Lectins

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8 Problem Substances Researched for Lectins
NameACCKFocus
Wheat Germ Agglutinin (WGA)2234Locked
Lectins1324Locked
Concanavalin A212Locked
Potato Lectin33Locked
Peanut Oil/ Lectin12Locked
Tomato Lectin22Locked
Gliadin11Locked
Polystyrene nanoparticles11Locked
28 Diseases Researched for Lectins
NameACCKFocus
Thyroid Cancer211Locked
Colorectal Cancer110Locked
Diabetes Mellitus: Type 2110Locked
Inflammation110Locked
Thyroid Neoplasms110Locked
HIV Infections44Locked
Celiac Disease33Locked
Gluten Sensitivity33Locked
Arteriosclerosis12Locked
Brain: Microglial Activation22Locked
Breast Cancer22Locked
Cancers: All12Locked
Colon Cancer12Locked
Demyelinating Diseases12Locked
Gastrointestinal Diseases12Locked
Hepatitis C12Locked
Lectin Associated Toxicity: Tomato22Locked
Low Immune Function: Thymus Dysfunction12Locked
Thymus Atrophy12Locked
Autoimmune Diseases11Locked
Brain Ischemia11Locked
Hepatoma11Locked
Intestinal Permeability 11Locked
Lectin Associated Toxicity11Locked
Lectin-Induced Toxicity11Locked
Oxidative Stress11Locked
Rheumatoid Arthritis11Locked
Thyroid Nodule11Locked
1 Problematic Actions Researched for Lectins
NameACCKFocus
Nanotechnology11Locked
2 Adverse Pharmacological Actions Researched for Lectins
NameACCKFocus
Agglutinizing11Locked
Cytotoxic11Locked
13 Substances Researched for Lectins
NameACCKFocus
Fermented Foods and Beverages212Locked
Wheat Germ212Locked
Vitamin D110Locked
Yoghurt110Locked
Griffithsin12Locked
Moringa oleifera12Locked
Banana11Locked
Curcumin11Locked
N-Acetyl D-Glucosamine11Locked
Okra11Locked
Oyster Mushroom: Golden11Locked
Phaseolus vulgaris11Locked
Soybean: Black 11Locked
14 Pharmacological Actions Researched for Lectins
NameACCKFocus
Anti-Inflammatory Agents110Locked
Hypoglycemic Agents110Locked
Antiviral Agents23Locked
Reverse Transcriptase Inhibitors33Locked
Anticarcinogenic Agents12Locked
Antineoplastic Agents22Locked
Immunomodulatory12Locked
Anti-Apoptotic11Locked
Anti-HIV Agents11Locked
Anti-Tumor11Locked
Antifungal Agents11Locked
Antiproliferative 11Locked
Apoptotic11Locked
Neuroprotective Agents11Locked

View the Evidence:
41 Abstracts with Lectins Research

[+]

Effects of vitamin D-fortified low fat yogurt on glycemic status, anthropometric indexes, inflammation, and bone turnover in diabetic postmenopausal women.Jan 31, 2016

Pubmed Data : Clin Nutr. 2016 Feb ;35(1):67-76. Epub 2015 Mar 5. PMID: 25794439
Article Published Date : Jan 31, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D, Yoghurt
Diseases : Diabetes Mellitus: Type 2, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents
Additional Keywords : Lectins
[+]

Fermented wheat germ has therapeutic value in the treatment of colorectal cancer.Mar 01, 2000

Pubmed Data : Hepatogastroenterology. 2000 Mar-Apr;47(32):393-5. PMID: 10791198
Article Published Date : Mar 01, 2000
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Colorectal Cancer
Additional Keywords : Lectins, Plant Extracts
[+]

Wheat germ agglutinin (WGA) and concanavalin A bind to benign and malignant thyroid nodules.Feb 01, 1989

Pubmed Data : Arch Pathol Lab Med. 1989 Feb;113(2):186-9. PMID: 2916907
Article Published Date : Feb 01, 1989
Study Type : Human Study
Additional Links
Diseases : Thyroid Cancer, Thyroid Neoplasms
Additional Keywords : Lectins
Problem Substances : Concanavalin A, Lectins, Wheat Germ Agglutinin (WGA)
[+]

Griffithsin has antiviral activity against hepatitis C virus. Oct 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Antimicrob Agents Chemother. 2011 Nov ;55(11):5159-67. Epub 2011 Sep 6. PMID: 21896910
Article Published Date : Oct 31, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Griffithsin
Diseases : Hepatitis C
Pharmacological Actions : Antiviral Agents
Additional Keywords : Lectins
[+]

Peanut lectin may contribute to the atherogenicity of peanut oil.Aug 01, 1998

Pubmed Data : Lipids. 1998 Aug;33(8):821-3. PMID: 9727614
Article Published Date : Aug 01, 1998
Study Type : Animal Study
Additional Links
Diseases : Arteriosclerosis
Additional Keywords : Lectins
Problem Substances : Peanut Oil/ Lectin
[+]

Toxicity and antitumor activity of the water-soluble lectin from Moringa oleifera Lam. Seeds (WSMoL) in sarcoma 180.Sep 30, 2023

Pubmed Data : Toxicon. 2023 Oct ;234:107306. Epub 2023 Sep 29. PMID: 37778740
Article Published Date : Sep 30, 2023
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Cancers: All
Pharmacological Actions : Immunomodulatory
Additional Keywords : Lectins, Plant Extracts
[+]

Wheat germ agglutinin (WGA) and concanavalin bind to peripheral nerve fibres such as myelin in an animal model.Jan 01, 1996

Pubmed Data : Histochem J. 1996 Jan;28(1):7-12. PMID: 8866643
Article Published Date : Jan 01, 1996
Study Type : Animal Study
Additional Links
Diseases : Demyelinating Diseases
Additional Keywords : Lectins
Problem Substances : Concanavalin A, Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) exhibits anti-nutritive properties, e.g. hypertrophic growth of the pancreas and thymus atrophy.Jul 01, 1993

Pubmed Data : Br J Nutr. 1993 Jul;70(1):313-21. PMID: 8399111
Article Published Date : Jul 01, 1993
Study Type : Animal Study
Additional Links
Diseases : Low Immune Function: Thymus Dysfunction, Thymus Atrophy
Additional Keywords : Lectins, Lectins As Insecticides
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ extract inhibits experimental colon carcinogenesis.Sep 30, 2001

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Carcinogenesis. 2001 Oct ;22(10):1649-52. PMID: 11577004
Article Published Date : Sep 30, 2001
Study Type : Animal Study
Additional Links
Substances : Fermented Foods and Beverages, Wheat Germ
Diseases : Colon Cancer
Pharmacological Actions : Anticarcinogenic Agents
Additional Keywords : Lectins, Phytotherapy, Plant Extracts
[+]

Wheat lectin may be responsible for contributing to intestinal disease.May 01, 1982

Pubmed Data : Gastroenterology. 1982 May;82(5 Pt 1):838-48. PMID: 6895878
Article Published Date : May 01, 1982
Study Type : Animal Study
Additional Links
Diseases : Gastrointestinal Diseases
Additional Keywords : Lectins
Problem Substances : Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) exhibits activity in a plasma membrane preparation of rat pancreas, which can be blocked by a n-acetyl-d-glucosamine rich glyoprotein.Jun 01, 1977

Pubmed Data : J Cyclic Nucleotide Res. 1977 Jun;3(3):177-87. PMID: 561809
Article Published Date : Jun 01, 1977
Study Type : In Vitro Study
Additional Links
Substances : N-Acetyl D-Glucosamine
Diseases : Gluten Sensitivity, Lectin-Induced Toxicity
Additional Keywords : Lectins
[+]

A lectin purified from black soybeans inhibit HIV-1 reverse transcriptase. Jan 10, 2010

Pubmed Data : Protein Pept Lett. 2010 Jan 10. Epub 2010 Jan 10. PMID: 19715533
Article Published Date : Jan 10, 2010
Study Type : In Vitro Study
Additional Links
Substances : Soybean: Black
Diseases : HIV Infections
Pharmacological Actions : Reverse Transcriptase Inhibitors
Additional Keywords : Lectins
[+]

Banana lectin is a potent inhibitor of HIV replication. Mar 19, 2010

Pubmed Data : J Biol Chem. 2010 Mar 19;285(12):8646-55. Epub 2010 Jan 15. PMID: 20080975
Article Published Date : Mar 19, 2010
Study Type : In Vitro Study
Additional Links
Substances : Banana
Diseases : HIV Infections
Pharmacological Actions : Anti-HIV Agents, Antiviral Agents
Additional Keywords : Lectins, Plant Extracts
[+]

Curcumin protects against cerebral ischemia-induced neuronal cell death.Oct 01, 2005

Pubmed Data : J Neurosci Res. 2005 Oct 1;82(1):138-48. PMID: 16075466
Article Published Date : Oct 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Brain: Microglial Activation, Brain Ischemia, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Additional Keywords : Lectins
[+]

Do dietary lectins cause disease?Apr 16, 1999

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMJ. 1999 Apr 17 ;318(7190):1023-4. PMID: 10205084
Article Published Date : Apr 16, 1999
Study Type : Review
Additional Links
Diseases : Rheumatoid Arthritis
Additional Keywords : Lectins
Problem Substances : Wheat Germ Agglutinin (WGA)
[+]

French bean hemagglutinin exhibits antitumor, antifungal, and anti-HIV-1 reverse transcriptase activities. Sep 07, 2009

Pubmed Data : Phytomedicine. 2009 Sep 7. Epub 2009 Sep 7. PMID: 19740639
Article Published Date : Sep 07, 2009
Study Type : In Vitro Study
Additional Links
Substances : Phaseolus vulgaris
Diseases : Breast Cancer, Hepatoma, HIV Infections
Pharmacological Actions : Anti-Tumor, Antifungal Agents, Reverse Transcriptase Inhibitors
Additional Keywords : Lectins
[+]

Golden Oyster Mushroom (Pleurotos cintrinopileatus) exhibits potent antitumor, mitogenic and HIV reverse transcriptase inhibitory activity. Jan 01, 2008

Pubmed Data : Biochim Biophys Acta. 2008 Jan;1780(1):51-7. Epub 2007 Sep 20. PMID: 17961926
Article Published Date : Jan 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Oyster Mushroom: Golden
Diseases : HIV Infections
Pharmacological Actions : Antineoplastic Agents, Antiproliferative , Reverse Transcriptase Inhibitors
Additional Keywords : Lectins
[+]

Lectin from Okra promotes selective antitumor effects in human breast cancer cells.Feb 28, 2014

Pubmed Data : Biotechnol Lett. 2014 Mar ;36(3):461-9. Epub 2013 Oct 16. PMID: 24129958
Article Published Date : Feb 28, 2014
Study Type : In Vitro Study
Additional Links
Substances : Okra
Diseases : Breast Cancer
Pharmacological Actions : Antineoplastic Agents, Apoptotic
Additional Keywords : Lectins, Selective Cytotoxicity
[+]

Pathologic follicular epithelium (thyroid gland) have an increased expression of WGA receptors, indicating that this lectin may play a role in pathogenesis.Dec 01, 1988

Pubmed Data : Cancer. 1988 Dec 1;62(11):2354-62. PMID: 3179951
Article Published Date : Dec 01, 1988
Study Type : In Vitro Study
Additional Links
Diseases : Thyroid Cancer, Thyroid Nodule
Additional Keywords : Lectins
Problem Substances : Wheat Germ Agglutinin (WGA)
[+]

Potato and wheat lectin share similarities. Nov 01, 1996

Pubmed Data : Int J Biochem Cell Biol. 1996 Nov;28(11):1285-91. PMID: 9022287
Article Published Date : Nov 01, 1996
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Potato Lectin, Wheat Germ Agglutinin (WGA)
[+]

Potato lectin: a modular protein sharing sequence similarities with the extensin family, the hevein lectin family, and snake venom disintegrins (platelet aggregation inhibitors).Jun 01, 1994

Pubmed Data : Plant J. 1994 Jun;5(6):849-61. PMID: 8054990
Article Published Date : Jun 01, 1994
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Potato Lectin
[+]

Review: factors affecting the oral uptake and translocation of polystyrene nanoparticlesJan 01, 1995

Pubmed Data : J Drug Target. 1995 ;3(1):65-70. PMID: 7655823
Article Published Date : Jan 01, 1995
Study Type : Review
Additional Links
Additional Keywords : Lectins
Anti Therapeutic Actions : Nanotechnology
Problem Substances : Polystyrene nanoparticles
[+]

Review: properties of potato lectin and the nature of its glycoprotein linkages.Jun 01, 1978

Pubmed Data : Biochem J. 1978 Jun 1;171(3):665-74. PMID: 666730
Article Published Date : Jun 01, 1978
Study Type : Review
Additional Links
Additional Keywords : Lectins
Problem Substances : Potato Lectin
[+]

The fruit juice of the tomato contains the richest source of agglutinizing activity. Jan 01, 1980

Pubmed Data : Biochem J. 1980 Jan 1;185(1):269-72. PMID: 7378052
Article Published Date : Jan 01, 1980
Study Type : In Vitro Study
Additional Links
Diseases : Lectin Associated Toxicity: Tomato
Additional Keywords : Lectins
Problem Substances : Tomato Lectin
Adverse Pharmacological Actions : Agglutinizing
[+]

Tomato lectin binds selectively to the small intestine epithelium and undergoes uptake through gut associated lymphoid tissue (GALT) and through normal enterocytes.Jun 10, 1999

Pubmed Data : Int J Pharm. 1999 Jun 10;183(1):7-11. PMID: 10361144
Article Published Date : Jun 10, 1999
Study Type : In Vitro Study
Additional Links
Diseases : Intestinal Permeability , Lectin Associated Toxicity, Lectin Associated Toxicity: Tomato
Additional Keywords : Lectins
Problem Substances : Tomato Lectin
[+]

Wheat germ agglutinin (WGA) and concanavalin A can interfere with and/or modulate cellular processes.Sep 01, 1985

Pubmed Data : J Cell Physiol. 1985 Sep;124(3):474-80. PMID: 2995421
Article Published Date : Sep 01, 1985
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) and pertussis toxin are molecularly homologous. Jun 01, 1989

Pubmed Data : Infect Immun. 1989 Jun;57(6):1854-7. PMID: 2722243
Article Published Date : Jun 01, 1989
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins, Molecular Mimicry
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) has fungicidal properties and may function in the defense against fungal pathogens.Mar 01, 1982

Pubmed Data : J Cell Biol. 1982 Mar;92(3):753-64. PMID: 7045136
Article Published Date : Mar 01, 1982
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) has neuromodulatory effects - Article 2. Jan 01, 1993

Pubmed Data : Neuroscience. 1993 Jan;52(1):35-44. PMID: 7679480
Article Published Date : Jan 01, 1993
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) induces antibody anti-WGA formation, which may result in some cross-reactivity to other proteins.Nov 18, 1996

Pubmed Data : FEBS Lett. 1996 Nov 18;397(2-3):139-42. PMID: 8955334
Article Published Date : Nov 18, 1996
Study Type : In Vitro Study
Additional Links
Diseases : Autoimmune Diseases
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) interacts with human platelets as an aggregator and agglutinizer.Dec 01, 1984

Pubmed Data : Thromb Res. 1984 Dec 1;36(5):447-56. PMID: 6441308
Article Published Date : Dec 01, 1984
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) is a very potent platelet stimulator. Oct 30, 2001

Pubmed Data : Biochemistry. 2001 Oct 30;40(43):12992-3001. PMID: 11669637
Article Published Date : Oct 30, 2001
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) is capable of blocking the inhibitory effect of nerve growth factor, in vitro. Feb 01, 1989

Pubmed Data : Cell Struct Funct. 1989 Feb;14(1):87-93. PMID: 2720800
Article Published Date : Feb 01, 1989
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) is capable of modifying nerve growth factor receptor properties.Dec 10, 1983

Pubmed Data : J Biol Chem. 1983 Dec 10;258(23):14136-43. PMID: 6315720
Article Published Date : Dec 10, 1983
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) is cytotoxic toward several tissue culture lines.Sep 05, 1977

Pubmed Data : Biochim Biophys Acta. 1977 Sep 5;469(2):202-10. PMID: 561616
Article Published Date : Sep 05, 1977
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) lectin has neuromodulatory effects. Jul 01, 1999

Pubmed Data : Glia. 1999 Jul;27(1):53-61. PMID: 10401632
Article Published Date : Jul 01, 1999
Study Type : In Vitro Study
Additional Links
Diseases : Brain: Microglial Activation
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin (WGA) may be involved in the pathogenesis of celiac disease.Jan 01, 1986

Pubmed Data : Clin Exp Immunol. 1986 Jan;63(1):95-100. PMID: 3754186
Article Published Date : Jan 01, 1986
Study Type : Commentary
Additional Links
Diseases : Celiac Disease
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat germ agglutinin blocks the biological effects of nerve growth factor.Nov 01, 1985

Pubmed Data : J Cell Biol. 1985 Nov;101(5 Pt 1):1690-4. PMID: 3840487
Article Published Date : Nov 01, 1985
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Lectins, Wheat Germ Agglutinin (WGA)
[+]

Wheat gliadin exhibits non-specific cytotoxicity to a variety of human cells.Feb 14, 1976

Pubmed Data : Lancet. 1976 Feb 14;1(7955):339-41. PMID: 54743
Article Published Date : Feb 14, 1976
Study Type : In Vitro Study
Additional Links
Diseases : Celiac Disease, Gluten Sensitivity
Additional Keywords : Lectins
Problem Substances : Gliadin
Adverse Pharmacological Actions : Cytotoxic
[+]

Wheat lectin may be responsible for aggravating celiac disease through secondary intolerances, as well as the occurence of intestinal lesions in healthy subjects administered high levels of gluten.Dec 01, 1985

Pubmed Data : J Pediatr Gastroenterol Nutr. 1985 Dec;4(6):923-30. PMID: 3906076
Article Published Date : Dec 01, 1985
Study Type : Commentary
Additional Links
Diseases : Celiac Disease, Gluten Sensitivity
Additional Keywords : Lectins
Problem Substances : Wheat Germ Agglutinin (WGA)
[+]

Wheat Lectin: localization within the wheat seed. Sep 15, 1982

Pubmed Data : Biochem J. 1982 Sep 15;206(3):571-6. PMID: 6897353
Article Published Date : Sep 15, 1982
Study Type : In Vitro Study
Additional Links
Additional Keywords : Lectins
Problem Substances : Wheat Germ Agglutinin (WGA)

Lectins Related Articles

Rice, Potato, and Tomato May be as Inflammatory as Wheat
Written by Sayer Ji, Founder
In this article a key question is brought to the forefront, namely, is eating wheat and gluten free enough to obtain optimal health? The mass market has done quite a good job of accommodating the gluten & wheat free movement by providing an increasingly wide number of good tasting and relatively nutritious "whole grain" products. But are whole grains like rice, or other substitute flours like potato, really good for us?
Lectins, Phytates, & Autoimmune Disease: Separating Fact from Fiction
Written by Ali Le Vere, B.S., B.S. - Senior Researcher-GreenMedInfo
Are paleo recommendations to avoid grains and legumes due to anti-nutrient content predicated in science or founded in fear mongering? An evidence-based analysis of the good, the bad, and the ugly when it comes to lectins, phytates, and autoimmune disease

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