Metformin Alternatives

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2 Diseases Researched for Metformin Alternatives
NameACCKFocus
Diabetes Mellitus: Type 2415Locked
Diabetes Mellitus: Type 135Locked
7 Substances Researched for Metformin Alternatives
NameACCKFocus
Berberine212Locked
Chinese Skullcap 12Locked
Cinnamaldehyde12Locked
Cinnamon12Locked
Grapefruit Seed Extract12Locked
Sage12Locked
Curcumin11Locked
2 Pharmacological Actions Researched for Metformin Alternatives
NameACCKFocus
Gluconeogenesis Inhibitor23Locked
AMP-activated protein kinase modulation 11Locked

View the Evidence:
6 Abstracts with Metformin Alternatives Research

[+]

Berberine is a potent oral hypoglycemic agent with benefical effects on lipid metabolism, comparable in efficacy to metformin. May 01, 2008

Pubmed Data : Metabolism. 2008 May;57(5):712-7. PMID: 18442638
Article Published Date : May 01, 2008
Study Type : Human Study
Additional Links
Substances : Berberine
Diseases : Diabetes Mellitus: Type 2
Additional Keywords : Drug: Metformin, Metformin Alternatives, Natural Substances Versus Drugs
[+]

Cinnamaldehyde and berberine have greater anti-diabetic efficacy than metformin. Nov 05, 2008

Pubmed Data : Chin Med J (Engl). 2008 Nov 5;121(21):2124-8. PMID: 19080170
Article Published Date : Nov 05, 2008
Study Type : Animal Study
Additional Links
Substances : Berberine, Cinnamaldehyde, Cinnamon
Diseases : Diabetes Mellitus: Type 2
Additional Keywords : Drug: Metformin, Metformin Alternatives, Superiority of Natural Substances versus Drugs
[+]

Grapefruit seed extract is comparable to metformin in positively modulating blood lipid profiles and blood sugar. Oct 01, 2008

Pubmed Data : Nig Q J Hosp Med. 2008 Oct-Dec;18(4):211-5. PMID: 19391322
Article Published Date : Oct 01, 2008
Study Type : Animal Study
Additional Links
Substances : Grapefruit Seed Extract
Diseases : Diabetes Mellitus: Type 1
Additional Keywords : Drug: Metformin, Metformin Alternatives, Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs
[+]

Sage leaf extract may be an effective treatment for type 2 diabetes.Aug 01, 2006

Pubmed Data : Br J Nutr. 2006 Aug;96(2):326-33. PMID: 16923227
Article Published Date : Aug 01, 2006
Study Type : Animal Study
Additional Links
Substances : Sage
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Gluconeogenesis Inhibitor
Additional Keywords : Drug: Metformin, Metformin Alternatives
[+]

Scutellaria baicalensis (skullcap) enhances the anti-diabetic activity of metformin in diabetic rats. Jan 01, 2008

Pubmed Data : Am J Chin Med. 2008;36(3):517-40. PMID: 18543386
Article Published Date : Jan 01, 2008
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Diabetes Mellitus: Type 1
Additional Keywords : Drug: Metformin, Drug-Plant-Vitamin Synergies, Metformin Alternatives
[+]

Curcumin's blood sugar lowering effect may be due to its inhibitory effect on hepatic gluconeogenesis. Oct 16, 2009

Pubmed Data : Biochem Biophys Res Commun. 2009 Oct 16;388(2):377-82. Epub 2009 Aug 8. PMID: 19665995
Article Published Date : Oct 16, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2
Pharmacological Actions : AMP-activated protein kinase modulation , Gluconeogenesis Inhibitor
Additional Keywords : Metformin Alternatives, Natural Substances Versus Drugs

Metformin Alternatives Related Articles

Grape Seed Extract Superior to Blockbuster Diabetes Drug, Preclinical Study Finds
Written by Sayer Ji, Founder
An extract of grape seeds was recently compared to the best-selling diabetes drug Metformin and was found to be superior in correcting adverse physiological responses induced by a high-fat, high-fructose diet

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