Endocannabinoid System

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4 Problem Substances Researched for Endocannabinoid System
NameACCKFocus
Bisphenol A 417Locked
Acetaminophen110Locked
Paracetamol110Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)11Locked
59 Diseases Researched for Endocannabinoid System
NameACCKFocus
Endocannabinoid Disorders422Locked
Bisphenol Toxicity417Locked
Depression416Locked
Autism Spectrum Disorders215Locked
Inflammation312Locked
Acetaminophen (Tylenol) Toxicity 110Locked
Anorexia110Locked
Attention Deficit Hyperactivity Disorder110Locked
Coronary Artery Disease110Locked
Dravet syndrome110Locked
Insulin Resistance110Locked
Pregnancy Complications110Locked
Cancers: All45Locked
Colon Cancer35Locked
Colorectal Cancer15Locked
Fatty Liver15Locked
Hepatic Steatosis15Locked
Post-Traumatic Stress Disorders (PTSD)45Locked
Neuropathic Pain24Locked
Alzheimer's Disease33Locked
Epilepsy23Locked
Multiple Sclerosis33Locked
Anxiety12Locked
Brain Ischemia12Locked
Cancer Metastasis12Locked
Diabetes Mellitus: Type 1: Prevention12Locked
Gastrointestinal Inflammation12Locked
High Fat Diet12Locked
Hypertension12Locked
Lipopolysaccharide-Induced Toxicity12Locked
Melanoma: Metastasis12Locked
Migraines12Locked
Neonatal Stroke12Locked
Obesity12Locked
Schizophrenia22Locked
Stroke: Attenuation/Recovery 12Locked
Acne11Locked
Alcohol Toxicity 11Locked
Allergies11Locked
Anxiety Disorders11Locked
Autoimmune Diseases11Locked
Chemotherapy-Induced Nausea11Locked
Cirrhosis11Locked
Dermatitis11Locked
Dry Skin 11Locked
Dysbiosis11Locked
Huntington Disease11Locked
Inflammatory Bowel Diseases11Locked
Irritable Bowel Syndrome11Locked
Osteoporosis11Locked
Parkinson's Disease11Locked
Prion Diseases11Locked
Psoriasis11Locked
Psychoses11Locked
Psychotic Disorders11Locked
Seborrheic Keratosis11Locked
Skin Cancer11Locked
Spinal Cord Injuries11Locked
Stroke11Locked
17 Substances Researched for Endocannabinoid System
NameACCKFocus
Cannabinoids 1323Locked
Cannabidiol1122Locked
Endocannabinoids621Locked
Cannabis716Locked
Anandamide313Locked
Flaxseed110Locked
Delta-tetrahydrocannabinol (THC)88Locked
Gc protein-derived macrophage activating factor (GcMAF)15Locked
Beta-Caryophyllene12Locked
Cannabinoids: Synthetic12Locked
Crocin12Locked
Grape Seed Extract12Locked
Lysergic Acid Diethylamide (LSD)12Locked
Olive Oil12Locked
Melatonin11Locked
Nutmeg11Locked
Resveratrol11Locked
5 Therapeutic Actions Researched for Endocannabinoid System
NameACCKFocus
Exercise212Locked
Dietary Modification: Mediterranean Diet110Locked
Exercise: Cycling110Locked
Electroacupuncture24Locked
Exercise: Resistance Training12Locked
28 Pharmacological Actions Researched for Endocannabinoid System
NameACCKFocus
Anti-Inflammatory Agents1131Locked
Gastrointestinal Agents415Locked
Antidepressive Agents314Locked
Brain-derived neurotrophic factor modulator110Locked
Cardioprotective110Locked
Insulin Sensitizers110Locked
Immunomodulatory27Locked
Analgesics46Locked
Antiproliferative 46Locked
Anticarcinogenic Agents34Locked
Antinoceceptive 24Locked
Chemopreventive24Locked
Neuroprotective Agents34Locked
Anti-Anxiety Agents23Locked
Antineoplastic Agents23Locked
Antioxidants33Locked
Anti-metastatic22Locked
Anticonvulsants12Locked
Apoptotic22Locked
Neurogenesis12Locked
Vasoprotective12Locked
Angiogenesis Inhibitors11Locked
Anti-Fibrotic11Locked
Autophagy Up-regulation11Locked
Cannabinoid Receptor Antagonist/Inverse Agonist11Locked
Cell cycle arrest11Locked
Gastroprotective11Locked
Hepatoprotective11Locked

View the Evidence:
56 Abstracts with Endocannabinoid System Research

[+]

Acetaminophen use for fever in children associated with autism spectrum disorder.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Autism Open Access. 2016 Apr ;6(2). Epub 2016 Mar 28. PMID: 27695658
Article Published Date : Mar 31, 2016
Study Type : Human Study
Additional Links
Diseases : Acetaminophen (Tylenol) Toxicity , Autism Spectrum Disorders
Additional Keywords : Endocannabinoid System
Problem Substances : Acetaminophen, Paracetamol
[+]

Based on obtained results it can be hypothesized that BPA may induce adverse pregnancy outcomes by acting on endocannabinoid system.Mar 29, 2018

Pubmed Data : Chemosphere. 2018 Mar 30 ;203:387-392. Epub 2018 Mar 30. PMID: 29627605
Article Published Date : Mar 29, 2018
Study Type : Human Study
Additional Links
Diseases : Bisphenol Toxicity, Pregnancy Complications
Additional Keywords : Endocannabinoid System, Risk Factors
Problem Substances : Bisphenol A
[+]

Cannabidiol could be useful in Dravet syndrome treatments. Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacol Res Perspect. 2016 Apr ;4(2):e00220. Epub 2016 Mar 5. PMID: 27069631
Article Published Date : Mar 31, 2016
Study Type : Human Study
Additional Links
Substances : Cannabidiol
Diseases : Dravet syndrome, Endocannabinoid Disorders
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Endocannabinoid System
[+]

Endocannabinoids and endocannabinoid related compounds are involved in food related reward and suggest a dysregulation of their physiology in anorexia nervosa.Jan 31, 2015

Pubmed Data : Am J Clin Nutr. 2015 Feb ;101(2):262-9. Epub 2014 Dec 10. PMID: 25646322
Article Published Date : Jan 31, 2015
Study Type : Human Study
Additional Links
Substances : Anandamide, Endocannabinoids
Diseases : Anorexia, Endocannabinoid Disorders
Additional Keywords : Diseases that are Linked, Endocannabinoid System
[+]

Flaxseed oil may be considered a promising agent with cardioprotective properties.May 04, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genes Nutr. 2020 May 5 ;15(1):9. Epub 2020 May 5. PMID: 32370762
Article Published Date : May 04, 2020
Study Type : Human Study
Additional Links
Substances : Flaxseed
Diseases : Coronary Artery Disease
Pharmacological Actions : Cardioprotective
Additional Keywords : Endocannabinoid System
[+]

Intense exercise increases circulating endocannabinoid and BDNF levels in humans-possible implications for reward and depression.May 31, 2012

Pubmed Data : Psychoneuroendocrinology. 2012 Jun ;37(6):844-51. Epub 2011 Oct 24. PMID: 22029953
Article Published Date : May 31, 2012
Study Type : Human Study
Additional Links
Diseases : Depression
Therapeutic Actions : Exercise, Exercise: Cycling
Pharmacological Actions : Antidepressive Agents, Brain-derived neurotrophic factor modulator
Additional Keywords : Endocannabinoid System
[+]

Mediterranean diet consumption affects the endocannabinoid system in overweight and obese subjects.Mar 23, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Nutr. 2021 Mar 24. Epub 2021 Mar 24. PMID: 33763720
Article Published Date : Mar 23, 2021
Study Type : Human Study
Additional Links
Diseases : Inflammation, Insulin Resistance
Therapeutic Actions : Dietary Modification: Mediterranean Diet
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Insulin Sensitizers
Additional Keywords : Endocannabinoid System
[+]

This study provides preliminary evidence supporting the self-medication theory of cannabis use in ADHD.May 29, 2017

Pubmed Data : Eur Neuropsychopharmacol. 2017 May 30. Epub 2017 May 30. PMID: 28576350
Article Published Date : May 29, 2017
Study Type : Human Study
Additional Links
Substances : Cannabinoids , Cannabis
Diseases : Attention Deficit Hyperactivity Disorder
Additional Keywords : Endocannabinoid System, Plant Extracts
[+]

Bisphenol A is able to produce hepatosteatosis in zebrafish and human hepatocytes by up-regulating the endocannabinoid system.Apr 30, 2016

Pubmed Data : Endocrinology. 2016 May ;157(5):1751-63. Epub 2016 Mar 25. PMID: 27014939
Article Published Date : Apr 30, 2016
Study Type : Animal Study, Human In Vitro
Additional Links
Diseases : Bisphenol Toxicity, Fatty Liver, Hepatic Steatosis
Additional Keywords : Endocannabinoid System
Problem Substances : Bisphenol A
[+]

Endocannabinoid and ceramide levels are altered in patients with colorectal cancer.Jun 30, 2015

Pubmed Data : Oncol Rep. 2015 Jul ;34(1):447-54. Epub 2015 May 12. PMID: 25975960
Article Published Date : Jun 30, 2015
Study Type : Human In Vitro
Additional Links
Substances : Endocannabinoids
Diseases : Colorectal Cancer
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System
[+]

This study demonstrates a biomolecular effect of GcMAF in BMDMs from autistic patients, providing further evidence for a positive use of this molecule in autism treatment.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2014 ;11:78. Epub 2014 Apr 17. PMID: 24739187
Article Published Date : Dec 31, 2013
Study Type : Human In Vitro
Additional Links
Substances : Gc protein-derived macrophage activating factor (GcMAF)
Diseases : Autism Spectrum Disorders
Pharmacological Actions : Immunomodulatory
Additional Keywords : Endocannabinoid System
[+]

Thymol modulates the endocannabinoid system and gut chemosensing of weaning pigsAug 11, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Vet Res. 2020 Aug 12 ;16(1):289. Epub 2020 Aug 12. PMID: 32787931
Article Published Date : Aug 11, 2020
Study Type : Animal Study
Additional Links
Diseases : Gastrointestinal Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents
Additional Keywords : Endocannabinoid System
[+]

A single session of resistance exercise activates the endocannabinoid system to induce antinociception.Aug 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anesth Analg. 2014 Sep ;119(3):702-15. PMID: 24977916
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Therapeutic Actions : Exercise: Resistance Training
Pharmacological Actions : Antinoceceptive
Additional Keywords : Endocannabinoid System
[+]

Antidepressant-like effects of β-caryophyllene on restraint plus stress-induced depression.Feb 16, 2020

Pubmed Data : Behav Brain Res. 2020 Feb 17 ;380:112439. Epub 2019 Dec 17. PMID: 31862467
Article Published Date : Feb 16, 2020
Study Type : Animal Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Depression, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents
Additional Keywords : Endocannabinoid System
[+]

Cannabidiol protected DNA from oxidative damage, increased endocannabinoid levels and reduced cell proliferation.Jul 31, 2012

Pubmed Data : J Mol Med (Berl). 2012 Aug ;90(8):925-34. Epub 2012 Jan 10. PMID: 22231745
Article Published Date : Jul 31, 2012
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Colon Cancer
Pharmacological Actions : Anticarcinogenic Agents, Antineoplastic Agents, Antiproliferative , Chemopreventive
Additional Keywords : Endocannabinoid System
[+]

CBD treatment has vasoprotective effects in hypertension.Oct 30, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2021 Oct 31 ;14(11). Epub 2021 Oct 31. PMID: 34832902
Article Published Date : Oct 30, 2021
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Hypertension
Pharmacological Actions : Vasoprotective
Additional Keywords : Endocannabinoid System
[+]

Chronic exercise reverses some alterations caused by a high fat diet.Feb 14, 2016

Pubmed Data : J Physiol Biochem. 2016 Feb 15. Epub 2016 Feb 15. PMID: 26880264
Article Published Date : Feb 14, 2016
Study Type : Animal Study
Additional Links
Diseases : High Fat Diet, Obesity
Therapeutic Actions : Exercise
Additional Keywords : Endocannabinoid System
[+]

Combined-acupoint electroacupuncture induces better analgesia.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Plast. 2022 ;2022:7670629. Epub 2022 Sep 15. PMID: 36160326
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Diseases : Neuropathic Pain
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Analgesics
Additional Keywords : Endocannabinoid System
[+]

Crocin has significant analgesic effects that are probably mediated by an endocannabinoid mechanism.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Exp Pharmacol. 2020 ;12:97-106. Epub 2020 Apr 28. PMID: 32431552
Article Published Date : Dec 31, 2019
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Neuropathic Pain
Pharmacological Actions : Analgesics
Additional Keywords : Endocannabinoid System
[+]

Early intervention with electroacupuncture prevents PTSD-like behaviors.Mar 31, 2019

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2019 Apr 1 ;93:171-181. Epub 2019 Apr 1. PMID: 30946940
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Diseases : Post-Traumatic Stress Disorders (PTSD)
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Endocannabinoid System
[+]

Effects of repeated lysergic acid diethylamide (LSD) on the mouse brain endocannabinoidome and gut microbiome.Feb 28, 2023

Pubmed Data : Br J Pharmacol. 2023 Mar ;180(6):721-739. Epub 2022 Dec 12. PMID: 36316276
Article Published Date : Feb 28, 2023
Study Type : Animal Study
Additional Links
Substances : Lysergic Acid Diethylamide (LSD)
Diseases : Anxiety, Depression
Pharmacological Actions : Anti-Anxiety Agents, Antidepressive Agents, Gastrointestinal Agents
Additional Keywords : Endocannabinoid System
[+]

Endocannabinoid system acts as a regulator of immune homeostasis in the gutApr 23, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 2017 Apr 24. Epub 2017 Apr 24. PMID: 28439004
Article Published Date : Apr 23, 2017
Study Type : Animal Study
Additional Links
Substances : Anandamide, Endocannabinoids
Diseases : Diabetes Mellitus: Type 1: Prevention
Pharmacological Actions : Immunomodulatory
Additional Keywords : Endocannabinoid System
[+]

Extravirgin olive oil up-regulates CB₁ tumor suppressor gene in human colon cancer cells.Feb 28, 2015

Pubmed Data : J Nutr Biochem. 2015 Mar ;26(3):250-8. Epub 2014 Dec 3. PMID: 25533906
Article Published Date : Feb 28, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Olive Oil
Diseases : Colon Cancer
Pharmacological Actions : Antiproliferative , Chemopreventive
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System, Epigenetic Modification In Cancer, Plant Extracts
[+]

Grape seed extract may be beneficial as a complementary migraine therapeutic.Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pain Res (Lausanne). 2022 ;3:809352. Epub 2022 Jan 27. PMID: 35295808
Article Published Date : Dec 31, 2021
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Migraines
Pharmacological Actions : Antinoceceptive
Additional Keywords : Endocannabinoid System
[+]

Short-term potentiation of the eCB system might modify the epileptogenic disease process in patients with a progressive course of epilepsy.May 31, 2015

Pubmed Data : Pharmacol Rep. 2015 Jun ;67(3):501-3. Epub 2014 Dec 17. PMID: 25933961
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Cannabinoids: Synthetic
Diseases : Epilepsy
Pharmacological Actions : Anticonvulsants
Additional Keywords : Endocannabinoid System
[+]

The activation of the endocannabinoid system promotes white and gray matter recovery after neonatal HI injury.Nov 30, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Stroke. 2010 Dec ;41(12):2956-64. PMID: 21115947
Article Published Date : Nov 30, 2010
Study Type : Animal Study
Additional Links
Substances : Cannabinoids
Diseases : Brain Ischemia, Neonatal Stroke, Stroke: Attenuation/Recovery
Pharmacological Actions : Neurogenesis
Additional Keywords : Endocannabinoid System, Neuro-repair
[+]

The endocannabinoid system was subject to cancer-associated regulations to an extent that led to measurable changes in circulating endocannabinoid levels.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncoscience. 2014 ;1(4):272-82. Epub 2014 Apr 30. PMID: 25594019
Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Substances : Endocannabinoids
Diseases : Cancer Metastasis, Cancers: All, Melanoma: Metastasis
Additional Keywords : Endocannabinoid System
[+]

These findings suggest that dysregulation in the endocannabinoid system is implicated in the pathogenesis of depression.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurotox Res. 2017 Apr ;31(3):421-435. Epub 2017 Feb 28. PMID: 28247204
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Depression
Additional Keywords : Endocannabinoid System
[+]

A growing amount of experimental data imply possible exploitation of cannabinoids in cancer therapy. Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Onco Targets Ther. 2016 ;9:4323-36. Epub 2016 Jul 18. PMID: 27486335
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)
Diseases : Cancers: All
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative , Apoptotic, Autophagy Up-regulation, Cell cycle arrest
Additional Keywords : Endocannabinoid System
[+]

A review of the role of cannabinoids on esophageal function.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cannabis Cannabinoid Res. 2017 ;2(1):252-258. Epub 2017 Oct 1. PMID: 29098187
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Substances : Cannabinoids
Additional Keywords : Endocannabinoid System
[+]

Alteration of the endocannabinoid system in mouse brain during prion disease.Mar 16, 2011

Pubmed Data : Neuroscience. 2011 Mar 17 ;177:292-7. Epub 2010 Dec 31. PMID: 21195746
Article Published Date : Mar 16, 2011
Study Type : In Vitro Study
Additional Links
Diseases : Prion Diseases
Additional Keywords : Endocannabinoid System
[+]

Bisphenol A deranges the endocannabinoid system of primary sertoli cells.Nov 25, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2020 Nov 26 ;21(23). Epub 2020 Nov 26. PMID: 33256105
Article Published Date : Nov 25, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity, Endocannabinoid Disorders
Additional Keywords : Endocannabinoid System
Problem Substances : Bisphenol A
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Cannabidiol alters the functionality of neutrophils implications in the refractory epilepsy treatment.Mar 04, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2021 Mar 5 ;14(3). Epub 2021 Mar 5. PMID: 33807975
Article Published Date : Mar 04, 2021
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol
Diseases : Epilepsy
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Endocannabinoid System
[+]

Cannabidiol shows great promise for the treatment of psychosis.May 27, 2016

Pubmed Data : J Psychiatr Res. 2016 May 28 ;80:14-21. Epub 2016 May 28. PMID: 27267317
Article Published Date : May 27, 2016
Study Type : Review
Additional Links
Substances : Cannabidiol
Diseases : Psychoses, Schizophrenia
Additional Keywords : Endocannabinoid System
[+]

Cannabinoids can activate TRPA1, TRPV1 and TRPV2.Jul 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Br J Pharmacol. 2011 Aug ;163(7):1479-94. PMID: 21175579
Article Published Date : Jul 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Cannabidiol, Cannabinoids , Cannabis, Delta-tetrahydrocannabinol (THC)
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents
Additional Keywords : Endocannabinoid System, Plant Extracts
[+]

Cannabis and cannabinoids can protect the gastric mucosa against noxious challenge.Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Asian Pac J Trop Med. 2016 May ;9(5):413-9. Epub 2016 Apr 15. PMID: 27261847
Article Published Date : Apr 30, 2016
Study Type : Review
Additional Links
Substances : Cannabinoids , Cannabis, Delta-tetrahydrocannabinol (THC)
Diseases : Alcohol Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Gastrointestinal Agents, Gastroprotective
Additional Keywords : Endocannabinoid System
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Endocannabinoid system as therapeutic target of PTSD.Mar 08, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Life (Basel). 2021 Mar 9 ;11(3). Epub 2021 Mar 9. PMID: 33803374
Article Published Date : Mar 08, 2021
Study Type : Review
Additional Links
Substances : Cannabidiol, Delta-tetrahydrocannabinol (THC)
Diseases : Post-Traumatic Stress Disorders (PTSD)
Pharmacological Actions : Analgesics
Additional Keywords : Endocannabinoid System
[+]

Endocannabinoid system in irritable bowel syndrome and cannabis as a therapy.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Complement Ther Med. 2020 Jan ;48:102242. Epub 2019 Nov 13. PMID: 31987224
Article Published Date : Dec 31, 2019
Study Type : Review
Additional Links
Substances : Cannabis
Diseases : Irritable Bowel Syndrome
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Endocannabinoid System
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Evidence is gathering that manipulating the endocannabinoid system can have beneficial effects in inflammatory bowel disease.Dec 31, 2013

Pubmed Data : Dig Dis. 2014 ;32(4):468-74. Epub 2014 Jun 23. PMID: 24969296
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Substances : Cannabinoids , Cannabis
Diseases : Inflammatory Bowel Diseases
Additional Keywords : Endocannabinoid System
[+]

Melatonin and resveratrol alleviate molecular and metabolic toxicity induced by Bisphenol A in endometrial organoids.Jun 04, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Reprod Toxicol. 2024 Jun 5 ;128:108628. Epub 2024 Jun 5. PMID: 38848930
Article Published Date : Jun 04, 2024
Study Type : In Vitro Study
Additional Links
Substances : Melatonin, Resveratrol
Diseases : Bisphenol Toxicity
Additional Keywords : Endocannabinoid System
Problem Substances : Bisphenol A
[+]

Recent evidence suggests a role for the endocannabinoid system in modulating chemotherapy-induced nausea and vomiting.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2016 ;7:221. Epub 2016 Jul 26. PMID: 27507945
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Cannabinoids , Delta-tetrahydrocannabinol (THC)
Diseases : Chemotherapy-Induced Nausea
Additional Keywords : Endocannabinoid System
[+]

Role of the endocannabinoid system in vertebrates.May 16, 2017

Pubmed Data : Dev Growth Differ. 2017 May 17. Epub 2017 May 17. PMID: 28516445
Article Published Date : May 16, 2017
Study Type : Review
Additional Links
Substances : Cannabinoids
Additional Keywords : Endocannabinoid System
[+]

Roles of Cannabidiol in the treatment and prevention of Alzheimer's disease by multi-target actions.Mar 30, 2021

Pubmed Data : Mini Rev Med Chem. 2021 Mar 31. Epub 2021 Mar 31. PMID: 33797364
Article Published Date : Mar 30, 2021
Study Type : Review
Additional Links
Substances : Cannabidiol
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
Additional Keywords : Endocannabinoid System
[+]

Several components of the endocannabinoid system have therapeutic potential in cirrhosis.Jun 08, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicines (Basel). 2018 Jun 9 ;5(2). Epub 2018 Jun 9. PMID: 29890719
Article Published Date : Jun 08, 2018
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Cirrhosis
Pharmacological Actions : Anti-Fibrotic, Hepatoprotective
Additional Keywords : Endocannabinoid System
[+]

Studies indicate that the cannabinoid system is impaired in different psychotic disorders.Feb 03, 2016

Pubmed Data : Curr Top Med Chem. 2016 Feb 4. Epub 2016 Feb 4. PMID: 26845552
Article Published Date : Feb 03, 2016
Study Type : Review
Additional Links
Substances : Delta-tetrahydrocannabinol (THC)
Diseases : Psychotic Disorders, Schizophrenia
Additional Keywords : Endocannabinoid System
[+]

Targeting the endocannabinoid system represents an attractive and novel approach to the treatment of anxiety-related disorders.Sep 29, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Basic Clin Physiol Pharmacol. 2015 Sep 30. Epub 2015 Sep 30. PMID: 26426887
Article Published Date : Sep 29, 2015
Study Type : Review
Additional Links
Substances : Cannabis
Diseases : Anxiety Disorders, Post-Traumatic Stress Disorders (PTSD)
Pharmacological Actions : Anti-Anxiety Agents
Additional Keywords : Endocannabinoid System
[+]

The endocannabinoid system and its modulation by cannabidiol.May 31, 2019

Pubmed Data : Altern Ther Health Med. 2019 Jun ;25(S2):6-14. PMID: 31202198
Article Published Date : May 31, 2019
Study Type : Review
Additional Links
Substances : Cannabidiol
Diseases : Autoimmune Diseases, Cancers: All, Osteoporosis, Spinal Cord Injuries, Stroke
Additional Keywords : Endocannabinoid System
[+]

The endocannabinoid system might influence the generation of dream experiences.Feb 22, 2017

Pubmed Data : CNS Neurol Disord Drug Targets. 2017 Feb 23. Epub 2017 Feb 23. PMID: 28240187
Article Published Date : Feb 22, 2017
Study Type : Review
Additional Links
Substances : Cannabinoids
Diseases : Post-Traumatic Stress Disorders (PTSD)
Additional Keywords : Endocannabinoid System
[+]

The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cellsJul 01, 2010

Pubmed Data : Int J Oncol. 2010 Jul;37(1):187-93. PMID: 20514410
Article Published Date : Jul 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Anandamide
Diseases : Colon Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Endocannabinoid System, Endogenous Cannabinoid
[+]

The intestinal flora may affect the pathogenesis of multiple sclerosis.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Immunol Res. 2017 ;2017:7904821. Epub 2017 Feb 20. PMID: 28316999
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Diseases : Dysbiosis, Inflammation, Multiple Sclerosis
Additional Keywords : Endocannabinoid System, Microbiota
[+]

The manipulation of the endogenous cannabinoid system offers a potential approach to the treatment of Alzheimer's disease.Jul 01, 2018

Pubmed Data : Curr Neuropharmacol. 2018 Jul 2. Epub 2018 Jul 2. PMID: 29962346
Article Published Date : Jul 01, 2018
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Endocannabinoid System
[+]

This article reviews the most important current data involving the endocannabinoid system in relation to human diseases.Mar 31, 2017

Pubmed Data : Expert Rev Clin Pharmacol. 2017 Apr ;10(4):443-455. Epub 2017 Feb 28. PMID: 28276775
Article Published Date : Mar 31, 2017
Study Type : Review
Additional Links
Substances : Cannabidiol, Cannabinoids , Delta-tetrahydrocannabinol (THC)
Diseases : Alzheimer's Disease, Huntington Disease, Multiple Sclerosis, Parkinson's Disease
Additional Keywords : Endocannabinoid System, Plant Extracts
[+]

This review critically discusses the pharmacology of CB receptor activation as a novel therapeutic anticancer strategyJun 30, 2009

Pubmed Data : J Pharm Pharmacol. 2009 Jul ;61(7):839-53. PMID: 19589225
Article Published Date : Jun 30, 2009
Study Type : Review
Additional Links
Substances : Cannabinoids , Endocannabinoids
Diseases : Cancers: All
Pharmacological Actions : Angiogenesis Inhibitors, Anti-Inflammatory Agents, Anti-metastatic, Anticarcinogenic Agents, Antineoplastic Agents, Antiproliferative
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System
[+]

This review discusses how the endocannabinoid system can help treat diseases of the skin.Jul 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Trends Pharmacol Sci. 2009 Aug ;30(8):411-20. Epub 2009 Jul 14. PMID: 19608284
Article Published Date : Jul 31, 2009
Study Type : Review
Additional Links
Substances : Endocannabinoids
Diseases : Acne, Allergies, Dermatitis, Dry Skin , Inflammation, Psoriasis, Seborrheic Keratosis, Skin Cancer
Pharmacological Actions : Anticarcinogenic Agents, Cannabinoid Receptor Antagonist/Inverse Agonist
Additional Keywords : Cannabinoid Receptors, Endocannabinoid System
[+]

This reviews the evidence, efficacy and effectiveness of THC-CBD oromucosal spray in symptom management for patients with spasticity due to MS.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ther Adv Neurol Disord. 2016 Jan ;9(1):9-30. PMID: 26788128
Article Published Date : Dec 31, 2015
Study Type : Review
Additional Links
Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)
Diseases : Multiple Sclerosis
Additional Keywords : Endocannabinoid System
[+]

This study provides the first piece of evidence that nutmeg interacts with the endocannabinoid system.Jun 13, 2016

Pubmed Data : Pharm Biol. 2016 Jun 14:1-6. Epub 2016 Jun 14. PMID: 27296774
Article Published Date : Jun 13, 2016
Study Type : In Vitro Study
Additional Links
Substances : Nutmeg
Diseases : Endocannabinoid Disorders
Additional Keywords : Endocannabinoid System, Plant Extracts

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