation45Locked
Skin Cancer35Locked
Cancers: All44Locked
Cancer Metastasis23Locked
Colon Cancer23Locked
Endocannabinoid System33Locked
Thyroid Cancer23Locked
Acute lymphoblastic leukemia (ALL)12Locked
Aging12Locked
Alcohol Withdrawal12Locked
Bladder Cancer12Locked
Breast Cancer: Metastatic12Locked
Carcinoma: Non-Small-Cell Lung12Locked
Cerebral Ischemia12Locked
Diabetes Mellitus: Type 212Locked
Lung Cancer12Locked
Lymphoma22Locked
Melanoma12Locked
Osteoporosis12Locked
Oxidative Stress12Locked
Prostate Cancer22Locked
Acne11Locked
Acute T cell Leukemias11Locked
Allergies11Locked
Astrocytoma11Locked
Breast Cancer: HER-2 Overexpressed11Locked
Burkitt Lymphoma11Locked
Dermatitis11Locked
Dry Skin 11Locked
Gastrointestinal Diseases11Locked
Gastrointestinal Inflammation11Locked
Glioma11Locked
HIV Infections11Locked
Hepatitis C11Locked
Herpes Simplex Virus Type 211Locked
Immune Disorders11Locked
Inflammatory Bowel Diseases11Locked
Influenza11Locked
Leukemia11Locked
Lymphoma: Non-Hodgkin11Locked
Prostate: PSA Doubling11Locked
Psoriasis11Locked
Seborrheic Keratosis11Locked
Urinary Bladder Diseases11Locked
8 Substances Researched for Cannabinoid Receptors
NameACCKFocus
Cannabinoids 2030Locked
Endocannabinoids712Locked
Cannabidiol 510Locked
Delta-tetrahydrocannabinol (THC)610Locked
Anandamide49Locked
Cannabinoids: Synthetic59Locked
Black Raspberry12Locked
Olive Oil12Locked
1 Therapeutic Actions Researched for Cannabinoid Receptors
NameACCKFocus
Electroacupuncture35Locked
35 Pharmacological Actions Researched for Cannabinoid Receptors
NameACCKFocus
Antiproliferative 1729Locked
Apoptotic1623Locked
Anti-metastatic711Locked
Antineoplastic Agents47Locked
Angiogenesis Inhibitors35Locked
Cell cycle arrest35Locked
Vasodilator Agents15Locked
Anti-Inflammatory Agents44Locked
Anticarcinogenic Agents33Locked
Cannabinoid Receptor Antagonist/Inverse Agonist23Locked
Anti-Apoptotic12Locked
Anti-Tumor12Locked
Catalase Up-Regulation12Locked
Chemopreventive12Locked
Chemosensitizer12Locked
Chemotherapeutic12Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor12Locked
Neuroprotective Agents12Locked
STAT3 Activation12Locked
Superoxide Dismutase Up-regulation12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
Vascular Endothelial Growth Factor A Inhibitor12Locked
Vascular Endothelial Growth Factor Regulator12Locked
Analgesics11Locked
Anti-Androgen11Locked
Anti-Angiogenic11Locked
Antinoceceptive 11Locked
Caspase-3 Activation11Locked
Caspase-8 activation11Locked
Caspase-9 Activation11Locked
Immunomodulatory11Locked
Immunosuppressive Agents11Locked
NADPH Oxidase Inhibitors11Locked
P21 Activation11Locked
Tumor Suppressor Protein p53 Upregulation11Locked

View the Evidence:
53 Abstracts with Cannabinoid Receptors Research

[+]

Anandamide is a potent and selective inhibitor of the proliferation of breast cancer cells.Jul 06, 1998

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 1998 Jul 7 ;95(14):8375-80. PMID: 9653194
Article Published Date : Jul 06, 1998
Study Type : Human In Vitro
Additional Links
Substances : Anandamide, Cannabinoids
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Cannabinoid Receptors, Dose Response
[+]

Cannabidiol causes vasorelaxation of the human mesenteric artery.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cardiovasc Res. 2015 Sep 1 ;107(4):568-78. Epub 2015 Jun 19. PMID: 26092099
Article Published Date : Aug 31, 2015
Study Type : Human In Vitro
Additional Links
Substances : Cannabidiol
Diseases : Cardiovascular Diseases
Pharmacological Actions : Vasodilator Agents
Additional Keywords : Cannabinoid Receptors
[+]

Elevated CB2 receptor expression was identified in glioblastoma cells.Jun 29, 2009

Pubmed Data : Brain Res Bull. 2009 Jun 30 ;79(5):333-7. Epub 2009 Feb 6. PMID: 19480992
Article Published Date : Jun 29, 2009
Study Type : Human In Vitro
Additional Links
Diseases : Glioblastoma
Additional Keywords : Cannabinoid Receptors
[+]

Endocannabinoid and ceramide levels are altered in patients with colorectal cancer.Jun 30, 2015

Pubmed Data : Oncol Rep. 2015 Jul ;34(1):447-54. Epub 2015 May 12. PMID: 25975960
Article Published Date : Jun 30, 2015
Study Type : Human In Vitro
Additional Links
Substances : Endocannabinoids
Diseases : Colorectal Cancer
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System
[+]

A chronic low dose of Δ9-tetrahydrocannabinol (THC) restores cognitive function in old mice.May 07, 2017

Pubmed Data : Nat Med. 2017 May 8. Epub 2017 May 8. PMID: 28481360
Article Published Date : May 07, 2017
Study Type : Animal Study
Additional Links
Substances : Delta-tetrahydrocannabinol (THC)
Diseases : Aging: Brain , Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Cannabinoid Receptors
[+]

A synthetic cannabinoid inhibited CXCL12-induced migration and invasive properties of breast cancer cells.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2011 ;6(9):e23901. Epub 2011 Sep 7. PMID: 21915267
Article Published Date : Dec 31, 2010
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabinoids
Diseases : Breast Cancer, Breast Cancer: Metastatic
Pharmacological Actions : Anti-metastatic, Antiproliferative
Additional Keywords : Cannabinoid Receptors, Synthetic Cannabinoids
[+]

Activation of cannabinoid receptors could be a new therapeutic approach for the treatment of skin tumors.Dec 31, 2002

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Invest. 2003 Jan ;111(1):43-50. PMID: 12511587
Article Published Date : Dec 31, 2002
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabinoids
Diseases : Skin Cancer
Pharmacological Actions : Angiogenesis Inhibitors, Antineoplastic Agents, Apoptotic, Vascular Endothelial Growth Factor A Inhibitor, Vascular Endothelial Growth Factor Regulator
Additional Keywords : Cannabinoid Receptors
[+]

Beta-caryophyllene constitutes an alluring therapeutic molecule towards the treatment of multiple sclerosis.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2017 Apr 1 ;18(4). Epub 2017 Apr 1. PMID: 28368293
Article Published Date : Mar 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Inflammation: Brain, Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Additional Keywords : Cannabinoid Receptors
[+]

Beta-caryophyllene could be useful for prevention and treatment of antiretroviral-induced neuropathic pain.Dec 26, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Dec 27 ;25(1). Epub 2019 Dec 27. PMID: 31892132
Article Published Date : Dec 26, 2019
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : HIV Infections, Neuropathic Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Cannabinoid Receptors
[+]

Black raspberry extracts may benefit osteoporotic patients with prostatic disease by simultaneously altering the activation of osteoblasts and osteoclasts.May 31, 2015

Pubmed Data : Aging Male. 2015 Jun ;18(2):124-32. Epub 2014 Aug 19. PMID: 25136745
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Black Raspberry
Diseases : Aging, Osteoporosis
Additional Keywords : Cannabinoid Receptors, Plant Extracts
[+]

Cannabidiol enhanced the ability of THC to inhibit cell proliferation, induce cell cycle arrest and apoptosis.Dec 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Cancer Ther. 2010 Jan ;9(1):180-9. Epub 2010 Jan 6. PMID: 20053780
Article Published Date : Dec 31, 2009
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabidiol, Delta-tetrahydrocannabinol (THC)
Diseases : Cancer Metastasis, Glioblastoma
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Cannabinoid Receptors, Natural Substance Synergy
[+]

Cannabinoids inhibit the growth of melanoma cells but not of normal melanocytes.Nov 30, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : FASEB J. 2006 Dec ;20(14):2633-5. Epub 2006 Oct 25. PMID: 17065222
Article Published Date : Nov 30, 2006
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabinoids , Cannabinoids: Synthetic
Diseases : Melanoma
Pharmacological Actions : Angiogenesis Inhibitors, Anti-metastatic, Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, Chemotherapeutic
Additional Keywords : Cannabinoid Receptors, Selective Cytotoxicity
[+]

Cannabinoids were effective in reducing the tumor load, prolonging the mean survival time as well as curing a significant proportion of mice in this study.Jul 14, 2002

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Blood. 2002 Jul 15 ;100(2):627-34. PMID: 12091357
Article Published Date : Jul 14, 2002
Study Type : Animal Study
Additional Links
Substances : Anandamide, Cannabinoids: Synthetic, Delta-tetrahydrocannabinol (THC)
Diseases : Acute lymphoblastic leukemia (ALL)
Pharmacological Actions : Anti-Tumor, Antineoplastic Agents, Antiproliferative , Apoptotic
Additional Keywords : Cannabinoid Receptors, Significant Treatment Outcome
[+]

Chronic exercise modulates the cellular immunity and its cannabinoid receptors expression.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2019 ;14(11):e0220542. Epub 2019 Nov 18. PMID: 31738771
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Therapeutic Actions : Exercise
Pharmacological Actions : Immunomodulatory
Additional Keywords : Cannabinoid Receptors
[+]

Electroacupuncture inhibits CB1 upregulation induced by ethanol withdrawal in mice.Jun 30, 2012

Pubmed Data : Neurochem Int. 2012 Jul ;61(2):277-85. Epub 2012 May 18. PMID: 22613131
Article Published Date : Jun 30, 2012
Study Type : Animal Study
Additional Links
Diseases : Alcohol Withdrawal
Therapeutic Actions : Electroacupuncture
Additional Keywords : Cannabinoid Receptors
[+]

Electroacupuncture potentiates cannabinoid receptor-mediated descending inhibitory control in a mouse model of knee osteoarthritis.Dec 31, 2017

Pubmed Data : Front Mol Neurosci. 2018 ;11:112. Epub 2018 Apr 6. PMID: 29681797
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Osteoarthritis: Knee
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Antinoceceptive
Additional Keywords : Cannabinoid Receptors
[+]

Electroacupuncture pretreatment enhances STAT3 activation via CB1R to protect against cerebral ischemia.Sep 04, 2013

Pubmed Data : Brain Res. 2013 Sep 5 ;1529:154-64. Epub 2013 Jul 20. PMID: 23880371
Article Published Date : Sep 04, 2013
Study Type : Animal Study
Additional Links
Diseases : Cerebral Ischemia
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents, STAT3 Activation
Additional Keywords : Cannabinoid Receptors
[+]

Extravirgin olive oil up-regulates CB₁ tumor suppressor gene in human colon cancer cells.Feb 28, 2015

Pubmed Data : J Nutr Biochem. 2015 Mar ;26(3):250-8. Epub 2014 Dec 3. PMID: 25533906
Article Published Date : Feb 28, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Olive Oil
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System, Epigenetic Modification In Cancer, Plant Extracts
[+]

Paeoniflorin exerts a neuroprotective effect in model of dementia.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Med. 2018 ;13:14. Epub 2018 Mar 20. PMID: 29560022
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Paeoniflorin
Diseases : Dementia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Cannabinoid Receptors
[+]

Palmitoylethanolamide attenuates PTZ-induced seizures through CB1 and CB2 receptors.Oct 31, 2015

Pubmed Data : Epilepsy Res. 2015 Nov ;117:23-8. Epub 2015 Aug 14. PMID: 26370914
Article Published Date : Oct 31, 2015
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Seizures
Pharmacological Actions : Anticonvulsants
Additional Keywords : Cannabinoid Receptors
[+]

Palmitoylethanolamide improves murine experimental colitis.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2015 Jan ;172(1):142-58. Epub 2014 Dec 1. PMID: 25205418
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Cannabinoid Receptors
[+]

Synthetic cannabinoids inhibited growth, migration and invasion of NSCLC cells in in vitro as well as in vivo in a mouse model.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Prev Res (Phila). 2011 Jan ;4(1):65-75. Epub 2010 Nov 19. PMID: 21097714
Article Published Date : Dec 31, 2010
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabinoids: Synthetic
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Cannabinoid Receptors
[+]

THC may provide a protective effect against oxidative damage induced by diabetes.Sep 30, 2014

Pubmed Data : Cell Biochem Funct. 2014 Oct ;32(7):612-9. Epub 2014 Sep 3. PMID: 25187240
Article Published Date : Sep 30, 2014
Study Type : Animal Study
Additional Links
Substances : Delta-tetrahydrocannabinol (THC)
Diseases : Diabetes Mellitus: Type 2, Oxidative Stress
Pharmacological Actions : Catalase Up-Regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Cannabinoid Receptors
[+]

The discovery of IL-12-induced CB2 overexpression in thyroid cancer cells may offer a new target for anaplastic thyroid cancer treatmentJan 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Gene Ther. 2008 Feb ;15(2):101-7. Epub 2007 Dec 21. PMID: 18197164
Article Published Date : Jan 31, 2008
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabinoids , Cannabinoids: Synthetic
Diseases : Thyroid Cancer
Pharmacological Actions : Apoptotic, Cannabinoid Receptor Antagonist/Inverse Agonist, Chemosensitizer
Additional Keywords : Cannabinoid Receptors, Chemothapeutic Synergy: Paclitaxel
[+]

The in vivo assessment of the role of CB receptors in inflammation and cancer might be instrumental in broadening the understanding about bladder cancer biology.Sep 30, 2015

Pubmed Data : Life Sci. 2015 Oct 1 ;138:41-51. Epub 2014 Oct 15. PMID: 25445433
Article Published Date : Sep 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Bladder Cancer, Inflammation
Pharmacological Actions : Antiproliferative , Apoptotic, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Cannabinoid Receptors
[+]

These results confirm the value of exogenous cannabinoids for the treatment of melanomas. Sep 30, 2015

Pubmed Data : Life Sci. 2015 Oct 1 ;138:35-40. Epub 2015 Apr 25. PMID: 25921771
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)
Diseases : Skin Cancer
Pharmacological Actions : Antiproliferative
Additional Keywords : Cannabinoid Receptors
[+]

β-Caryophyllene, a natural bicyclic sesquiterpene attenuates doxorubicin-induced cardiotoxicity.Mar 01, 2019

Pubmed Data : Chem Biol Interact. 2019 Mar 2. Epub 2019 Mar 2. PMID: 30836069
Article Published Date : Mar 01, 2019
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Chemoprotective Agents
Additional Keywords : Cannabinoid Receptors
[+]

Δ9-tetrahydrocannabinol prevents mortality from acute respiratory distress syndrome.Aug 27, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Aug 28 ;21(17). Epub 2020 Aug 28. PMID: 32872332
Article Published Date : Aug 27, 2020
Study Type : Animal Study
Additional Links
Substances : Delta-tetrahydrocannabinol (THC)
Diseases : Acute Respiratory Distress Syndrome
Pharmacological Actions : MicroRNA modulator
Additional Keywords : Cannabinoid Receptors, Cytokine Modulation, Cytokine Storm
[+]

An analogue of anandamide Met-F-AEA could have significance in providing a basis for the management of thyroid carcinomas.Mar 31, 2010

Pubmed Data : Invest New Drugs. 2010 Apr ;28(2):115-23. Epub 2009 Feb 3. PMID: 19189054
Article Published Date : Mar 31, 2010
Study Type : In Vitro Study
Additional Links
Diseases : Thyroid Cancer
Pharmacological Actions : Antiproliferative , Apoptotic, P21 Activation, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Cannabinoid Receptors
[+]

Beta-caryophyllene administration could be a novel treatment to reduce hyper-inflammation in human sepsis.Dec 31, 2017

Pubmed Data : Med Hypotheses. 2018 Jan ;110:68-70. Epub 2017 Nov 4. PMID: 29317072
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Substances : Beta-Caryophyllene
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Cannabinoid Receptors
[+]

Cannabinoid receptor ligands induce decreased viability, growth suppression and cell death by apoptosis in MCL cells.Dec 18, 2005

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : FEBS Lett. 2005 Dec 19 ;579(30):6885-9. PMID: 16337199
Article Published Date : Dec 18, 2005
Study Type : In Vitro Study
Additional Links
Substances : Anandamide, Cannabinoids , Cannabinoids: Synthetic
Diseases : Breast Cancer, Lymphoma
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Cannabinoid Receptors
[+]

Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors.Nov 22, 1999

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 1999 Nov 23 ;96(24):14136-41. PMID: 10570211
Article Published Date : Nov 22, 1999
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol, Cannabinoids
Diseases : Endothelial Dysfunction
Pharmacological Actions : Vasodilator Agents
Additional Keywords : Cannabinoid Receptors
[+]

Cannabinoids - via direct or indirect activation of CB(1) and/or CB(2) receptors exert protective effects in well-established models of intestinal inflammation and colon cancer.Jul 31, 2009

Pubmed Data : Pharmacol Res. 2009 Aug ;60(2):117-25. Epub 2009 Mar 18. PMID: 19442536
Article Published Date : Jul 31, 2009
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Colon Cancer, Endocannabinoid System, Gastrointestinal Inflammation, Inflammation, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents
Additional Keywords : Cannabinoid Receptors
[+]

Cannabinoids are promising candidates for gastrointestinal and urinary diseases.Dec 31, 2014

Pubmed Data : Handb Exp Pharmacol. 2015 ;231:423-47. PMID: 26408170
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Cannabidiol, Cannabinoids
Diseases : Gastrointestinal Diseases, Urinary Bladder Diseases
Additional Keywords : Cannabinoid Receptors
[+]

Cannabinoids exert anti-inflammatory, anti-proliferative, anti-invasive, anti-metastatic and pro-apoptotic effects in different cancer types.May 31, 2015

Pubmed Data : Histol Histopathol. 2015 Jun ;30(6):629-45. Epub 2014 Dec 4. PMID: 25472761
Article Published Date : May 31, 2015
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Glioma
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative , Apoptotic
Additional Keywords : Cannabinoid Receptors
[+]

Cannabinoids have the potential to regulate the activation and balance of human Th1/Th2 cells by a CB2 receptor-dependent pathway.Nov 30, 2002

Pubmed Data : J Neuroimmunol. 2002 Dec ;133(1-2):124-31. PMID: 12446015
Article Published Date : Nov 30, 2002
Study Type : In Vitro Study
Additional Links
Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)
Diseases : Immune Dysregulation: TH1/TH2 imbalance
Pharmacological Actions : Immunomodulatory
Additional Keywords : Cannabinoid Receptors
[+]

Cannabinoids might be a suitable treatment for rheumatoid arthritis.Apr 30, 2019

Pubmed Data : Curr Opin Rheumatol. 2019 May ;31(3):271-278. PMID: 30920973
Article Published Date : Apr 30, 2019
Study Type : Review
Additional Links
Substances : Cannabidiol
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Cannabinoid Receptors
[+]

Cannabinoids modulate neuronal activity and cancer by CB1 and CB2 receptor-independent mechanisms.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2017 ;8:720. Epub 2017 Oct 10. PMID: 29066974
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Cancers: All
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Cannabinoid Receptors
[+]

Cannabinoids possess attributes that have impact in both cancer pain and prostate cancer pathophysiology.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Urol. 2012 Jan ;28(1):9-14. PMID: 22557710
Article Published Date : Dec 31, 2011
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Prostate: PSA Doubling, Prostate Cancer
Pharmacological Actions : Analgesics, Anti-Angiogenic
Additional Keywords : Cannabinoid Receptors
[+]

Cannabinoids prevent proliferation and cause apoptosis via a combination of cannabinoid receptor-independent, cellular and molecular mechanisms.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2013 Jan ;168(1):79-102. PMID: 22594963
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol, Cannabinoids
Diseases : Prostate Cancer
Pharmacological Actions : Anti-Androgen, Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Cannabinoid Receptors
[+]

CB1 receptor immunoreactivity was significantly lower while CB2 receptor immunoreactivity was significantly greater in the membranes of glioblastoma multiforme and astrocytoma.Apr 30, 2010

Pubmed Data : Neurochem Int. 2010 May-Jun;56(6-7):829-33. Epub 2010 Mar 20. PMID: 20307616
Article Published Date : Apr 30, 2010
Study Type : In Vitro Study
Additional Links
Substances : Cannabinoids
Diseases : Astrocytoma, Glioblastoma
Additional Keywords : Cannabinoid Receptors
[+]

CB2 receptor activation signals apoptosis via a ceramide-dependent stimulation of the mitochondrial intrinsic pathway.Jun 30, 2006

Pubmed Data : Exp Cell Res. 2006 Jul 1 ;312(11):2121-31. Epub 2006 Apr 19. PMID: 16624285
Article Published Date : Jun 30, 2006
Study Type : In Vitro Study
Additional Links
Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)
Diseases : Acute T cell Leukemias
Pharmacological Actions : Apoptotic
Additional Keywords : Cannabinoid Receptors
[+]

Electroacupuncture increases the CB2 receptor expression on keratinocytes and infiltrating inflammatory cells in inflammatory skin tissues.Nov 30, 2010

Pubmed Data : J Pain. 2010 Dec ;11(12):1250-8. Epub 2010 Jun 2. PMID: 20627823
Article Published Date : Nov 30, 2010
Study Type : In Vitro Study
Additional Links
Diseases : Inflammation
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Antinoceceptive
Additional Keywords : Cannabinoid Receptors
[+]

In the current study we demonstrated that cannabidiol can induce apoptosis in murine as well as human leukemia cells.Aug 31, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Pharmacol. 2006 Sep ;70(3):897-908. Epub 2006 Jun 5. PMID: 16754784
Article Published Date : Aug 31, 2006
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol
Diseases : Leukemia
Pharmacological Actions : Apoptotic, Caspase-3 Activation, Caspase-8 activation, Caspase-9 Activation, NADPH Oxidase Inhibitors
Additional Keywords : Cannabinoid Receptors
[+]

The endocannabinoid system controls the growth and metastasis of malignant cells.Apr 30, 2003

Pubmed Data : Recenti Prog Med. 2003 May ;94(5):194-8. PMID: 12723496
Article Published Date : Apr 30, 2003
Study Type : Review
Additional Links
Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC), Endocannabinoids
Diseases : Cancer Metastasis, Cancers: All, Endocannabinoid System
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic
Additional Keywords : Cannabinoid Receptors
[+]

The experimental evidence reviewed in this article argues in favor of the therapeutic potential of these compounds in immune disorders and cancer.Jan 31, 2002

Pubmed Data : Prostaglandins Leukot Essent Fatty Acids. 2002 Feb-Mar;66(2-3):319-32. PMID: 12052046
Article Published Date : Jan 31, 2002
Study Type : Review
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Cancers: All, Endocannabinoid System, Immune Disorders
Pharmacological Actions : Antiproliferative , Apoptotic, Immunosuppressive Agents
Additional Keywords : Cannabinoid Receptors
[+]

The present study reviews current insights into the role of cannabinoids and their receptors on viral infections.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Virol. 2016 Jan ;88(1):1-12. Epub 2015 Jun 25. PMID: 26059175
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Hepatitis C, Herpes Simplex Virus Type 2, HIV Infections, Influenza
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory
Additional Keywords : Cannabinoid Receptors
[+]

These results show an association between elevated CB2 expression in HER2+ breast tumors and poor patient prognosis.May 31, 2015

Pubmed Data : J Natl Cancer Inst. 2015 Jun ;107(6):djv077. Epub 2015 Apr 8. PMID: 25855725
Article Published Date : May 31, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Breast Cancer, Breast Cancer: HER-2 Overexpressed
Additional Keywords : Cannabinoid Receptors
[+]

This review critically discusses the pharmacology of CB receptor activation as a novel therapeutic anticancer strategyJun 30, 2009

Pubmed Data : J Pharm Pharmacol. 2009 Jul ;61(7):839-53. PMID: 19589225
Article Published Date : Jun 30, 2009
Study Type : Review
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Cancers: All
Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Anticarcinogenic Agents, Antineoplastic Agents, Antiproliferative
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System
[+]

This review discusses how the endocannabinoid system can help treat diseases of the skin.Jul 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Trends Pharmacol Sci. 2009 Aug ;30(8):411-20. Epub 2009 Jul 14. PMID: 19608284
Article Published Date : Jul 31, 2009
Study Type : Review
Additional Links
Substances : Endocannabinoids
Diseases : Acne, Allergies, Dermatitis, Dry Skin , Inflammation, Psoriasis, Seborrheic Keratosis, Skin Cancer
Pharmacological Actions : Anticarcinogenic Agents, Cannabinoid Receptor Antagonist/Inverse Agonist
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System
[+]

This review summarises the demonstrated antitumour actions of cannabinoids and indicating possible avenues for cannabinoids as antitumour agents.Nov 30, 2003

Pubmed Data : Expert Opin Ther Targets. 2003 Dec ;7(6):749-58. PMID: 14640910
Article Published Date : Nov 30, 2003
Study Type : Review
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Cancers: All
Additional Keywords : Cannabinoid Receptors
[+]

Using cannabinoid receptor ligands will have efficiency in reducing tumor burden in malignant lymphoma overexpressing CB1 and CB2.Aug 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Cancer. 2008 Sep 1 ;123(5):1025-33. PMID: 18546271
Article Published Date : Aug 31, 2008
Study Type : In Vitro Study
Additional Links
Substances : Anandamide
Diseases : Burkitt Lymphoma, Lymphoma, Lymphoma: Non-Hodgkin
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Cannabinoid Receptors
[+]

ω-3 endocannabinoid epoxides have anti-inflammatory effects. Jul 06, 2017

Pubmed Data : Proc Natl Acad Sci U S A. 2017 Jul 7. Epub 2017 Jul 7. PMID: 28687674
Article Published Date : Jul 06, 2017
Study Type : In Vitro Study
Additional Links
Substances : Polyunsaturated Fatty Acids (PUFAs)
Diseases : Brain Inflammation , Inflammation
Pharmacological Actions : Anti-Angiogenic, Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-6 Downregulation
Additional Keywords : Cannabinoid Receptors, Dose Response, Endocannabinoid Epoxides

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