E6 Oncoprotein

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1 Problem Substances Researched for E6 Oncoprotein

Name	AC	CK	Focus
Benzo(a)pyrene	1	2

2 Diseases Researched for E6 Oncoprotein

Name	AC	CK	Focus
Cervical Cancer	8	11
Human Papillomavirus (HPV)	5	5

16 Substances Researched for E6 Oncoprotein

Name	AC	CK
Curcumin	4	5
Resveratrol	3	4
Pterostilbene	2	3
EGCG (Epigallocatechin gallate)	2	2
Flaxseed Oil	1	2
Artemisinin	1	1
Berberine	1	1
Ellagic Acid	1	1
Ferulic acid	1	1
Gingerol	1	1
Green Tea	1	1
Indole-3-Carbinol	1	1
Lactobacillus probiotics	1	1
Polyphenols	1	1
Silymarin	1	1
Ursolic Acid	1	1

12 Pharmacological Actions Researched for E6 Oncoprotein

Name	AC	CK
Antiproliferative	5	8
Chemopreventive	4	5
MicroRNA modulator	2	3
Anti-Apoptotic	1	2
Anti-metastatic	1	2
Anticarcinogenic Agents	2	2
Antineoplastic Agents	1	2
Antiviral Agents	2	2
Apoptotic	2	2
Tumor Suppressor Protein p53 Upregulation	2	2
Autophagy Inhibitors	1	1
Cell cycle arrest	1	1

Research Articles 10
Cumulative Knowledge Score 16
Overall Research Rating GOOD

View the Evidence:
10 Abstracts with E6 Oncoprotein Research

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Flax oil could be explored for its therapeutic potential in cervical cancer.Apr 04, 2019

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Pubmed Data : Prostaglandins Other Lipid Mediat. 2019 Apr 5. Epub 2019 Apr 5. PMID: 30959179

Article Published Date : Apr 04, 2019

Study Type : Animal Study

Additional Links

Substances : Flaxseed Oil

Diseases : Cervical Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Chemotherapeutic Synergy: Cisplatin, E6 Oncoprotein, E7 Oncoprotein

[+]

Nano curcumin may be an effective therapeutic modality for cervical cancer.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2016 ;6:20051. Epub 2016 Feb 3. PMID: 26837852

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Cervical Cancer

Pharmacological Actions : Anti-metastatic, Antiproliferative , MicroRNA modulator

Additional Keywords : E6 Oncoprotein

Problem Substances : Benzo(a)pyrene

[+]

Resveratrol and pterostilbene can serve as potential antineoplastic agents against HPV E6+ tumors.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Oncol. 2019 ;9:352. Epub 2019 May 9. PMID: 31143704

Article Published Date : Dec 31, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Pterostilbene, Resveratrol

Diseases : Cervical Cancer

Pharmacological Actions : Anti-Apoptotic, Antineoplastic Agents, Antiproliferative , Chemopreventive

Additional Keywords : E6 Oncoprotein

[+]

Curcumin and Ellagic acid show anti-HPV activity as evidenced by decrease in the HPV E6 oncoprotein on HeLa cells. Jun 30, 2016

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Pubmed Data : Biomed Pharmacother. 2016 Jul ;81:31-7. Epub 2016 Apr 8. PMID: 27261574

Article Published Date : Jun 30, 2016

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, Ellagic Acid

Diseases : Cervical Cancer, Human Papillomavirus (HPV)

Pharmacological Actions : Apoptotic, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : E6 Oncoprotein, Natural Substance Synergy

[+]

Curcumin-loaded OA400 nanoparticles could be considered as a treatment option in cervical cancer investigations.Nov 30, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Pharm Res. 2022 Dec ;21(1):e130762. Epub 2022 Oct 16. PMID: 36710992

Article Published Date : Nov 30, 2022

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cervical Cancer

Pharmacological Actions : Chemopreventive

Additional Keywords : E6 Oncoprotein

[+]

EGCG significantly inhibits HPV11 oncogenes expression in vitro. May 08, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Oncotarget. 2016 May 9. Epub 2016 May 9. PMID: 27175598

Article Published Date : May 08, 2016

Study Type : In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Human Papillomavirus (HPV)

Pharmacological Actions : MicroRNA modulator

Additional Keywords : E6 Oncoprotein, E7 Oncoprotein

[+]

Green tea polyphenols cause apoptosis and autophagy in HPV-16 subgene-immortalized human cervical epithelial cells.Jun 29, 2022

Click here to read the entire abstract

Pubmed Data : Nutr Cancer. 2022 Jun 30:1-10. Epub 2022 Jun 30. PMID: 35770917

Article Published Date : Jun 29, 2022

Study Type : In Vitro Study

Additional Links

Substances : Green Tea, Polyphenols

Diseases : Cervical Cancer, Human Papillomavirus (HPV)

Pharmacological Actions : Anticarcinogenic Agents, Antiviral Agents

Additional Keywords : E6 Oncoprotein, E7 Oncoprotein

[+]

Lactobacilli culture supernatants can decrease expression of ATG14 and BECN1 as well as the HPV E6 oncogene.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Cell J. 2016 ;17(4):601-7. Epub 2016 Jan 17. PMID: 26862519

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Lactobacillus probiotics

Diseases : Cervical Cancer, Human Papillomavirus (HPV)

Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Autophagy Inhibitors, Chemopreventive

Additional Keywords : E6 Oncoprotein, Gene Expression Regulation

[+]

Resveratrol and pterostilbene exhibit anticancer properties involving the downregulation of HPV oncoprotein E6 in cervical cancer cells.Feb 20, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2018 Feb 21 ;10(2). Epub 2018 Feb 21. PMID: 29485619

Article Published Date : Feb 20, 2018

Study Type : In Vitro Study

Additional Links

Substances : Pterostilbene, Resveratrol

Diseases : Cervical Cancer

Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : E6 Oncoprotein

[+]

These natural inhibitors have been shown to block HPV infection and inhibition of HPV oncoproteins. May 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Genomics Inform. 2015 Jun ;13(2):60-7. Epub 2015 Jun 30. PMID: 26175664

Article Published Date : May 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Artemisinin, Berberine, Curcumin, EGCG (Epigallocatechin gallate), Ferulic acid, Gingerol , Indole-3-Carbinol, Resveratrol, Silymarin, Ursolic Acid

Diseases : Human Papillomavirus (HPV)

Pharmacological Actions : Antiviral Agents, Chemopreventive

Additional Keywords : E6 Oncoprotein, Risk Reduction

Research Articles 10
Cumulative Knowledge Score 16
Overall Research Rating GOOD

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 10 Abstracts with E6 Oncoprotein Research

Limited to Members Only

Currently Available Sorting Options

Flax oil could be explored for its therapeutic potential in cervical cancer.Apr 04, 2019

Nano curcumin may be an effective therapeutic modality for cervical cancer.Dec 31, 2015

Resveratrol and pterostilbene can serve as potential antineoplastic agents against HPV E6+ tumors.Dec 31, 2018

Curcumin and Ellagic acid show anti-HPV activity as evidenced by decrease in the HPV E6 oncoprotein on HeLa cells. Jun 30, 2016

Curcumin-loaded OA400 nanoparticles could be considered as a treatment option in cervical cancer investigations.Nov 30, 2022

EGCG significantly inhibits HPV11 oncogenes expression in vitro. May 08, 2016

Green tea polyphenols cause apoptosis and autophagy in HPV-16 subgene-immortalized human cervical epithelial cells.Jun 29, 2022

Lactobacilli culture supernatants can decrease expression of ATG14 and BECN1 as well as the HPV E6 oncogene.Dec 31, 2015

Resveratrol and pterostilbene exhibit anticancer properties involving the downregulation of HPV oncoprotein E6 in cervical cancer cells.Feb 20, 2018

These natural inhibitors have been shown to block HPV infection and inhibition of HPV oncoproteins. May 31, 2015

Print Options

E6 Oncoprotein

View the Evidence:
10 Abstracts with E6 Oncoprotein Research