Mitochondrial Biogenesis

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15 Diseases Researched for Mitochondrial Biogenesis

Name	AC	CK
Mitochondrial Dysfunction	5	9
Down Syndrome	1	5
Aging	2	4
Mitochondrial Diseases	2	4
Athletic Performance	1	2
Brain Ischemia	1	2
Cardiomegaly	1	2
Diabetes: Eye Disease	1	2
Diabetic Retinopathy	1	2
Hypertension	1	2
Neurodegenerative Diseases	1	2
Retinal Diseases	1	2
Stroke: Ischemic	1	2
Stroke: Recovery	1	2
Obesity	1	1

11 Substances Researched for Mitochondrial Biogenesis

Name	AC	CK
EGCG (Epigallocatechin gallate)	1	5
Sulforaphane	2	3
Acai	1	2
Curcumin	1	2
DMSO (Dimethyl sulphoxide)	1	2
Goji	1	2
Grape	1	2
Polyphenols	1	2
Quercetin	1	2
Resveratrol	1	2
Arginine	1	1

2 Therapeutic Actions Researched for Mitochondrial Biogenesis

Name	AC	CK	Focus
Exercise	6	11
Exercise: Endurance	1	2

6 Pharmacological Actions Researched for Mitochondrial Biogenesis

Name	AC	CK
Lipolytic	1	2
Nrf2 activation	1	2
Peroxisome Proliferators	1	2
Antioxidant Effects	1	1
Glucose Uptake Optimization	1	1
Phase II Detoxification Enzyme Inducer	1	1

Research Articles 16
Cumulative Knowledge Score 25
Overall Research Rating GOOD

View the Evidence:
16 Abstracts with Mitochondrial Biogenesis Research

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Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome.Jan 01, 2013

Click here to read the entire abstract

Pubmed Data : Biochim Biophys Acta. 2013 Jan 2. Epub 2013 Jan 2. PMID: 23291000

Article Published Date : Jan 01, 2013

Study Type : Human In Vitro

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Down Syndrome

Additional Keywords : Mitochondrial Biogenesis

[+]

"A botanical containing freeze dried açai pulp promotes healthy aging and reduces oxidative damage in sod1 knockdown flies."May 26, 2012

Click here to read the entire abstract

Pubmed Data : Age (Dordr). 2012 May 26. Epub 2012 May 26. PMID: 22639178

Article Published Date : May 26, 2012

Study Type : Insect Study

Additional Links

Substances : Acai

Diseases : Aging

Additional Keywords : Mitochondrial Biogenesis

[+]

"Polyphenols decreased liver NADPH oxidase activity, increased muscle mitochondrial biogenesis and decreased gastrocnemius age-dependent autophagy in aged rats."May 18, 2012

Click here to read the entire abstract

Pubmed Data : Free Radic Res. 2012 May 18. Epub 2012 May 18. PMID: 22607117

Article Published Date : May 18, 2012

Study Type : Animal Study

Additional Links

Substances : Grape, Polyphenols

Additional Keywords : Mitochondrial Biogenesis

[+]

Curcumin treatment enhances the effect of exercise on mitochondrial biogenesis in skeletal muscles.Sep 30, 2015

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Pubmed Data : Metabolism. 2015 Oct ;64(10):1334-47. Epub 2015 Jul 21. PMID: 26278015

Article Published Date : Sep 30, 2015

Study Type : Animal Study

Additional Links

Substances : Curcumin, DMSO (Dimethyl sulphoxide)

Therapeutic Actions : Exercise: Endurance

Additional Keywords : Gene Expression, Mitochondrial Biogenesis

[+]

Dietary wolfberry upregulates carotenoid metabolic genes and enhances mitochondrial biogenesis in the retina of db/db diabetic mice.Mar 14, 2013

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Pubmed Data : Mol Nutr Food Res. 2013 Mar 15. Epub 2013 Mar 15. PMID: 23505020

Article Published Date : Mar 14, 2013

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Diabetes: Eye Disease, Diabetic Retinopathy, Retinal Diseases

Additional Keywords : Mitochondrial Biogenesis

[+]

Exercise induces mitochondrial biogenesis after brain ischemia in rats.Jan 08, 2012

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Pubmed Data : Neuroscience. 2012 Jan 8. Epub 2012 Jan 8. PMID: 22266265

Article Published Date : Jan 08, 2012

Study Type : Animal Study

Additional Links

Diseases : Brain Ischemia, Stroke: Ischemic, Stroke: Recovery

Therapeutic Actions : Exercise

Additional Keywords : Mitochondrial Biogenesis

[+]

Exercise training can help minimize detrimental skeletal muscle aging deficits by improving mitochondrial protein quality control and biogenesis.May 09, 2012

Click here to read the entire abstract

Pubmed Data : Am J Physiol Regul Integr Comp Physiol. 2012 May 9. Epub 2012 May 9. PMID: 22573103

Article Published Date : May 09, 2012

Study Type : Animal Study

Additional Links

Diseases : Aging, Mitochondrial Dysfunction

Therapeutic Actions : Exercise

Additional Keywords : Mitochondrial Biogenesis

[+]

Exercise training increases mitochondrial biogenesis in the brain.Aug 04, 2011

Click here to read the entire abstract

Pubmed Data : J Appl Physiol. 2011 Aug 4. Epub 2011 Aug 4. PMID: 21817111

Article Published Date : Aug 04, 2011

Study Type : Animal Study

Additional Links

Diseases : Mitochondrial Dysfunction , Neurodegenerative Diseases

Therapeutic Actions : Exercise

Additional Keywords : Mitochondrial Biogenesis

[+]

Maternal exercise during pregnancy affects mitochondrial enzymatic activity and biogenesis in offspring brain.Dec 10, 2012

Click here to read the entire abstract

Pubmed Data : Int J Neurosci. 2012 Dec 11. Epub 2012 Dec 11. PMID: 23227820

Article Published Date : Dec 10, 2012

Study Type : Animal Study

Additional Links

Diseases : Mitochondrial Diseases

Therapeutic Actions : Exercise

Additional Keywords : Mitochondrial Biogenesis, Transgenerational Epigenetic Modification

[+]

Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance.Apr 01, 2009

Click here to read the entire abstract

Pubmed Data : Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R1071-7. Epub 2009 Feb 11. PMID: 19211721

Article Published Date : Apr 01, 2009

Study Type : Animal Study

Additional Links

Substances : Quercetin

Diseases : Athletic Performance, Mitochondrial Diseases

Therapeutic Actions : Exercise

Additional Keywords : Mitochondrial Biogenesis

[+]

Resveratrol may have a beneficial effect on Ang II-induced cardiac remodeling.Jun 01, 2010

Click here to read the entire abstract

Pubmed Data : Blood Press. 2010 Jun;19(3):196-205. PMID: 20429690

Article Published Date : Jun 01, 2010

Study Type : Animal Study

Additional Links

Substances : Resveratrol

Diseases : Cardiomegaly, Hypertension, Mitochondrial Dysfunction

Additional Keywords : Mitochondrial Biogenesis, Stilbenes

[+]

Sulforaphane enhances lipid metabolism through improved mitochondrial function by Nrf-2 and PGC-1a-dependent mechanisms.Jan 01, 2019

Click here to read the entire abstract

Pubmed Data : Mol Nutr Food Res. 2019 02 ;63(4):e1800795. Epub 2019 Jan 11. PMID: 30578708

Article Published Date : Jan 01, 2019

Study Type : Animal Study

Additional Links

Substances : Sulforaphane

Diseases : Mitochondrial Dysfunction

Pharmacological Actions : Lipolytic, Nrf2 activation, Peroxisome Proliferators

Additional Keywords : Mitochondria, mitochondria dysfunction, Mitochondrial Biogenesis

[+]

"The axonal transport of mitochondria."May 22, 2012

Click here to read the entire abstract

Pubmed Data : J Cell Sci. 2012 May 22. Epub 2012 May 22. PMID: 22619228

Article Published Date : May 22, 2012

Study Type : Review

Additional Links

Additional Keywords : Mitochondria, Mitochondrial Biogenesis

[+]

Exercise causes an increase in systemic mitochondrial biogenesis. Sep 02, 2011

Click here to read the entire abstract

Pubmed Data : Appl Physiol Nutr Metab. 2011 Sep 2. Epub 2011 Sep 2. PMID: 21888528

Article Published Date : Sep 02, 2011

Study Type : Review

Additional Links

Diseases : Mitochondrial Dysfunction

Therapeutic Actions : Exercise

Additional Keywords : Mitochondrial Biogenesis

[+]

L-arginine has a potential benefit in reducing obesity. Jul 01, 2010

Click here to read the entire abstract

Pubmed Data : Amino Acids. 2010 Jul;39(2):349-57. Epub 2010 May 1. PMID: 20437186

Article Published Date : Jul 01, 2010

Study Type : Review

Additional Links

Substances : Arginine

Diseases : Obesity

Additional Keywords : Mitochondrial Biogenesis

[+]

This study elucidates the mechanisms behind the neurovascular protective effects of sulforaphane.Aug 23, 2018

Click here to read the entire abstract

Pubmed Data : Sci Rep. 2018 Aug 23 ;8(1):12708. Epub 2018 Aug 23. PMID: 30139948

Article Published Date : Aug 23, 2018

Study Type : In Vitro Study

Additional Links

Substances : Sulforaphane

Pharmacological Actions : Antioxidant Effects, Glucose Uptake Optimization, Phase II Detoxification Enzyme Inducer

Additional Keywords : Broccoli, Broccoli Sprouts, Cruciferous Vegetables, Drug Metabolism, Mitochondria, Mitochondrial Biogenesis

Mitochondrial Biogenesis Related Articles

Exercise Stops The Mitochondrial Aging Process In Its Tracks

Written by Sayer Ji, Founder

As we age, mitochondrial density (the number of mitochondria per cell), and mitochondrial quality (its genetic and structural integrity) decline. This is largely due to stress, environmental radiation and chemical exposures, prescribed drugs, nutritional deficiencies, imbalances and/or incompatibilities, and mitochondrial DNA defects inherited maternally, but is also a natural part of getting older.

Groundbreaking Discovery: Animal Cells Powered by Sunlight/Chlorophyll

Written by Sayer Ji, Founder

A groundbreaking study published in the Journal of Cell Science reveals an entirely new reason why it is essential that we all 'eat our greens,' as mother always said, namely: it enables your body's mitochondria to produce more ATP energy when exposed to Sunlight.

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 16 Abstracts with Mitochondrial Biogenesis Research

Limited to Members Only

Currently Available Sorting Options

Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome.Jan 01, 2013

"A botanical containing freeze dried açai pulp promotes healthy aging and reduces oxidative damage in sod1 knockdown flies."May 26, 2012

"Polyphenols decreased liver NADPH oxidase activity, increased muscle mitochondrial biogenesis and decreased gastrocnemius age-dependent autophagy in aged rats."May 18, 2012

Curcumin treatment enhances the effect of exercise on mitochondrial biogenesis in skeletal muscles.Sep 30, 2015

Dietary wolfberry upregulates carotenoid metabolic genes and enhances mitochondrial biogenesis in the retina of db/db diabetic mice.Mar 14, 2013

Exercise induces mitochondrial biogenesis after brain ischemia in rats.Jan 08, 2012

Exercise training can help minimize detrimental skeletal muscle aging deficits by improving mitochondrial protein quality control and biogenesis.May 09, 2012

Exercise training increases mitochondrial biogenesis in the brain.Aug 04, 2011

Maternal exercise during pregnancy affects mitochondrial enzymatic activity and biogenesis in offspring brain.Dec 10, 2012

Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance.Apr 01, 2009

Resveratrol may have a beneficial effect on Ang II-induced cardiac remodeling.Jun 01, 2010

Sulforaphane enhances lipid metabolism through improved mitochondrial function by Nrf-2 and PGC-1a-dependent mechanisms.Jan 01, 2019

"The axonal transport of mitochondria."May 22, 2012

Exercise causes an increase in systemic mitochondrial biogenesis. Sep 02, 2011

L-arginine has a potential benefit in reducing obesity. Jul 01, 2010

This study elucidates the mechanisms behind the neurovascular protective effects of sulforaphane.Aug 23, 2018

Mitochondrial Biogenesis Related Articles

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Mitochondrial Biogenesis

View the Evidence:
16 Abstracts with Mitochondrial Biogenesis Research