Gene Expression Regulation

Name	AC	CK
Bisphenol A	2	6
Doxorubicin	1	5
Acetaminophen	2	4
Aflatoxin	2	4
Aluminum	2	3
Calcium Carbonate	1	2
Formaldehyde	1	2
Insulin	1	2
Mercury	1	2
Paracetamol	1	2
Pesticides	1	2
Meat: Cooked	1	1
Paraquat	1	1
Polycyclic aromatic hydrocarbon	1	1

Name	AC	CK
Inflammation	27	91
Obesity	47	90
Oxidative Stress	29	66
High Fat Diet	31	61
Breast Cancer	31	52
Lung Cancer	20	43
Diabetes Mellitus: Type 2	14	41
Polycystic Ovary Syndrome	4	40
Colon Cancer	17	29
Prostate Cancer	17	29
Aging	10	26
Vitamin D Deficiency	6	26
Colorectal Cancer	15	23
Alzheimer's Disease	14	22
Gestational Diabetes	3	22
DNA damage	6	21
Hyperlipidemia	7	21
Nonalcoholic fatty liver disease (NAFLD)	12	21
Insulin Resistance	11	20
Wound Healing	5	19
Cancers: All	12	18
Carcinoma: Non-Small-Cell Lung	6	18
Oral Cancer	7	18
Cancers: Drug Resistant	8	17
Hypercholesterolemia	8	16
Atherosclerosis	8	15
Liver Cancer	12	15
Osteoarthritis	4	15
Hepatic Steatosis	7	13
Rheumatoid Arthritis	3	13
Asthma	3	12
Breast Cancer: Triple Negative	12	12
Diabetes Mellitus: Type 2: Prevention	2	12
Hypertension	2	12
Systemic Lupus Erythematosus	2	12
Diabetic Complications	6	11
Ulcerative Colitis	2	11
Acne	1	10
Anemia: Sickle Cell	1	10
Back Pain	1	10
Breast Cancer: BRCA1	1	10
Breast Cancer: Drug Resistant	2	10
C-Reactive Protein	1	10
Carcinoma: Small Cell Lung	1	10
Coronary Artery Disease	1	10
Diabetes: Gestational	1	10
Endothelial Dysfunction	1	10
Fibrosarcoma	1	10
Glaucoma	1	10
Glioblastoma Multiforme	1	10
Irritable Bowel Syndrome	1	10
Leukemia: Monocytic	1	10
Lung Cancer: Metastatic	1	10
Metabolic Diseases	5	10
Metabolic Syndrome X	6	10
Miscarriage: Recurrent	1	10
Multiple Sclerosis	5	10
Schizophrenia	1	10
Sitting Sickness	1	10
Cognitive Decline/Dysfunction	5	9
Lipid Peroxidation	5	9
Cervical Cancer	8	8
Diabetes Mellitus: Type 1	4	7
Gastric Cancer	6	7
Glioblastoma	3	7
Alcoholic Liver Disease	3	6
Bisphenol Toxicity	2	6
Bladder Cancer	5	6
Cancer Metastasis	3	6
Chemically-Induced Liver Damage	3	6
Diabetic Nephropathy	3	6
Memory Loss	3	6
Pancreatic Cancer	5	6
Astrocytoma	1	5
Breast Cancer: Metastatic	3	5
Chronic Obstructive Pulmonary Disease	1	5
Colon Cancer: Prevention	3	5
Dyslipidemias	3	5
Graves Disease	1	5
Hydrogen Peroxide Induced Toxicity	1	5
Leukemia: Chronic myelogenous leukemia (CML)	1	5
Liver Cirrhosis	3	5
Muscle Atrophy	3	5
Non-Small-Cell Lung Carcinoma	1	5
Osteoporosis	3	5
Periodontal Diseases	1	5
Squamous cell carcinoma	4	5
Triglycerides: Elevated	3	5
Tuberculosis	1	5
Acetaminophen (Tylenol) Toxicity	2	4
Acute Myeloid Leukemia	4	4
Alcohol Toxicity	2	4
Cachexia	2	4
Down Syndrome	2	4
Kidney Fibrosis	2	4
Leukemia	3	4
Liver Damage	2	4
Liver Steatosis	2	4
Lung Injury: Acute	2	4
Sleep Disorders	2	4
Stroke: Attenuation/Recovery	2	4
Werner Syndrome	2	4
Advanced Glycation End products (AGE)	2	3
Aluminum Toxicity	2	3
Autoimmune Diseases	2	3
Breast Cancer: Chemically-Induced	2	3
Breast Cancer: Lung Metastasis	2	3
Cardiovascular Diseases	3	3
Dementia	2	3
Fibrosis	2	3
Hyperglycemia	2	3
Lipopolysaccharide-Induced Toxicity	2	3
Liver Fibrosis	2	3
Memory Disorders	2	3
Ovarian Cancer	3	3
Prostate Cancer: Prevention	2	3
Pseudomonas aeruginosa	3	3
Stress	2	3
Ultraviolet Radiation Induced Damage	2	3
Acute Respiratory Distress Syndrome	1	2
Aflatoxicosis	1	2
Amnesia	1	2
Atopic Dermatitis	1	2
Bacterial Infections	1	2
Brain Edema	1	2
Brain Hypoxia	1	2
Brain Injury: Traumatic	1	2
Cachexia: Cancer	1	2
Cachexia: Chemotherapy Induced	1	2
Cancer Mortality	1	2
Cancers: Radiation-Resistant	1	2
Candida Albicans	2	2
Cardiac Hypertrophy	1	2
Cardiomyopathy	1	2
Chemotherapy-Induced Toxicity: Cyclophosphamide	1	2
Chronic Kidney Disease (CKD)	1	2
Circadian Dysregulation	1	2
Clostridium Infections	1	2
Cocaine Withdrawal	1	2
Colitis	1	2
Demyelinating Diseases	1	2
Diabetes: Oxidative Stress	1	2
Dysbiosis: Bifidobacteria Deficiency	1	2
Encephalomyelitis	1	2
Epilepsy	1	2
Escherichia coli Infections	2	2
Fatty Liver	1	2
Fetal Origin of Adult Disease	1	2
Fish Diseases	1	2
Hearing Loss	1	2
Heart Failure	1	2
Hepatitis C	1	2
Infection: Antibiotic Resistant	2	2
Inflammatory Bowel Diseases	1	2
Intracerebral Hemorrhage	1	2
Kidney Cancer	2	2
Kidney Damage	1	2
Liver Damage: Aflatoxin-Induced	1	2
Lung Diseases	1	2
Lymphoma	1	2
Melanoma	2	2
Mercury Poisoning	1	2
Neurodegenerative Diseases	2	2
Nicotine/Tobacco Toxicity	1	2
Periodontitis	1	2
Peripheral Neuropathies	1	2
Porphyromonas gingivalis	1	2
Prediabetes	1	2
Psoriasis	1	2
Pulmonary Emphysema	1	2
Pulmonary Fibrosis	1	2
Salmonella Infections	2	2
Seizures	1	2
Sepsis	1	2
Snake Bite: Venom Toxicity	1	2
Staphylococcus aureus: Methicillin-resistant (MRSA)	2	2
Stroke	1	2
Tendon Injury	1	2
Testicular Injury: Chemical/Metal Induced	1	2
Testosterone: Too Low	1	2
Varicocele	1	2
AIDS	1	1
Aging Skin	1	1
Aging: Brain	1	1
Allergic Rhinitis	1	1
Amyotrophic lateral sclerosis (ALS)	1	1
Anxiety	1	1
Avian Influenza	1	1
Bile Duct Cancer	1	1
Blue Light Toxicity	1	1
Bone Diseases	1	1
Bone Fractures	1	1
Brain Cancer	1	1
Breast Cancer: HER-2 Overexpressed	1	1
Candidiasis: Vulvovaginal	1	1
Central Nervous System Diseases	1	1
Chemotherapy-Induced Toxicity: Cisplatin	1	1
Cholangiocarcinoma	1	1
Chronic Disease	1	1
Chronic Lymphocytic Leukemia	1	1
Chronic Myeloid Leukemia	1	1
Cytomegalovirus Infections	1	1
Depression	1	1
Diabetes Mellitus: Type 1: Prevention	1	1
Endometrial Cancer	1	1
Esophageal Cancer	1	1
Gastrointestinal Diseases	1	1
Gram-Negative Bacterial Infections	1	1
H5N1 Infection	1	1
HIV Drug-Induced Toxicity	1	1
HIV Infections	1	1
Head and Neck Cancer	1	1
Heart Disease	1	1
Helicobacter Pylori Infection	1	1
Hepatitis B	1	1
Herpes Simplex Virus Type 1	1	1
Human Papillomavirus (HPV)	1	1
Influenza	1	1
Insulin Disorders	1	1
Keloid	1	1
Lung Cancer: Prevention	1	1
Neuroblastoma	1	1
Parkinson's Disease	1	1
Pesticide Toxicity	1	1
Post-Traumatic Stress Disorders (PTSD)	1	1
Promyelocytic leukemia	1	1
Rhabdomyosarcoma	1	1
Skin Cancer	1	1
Skin Cancer: Prevention	1	1
Steptococcus Mutans Infections	1	1
Thyroid Cancer	1	1
Toxoplasma gondii Infection	1	1
Urinary Tract Infections	1	1

Name	AC	CK
Western Diet	2	4
Low Dose Ionizing Radiation	1	2
Blue Light (400−495 nm)	1	1

Name	AC	CK
Curcumin	41	56
Vitamin D	15	56
EGCG (Epigallocatechin gallate)	18	30
Sulforaphane	7	30
Vitamin C	10	27
Broccoli Sprouts	3	22
Omega-3 Fatty Acids	3	22
Cannabinoids	4	18
Thymoquinone	10	18
Fish Oil	4	16
Genistein	6	16
Ginger	6	16
Lactobacillus plantarum	4	16
Quercetin	8	16
Amurensin G	3	15
Berberine	9	15
Flavonoids	9	15
Black Raspberry	3	14
Flaxseed	3	13
Polyphenols	9	13
Delta-tetrahydrocannabinol (THC)	2	12
Water: Deuterium Depleted	2	12
Zinc	2	12
Coenzyme Q10	2	11
Garlic	2	11
Resveratrol	9	11
Alpha-Lipoic Acid	4	10
Indole-3-Carbinol	1	10
Lactobacillus gasseri	1	10
Lactobacillus rhamnosus GG	1	10
Magnesium	1	10
Myo-inositol	1	10
Passion Flower	1	10
Pycnogenol (Pine Bark)	1	10
Shilajit	1	10
Vitamin B-12	1	10
Nigella sativa (aka Black Seed)	3	9
Bacopa	4	8
Ellagic Acid	3	8
Astaxanthin	4	7
Dragon Fruit	4	7
Kaempferol	3	7
Myricetin	2	7
Propolis: Bee	2	7
Taurine	2	7
Turmeric	5	7
Anthocyanins	4	6
Cannabidiol	5	6
Ginseng (Korean)	3	6
Green Tea	4	6
Lychee	3	6
Reishi Mushroom	4	6
Royal Jelly	3	6
Rutin	3	6
Tomato	3	6
Babchi	1	5
Bisdemethoxycurcumin	1	5
Blueberry	3	5
DHA (Docosahexaenoic Acid)	4	5
Folic Acid	3	5
Mushrooms: All	1	5
Propolis: Brazillian	1	5
Walnut	3	5
Angelica	2	4
Baccharis trimera	2	4
Bee Venom	3	4
Bitter Melon	2	4
Black Currant	2	4
Cannabis	3	4
Cranberry	3	4
EPA (Eicosapentaenoic Acid)	3	4
Ferulic acid	3	4
Fucoidan	2	4
Ginsenosides	3	4
Guarana	2	4
Hesperidin	2	4
Lingonberry	2	4
Moringa oleifera	2	4
Mulberry	2	4
Puerarin	2	4
Seaweed	2	4
Shiitake Mushroom	2	4
Spirulina	2	4
Tetrahydrocurcumin	2	4
Ursolic Acid	3	4
Apigenin	2	3
Chokeberry	2	3
Coffee	2	3
Curcuminoids	2	3
Dandelion	2	3
Green Coffee Bean	2	3
Guduchi	3	3
Kimchi	2	3
Lactobacillus rhamnosus	3	3
Luteolin	3	3
Magnolia	2	3
Magnolol	2	3
Marjoram	2	3
Melatonin	2	3
Nobiletin	2	3
Onion	2	3
Piperine	2	3
Pomegranate	3	3
Shikonin	2	3
Silibinin	2	3
Strawberry	2	3
Syrian rue	2	3
Urolithin A	2	3
Vitamin K2	2	3
Wasabi	2	3
Xanthohumol	2	3
Acai	1	2
Achiote	1	2
Agaricus brasiliensis	1	2
Allicin	1	2
Aloe Vera	1	2
Apple	1	2
Astragalus	1	2
Baicalein	2	2
Bee Propolis	2	2
Beta-glucan	1	2
Betaine	1	2
Bilberry	1	2
Black Tea	1	2
Blue Honeysuckle	1	2
Brown Rice: Pre-Germinated	1	2
Burdock	1	2
Caffeic acid phenethyl ester	1	2
Capparis spinosa (caper)	1	2
Carvacrol	1	2
Celastrol	1	2
Chia	1	2
Chlorogenic Acid	1	2
Chlorophyllin	1	2
Chrysanthemum Indicum	1	2
Chrysin	2	2
Cinnamaldehyde	1	2
Cinnamon	1	2
Citrus naringin	1	2
Cocoa	1	2
Common bean	1	2
Crocin	1	2
Cryptoxanthin	1	2
Cucurbitacin B	1	2
Cucurbitacin E	2	2
Elderberry	1	2
Evening Primrose Oil	1	2
Fisetin	2	2
Flaxseed Oil	1	2
Fruit: All	1	2
Ginkgo biloba	1	2
Ginseng	1	2
Glutathione	1	2
Gotu Kola	1	2
Grape	2	2
Hemp Seed	1	2
Honey	2	2
Huaier (Trametes robiniophila murr)	2	2
Hydrogen Water	1	2
Krill	1	2
Lactobacillus probiotics	2	2
Lactobacillus salivarius	1	2
Lactoferrin	1	2
Licorice	1	2
Lignans	1	2
Litchi	1	2
Lycopene	1	2
Mucuna pruriens (aka Velvet Beans)	1	2
Naringenin	1	2
Noni leaf extract	1	2
Octacosanol	1	2
Okra	1	2
Oleanolic acid	1	2
Oligonol	1	2
Panax Notoginseng	1	2
Pantethine	1	2
Peach	1	2
Pectin	1	2
Peony	2	2
Phloretin	2	2
Pineapple	1	2
Pistachio nut	1	2
Plum	1	2
Policosanol	1	2
Pomegranate flower	1	2
Prebiotics	1	2
Probiotics	1	2
Pterostilbene	1	2
Pueraria mirifica	1	2
Red Wine	1	2
Rice Bran	1	2
Rice: Black	1	2
Rosemary	2	2
Selenium	1	2
Sesame Seed Oil	1	2
Sesamin	1	2
Solanum Glaucophyllum	1	2
Soursop	1	2
Tea: Oolong	1	2
Theophylline	1	2
Trichosanthes Kirilowii	1	2
Turmerones	1	2
Ubiquinol	1	2
Vegetables: All	1	2
Vinegar	1	2
Vitamin D3	1	2
Vitamin E	1	2
Water: Deep Sea	1	2
Whey	1	2
Wogonin	1	2
Yarrow	1	2
beta-Carotene	1	2
2,3,5,4'-tetrahydroxystilbene-2-O-β -D-glucoside (THSG)	1	1
6-Shogaol	1	1
Adlay	1	1
Antrodia camphorata	1	1
Artichoke	1	1
Ashwagandha	1	1
Astragaloside	1	1
Bacillus Clausii	1	1
Barberry	1	1
Basil	1	1
Benzyl isothiocyanate	1	1
Beta-Elemene	1	1
Black Pepper	1	1
Caffeic Acid	1	1
Camel Milk	1	1
Carnosic Acid	1	1
Catechin	1	1
Chickpea	1	1
Cruciferous Vegetables	1	1
Cucurbitacin D	1	1
Daidzein	1	1
Delphinidin	1	1
Diosgenin	1	1
Eriodictyol	1	1
Evodiamine	1	1
Fenugreek	1	1
Feverfew	1	1
Fig	1	1
Flax Straw	1	1
Folate	1	1
Frankincense	1	1
Fucoxanthin	1	1
Garcinia cambogia	1	1
Goji	1	1
Guggul	1	1
Gynostemma	1	1
Hazelnut	1	1
Hibiscus	1	1
Homeopathic Medicine: All	1	1
Honokiol	1	1
Hyperforin	1	1
Iodine	1	1
Isothiocyanates	1	1
Japanese cypress	1	1
Kahweol	1	1
Lactobacillus paracasei	1	1
Lactobacillus reuteri	1	1
Lavender: Essential Oil	1	1
Lettuce	1	1
Lichens	1	1
Lotus	1	1
Lupeol	1	1
Lysergic Acid Diethylamide (LSD)	1	1
Mangiferin	1	1
Mangosteen	1	1
Manuka Honey	1	1
Maple Syrup	1	1
Maqui	1	1
Mugwort	1	1
Mustard Oil	1	1
Oleocanthal	1	1
Oleuropein	1	1
Olive leaf extract	1	1
Patchouli	1	1
Peppermint	1	1
Perilla	1	1
Polyunsaturated Fatty Acids (PUFAs)	1	1
Prickly Pear Cactus	1	1
Psilocybin	1	1
Psychedelics:All	1	1
Pumpkin	1	1
Rooibos	1	1
Rose	1	1
Rosmarinic acid	1	1
Sea buckthorn	1	1
St. Johns Wort	1	1
Sweet Potato	1	1
Sweet Potato: Purple	1	1
Tamarind	1	1
Tanshinone IIA	1	1
Theanine	1	1
Thiamine (B-1)	1	1
Thymol	1	1
Vitamin E: Gamma-tocotrienol	1	1
Yellow Sweet Clover (Melilotus officinalis)	1	1
Yerba Mate	1	1

Name	AC	CK
Meditation	4	31
Yogic Technique: Sudarshan kriya	2	20
Exercise	5	18
Mindfullness Training	2	11
Exercise: Aerobic	1	10
Exercise: Endurance	1	10
Spa Bathing	1	10
Yoga	1	10
Light-Emitting Diodes (LEDs) Therapy	2	7
Laser Treatment: Low-Level	2	3
Hyperbaric Treatment	1	2
Aromatherapy	1	1

Name	AC	CK
Anti-Inflammatory Agents	81	268
Apoptotic	68	137
Antioxidants	58	120
Antiproliferative	72	118
Immunomodulatory	23	67
Tumor Necrosis Factor (TNF) Alpha Inhibitor	25	67
Cell cycle arrest	33	61
Chemopreventive	38	60
Hypolipidemic	27	60
Hepatoprotective	31	57
MicroRNA modulator	24	57
Neuroprotective Agents	28	47
Anticholesteremic Agents	16	46
Anti-metastatic	30	43
NF-kappaB Inhibitor	22	43
Anticarcinogenic Agents	24	38
Hypoglycemic Agents	11	36
Chemotherapeutic	17	35
Antineoplastic Agents	9	27
Nrf2 activation	7	23
Cyclooxygenase 2 Inhibitors	10	22
Anti-Apoptotic	7	21
Interleukin-8 downregulation	2	20
Angiogenesis Inhibitors	7	18
Vascular Endothelial Growth Factor Inhibitors	7	18
Cardioprotective	9	16
Interleukin-6 Downregulation	9	16
Chemosensitizer	7	15
Interleukin-1 beta downregulation	7	14
Renoprotective	7	13
Histone deacetylase inhibitor	2	12
Enzyme Inhibitors	5	11
Anti Inflammatory	1	10
Gastrointestinal Agents	5	10
Interleukin-12 downregulation	1	10
Interleukin-23 Downregulation	1	10
Antimicrobial	7	9
Superoxide Dismutase Up-regulation	5	9
Anti-Adipogenic	3	8
Anti-Bacterial Agents	8	8
Malondialdehyde Down-regulation	4	8
Anti-Tumor	2	7
Antiviral Agents	6	7
Hypoxia-inducible factor-1 (HIF-1) inhibitor	2	7
Vascular Endothelial Growth Factor A Inhibitor	2	7
Anti-Angiogenic	2	6
Anti-atherogenic	3	6
Genoprotective	3	6
Heme oxygenase-1 up-regulation	4	6
Wnt/β-catenin signaling pathway modulation	4	6
Anti-Fibrotic	3	5
Autophagy Up-regulation	1	5
Cytoprotective	1	5
Insulin Sensitizers	3	5
Matrix metalloproteinase-2 (MMP-2) inhibitor	5	5
Matrix metalloproteinase-9 (MMP-9) inhibitor	5	5
Autophagy Inhibitors	3	4
Chemoprotective Agents	2	4
Chondroprotective	2	4
Cytotoxic	3	4
Detoxifier	2	4
Fibroblast growth factor 21 upregulation	2	4
Gastroprotective	2	4
Matrix metalloproteinase-3 (MMP-3) inhibitor	2	4
Nitric Oxide Inhibitor	3	4
Pancreato Protective Agents	3	4
Remyelination	2	4
Tumor Suppressor Protein p53 Upregulation	4	4
Antihypertensive Agents	2	3
Antioxidant Effects	2	3
Bcl-2 protein down-regulation	3	3
Catalase Up-Regulation	2	3
DNA Repair Up-regulation	2	3
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor	2	3
Insulin-releasing	2	3
NF-E2-Related Factor-2 (Nrf2) Modulator	3	3
Osteoprotective	2	3
Prophylactic Agents	2	3
Adiponectin Down-Regulation	1	2
Androgen Antagonists	1	2
Anti-Glycation Agents	1	2
Anticonvulsants	1	2
Antidepressive Agents	1	2
Appetite Depressants	1	2
Brain-derived neurotrophic factor modulator	1	2
Cyclooxygenase Inhibitors	1	2
Enzyme Activators	1	2
Immunomodulatory: Th17 downregulation	1	2
Immunostimulatory	1	2
Interferon Gamma Reducer	1	2
Interleukin-10 upregulation	1	2
Interleukin-17 downregulation	1	2
Matrix Metalloproteinase-13 (MMP-13) Inhibitor	1	2
Matrix Metalloproteinases Inhibitors	1	2
Matrix metalloproteinase-1 (MMP-1) inhibitor	1	2
Osteogenic	1	2
Phase I Detoxification Enzyme Inducer	1	2
Phase II Detoxification Enzyme Inducer	1	2
Proteasome Inhibitors	1	2
Radioprotective	1	2
Radiosensitizer	2	2
SIRT1 Activator	1	2
STAT3 Inhibitor	2	2
Transforming growth factor beta (TGF-β) upregulation	1	2
anti-inflammatory	1	2
Acetylcholinesterase Inhibitor	1	1
Anti-Allergic Agents	1	1
Anti-Infective Agents	1	1
Antioxidant	1	1
Antiparasitic Agents	1	1
Cyclin D1 Down-Regulation	1	1
Cyclin-dependent kinase inhibitor: P16INK4	1	1
Estradiol Antagonists	1	1
Glutathione S-transferase Inhibitor	1	1
Glycogen synthase kinase-3beta (GSK-3beta) Inhibitor	1	1
Interleukin-10 downregulation	1	1
Neurogenesis	1	1
P16 Activation	1	1
P21 Activation	1	1
Phosphodiesterase Inhibitors	1	1
Photoprotective	1	1
Quorum Sensing Inhibition	1	1
Survivin Down-Regulation	1	1
Telomerase Inhibitor	1	1
Transforming growth factor beta (TGF-β) inhibitor	1	1
Vasodilator Agents	1	1
Vitamin D Receptor (VDR) Modulator	1	1

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2016 ;11(4):e0152895. Epub 2016 Apr 12. PMID: 27071063

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Broccoli Sprouts, Sulforaphane

Diseases : Anemia: Sickle Cell

Additional Keywords : Gene Expression Regulation

[+]

Concurrent alteration in inflammatory biomarker gene expression and oxidative stress: how aerobic training and vitamin D improve T2DM.Jun 21, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Complement Med Ther. 2022 Jun 22 ;22(1):165. Epub 2022 Jun 22. PMID: 35733163

Ginger can improve rheumatoid arthritis by decreasing disease manifestations in patients.May 24, 2019

Click here to read the entire abstract

Pubmed Data : Gene. 2019 May 25 ;698:179-185. Epub 2019 Mar 4. PMID: 30844477

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Sci Rep. 2021 Feb 17 ;11(1):3972. Epub 2021 Feb 17. PMID: 33597583

Article Published Date : Feb 16, 2021

Study Type : Human Study

Additional Links

Substances : Lactobacillus plantarum

Diseases : Coronary Artery Disease, Endothelial Dysfunction

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Interleukin-8 downregulation

Additional Keywords : Gene Expression Regulation

[+]

Lactobacillus rhamnosus SP1 normalises skin expression of genes implicated in insulin signalling and improves adult acne.Nov 29, 2016

Click here to read the entire abstract

Pubmed Data : Benef Microbes. 2016 Nov 30 ;7(5):625-630. Epub 2016 Sep 6. PMID: 27596801

Article Published Date : Nov 29, 2016

Study Type : Human Study

Additional Links

Diseases : Acne

Additional Keywords : Gene Expression Regulation

[+]

Magnesium and zinc co-supplementation for 12 weeks among women with PCOS had beneficial effects on inflammation and oxidative stress. Nov 09, 2017

Sudarshan Kriya practice may exert effects on immunity, aging, cell death, and stress regulation through transcriptional regulation.Jan 31, 2008

Click here to read the entire abstract

Pubmed Data : J Psychosom Res. 2008 Feb ;64(2):213-8. PMID: 18222135

Article Published Date : Jan 31, 2008

Study Type : Human Study

Additional Links

Diseases : Aging, DNA damage, Oxidative Stress

Therapeutic Actions : Yogic Technique: Sudarshan kriya

Pharmacological Actions : Anti-Apoptotic, Antioxidants

Additional Keywords : Gene Expression Regulation

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Sulforaphane treatment resulted in a significant reduction in specific airway resistance and also increased small airway luminal area.Dec 31, 2014

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Pubmed Data : Cell Mol Biol (Noisy-le-grand). 2022 May 31 ;68(5):7-15. Epub 2022 May 31. PMID: 36029489

Article Published Date : May 30, 2022

Study Type : Human Study

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Substances : Vitamin D

Diseases : Inflammation, Kidney Failure: Chronic, Oxidative Stress, Vitamin D Deficiency

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Malondialdehyde Down-regulation, NF-kappaB Inhibitor

Additional Keywords : Gene Expression Regulation

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Vitamin D supplementation may have a beneficial role in ulcerative colitis patients.Jun 30, 2016

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Berberine can significantly inhibit the activity of N-acetyltransferase in human lung cancer cell line A549.May 31, 2014

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Pubmed Data : J Tradit Chin Med. 2014 Jun ;34(3):302-8. PMID: 24992757

Article Published Date : May 31, 2014

Study Type : Human In Vitro

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Substances : Berberine

Diseases : Lung Cancer

Pharmacological Actions : Antineoplastic Agents, Enzyme Inhibitors, MicroRNA modulator

Additional Keywords : Chinese Herbs, Gene Expression Regulation

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Bisdemethoxycurcumin induced changes in gene expression that may reveal cytotoxic information on the genetic level.Jan 10, 2015

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Pubmed Data : In Vivo. 2015 11-12;29(6):711-728. PMID: 26546528

verticillin A from Verticillium-infected wild mushrooms as a potent anti-cancer agent that effectively suppresses 5-FU-resistant human colon cancer cells. Aug 31, 2015

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Pubmed Data : Genom Data. 2015 Sep 1 ;5:189-191. PMID: 26309812

Article Published Date : Aug 31, 2015

Study Type : Human In Vitro

Additional Links

Substances : Mushrooms: All

Diseases : Colon Cancer

Pharmacological Actions : Apoptotic, Cell cycle arrest, Chemotherapeutic

Additional Keywords : Chemothapeutic Synergy: 5-flourouracil, Epigenetic Modification In Cancer, Gene Expression Regulation

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Vitamin C modulated the immune system.Mar 22, 2017

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Pubmed Data : BMC Genomics. 2017 Mar 23 ;18(1):252. Epub 2017 Mar 23. PMID: 28335738

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Pubmed Data : Lipids. 2016 Aug 16. Epub 2016 Aug 16. PMID: 27531126

Article Published Date : Aug 15, 2016

Study Type : Animal Study

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Substances : Alpha-Lipoic Acid

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Hypolipidemic

Additional Keywords : Gene Expression Regulation

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Alternating consumption of β-glucan and quercetin reduces mortality in mice with colorectal cancer.Sep 30, 2019

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Pubmed Data : Food Sci Nutr. 2019 Oct ;7(10):3273-3285. Epub 2019 Sep 4. PMID: 31660141

Article Published Date : Sep 30, 2019

Study Type : Animal Study

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Substances : Beta-glucan, Quercetin

Diseases : Cancer Mortality, Colorectal Cancer

Pharmacological Actions : Anti-Inflammatory Agents, Chemotherapeutic, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Gene Expression Regulation

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Ameliorative effects of high intensity interval training and Lactobacillus rhamnosus GG Protect against tetracycline-induced fatty liver.Dec 31, 2021

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Pubmed Data : EXCLI J. 2022 ;21:991-1006. Epub 2022 Jul 21. PMID: 36110559

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Lactobacillus rhamnosus GG

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Exercise

Pharmacological Actions : Anti-Inflammatory Agents, Matrix metalloproteinase-1 (MMP-1) inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor

Additional Keywords : Gene Expression Regulation

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An antioxidant-rich extract of seaweed polyphenols combined with current PC treatment modalities may inhibit tumor relapse by targeting therapy-orchestrated autophagy in residual cells.Dec 31, 2014

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Pubmed Data : World J Gastroenterol. 2015 Sep 21 ;21(35):10091-103. PMID: 26401074

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Pubmed Data : Exp Ther Med. 2014 Jul ;8(1):260-266. Epub 2014 May 16. PMID: 24944632

Article Published Date : Jun 30, 2014

Study Type : Animal Study

Additional Links

Substances : Curcumin, Piperine

Diseases : High Fat Diet, Hyperlipidemia, Triglycerides: Elevated

Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic

Additional Keywords : Gene Expression Regulation, Natural Substance Synergy

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Coffee modulates the transcription of genes related to prostate cancer and inflammation.Sep 02, 2015

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Pubmed Data : J Nutr Biochem. 2015 Sep 3. Epub 2015 Sep 3. PMID: 26419686

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Pubmed Data : J Nutr. 2016 Mar 9. Epub 2016 Mar 9. PMID: 26962192

Article Published Date : Mar 08, 2016

Study Type : Animal Study

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Substances : Selenium

Diseases : Liver Damage: Aflatoxin-Induced

Pharmacological Actions : Hepatoprotective

Additional Keywords : Gene Expression Regulation

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Dietary supplementation with dried plum may prevent the skeletal effects of radiation exposures either in space or on Earth.Dec 31, 2015

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Pubmed Data : Mult Scler Relat Disord. 2022 Dec 16 ;70:104471. Epub 2022 Dec 16. PMID: 36580874

Article Published Date : Dec 15, 2022

Study Type : Animal Study

Additional Links

Substances : Carvacrol

Diseases : Multiple Sclerosis

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation

Additional Keywords : Gene Expression Regulation

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Effects of the clock modulator nobiletin on circadian rhythms and pathophysiology in female mice of an Alzheimer's disease model.Jul 08, 2021

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Pubmed Data : Fish Shellfish Immunol. 2017 Jun 22. Epub 2017 Jun 22. PMID: 28648884

Article Published Date : Jun 21, 2017

Study Type : Animal Study

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Substances : EGCG (Epigallocatechin gallate)

Diseases : Fish Diseases

Additional Keywords : Gene Expression Regulation

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EGCG modulates the reversal of gene silencing involved in colon carcinogenesis.May 05, 2016

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Pubmed Data : Oncotarget. 2016 May 6. Epub 2016 May 6. PMID: 27167203

Article Published Date : May 05, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Colon Cancer

Pharmacological Actions : Anticarcinogenic Agents, Chemopreventive

Additional Keywords : Dose Response, Epigenetic Modification In Cancer, Gene Expression Regulation

[+]

EGCG supplement specifically counteracts daytime overeating induced by high fat diet in mice.Jul 27, 2016

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Pubmed Data : Mol Nutr Food Res. 2016 Jul 28. Epub 2016 Jul 28. PMID: 27468160

Article Published Date : Jul 27, 2016

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : High Fat Diet

Pharmacological Actions : Appetite Depressants

Additional Keywords : Gene Expression Regulation

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View the Evidence: 579 Abstracts with Gene Expression Regulation Research

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1,25-dihydroxyvitamin D3 induces stable and reproducible therapeutic tolerogenic dendritic cells with specific epigenetic modifications.Dec 31, 2020

Acute effects of the consumption of Passiflora setacea juice on metabolic risk factors and gene expression profile in humans.Apr 15, 2020

Aerobic exercise-training down-regulated pro-inflammatory genes, but up-regulated anti-inflammatory, neuron survival and axon growth-related genes.Aug 31, 2015

B12 supplementation influences regulation of several metabolically important Type 2 diabetes-associated genes through methylation of miR21.Nov 13, 2017

Brain education-based meditation helps lower LDL cholesterol level and the inflammatory gene expression in patients with hypertension or T2D.Apr 30, 2019

Broccoli sprout homogenate is safe in stable SCD patients and may induce changes in gene expression levels.Dec 31, 2015

Concurrent alteration in inflammatory biomarker gene expression and oxidative stress: how aerobic training and vitamin D improve T2DM.Jun 21, 2022

CoQ10 intake for 12 weeks in PCOS women significantly improved gene expression of LDLR, PPAR-γ, IL-1, IL-8 and TNF-α.Sep 25, 2017

Delta9-tetrahydrocannabinol administration led to the inhibition of the VEGF Pathway in Two Patients with Glioblastoma Multiforme.Aug 14, 2004

Diospyros peregrina fruit preparation mediated immunomodulation of lymphocytes isolated from the blood of breast cancer patients.Dec 31, 2020

Endurance training positively affects thousands of DNA methylation sites and genes which leads to improvement in muscle function and health.Dec 01, 2014

Fish oil supplementation for 6 weeks in women with gestational diabetes significantly improved gene expression of PPAR-γ, IL-1, and TNF-α.Jan 30, 2018

Ginger can improve rheumatoid arthritis by decreasing disease manifestations in patients.May 24, 2019

Indole-3-carbinol could modulate the gene expression involved in wound healing in systemic lupus erythematosus cases and healthy controls.Jun 30, 2020

Lactobacillus gasseri CP2305 administration is a potential candidate therapeutic option for patients with IBS.Dec 31, 2016

Lactobacillus plantarum 299v probiotic supplementation in men with stable coronary artery disease suppresses systemic inflammation.Feb 16, 2021

Lactobacillus rhamnosus SP1 normalises skin expression of genes implicated in insulin signalling and improves adult acne.Nov 29, 2016

Magnesium and zinc co-supplementation for 12 weeks among women with PCOS had beneficial effects on inflammation and oxidative stress. Nov 09, 2017

Maternal gene expression changes during pregnancy and that these changes are related to vitamin D levels.Dec 31, 2015

Metabolised pycnogenol induces apoptosis in human fibrosarcoma cells.Mar 31, 2015

Mindfulness meditation reduces intraocular pressure, lowers stress biomarkers and modulates gene expression in glaucoma.Nov 30, 2018

Omega-3 fatty acids supplementation for 12 weeks in PCOS women significantly improved gene expression of PPAR-γ and LDLR.Feb 23, 2017

Omega-3 fatty acids supplementation for 6 weeks to women with gestational diabetes mellitus had beneficial effects.Jan 05, 2020

Oral Shilajit supplementation in adult overweight/class I obese human subjects promoted skeletal muscle adaptation.Jun 30, 2016

Prolonged periods of sedentary behavior are associated with significantly lower BRCA1 mRNA expression.Nov 01, 2015

Rapid changes in histone deacetylases and inflammatory gene expression in expert meditatorsJan 31, 2014

Spa therapy induces clinical improvement and protein changes in patients with chronic back pain.Oct 23, 2019

Sudarshan Kriya practice may exert effects on immunity, aging, cell death, and stress regulation through transcriptional regulation.Jan 31, 2008

Sulforaphane treatment resulted in a significant reduction in specific airway resistance and also increased small airway luminal area.Dec 31, 2014

Suppression of pro-inflammatory and pro-survival biomarkers in oral cancer patients consuming a black raspberry phytochemical-rich troche.Dec 22, 2015

Taking myo-inositol by women with PCOS had beneficial effects on glycemic control, triglycerides and VLDL-cholesterol levels, and gene expression of PPAR-γ.Jan 03, 2019

The bioactivity of garlic is multifaceted and includes activation of genes related to immunity, apoptosis, and xenobiotic metabolism in humans and Mono Mac 6 cells.Sep 29, 2015

The effect of genistein on lipid levels and LDLR, LXRα and ABCG1 expression in postmenopausal women with hyperlipidemia.Dec 31, 2018

The median survival time of patients in the deuterium depleted water consuming group was 2-4 times longer than it is generally observed in lung cancer patients.Dec 31, 2012

Third-trimester high-dose vitD3 supplementation in healthy pregnant women had balanced effects on biomarkers of cord blood Th1 and Th2 responses.Dec 31, 2015

Transcriptomic profile of whole blood cells from elderly subjects fed probiotic bacteria Lactobacillus rhamnosus GG.Dec 31, 2015

ubiquinol decreases monocytic expression and DNA methylation of the pro-inflammatory CXCL2 gene in humans.Sep 30, 2012

Upregulation of vitamin D-related genes in schizophrenic patients.Dec 31, 2017

Vitamin C supplementation has beneficial effects for the male partners of couples with recurrent pregnancy loss could lead to improved pregnancy outcomes.Feb 29, 2020

Vitamin D reduces clinical and metabolic symptoms in end-stage renal disease.May 30, 2022

Vitamin D supplementation may have a beneficial role in ulcerative colitis patients.Jun 30, 2016

Yogic practices have rapid effects at the molecular level in circulating immune cells.Dec 31, 2012

Alpha-lipoic acid could be a therapeutic agent because of its inhibitory effects on ROS production, inflammation, and adipose tissue expansionDec 31, 2015

Amurensin G augmented the cytotoxic and apoptotic effects of TRAIL in TRAIL resistant leukemic cells.Jul 31, 2012

Amurensin G had significant antiangiogenic and antitumor growth effects in tamoxifen resistant breast cancer.Sep 30, 2012

Amurensin G. was a potent SIRT1 Inhibitor which led to the down regulation of multidrug resistance.Oct 31, 2010

Berberine can significantly inhibit the activity of N-acetyltransferase in human lung cancer cell line A549.May 31, 2014

Bisdemethoxycurcumin induced changes in gene expression that may reveal cytotoxic information on the genetic level.Jan 10, 2015

In utero bisphenol A exposure is linked with sex specific changes in the transcriptome and methylome of human amniocytes.Sep 18, 2019

LED irradiation promoted elastin gene expression more in elderly than in younger adults.Mar 31, 2016

Malaysian and Brazilian red propolis show potential to assist in wound healing.Dec 31, 2014

Psoralea corylifolia induces apoptosis and autophagy and alteres genes expression assayed by cDNA microarray in human prostate cancer PC-3 cells.Jun 30, 2018

Sulforaphane regulates xenobiotic metabolism phase II and III enzymes differently in colorectal cancer and untransformed epithelial colon cells.Oct 31, 2016

Taurine ameliorates particulate matter-induced emphysema by switching on mitochondrial NADH dehydrogenase genes.Oct 24, 2017

The proapoptotic effect of cannabinoids on tumor cells is mediated by a ceramide dependent upregulation of the stress protein p8.Mar 31, 2006

These results provide important new data for ellagic acid in anti-colorectal carcinoma research.Jan 31, 2017

Thymoquinone-rich fractions of Nigella sativa could be an alternative to combat oxidative stress insults in neurodegenerative diseases.Dec 31, 2015

verticillin A from Verticillium-infected wild mushrooms as a potent anti-cancer agent that effectively suppresses 5-FU-resistant human colon cancer cells. Aug 31, 2015

Vitamin C modulated the immune system.Mar 22, 2017

Albiflorin ameliorates obesity by inducing thermogenic genes.Dec 31, 2016

In vitro and in vivo anti-lung cancer activity of emodin: A RNA-seq transcriptome analysis.Sep 20, 2022

10% pectin supplementation for one month in adult rats decreases body-fat content and ameliorates age-related insulin and leptin resistance.Jul 21, 2015

5-FU and thymoquinone combination therapy resulted in a more significant reduction on AOM-induced colorectal tumors.Dec 31, 2015

A cucurbitane type triterpenoid compound from Momordica charantia alleviated diabetic metabolic symptoms in alloxan induced diabetic mice.Oct 31, 2016

A hot water extract from wasabi leaves induces mild suppression of obesity in a high-fat diet induced mice.Jul 31, 2013

A Polysaccharide from black current is effective in preventing and alleviating the development of atopic dermatitis-like skin disease.Dec 31, 2017

A thymoquinone-rich fraction extracted from Nigella sativa effectively improved the plasma and liver antioxidant capacity.Feb 28, 2010

A. brasiliensis improves the serum lipid profile in hypercholesterolemic rats May 04, 2016

Achillea Millefolium hydro alcoholic extract protects pancreatic cells.Dec 31, 2013

Additive effect of walnut and chokeberry on regulation of antioxidant enzyme gene expression and attenuation of lipid peroxidation.Oct 03, 2018

Administering ubiquinol 30 min before traumatic brain injury significantly affected cerebral gene expression profiles.Jun 30, 2017

Administration of Moringa oleifera extract mitigated cyclophosphamide-induced testicular damage.May 14, 2020

Gene Expression Regulation

View the Evidence:
579 Abstracts with Gene Expression Regulation Research