Gene Expression

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34 Problem Substances Researched for Gene Expression
NameACCKFocus
Bisphenol A 2458Locked
Statin Drugs314Locked
Bisphenol S612Locked
Antidepressants110Locked
Sodium Fluoride39Locked
Glyphosate47Locked
Pesticides47Locked
Triclosan27Locked
Octylphenol 15Locked
Radon15Locked
High Fructose Corn Syrup24Locked
Aluminum33Locked
Oseltamivir (trade name Tamiflu)13Locked
Phthalates23Locked
Artificial Sweeteners12Locked
Aspartame12Locked
Bisphenol P12Locked
Chlorpyrifos12Locked
Electronic Cigarettes12Locked
Fluoride12Locked
Fluoxetine (trade name Prozac) 12Locked
Lead12Locked
Organophosphate Pesticides12Locked
Propylene Glycol12Locked
Saccharin12Locked
Simvastatin12Locked
Sugar Sweetened Beverages12Locked
Acetaminophen11Locked
Benzo(a)pyrene11Locked
Ethanol11Locked
Heavy Metals11Locked
Monosodium Glutamate (MSG)11Locked
Oral Contraceptives11Locked
Vaccine Adjuvants11Locked
81 Diseases Researched for Gene Expression
NameACCKFocus
Bisphenol Toxicity1646Locked
Prenatal Chemical Exposures1044Locked
Autism Spectrum Disorders423Locked
Vitamin D Deficiency321Locked
Breast Cancer516Locked
Statin-Induced Pathologies314Locked
Infertility: Female313Locked
Depression211Locked
Air Pollution Linked Toxicity110Locked
Cholesterol: LDL/HDL ratio110Locked
Depressive Disorder110Locked
Multiple Sclerosis110Locked
Sleep Disorders110Locked
Circadian Dysregulation38Locked
Bisphenol-A Toxicity47Locked
Lung Cancer37Locked
Radiation Induced Illness27Locked
Fetal Origin of Adult Disease36Locked
Glyphosate Toxicity36Locked
Cancer Metastasis15Locked
Fluoride Toxicity 15Locked
Hypoxia15Locked
Brain Inflammation 24Locked
Inflammation34Locked
Obesity34Locked
Pesticide Toxicity 24Locked
Psychiatric Disorders24Locked
Alcohol Toxicity 23Locked
Aluminum Toxicity 33Locked
Autoimmune Diseases23Locked
Hepatic Steatosis23Locked
Acinetobacter baumannii infection12Locked
Alcoholism12Locked
Atherosclerosis12Locked
Autism22Locked
Bee Colony Collapse12Locked
Cancers: All22Locked
Cardiovascular Diseases12Locked
Cholera22Locked
DNA damage12Locked
Dysbiosis12Locked
Encephalomyelitis12Locked
Female Reproductive Development Abnormalities12Locked
Fructose-Induced Toxicity 12Locked
Glycemia12Locked
Hepatitis B 12Locked
High Fat Diet12Locked
High Fructose Diet12Locked
High Sugar Diet12Locked
Infertility12Locked
Inflammatory Bowel Diseases12Locked
Liver Cancer12Locked
Metabolic Diseases12Locked
Mineral Deficiencies: Selenium12Locked
Morphine Tolerance/Dependence12Locked
Multiple Sclerosis: Relapsing-Remitting 12Locked
Myopathy12Locked
Neuropathic Pain12Locked
Nicotine/Tobacco Toxicity 12Locked
Phthalate Toxicity12Locked
Vitamin A Deficiency12Locked
Vitamin B 12 Deficiency12Locked
Vitamin C Deficiency12Locked
Vitamin E Deficiency12Locked
Alzheimer's Disease11Locked
Bisphenol S Toxicity11Locked
Carcinoma: Non-Small-Cell Lung11Locked
Diabetes Mellitus: Type 211Locked
Gram-Negative Bacterial Infections11Locked
Gram-Positive Bacterial Infections11Locked
H1N1 Infection11Locked
HIV Infections11Locked
Herpes Simplex Virus Type 111Locked
Herpes Simplex Virus Type 211Locked
Influenza A11Locked
Listeria Infections11Locked
Melanoma11Locked
Neuroblastoma11Locked
Neurodegenerative Diseases11Locked
Oxidative Stress11Locked
Wound Healing11Locked
5 Problematic Actions Researched for Gene Expression
NameACCKFocus
Electromagnetic Field Harms110Locked
5G Millimeter Wave Radiation38Locked
Western Diet12Locked
Chemotherapy11Locked
Vaccination: All11Locked
11 Adverse Pharmacological Actions Researched for Gene Expression
NameACCKFocus
Inflammatory48Locked
Neurotoxic48Locked
Anti-Fertility24Locked
Cardiotoxic24Locked
Hepatotoxic24Locked
Atherogenic12Locked
Diabetogenic12Locked
Immunotoxic12Locked
Interleukin-6 up-regulation12Locked
Renotoxic12Locked
Tumor necrosis factorα (TNFα) up-regulation12Locked
33 Substances Researched for Gene Expression
NameACCKFocus
Vitamin D321Locked
Curcumin46Locked
Resveratrol24Locked
Apigenin12Locked
Boron12Locked
Cannabidiol12Locked
Cannabis12Locked
Carvacrol12Locked
DMSO (Dimethyl sulphoxide)12Locked
Delta-tetrahydrocannabinol (THC)12Locked
Honey12Locked
Luteolin12Locked
Melatonin12Locked
Naringenin 12Locked
Pea12Locked
Piperine12Locked
Selenium12Locked
Sulforaphane22Locked
Thymol12Locked
Vitamin A12Locked
Vitamin E12Locked
Zataria multiflora12Locked
Arginine11Locked
Blueberry11Locked
Cannabinoids 11Locked
Curcumin: Degradiation byproducts11Locked
Gotu Kola11Locked
Graviola 11Locked
Mugwort11Locked
Raspberry11Locked
Strawberry11Locked
Tansy11Locked
Toona sinensis 11Locked
3 Therapeutic Actions Researched for Gene Expression
NameACCKFocus
Exercise12Locked
Exercise: Endurance12Locked
Sound Therapy11Locked
24 Pharmacological Actions Researched for Gene Expression
NameACCKFocus
Antidepressive Agents110Locked
Anti-Inflammatory Agents59Locked
Neuroprotective Agents24Locked
Nrf2 activation34Locked
Antiviral Agents33Locked
Angiogenesis Inhibitors12Locked
Anti-Bacterial Agents12Locked
Antioxidants22Locked
Antiproliferative 22Locked
Cell cycle arrest22Locked
Chemoprotective Agents12Locked
Gastrointestinal Agents12Locked
Gastroprotective12Locked
Heat Shock Protein Inducer12Locked
Hypoglycemic Agents12Locked
Anti-Infective Agents11Locked
Anti-metastatic11Locked
Antimicrobial11Locked
Cytoprotective11Locked
Cytotoxic11Locked
Interleukin-6 Downregulation11Locked
Prophylactic Agents11Locked
Superoxide Dismutase Up-regulation11Locked
Tumor Suppressor Protein p53 Upregulation11Locked

View the Evidence:
104 Abstracts with Gene Expression Research

[+]

DNA methylation of the ZNF575 gene in infant cord blood was associated with maternal antidepressant use in pregnancy in two independent cohorts.Jan 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Epigenetics. 2019 03 29 ;11(1):56. Epub 2019 Mar 29. PMID: 30925934
Article Published Date : Jan 28, 2019
Study Type : Human Study
Additional Links
Diseases : Prenatal Chemical Exposures
Additional Keywords : DNA Methylation, Gene Expression
Problem Substances : Antidepressants
[+]

Identification of unique gene expression profile in children with regressive autism spectrum disorder.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2013 ;8(3):e58058. Epub 2013 Mar 8. PMID: 23520485
Article Published Date : Dec 31, 2012
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders
Additional Keywords : Gene Expression
[+]

Low serum 25(OH)D was associated with higher depressive symptom scores.Jul 03, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Nutr. 2015 Jul 4. Epub 2015 Jul 4. PMID: 26141257
Article Published Date : Jul 03, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Depression, Depressive Disorder, Vitamin D Deficiency
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Gene Expression, Risk Reduction
[+]

Magnetic fields and solar cycles-dependent geomagnetic field fluctuations are capable of altering expression of genes related to function of NF-kappaB.Dec 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2010 03 ;7(3):938-65. Epub 2010 Mar 10. PMID: 20617011
Article Published Date : Dec 31, 2009
Study Type : Human Study
Additional Links
Additional Keywords : Gene Expression, Geomagnetic Activity
Anti Therapeutic Actions : Electromagnetic Field Harms
[+]

Maternal BPA exposure may increase autism spectrum disorder susceptibility by dysregulating genes associated with neurological functions.Feb 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2019 Feb 28 ;9(1):3038. Epub 2019 Feb 28. PMID: 30816183
Article Published Date : Feb 27, 2019
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Bisphenol Toxicity, Prenatal Chemical Exposures
Additional Keywords : Gene Expression, Increased Risk
Problem Substances : Bisphenol A
[+]

Prenatal exposure to particulate matter and placental gene expression.May 24, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Int. 2022 May 25 ;165:107310. Epub 2022 May 25. PMID: 35653832
Article Published Date : May 24, 2022
Study Type : Human Study
Additional Links
Diseases : Air Pollution Linked Toxicity, Prenatal Chemical Exposures
Additional Keywords : Gene Expression
[+]

Serum sKlt, FGF-23, and P levels were significantly higher in MS patients compared to the control group.Aug 31, 2016

Pubmed Data : Ann Neurosci. 2016 Sep ;23(3):155-161. Epub 2016 Aug 9. PMID: 27721584
Article Published Date : Aug 31, 2016
Study Type : Human Study
Additional Links
Diseases : Multiple Sclerosis, Vitamin D Deficiency
Additional Keywords : Gene Expression
[+]

Short-term sleep deprivation leads to decreased systemic redox metabolites and altered epigenetic status.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(7):e0181978. Epub 2017 Jul 24. PMID: 28738082
Article Published Date : Dec 31, 2016
Study Type : Human Study
Additional Links
Diseases : Sleep Disorders
Additional Keywords : Epigenetic Modification, Gene Expression
[+]

Single nucleotide polymorphisms associated with statin myalgia and myositis were observed with increased frequency among patients with statin myalgia.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(8):e0181308. Epub 2017 Aug 3. PMID: 28771594
Article Published Date : Dec 31, 2016
Study Type : Human In Vitro, Human Study
Additional Links
Diseases : Statin-Induced Pathologies
Additional Keywords : Gene Expression
Problem Substances : Statin Drugs
[+]

The clinical evidence to date points to an association between BPA exposure and impaired IVF outcome.Dec 14, 2016

Pubmed Data : Hum Reprod. 2016 Dec 15. Epub 2016 Dec 15. PMID: 27979917
Article Published Date : Dec 14, 2016
Study Type : Human In Vitro, Human Study
Additional Links
Diseases : Bisphenol Toxicity, Infertility: Female
Additional Keywords : Gene Expression, Risk Factors
Problem Substances : Bisphenol A
[+]

Vitamin D-related genes RXRG and GC affect low-density lipoprotein cholesterol levels.Aug 14, 2016

Pubmed Data : J Nutr Biochem. 2016 Aug 15 ;38:12-17. Epub 2016 Aug 15. PMID: 27721113
Article Published Date : Aug 14, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Cholesterol: LDL/HDL ratio
Additional Keywords : Gene Expression
[+]

Bisphenol A and bisphenol S alter the promoter activity of the ABCB1 gene encoding P-glycoprotein in the human placenta.Sep 18, 2018

Pubmed Data : Toxicol Appl Pharmacol. 2018 Sep 19 ;359:47-54. Epub 2018 Sep 19. PMID: 30240697
Article Published Date : Sep 18, 2018
Study Type : Human In Vitro
Additional Links
Diseases : Bisphenol Toxicity
Additional Keywords : Gene Expression
Problem Substances : Bisphenol A , Bisphenol S
[+]

Novel genetic associations between lung cancer and indoor radon exposure.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Cancer Prev. 2017 Dec ;22(4):234-240. Epub 2017 Dec 30. PMID: 29302581
Article Published Date : Nov 30, 2017
Study Type : Human In Vitro
Additional Links
Diseases : Lung Cancer
Additional Keywords : Gene Expression, Risk Factors
Problem Substances : Radon
[+]

The results suggest that overexposure to fluoride (160-320 μM) can induce cytotoxicity and regulate relevant genes expression.Feb 28, 2015

Pubmed Data : Biol Trace Elem Res. 2015 Mar 1. Epub 2015 Mar 1. PMID: 25726004
Article Published Date : Feb 28, 2015
Study Type : Human In Vitro
Additional Links
Diseases : Fluoride Toxicity
Additional Keywords : Dose Response, Gene Expression
Problem Substances : Sodium Fluoride
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This finding was corroborated by clinical observation that PER2 down-regulation was associated with poor prognosis in breast cancer patients. Jul 22, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 2013 Jul 23 ;110(30):12331-6. Epub 2013 Jul 8. PMID: 23836662
Article Published Date : Jul 22, 2013
Study Type : Human In Vitro
Additional Links
Diseases : Breast Cancer, Cancer Metastasis, Circadian Dysregulation, Hypoxia
Additional Keywords : Gene Expression, PER2 Protein, Tumor Suppressor Proteins
[+]

Triclosan and octylphenol may promote breast cancer progression.May 18, 2014

Pubmed Data : Chem Res Toxicol. 2014 May 19 ;27(5):834-42. Epub 2014 Apr 8. PMID: 24684733
Article Published Date : May 18, 2014
Study Type : Human In Vitro
Additional Links
Diseases : Breast Cancer
Additional Keywords : Gene Expression
Problem Substances : Octylphenol , Triclosan
[+]

Whole-genome expression analysis in primary human keratinocyte cell cultures exposed to 60 GHz radiation.Jan 31, 2012

Pubmed Data : Bioelectromagnetics. 2012 Feb ;33(2):147-58. Epub 2011 Aug 3. PMID: 21812010
Article Published Date : Jan 31, 2012
Study Type : Human In Vitro
Additional Links
Diseases : Radiation Induced Illness
Additional Keywords : Gene Expression
Anti Therapeutic Actions : 5G Millimeter Wave Radiation
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Analysis of a child who developed abnormal neuropsychiatric symptoms after administration of oseltamivir.Aug 04, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Neurol. 2015 Aug 5 ;15:130. Epub 2015 Aug 5. PMID: 26242979
Article Published Date : Aug 04, 2015
Study Type : Human: Case Report
Additional Links
Diseases : Psychiatric Disorders
Additional Keywords : Gene Expression, Oseltamivir (trade name Tamiflu), psychiatric disorders
Problem Substances : Oseltamivir (trade name Tamiflu)
Adverse Pharmacological Actions : Neurotoxic
[+]

A honey diet elicited a transcriptional profile distinct from sucrose and HFCS diets in bees. Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2014 ;4:5726. Epub 2014 Jul 17. PMID: 25034029
Article Published Date : Dec 31, 2013
Study Type : Insect Study
Additional Links
Substances : Honey
Additional Keywords : Beekeeping, Gene Expression
Problem Substances : High Fructose Corn Syrup
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Apigenin restored immune function and decreased neuroinflammation in an experimental autoimmune encephalomyelitis model. Jun 03, 2015

Pubmed Data : J Neuroimmune Pharmacol. 2015 Jun 4. Epub 2015 Jun 4. PMID: 26040501
Article Published Date : Jun 03, 2015
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Autoimmune Diseases, Brain Inflammation , Encephalomyelitis, Multiple Sclerosis: Relapsing-Remitting
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Gene Expression
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Ascorbic acid deficiency induced inflammation related gene expression in the livers of deficient animals. Jan 31, 2015

Pubmed Data : Nutrition. 2015 Feb ;31(2):373-9. Epub 2014 Aug 1. PMID: 25592017
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Vitamin C Deficiency
Additional Keywords : Gene Expression
Adverse Pharmacological Actions : Inflammatory
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Aspartame and saccharin led to overexpression of the key oncogene (h-Ras) and the downregulation of the tumor suppressor gene (P27) in all treated rats.May 31, 2015

Pubmed Data : Int J Immunopathol Pharmacol. 2015 Jun ;28(2):247-55. Epub 2015 May 26. PMID: 26015492
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Additional Keywords : Gene Expression, Tumor Suppressor Genes
Problem Substances : Artificial Sweeteners, Aspartame, Saccharin
Adverse Pharmacological Actions : Hepatotoxic
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Bisphenol-A induces expression of HOXC6, an estrogen-regulated homeobox-containing gene associated with breast cancer.May 31, 2015

Pubmed Data : Biochim Biophys Acta. 2015 Jun ;1849(6):697-708. Epub 2015 Feb 25. PMID: 25725483
Article Published Date : May 31, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Bisphenol-A Toxicity, Breast Cancer
Additional Keywords : Gene Expression, Risk Factors
Problem Substances : Bisphenol A
[+]

Boron enhances early embryonic gene expressions and improves fetal development of rats.Nov 30, 2018

Pubmed Data : J Trace Elem Med Biol. 2018 Dec ;50:34-46. Epub 2018 Jun 2. PMID: 30262302
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Boron
Additional Keywords : Gene Expression
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Chronic exposure to environmentally relevant concentrations of bisphenol S differentially affects cognitive behaviors in adult female zebrafish.Jan 24, 2020

Pubmed Data : Environ Pollut. 2020 Jan 25 ;261:114060. Epub 2020 Jan 25. PMID: 32045791
Article Published Date : Jan 24, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity
Additional Keywords : Gene Expression
Problem Substances : Bisphenol S
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Chronic exposure to maternally delivered BPA significantly alters the transcript expression profiles of several coding and non-coding genes in rhesus monkey fetal heart tissue.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(2):e89096. Epub 2014 Feb 25. PMID: 24586524
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Cardiovascular Diseases, Fetal Origin of Adult Disease
Additional Keywords : Gene Expression, Risk Factors
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Cardiotoxic
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Curcumin and resveratrol may be useful potential agents in combating DEHP-induced testicular dysfunction.Sep 07, 2015

Pubmed Data : Gen Comp Endocrinol. 2015 Sep 8. Epub 2015 Sep 8. PMID: 26361869
Article Published Date : Sep 07, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin, Resveratrol
Diseases : Phthalate Toxicity
Pharmacological Actions : Chemoprotective Agents, Heat Shock Protein Inducer, Nrf2 activation
Additional Keywords : Gene Expression
Problem Substances : Phthalates
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Curcumin treatment enhances the effect of exercise on mitochondrial biogenesis in skeletal muscles.Sep 30, 2015

Pubmed Data : Metabolism. 2015 Oct ;64(10):1334-47. Epub 2015 Jul 21. PMID: 26278015
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin, DMSO (Dimethyl sulphoxide)
Therapeutic Actions : Exercise: Endurance
Additional Keywords : Gene Expression, Mitochondrial Biogenesis
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Developmental exposure to lead induces transgenerational changes to zebrafish brain transcriptome.Dec 01, 2019

Pubmed Data : Chemosphere. 2019 Dec 2 ;244:125527. Epub 2019 Dec 2. PMID: 31816550
Article Published Date : Dec 01, 2019
Study Type : Animal Study
Additional Links
Diseases : Prenatal Chemical Exposures
Additional Keywords : Gene Expression, Transgenerational inheritance
Problem Substances : Lead
Adverse Pharmacological Actions : Neurotoxic
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Effects of Bisphenol A on Foxl2 gene expression and DNA damage in adult viviparous fish Goodea atripinnis.Jan 31, 2020

Pubmed Data : J Toxicol Environ Health A. 2020 Feb 1 ;83(3):95-112. Epub 2020 Feb 20. PMID: 32075523
Article Published Date : Jan 31, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, DNA damage
Additional Keywords : Gene Expression
Problem Substances : Bisphenol A
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Embryonic exposure to low concentration of BPA/BPS can impair the normal expressions of pancreatic-associated genes and DNA methylation pattern.Jan 31, 2021

Pubmed Data : Arch Environ Contam Toxicol. 2021 Feb ;80(2):450-460. Epub 2021 Jan 20. PMID: 33471154
Article Published Date : Jan 31, 2021
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Metabolic Diseases, Prenatal Chemical Exposures
Additional Keywords : Gene Expression, Risk Factors
Problem Substances : Bisphenol A
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Exposure to electronic cigarette vapors affects pulmonary and systemic expression of circadian molecular clock genes.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Physiol Rep. 2017 Oct ;5(19). Epub 2017 Oct 16. PMID: 29038357
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Additional Keywords : Gene Expression
Problem Substances : Electronic Cigarettes, Propylene Glycol
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Fruit flies given a high sugar diet were found to have shorter lifespans. Jan 09, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Rep. 2017 Jan 10 ;18(2):299-306. PMID: 28076775
Article Published Date : Jan 09, 2017
Study Type : Insect Study
Additional Links
Diseases : High Sugar Diet
Additional Keywords : Gene Expression
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Gene expression changes in the skin of rats induced by prolonged 35 GHz millimeter-wave exposure.Feb 29, 2008

Pubmed Data : Radiat Res. 2008 Mar ;169(3):288-300. PMID: 18302488
Article Published Date : Feb 29, 2008
Study Type : Animal Study
Additional Links
Diseases : Radiation Induced Illness
Additional Keywords : Gene Expression
Anti Therapeutic Actions : 5G Millimeter Wave Radiation
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Glyphosate and the Roundup formulation is developmentally toxic to the forebrain and midbrain in zebrafish. Jan 03, 2016

Pubmed Data : Environ Toxicol Pharmacol. 2016 Jan 4 ;42:45-54. Epub 2016 Jan 4. PMID: 26773362
Article Published Date : Jan 03, 2016
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity
Additional Keywords : Gene Expression
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Neurotoxic
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High-fructose diets could induce aberrant expression of hepatic microRNA.Feb 19, 2017

Pubmed Data : J Nutr Biochem. 2017 Feb 20 ;43:125-131. Epub 2017 Feb 20. PMID: 28284064
Article Published Date : Feb 19, 2017
Study Type : Animal Study
Additional Links
Diseases : High Fructose Diet
Additional Keywords : Gene Expression, Risk Factors
Problem Substances : High Fructose Corn Syrup
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In utero exposure of BPA resulted in significant changes to inflammatory modulators within mammary tissue.Feb 23, 2016

Pubmed Data : Horm Cancer. 2016 Feb 24. Epub 2016 Feb 24. PMID: 26911702
Article Published Date : Feb 23, 2016
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Breast Cancer, Prenatal Chemical Exposures
Additional Keywords : Gene Expression, Risk Factors
Problem Substances : Bisphenol A
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Luteolin may inhibit tumor angiogenesis and tumor cell proliferation by down-regulation of LFA- 3 and PCNA in H22 hepatoma cells. Dec 31, 2014

Pubmed Data : Genet Mol Res. 2015 ;14(4):14448-56. Epub 2015 Nov 19. PMID: 26600503
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Luteolin
Diseases : Liver Cancer
Pharmacological Actions : Angiogenesis Inhibitors
Additional Keywords : Gene Expression
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Male offspring from BPA-treated mothers presented symptoms of diabesity.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(6):e100214. Epub 2014 Jun 24. PMID: 24959901
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Bisphenol-A Toxicity
Additional Keywords : Gene Expression, Transgenerational Epigenetic Modification
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Diabetogenic
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Maternal glyphosate-based herbicide exposure alters antioxidant-related genes in the brain and serum metabolites of male rat offspring.Jun 17, 2019

Pubmed Data : Neurotoxicology. 2019 Jun 18 ;74:121-131. Epub 2019 Jun 18. PMID: 31226268
Article Published Date : Jun 17, 2019
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity, Prenatal Chemical Exposures
Additional Keywords : Gene Expression
Problem Substances : Glyphosate
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Maternal vitamin B12 deficiency in rats alters DNA methylation in metabolically important genes in their offspring.Apr 30, 2020

Pubmed Data : Mol Cell Biochem. 2020 May ;468(1-2):83-96. Epub 2020 Mar 18. PMID: 32189172
Article Published Date : Apr 30, 2020
Study Type : Animal Study
Additional Links
Diseases : Vitamin B 12 Deficiency
Additional Keywords : DNA Methylation, Gene Expression, Transgenerational inheritance
[+]

Naringenin attenuates hepatitis B virus X protein-induced hepatic steatosisNov 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Nov 28 ;17(1):505. Epub 2017 Nov 28. PMID: 29183361
Article Published Date : Nov 27, 2017
Study Type : Transgenic Animal Study
Additional Links
Substances : Naringenin
Diseases : Hepatic Steatosis, Hepatitis B
Additional Keywords : Gene Expression
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pea seed coats fractions can improve glycemia and may have a protective role against HFD-induced alterations in gut microbiota and mucus layer.Nov 11, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Nov 12 ;9(11). Epub 2017 Nov 12. PMID: 29137145
Article Published Date : Nov 11, 2017
Study Type : Animal Study
Additional Links
Substances : Pea
Diseases : Glycemia, High Fat Diet
Pharmacological Actions : Gastrointestinal Agents, Hypoglycemic Agents
Additional Keywords : Gene Expression
[+]

Perinatal bisphenol A exposure and reprogramming of imprinted gene expression in the adult mouse brain.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Genet. 2019 ;10:951. Epub 2019 Oct 10. PMID: 31649729
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Prenatal Chemical Exposures
Additional Keywords : Gene Expression
Problem Substances : Bisphenol A
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Perinatal fluoxetine exposure results in social deficits and reduced monoamine oxidase gene expression in mice.Jun 02, 2019

Pubmed Data : Brain Res. 2019 Jun 3. Epub 2019 Jun 3. PMID: 31170382
Article Published Date : Jun 02, 2019
Study Type : Animal Study
Additional Links
Diseases : Autism Spectrum Disorders, Prenatal Chemical Exposures
Additional Keywords : Gene Expression, Risk Factors
Problem Substances : Fluoxetine (trade name Prozac)
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Piperine may contribute to prevention or reduction of colonic inflammation.Jun 30, 2015

Pubmed Data : J Ethnopharmacol. 2015 Jul 1 ;169:109-23. Epub 2015 Apr 21. PMID: 25907981
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Substances : Piperine
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective
Additional Keywords : Gene Expression, Risk Reduction
[+]

Pro-inflammatory cytokine IL-1β suppresses melatonin secretion and its action seems to be targeted on the reduction of pineal AA-NAT protein expression.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:526464. Epub 2015 Aug 3. PMID: 26339621
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Melatonin
Additional Keywords : Gene Expression
[+]

Pubertal BPA exposure altered MaSC gene expression and function such that they induced early neoplastic transformation.Mar 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Prev Res (Phila). 2014 Apr ;7(4):445-55. Epub 2014 Feb 11. PMID: 24520039
Article Published Date : Mar 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Breast Cancer
Additional Keywords : Gene Expression
Problem Substances : Bisphenol A
[+]

Resveratrol restores the antinociceptive effect of morphine by reversing morphine infusion induced spinal cord neuroinflammation and increase in TNFR1 expression.Jun 11, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Formos Med Assoc. 2015 Jun 12. Epub 2015 Jun 12. PMID: 26078221
Article Published Date : Jun 11, 2015
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Brain Inflammation , Morphine Tolerance/Dependence, Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents
Additional Keywords : Disease Reversal, Gene Expression
[+]

Selenium deficiency causes immune damage.Jul 02, 2020

Pubmed Data : Food Funct. 2020 Jul 3. Epub 2020 Jul 3. PMID: 32618989
Article Published Date : Jul 02, 2020
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Mineral Deficiencies: Selenium
Additional Keywords : Gene Expression
Adverse Pharmacological Actions : Immunotoxic
[+]

Several genes associated with bone metabolism and genes in the Hedgehog and Notch signalling pathways were downregulated significantly by nicotine.May 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2018 Jun ;17(6):8269-8281. Epub 2018 Apr 13. PMID: 29658611
Article Published Date : May 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Nicotine/Tobacco Toxicity
Additional Keywords : Gene Expression
[+]

Simvastatin altered gene targets known to be implicated in proteasomal and lysosomal mediated muscle proteolysis, carbohydrate oxidation, oxidative stress and inflammation.Jan 14, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Physiol. 2009 Jan 15 ;587(Pt 1):219-30. Epub 2008 Nov 10. PMID: 19001041
Article Published Date : Jan 14, 2009
Study Type : Animal Study
Additional Links
Diseases : Myopathy, Statin-Induced Pathologies
Additional Keywords : Gene Expression
Problem Substances : Simvastatin, Statin Drugs
Adverse Pharmacological Actions : Inflammatory, Interleukin-6 up-regulation, Tumor necrosis factorα (TNFα) up-regulation
[+]

Sodium fluoride epigenetically impaired mouse oocyte maturation and embryonic development.Sep 01, 2014

Pubmed Data : Environ Sci Technol. 2014 Sep 2 ;48(17):10398-405. Epub 2014 Aug 14. PMID: 25102367
Article Published Date : Sep 01, 2014
Study Type : Animal Study
Additional Links
Diseases : Infertility
Additional Keywords : Dose Response, Embryonic Development, Gene Expression, Prenatal Epigenetic Programming
Problem Substances : Sodium Fluoride
Adverse Pharmacological Actions : Anti-Fertility
[+]

Statin therapy drives a profound remodelling of the gut microbiota, hepatic gene deregulation and metabolic alterations in mice.Aug 08, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microbiome. 2017 Aug 9 ;5(1):95. Epub 2017 Aug 9. PMID: 28793934
Article Published Date : Aug 08, 2017
Study Type : Animal Study
Additional Links
Diseases : Dysbiosis, Statin-Induced Pathologies
Additional Keywords : Gene Expression, Risk Factors
Problem Substances : Statin Drugs
[+]

Sublethal doses of imidacloprid affect mrjp expression and likely weaken bee colonies.Jul 17, 2017

Pubmed Data : Insect Biochem Mol Biol. 2017 Jul 18 ;88:12-20. Epub 2017 Jul 18. PMID: 28732753
Article Published Date : Jul 17, 2017
Study Type : Insect Study
Additional Links
Diseases : Bee Colony Collapse
Additional Keywords : Bee Colony Collapse, Gene Expression, Honeybee, pesticides
Problem Substances : Pesticides
[+]

The administration of high concentrations of fluoride to female mice results in ovarian damage and significantly reduces the number and the fertilization potential of mature oocytes.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(6):e0129594. Epub 2015 Jun 8. PMID: 26053026
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Female Reproductive Development Abnormalities, Infertility: Female
Additional Keywords : Gene Expression
Problem Substances : Fluoride, Sodium Fluoride
Adverse Pharmacological Actions : Anti-Fertility
[+]

The combination of THC and CBD exhibits a better therapeutic profile than each cannabis component alone against Alzheimer's disease.Dec 31, 2014

Pubmed Data : J Alzheimers Dis. 2015 ;43(3):977-91. PMID: 25125475
Article Published Date : Dec 31, 2014
Study Type : Transgenic Animal Study
Additional Links
Substances : Cannabidiol, Cannabis, Delta-tetrahydrocannabinol (THC)
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Gene Expression, Natural Substance Synergy
[+]

The pesticide dieldrin disrupts proteins related to oxidative respiration and mitochondrial stress in the central nervous system of zebrafish.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Data Brief. 2017 Apr ;11:628-633. Epub 2017 Mar 11. PMID: 28367483
Article Published Date : Mar 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Pesticide Toxicity
Additional Keywords : Gene Expression
Problem Substances : Pesticides
[+]

The upregulation of ribosome-associated genes and the impairment of testis-specific gene expression are significantly enhanced upon BPA exposure with a high-sugar diet. Apr 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genetics. 2014 May ;197(1):147-57. Epub 2014 Mar 10. PMID: 24614930
Article Published Date : Apr 30, 2014
Study Type : Insect Study
Additional Links
Diseases : Bisphenol-A Toxicity
Additional Keywords : Gene Expression, Synergistic Toxicity
Problem Substances : Bisphenol A , Sugar Sweetened Beverages
[+]

The Zataria multiflora extract had a potent bactericidal effect against A. baumannii that could downregulate the ompA gene.Jul 23, 2019

Pubmed Data : J Cell Biochem. 2019 Jul 24. Epub 2019 Jul 24. PMID: 31338900
Article Published Date : Jul 23, 2019
Study Type : Animal Study
Additional Links
Substances : Carvacrol, Thymol, Zataria multiflora
Diseases : Acinetobacter baumannii infection
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Gene Expression
[+]

These findings may aid in understanding the mechanisms of the association between BPA exposure and cardiovascular disorders.Sep 12, 2016

Pubmed Data : Ups J Med Sci. 2016 Sep 13:1-8. Epub 2016 Sep 13. PMID: 27622962
Article Published Date : Sep 12, 2016
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Fructose-Induced Toxicity
Additional Keywords : Gene Expression
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Cardiotoxic
[+]

These results reveal the tissue-specific nature of gene expression responses to chronic alcohol exposure and the ClockΔ19 mutation. Sep 01, 2015

Pubmed Data : Alcohol Clin Exp Res. 2015 Sep 2. Epub 2015 Sep 2. PMID: 26332085
Article Published Date : Sep 01, 2015
Study Type : Animal Study
Additional Links
Diseases : Alcohol Toxicity , Alcoholism, Circadian Dysregulation, Inflammation
Additional Keywords : Circadian Clock Proteins, Gene Expression
[+]

These results suggest that chronic exposure to glyphosate based herbicides at an ultra-low environmental dose can result in liver and kidney damage.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health. 2015 ;14(1):70. Epub 2015 Aug 25. PMID: 26302742
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Glyphosate Toxicity
Additional Keywords : Gene Expression
Problem Substances : Glyphosate
Adverse Pharmacological Actions : Hepatotoxic, Renotoxic
[+]

These results suggest that prenatal bisphenol S exposure potentially increases the susceptibility to high fat diet-induced adipogenesis.Apr 18, 2020

Pubmed Data : Sci Total Environ. 2020 Apr 19 ;728:138759. Epub 2020 Apr 19. PMID: 32403013
Article Published Date : Apr 18, 2020
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity, Obesity, Prenatal Chemical Exposures
Additional Keywords : Gene Expression, Increased Risk
Problem Substances : Bisphenol P
[+]

This data provides a molecular basis for observed adverse effects of insecticides to bees.Apr 08, 2017

Pubmed Data : Environ Pollut. 2017 Apr 9 ;226:48-59. Epub 2017 Apr 9. PMID: 28402838
Article Published Date : Apr 08, 2017
Study Type : Insect Study
Additional Links
Diseases : Pesticide Toxicity
Additional Keywords : Gene Expression, Honeybee
Problem Substances : Chlorpyrifos, Organophosphate Pesticides, Pesticides
[+]

This study demonstrates that alternatives to BPA used in the manufacture of BPA-free products are not necessarily safer.Dec 09, 2015

Pubmed Data : Endocrinology. 2015 Dec 10:en20151785. Epub 2015 Dec 10. PMID: 26653335
Article Published Date : Dec 09, 2015
Study Type : Animal Study
Additional Links
Diseases : Bisphenol Toxicity
Additional Keywords : Gene Expression
Problem Substances : Bisphenol A , Bisphenol S
[+]

This study suggests that BPA exposure may increase susceptibility to atherosclerosis in the setting of hyperlipidemia.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(10):e110977. Epub 2014 Oct 21. PMID: 25333893
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Atherosclerosis
Additional Keywords : Gene Expression, Increased Risk
Problem Substances : Bisphenol A
Adverse Pharmacological Actions : Atherogenic, Inflammatory
[+]

Triclosan could induce changes in the fetal hypothalamic transcriptomics mainly connected to food intake pathways and metabolism.May 03, 2016

Pubmed Data : Endocrinology. 2016 May 4:en20161080. Epub 2016 May 4. PMID: 27145008
Article Published Date : May 03, 2016
Study Type : Animal Study
Additional Links
Diseases : Fetal Origin of Adult Disease
Additional Keywords : Gene Expression
Problem Substances : Triclosan
[+]

Vitamin A deficiency may retard fetal lung development or influence the differentiation of critical cell lines.Nov 30, 1998

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Physiol Lung Cell Mol Physiol. 1998 Dec 1 ;275(6):L1184-L1191. PMID: 29586289
Article Published Date : Nov 30, 1998
Study Type : Animal Study
Additional Links
Substances : Vitamin A
Diseases : Fetal Origin of Adult Disease, Vitamin A Deficiency
Additional Keywords : Gene Expression
[+]

Vitamin E deficiency disrupts gene expression networks during zebrafish development.Jan 29, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Jan 30 ;13(2). Epub 2021 Jan 30. PMID: 33573233
Article Published Date : Jan 29, 2021
Study Type : Animal Study
Additional Links
Substances : Vitamin E
Diseases : Vitamin E Deficiency
Additional Keywords : Gene Expression
[+]

Voluntary exercise blocked the increase in expression of pro-inflammatory genes induced by a western diet in mice. Jul 31, 2016

Pubmed Data : Brain Behav Immun. 2016 Aug 1. Epub 2016 Aug 1. PMID: 27492632
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Therapeutic Actions : Exercise
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Gene Expression
Anti Therapeutic Actions : Western Diet
Adverse Pharmacological Actions : Inflammatory
[+]

This review organizes the current knowledge in the context of cannabinoids pharmacogenetics.May 21, 2017

Pubmed Data : Eur J Drug Metab Pharmacokinet. 2017 May 22. Epub 2017 May 22. PMID: 28534260
Article Published Date : May 21, 2017
Study Type : Review
Additional Links
Substances : Cannabinoids
Additional Keywords : Gene Expression
[+]

A spiroketal-enol ether derivative from Tanacetum vulgare selectively inhibits HSV-1 and HSV-2 glycoprotein accumulation in Vero cells.Jun 30, 2015

Pubmed Data : Antiviral Res. 2015 Jul ;119:8-18. Epub 2015 Apr 13. PMID: 25882624
Article Published Date : Jun 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Tansy
Diseases : Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2
Pharmacological Actions : Anti-Infective Agents, Antiviral Agents
Additional Keywords : Gene Expression, Plant Extracts
[+]

Aluminium has been demonstrated to impact the CNS at every level, including by changing gene expression.Dec 31, 2013

Pubmed Data : Immunotherapy. 2014 ;6(10):1055-71. PMID: 25428645
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Autoimmune Diseases, Neurodegenerative Diseases
Additional Keywords : aluminum, aluminum toxicity, Autoimmune Diseases, Gene Expression, Neurodegenerative diseases, Vaccine Adjuvants
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

aluminum may induce apoptosis in astrocytes via ER stress by impairing the protein-folding machinery.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Prev Med. 2011 Jan ;16(1):16-24. Epub 2010 Jun 22. PMID: 21432213
Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity
Additional Keywords : Gene Expression
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Aqueous extracts from Toona sinensis roem may be used as an alternative treatment and prophylaxis against influenza A virus. Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2013 ;2013:479718. Epub 2013 Sep 2. PMID: 24073006
Article Published Date : Dec 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Toona sinensis
Diseases : H1N1 Infection, Influenza A
Pharmacological Actions : Antiviral Agents, Prophylactic Agents
Additional Keywords : Gene Expression, Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

Arginine could help protect yeast cells from ethanol damage.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 ;6:31311. Epub 2016 Aug 10. PMID: 27507154
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Arginine
Diseases : Alcohol Toxicity
Pharmacological Actions : Cytoprotective
Additional Keywords : Gene Expression
Problem Substances : Ethanol
[+]

Autism genes are selectively targeted by environmental pollutants.Oct 26, 2016

Pubmed Data : Neurochem Int. 2016 Oct 27. Epub 2016 Oct 27. PMID: 27984170
Article Published Date : Oct 26, 2016
Study Type : Review
Additional Links
Diseases : Autism
Additional Keywords : Gene Expression
Problem Substances : Acetaminophen, Benzo(a)pyrene, Bisphenol A , Heavy Metals, Pesticides, Phthalates
[+]

Because aberrant epigenetic modifications are an important hallmark of cancer cells, carcinogenic effects of circadian disruption may have an epigenetic basis.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Chin J Cancer. 2015 ;34:38. Epub 2015 Aug 8. PMID: 26253128
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Diseases : Cancers: All, Circadian Dysregulation
Additional Keywords : Epigenetic Modification In Cancer, Gene Expression
[+]

Bisphenol a affects endometrial stromal cells decidualization, involvement of epigenetic regulation.Feb 18, 2020

Pubmed Data : J Steroid Biochem Mol Biol. 2020 Feb 19 ;200:105640. Epub 2020 Feb 19. PMID: 32087250
Article Published Date : Feb 18, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity
Additional Keywords : Epigenetic Modification, Gene Expression
Problem Substances : Bisphenol A
[+]

Bisphenol A alters transcript levels of biomarker genes for Major Depressive Disorder in vascular endothelial cells and colon cancer cells.May 31, 2016

Pubmed Data : Chemosphere. 2016 Jun ;153:75-7. Epub 2016 Mar 21. PMID: 27010169
Article Published Date : May 31, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Depression, Psychiatric Disorders
Additional Keywords : Gene Expression
Problem Substances : Bisphenol A
[+]

Bisphenol A and S impaired ovine granulosa cell steroidogenesis.Jan 31, 2020

Pubmed Data : Reproduction. 2020 Feb 1. Epub 2020 Feb 1. PMID: 32092037
Article Published Date : Jan 31, 2020
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity
Additional Keywords : Gene Expression
Problem Substances : Bisphenol A , Bisphenol S
[+]

Both BPA and BPS could be involved in obesity and steatosis processes, but through two different metabolic pathways.Oct 14, 2014

Pubmed Data : Toxicol Appl Pharmacol. 2014 Oct 15 ;280(2):224-35. Epub 2014 Aug 8. PMID: 25111128
Article Published Date : Oct 14, 2014
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol-A Toxicity, Bisphenol S Toxicity, Hepatic Steatosis, Obesity
Additional Keywords : Gene Expression, Risk Factors
Problem Substances : Bisphenol A , Bisphenol S
[+]

Both epidemiological and experimental evidences demonstrate that BPA affects reproduction-related gene expression and epigenetic modification that are closely associated with infertility.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2015 ;12(9):11101-16. Epub 2015 Sep 7. PMID: 26371021
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Diseases : Infertility: Female
Additional Keywords : Epigenetic Modification, Gene Expression
Problem Substances : Bisphenol A
[+]

Curcumin alters gene expression-associated DNA damage, cell cycle, cell survival and cell migration and invasion in NCI-H460 human lung cancer cells in vitro.Sep 30, 2015

Pubmed Data : Oncol Rep. 2015 Oct ;34(4):1853-74. Epub 2015 Jul 29. PMID: 26238775
Article Published Date : Sep 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Carcinoma: Non-Small-Cell Lung, Lung Cancer
Pharmacological Actions : Anti-metastatic, Cell cycle arrest, Cytotoxic
Additional Keywords : Gene Expression, Gene Expression Regulation
[+]

Current data suggest that curcumin undergoes degradation due to roasting and its degradation product exhibit significant biological activity in cultured cells.Mar 10, 2015

Pubmed Data : Food Funct. 2015 Mar 11 ;6(3):887-93. PMID: 25619943
Article Published Date : Mar 10, 2015
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Curcumin: Degradiation byproducts
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation
Additional Keywords : Gene Expression
[+]

Effect of sulforaphane and 5-Aza-2'-deoxycytidine on melanoma cell growth.Jun 26, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Medicines (Basel). 2019 Jun 27 ;6(3). Epub 2019 Jun 27. PMID: 31252639
Article Published Date : Jun 26, 2019
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : Melanoma
Pharmacological Actions : Antiproliferative
Additional Keywords : Gene Expression
[+]

Genome-wide analysis of low dose bisphenol-A (BPA) exposure in human prostate cells.Apr 30, 2019

Pubmed Data : Curr Genomics. 2019 May ;20(4):260-274. PMID: 32030086
Article Published Date : Apr 30, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity
Additional Keywords : Gene Expression
Problem Substances : Bisphenol A
[+]

Graviola leaf extracts reduced the generation of reactive oxygen species (ROS) induced by H2O2 in a dose-dependent manner. Feb 16, 2016

Pubmed Data : Food Funct. 2016 Feb 17 ;7(2):861-71. PMID: 26674326
Article Published Date : Feb 16, 2016
Study Type : In Vitro Study
Additional Links
Substances : Graviola
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Nrf2 activation, Superoxide Dismutase Up-regulation
Additional Keywords : Dose Response, Gene Expression
[+]

In-vitro study of the effect of Centella asiatica on cholera toxin production and the gene expression level of ctxA gene in Vibrio cholerae isolates.Feb 13, 2021

Pubmed Data : J Ethnopharmacol. 2021 Feb 14:113930. Epub 2021 Feb 14. PMID: 33596471
Article Published Date : Feb 13, 2021
Study Type : In Vitro Study
Additional Links
Substances : Gotu Kola
Diseases : Cholera
Additional Keywords : Gene Expression
[+]

Physiologically relevant amounts of iron and aluminum are capable of inducing Fenton chemistry-triggered gene expression.Oct 31, 2005

Pubmed Data : J Alzheimers Dis. 2005 Nov ;8(2):117-27; discussion 209-15. PMID: 16308480
Article Published Date : Oct 31, 2005
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Alzheimer's Disease, Inflammation
Additional Keywords : Gene Expression
Problem Substances : Aluminum
[+]

Recent research revealed that topoisomerases induced expression of the same group of genes as those associated with autism. Aug 10, 2015

Pubmed Data : Int J Dev Neurosci. 2015 Aug 11. Epub 2015 Aug 11. PMID: 26456455
Article Published Date : Aug 10, 2015
Study Type : Review
Additional Links
Diseases : Autism
Additional Keywords : Gene Expression
[+]

Sub-lethal glyphosate exposure alters flowering phenology and causes transient male-sterility in Brassica spp.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Plant Biol. 2014 ;14:70. Epub 2014 Mar 21. PMID: 24655547
Article Published Date : Dec 31, 2013
Study Type : Plant Study
Additional Links
Additional Keywords : Gene Expression
Problem Substances : Glyphosate
[+]

Supplementation of vitamin D may improve wound healing and regeneration in patients with a vitamin D deficiency.May 20, 2016

Pubmed Data : Burns. 2016 May 21. Epub 2016 May 21. PMID: 27222384
Article Published Date : May 20, 2016
Study Type : In Vitro Study
Additional Links
Substances : Vitamin D
Diseases : Vitamin D Deficiency, Wound Healing
Additional Keywords : Gene Expression
[+]

The genetic basis of high-carbohydrate and high-monosodium glutamate diet related to the increase of likelihood of type 2 diabetes mellitus.Mar 13, 2020

Pubmed Data : Endocrine. 2020 Mar 14. Epub 2020 Mar 14. PMID: 32172486
Article Published Date : Mar 13, 2020
Study Type : Review
Additional Links
Diseases : Diabetes Mellitus: Type 2
Additional Keywords : Gene Expression, Increased Risk
Problem Substances : Monosodium Glutamate (MSG)
[+]

The results of the present study suggested that drug exposure may alter the aggressiveness and metastatic potential of cancer cells.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2015 Sep ;12(3):3236-42. Epub 2015 May 25. PMID: 26004767
Article Published Date : Aug 31, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Cancers: All, Lung Cancer
Additional Keywords : Gene Expression
Anti Therapeutic Actions : Chemotherapy
[+]

These findings reveal a cell-level systematic response to audible sound and uncover novel relationships between life and sound.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2018 ;13(1):e0188764. Epub 2018 Jan 31. PMID: 29385174
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Therapeutic Actions : Sound Therapy
Additional Keywords : Gene Expression
[+]

These findings stress the need for careful toxicological characterization of BPA analogs in the future.Jul 31, 2015

Pubmed Data : Toxicol In Vitro. 2015 Aug ;29(5):1060-9. Epub 2015 Apr 22. PMID: 25912373
Article Published Date : Jul 31, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity
Additional Keywords : Gene Expression
Problem Substances : Bisphenol A , Bisphenol S
[+]

These results suggest that the three berry extracts exert potent antimicrobial effects and inhibit the expression of the virulence factors of V. choleraeAug 20, 2015

Pubmed Data : Phytother Res. 2015 Aug 21. Epub 2015 Aug 21. PMID: 26292998
Article Published Date : Aug 20, 2015
Study Type : In Vitro Study
Additional Links
Substances : Blueberry, Raspberry, Strawberry
Diseases : Cholera, Gram-Negative Bacterial Infections, Gram-Positive Bacterial Infections, Listeria Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Gene Expression, Plant Extracts
[+]

This review has proposed that epigenetic mechanisms are causing persistent changes in gene expression of estrogen receptor beta that contribute to ASD risk in offspring.Nov 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Hypotheses. 2015 Dec ;85(6):1006-11. Epub 2015 Sep 6. PMID: 26364046
Article Published Date : Nov 30, 2015
Study Type : Review
Additional Links
Diseases : Autism Spectrum Disorders
Additional Keywords : Gene Expression, Risk Factors, Transgenerational Epigenetic Modification
Problem Substances : Oral Contraceptives
[+]

This scoping review recapitulates the possible effects of BPA that may lead to obesity with the evidence of current in vivo trials.Mar 08, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2022 Mar 9 ;23(6). Epub 2022 Mar 9. PMID: 35328389
Article Published Date : Mar 08, 2022
Study Type : Review
Additional Links
Diseases : Bisphenol Toxicity, Obesity
Additional Keywords : Gene Expression
Problem Substances : Bisphenol A
[+]

This shows for the first time that Nrf2 action can potently block HIV infection.Mar 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS Pathog. 2016 Apr ;12(4):e1005581. Epub 2016 Apr 19. PMID: 27093399
Article Published Date : Mar 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Sulforaphane
Diseases : HIV Infections
Pharmacological Actions : Antioxidants, Antiviral Agents, Nrf2 activation
Additional Keywords : Epigenetic Modification, Gene Expression
[+]

Transcriptome analysis reveals the anti-tumor mechanism of eucalyptol treatment on neuroblastoma cell line SH-SY5Y.Nov 03, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurochem Res. 2022 Nov 4. Epub 2022 Nov 4. PMID: 36331666
Article Published Date : Nov 03, 2022
Study Type : In Vitro Study
Additional Links
Substances : Mugwort
Diseases : Neuroblastoma
Pharmacological Actions : Antiproliferative , Cell cycle arrest, Tumor Suppressor Protein p53 Upregulation
Additional Keywords : Gene Expression
[+]

Transcriptome analysis reveals the contribution of thermal and the specific effects in cellular response to millimeter wave exposure.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2014 ;9(10):e109435. Epub 2014 Oct 10. PMID: 25302706
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Additional Keywords : Gene Expression
Anti Therapeutic Actions : 5G Millimeter Wave Radiation

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