Natural Substances Versus Drugs

Name	AC	CK
Fluoxetine (trade name Prozac)	14	110
Mefenamic acid	5	50
Chlorhexidine gluconate	4	40
Diclofenac	5	34
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	5	28
Antibiotics	4	22
Ibuprofen	3	22
Statin Drugs	4	15
Simvastatin	2	12
Oseltamivir (trade name Tamiflu)	2	11
Acetaminophen	1	10
Gemfibrozil	1	10
Hydroxychloroquine sulfate	1	10
Memantine	1	10
Sertraline	1	10
Sodium Fluoride	1	10
Zanamivir	1	10
Indomethacin	2	4
Aspirin	2	3
Allopurinol	1	2
Atorvastatin	1	2
Benzene	1	2
Carrageenan	1	2
Cisplatin	2	2
Corticosteroid	1	2
Donepezil (trade name Aricept)	1	2
Methotrexate	1	2
Pioglitazone (trade Name Actos)	1	2
Rosiglitazone (trade name Avandia)	1	2
Uranium	1	2
Benzodiazepines	1	1
Prednisolone	1	1
Tamoxifen	1	1

Name	AC	CK
Depression	35	266
Osteoarthritis: Knee	14	151
Dental Plaque	15	141
Gingivitis	13	121
Osteoarthritis	12	95
Dysmenorrhea	9	90
Diabetes Mellitus: Type 2	22	80
Inflammation	31	76
Prostatic Hyperplasia: Benign	7	71
Alzheimer's Disease	12	53
Oxidative Stress	18	53
Steptococcus Mutans Infections	7	52
Hyperlipidemia	11	45
Dementia	5	44
Depressive Disorder	5	42
Dyspepsia	4	40
Obsessive-Compulsive Disorder	4	40
Urinary Tract Infections	4	40
Helicobacter Pylori Infection	8	38
Dental Caries	4	35
Pain	10	35
Allergic Rhinitis	5	34
Anxiety Disorders	4	34
Periodontal Diseases	6	33
Chronic Pain	3	32
Generalized Anxiety Disorder	2	30
Mastalgia	2	30
Menopausal Syndrome	4	30
Breast Cancer	13	29
Dyslipidemias	6	27
Hyperglycemia	15	27
Osteoporosis	5	26
Anxiety	5	25
Hypertension	4	24
Influenza	6	24
Depression	3	22
Gastric Ulcer	11	22
Insomnia	3	22
Acne	3	21
Periodontitis	3	21
Atrophic Vaginitis (Vaginal Atrophy)	2	20
Attention Deficit Disorder with Hyperactivity	2	20
Attention Deficit Hyperactivity Disorder	2	20
Candidiasis: Vulvovaginal	2	20
Clotting	2	20
Ear Infection	2	20
Epiphora	1	20
Head Lice	2	20
Hot Flash	2	20
Migraines	2	20
Otitis media	2	20
Postoperative Recovery	2	20
Radiation Induced Illness: Mucositis	2	20
Arthritis	10	19
Candida Albicans	8	18
Rheumatoid Arthritis	5	18
Liver Cancer	9	17
High Cholesterol	4	16
Staphylococcus aureus infection	6	16
Hypercholesterolemia	4	15
Obesity	4	15
Endothelial Dysfunction	3	14
Osteopenia	3	14
Thrombosis	3	14
Cardiovascular Diseases	4	13
Influenza A	4	13
Insulin Resistance	7	13
Arteriosclerosis	2	12
Bronchial Asthma	2	12
Bronchospasm: Acute	2	12
Depression: Postpartum	2	12
Diabetic Nephropathy	2	12
Gastroesophageal Reflux	2	12
Glaucoma	2	12
Gram-Negative Bacterial Infections	2	12
H1N1 Infection	3	12
Ocular Hypertension	2	12
Parkinson's Disease	2	12
Postmenopausal Disorders	3	12
Pulmonary Fibrosis	2	12
Uveitis	2	12
Cardiac Mortality	2	11
Clostridium Infections	2	11
Diarrhea	2	11
Fever	2	11
Giardiasis	2	11
Aging Skin	1	10
Alopecia: Androgenic	1	10
Amebiasis	1	10
Ammonia: Elevated	1	10
Aphthous Ulcer	1	10
Apnea	1	10
Bipolar Disorder	1	10
Blood Coagulation Disorders	1	10
Breast: Mammographic Density	1	10
Bronchitis: Acute	1	10
Bronchoconstriction: Exercise-Induced	1	10
Bunion	1	10
C-Reactive Protein	1	10
Carpal Tunnel Syndrome	1	10
Colic	1	10
Colitis: Ulcerative	1	10
Colonic Spasm	1	10
Constipation	1	10
Cramp	1	10
Dental Caries: Children	1	10
Diverticular Disease	1	10
Diverticulitis	1	10
Ecchymosis	1	10
Eczema	1	10
Edema	1	10
Endodontics	1	10
Endoscopy	1	10
Erythema	1	10
Febrile Infections	1	10
Fibromyalgia	1	10
Fungal Infection	1	10
Gallbladder Surgery: Removal	1	10
Genital Warts	1	10
H3N2 Infection	1	10
Halitosis	1	10
Head and Neck Cancer	1	10
Headache: Migraine	1	10
Hepatic Encephalopathy	1	10
Heroin Addiction/Withdrawal	1	10
Herpes Simplex: Labial	1	10
Human Papilloma Virus	1	10
IgA Nephropathy	1	10
Inflammatory Bowel Diseases	1	10
Interstitial Lung Diseases	1	10
Intraocular hypertension	1	10
Liver Cirrhosis	1	10
Melasma	1	10
Menstrual Cramps	1	10
Mucositis	1	10
Nail Fungus	1	10
Oral Lichen Planus	1	10
Pain: Musculoskeletal	1	10
Post-Thrombotic Syndrome	1	10
Postpartum Blood Loss	1	10
Postpartum Hemorrhage	1	10
Pregnancy: Morning Sickness	1	10
Quality of Life: Poor	1	10
Rhinitis	1	10
Scabies	1	10
Septic Shock	1	10
Sexual Dysfunction	1	10
Sinusitis: Acute	1	10
Sleep Disorders	1	10
Sore Throat	1	10
Suicidal Behavior	1	10
Tendinitis	1	10
Tendinopathy	1	10
Tendinosis	1	10
Tinnitus	1	10
Tonsillitis	1	10
Upper Respiratory Tract Symptoms	1	10
Urinary Tract Infections: Children	1	10
Urogenital Symptoms	1	10
Vaginal Dryness	1	10
Vertigo	1	10
Vesicoureteral reflux	1	10
Warts	1	10
Wound Healing: Periodontal	1	10
Wrinkles	1	10
Colorectal Cancer	6	8
Triglycerides: Elevated	5	8
Diabetic Complications	4	7
Melanoma	4	7
Wound Healing	2	7
Alcohol Toxicity	3	6
Asthma	3	6
Cognitive Decline/Dysfunction	3	6
Coronavirus Infection	4	6
High Fat Diet	3	6
Hyperuricemia	3	6
Blastocystis hominis infections	1	5
Cancers: All	4	5
Candidiasis	1	5
Chemotherapy-Induced Toxicity: Cisplatin	3	5
Diabetes Mellitus: Type 1	3	5
Diabetes: Oxidative Stress	3	5
Epilepsy	3	5
Escherichia coli Infections	4	5
Gram-Positive Bacterial Infections	3	5
Hypoglycemia	3	5
Lipopolysaccharide-Induced Toxicity	4	5
Lung Cancer	3	5
Amnesia	2	4
Chemotherapy and Radiation Toxicity	2	4
Gastric Cancer	3	4
Gastroduodenal Ulcer	2	4
High Fructose Diet	2	4
Myocardial Ischemia	2	4
Neuropathic Pain	2	4
Ovarian Cancer	4	4
Spinal Cord Injuries	2	4
Ulcers	2	4
Advanced Glycation End products (AGE)	2	3
Atherosclerosis	2	3
Brain: Oxidative Stress	2	3
Colon Cancer	2	3
Crigler-Najjar syndrome	1	3
Cytomegalovirus Infections	2	3
Enterococcus Infections	3	3
Gout	2	3
HIV Infections	2	3
Hyperbilirubinemia: Hereditary	1	3
Kidney Damage	2	3
Leishmaniasis	2	3
Leukemia	2	3
Oral Cancer	2	3
Pseudomonas aeruginosa	3	3
Rheumatism	2	3
Squamous cell carcinoma	2	3
Staphylococcus epidermidis	2	3
Toxoplasma gondii Infection	2	3
Toxoplasmosis	2	3
Acid Reflux	1	2
Air Pollution Linked Toxicity	1	2
Alcohol Withdrawal	1	2
Allergic Airway Diseases	1	2
Amnesia: Drug-Induced	1	2
Arthritis: Rheumatoid	1	2
Aspirin-Induced Toxicity	1	2
Atopic Dermatitis	1	2
Bacillus subtilis infections	2	2
Brain Inflammation	1	2
Breast Cancer: Triple Negative	2	2
Carcinoma: Non-Small-Cell Lung	1	2
Cardiomyopathy	1	2
Chemically-Induced Liver Damage	1	2
Chronic Kidney Disease (CKD)	1	2
Coccidiosis	1	2
Colitis	1	2
Colon Cancer: Prevention	1	2
Copper Toxicity	1	2
Corneal Diseases	1	2
Coronary Artery Spasm	1	2
DNA damage	2	2
Dandruff	1	2
Depression: Stress Related	1	2
Diabetes: Cognitive Dysfunction	1	2
Diabetes: Gestational	1	2
Diabetes: Glycation/A1C	1	2
Diabetes: Liver Disease	1	2
Diabetic Neuropathy	1	2
Diabetic Ulcer	1	2
Dog Diseases	1	2
Dry Eye Syndromes	1	2
Emesis	1	2
Estrogen Deficiency	1	2
Gastric Ulcers	1	2
Glioblastoma	1	2
Glioma	1	2
HDL: Low	1	2
Herpes Simplex Virus Type 1	2	2
High Sugar Diet	1	2
Hyperalgesia	1	2
Hyperinsulinism	1	2
Hyperthyroidism	2	2
Hypothyroidism	1	2
Incontinence: Urinary	1	2
Inflammation: Neutrophil-Mediated	1	2
Ischemia	1	2
Learning disorders	1	2
Liver Damage	1	2
Lung Injury: Acute	1	2
Lymphoma: Dalton's	1	2
Melanoma: Metastatic	1	2
Memory Disorders	1	2
Metabolic Diseases	1	2
Multiple Sclerosis	1	2
Myeloproliferative Disorders	1	2
Myointimal Hyperplasia	1	2
Neurodegenerative Diseases	1	2
Opiate Addiction/Withdrawal	1	2
Organ Transplantation: Heart	1	2
Osteoporosis: Male	1	2
Pain: General	1	2
Pancreatic Cancer	2	2
Parasitic Diseases	1	2
Parasitic Intestinal Diseases	1	2
Pica Syndrome	1	2
Prostatic Hyperplasia	1	2
Psoriasis	1	2
Pulmonary Hypertension	1	2
Right Ventricular Hypertrophy	1	2
Schistosomiasis	1	2
Schizophrenia	1	2
Sciatica	1	2
Skin Diseases	1	2
Smoking Cessation: Nicotine Addiction	1	2
Staphylococcus aureus: Methicillin-resistant (MRSA)	2	2
Stress	1	2
Stroke	1	2
Substance Withdrawal Syndrome	1	2
Thyroid Diseases	1	2
Traumatic Brain Injury	1	2
Trichinelliasis	1	2
Ulcerative Colitis	1	2
Uranium Poisoning	1	2
Uric Acid Nephropathy	1	2
Vaccination: Coronavirus	1	2
Actinomyces Infections	1	1
Acute lymphoblastic leukemia (ALL)	1	1
Aspergillosis	1	1
Avian Influenza	1	1
Bacterial Infections and Mycoses	1	1
Birth: Labor & Delivery	1	1
Breast Cancer: Estrogen	1	1
Breast Cancer: Metastatic	1	1
Cancers: Drug Resistant	1	1
Candida Glabrata	1	1
Candida Infection	1	1
Cervical Cancer	1	1
Cough	1	1
Diabetes	1	1
Diabetes Mellitus: Type 2: Prevention	1	1
Diabetic Retinopathy	1	1
Epileptic Seizures	1	1
Fibrosis	1	1
Gastric Cancer: Prevention	1	1
Herpes Labialis	1	1
Infection: Antibiotic Resistant	1	1
Kidney Cancer	1	1
Lipid Peroxidation	1	1
Lymphoma	1	1
MRSA	1	1
Osteosarcoma	1	1
Post-Traumatic Stress Disorders (PTSD)	1	1
Prostate Cancer	1	1
Proteus Vulgaris Infections	1	1
Psychiatric Disorder: Conditioned Fear	1	1
Respiratory Syncytial Virus Infections	1	1
Respiratory Tract Infections	1	1
Salmonella Infections	1	1
Sterility	1	1
Thalassemia	1	1
Thyroid Cancer	1	1
Tumors	1	1
Venereal Diseases: Bacterial	1	1
Climacteric	1	0

Name	AC	CK	Focus
Low Dose Ionizing Radiation	1	2

Name	AC	CK
Saffron	13	150
Turmeric	16	122
Curcumin	28	103
Ginkgo biloba	10	95
Ginger	8	82
Homeopathic Medicine: All	9	82
Chamomile	7	66
Aloe Vera	8	54
Fennel	6	47
Nigella sativa (aka Black Seed)	11	46
Triphala	7	45
Saw Palmetto	4	41
Dill	4	40
Probiotics	4	40
St. John's Wort	3	40
Melatonin	7	38
Garlic	7	37
Berberine	7	34
Red Yeast Rice	5	32
Tea Tree	4	31
Arnica	3	30
Hyaluronic Acid	3	30
Lavender: Essential Oil	2	30
Olive	3	30
St. Johns Wort	7	29
Green Tea	5	25
Thyme	5	25
Genistein	4	24
Licorice	4	24
Lavender	4	23
Coconut Oil	3	22
Omega-3 Fatty Acids	3	22
Pomegranate	4	22
Sage	3	22
Almond	3	21
Catechin	3	21
Cinnamon	3	21
Clove	3	21
Evening Primrose Oil	2	21
Fig	3	21
Peppermint	3	21
Breast Milk	1	20
Caffeine	2	20
Calendula	2	20
Kava Kava	1	20
Lactobacillus Brevis	2	20
Milk Thistle	2	20
Mullein	2	20
Psilocybin	2	20
Tryptophan	2	20
Holy Basil	7	18
Oregano	3	17
Anthocyanins	4	15
Bacopa	3	14
Cannabidiol	9	14
Cumin	3	14
Echinacea	3	14
Pumpkin Seeds	3	14
Vitamin C	3	14
Mango	3	13
Policosanol	3	13
Rose	3	13
Bitter Melon	3	12
Cannabis	2	12
Chinese Skullcap	2	12
Flaxseed	2	12
Garcinia kola	2	12
Hibiscus sabdariffa	2	12
Homeopathic Medicine: Ambra grisea	2	12
Horsetail	2	12
Mucuna pruriens (aka Velvet Beans)	2	12
NAC (N-acetyl-L-cysteine)	2	12
Pumpkin Seed Oil/Meal	2	12
Soy	2	12
Valerian	2	12
White Mulberry	2	12
Cannabinoids	2	11
Chokeberry	2	11
Crocin	2	11
Delta-tetrahydrocannabinol (THC)	2	11
Elderberry	2	11
Eucalyptus	2	11
Fish Oil	2	11
Flavonoids	5	11
Guava	2	11
Magnesium	2	11
Vegetables: All	2	11
5-HTP (5-Hydroxytryptophan)	1	10
Amla Fruit	1	10
Apricot Kernel	1	10
Ayahuasca	1	10
Ayurvedic Formulations	1	10
Biochanin A	1	10
Black Cohosh	1	10
Black Pepper	1	10
Boswellia	1	10
Butterbur	1	10
Cabbage	1	10
Cashew	1	10
Castor oil	1	10
Celadrin	1	10
Cetyl Myristoleate	1	10
Chinense Herbal Formula: Jinniu	1	10
Chinese Herbal Formula: Shuang Huang Lian Wan	1	10
Chlorella (Algae)	1	10
Chlorogenic Acid	1	10
Chrysin	5	10
Coenzyme Q10	1	10
Cranberry	1	10
Curry Tree	1	10
EPA (Eicosapentaenoic Acid)	1	10
Ephedra sinica (Ma Huang)	1	10
Fiber	1	10
Folic Acid	1	10
Frankincense	1	10
Ginseng	1	10
Guggul	1	10
Homeopathic Medicine: Anamirta cocculus	1	10
Homeopathic Medicine: Conium maculatum	1	10
Homeopathic Medicine: Petroleum rectificatum	1	10
Homeopathic Medicine: Traumeel	1	10
Hops	1	10
Horseradish	1	10
Iron	1	10
Kanuka Honey	1	10
Lactobacillus paracasei	1	10
Lactobacillus reuteri	1	10
Lemon Balm	1	10
Manuka Honey	1	10
Methionine	1	10
Nasturtium	1	10
Niacin	1	10
Olive leaf extract	1	10
Ornithine	1	10
Peony	1	10
Piperidines	1	10
Psyllium	1	10
Rhodiola (Tibetan Ginseng)	1	10
SAMe (S-adenosylmethionine)	1	10
Saccharomyces Boulardii	1	10
Salt	1	10
Sesame Seed Oil	1	10
Sesame Seeds	1	10
Sesame oil: topical	1	10
Sodium Bicarbonate	1	10
Thai Herbal Formulations	1	10
Thiamine (B-1)	1	10
Traditional Tibetan Medicine: Zhi Byed 11	1	10
Vitamin B-6	1	10
Vitamin E	1	10
Wintergreen	1	10
Thymoquinone	5	9
Moringa oleifera	4	8
Polyphenols	5	8
Safflower	4	8
EGCG (Epigallocatechin gallate)	5	7
Pomegranate Peel	2	7
Purslane	4	7
Quercetin	4	7
Syrian rue	4	7
Banana	3	6
Bee Propolis	3	6
Coconut	3	6
Cucurbitacin B	3	6
Lotus	3	6
Allicin	3	5
Fucoidan	3	5
Guduchi	3	5
Rutin	3	5
Spirulina	3	5
Xanthones	3	5
Apigenin	3	4
Cissus quadrangularis	2	4
Coconut Water	2	4
Cordyceps Militaris	2	4
Dates	2	4
Equol	2	4
Fenugreek	3	4
Garden Cress (Lepidium sativum)	2	4
Henna	2	4
Krill	3	4
Lettuce	2	4
Naringenin	2	4
Palash	2	4
Plantago	2	4
Tanshinone IIA	2	4
Astaxanthin	2	3
Crocetin	2	3
Gotu Kola	2	3
Grapefruit Seed Extract	2	3
Graviola	2	3
Neem	3	3
Nettle	2	3
Nobiletin	2	3
Oyster Mushroom	2	3
Piperine	2	3
Propolis: Bee	2	3
Propolis: Brazillian	3	3
Puerarin	2	3
Tannic Acid	2	3
Vitamin D	2	3
Acai	1	2
Acorus calamus	1	2
Anise	1	2
Arginine	1	2
Arjuna	1	2
Artemisinin	2	2
Artesunate	1	2
Ashwagandha	1	2
Asiatic Acid	1	2
Baccharis dracunculifolia	1	2
Bael	1	2
Bay leaf	1	2
Beet	1	2
Beta-Caryophyllene	1	2
Black Tea	1	2
Carnosol	1	2
Carvacrol	1	2
Chicory	1	2
Cinnamaldehyde	1	2
Coconut Milk	1	2
Coriandrum sativum	1	2
Cucumber	1	2
Fermented Foods and Beverages	1	2
Fisetin	1	2
Fucoidan: topical	1	2
Gac	1	2
Gardenia	1	2
Gingerol	1	2
Goji	1	2
Grape	1	2
Guarana	1	2
Hawthorn	1	2
Hesperidin	1	2
Homeopathic Treatment: Pulsatilla nigricans	1	2
Hydrogen Water	1	2
Isoflavones	1	2
Jujube	1	2
Justicia gendarussa	1	2
Linden (Tilia)	1	2
Lycopene	1	2
Muskmelon	1	2
Mussel: Green-lipped (Perna canaliculus)	1	2
Myrrh	1	2
Noni	1	2
Onion	2	2
P-Coumaric Acid	1	2
Paeoniflorin	1	2
Panax Ginseng	1	2
Panax Notoginseng	1	2
Papaya	1	2
Parsley	1	2
Pineapple	1	2
Plantain	1	2
Potato: Pigmented	1	2
Prebiotics	1	2
Raspberry ketone	1	2
Reishi Mushroom	1	2
Rice	1	2
Rice Bran	1	2
Rosemaric Acid	1	2
Rosemary	1	2
Rosmarinic acid	1	2
Salvia divinorum	1	2
Seaweed: Brown	1	2
Sessile Joyweed	1	2
Shark Cartilage	1	2
Shiitake Mushroom	1	2
Shikonin	1	2
Shilajit	1	2
Silymarin	1	2
Spearmint	1	2
Tart Cherry	1	2
Tongkat Ali	1	2
Toona sinensis	1	2
Tribulus	1	2
Ursolic Acid	1	2
Verbascoside	1	2
Virgin Coconut Oil	1	2
Vitamin B-12	1	2
Vitamin E: Gamma-tocotrienol	1	2
Vitex Agnus	1	2
Vitex negundo	1	2
Water: Deuterium Depleted	1	2
Watermelon	1	2
Wheat Grass	1	2
White Tea	1	2
Wild Lettuce	1	2
phytoestrogens	1	2
Andrographolide	1	1
Astragalus	1	1
Bacillus subtilis	1	1
Blackberry	1	1
Blueberry	1	1
Burdock	1	1
Caffeoylquinic Acids	1	1
Carpolobia lutea	1	1
Cloudberry	1	1
Elecampane	1	1
Evodia ruteacarpa	1	1
Fish	1	1
Fruit: All	1	1
Gallic Acid	1	1
Garcinia Mangostana	1	1
Gold	1	1
Honeydew (melon)	1	1
Honokiol	1	1
Isoliquiritigenin	1	1
Kratom	1	1
Lemongrass: Essential Oil	1	1
Lime	1	1
Maca	1	1
Magnolol	1	1
Mango Seed	1	1
Mangosteen	1	1
Marshmallow Root	1	1
Mosla scabra	1	1
Mung Bean	1	1
Nutmeg	1	1
Phenethyl isothiocyanate	1	1
Proprietary Nutrient Formulas	1	1
Psychedelics:All	1	1
Radix Isatidis	1	1
Raspberry	1	1
Resveratrol	1	1
Rhubarb	1	1
Salicylic acid	1	1
Sea buckthorn	1	1
Strawberry	1	1
Thymol	1	1
Vitexins	1	1
Willow Bark	1	1
Wine	1	1
Zinc	1	1
Blue-Green Algae	1	0

Name	AC	CK
Homeopathic Treatment	5	42
Photobiomodulation	2	15
Acupressure	1	10
Acupuncture	1	10
Light Therapy	1	10
Massage/Therapeutic Touch	1	10
Moxibustion	1	10
Oil Pulling	1	10
Weight Reduction	1	10
Electroacupuncture	1	2
Exercise	1	2

Name	AC	CK
Analgesics	38	272
Anti-Inflammatory Agents	81	269
Antidepressive Agents	32	212
Antimicrobial	23	147
Anti-Bacterial Agents	31	142
Antioxidants	59	134
Hypoglycemic Agents	34	96
Antiproliferative	37	71
Tumor Necrosis Factor (TNF) Alpha Inhibitor	21	69
Hypolipidemic	20	53
Antiviral Agents	15	52
Apoptotic	26	48
Neuroprotective Agents	21	47
Anti-Anxiety Agents	6	44
Antifungal Agents	8	40
Immunomodulatory	9	32
Anti-Ulcer Agents	11	30
Anticholesteremic Agents	8	30
Interleukin-6 Downregulation	9	30
anti-inflammatory	3	30
Prophylactic Agents	3	22
Anti-Platelet	2	20
Platelet Aggregation Inhibitors	2	20
Vasodilator Agents	2	20
Cardioprotective	5	17
Antihypertensive Agents	4	16
Osteoprotective	4	16
Gastroprotective	8	15
Hepatoprotective	8	15
Interleukin-1 beta downregulation	8	15
Malondialdehyde Down-regulation	7	14
NF-kappaB Inhibitor	9	14
Anticarcinogenic Agents	3	13
Antineoplastic Agents	7	13
Anti-Allergic Agents	2	12
Gastrointestinal Agents	2	12
Hypotensive	2	12
Anti-pyretic	2	11
Antiparasitic Agents	5	11
Cyclooxygenase 2 Inhibitors	7	11
Cyclooxygenase Inhibitors	2	11
Interleukin-8 downregulation	2	11
Adrenergic alpha-Antagonists	1	10
Anti-Androgen	1	10
Anti-collagenase	1	10
Antinoceceptive	5	10
Antioxidant	1	10
Cardiovascular Agents	1	10
Cytotoxic	6	10
Dermatologic Agents	1	10
Diuretics	1	10
Enzyme Inhibitors	1	10
Estrogens	1	10
Insulin Down-Regulation	1	10
Postaglandin PGE2 downregulation	1	10
Regenerative	1	10
Sedative effects	1	10
Uterotonic	1	10
Renoprotective	5	9
Superoxide Dismutase Up-regulation	5	9
Chemotherapeutic	5	7
Analgesics: Non-Narcotic	3	6
Angiogenesis Inhibitors	4	6
Anti-metastatic	4	6
Chemopreventive	5	6
Chemoprotective Agents	3	6
Nrf2 activation	3	6
Radioprotective	3	6
Insulin Sensitizers	3	5
Matrix metalloproteinase-9 (MMP-9) inhibitor	3	5
Acetylcholinesterase Inhibitor	2	4
Anti-Apoptotic	2	4
Antipsychotic Agents	2	4
Cell cycle arrest	3	4
Interleukin-10 downregulation	2	4
Leishmanicidal	3	4
Anticonvulsants	2	3
Antiprotozoal Agents	2	3
Calcium Channel Blockers	2	3
Matrix metalloproteinase-2 (MMP-2) inhibitor	2	3
Nitric Oxide Inhibitor	2	3
5-Lipoxygenase Inhibitor	1	2
Adrenergic alpha-Agonists	1	2
Alpha-amylase inhibitor	2	2
Alpha-glucosidase inhibitor	2	2
Anti-Angiogenic	1	2
Anti-Asthmatic Agents	1	2
Anti-Inflammatory Agents: Non-Steroidal	1	2
Anticoagulants	1	2
Antispasmodic	1	2
Anxiolytic	1	2
Brain-derived neurotrophic factor modulator	1	2
Bronchoconstrictor Agents	1	2
Caspase-3 Activation	2	2
Chemosensitizer	2	2
Cholinesterase Inhibitors	1	2
Cyclooxygenase 1 Inhibitor	1	2
Cytoprotective	1	2
Detoxifier	1	2
Heme oxygenase-1 up-regulation	1	2
Hypnotics and Sedatives	1	2
Interferon Gamma Reducer	1	2
Interleukin-10 upregulation	1	2
Interleukin-12 downregulation	1	2
Interleukin-2 upregulation	1	2
Interleukin-4 upregulation	1	2
Lipoxygenase Inhibitors	1	2
Neurogenesis	1	2
Nootropic Agents	1	2
Pancreato Protective Agents	1	2
Proton Pump Inhibitor	1	2
Radiosensitizer	1	2
Schistosomicides	1	2
Tumor Suppressor Protein p53 Upregulation	2	2
Vascular Endothelial Growth Factor A Inhibitor	1	2
Wnt/β-catenin pathway down-regulation	1	2
apoptosis	1	2
AMP-activated protein kinase modulation	1	1
Anti-Glycation Agents	1	1
Anti-HIV Agents	1	1
Antidiarrheals	1	1
Antigiardial agents	1	1
Caspase-8 activation	1	1
Catalase Up-Regulation	1	1
Cyclin D1 Down-Regulation	1	1
Gluconeogenesis Inhibitor	1	1
Heat Shock Protein Down-Regulation	1	1
Histone deacetylase inhibitor	1	1
Insulin-releasing	1	1
Lactate Dehydrogenase A Inhibitor	1	1
MicroRNA modulator	1	1
Neurominidase Inhibitor	1	1
P21 Activation	1	1
Prostaglandin PGE2 downregulation	1	1
Reverse Transcriptase Inhibitors	1	1
SIRT1 Activator	1	1
Telomerase Inhibitor	1	1
Vascular Cell Adhesion Molecule-1 Inhibitor	1	1
Vascular Endothelial Growth Factor Inhibitors	1	1
Viral Hemagglutinin Inhibitor	1	1

[+]

Efficacy of Curcuma longa in relieving pain symptoms of knee osteoarthritis patients.Dec 31, 2024

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Rheum Dis. 2025 Jan 1 ;32(1):17-29. Epub 2024 Nov 6. PMID: 39712249

Article Published Date : Dec 31, 2024

Study Type : Meta Analysis, Review

Additional Links

Substances : Turmeric

Diseases : Osteoarthritis: Knee

Pharmacological Actions : Analgesics

Additional Keywords : Natural Substances Versus Drugs

[+]

A systematic review of the literature showed that Permixon was effective for relieving urinary symptoms due to prostate enlargement.Nov 30, 2016

Click here to read the entire abstract

Pubmed Data : Eur Urol Focus. 2016 Dec ;2(5):553-561. Epub 2016 Apr 23. PMID: 28723522

Article Published Date : Nov 30, 2016

Study Type : Meta Analysis, Review

Additional Links

Substances : Saw Palmetto

Diseases : Prostatic Hyperplasia: Benign

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

Evening primrose oil is a safe medication with similar efficacy for pain control in women with mastalgia to topical NSAIDS, danazol, or vitamin E.Jun 09, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Environ Res Public Health. 2021 Jun 10 ;18(12). Epub 2021 Jun 10. PMID: 34200727

Article Published Date : Jun 09, 2021

Study Type : Meta Analysis, Review

Additional Links

Substances : Evening Primrose Oil

Diseases : Mastalgia

Pharmacological Actions : Analgesics

Additional Keywords : Natural Substances Versus Drugs

[+]

Ginkgo biloba, chamomile and kava kava exhibit therapeutic potential in generalizaed anxiety disorder.Oct 15, 2010

Click here to read the entire abstract

Pubmed Data : Rev Bras Psiquiatr. 2010 Oct 15. Epub 2010 Oct 15. PMID: 20963375

Article Published Date : Oct 15, 2010

Study Type : Meta Analysis

Additional Links

Substances : Chamomile, Ginkgo biloba, Kava Kava

Diseases : Generalized Anxiety Disorder

Additional Keywords : Benzodiazepine Alternatives, Benzodiazepine Receptor Agonist, Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

[+]

Saffron was effective in the treatment of major depressive disorder and had comparable efficacy to synthetic antidepressants.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Neuropsychiatr Dis Treat. 2018 ;14:1297-1305. Epub 2018 May 21. PMID: 29849461

Article Published Date : Dec 31, 2017

Study Type : Meta Analysis

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

The findings of this study showed that saffron administration was well comparable with fluoxetine and placebo.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Psychol Res Behav Manag. 2019 ;12:297-305. Epub 2019 Apr 23. PMID: 31118846

Article Published Date : Dec 31, 2018

Study Type : Meta Analysis, Review

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Fluoxetine (trade name Prozac)

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Clin J Pain. 2009 May;25(4):327-33. PMID: 19590482

Article Published Date : May 01, 2009

Study Type : Human Study

Additional Links

Diseases : Carpal Tunnel Syndrome

Therapeutic Actions : Acupuncture

Additional Keywords : Natural Substances Versus Drugs

[+]

Administration of olive oil followed by a low volume of polyethylene glycol-electrolyte lavage solution improves patient satisfaction with right-side colonic cleansing over conventional preparation. Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : Gastrointest Endosc. 2009 Sep;70(3):515-21. Epub 2009 Jun 24. PMID: 19555936

Article Published Date : Sep 01, 2009

Study Type : Human Study

Additional Links

Substances : Olive

Diseases : Constipation

Additional Keywords : Natural Substances Versus Drugs

[+]

Click here to read the entire abstract

Pubmed Data : Clin Exp Allergy. 2004 Apr;34(4):646-9. PMID: 15080820

Article Published Date : Apr 01, 2004

Study Type : Human Study

Additional Links

Substances : Butterbur

Diseases : Allergic Rhinitis

Additional Keywords : Natural Substances Versus Drugs

[+]

Cabbage leaf application and cooling gel pad application showed similar improvements in reducing osteoarthritis symptoms.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pain Res Manag. 2022 ;2022:3122153. Epub 2022 Jun 8. PMID: 35719197

Pubmed Data : Phytother Res. 1999 Jun;13(4):318-22. PMID: 10404539

Article Published Date : Jun 01, 1999

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Uveitis

Additional Keywords : Cortisone Alternatives, Natural Substances Versus Drugs

[+]

Curcumin is comparable to chlorhexidine as an anti-inflammatory mouthwash. Thus, it can be considered as an effective adjunct to mechanical periodontal therapy.Dec 31, 2012

Click here to read the entire abstract

Pubmed Data : Oral Health Prev Dent. 2013 ;11(1):81-6. PMID: 23507685

Article Published Date : Dec 31, 2012

Study Type : Human Study

Additional Links

Substances : Curcumin

Diseases : Gingivitis, Periodontal Diseases

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Chlorhexidine gluconate

[+]

Curcumin is safe and efficacious in treating major depressive disorder.Jul 05, 2013

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2013 Jul 6. Epub 2013 Jul 6. PMID: 23832433

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Res Med Sci. 2014 Aug ;19(8):758-61. PMID: 25422662

Article Published Date : Jul 31, 2014

Study Type : Human Study

Additional Links

Substances : Dill

Diseases : Hypercholesterolemia, Hyperlipidemia

Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Gemfibrozil

[+]

Dill was as effective as mefenamic acid in reducing the pain severity in primary dysmenorrhea.Mar 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Res Med Sci. 2014 Apr ;19(4):326-30. PMID: 25097605

Article Published Date : Mar 31, 2014

Study Type : Human Study

Additional Links

Substances : Dill

Diseases : Dysmenorrhea

Pharmacological Actions : Analgesics

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Mefenamic acid

[+]

Echinacea/sage is at least as effective as chlorhexidine/lidocaine for treating acute sore throats. Sep 01, 2009

Click here to read the entire abstract

Pubmed Data : Clin Interv Aging. 2014 ;9:451-8. Epub 2014 Mar 20. PMID: 24672232

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicine (Baltimore). 2020 Jul 10 ;99(28):e20373. PMID: 32664057

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Nurs Midwifery Res. 2013 Sep ;18(5):355-9. PMID: 24403936

Article Published Date : Aug 31, 2013

Study Type : Human Study

Additional Links

Substances : Fennel

Diseases : Dysmenorrhea

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Mefenamic acid

[+]

Fennel is safe and effective for treating primary dysmenorrhea. Feb 01, 2003

Click here to read the entire abstract

Pubmed Data : Int J Gynaecol Obstet. 2003 Feb;80(2):153-7. PMID: 12566188

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Clin Pharm. 2018 Oct ;40(5):1335-1341. Epub 2018 Jun 1. PMID: 29855986

Article Published Date : Sep 30, 2018

Study Type : Human Study

Additional Links

Substances : Ginkgo biloba

Diseases : Tinnitus

Pharmacological Actions : Vasodilator Agents

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

Ginkgo is effective in treating pulmonary interstitial fibrosis.Mar 01, 2005

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2005 Mar;25(3):222-4. PMID: 15842142

In this trial cannabis induced a clinical remission in 50% of patients with long standing Crohn's disease with 80% nonresponse or intolerance to anti–TNF-α treatment.Sep 30, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Gastroenterol Hepatol. 2013 Oct ;11(10):1276-1280.e1. Epub 2013 May 4. PMID: 23648372

Mango leaf mouthwash was effective against salivary microbial population, plaque inhibition, and improved gingival health.Feb 28, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Indian J Dent Res. 2017 Mar-Apr;28(2):151-155. PMID: 28611324

Click here to read the entire abstract

Pubmed Data : Prog Neuropsychopharmacol Biol Psychiatry. 2010 Mar 17;34(2):362-365. Epub 2009 Dec 24. PMID: 20035818

Article Published Date : Mar 17, 2010

Study Type : Human Study

Additional Links

Substances : Milk Thistle

Diseases : Obsessive-Compulsive Disorder

Additional Keywords : Drug: Fluoxetine, Natural Substances Versus Drugs

[+]

Mouthwash containing Anacardium occidentale was effective as an antiplaque and antigingivitis agent.Jun 30, 2016

Click here to read the entire abstract

Pubmed Data : Indian J Dent Res. 2016 Jul-Aug;27(4):364-369. PMID: 27723631

Article Published Date : Jun 30, 2016

Study Type : Human Study

Additional Links

Substances : Cashew

Diseases : Dental Plaque, Gingivitis

Pharmacological Actions : Antimicrobial

Additional Keywords : Mouthwash, Natural Substances Versus Drugs

[+]

Moxibustion is as effective as the benzodiazepine derivative Estrazolam for treating insomnia. Jun 01, 2009

Click here to read the entire abstract

Pubmed Data : J Tradit Chin Med. 2009 Jun;29(2):95-6. PMID: 19663092

Article Published Date : Jun 01, 2009

Study Type : Human Study

Additional Links

Diseases : Insomnia

Therapeutic Actions : Moxibustion

Additional Keywords : Natural Substances Versus Drugs

[+]

Mucuna pruriens could be a sustainable alternative to marketed levodopa for indigent individuals with Parkinson disease.Jul 31, 2017

Pubmed Data : Chin Med J (Engl). 2008 Aug 20;121(16):1588-94. PMID: 18982874

Article Published Date : Aug 20, 2008

Study Type : Human Study

Additional Links

Substances : Omega-3 Fatty Acids, Red Yeast Rice

Diseases : Cardiac Mortality , Cardiovascular Diseases

Additional Keywords : Natural Substances Versus Drugs

[+]

Oral fennel (Foeniculum vulgare) drop compares favorably to an NSAID on primary dysmenorrhea.Feb 28, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Published Date : Feb 28, 2013

Study Type : Human Study

Additional Links

Substances : Fennel

Diseases : Dysmenorrhea, Menstrual Cramps

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Mefenamic acid

[+]

Oral fennel (Foeniculum vulgare) drop effect on primary dysmenorrhea: Effectiveness of herbal drug.Feb 28, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Nurs Midwifery Res. 2013 Mar ;18(2):128-32. PMID: 23983742

Article Published Date : Feb 28, 2013

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Intercult Ethnopharmacol. 2014 Jul-Sep;3(3):109-12. Epub 2014 May 25. PMID: 26401357

Article Published Date : Jun 30, 2014

Study Type : Human Study

Additional Links

Substances : Dill

Diseases : Giardiasis

Pharmacological Actions : Antimicrobial

Additional Keywords : Natural Substances Versus Drugs

[+]

Peppermint is at least as effective as the drug simethicone in the treatment of infantile colic.Dec 31, 2011

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2012 ;2012:981352. Epub 2012 Jul 12. PMID: 22844342

Article Published Date : Dec 31, 2011

Study Type : Human Study

Additional Links

Substances : Peppermint

Diseases : Colic

Additional Keywords : Natural Substances Versus Drugs

[+]

Plaintain seeds (psyllium) may be as effective as mesalamine to maintain remission in ulcerative colitis.Feb 01, 1999

Click here to read the entire abstract

Pubmed Data : Am J Gastroenterol. 1999 Feb;94(2):427-33. PMID: 10022641

Article Published Date : Feb 01, 1999

Study Type : Human Study

Additional Links

Substances : Psyllium

Diseases : Colitis: Ulcerative

Additional Keywords : Natural Substances Versus Drugs

[+]

Policosanol (20 mg day) is as effective as aspirin (100 mg day) as a platelet aggregation inhibitor.Oct 01, 1997

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Urol. 2021 Oct 19 ;21(1):147. Epub 2021 Oct 19. PMID: 34666728

Article Published Date : Oct 18, 2021

Study Type : Human Study

Additional Links

Substances : Pumpkin Seeds

Diseases : Prostatic Hyperplasia: Benign

Additional Keywords : Natural Substances Versus Drugs

[+]

Problem Substances : Fluoxetine (trade name Prozac)

[+]

Saffron compares favorably to donepezil in the treatment of mild-to-moderate Alzhemier's disease.Jan 01, 2010

Pubmed Data : Med J Aust. 1990 Oct 15;153(8):455-8. PMID: 2145499

Article Published Date : Oct 15, 1990

Study Type : Human Study

Additional Links

Substances : Tea Tree

Diseases : Acne

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

Thai massage and thai herbal compression provided comparable clinical efficacy to oral ibuprofen after three weeks of treatment.Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Res Int. 2014 ;2014:490512. Epub 2014 Sep 1. PMID: 25254207

Article Published Date : Dec 31, 2013

Study Type : Human Study

Additional Links

Substances : Thai Herbal Formulations

Diseases : Osteoarthritis: Knee

Therapeutic Actions : Acupressure, Massage/Therapeutic Touch

Pharmacological Actions : Analgesics, Anti-Inflammatory Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

The administration of oral maoto granules to healthy adults with seasonal influenza was well tolerated and associated with equivalent clinical and virological efficacy to oseltamivir or zanamivir.Jul 31, 2012

Click here to read the entire abstract

Pubmed Data : J Infect Chemother. 2012 Aug ;18(4):534-43. Epub 2012 Feb 16. PMID: 22350323

Pubmed Data : Am J Drug Alcohol Abuse. 2008;34(6):792-800. PMID: 19016185

Article Published Date : Jan 01, 2008

Study Type : Human Study

Additional Links

Substances : Chinense Herbal Formula: Jinniu

Diseases : Heroin Addiction/Withdrawal

Additional Keywords : Natural Substances Versus Drugs

[+]

The combined formulation of fruit extracts showed excellent antioxidative and anti-collagenase activity as well as a significant effect on anti-wrinkle activity on human skin.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Clin Cosmet Investig Dermatol. 2015 ;8:389-96. Epub 2015 Jul 16. PMID: 26203268

Article Published Date : Dec 31, 2014

Study Type : Human Study, In Vitro Study

Additional Links

Substances : Fig, Ginkgo biloba, Pomegranate, White Mulberry

Diseases : Aging Skin, Wrinkles

Pharmacological Actions : Anti-collagenase, Antioxidants

Additional Keywords : Dose Response, Natural Substances Versus Drugs, Plant Extracts

[+]

The effectiveness of 0.5% C. sinensis extract was more compared to 0.05% sodium fluoride and 0.2% chlorhexidine gluconate mouth rinses.Apr 30, 2015

Click here to read the entire abstract

Pubmed Data : J Int Soc Prev Community Dent. 2015 May-Jun;5(3):218-26. PMID: 26236682

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Evid Based Complement Alternat Med. 2009 Dec ;6(4):507-15. Epub 2007 Oct 25. PMID: 18955261

Article Published Date : Nov 30, 2009

Study Type : Human Study

Additional Links

Substances : Homeopathic Medicine: All

Diseases : Anxiety

Pharmacological Actions : Anti-Anxiety Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

The omega-3 fatty acid EPA is as effective as fluoxetine (Prozac) in treating major depressive disorder. Mar 01, 2008

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMJ Open. 2019 May 14 ;9(5):e026201. Epub 2019 May 14. PMID: 31092654

Article Published Date : May 13, 2019

Study Type : Human Study

Additional Links

Substances : Kanuka Honey

Diseases : Herpes Simplex: Labial

Pharmacological Actions : Antiviral Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

Problem Substances : Diclofenac

[+]

Thymus vulgaris is at least as effective as ibuprofen in reducing the severity of pain and spasm in primary dysmenorrhea.Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

St. Johns Wort extract is a potential alternative to phenobarbital in patients with Crigler-Najjar syndrome type II.Dec 20, 2015

Click here to read the entire abstract

Pubmed Data : Br J Clin Pharmacol. 2015 Dec 21. Epub 2015 Dec 21. PMID: 26692114

Article Published Date : Dec 20, 2015

Study Type : Human: Case Report

Additional Links

Substances : St. Johns Wort

Diseases : Crigler-Najjar syndrome, Hyperbilirubinemia: Hereditary

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

"Tanshinone IIA prevents uric acid nephropathy in rats through NF-κB inhibition."May 31, 2012

Click here to read the entire abstract

Pubmed Data : Planta Med. 2012 Jun ;78(9):866-73. Epub 2012 May 15. PMID: 22588836

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2011 Jan;25(1):128-36. PMID: 20632299

Article Published Date : Jan 01, 2011

Study Type : Animal Study

Additional Links

Substances : Astaxanthin, Ginkgo biloba, Vitamin C

Diseases : Allergic Airway Diseases, Asthma

Pharmacological Actions : Anti-Inflammatory Agents

Additional Keywords : Ibuprofen Alternatives, Natural Substances Versus Drugs, Plant Extracts, Superiority of Natural Substances versus Drugs

[+]

A moringa oleifera extract was shown to be comparable to the standard, 5-Fluorouracil treated animals. Jan 31, 2015

Click here to read the entire abstract

Pubmed Data : Indian J Exp Biol. 2015 Feb ;53(2):98-103. PMID: 25757240

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Pharmacognosy Res. 2011 Oct ;3(4):232-8. PMID: 22224045

Article Published Date : Sep 30, 2011

Study Type : Animal Study

Additional Links

Substances : Banana

Diseases : Ulcers

Pharmacological Actions : Anti-Ulcer Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

Administration of Salvia divinorum extract induced antialgesic effects in both neuropathic and inflammatory pain models.May 10, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Niger J Physiol Sci. 2011 Nov 23 ;26(1):83-8. Epub 2011 Nov 23. PMID: 22314993

Article Published Date : Nov 22, 2011

Study Type : Animal Study

Additional Links

Substances : Banana

Diseases : Diabetic Complications

Pharmacological Actions : Calcium Channel Blockers

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

An extract of turmeric and white mulberry could potentially be considered as a dietary supplement product for the management of arthritis.Mar 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Click here to read the entire abstract

Pubmed Data : Int J Pediatr Otorhinolaryngol. 2016 May ;84:81-7. Epub 2016 Mar 7. PMID: 27063758

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : ACS Med Chem Lett. 2019 Oct 10 ;10(10):1400-1406. Epub 2019 Sep 10. PMID: 31620225

Article Published Date : Oct 09, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Cucurbitacin B

Diseases : Breast Cancer

Pharmacological Actions : Cytotoxic

Additional Keywords : Natural Substances Versus Drugs

[+]

Cucurbitacin B suppresses hyperglycemia associated with a high sugar diet and promotes sleep in Drosophila melanogaster.Feb 27, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mol Cells. 2021 Feb 28 ;44(2):68-78. PMID: 33542166

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Indian J Med Res. 2015 Jun ;141(6):823-32. PMID: 26205026

Article Published Date : May 31, 2015

Study Type : Animal Study

Additional Links

Substances : Turmeric

Diseases : Endothelial Dysfunction, High Fructose Diet, Hyperglycemia, Hyperinsulinism, Hyperlipidemia, Oxidative Stress

Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Natural Substances Versus Drugs

[+]

Curcumin attenuates withdrawal syndrome in a dose dependent manner in comparison with the dependent positive control group.Feb 28, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Ethnopharmacol. 2005 Apr 26;98(3):313-7. PMID: 15814265

Article Published Date : Apr 26, 2005

Study Type : Animal Study

Additional Links

Substances : Dates

Diseases : Gastric Ulcer

Additional Keywords : Natural Substances Versus Drugs, Prevacid (Lansoprazole) Alternatives

[+]

DDW in mice counteracted the behavioral, transcriptional and proliferative changes typical of the depressive-like states, which was comparable to the effects of citalopram.Jan 14, 2015

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Zhen Ci Yan Jiu. 2019 Aug 25 ;44(8):560-5. PMID: 31475488

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Pak Med Assoc. 2015 May ;65(5):519-25. PMID: 26028387

Article Published Date : Apr 30, 2015

Study Type : Animal Study

Additional Links

Substances : Thymoquinone

Diseases : Rheumatoid Arthritis

Pharmacological Actions : Anti-Inflammatory Agents, Nitric Oxide Inhibitor

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Methotrexate

[+]

Evaluation of the antidepressant-like effect of chronic administration of Nigella fixed oil versus fluoxetine.Nov 30, 2021

Click here to read the entire abstract

Pubmed Data : CNS Neurol Disord Drug Targets. 2021 Dec 1. Epub 2021 Dec 1. PMID: 34852753

Article Published Date : Nov 30, 2021

Study Type : Animal Study

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

Extracts of Echinacea were found to have anti-inflammatory and hypoglycaemic activities similar to indomethacin and glibenclamide.Nov 30, 2017

Click here to read the entire abstract

Pubmed Data : Pharm Biol. 2017 Dec ;55(1):649-656. PMID: 27951745

Article Published Date : Nov 30, 2017

Study Type : Animal Study

Additional Links

Substances : Echinacea

Diseases : Hypoglycemia, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypoglycemic Agents

Additional Keywords : Natural Substances Versus Drugs

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View the Evidence: 559 Abstracts with Natural Substances Versus Drugs Research

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Efficacy of Curcuma longa in relieving pain symptoms of knee osteoarthritis patients.Dec 31, 2024

A systematic review of the literature showed that Permixon was effective for relieving urinary symptoms due to prostate enlargement.Nov 30, 2016

Evening primrose oil is a safe medication with similar efficacy for pain control in women with mastalgia to topical NSAIDS, danazol, or vitamin E.Jun 09, 2021

Ginkgo biloba, chamomile and kava kava exhibit therapeutic potential in generalizaed anxiety disorder.Oct 15, 2010

Saffron was effective in the treatment of major depressive disorder and had comparable efficacy to synthetic antidepressants.Dec 31, 2017

The findings of this study showed that saffron administration was well comparable with fluoxetine and placebo.Dec 31, 2018

The results confirm the efficacy of the three herbal active substances in elderly patients with anxiety, depression, and dementia.Jun 19, 2015

Topical mother's milk may provide an effective alternative to topical antibiotics in infant epiphora. Feb 01, 2007

Zingiberaceae extracts are clinically effective hypoalgesic agents and the available data show a better safety profile than non steroidal anti inflammatory drugs.Dec 31, 2014

The intraluminal administration of peppermint oil by using a hand pump is a simple, safe, and convenient alternative to the systemic injection of a cholinergic blocking agent or glucagon during colonoscopy.Feb 01, 2001

2% dill vaginal suppositories were as effective as 100 mg clotrimazole vaginal tablets in reducing both the clinical and microbiological symptoms.Mar 18, 2018

A combination of baicalin (a compound found within Chinese skullcap) and catechin (a polyphenol plant antioxidant) are as effective as naproxen in treating osteoarthritis of the knee. Dec 01, 1985

A combination of garlic, mullein, calendula, st. johns wort and olive oil is as effective as an anesthetic drug for the management of acute otitis media-associated pain. Jul 01, 2001

A combination of nasturtium herb and horseradish root is as effetive in treating acute sinusitis, acute bronchitis and acute urinary tract infections as comparable to treatment with standard antibiotics. Jan 01, 2006

A Comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches.Dec 31, 2021

A diet high in plant sterols, vegetable proteins, viscous fibers and almonds is as effective as the statin drug lovastatin in managing hypercholesterolemia. Jul 23, 2003

A homeopathic combination (Vertigoheel) reduced the frequency, duration, and intensity of vertigo attacks and compared favorably to the drug betahistine hydrochloride. Aug 01, 1998

A homeopathic gel compares favorably to NSAID gel for treating osteoarthritis of the knee.Jul 01, 2000

A homeopathic ointment preparation compares favorably with 1% diclofenac gel for acute symptomatic treatment of tendinopathy.Nov 01, 2005

A horsetail extract produced a diuretic effect that was stronger than that of the negative control and was equivalent to that of hydrochlorothiazide.Dec 31, 2013

A randomized, double-blind, split-face study of topical silymarin vs 2% hydroquinone cream in melasmas.Nov 30, 2022

A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress. Jan 01, 2008

Acupuncture is as effective as low-dose prednisolone for mild-to-moderate carpal tunnel syndrome. May 01, 2009

Administration of olive oil followed by a low volume of polyethylene glycol-electrolyte lavage solution improves patient satisfaction with right-side colonic cleansing over conventional preparation. Sep 01, 2009

Administration of saffron capsules was comparable with memantine in reducing cognitive decline in patients with moderate to severe AD.Jun 30, 2014

Aloe vera and tea tree oil mouthwashes can decrease plaque, gingivitis and S. mutans in the oral cavity in children.May 19, 2019

Aloe vera gel has been shown to be as effective as benzyl benzoate in the treatment of scabies. Mar 09, 2009

Aloe vera may prove an effective mouthwash due to its ability in reducing dental plaque.Mar 31, 2014

Aloe vera mouthwash has comparable antiplaque efficacy as the gold standard 0.2% chlorhexidine gluconate with fewer side effects.Apr 30, 2016

Aloe vera mouthwash was as beneficial as benzydamine mouthwash in alleviating the severity of radiation-induced mucositis.Dec 31, 2014

An extract of saw palmetto compares favorably with the drug tamsulosin in the treatment of benign prostatic hyperplasia. Jun 01, 2002

An herbal extract combination (Biochanin A, Acetyl tetrapeptide-3, and ginseng extracts) versus 3% minoxidil solution for the treatment of androgenetic alopecia.Sep 30, 2020

Arnica is superior to steroids for reducing adverse effects, e.g. bruising, from rhinoplastic surgery. Jul 01, 2007

Arnica montana is efficacious in healing wound associated with Hallux valgus (bunion) surgery. Jan 01, 2008

Berberine is a potent oral hypoglycemic agent with benefical effects on lipid metabolism, comparable in efficacy to metformin. May 01, 2008

Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression.Oct 06, 2009

Bioavailable turmeric extract is as effective as paracetamol in reducing pain and other symptoms of knee osteoarthritis.Jan 29, 2021

Black chokeberry juice lowered the incidence of Urinary tract infections by 55% and a reduction in antibiotics use in patients. May 31, 2014

Black cohosh compares favorably to fluoxetine in the treatment of postmenopausal symptoms.Feb 28, 2007

Black cumin possesses clinical useful anti-H. pylori activity compared to triple therapy.Jul 01, 2010

Both hyaluronic acid vaginal gel and estriol cream can significantly improve the clinical symptoms of vaginal dryness in postmenopausal women, with improvement rate of 84.44% and 89.42%, respectively, after 10 applications, without statistically significaMay 31, 2013

Bright light treatment, both as monotherapy and in combination with fluoxetine, was efficacious and well tolerated in the treatment of adults with nonseasonal Nonseasonal Major Depressive Disorder.Dec 31, 2015

Butterbur is as effective as fexofenadine in attenuating nasal symptoms in patients with perennial allergic rhinitis. Apr 01, 2004

Cabbage leaf application and cooling gel pad application showed similar improvements in reducing osteoarthritis symptoms.Dec 31, 2021

Caffeine compares favorably to amphetamine in reducing the symptoms of treatment-resistant obsessive-compulsive disorder.Nov 01, 2009

Caffeine is as effective as aminophylline, while it is superior to aminophylline regarding its overall safety.Dec 31, 2017

Castor oil is safe and effective in the treatment of patients wtih osteoarthritis. Oct 01, 2009

Celadrin, a proprietary formula containing Cetyl Myristoleate, improves knee function in patients with osteoarthritisAug 01, 2002

Chamomile extract produced a clinically meaningful reduction in generalized anxiety disorder symptoms over 8 weeks.Dec 14, 2016

Chamomile extract reduced biofilm accumulation and gingival bleeding in patients with gingivitis.Dec 31, 2015

Chamomile is as effective as clotrimazole in vulvovaginal candidiasis treatment.Dec 30, 2021

Cinnamon as compared significantly reduces the severity and duration of pain during menstruation, but this effect is less compared to that of Ibuprofen.Mar 31, 2015

Clove is as effective as benzocaine as a topical anesthesic.Nov 01, 2006

Coconut oil gargling is as effective as using chlorhexidine mouthwash for the reduction of S. mutans.Aug 31, 2016

Comparable efficacy of standardized Ayurveda formulation and hydroxychloroquine sulfate (HCQS) in the treatment of rheumatoid arthritis (RA).Jan 31, 2012

Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.Jan 31, 2013

Comparison of the effect of melatonin, dexmedetomidine, and gabapentin on reduction of postoperative pain and anxiety following laminectomy.Oct 14, 2022

Consumption of rose oil soft capsule alleviates cardinal GERD symptoms similar to omeprazole.Apr 30, 2021

Continual intake of a probiotic drink containing Lactobacillus brevis led to a reduction in the incidence of influenza, especially in subjects not inoculated with influenza vaccine.Nov 30, 2014

Cranberry compares favorably to the drug trimethoprim in the prevention of recurrent urinary tract infections in older women, without increasing the risk of antibiotic resistance/super-infection and/or fungal infection. Feb 01, 2009

Crocin is effective in treatment of patients with mild to moderate OCD with possibly fewer adverse effects compared to fluoxetine.Feb 17, 2021

Crocus sativus compares favorably in the treatment of mild to moderate depression. Feb 27, 2005

Curcuma longa Linn can improve dyspeptic symptoms, improve quality of life, and provide satisfaction equivalent to omeprazole.Oct 14, 2021

Curcumin compares favorably with corticosteroid therapy in the management of chronic anterior uveitis.Jun 01, 1999

Curcumin is comparable to chlorhexidine as an anti-inflammatory mouthwash. Thus, it can be considered as an effective adjunct to mechanical periodontal therapy.Dec 31, 2012

Curcumin is safe and efficacious in treating major depressive disorder.Jul 05, 2013

Cyclic antibiotic therapy in combination with fiber for diverticular disease results in very little benefit in comparison to fiber alone.Sep 01, 2010

Dietary flaxseed lignan improves lower urinary tract symptoms in benign prostatic hyperplasia subjects as well as drug therapy. Jan 01, 2007

Dietary soy supplementation constitutes an effective alternative therapy for somatic and urogenital symptoms of the menopause.Nov 01, 2010

Dill might be beneficial for hypercholesterolemic and hypertriglycemic patients.Jul 31, 2014

Dill was as effective as mefenamic acid in reducing the pain severity in primary dysmenorrhea.Mar 31, 2014

Echinacea/sage is at least as effective as chlorhexidine/lidocaine for treating acute sore throats. Sep 01, 2009

Natural Substances Versus Drugs

View the Evidence:
559 Abstracts with Natural Substances Versus Drugs Research