DNA Methylation

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14 Problem Substances Researched for DNA Methylation
59 Diseases Researched for DNA Methylation
1 Problematic Actions Researched for DNA Methylation
NameACCKFocus
Cesarean Delivery220Locked
2 Adverse Pharmacological Actions Researched for DNA Methylation
NameACCKFocus
Obesogenic12Locked
Hepatotoxic11Locked
38 Substances Researched for DNA Methylation
9 Therapeutic Actions Researched for DNA Methylation
23 Pharmacological Actions Researched for DNA Methylation

View the Evidence:
78 Abstracts with DNA Methylation Research

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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nat Commun. 2021 May 14 ;12(1):2830. Epub 2021 May 14. PMID: 33990564
Study Type : Meta Analysis
Additional Links
Substances : Black Tea, Coffee
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Pubmed Data : Environ Mol Mutagen. 2017 Jul ;58(6):398-410. Epub 2017 May 28. PMID: 28556291
Study Type : Meta Analysis
Additional Links
Additional Keywords : DNA Methylation, Hypomethylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Hum Genet. 2016 Apr 7 ;98(4):680-96. Epub 2016 Mar 31. PMID: 27040690
Study Type : Meta Analysis
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genes Nutr. 2015 Sep ;10(5):480. Epub 2015 Jul 17. PMID: 26183162
Study Type : Human Study
Additional Links
Substances : Folate, Fruit: All
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Aging (Albany NY). 2021 Apr 12 ;13(7):9419-9432. Epub 2021 Apr 12. PMID: 33844651
Study Type : Human Study
Additional Links
Diseases : Aging
Therapeutic Actions : Exercise
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2021 ;16(12):e0260860. Epub 2021 Dec 2. PMID: 34855899
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2020 Jan 1 ;17(1). Epub 2020 Jan 1. PMID: 31906378
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation, Risk Factors
Problem Substances : Bisphenol A
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS Comput Biol. 2017 03 ;13(3):e1005385. Epub 2017 Mar 16. PMID: 28301476
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Epigenetics. 2019 03 29 ;11(1):56. Epub 2019 Mar 29. PMID: 30925934
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation, Gene Expression
Problem Substances : Antidepressants
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Pubmed Data : Life Sci. 2018 May 1 ;200:81-86. Epub 2018 Mar 15. PMID: 29551577
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Epigenetics. 2014 Dec 2 ;9(12):1557-69. PMID: 25484259
Study Type : Human Study
Additional Links
Therapeutic Actions : Exercise: Endurance
Pharmacological Actions : Anti Inflammatory
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Pubmed Data : Acta Paediatr. 2009 Jul ;98(7):1096-9. PMID: 19638013
Study Type : Human Study
Additional Links
Diseases : Cesarean Section
Anti Therapeutic Actions : Cesarean Delivery
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : MBio. 2014 ;5(6). Epub 2014 Dec 16. PMID: 25516615
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation, Microbiome, Risk Factors
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Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2015 Aug 11. Epub 2015 Aug 11. PMID: 26265203
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation, Risk Factors
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Pubmed Data : Epigenetics. 2019 Dec 10:1-12. Epub 2019 Dec 10. PMID: 31822152
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Psychiatry. 2014 Apr ;19(4):495-503. Epub 2013 Apr 23. PMID: 23608919
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2024 Aug ;190:108862. Epub 2024 Jun 30. PMID: 38972116
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation
Problem Substances : Parabens, Phthalates
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Brain Behav Immun. 2020 Feb ;84:36-44. Epub 2019 Nov 13. PMID: 31733290
Study Type : Human Study
Additional Links
Therapeutic Actions : Meditation
Pharmacological Actions : Immunomodulatory
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Pubmed Data : Environ Pollut. 2021 Jan 28 ;275:116601. Epub 2021 Jan 28. PMID: 33549891
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Dec 23 ;10(1). Epub 2017 Dec 23. PMID: 29295516
Study Type : Human Study
Additional Links
Substances : Nuts: All, Olive Oil
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2020 Mar 12 ;10(1):4564. Epub 2020 Mar 12. PMID: 32165663
Study Type : Human Study
Additional Links
Diseases : Aging
Therapeutic Actions : Meditation
Pharmacological Actions : Telomere Protective
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2021 ;8:689055. Epub 2021 Jun 17. PMID: 34222308
Study Type : Human Study
Additional Links
Substances : Chokeberry
Pharmacological Actions : Cardioprotective
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Obstet Gynecol. 2014 Nov ;211(5):502.e1-8. Epub 2014 Jul 1. PMID: 24996659
Study Type : Human Study
Additional Links
Anti Therapeutic Actions : Cesarean Delivery
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Redox Biol. 2016 Dec ;10:34-44. Epub 2016 Sep 21. PMID: 27687219
Study Type : Human Study
Additional Links
Diseases : Aging
Therapeutic Actions : Exercise: Resistance Training
Additional Keywords : DNA Methylation, Physical Activity
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2017 Nov ;108:127-136. Epub 2017 Aug 24. PMID: 28843141
Study Type : Human Study
Additional Links
Additional Keywords : DNA Methylation
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Pubmed Data : Inflammopharmacology. 2017 Apr ;25(2):203-210. Epub 2017 Feb 11. PMID: 28190128
Study Type : Human In Vitro, Human Study
Additional Links
Therapeutic Actions : Light Therapy, Sunlight exposure
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Epigenetics. 2023 Jan 14 ;15(1):7. Epub 2023 Jan 14. PMID: 36639817
Study Type : Human Study
Additional Links
Substances : Vitamin C
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Pubmed Data : Am J Respir Crit Care Med. 2017 Apr 19. Epub 2017 Apr 19. PMID: 28422514
Study Type : Human Study
Additional Links
Substances : Vitamin C
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2019 ;10:272. Epub 2019 Mar 26. PMID: 30971923
Study Type : Animal Study
Additional Links
Substances : Reishi Mushroom
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : DNA Methylation
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Pubmed Data : Mol Neurobiol. 2020 Jan 10. Epub 2020 Jan 10. PMID: 31919777
Study Type : Animal Study
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Pubmed Data : Environ Sci Pollut Res Int. 2019 Nov 26. Epub 2019 Nov 26. PMID: 31773524
Study Type : Animal Study
Additional Links
Additional Keywords : DNA Methylation
Problem Substances : Bisphenol A
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Pubmed Data : Environ Mol Mutagen. 2016 Jun 23. Epub 2016 Jun 23. PMID: 27334623
Study Type : Animal Study
Additional Links
Additional Keywords : DNA Methylation, Risk Factors
Problem Substances : Bisphenol A
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Pubmed Data : Eur J Pharmacol. 2020 Nov 15 ;887:173464. Epub 2020 Aug 8. PMID: 32781171
Study Type : Animal Study, In Vitro Study
Additional Links
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Pubmed Data : Chin J Nat Med. 2016 Apr ;14(4):255-64. PMID: 27114312
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Liver Fibrosis
Pharmacological Actions : Hepatoprotective
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Cell Endocrinol. 2015 Sep 28. Epub 2015 Sep 28. PMID: 26427651
Study Type : Animal Study
Additional Links
Additional Keywords : DNA Methylation
Problem Substances : Bisphenol A
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dev Biol. 2019 01 15 ;445(2):280-293. Epub 2018 Nov 27. PMID: 30500333
Study Type : Animal Study
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Invest. 2010 May ;120(5):1603-16. Epub 2010 Apr 26. PMID: 20424322
Study Type : Animal Study
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Substances : Folate, Folic Acid
Pharmacological Actions : Regenerative
Additional Keywords : DNA Methylation, Nerve Regeneration
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Pubmed Data : J Nutr Biochem. 2015 Aug ;26(8):883-91. Epub 2015 Apr 28. PMID: 25959374
Study Type : Transgenic Animal Study
Additional Links
Substances : Folate, Folic Acid
Pharmacological Actions : Neuroprotective Agents
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Reprod Toxicol. 2013 Apr ;36:104-16. Epub 2013 Jan 25. PMID: 23453003
Study Type : Animal Study
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neuropharmacology. 2015 Aug 6 ;99:500-509. Epub 2015 Aug 6. PMID: 26256422
Study Type : Animal Study
Additional Links
Diseases : Epilepsy
Pharmacological Actions : Anticonvulsants
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 2018 07 ;126(7):077006. Epub 2018 Jul 23. PMID: 30044229
Study Type : Animal Study
Additional Links
Additional Keywords : DNA Methylation
Problem Substances : Bisphenol A
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Pubmed Data : Am J Respir Cell Mol Biol. 2018 03 ;58(3):366-377. PMID: 28960086
Study Type : Animal Study
Additional Links
Additional Keywords : DNA Methylation
Problem Substances : Electronic Cigarettes
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Pubmed Data : Mol Cell Biochem. 2020 May ;468(1-2):83-96. Epub 2020 Mar 18. PMID: 32189172
Study Type : Animal Study
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Pubmed Data : Nature. 2019 Sep ;573(7773):271-275. Epub 2019 Sep 4. PMID: 31485074
Study Type : Animal Study
Additional Links
Substances : Vitamin C
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Pubmed Data : PLoS One. 2017 ;12(5):e0176155. Epub 2017 May 2. PMID: 28464002
Study Type : Animal Study
Additional Links
Problem Substances : Mercury
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Pubmed Data : Chemosphere. 2019 Oct 15 ;241:125092. Epub 2019 Oct 15. PMID: 31683443
Study Type : Animal Study
Additional Links
Additional Keywords : DNA Methylation
Problem Substances : Bisphenol S
Adverse Pharmacological Actions : Obesogenic
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Pubmed Data : Sci Total Environ. 2019 Feb 10 ;650(Pt 1):908-921. Epub 2018 Sep 7. PMID: 30308865
Study Type : Animal Study
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Pubmed Data : Environ Pollut. 2019 Dec ;255(Pt 3):113331. Epub 2019 Oct 8. PMID: 31614245
Study Type : Animal Study
Additional Links
Substances : Folic Acid
Pharmacological Actions : Cardioprotective
Additional Keywords : DNA Methylation
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Pubmed Data : Environ Toxicol. 2016 May ;31(5):584-92. Epub 2014 Nov 20. PMID: 25410620
Study Type : Animal Study
Additional Links
Additional Keywords : DNA Methylation
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Pubmed Data : Aquat Toxicol. 2017 Mar ;184:14-25. Epub 2016 Dec 8. PMID: 28068562
Study Type : Animal Study
Additional Links
Problem Substances : Uranium: Depleted
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Pubmed Data : Eur J Nutr. 2015 Jul 30. Epub 2015 Jul 30. PMID: 26224648
Study Type : Transgenic Animal Study
Additional Links
Substances : Folic Acid
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : DNA Methylation
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Pubmed Data : Mol Nutr Food Res. 2021 Jun 15:e2100417. Epub 2021 Jun 15. PMID: 34129274
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : High Fat Diet
Additional Keywords : Anti-Obesity Agents, DNA Methylation
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Pubmed Data : J Pineal Res. 2012 Jun 27. Epub 2012 Jun 27. PMID: 22856590
Study Type : In Vitro Study
Additional Links
Substances : Melatonin
Diseases : Breast Cancer
Additional Keywords : DNA Methylation
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Pubmed Data : Chem Immunol Allergy. 2012 ;98:85-99. Epub 2012 Jun 26. PMID: 22767059
Study Type : Review
Additional Links
Therapeutic Actions : Mind-Body Therapies
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Epigenetics. 2019 Sep 3 ;11(1):131. Epub 2019 Sep 3. PMID: 31481107
Study Type : Review
Additional Links
Additional Keywords : DNA Methylation
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Jan 23 ;13(2). Epub 2021 Jan 23. PMID: 33498667
Study Type : Review
Additional Links
Substances : Curcumin, Turmeric
Diseases : Breast Cancer
Pharmacological Actions : Chemopreventive
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin Herb Med. 2022 Apr ;14(2):244-253. Epub 2022 Mar 26. PMID: 36117672
Study Type : Review
Additional Links
Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive
Additional Keywords : DNA Methylation
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Pubmed Data : Annu Rev Med. 2019 Jan 27 ;70:151-166. PMID: 30691368
Study Type : Review
Additional Links
Additional Keywords : DNA Methylation
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Pubmed Data : Mol Med Rep. 2015 Aug 11. Epub 2015 Aug 11. PMID: 26299812
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Anti-metastatic
Additional Keywords : DNA Methylation
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Pubmed Data : Curr Top Med Chem. 2016 ;16(7):788-806. PMID: 26303416
Study Type : Review
Additional Links
Substances : Polyphenols
Pharmacological Actions : Cardioprotective
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Pubmed Data : Environ Pollut. 2019 Oct 2 ;255(Pt 2):113318. Epub 2019 Oct 2. PMID: 31610501
Study Type : In Vitro Study
Additional Links
Additional Keywords : DNA Methylation, Increased Risk
Problem Substances : Bisphenol A
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2018 Jan 2 ;9(1):361-374. Epub 2017 Dec 7. PMID: 29416619
Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Chemosensitizer
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2015 ;16(10):25002-13. Epub 2015 Oct 20. PMID: 26492244
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid
Pharmacological Actions : Neuroprotective Agents
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Pubmed Data : Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2019 Jul ;35(7):625-630. PMID: 31537248
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid
Pharmacological Actions : Anti-Apoptotic, Cardioprotective
Additional Keywords : DNA Methylation
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Pubmed Data : Curr Pharmacol Rep. 2015 Apr 1 ;1(2):112-120. PMID: 26005633
Study Type : Review
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Pubmed Data : Curr Pharmacol Rep. 2015 May ;1(3):179-196. Epub 2015 Jan 30. PMID: 26457242
Study Type : In Vitro Study
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Pubmed Data : Toxicol In Vitro. 2016 Mar 10 ;34:35-44. Epub 2016 Mar 10. PMID: 26970259
Study Type : In Vitro Study
Additional Links
Additional Keywords : DNA Methylation, P16 Hypermethylation
Problem Substances : Triclosan
Adverse Pharmacological Actions : Hepatotoxic
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Pubmed Data : Nutr Cancer. 2017 Aug-Sep;69(6):873-880. Epub 2017 Jul 18. PMID: 28718668
Study Type : In Vitro Study
Additional Links
Substances : Olive leaf extract
Diseases : Glioblastoma
Pharmacological Actions : Chemotherapeutic
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Clin Cases. 2019 Dec 26 ;7(24):4172-4185. PMID: 31911898
Study Type : Review
Additional Links
Pharmacological Actions : Chemopreventive
Additional Keywords : DNA Methylation
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Pubmed Data : J Nutrigenet Nutrigenomics. 2015 Sep 16 ;8(2):91-101. Epub 2015 Sep 16. PMID: 26372775
Study Type : In Vitro Study
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Epigenetics. 2017 ;9:110. Epub 2017 Oct 13. PMID: 29046732
Study Type : In Vitro Study
Additional Links
Substances : Folate, Hazelnut
Diseases : Obesity
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Pubmed Data : J Trace Elem Med Biol. 2019 Mar ;52:37-47. Epub 2018 Nov 14. PMID: 30732897
Study Type : Review
Additional Links
Problem Substances : Mercury
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Pubmed Data : Epigenetics. 2010 August 16; 5(6): 491–498.
Study Type : Review
Additional Links
Additional Keywords : DNA Methylation, Endometrial Cancer
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Pubmed Data : Mol Med Rep. 2017 Feb 28. Epub 2017 Feb 28. PMID: 28260016
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Liver Cancer
Additional Keywords : DNA Methylation
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Pubmed Data : Curr Med Chem. 2015 ;22(17):2051-64. PMID: 25891109
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Epigenomics. 2013 Dec ;5(6):729-41. PMID: 24283885
Study Type : Review
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Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:5438179. Epub 2018 Jun 6. PMID: 29977456
Study Type : Review
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Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2016 Nov 25. Epub 2016 Nov 25. PMID: 27901495
Study Type : In Vitro Study, Review
Additional Links
Substances : Vitamin B-6, Vitamin C
Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive
Additional Keywords : DNA Methylation, Hypomethylation
Problem Substances : Benzo(a)pyrene

DNA Methylation Related Articles

Written by Kelly Brogan, M.D.
The role of methylation in human health and disease is an explosive area of research, evolving all the time, and an excellent example of the power to use environmental exposures, diet, and supplementation to reclaim control over your health.

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