Drug: Oxaliplatin

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8 Diseases Researched for Drug: Oxaliplatin

Name	AC	CK	Focus
Colorectal Cancer	6	28
Cancers: Drug Resistant	3	5
Chemotherapy	1	2
Colon Cancer	2	2
Liver Metastasis From Colon Cancer	1	2
Chemotherapy-Induced Toxicity: Cisplatin	1	1
Colorectal Tumors	1	1
Ovarian Cancer	1	1

6 Substances Researched for Drug: Oxaliplatin

Name	AC	CK	Focus
Astragalus	1	20
Chinese Skullcap	1	20
Hedyotis corymbosa	1	20
Curcumin	5	7
Luteolin	1	2
Sulforaphane	1	1

7 Pharmacological Actions Researched for Drug: Oxaliplatin

Name	AC	CK	Focus
Chemosensitizer	5	7
Antiproliferative	4	6
Apoptotic	4	6
Antineoplastic Agents	2	3
Chemotherapeutic	1	2
Cell cycle arrest	1	1
Tumor Suppressor Protein p53 Upregulation	1	1

Research Articles 8
Cumulative Knowledge Score 12
Overall Research Rating GOOD

View the Evidence:
8 Abstracts with Drug: Oxaliplatin Research

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Specific combinations of traditional medicines appeared to produce higher contributions to tumor response rate than the TMs individually.Aug 05, 2015

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Pubmed Data : Integr Cancer Ther. 2015 Aug 6. Epub 2015 Aug 6. PMID: 26254190

Article Published Date : Aug 05, 2015

Study Type : Meta Analysis

Additional Links

Substances : Astragalus, Chinese Skullcap , Hedyotis corymbosa

Diseases : Colorectal Cancer

Additional Keywords : Drug: Oxaliplatin, Natural Substance/Drug Synergy

[+]

Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo.Sep 13, 2010

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Pubmed Data : Int J Cancer. 2010 Sep 13. Epub 2010 Sep 13. PMID: 20839263

Article Published Date : Sep 13, 2010

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Cancers: Drug Resistant, Chemotherapy, Colorectal Cancer

Pharmacological Actions : Chemosensitizer

Additional Keywords : Drug: Oxaliplatin, Drug Synergy

[+]

Luteolin could restore sensitivity of oxaliplatin resistant cell lines to chemotherapeutic drugs.Dec 31, 2013

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Asian Pac J Cancer Prev. 2014 ;15(6):2911-6. PMID: 24761924

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Substances : Luteolin

Diseases : Cancers: Drug Resistant, Colorectal Cancer

Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Drug: Oxaliplatin, Natural Substance/Drug Synergy

[+]

The addition of curcumin to FOLFOX based chemotherapy enhances efficacy in patient derived CRLM cultures.Aug 09, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cancer Lett. 2015 Aug 10 ;364(2):135-41. Epub 2015 May 12. PMID: 25979230

Article Published Date : Aug 09, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Colorectal Cancer, Liver Metastasis From Colon Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Chemotherapeutic

Additional Keywords : Cancer Stem Cells, Drug: Oxaliplatin, Natural Substance/Drug Synergy

[+]

Curcumin compares favorably with oxaliplatin as an antiproliferative in colorectal cell lines.Jul 01, 2007

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Pubmed Data : Int J Cancer. 2007 Jul 1;121(1):175-83. PMID: 17330230

Article Published Date : Jul 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Colorectal Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Drug: Oxaliplatin, Natural Substances Versus Drugs

[+]

Curcumin may contribute to overcoming chemoresistance of FOLFOX.-surviving colon cancer cells.Aug 01, 1989

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Pubmed Data : Vet Med (Praha). 1989 Aug;34(8):467-74. PMID: 20332435

Article Published Date : Aug 01, 1989

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Colon Cancer

Pharmacological Actions : Antiproliferative , Chemosensitizer

Additional Keywords : Drug: 5-flourouracil, Drug: Oxaliplatin

[+]

Curcumin may have chemosensitizing properties in the treatment of human ovarian cancer.Apr 01, 2009

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Pubmed Data : Cell Prolif. 2009 Apr;42(2):195-206. Epub 2009 Feb 18. PMID: 19236381

Article Published Date : Apr 01, 2009

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cancers: Drug Resistant, Chemotherapy-Induced Toxicity: Cisplatin, Ovarian Cancer

Pharmacological Actions : Antineoplastic Agents, Apoptotic, Cell cycle arrest, Chemosensitizer

Additional Keywords : Drug: Cisplatin, Drug: Oxaliplatin

[+]

Sulforaphane potentiates oxaliplatin-induced cell growth inhibition in colorectal cancer cells. Aug 06, 2010

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Pubmed Data : Cancer Chemother Pharmacol. 2010 Aug 6. Epub 2010 Aug 6. PMID: 20689952

Article Published Date : Aug 06, 2010

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane

Diseases : Colon Cancer, Colorectal Cancer, Colorectal Tumors

Pharmacological Actions : Chemosensitizer

Additional Keywords : Drug: Oxaliplatin, Drug-Plant-Vitamin Synergies

Research Articles 8
Cumulative Knowledge Score 12
Overall Research Rating GOOD

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