Drug: Doxorubicin

Name	AC	CK
Chemotherapy	1	10
Insulin	1	10
Tamoxifen	1	10
Bisphosphonates	1	3
Dexamethasone	1	3
Doxorubicin	2	3
Zoledronic Acid	1	3
Cyclophosphamide	1	2
Bisphenol A	1	1

Name	AC	CK
Chemotherapy-Induced Toxicity: Doxorubicin	20	60
Breast Cancer	13	49
Chemotherapy-Induced Toxicity	9	40
Oxidative Stress	10	33
Cancers: Drug Resistant	16	26
Lung Cancer	7	17
Chemically-Induced Liver Damage	2	12
Promyelocytic leukemia	3	12
Chemotherapy-Induced Toxicity: Cisplatin	2	11
Ovarian Cancer	2	11
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	10
Fatty Liver	1	10
Hyperglycemia	1	10
Hypertension	1	10
Insulin Resistance	1	10
Lymphoma: Mantle Cell	1	10
Nitrite Toxicity	1	10
Cardiotoxicity: Chemotherapy-Induced	4	8
Cancers: Multi-Drug Resistant	7	7
Liver Cancer	5	7
Cancers: All	4	6
Chemotherapy-Induced Toxicity: Adriamycin	3	6
Kidney Damage: Drug-Induced	2	5
Prostate Cancer	4	5
Leukemia	3	4
Lipid Peroxidation	2	4
Lymphoma	2	4
Tumors	2	3
Androgen Deficiency	1	2
Brain Injury: Hippocampal Damage	1	2
Cardiac Arrhythmias	1	2
Cataract	1	2
Cognitive Decline/Dysfunction	1	2
Congestive Heart Failure	1	2
DNA damage	1	2
Heart Failure	1	2
Inflammation	1	2
Liver Damage: Drug-Induced	1	2
Lymph Node Cancer	1	2
Nephropathy	1	2
Pancreatic Cancer	2	2
Breast Cancer: Triple Negative	1	1
Breast Cancer: estrogen receptor alpha-positive	1	1
Chemotherapy	1	1
Colon Cancer	1	1
Gastric Cancer	1	1
Kidney Fibrosis	1	1
Leukemia: Acute myelogenous leukemia (AML)	1	1
Melanoma	1	1
Non-Small-Cell Lung Carcinoma	1	1
Uterine Cancer	1	1

Name	AC	CK	Focus
Chemotherapy	2	12

Name	AC	CK
Hepatotoxic	1	10
Nephrotoxic	1	3
Neurotoxic	1	2
Chemoresistance upregulation	1	1

Name	AC	CK
Chokeberry	2	20
Curcumin	10	14
Genistein	2	11
Turkey Tail Mushroom	2	11
Caffeine	1	10
Daidzein	1	10
Isoflavones	1	10
Onion	1	10
Soy	1	10
Grape Seed Extract	3	5
Oleuropein	2	4
Resveratrol	4	4
Andrographis	2	3
Ginkgo biloba	1	3
Honey	2	3
Phellinus Linteus	2	3
Bee Propolis	1	2
Beet	2	2
Caffeic acid phenethyl ester	1	2
Catechin	1	2
Celery	1	2
Diosgenin	1	2
Fenugreek	1	2
Frankincense	1	2
Garlic	1	2
Germanium	1	2
Hazelnut	1	2
Licorice	1	2
Loquat Seeds	1	2
Milk Thistle	1	2
Parsley	1	2
Sulforaphane	2	2
Taurine	1	2
Tea	1	2
Testosterone	1	2
Thyme	1	2
Thymol	1	2
Apigenin	1	1
Berberine	1	1
Black Cohosh	1	1
Cashew	1	1
Catechols	1	1
Chrysin	1	1
Cordyceps Militaris	1	1
Coriolus versicolor	1	1
Cucurbitacin D	1	1
Emodin	1	1
Flavonoids	1	1
Lion's Mane (Hericium Erinaceus)	1	1
Parthenolide	1	1
Quercetin	1	1
Rosemaric Acid	1	1
Rosemary	1	1
Sesamol	1	1
Tanshinone IIA	1	1
Theanine	1	1
Ursolic Acid	1	1
Wogonin	1	1

Name	AC	CK	Focus
Exercise	1	10

Name	AC	CK
Antioxidants	16	47
Antineoplastic Agents	10	30
Chemoprotective Agents	7	28
Chemosensitizer	17	28
Apoptotic	19	20
Antiproliferative	11	13
Chemotherapeutic	3	12
Superoxide Dismutase Up-regulation	2	12
Cardioprotective	5	10
Hypoglycemic Agents	1	10
Insulin Sensitizers	1	10
Cell cycle arrest	8	8
Anti-Apoptotic	3	7
Hepatoprotective	3	6
Anticarcinogenic Agents	4	5
NF-kappaB Inhibitor	5	5
Renoprotective	3	5
Nrf2 activation	2	3
Antihypertensive Agents	1	2
Genoprotective	1	2
Glutathione Upregulation	1	2
Heme oxygenase-1 up-regulation	1	2
Tumor Suppressor Protein p53 Upregulation	2	2
β(2)-adrenoceptor up-regulation	1	2
Anti-Fibrotic	1	1
Anti-Inflammatory Agents	1	1
Cyclooxygenase Inhibitors	1	1
Enzyme Inhibitors	1	1
Estrogen Receptor Modulators	1	1
Heat Shock Protein Inducer	1	1
Interleukin-6 Downregulation	1	1
Lipoxygenase Inhibitors	1	1
STAT3 Inhibitor	1	1
Transforming growth factor beta (TGF-β) inhibitor	1	1
Wnt/β-catenin signaling pathway modulation	1	1

[+]

A. melanocarpa may be regarded as a promising new source of bioactive antioxidant natural compounds for breast cancer patients.Feb 28, 2013

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2013 Mar ;53:126-32. Epub 2012 Dec 5. PMID: 23220617

Article Published Date : Feb 28, 2013

Study Type : Human Study

Additional Links

Substances : Chokeberry

Diseases : Breast Cancer, Chemotherapy-Induced Toxicity, Nitrite Toxicity, Oxidative Stress

Pharmacological Actions : Antioxidants, Chemoprotective Agents, Chemotherapeutic

Additional Keywords : Drug: Doxorubicin, Plant Extracts

[+]

Acute exercise protects against doxorubicin cardiotoxicity.Sep 01, 2008

Click here to read the entire abstract

Pubmed Data : Integr Cancer Ther. 2008 Sep;7(3):147-54. PMID: 18815146

Article Published Date : Sep 01, 2008

Study Type : Human Study

Additional Links

Diseases : Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Doxorubicin, Hypertension, Oxidative Stress

Therapeutic Actions : Exercise

Additional Keywords : Drug: Doxorubicin

[+]

Caffeine potentiates chemotherapy for metastatic osteosarcoma.Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : J Orthop Sci. 2009 Sep;14(5):556-65. Epub 2009 Oct 3. PMID: 19802667

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Caffeine

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Lung Cancer

Pharmacological Actions : Antineoplastic Agents, Chemosensitizer

Additional Keywords : Drug: Doxorubicin, Drug Synergy

[+]

Consumption of fresh yellow onion ameliorates hyperglycemia and insulin resistance in breast cancer patients during doxorubicin-based chemotherapy.Aug 31, 2017

Click here to read the entire abstract

Pubmed Data : Integr Cancer Ther. 2017 Sep ;16(3):276-289. Epub 2016 Jun 28. PMID: 27352956

Article Published Date : Aug 31, 2017

Study Type : Human Study

Additional Links

Substances : Onion

Diseases : Breast Cancer, Hyperglycemia, Insulin Resistance

Pharmacological Actions : Hypoglycemic Agents, Insulin Sensitizers

Additional Keywords : Drug: Doxorubicin

Problem Substances : Insulin

[+]

Exercise preconditioning protects against doxorubicin-induced cardiac dysfunction.Oct 05, 2006

Click here to read the entire abstract

Pubmed Data : Vet Microbiol. 2006 Oct 5;117(1):59-65. PMID: 18408619

Article Published Date : Oct 05, 2006

Study Type : Human Study

Additional Links

Diseases : Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Doxorubicin

Additional Keywords : Drug: Doxorubicin

[+]

Fermented soy therapy may have therapeutic value in treating platinum-resistant ovarian cancer. Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : Gynecol Oncol. 2006 Jan;100(1):205-9. Epub 2005 Sep 19. PMID: 16171852

Article Published Date : Jan 01, 2006

Study Type : Human Study

Additional Links

Substances : Daidzein, Genistein, Isoflavones, Soy

Diseases : Cancers: Drug Resistant, Ovarian Cancer

Additional Keywords : Drug: Doxorubicin

[+]

Intensive treatment strategies may not provide superior outcomes in mantle cell lymphoma. Jul 01, 2008

Click here to read the entire abstract

Pubmed Data : Ann Oncol. 2008 Jul ;19(7):1327-30. Epub 2008 Mar 17. PMID: 18349031

Article Published Date : Jul 01, 2008

Study Type : Human Study

Additional Links

Diseases : Lymphoma: Mantle Cell

Pharmacological Actions : Antineoplastic Agents

Additional Keywords : Drug: Doxorubicin

Anti Therapeutic Actions : Chemotherapy

Problem Substances : Chemotherapy

[+]

Our results suggest that the Aronia extract supplementation in breast cancer patients has a beneficial effect on thiols concentration in plasma. Dec 31, 2012

Click here to read the entire abstract

Pubmed Data : Mol Cell Biochem. 2013 Jan ;372(1-2):47-55. Epub 2012 Sep 5. PMID: 22949034

Article Published Date : Dec 31, 2012

Study Type : Human Study

Additional Links

Substances : Chokeberry

Diseases : Breast Cancer, Chemotherapy-Induced Toxicity: Cyclophosphamide, Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Antioxidants, Chemoprotective Agents, Superoxide Dismutase Up-regulation

Additional Keywords : Drug: Doxorubicin, Plant Extracts

[+]

Tamoxifen treatment for breast cancer may result in fatty liver.Nov 01, 2000

Click here to read the entire abstract

Pubmed Data : Oncol Rep. 2000 Nov-Dec;7(6):1299-304. PMID: 11032933

Article Published Date : Nov 01, 2000

Study Type : Human Study

Additional Links

Diseases : Chemically-Induced Liver Damage, Fatty Liver

Additional Keywords : Drug: 5-flourouracil, Drug: Doxorubicin, Drug: Tamoxifen

Problem Substances : Tamoxifen

Adverse Pharmacological Actions : Hepatotoxic

[+]

Turkey tail mushroom contains a polysaccharopeptide which demonstrates chemotherapeutic activity against both leukemic and breast cancer cells.Mar 01, 2008

Click here to read the entire abstract

Pubmed Data : Int J Oncol. 2008 Mar;32(3):689-99 PMID: 18292947

Article Published Date : Mar 01, 2008

Study Type : Human Study

Additional Links

Substances : Turkey Tail Mushroom

Diseases : Breast Cancer, Promyelocytic leukemia

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

A case of acute kidney injury related to intravenous zoledronic acid in a patient with multiple myeloma has been reported.Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Nippon Jinzo Gakkai Shi. 2009;51(5):557-62. PMID: 19715164

Article Published Date : Jan 01, 2009

Study Type : Human: Case Report

Additional Links

Diseases : Kidney Damage: Drug-Induced

Additional Keywords : Drug: Doxorubicin

Problem Substances : Bisphosphonates, Dexamethasone, Zoledronic Acid

Adverse Pharmacological Actions : Nephrotoxic

[+]

Ginkgolide B exerts cardioprotective properties against doxorubicin-induced cardiotoxicity.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2016 ;11(12):e0168219. Epub 2016 Dec 14. PMID: 27973574

Article Published Date : Dec 31, 2015

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ginkgo biloba

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective

Additional Keywords : Drug: Doxorubicin

[+]

"Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy."Feb 14, 2012

Click here to read the entire abstract

Pubmed Data : Clin Cancer Res. 2012 Feb 14. Epub 2012 Feb 14. PMID: 22338017

Article Published Date : Feb 14, 2012

Study Type : Animal Study

Additional Links

Diseases : Brain Injury: Hippocampal Damage, Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Doxorubicin, Cognitive Decline/Dysfunction

Additional Keywords : Drug: Doxorubicin

Anti Therapeutic Actions : Chemotherapy

Problem Substances : Cyclophosphamide, Doxorubicin

Adverse Pharmacological Actions : Neurotoxic

[+]

Aged garlic extract and grape seed proanthocyanidin protect against doxorubicin-induced cardiotoxicity.Aug 01, 2009

Click here to read the entire abstract

Pubmed Data : Can J Physiol Pharmacol. 2009 Aug;87(8):633-40. PMID: 19767888

Article Published Date : Aug 01, 2009

Study Type : Animal Study

Additional Links

Substances : Garlic, Grape Seed Extract

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Antioxidants

Additional Keywords : Drug: Doxorubicin, Plant Extracts, Proanthocyanidins

[+]

Andrographis may be more effective an anticancer agent than Doxorubicin in lymphoma. Dec 01, 2008

Click here to read the entire abstract

Pubmed Data : Mol Biol Rep. 2008 Dec;35(4):535-40. Epub 2007 Sep 5. PMID: 17805989

Article Published Date : Dec 01, 2008

Study Type : Animal Study

Additional Links

Substances : Andrographis

Diseases : Lymph Node Cancer, Lymphoma

Pharmacological Actions : Anticarcinogenic Agents, Antioxidants

Additional Keywords : Drug: Doxorubicin, Plant Extracts, Superiority of Natural Substances versus Drugs

[+]

Anti-arrhythmia potential of honey-processed licorice.Nov 14, 2023

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2023 Nov 15 ;316:116724. Epub 2023 Jun 10. PMID: 37308027

Article Published Date : Nov 14, 2023

Study Type : Animal Study

Additional Links

Substances : Honey, Licorice

Diseases : Cardiac Arrhythmias, Chemotherapy-Induced Toxicity: Doxorubicin, Oxidative Stress

Pharmacological Actions : Antioxidants, Cardioprotective, Chemoprotective Agents, Superoxide Dismutase Up-regulation

Additional Keywords : Drug: Doxorubicin

[+]

Caffeic acid phenetyl ester, a compound found within bee propolis, protects against doxorubucin-induced cardiotoxicity in rats. Sep 30, 2010

Click here to read the entire abstract

Pubmed Data : Am J Ind Med. 2010 Sep 30. Epub 2010 Sep 30. PMID: 14745846

Article Published Date : Sep 30, 2010

Study Type : Animal Study

Additional Links

Substances : Bee Propolis, Caffeic acid phenethyl ester

Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Antioxidants

Additional Keywords : Drug: Doxorubicin

[+]

Celery has a protective effect against doxorubicin toxicity. Jan 01, 2009

Click here to read the entire abstract

Pubmed Data : Molecules. 2009 ;14(4):1627-38. Epub 2009 Apr 24. PMID: 19396021

Article Published Date : Jan 01, 2009

Study Type : Animal Study

Additional Links

Substances : Celery

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Lipid Peroxidation

Pharmacological Actions : Antioxidants

Additional Keywords : Drug: Doxorubicin, Plant Extracts

[+]

Curcumin attenuates acute adriamycin myocardial toxicity in rats.Jun 01, 1998

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 1998 Jun;124(3):425-7. PMID: 9647462

Article Published Date : Jun 01, 1998

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Chemotherapy-Induced Toxicity: Adriamycin

Pharmacological Actions : Cardioprotective

Additional Keywords : Drug: Doxorubicin

[+]

Curcumin can inhibit tumour growth in a xenograft animal model in vivo.Jan 13, 2010

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2010 Jan 13;24(2):189-192. Epub 2010 Jan 13. PMID: 20077433

Article Published Date : Jan 13, 2010

Study Type : Transgenic Animal Study

Additional Links

Substances : Curcumin

Diseases : Lung Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

Curcumin prevents adriamycin nephrotoxicity in rats.Jan 01, 2000

Click here to read the entire abstract

Pubmed Data : Br J Pharmacol. 2000 Jan;129(2):231-4. PMID: 10694226

Article Published Date : Jan 01, 2000

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Chemotherapy-Induced Toxicity: Adriamycin, Kidney Damage: Drug-Induced, Oxidative Stress

Pharmacological Actions : Renoprotective

Additional Keywords : Drug: Doxorubicin

[+]

Curcumin protects against doxorubicin (adriamycin)-induced toxicity in rats.Apr 01, 2009

Click here to read the entire abstract

Pubmed Data : J Med Food. 2009 Apr;12(2):394-402. PMID: 19459743

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Chemically-Induced Liver Damage, Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Antioxidants

Additional Keywords : Drug: Doxorubicin, Drug Side Effect Attenuation, Plant Extracts

[+]

Diosgenin, a compound isolated from fenugreek, has chemosensitizing activity against human liver cancer cells. Jan 04, 2010

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 2010 Jan 4. Epub 2010 Jan 4. PMID: 20053498

Article Published Date : Jan 04, 2010

Study Type : Animal Study

Additional Links

Substances : Diosgenin, Fenugreek

Diseases : Liver Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Drug: Doxorubicin, Drug: Paclitaxel, Drug-Plant-Vitamin Synergies

[+]

Germanium compounds may have therapeutic value in the treatment of various cancers.Apr 01, 1985

Click here to read the entire abstract

Pubmed Data : J Biol Response Mod. 1985 Apr;4(2):159-68. PMID: 3998767

Article Published Date : Apr 01, 1985

Study Type : Animal Study

Additional Links

Substances : Germanium

Diseases : Cancers: All, Leukemia, Lymphoma

Pharmacological Actions : Antineoplastic Agents

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

Grape seed extract has a protective role against doxorubicin-induced cardiotoxicity and genotoxicity in albino mice.Aug 01, 2010

Click here to read the entire abstract

Pubmed Data : J Med Food. 2010 Aug;13(4):917-25. PMID: 20553142

Article Published Date : Aug 01, 2010

Study Type : Animal Study

Additional Links

Substances : Grape Seed Extract

Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy-Induced Toxicity: Doxorubicin, DNA damage

Pharmacological Actions : Cardioprotective, Genoprotective

Additional Keywords : Drug: Doxorubicin

[+]

Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer.Jul 01, 2010

Click here to read the entire abstract

Pubmed Data : Int J Oncol. 2010 Jul ;37(1):111-23. PMID: 20514403

Article Published Date : Jul 01, 2010

Study Type : Animal Study

Additional Links

Substances : Catechin , Tea

Diseases : Cancers: Drug Resistant, Liver Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Drug: Doxorubicin, Drug Synergy

[+]

Hazelnut prevented doxorubicin-induced cataract in low doses.Aug 01, 2005

Click here to read the entire abstract

Pubmed Data : Med Sci Monit. 2005 Aug;11(8):BR300-4. Epub 2005 Jul 25. PMID: 16049376

Article Published Date : Aug 01, 2005

Study Type : Animal Study

Additional Links

Substances : Hazelnut

Diseases : Cataract, Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Antioxidants

Additional Keywords : Drug: Doxorubicin

[+]

Loquat seed inhibits oxidative stress associated wtih adriamycin-induced nephropathy. Dec 01, 2004

Click here to read the entire abstract

Pubmed Data : Biol Pharm Bull. 2004 Dec;27(12):1961-4. PMID: 15577213

Article Published Date : Dec 01, 2004

Study Type : Animal Study

Additional Links

Substances : Loquat Seeds

Diseases : Chemotherapy-Induced Toxicity: Adriamycin, Lipid Peroxidation, Nephropathy, Oxidative Stress

Pharmacological Actions : Glutathione Upregulation , Renoprotective

Additional Keywords : Drug: Doxorubicin, Plant Extracts

[+]

Oleuropein confers protection against doxorubicin-induced cardiotoxicity. Jul 01, 2009

Click here to read the entire abstract

Pubmed Data : NMR Biomed. 2009 Jul;22(6):585-92. PMID: 19308947

Article Published Date : Jul 01, 2009

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Antihypertensive Agents, Antioxidants

Additional Keywords : Drug: Doxorubicin

[+]

Oleuropein prevents doxorubicin-induced cardiotoxicity and improves therapeutic outcome. Mar 01, 2007

Click here to read the entire abstract

Pubmed Data : J Mol Cell Cardiol. 2007 Mar;42(3):549-58. Epub 2007 Jan 16. PMID: 17223128

Article Published Date : Mar 01, 2007

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : Cardiotoxicity: Chemotherapy-Induced, Chemotherapy-Induced Toxicity, Chemotherapy-Induced Toxicity: Doxorubicin, Oxidative Stress

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

Parsley and celery juices restore antioxidant activity in doxorubicin-treated rats.Sep 03, 2010

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2010 Sep 3 ;15(9):6193-204. Epub 2010 Sep 3. PMID: 20877216

Article Published Date : Sep 03, 2010

Study Type : Animal Study

Additional Links

Substances : Parsley

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Antioxidants

Additional Keywords : Drug: Doxorubicin

[+]

Phellinus linteus has a synergistic effect with the drug doxorubicin in prostate cancer. Aug 07, 2006

Click here to read the entire abstract

Pubmed Data : Br J Cancer. 2006 Aug 7;95(3):282-8. Epub 2006 Jul 25. PMID: 16868541

Article Published Date : Aug 07, 2006

Study Type : Animal Study

Additional Links

Substances : Phellinus Linteus

Diseases : Prostate Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

Protective effect of boswellic acids against doxorubicin-induced hepatotoxicity.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:8296451. Epub 2018 Feb 6. PMID: 29541348

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Frankincense

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Liver Damage: Drug-Induced

Pharmacological Actions : Antioxidants, Chemoprotective Agents, Heme oxygenase-1 up-regulation, Hepatoprotective, Nrf2 activation

Additional Keywords : Drug: Doxorubicin

[+]

Restoration of appropriate testosterone levels may have therapeutic value in the treatment of heart failure.Apr 28, 2011

Click here to read the entire abstract

Pubmed Data : Gen Comp Endocrinol. 2011 Apr 28. Epub 2011 Apr 28. PMID: 21549119

Article Published Date : Apr 28, 2011

Study Type : Animal Study

Additional Links

Substances : Testosterone

Diseases : Androgen Deficiency, Congestive Heart Failure, Heart Failure

Pharmacological Actions : β(2)-adrenoceptor up-regulation

Additional Keywords : Chemotherapy Induced Toxicity, Drug: Doxorubicin

[+]

Silymarin, a compound found within milk thistle, has a protective effect against Doxorubicin-induced oxidative stress and liver damage. Feb 05, 2010

Click here to read the entire abstract

Pubmed Data : Toxicol Appl Pharmacol. 2010 Feb 5. Epub 2010 Feb 5. PMID: 20144634

Article Published Date : Feb 05, 2010

Study Type : Animal Study

Additional Links

Substances : Milk Thistle

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hepatoprotective

Additional Keywords : Drug: Doxorubicin

[+]

Taurine potentiates the antitumor activity of doxorubicin. Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : Biol Pharm Bull. 2009 Sep;32(9):1584-7. PMID: 19721236

Article Published Date : Sep 01, 2009

Study Type : Animal Study

Additional Links

Substances : Taurine

Diseases : Cancers: All, Tumors

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

Thyme oil and thymol counter doxorubicin-induced hepatotoxicityDec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oxid Med Cell Longev. 2022 ;2022:6702773. Epub 2022 Feb 7. PMID: 35178158

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Thyme, Thymol

Diseases : Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Chemoprotective Agents, Hepatoprotective

Additional Keywords : Drug: Doxorubicin

[+]

Activation of SIRT3 by Tanshinone IIA ameliorates renal fibrosis.Sep 30, 2024

Click here to read the entire abstract

Pubmed Data : Cell Signal. 2024 Oct ;122:111348. Epub 2024 Aug 15. PMID: 39153586

Article Published Date : Sep 30, 2024

Study Type : In Vitro Study

Additional Links

Substances : Tanshinone IIA

Diseases : Kidney Fibrosis, Oxidative Stress

Pharmacological Actions : Anti-Fibrotic, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor

Additional Keywords : Drug: Doxorubicin

[+]

Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis.Aug 31, 2023

Click here to read the entire abstract

Pubmed Data : Free Radic Biol Med. 2023 Sep ;206:13-21. Epub 2023 Jun 25. PMID: 37364691

Article Published Date : Aug 31, 2023

Study Type : In Vitro Study

Additional Links

Substances : Emodin

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Oxidative Stress

Pharmacological Actions : Antioxidants, Cardioprotective, Chemoprotective Agents, Nrf2 activation

Additional Keywords : Drug: Doxorubicin

[+]

Andrographis contains a compound which enhances chemosensitivity of cancer cells to doxorubicin.May 01, 2010

Click here to read the entire abstract

Pubmed Data : Biochem Pharmacol. 2010 May 1;79(9):1242-50. Epub 2009 Dec 21. PMID: 20026083

Article Published Date : May 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Andrographis

Diseases : Cancers: All

Pharmacological Actions : Apoptotic, Chemosensitizer

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

Apigenin may have a therapeutic role in the treatment of multi-drug resistant cancers. Sep 10, 2009

Click here to read the entire abstract

Pubmed Data : J Med Chem. 2009 Sep 10;52(17):5311-22. PMID: 19725578

Article Published Date : Sep 10, 2009

Study Type : In Vitro Study

Additional Links

Substances : Apigenin

Diseases : Cancers: Multi-Drug Resistant

Additional Keywords : Drug: Doxorubicin

[+]

Beetroot extract has 10 times lower toxicity than the chemo-agent doxorubicin; it has anti-cancer properties against breast and prostate cancer cells.Feb 28, 2011

Click here to read the entire abstract

Pubmed Data : Anticancer Agents Med Chem. 2011 Mar ;11(3):280-4. PMID: 21434853

Article Published Date : Feb 28, 2011

Study Type : In Vitro Study

Additional Links

Substances : Beet

Diseases : Breast Cancer, Prostate Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative

Additional Keywords : Drug: Doxorubicin, Natural Substance Synergy, Plant Extracts

[+]

Berberine increases doxorubicin sensitivity by suppressing STAT3 in lung cancer.Oct 26, 2015

Click here to read the entire abstract

Pubmed Data : Am J Chin Med. 2015 Oct 27:1-16. Epub 2015 Oct 27. PMID: 26503561

Article Published Date : Oct 26, 2015

Study Type : In Vitro Study

Additional Links

Substances : Berberine

Diseases : Lung Cancer

Pharmacological Actions : Chemosensitizer, STAT3 Inhibitor

Additional Keywords : Drug: Doxorubicin

[+]

Black cohosh potentiates the antiproliferative effects of chemotherapy agents on human breast cancer cells. Oct 01, 2006

Click here to read the entire abstract

Pubmed Data : Planta Med. 2006 Oct;72(13):1200-6. Epub 2006 Sep 20. PMID: 16988912

Article Published Date : Oct 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Black Cohosh

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative , Cell cycle arrest

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

BPA at environmentally relevant doses reduces the efficacy of chemotherapeutic agents doxorubicin, cisplatin, and vinblastine.Jan 31, 2009

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Environ Health Perspect. 2009 Feb ;117(2):175-80. Epub 2008 Oct 8. PMID: 19270784

Article Published Date : Jan 31, 2009

Study Type : In Vitro Study

Additional Links

Diseases : Breast Cancer, Breast Cancer: estrogen receptor alpha-positive, Breast Cancer: Triple Negative

Pharmacological Actions : Apoptotic, Estrogen Receptor Modulators

Additional Keywords : Drug: Cisplatin, Drug: Doxorubicin, Drug: Vinblastine

Problem Substances : Bisphenol A

Adverse Pharmacological Actions : Chemoresistance upregulation

[+]

Cashew contains an anticancer catechol with activity against multidrug resistant cancer cell lines.Apr 21, 2009

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2009 Apr 21;122(3):450-6. Epub 2009 Feb 10. PMID: 19429311

Article Published Date : Apr 21, 2009

Study Type : In Vitro Study

Additional Links

Substances : Cashew, Catechols

Diseases : Cancers: Multi-Drug Resistant, Leukemia, Tumors

Pharmacological Actions : Apoptotic, Cell cycle arrest

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies, Plant Extracts

[+]

Cucurbitacin D decreases cell proliferation and induces apoptosis in doxorubicin-resistant breast cancer cells.Oct 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Cell Biochem. 2015 Nov ;409(1-2):33-43. Epub 2015 Jul 14. PMID: 26169986

Article Published Date : Oct 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Cucurbitacin D

Diseases : Breast Cancer, Cancers: Drug Resistant

Pharmacological Actions : Antiproliferative , Apoptotic, Chemotherapeutic, NF-kappaB Inhibitor

Additional Keywords : Drug: Doxorubicin

[+]

Curcumin down-regulates multidrug-resistance. Jan 18, 2008

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 2008 Jan 18;259(1):111-8. Epub 2007 Nov 19. PMID: 18006147

Article Published Date : Jan 18, 2008

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant

Pharmacological Actions : NF-kappaB Inhibitor

Additional Keywords : Drug: Doxorubicin

[+]

Curcumin enhances the effectiveness of doxorubicin. Oct 31, 2011

Click here to read the entire abstract

Pubmed Data : Pharmazie. 2011 Nov ;66(11):871-4. PMID: 22204133

Article Published Date : Oct 31, 2011

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Chemotherapy-Induced Toxicity

Pharmacological Actions : Chemosensitizer

Additional Keywords : Drug: Doxorubicin, Drug Synergy

Problem Substances : Doxorubicin

[+]

Curcumin has antiproliferative effects against human breast tumor cell lines.Jun 01, 1997

Click here to read the entire abstract

Pubmed Data : Anticancer Drugs. 1997 Jun;8(5):470-81. PMID: 9215611

Article Published Date : Jun 01, 1997

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Breast Cancer, Cancers: Drug Resistant, Cancers: Multi-Drug Resistant

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Cell cycle arrest

Additional Keywords : Drug: Doxorubicin

[+]

Curcumin inhibits the growth of breast cancer through the manipulation of the arachidonate metabolism. Jan 01, 2007

Click here to read the entire abstract

Pubmed Data : BMC Cancer. 2007;7:138. Epub 2007 Jul 25. PMID: 17651499

Article Published Date : Jan 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Breast Cancer, Cancers: Drug Resistant

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase Inhibitors, Lipoxygenase Inhibitors

Additional Keywords : Drug: Doxorubicin

[+]

Curcumin reduces multi-drug resistance in uterine cancer cells.Oct 01, 2008

Click here to read the entire abstract

Pubmed Data : Oncol Rep. 2008 Oct;20(4):731-5. PMID: 18813811

Article Published Date : Oct 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cancers: Multi-Drug Resistant, Uterine Cancer

Pharmacological Actions : Apoptotic, Chemosensitizer

Additional Keywords : Drug: Doxorubicin

[+]

Curcumin reduces NF-kappa B factor activation associated with anticancer drugs. Dec 01, 2009

Click here to read the entire abstract

Pubmed Data : Endocr Relat Cancer. 2009 Dec;16(4):1339-50. Epub 2009 Sep 2. PMID: 12007574

Article Published Date : Dec 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Chemotherapy, Chemotherapy-Induced Toxicity

Pharmacological Actions : Antineoplastic Agents, NF-kappaB Inhibitor

Additional Keywords : Drug: Doxorubicin, Drug: Tamoxifen

[+]

Genistein acts as a chemosensitzer, contributing to overcoming drug-resistance in prostate, breast, lung and pancreatic ancers. Aug 01, 2005

Click here to read the entire abstract

Pubmed Data : Cancer Res. 2005 Aug 1;65(15):6934-42. PMID: 16061678

Article Published Date : Aug 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Genistein

Diseases : Breast Cancer, Cancers: Drug Resistant, Chemotherapy-Induced Toxicity: Cisplatin, Lung Cancer, Pancreatic Cancer, Prostate Cancer

Pharmacological Actions : Apoptotic, NF-kappaB Inhibitor

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

Grape seed extract and the conventional cytotoxic agent doxorubicin have a synergistic effect against human breast cancer cells. May 01, 2004

Click here to read the entire abstract

Pubmed Data : Breast Cancer Res Treat. 2004 May;85(1):1-12. PMID: 15039593

Article Published Date : May 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Grape Seed Extract

Diseases : Breast Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies, Plant Extracts

[+]

Lion's main enhances doxorubicin-induced apoptosis in human hepatocellular carcinoma cells.Nov 28, 2010

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 2010 Nov 28 ;297(2):144-54. PMID: 20554107

Article Published Date : Nov 28, 2010

Study Type : In Vitro Study

Additional Links

Substances : Lion's Mane (Hericium Erinaceus)

Diseases : Liver Cancer

Pharmacological Actions : Apoptotic, Chemosensitizer

Additional Keywords : Drug: Doxorubicin

[+]

Parthenolide reverses doxorubicin resistance in human lung carcinoma A549 cells.Aug 13, 2013

Click here to read the entire abstract

Pubmed Data : Toxicol Lett. 2013 Aug 14 ;221(2):73-82. Epub 2013 Jun 20. PMID: 23792430

Article Published Date : Aug 13, 2013

Study Type : In Vitro Study

Additional Links

Substances : Parthenolide

Diseases : Cancers: Drug Resistant, Lung Cancer

Pharmacological Actions : Chemotherapeutic, Heat Shock Protein Inducer, NF-kappaB Inhibitor

Additional Keywords : Drug: Doxorubicin

[+]

Quercetin induces programmed cell death in human myeloid leukemia cells and their doxorubicin resistant variants. Jan 01, 2005

Click here to read the entire abstract

Pubmed Data : Neoplasma. 2005;52(4):273-9. PMID: 16059641

Article Published Date : Jan 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Quercetin

Diseases : Cancers: Drug Resistant, Promyelocytic leukemia

Pharmacological Actions : Apoptotic

Additional Keywords : Drug: Doxorubicin

[+]

Resveratrol attenuates doxorubicin-induced cellular damage by modulating nitric oxide and apoptosis.Dec 06, 2010

Click here to read the entire abstract

Pubmed Data : Exp Toxicol Pathol. 2010 Dec 6. Epub 2010 Dec 6. PMID: 21144718

Article Published Date : Dec 06, 2010

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Apoptotic

Additional Keywords : Drug: Doxorubicin

[+]

Resveratrol induces cell-cycle disruption and programmed cell death in chemoresistant melanoma.Jul 01, 2010

Click here to read the entire abstract

Pubmed Data : J Cell Biochem. 2010 Jul 1;110(4):893-902. PMID: 20564188

Article Published Date : Jul 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol

Diseases : Cancers: Drug Resistant, Melanoma

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Cell cycle arrest, Chemosensitizer

Additional Keywords : Drug: Doxorubicin, Stilbenes

[+]

Resveratrol reverses doxorubicin resistance in acute myeloid leukemia cells.Jan 01, 2008

Click here to read the entire abstract

Pubmed Data : Environ Health. 2008;7:21. Epub 2008 May 30. PMID: 20350534

Article Published Date : Jan 01, 2008

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol

Diseases : Leukemia: Acute myelogenous leukemia (AML)

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Drug: Doxorubicin, Stilbenes

[+]

Resveratrol sensitizes resistant leukemia cells to the the effects of anticancer drugs. Jan 01, 2006

Click here to read the entire abstract

Pubmed Data : Neoplasma. 2006;53(5):384-92. PMID: 17013532

Article Published Date : Jan 01, 2006

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol

Diseases : Leukemia

Pharmacological Actions : Anticarcinogenic Agents, Apoptotic, Cell cycle arrest, Chemosensitizer

Additional Keywords : Drug: Doxorubicin, Stilbenes

[+]

Reversal effect of rosmarinic acid on multidrug resistance in gastric cancer cells.Dec 31, 2012

Click here to read the entire abstract

Pubmed Data : J Asian Nat Prod Res. 2013 ;15(3):276-85. Epub 2013 Feb 19. PMID: 23421517

Article Published Date : Dec 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Rosemaric Acid, Rosemary

Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant, Gastric Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Drug: Doxorubicin

[+]

Review: Genetic and epigenetic modeling of the origins of multidrug-resistant cells in a human sarcoma cell line.Oct 15, 2005

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Res. 2005 Oct 15 ;65(20):9388-97. PMID: 16230402

Article Published Date : Oct 15, 2005

Study Type : Review

Additional Links

Diseases : Cancers: Drug Resistant, Cancers: Multi-Drug Resistant

Additional Keywords : Drug: Doxorubicin, Multidrug Resistance

[+]

Sufloraphane reduces doxorubicin resistance.Oct 10, 2006

Click here to read the entire abstract

Pubmed Data : Mutat Res. 2006 Oct 10;601(1-2):92-101. Epub 2006 Jul 14. PMID: 16843502

Article Published Date : Oct 10, 2006

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane

Diseases : Cancers: Drug Resistant

Pharmacological Actions : Anticarcinogenic Agents, Apoptotic, Chemosensitizer, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

Synergistic cytotoxicity of red beetroot (Beta vulgaris L.) extract with doxorubicin in human pancreatic, breast and prostate cancer cell lines.Dec 31, 2012

Click here to read the entire abstract

Pubmed Data : J Complement Integr Med. 2013 ;10(1):1-10. Epub 2013 Jun 26. PMID: 23828331

Article Published Date : Dec 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Beet

Diseases : Breast Cancer, Cancers: Drug Resistant, Pancreatic Cancer, Prostate Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Drug: Doxorubicin, Natural Substance/Drug Synergy

[+]

The association of sulforaphane-doxorubicin may therefore allow doxorubicin to be administered at lower doses, thereby reducing its potential toxicity.Jan 01, 2007

Click here to read the entire abstract

Pubmed Data : Ann N Y Acad Sci. 2007 Jan;1095:62-9. PMID: 17404018

Article Published Date : Jan 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Anticarcinogenic Agents, Chemosensitizer, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

The mushroom Phellinus Linteus induces programmed cell death and arrests growth in human lung cancer cells. Feb 01, 2007

Click here to read the entire abstract

Pubmed Data : Mol Carcinog. 2007 Feb;46(2):144-54. PMID: 17131292

Article Published Date : Feb 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Phellinus Linteus

Diseases : Lung Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest

Additional Keywords : Drug: Doxorubicin

[+]

Theanine enhances the antitumor efficacy of chemotherapeutic agents. Dec 05, 2003

Click here to read the entire abstract

Pubmed Data : Biochim Biophys Acta. 2003 Dec 5;1653(2):47-59. PMID: 14643924

Article Published Date : Dec 05, 2003

Study Type : Review

Additional Links

Substances : Theanine

Diseases : Cancers: All, Ovarian Cancer

Pharmacological Actions : Antineoplastic Agents, Enzyme Inhibitors

Additional Keywords : Drug: Doxorubicin, Drug-Plant-Vitamin Synergies

[+]

This data showed a synergistic inhibitory effect of manuka honey on doxorubicin-mediated apoptotic cell death in liver cancer cells.May 27, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Res. 2021 May 28 ;54(1):16. Epub 2021 May 28. PMID: 34049576

Article Published Date : May 27, 2021

Study Type : In Vitro Study

Additional Links

Substances : Honey

Diseases : Liver Cancer

Pharmacological Actions : Apoptotic, Chemosensitizer, Wnt/β-catenin signaling pathway modulation

Additional Keywords : Drug: Doxorubicin

[+]

This reflects the significance of sesamol in ameliorating the deleterious effects associated with cancer chemotherapy.Jun 30, 2013

Click here to read the entire abstract

Pubmed Data : J Pharm Pharmacol. 2013 Jul ;65(7):1083-93. Epub 2013 Apr 22. PMID: 23738736

Article Published Date : Jun 30, 2013

Study Type : In Vitro Study

Additional Links

Substances : Sesamol

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Oxidative Stress

Pharmacological Actions : Antioxidants, Chemoprotective Agents

Additional Keywords : Drug: Doxorubicin

[+]

Turkey tail mushroom (C. versicolor) potentiates the anti-cancer activity of the chemotherapy drugs doxorubicin and etoposide against human promyelocytic leukemia cells. Jul 01, 2005

Click here to read the entire abstract

Pubmed Data : Oncol Rep. 2005 Jul;14(1):145-55. PMID: 15944782

Article Published Date : Jul 01, 2005

Study Type : In Vitro Study

Additional Links

Substances : Coriolus versicolor, Turkey Tail Mushroom

Diseases : Promyelocytic leukemia

Pharmacological Actions : Apoptotic, Cell cycle arrest

Additional Keywords : Drug: Doxorubicin, Drug: Etoposide, Drug-Plant-Vitamin Synergies

[+]

Ursolic acid induces doxorubicin-resistant liver cancer cell death.Dec 01, 2010

Click here to read the entire abstract

Pubmed Data : Cancer Lett. 2010 Dec 1;298(1):128-38. Epub 2010 Jul 13. PMID: 20630652

Article Published Date : Dec 01, 2010

Study Type : In Vitro Study

Additional Links

Substances : Ursolic Acid

Diseases : Cancers: Drug Resistant, Liver Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Drug: Doxorubicin

[+]

Virtual screening for biomimetic anti-cancer peptides from Cordyceps militaris putative pepsinized peptidome and validation on colon cancer cell line.Sep 22, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2021 Sep 23 ;26(19). Epub 2021 Sep 23. PMID: 34641308

Article Published Date : Sep 22, 2021

Study Type : In Vitro Study

Additional Links

Substances : Cordyceps Militaris

Diseases : Colon Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Drug: Doxorubicin, Drug Synergy, Fungal Proteins

[+]

Wogonin and chrysin may contribute to overcoming drug resistance in non-small cell lung cancer cells. May 01, 2007

Click here to read the entire abstract

Pubmed Data : Int J Cancer. 2007 May 1;120(9):2019-27. PMID: 17266043

Article Published Date : May 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Chrysin, Flavonoids, Wogonin

Diseases : Cancers: Drug Resistant, Lung Cancer, Non-Small-Cell Lung Carcinoma

Pharmacological Actions : Apoptotic, Cell cycle arrest, Interleukin-6 Downregulation

Additional Keywords : Drug: Doxorubicin

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View the Evidence: 75 Abstracts with Drug: Doxorubicin Research

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A. melanocarpa may be regarded as a promising new source of bioactive antioxidant natural compounds for breast cancer patients.Feb 28, 2013

Acute exercise protects against doxorubicin cardiotoxicity.Sep 01, 2008

Caffeine potentiates chemotherapy for metastatic osteosarcoma.Sep 01, 2009

Consumption of fresh yellow onion ameliorates hyperglycemia and insulin resistance in breast cancer patients during doxorubicin-based chemotherapy.Aug 31, 2017

Exercise preconditioning protects against doxorubicin-induced cardiac dysfunction.Oct 05, 2006

Fermented soy therapy may have therapeutic value in treating platinum-resistant ovarian cancer. Jan 01, 2006

Intensive treatment strategies may not provide superior outcomes in mantle cell lymphoma. Jul 01, 2008

Our results suggest that the Aronia extract supplementation in breast cancer patients has a beneficial effect on thiols concentration in plasma. Dec 31, 2012

Tamoxifen treatment for breast cancer may result in fatty liver.Nov 01, 2000

Turkey tail mushroom contains a polysaccharopeptide which demonstrates chemotherapeutic activity against both leukemic and breast cancer cells.Mar 01, 2008

A case of acute kidney injury related to intravenous zoledronic acid in a patient with multiple myeloma has been reported.Jan 01, 2009

Ginkgolide B exerts cardioprotective properties against doxorubicin-induced cardiotoxicity.Dec 31, 2015

"Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy."Feb 14, 2012

Aged garlic extract and grape seed proanthocyanidin protect against doxorubicin-induced cardiotoxicity.Aug 01, 2009

Andrographis may be more effective an anticancer agent than Doxorubicin in lymphoma. Dec 01, 2008

Anti-arrhythmia potential of honey-processed licorice.Nov 14, 2023

Caffeic acid phenetyl ester, a compound found within bee propolis, protects against doxorubucin-induced cardiotoxicity in rats. Sep 30, 2010

Celery has a protective effect against doxorubicin toxicity. Jan 01, 2009

Curcumin attenuates acute adriamycin myocardial toxicity in rats.Jun 01, 1998

Curcumin can inhibit tumour growth in a xenograft animal model in vivo.Jan 13, 2010

Curcumin prevents adriamycin nephrotoxicity in rats.Jan 01, 2000

Curcumin protects against doxorubicin (adriamycin)-induced toxicity in rats.Apr 01, 2009

Diosgenin, a compound isolated from fenugreek, has chemosensitizing activity against human liver cancer cells. Jan 04, 2010

Germanium compounds may have therapeutic value in the treatment of various cancers.Apr 01, 1985

Grape seed extract has a protective role against doxorubicin-induced cardiotoxicity and genotoxicity in albino mice.Aug 01, 2010

Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer.Jul 01, 2010

Hazelnut prevented doxorubicin-induced cataract in low doses.Aug 01, 2005

Loquat seed inhibits oxidative stress associated wtih adriamycin-induced nephropathy. Dec 01, 2004

Oleuropein confers protection against doxorubicin-induced cardiotoxicity. Jul 01, 2009

Oleuropein prevents doxorubicin-induced cardiotoxicity and improves therapeutic outcome. Mar 01, 2007

Parsley and celery juices restore antioxidant activity in doxorubicin-treated rats.Sep 03, 2010

Phellinus linteus has a synergistic effect with the drug doxorubicin in prostate cancer. Aug 07, 2006

Protective effect of boswellic acids against doxorubicin-induced hepatotoxicity.Dec 31, 2017

Restoration of appropriate testosterone levels may have therapeutic value in the treatment of heart failure.Apr 28, 2011

Silymarin, a compound found within milk thistle, has a protective effect against Doxorubicin-induced oxidative stress and liver damage. Feb 05, 2010

Taurine potentiates the antitumor activity of doxorubicin. Sep 01, 2009

Thyme oil and thymol counter doxorubicin-induced hepatotoxicityDec 31, 2021

Activation of SIRT3 by Tanshinone IIA ameliorates renal fibrosis.Sep 30, 2024

Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis.Aug 31, 2023

Andrographis contains a compound which enhances chemosensitivity of cancer cells to doxorubicin.May 01, 2010

Apigenin may have a therapeutic role in the treatment of multi-drug resistant cancers. Sep 10, 2009

Beetroot extract has 10 times lower toxicity than the chemo-agent doxorubicin; it has anti-cancer properties against breast and prostate cancer cells.Feb 28, 2011

Berberine increases doxorubicin sensitivity by suppressing STAT3 in lung cancer.Oct 26, 2015

Black cohosh potentiates the antiproliferative effects of chemotherapy agents on human breast cancer cells. Oct 01, 2006

BPA at environmentally relevant doses reduces the efficacy of chemotherapeutic agents doxorubicin, cisplatin, and vinblastine.Jan 31, 2009

Cashew contains an anticancer catechol with activity against multidrug resistant cancer cell lines.Apr 21, 2009

Cucurbitacin D decreases cell proliferation and induces apoptosis in doxorubicin-resistant breast cancer cells.Oct 31, 2015

Curcumin down-regulates multidrug-resistance. Jan 18, 2008

Curcumin enhances the effectiveness of doxorubicin. Oct 31, 2011

Curcumin has antiproliferative effects against human breast tumor cell lines.Jun 01, 1997

Curcumin inhibits the growth of breast cancer through the manipulation of the arachidonate metabolism. Jan 01, 2007

Curcumin reduces multi-drug resistance in uterine cancer cells.Oct 01, 2008

Curcumin reduces NF-kappa B factor activation associated with anticancer drugs. Dec 01, 2009

Genistein acts as a chemosensitzer, contributing to overcoming drug-resistance in prostate, breast, lung and pancreatic ancers. Aug 01, 2005

Grape seed extract and the conventional cytotoxic agent doxorubicin have a synergistic effect against human breast cancer cells. May 01, 2004

Lion's main enhances doxorubicin-induced apoptosis in human hepatocellular carcinoma cells.Nov 28, 2010

Parthenolide reverses doxorubicin resistance in human lung carcinoma A549 cells.Aug 13, 2013

Quercetin induces programmed cell death in human myeloid leukemia cells and their doxorubicin resistant variants. Jan 01, 2005

Resveratrol attenuates doxorubicin-induced cellular damage by modulating nitric oxide and apoptosis.Dec 06, 2010

Resveratrol induces cell-cycle disruption and programmed cell death in chemoresistant melanoma.Jul 01, 2010

Resveratrol reverses doxorubicin resistance in acute myeloid leukemia cells.Jan 01, 2008

Resveratrol sensitizes resistant leukemia cells to the the effects of anticancer drugs. Jan 01, 2006

Reversal effect of rosmarinic acid on multidrug resistance in gastric cancer cells.Dec 31, 2012

Review: Genetic and epigenetic modeling of the origins of multidrug-resistant cells in a human sarcoma cell line.Oct 15, 2005

Sufloraphane reduces doxorubicin resistance.Oct 10, 2006

Synergistic cytotoxicity of red beetroot (Beta vulgaris L.) extract with doxorubicin in human pancreatic, breast and prostate cancer cell lines.Dec 31, 2012

The association of sulforaphane-doxorubicin may therefore allow doxorubicin to be administered at lower doses, thereby reducing its potential toxicity.Jan 01, 2007

The mushroom Phellinus Linteus induces programmed cell death and arrests growth in human lung cancer cells. Feb 01, 2007

Theanine enhances the antitumor efficacy of chemotherapeutic agents. Dec 05, 2003

This data showed a synergistic inhibitory effect of manuka honey on doxorubicin-mediated apoptotic cell death in liver cancer cells.May 27, 2021

This reflects the significance of sesamol in ameliorating the deleterious effects associated with cancer chemotherapy.Jun 30, 2013

Turkey tail mushroom (C. versicolor) potentiates the anti-cancer activity of the chemotherapy drugs doxorubicin and etoposide against human promyelocytic leukemia cells. Jul 01, 2005

Drug: Doxorubicin

View the Evidence:
75 Abstracts with Drug: Doxorubicin Research