Increased Bioavailability

Name	AC	CK	Focus
Glibenclamide	1	2
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	1	2

Name	AC	CK
High Fat Diet	3	6
Colon Cancer	3	5
Breast Cancer	2	2
Cognitive Decline/Dysfunction	1	2
Depressive Disorder	1	2
Gallstones	1	2
High Cholesterol	1	2
Inflammation	1	2
Liver Cancer	1	2
Obesity	1	2
Oxidative Stress	1	2
Stress	1	2
Vitamin D Deficiency	1	2
Breast Cancer: Triple Negative	1	1
Cardiac Hypertrophy	1	1
Hydrogen Peroxide Induced Toxicity	1	1

Name	AC	CK
Curcumin	15	31
Sulforaphane	2	20
Piperine	7	11
Broccoli	1	10
Coenzyme Q10	1	10
Miso	1	10
Mustard Seeds	1	10
Soup	1	10
Vitamin C	3	5
EGCG (Epigallocatechin gallate)	4	4
Apple Cider Vinegar	1	2
Caffeic Acid	1	2
Emodin	1	2
FOS (Fructooligosaccharides)	1	2
Ferulic acid	1	2
Flavonoids	1	2
Gallic Acid	1	2
Ginsenosides	1	2
Glutathione	1	2
Guduchi	1	2
Quercetin	2	2
Resveratrol	1	2
Rosmarinic acid	1	2
Vitamin D	1	2
White Pepper	1	2
Black Raspberry Seed	1	1
Black Tea	1	1
Citric Acid	1	1
Green Tea	1	1
Kaempferol	1	1
Lycopene	1	1
Myricetin	1	1
NAC (N-acetyl-L-cysteine)	1	1
Polyphenols	1	1
Silibinin	1	1
Tanshinone IIA	1	1
Tea: Oolong	1	1
Turmeric	1	1
Whey	1	1
White Tea	1	1
Yellow Tea	1	1
Yoghurt	1	1

Name	AC	CK
Interleukin-17 downregulation	1	10
Antioxidants	4	6
Antiproliferative	2	3
Anti-Inflammatory Agents	1	2
Antidepressive Agents	1	2
Chemotherapeutic	2	2
Gastrointestinal Agents	1	2
Hepatoprotective	1	2
Hypolipidemic	1	2
NF-kappaB Inhibitor	1	2
Neuroprotective Agents	1	2
Renoprotective	1	2
Anti-Apoptotic	1	1
Cardioprotective	1	1
Chemopreventive	1	1

[+]

Miso soup consumption enhances the bioavailability of the reduced form of supplemental coenzyme Q10.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Nutr Metab. 2020 ;2020:5349086. Epub 2020 Jan 7. PMID: 31998536

Article Published Date : Dec 31, 2019

Study Type : Human Study

Additional Links

Substances : Coenzyme Q10, Miso , Soup

Additional Keywords : Increased Bioavailability

[+]

Supplementation of the diet by exogenous myrosinase via mustard seeds to increase the bioavailability of sulforaphane.Aug 31, 2018

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2018 Sep ;62(18):e1700980. Epub 2018 Jul 26. PMID: 29806738

Article Published Date : Aug 31, 2018

Study Type : Human Study

Additional Links

Substances : Mustard Seeds, Sulforaphane

Additional Keywords : Increased Bioavailability

[+]

The bioavailability of sulforaphane from glucoraphanin supplements was equal to that from broccoli sprouts.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2015 ;10(11):e0140963. Epub 2015 Nov 2. PMID: 26524341

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Broccoli, Sulforaphane

Additional Keywords : Food Vs. Supplement, Increased Bioavailability, Plant Extracts

[+]

Transmucosal administration of microgranular curcumin leads to enhanced curcumin bioavailability.Nov 30, 2015

Click here to read the entire abstract

Pubmed Data : Anticancer Res. 2015 Dec ;35(12):6411-8. PMID: 26637850

Article Published Date : Nov 30, 2015

Study Type : Human Study

Additional Links

Substances : Curcumin

Pharmacological Actions : Interleukin-17 downregulation

Additional Keywords : Increased Bioavailability

[+]

A combination of piperine and ferulic acid might be an alternative therapy in the treatment of psychiatric disorders with high efficacy and low side effects.Jul 29, 2015

Click here to read the entire abstract

Pubmed Data : Metab Brain Dis. 2015 Jul 30. Epub 2015 Jul 30. PMID: 26220010

Article Published Date : Jul 29, 2015

Study Type : Animal Study

Additional Links

Substances : Ferulic acid, Piperine

Diseases : Depressive Disorder

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Increased Bioavailability, Natural Substance Synergy

[+]

Apple cider vinegar induced a protective effect against erythrocyte, kidney, and liver oxidative injury, and lowered the serum lipid levels in mice fed high cholesterol.Jul 31, 2014

Click here to read the entire abstract

Pubmed Data : J Membr Biol. 2014 Aug ;247(8):667-73. Epub 2014 Jun 4. PMID: 24894721

Article Published Date : Jul 31, 2014

Study Type : Animal Study

Additional Links

Substances : Apple Cider Vinegar

Diseases : High Cholesterol, High Fat Diet

Pharmacological Actions : Antioxidants, Hepatoprotective, Hypolipidemic, Renoprotective

Additional Keywords : Increased Bioavailability

[+]

Baicalin enhanced oral bioavailability of sorafenib in rats by inducing intestine absorption.Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2021 ;12:761763. Epub 2021 Nov 8. PMID: 34819863

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Flavonoids

Diseases : Liver Cancer

Pharmacological Actions : Gastrointestinal Agents

Additional Keywords : Chemothapeutic Synergy: Sorafenib, Increased Bioavailability

[+]

Co-administration of antioxidant significantly increased plasma level of curcumin in animal models.Nov 25, 2015

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2015 Nov 26. Epub 2015 Nov 26. PMID: 26608515

Article Published Date : Nov 25, 2015

Study Type : Animal Study

Additional Links

Substances : Caffeic Acid, Curcumin, Gallic Acid, Rosmarinic acid, Vitamin C

Diseases : Colon Cancer

Pharmacological Actions : Antioxidants, Antiproliferative

Additional Keywords : Increased Bioavailability, Metabolites

[+]

Colon targeted curcumin microspheres laden with ascorbic acid for bioavailability enhancement.Jul 15, 2018

Click here to read the entire abstract

Pubmed Data : J Microencapsul. 2018 Jul 16:1-28. Epub 2018 Jul 16. PMID: 30010458

Article Published Date : Jul 15, 2018

Study Type : Animal Study

Additional Links

Substances : Curcumin, Vitamin C

Diseases : Colon Cancer

Additional Keywords : Increased Bioavailability

[+]

Curcumin alters the phase II distribution of resveratrol through inhibiting efflux transporters including MRP2 and BCRP.Oct 25, 2015

Click here to read the entire abstract

Pubmed Data : Pharm Res. 2015 Oct 26. Epub 2015 Oct 26. PMID: 26502886

Article Published Date : Oct 25, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin, Resveratrol

Additional Keywords : Increased Bioavailability, Metabolites

[+]

Curcumin can prevent the formation of cholesterol gallstones induced by high fat diet in mice.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Lipids Health Dis. 2015 ;14(1):100. Epub 2015 Sep 3. PMID: 26335572

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Substances : Curcumin, Piperine

Diseases : Gallstones, High Fat Diet

Additional Keywords : Increased Bioavailability, Natural Substance Synergy

[+]

Fructooligosaccharides increase in plasma concentration of (-)-epigallocatechin-3-gallate.Dec 05, 2021

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2021 Dec 6. Epub 2021 Dec 6. PMID: 34870993

Article Published Date : Dec 05, 2021

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), FOS (Fructooligosaccharides)

Additional Keywords : Increased Bioavailability

[+]

Ginsenoside holds a promising potential as a pharmaceutical excipient in the pharmaceutical industries to increase the utility of various bioactives.Jun 30, 2017

Click here to read the entire abstract

Pubmed Data : Arch Pharm Res. 2017 Jul ;40(7):864-874. Epub 2017 Jul 15. PMID: 28712035

Article Published Date : Jun 30, 2017

Study Type : Animal Study

Additional Links

Substances : Curcumin, Ginsenosides

Additional Keywords : Increased Bioavailability

[+]

Oral administration of Curcuma longa associated with white pepper at doses that can be extrapolated to human exposure upon supplementation improves pro-inflammatory disorders.Dec 31, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2013 ;8(11):e81252. Epub 2013 Nov 19. PMID: 24260564

Article Published Date : Dec 31, 2012

Study Type : Animal Study

Additional Links

Substances : Curcumin, Piperine, White Pepper

Diseases : High Fat Diet, Inflammation, Obesity

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor

Additional Keywords : Dietary Concentrations, Increased Bioavailability, Plant Extracts

[+]

Piperine enhanced the bioavailability of curcumin and potentiated its protective effects against CUS induced cognitive impairment and associated oxidative damage in mice.Dec 06, 2012

Click here to read the entire abstract

Pubmed Data : Brain Res. 2012 Dec 7 ;1488:38-50. Epub 2012 Oct 23. PMID: 23099054

Article Published Date : Dec 06, 2012

Study Type : Animal Study

Additional Links

Substances : Curcumin, Piperine

Diseases : Cognitive Decline/Dysfunction, Oxidative Stress, Stress

Pharmacological Actions : Neuroprotective Agents

Additional Keywords : Increased Bioavailability, Natural Substance Synergy

Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

[+]

These studies demonstrate a previously undiscovered mechanism by which glutathione status positively upregulates the bioavailability of vitamin D.Aug 29, 2018

Click here to read the entire abstract

Pubmed Data : Antioxid Redox Signal. 2018 Aug 30. Epub 2018 Aug 30. PMID: 30160165

Article Published Date : Aug 29, 2018

Study Type : Animal Study

Additional Links

Substances : Glutathione, Vitamin D

Diseases : Vitamin D Deficiency

Additional Keywords : Gene Expression Regulation, Increased Bioavailability, Natural Substance Synergy

[+]

This study demonstrated that piperine significantly improved the in vivo bioavailability of emodin.Nov 09, 2015

Click here to read the entire abstract

Pubmed Data : J Pharm Biomed Anal. 2015 Nov 10 ;115:144-9. Epub 2015 Jun 23. PMID: 26201645

Article Published Date : Nov 09, 2015

Study Type : Animal Study

Additional Links

Substances : Emodin, Piperine

Additional Keywords : Increased Bioavailability

[+]

Tinospora cordifolia extract could increase in the bio availability of glibenclamide.Mar 19, 2018

Click here to read the entire abstract

Pubmed Data : J Pharm Biomed Anal. 2018 Mar 20 ;151:310-316. Epub 2018 Jan 10. PMID: 29413979

Article Published Date : Mar 19, 2018

Study Type : Animal Study

Additional Links

Substances : Guduchi

Additional Keywords : Increased Bioavailability, Medication Reduction, Natural Substance/Drug Synergy, Plant Extracts

Problem Substances : Glibenclamide

[+]

Buttermilk Yogurt enhanced the bioaccessibility of curcuminoids.Feb 29, 2016

Click here to read the entire abstract

Pubmed Data : J Food Sci. 2016 Mar ;81(3):H769-76. Epub 2016 Jan 29. PMID: 26824961

Article Published Date : Feb 29, 2016

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, Yoghurt

Additional Keywords : Increased Bioavailability

[+]

Co-encapsulate epigallocatechin-3-gallate and quercetin led to a 2- and 4-fold increase in their effective bio-accessibility.Mar 25, 2018

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2018 Mar 26. Epub 2018 Mar 26. PMID: 29578697

Article Published Date : Mar 25, 2018

Study Type : In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate), Quercetin

Additional Keywords : Increased Bioavailability

[+]

Enhanced oral bioavailability of Tanshinone IIA using lipid nanocapsules.Jul 02, 2020

Click here to read the entire abstract

Pubmed Data : Int J Pharm. 2020 Jul 3 ;586:119598. Epub 2020 Jul 3. PMID: 32629068

Article Published Date : Jul 02, 2020

Study Type : In Vitro Study

Additional Links

Substances : Tanshinone IIA

Additional Keywords : Increased Bioavailability

[+]

Enhanced resorption of liposomal packed vitamin C monitored by ultrasound.May 25, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Clin Med. 2020 May 26 ;9(6). Epub 2020 May 26. PMID: 32466592

Article Published Date : May 25, 2020

Study Type : In Vitro Study

Additional Links

Substances : Vitamin C

Additional Keywords : Increased Bioavailability

[+]

Enhancing curcumin oral bioavailability through nanoformulations.Jul 31, 2019

Click here to read the entire abstract

Pubmed Data : Eur J Drug Metab Pharmacokinet. 2019 Aug ;44(4):459-480. PMID: 30771095

Article Published Date : Jul 31, 2019

Study Type : Review

Additional Links

Substances : Curcumin

Additional Keywords : Increased Bioavailability, Liposomal Curcumin

[+]

In comparison with conventional soxhlet extraction, ultrasonic-assisted extraction exerted higher free radical scavenging capacities.Dec 31, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2016 ;11(4):e0153457. Epub 2016 Apr 27. PMID: 27120053

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Black Raspberry Seed

Diseases : Hydrogen Peroxide Induced Toxicity

Pharmacological Actions : Antioxidants

Additional Keywords : Increased Bioavailability, Plant Extracts, Ultrasonic-assisted Extraction

[+]

Insights into the bioavailability enhancement of curcumin by piperine in pepper.Apr 24, 2016

Click here to read the entire abstract

Pubmed Data : J Phys Chem A. 2016 Apr 25. Epub 2016 Apr 25. PMID: 27111639

Article Published Date : Apr 24, 2016

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, Piperine

Additional Keywords : Increased Bioavailability

[+]

Interactions between natural products and tamoxifen in breast cancer.Dec 31, 2021

Click here to read the entire abstract

Pubmed Data : Front Pharmacol. 2022 ;13:847113. Epub 2022 Jun 2. PMID: 35721162

Article Published Date : Dec 31, 2021

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, EGCG (Epigallocatechin gallate), Kaempferol, Myricetin, Quercetin, Silibinin

Diseases : Breast Cancer

Pharmacological Actions : Chemotherapeutic

Additional Keywords : Increased Bioavailability, Synergy with Tamoxifen

[+]

Lycopene loaded whey protein isolate nanoparticles: An innovative endeavor for enhanced bioavailability of lycopene and anti-cancer activity.Jul 29, 2018

Click here to read the entire abstract

Pubmed Data : Int J Pharm. 2018 Jul 30 ;546(1-2):97-105. Epub 2018 Apr 30. PMID: 29715533

Article Published Date : Jul 29, 2018

Study Type : In Vitro Study

Additional Links

Substances : Lycopene, Whey

Diseases : Breast Cancer

Pharmacological Actions : Antiproliferative

Additional Keywords : Increased Bioavailability

[+]

N-acetylcysteine promotes oral absorption of curcumin.Aug 04, 2020

Click here to read the entire abstract

Pubmed Data : Eur J Pharm Sci. 2020 Aug 5 ;154:105506. Epub 2020 Aug 5. PMID: 32763460

Article Published Date : Aug 04, 2020

Study Type : In Vitro Study

Additional Links

Substances : Curcumin, NAC (N-acetyl-L-cysteine)

Additional Keywords : Increased Bioavailability, Turmeric Absorption

[+]

Targeted Curcumin delivery efficiently regressed cardiac hypertrophy by modulating apoptotic load within cardiac microenvironment.Dec 31, 2015

Click here to read the entire abstract

Pubmed Data : Toxicol Appl Pharmacol. 2016 Jan 1 ;290:54-65. Epub 2015 Nov 21. PMID: 26612707

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Cardiac Hypertrophy

Pharmacological Actions : Anti-Apoptotic, Cardioprotective

Additional Keywords : Increased Bioavailability

[+]

These findings suggested that citric acid could increase the polyphenol content in tea infusions.Sep 09, 2019

Click here to read the entire abstract

Pubmed Data : J Food Biochem. 2019 Sep 10:e13046. Epub 2019 Sep 10. PMID: 31506961

Article Published Date : Sep 09, 2019

Study Type : In Vitro Study

Additional Links

Substances : Black Tea, Citric Acid , Green Tea, Polyphenols, Tea: Oolong, White Tea, Yellow Tea

Pharmacological Actions : Antioxidants

Additional Keywords : Increased Bioavailability

[+]

This study reports that the water solubility of curcumin could be increased 12-fold by the use of heat.Jul 31, 2007

Click here to read the entire abstract

Pubmed Data : Assay Drug Dev Technol. 2007 Aug ;5(4):567-76. PMID: 17767425

Article Published Date : Jul 31, 2007

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Additional Keywords : Increased Bioavailability

[+]

This study suggests a potential therapeutic activity for TEx against human colon cancer, most likely due to the enhanced bioavailability of the turmeric.Jul 31, 2015

Click here to read the entire abstract

Pubmed Data : Altern Ther Health Med. 2015 Aug ;21 Suppl 2:46-54. PMID: 26308760

Article Published Date : Jul 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Turmeric

Diseases : Breast Cancer: Triple Negative , Colon Cancer

Pharmacological Actions : Chemopreventive, Chemotherapeutic

Additional Keywords : Dose Response, Hawaiian Turmeric, Increased Bioavailability, Plant Extracts

[+]

Piperine significantly enhances the bioavailability of EGCG in mice.Aug 01, 2004

Click here to read the entire abstract

Pubmed Data : J Nutr. 2004 Aug;134(8):1948-52.C PMID: 15284381

Article Published Date : Aug 01, 2004

Additional Links

Substances : EGCG (Epigallocatechin gallate), Piperine

Additional Keywords : Increased Bioavailability

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View the Evidence: 33 Abstracts with Increased Bioavailability Research

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Miso soup consumption enhances the bioavailability of the reduced form of supplemental coenzyme Q10.Dec 31, 2019

Supplementation of the diet by exogenous myrosinase via mustard seeds to increase the bioavailability of sulforaphane.Aug 31, 2018

The bioavailability of sulforaphane from glucoraphanin supplements was equal to that from broccoli sprouts.Dec 31, 2014

Transmucosal administration of microgranular curcumin leads to enhanced curcumin bioavailability.Nov 30, 2015

A combination of piperine and ferulic acid might be an alternative therapy in the treatment of psychiatric disorders with high efficacy and low side effects.Jul 29, 2015

Apple cider vinegar induced a protective effect against erythrocyte, kidney, and liver oxidative injury, and lowered the serum lipid levels in mice fed high cholesterol.Jul 31, 2014

Baicalin enhanced oral bioavailability of sorafenib in rats by inducing intestine absorption.Dec 31, 2020

Co-administration of antioxidant significantly increased plasma level of curcumin in animal models.Nov 25, 2015

Colon targeted curcumin microspheres laden with ascorbic acid for bioavailability enhancement.Jul 15, 2018

Curcumin alters the phase II distribution of resveratrol through inhibiting efflux transporters including MRP2 and BCRP.Oct 25, 2015

Curcumin can prevent the formation of cholesterol gallstones induced by high fat diet in mice.Dec 31, 2014

Fructooligosaccharides increase in plasma concentration of (-)-epigallocatechin-3-gallate.Dec 05, 2021

Ginsenoside holds a promising potential as a pharmaceutical excipient in the pharmaceutical industries to increase the utility of various bioactives.Jun 30, 2017

Oral administration of Curcuma longa associated with white pepper at doses that can be extrapolated to human exposure upon supplementation improves pro-inflammatory disorders.Dec 31, 2012

Piperine enhanced the bioavailability of curcumin and potentiated its protective effects against CUS induced cognitive impairment and associated oxidative damage in mice.Dec 06, 2012

These studies demonstrate a previously undiscovered mechanism by which glutathione status positively upregulates the bioavailability of vitamin D.Aug 29, 2018

This study demonstrated that piperine significantly improved the in vivo bioavailability of emodin.Nov 09, 2015

Tinospora cordifolia extract could increase in the bio availability of glibenclamide.Mar 19, 2018

Buttermilk Yogurt enhanced the bioaccessibility of curcuminoids.Feb 29, 2016

Co-encapsulate epigallocatechin-3-gallate and quercetin led to a 2- and 4-fold increase in their effective bio-accessibility.Mar 25, 2018

Enhanced oral bioavailability of Tanshinone IIA using lipid nanocapsules.Jul 02, 2020

Enhanced resorption of liposomal packed vitamin C monitored by ultrasound.May 25, 2020

Enhancing curcumin oral bioavailability through nanoformulations.Jul 31, 2019

In comparison with conventional soxhlet extraction, ultrasonic-assisted extraction exerted higher free radical scavenging capacities.Dec 31, 2015

Insights into the bioavailability enhancement of curcumin by piperine in pepper.Apr 24, 2016

Interactions between natural products and tamoxifen in breast cancer.Dec 31, 2021

Lycopene loaded whey protein isolate nanoparticles: An innovative endeavor for enhanced bioavailability of lycopene and anti-cancer activity.Jul 29, 2018

N-acetylcysteine promotes oral absorption of curcumin.Aug 04, 2020

Targeted Curcumin delivery efficiently regressed cardiac hypertrophy by modulating apoptotic load within cardiac microenvironment.Dec 31, 2015

These findings suggested that citric acid could increase the polyphenol content in tea infusions.Sep 09, 2019

This study reports that the water solubility of curcumin could be increased 12-fold by the use of heat.Jul 31, 2007

This study suggests a potential therapeutic activity for TEx against human colon cancer, most likely due to the enhanced bioavailability of the turmeric.Jul 31, 2015

Piperine significantly enhances the bioavailability of EGCG in mice.Aug 01, 2004

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Increased Bioavailability

View the Evidence:
33 Abstracts with Increased Bioavailability Research