Circadian Rhythm

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2 Problem Substances Researched for Circadian Rhythm

Name	AC	CK	Focus
Aspirin	1	10
Cell Phone Exposure	1	1

21 Diseases Researched for Circadian Rhythm

Name	AC	CK
Circadian Dysregulation	8	30
Sleep Disorders	6	27
Computer display light exposure	1	10
Mood Disorders	1	10
Traumatic Brain Injury	1	10
Obesity	2	4
Anxiety	1	2
Blue Light Toxicity	1	2
Cancers: All	1	2
Depression	1	2
Diabetes Mellitus: Type 2	1	2
High Fat Diet	1	2
Metabolic Diseases	1	2
Nonalcoholic fatty liver disease (NAFLD)	1	2
Oxidative Stress	1	2
Substance Abuse	1	2
Autism Spectrum Disorders	1	1
Electrosensitivity	1	1
Fragile X Syndrome	1	1
Glioma	1	1
Multiple Chemical Sensitivity	1	1

8 Problematic Actions Researched for Circadian Rhythm

Name	AC	CK
Electromagnetic Field Harms	3	12
Electromagnetic Radiation	3	12
Blue Light (400−495 nm)	1	2
Electroconvulsive Therapy	1	2
Laptop Computer Use	1	1
Microwave Radiation	1	1
Mobile Phone Radiation	1	1
Wi-Fi Radiation	1	1

2 Adverse Pharmacological Actions Researched for Circadian Rhythm

Name	AC	CK	Focus
Endocrine Disruptor	1	1
Melatonin Interference	1	1

8 Substances Researched for Circadian Rhythm

Name	AC	CK
Melatonin	4	15
Nobiletin	2	4
Pterostilbene	1	2
Taurine	1	2
Turmeric	1	2
Curcumin	1	1
Curcuminoids	1	1
Pomegranate	1	1

5 Therapeutic Actions Researched for Circadian Rhythm

Name	AC	CK
Sunlight exposure	2	20
Light Therapy	1	10
Light-Emitting Diodes (LEDs) Therapy	1	10
Exercise	2	4
Dietary Modification: Low Carbohydrate/Ketogenic	1	1

7 Pharmacological Actions Researched for Circadian Rhythm

Name	AC	CK
PER2 Protein Expression Up-regulation	1	10
Anti-Anxiety Agents	1	2
Antidepressive Agents	1	2
Antioxidants	1	2
Hepatoprotective	1	2
Nrf2 activation	1	2
Apoptotic	1	1

Research Articles 24
Cumulative Knowledge Score 38
Overall Research Rating GOOD

View the Evidence:
24 Abstracts with Circadian Rhythm Research

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View the Evidence: 24 Abstracts with Circadian Rhythm Research

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Access to daylight at home improves circadian alignment, sleep, and mental health in healthy adults.Sep 22, 2021

Evening exposure to a light-emitting diodes (LED)-backlit computer screen affects circadian physiology and cognitive performance.Apr 30, 2011

Evening exposure to blue light stimulates the expression of the clock gene PER2 in humans.Jan 31, 2006

From dawn to dusk-mimicking natural daylight exposure improves circadian rhythm entrainment in patients with severe brain injury.Jul 10, 2022

Low daytime light exposure is an important environmental risk factor for mood, sleep, and circadian-related outcomes.Nov 30, 2021

The severity of gastric mucosal injury produced by aspirin was significantly greater in the morning compared to the evening.Dec 31, 1986

This study provides evidence that human circadian rhythm can be altered by electromagnetic fields.Jan 01, 1970

Daytime exposure to blue light alters cardiovascular circadian rhythms, electrolyte excretion and melatonin production.Mar 13, 2022

Electroconvulsive seizure alters the expression and daily oscillation of circadian genes in the rat frontal cortex.Jun 30, 2018

Exercise, especially aerobic exercise, effectively alleviates mental health challenges associated with circadian rhythm disruption.Jul 13, 2025

Melatonin attenuates fentanyl - induced behavioral sensitization and circadian rhythm disorders.May 14, 2024

Nobiletin could be used as an intervention that enhances circadian rhythms to combat metabolic disease via the circadian gene network.Apr 11, 2016

P. incarnata extract positively modulates circadian rhythms by inducing high-amplitude rhythms in the expression of several circadian clock genes.May 31, 2017

Taurine could be a potential target to correct or ameliorate the disturbances in circadian rhythms caused by obesity.Nov 17, 2016

The biological clock enhancer nobiletin ameliorates steatosis in obesity by restoring aberrant hepatic circadian rhythm.Aug 22, 2022

The preventive effects of pterostilbene on the exercise intolerance and circadian misalignment of mice subjected to sleep restriction.Apr 10, 2020

These effects suggest that turmeric supplementation can be used as an inexpensive intervention to prevent circadian disruption-related immunosenescence.Aug 31, 2018

Using a circadian clock based treatment in cancer therapy the tumours differed not only by their size but also by their appearance.Dec 31, 2013

Despite divergences in the reported results, ELF-MF and radio frequency electromagnetic field have to be considered as factors possibly influencing the circadian system function.Jan 01, 2014

Glioma cells are most vulnerable to the lethal effects of curcuminoids at a particular phase of the circadian cycle. Dec 31, 2015

Melatonin may be a useful treatment for Fragile X syndrome with autism spectrum.Jun 19, 2017

Pomegranate juice could modulate circadian period length.Dec 31, 2015

The therapeutic properties of ketogenic diets, slow-wave sleep, and circadian synchrony .Sep 30, 2021

This review outlines the overlooked mechanisms of electromagnetic field damage and the critical role Earth's natural electromagnetic signaling plays in the biology of the human body.Jan 01, 2015

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Circadian Rhythm

View the Evidence:
24 Abstracts with Circadian Rhythm Research