HLA-DQ2/DQ8

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3 Problem Substances Researched for HLA-DQ2/DQ8

Name	AC	CK
Gluten	6	7
Gliadin	2	3
Insulin	1	1

4 Diseases Researched for HLA-DQ2/DQ8

Name	AC	CK
Celiac Disease	8	27
Autoimmune Diseases	1	1
Diabetes Mellitus: Type 1	1	1
Epilepsy: With Cerebral Calcifications	1	1

1 Adverse Pharmacological Actions Researched for HLA-DQ2/DQ8

Name	AC	CK	Focus
Inflammatory	1	2

1 Substances Researched for HLA-DQ2/DQ8

Name	AC	CK	Focus
Vitamin A	1	2

1 Therapeutic Actions Researched for HLA-DQ2/DQ8

Name	AC	CK	Focus
Dietary Modification: Wheat/Gluten Free	4	4

2 Pharmacological Actions Researched for HLA-DQ2/DQ8

Name	AC	CK	Focus
Antiproliferative	1	10
Apoptotic	1	10

Research Articles 6
Cumulative Knowledge Score 9
Overall Research Rating GOOD

View the Evidence:
6 Abstracts with HLA-DQ2/DQ8 Research

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[+]

HLA-DQ2/8 genes may not cause gluten-associated villous atrophy, rather, be activated as a consequence of the pathological process. Dec 31, 2004

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Pubmed Data : Clin Chem Lab Med. 2005 ;43(7):685-95. PMID: 16207126

Article Published Date : Dec 31, 2004

Study Type : Human Study

Additional Links

Diseases : Celiac Disease

Pharmacological Actions : Antiproliferative , Apoptotic

Additional Keywords : HLA-DQ2/DQ8, Questions Of Causality

[+]

Results indicate that the major genetic susceptibility locus, HLA DQ, does not determine the exact clinical outcome of coeliac disease.Nov 30, 2002

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Pubmed Data : Dig Liver Dis. 2002 Dec ;34(12):842-5. PMID: 12643291

Article Published Date : Nov 30, 2002

Study Type : Human Study

Additional Links

Diseases : Celiac Disease

Additional Keywords : HLA-DQ2/DQ8

[+]

Retinoic Acid (a Vitamin A metabolite) in conjunction with IL-15 promotes rather than prevents Inflammation in CeliacsMar 09, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nature. 2011 Mar 10 ;471(7337):220-4. Epub 2011 Feb 9. PMID: 21307853

Article Published Date : Mar 09, 2011

Study Type : Transgenic Animal Study

Additional Links

Substances : Vitamin A

Diseases : Celiac Disease

Additional Keywords : Celiac Disease, HLA-DQ2/DQ8, IL-15

Problem Substances : Gliadin, Gluten

Adverse Pharmacological Actions : Inflammatory

[+]

Associations between celiac disease and type 1 diabetes: 4.4-11.1% of type 1 diabetes patients also have co-existing celiac disease as compared to 0.5% of the general population. The effects of a gluten-free diet are discussed.Mar 25, 2012

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Ital J Pediatr. 2012 Mar 26 ;38(1):10. Epub 2012 Mar 26. PMID: 22449104

Article Published Date : Mar 25, 2012

Study Type : Review

Additional Links

Diseases : Celiac Disease, Diabetes Mellitus: Type 1

Therapeutic Actions : Dietary Modification: Wheat/Gluten Free

Additional Keywords : Genotype, Glycemic Index, HLA-DQ2/DQ8

Problem Substances : Gluten, Insulin

[+]

Celiac disease: strong association to HLA and 39 nonHLA risk genes, mostly immune-related Oct 31, 2010

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Pubmed Data : Trends Mol Med. 2010 Nov ;16(11):537-50. Epub 2010 Oct 12. PMID: 20947431

Article Published Date : Oct 31, 2010

Study Type : Review

Additional Links

Diseases : Autoimmune Diseases, Celiac Disease

Therapeutic Actions : Dietary Modification: Wheat/Gluten Free

Additional Keywords : Genetic Testing, HLA-DQ2/DQ8, Intestinal Inflammation

Problem Substances : Gluten

[+]

GFD beneficial in HLA-related celiac disease with epilepsy and cerebral calcificationsMar 31, 2005

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Pubmed Data : Brain Dev. 2005 Apr ;27(3):189-200. PMID: 15737700

Article Published Date : Mar 31, 2005

Study Type : Review

Additional Links

Diseases : Celiac Disease, Epilepsy: With Cerebral Calcifications

Therapeutic Actions : Dietary Modification: Wheat/Gluten Free

Additional Keywords : HLA-DQ2/DQ8, Seizures

Problem Substances : Gliadin, Gluten

Research Articles 6
Cumulative Knowledge Score 9
Overall Research Rating GOOD

HLA-DQ2/DQ8 Related Articles

A Gluten for Punishment: the Whole Grain Assault on Health

Written by Nathan Daley, MD, MPH

Are grains toxic for everyone? Is gluten-free enough to protect your health?

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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Focus Your Research

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View the Evidence: 6 Abstracts with HLA-DQ2/DQ8 Research

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HLA-DQ2/8 genes may not cause gluten-associated villous atrophy, rather, be activated as a consequence of the pathological process. Dec 31, 2004

Click here to read the entire abstract

Results indicate that the major genetic susceptibility locus, HLA DQ, does not determine the exact clinical outcome of coeliac disease.Nov 30, 2002

Click here to read the entire abstract

Retinoic Acid (a Vitamin A metabolite) in conjunction with IL-15 promotes rather than prevents Inflammation in CeliacsMar 09, 2011

Click here to read the entire abstract

Associations between celiac disease and type 1 diabetes: 4.4-11.1% of type 1 diabetes patients also have co-existing celiac disease as compared to 0.5% of the general population. The effects of a gluten-free diet are discussed.Mar 25, 2012

Click here to read the entire abstract

Celiac disease: strong association to HLA and 39 nonHLA risk genes, mostly immune-related Oct 31, 2010

Click here to read the entire abstract

GFD beneficial in HLA-related celiac disease with epilepsy and cerebral calcificationsMar 31, 2005

Click here to read the entire abstract

HLA-DQ2/DQ8 Related Articles

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HLA-DQ2/DQ8

View the Evidence:
6 Abstracts with HLA-DQ2/DQ8 Research