Cytokines

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2 Problem Substances Researched for Cytokines
NameACCKFocus
Aspartame12Locked
Phthalates11Locked
19 Diseases Researched for Cytokines
NameACCKFocus
Inflammation727Locked
Depressive Disorder211Locked
Cachexia: Cancer110Locked
Mood Disorders110Locked
Brain: Oxidative Stress12Locked
Cancers: All12Locked
Diabetes Mellitus: Type 212Locked
Endometriosis12Locked
Lipid Peroxidation12Locked
Skin Cancer12Locked
Skin Cancer: Prevention12Locked
Ultraviolet Radiation Induced Damage12Locked
Bipolar Disorder11Locked
Brain Inflammation 11Locked
Depression11Locked
Ebola Virus Infections11Locked
Schizophrenia11Locked
Septic Shock11Locked
Stress11Locked
1 Problematic Actions Researched for Cytokines
NameACCKFocus
Vaccination: All110Locked
3 Adverse Pharmacological Actions Researched for Cytokines
NameACCKFocus
Immunoreactive12Locked
Oxidant12Locked
Tumor necrosis factorα (TNFα) up-regulation11Locked
7 Substances Researched for Cytokines
NameACCKFocus
Melatonin23Locked
Broccoli Sprouts12Locked
Naringenin 12Locked
Selenium12Locked
Silibinin12Locked
Sulforaphane12Locked
Curcumin11Locked
25 Pharmacological Actions Researched for Cytokines
NameACCKFocus
Anti-Inflammatory Agents58Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor36Locked
Antioxidants35Locked
Anticarcinogenic Agents24Locked
Antiproliferative 24Locked
Interferon Gamma Reducer24Locked
Neuroprotective Agents23Locked
Anti Inflammatory12Locked
Anti-Angiogenic12Locked
Apoptotic12Locked
Chemopreventive12Locked
Genoprotective12Locked
Interleukin-1 beta downregulation12Locked
Interleukin-10 downregulation12Locked
Interleukin-12 downregulation12Locked
Interleukin-4 downregulation12Locked
Interleukin-5 downregulation12Locked
Interleukin-6 Downregulation12Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor12Locked
NF-kappaB Inhibitor12Locked
PI3K-AKT inhibitor12Locked
Vascular Endothelial Growth Factor Inhibitors12Locked
Antiviral Agents11Locked
Heme oxygenase-1 up-regulation11Locked
Neuroplasticity enhancement11Locked

View the Evidence:
12 Abstracts with Cytokines Research

[+]

The results strongly suggest that the NF-κB pathway plays a role in the promotion of WAT inflammation during cachexia. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 ;7(6):4465-79. Epub 2015 Jun 4. PMID: 26053616
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Cachexia: Cancer, Inflammation
Additional Keywords : Cytokines
[+]

Typhoid but not placebo injection produced an inflammatory response indexed by increased circulating interleukin-6 and significant mood reduction at 3 hours. Aug 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Psychiatry. 2009 Sep 1 ;66(5):407-14. Epub 2009 May 7. PMID: 19423079
Article Published Date : Aug 31, 2009
Study Type : Human Study
Additional Links
Diseases : Depressive Disorder, Inflammation, Mood Disorders
Additional Keywords : Cytokines
Anti Therapeutic Actions : Vaccination: All
[+]

Aspartame acts as a chemical stressor because of increased corticosterone level and increased lipid peroxidation and nitric oxide level induce generation of free radicals in serum.Feb 28, 2015

Pubmed Data : Endocrinol Nutr. 2015 Mar ;62(3):114-22. Epub 2015 Feb 11. PMID: 25681123
Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Diseases : Lipid Peroxidation
Additional Keywords : Cytokines
Problem Substances : Aspartame
Adverse Pharmacological Actions : Immunoreactive, Oxidant
[+]

Melatonin and selenium induced protective effects against diabetes-induced brain and erythrocyte oxidative injuries.Aug 04, 2015

Pubmed Data : Brain Inj. 2015 Aug 5:1-7. Epub 2015 Aug 5. PMID: 26244700
Article Published Date : Aug 04, 2015
Study Type : Animal Study
Additional Links
Substances : Melatonin, Selenium
Diseases : Brain: Oxidative Stress, Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Additional Keywords : Cytokines
[+]

Naringenin inhibits UVB irradiation-induced skin damage and may be a promising therapeutic approach to control skin disease.Jul 23, 2015

Pubmed Data : J Nat Prod. 2015 Jul 24 ;78(7):1647-55. Epub 2015 Jul 8. PMID: 26154512
Article Published Date : Jul 23, 2015
Study Type : Animal Study
Additional Links
Substances : Naringenin
Diseases : Inflammation, Skin Cancer, Skin Cancer: Prevention, Ultraviolet Radiation Induced Damage
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antioxidants, Interferon Gamma Reducer, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-4 downregulation, Interleukin-5 downregulation, Interleukin-6 Downregulation, Matrix metalloproteinase-9 (MMP-9) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Cytokines
[+]

Silibinin can modulate TI-induced FAT10 expression and also restores normal chromosome numbers to cells treated with TI.Jul 02, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biol Open. 2015 Jul 3. Epub 2015 Jul 3. PMID: 26142316
Article Published Date : Jul 02, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Silibinin
Diseases : Cancers: All, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Antiproliferative , Chemopreventive, Genoprotective, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Chromosome, Cytokines, Gene Expression Regulation
[+]

Sulforaphane exhibits antiproliferative, apoptotic, anti-inflammatory, and anti-angiogenic properties and ameliorates a rat model of endometriosis.Apr 01, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dose Response. 2019 Apr-Jun;17(2):1559325819855538. Epub 2019 Jun 11. PMID: 31217757
Article Published Date : Apr 01, 2019
Study Type : Animal Study
Additional Links
Substances : Broccoli Sprouts, Sulforaphane
Diseases : Endometriosis
Pharmacological Actions : Anti-Angiogenic, Anti Inflammatory, Antiproliferative , Apoptotic, Interferon Gamma Reducer, Interleukin-10 downregulation, PI3K-AKT inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Cytokines, Inflammation, Interleukin-6 Downregulation, women's health
[+]

A review focusing on the anti-inflammatory and anti-oxidant properties of curcumin and discuss its therapeutic potential in bipolar disorders.Apr 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Hypotheses. 2013 May ;80(5):606-12. Epub 2013 Feb 26. PMID: 23484676
Article Published Date : Apr 30, 2013
Study Type : Review
Additional Links
Substances : Curcumin
Diseases : Bipolar Disorder, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroplasticity enhancement, Neuroprotective Agents
Additional Keywords : Cytokines
[+]

A review on emerging evidence indicating potentially important role of blood brain barrier endothelial cells in peripheral immune-to-brain communication, which may be also relevant for schizophrenia.Jun 03, 2015

Pubmed Data : Psychopharmacology (Berl). 2015 Jun 4. Epub 2015 Jun 4. PMID: 26037944
Article Published Date : Jun 03, 2015
Study Type : Review
Additional Links
Diseases : Inflammation, Schizophrenia
Additional Keywords : Cytokines, Diseases that are Linked, Immune Response
[+]

Melatonin could be a useful treatment aid in ebola infections. Mar 31, 2015

Pubmed Data : J Med Virol. 2015 Apr ;87(4):537-43. Epub 2015 Jan 21. PMID: 25611054
Article Published Date : Mar 31, 2015
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Ebola Virus Infections, Inflammation, Septic Shock
Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents, Heme oxygenase-1 up-regulation
Additional Keywords : Cytokines
[+]

Results from this review have suggested that at least one phthalate has the ability to enhance tumour necrosis factor-α production from monocytes and macrophages.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(3):e0120083. Epub 2015 Mar 26. PMID: 25811352
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Additional Keywords : Cytokines, Problem Substance Synergy
Problem Substances : Phthalates
Adverse Pharmacological Actions : Tumor necrosis factorα (TNFα) up-regulation
[+]

The present review is to provide an integrated account of how life stress affects inflammation and how stress–inflammation pathways may in turn be linked with depression.Apr 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Psychol Bull. 2014 May ;140(3):774-815. Epub 2014 Jan 13. PMID: 24417575
Article Published Date : Apr 30, 2014
Study Type : Review
Additional Links
Diseases : Depression, Depressive Disorder, Inflammation, Stress
Additional Keywords : Cytokines, Diseases that are Linked, Social Stressors

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