Natural Substances Versus Drugs

Name	AC	CK
Fluoxetine (trade name Prozac)	14	110
Mefenamic acid	5	50
Chlorhexidine gluconate	4	40
Diclofenac	5	34
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)	5	28
Antibiotics	4	22
Ibuprofen	3	22
Statin Drugs	3	13
Simvastatin	2	12
Oseltamivir (trade name Tamiflu)	2	11
Acetaminophen	1	10
Gemfibrozil	1	10
Hydroxychloroquine sulfate	1	10
Memantine	1	10
Sertraline	1	10
Sodium Fluoride	1	10
Zanamivir	1	10
Aspirin	2	3
Allopurinol	1	2
Benzene	1	2
Carrageenan	1	2
Cisplatin	2	2
Corticosteroid	1	2
Donepezil (trade name Aricept)	1	2
Indomethacin	1	2
Methotrexate	1	2
Pioglitazone (trade Name Actos)	1	2
Rosiglitazone (trade name Avandia)	1	2
Benzodiazepines	1	1
Prednisolone	1	1
Tamoxifen	1	1

Name	AC	CK
Depression	32	253
Dental Plaque	12	120
Gingivitis	11	110
Osteoarthritis: Knee	10	100
Osteoarthritis	12	95
Dysmenorrhea	9	90
Inflammation	29	72
Diabetes Mellitus: Type 2	19	58
Prostatic Hyperplasia: Benign	4	50
Alzheimer's Disease	9	48
Oxidative Stress	15	45
Dementia	5	44
Hyperlipidemia	10	43
Depressive Disorder	5	42
Steptococcus Mutans Infections	5	41
Obsessive-Compulsive Disorder	4	40
Helicobacter Pylori Infection	8	38
Dental Caries	4	35
Anxiety Disorders	4	34
Periodontal Diseases	5	32
Chronic Pain	2	30
Dyspepsia	3	30
Generalized Anxiety Disorder	2	30
Menopausal Syndrome	4	30
Urinary Tract Infections	3	30
Breast Cancer	12	28
Anxiety	5	25
Pain	9	25
Allergic Rhinitis	4	24
Hypertension	4	24
Influenza	6	24
Depression	3	22
Hyperglycemia	12	22
Insomnia	3	22
Acne	3	21
Periodontitis	3	21
Attention Deficit Hyperactivity Disorder	2	20
Clotting	2	20
Ear Infection	2	20
Epiphora	1	20
Head Lice	2	20
Hot Flash	2	20
Otitis media	2	20
Radiation Induced Illness: Mucositis	2	20
Arthritis	10	19
Gastric Ulcer	9	18
Rheumatoid Arthritis	5	18
Candida Albicans	6	16
High Cholesterol	4	16
Osteoporosis	4	16
Dyslipidemias	4	15
Hypercholesterolemia	4	15
Endothelial Dysfunction	3	14
Staphylococcus aureus infection	5	14
Thrombosis	3	14
Cardiovascular Diseases	4	13
Influenza A	4	13
Insulin Resistance	7	13
Obesity	3	13
Arteriosclerosis	2	12
Bronchial Asthma	2	12
Bronchospasm: Acute	2	12
Depression: Postpartum	2	12
Diabetic Nephropathy	2	12
Glaucoma	2	12
Gram-Negative Bacterial Infections	2	12
H1N1 Infection	3	12
Liver Cancer	5	12
Ocular Hypertension	2	12
Osteopenia	2	12
Postmenopausal Disorders	3	12
Pulmonary Fibrosis	2	12
Uveitis	2	12
Cardiac Mortality	2	11
Clostridium Infections	2	11
Diarrhea	2	11
Fever	2	11
Giardiasis	2	11
Aging Skin	1	10
Alopecia: Androgenic	1	10
Amebiasis	1	10
Ammonia: Elevated	1	10
Aphthous Ulcer	1	10
Apnea	1	10
Attention Deficit Disorder with Hyperactivity	1	10
Bipolar Disorder	1	10
Blood Coagulation Disorders	1	10
Breast: Mammographic Density	1	10
Bronchitis: Acute	1	10
Bronchoconstriction: Exercise-Induced	1	10
Bunion	1	10
C-Reactive Protein	1	10
Candidiasis: Vulvovaginal	1	10
Carpal Tunnel Syndrome	1	10
Colic	1	10
Colitis: Ulcerative	1	10
Colonic Spasm	1	10
Constipation	1	10
Cramp	1	10
Dental Caries: Children	1	10
Diverticular Disease	1	10
Diverticulitis	1	10
Ecchymosis	1	10
Eczema	1	10
Edema	1	10
Endoscopy	1	10
Erythema	1	10
Febrile Infections	1	10
Fibromyalgia	1	10
Fungal Infection	1	10
Genital Warts	1	10
H3N2 Infection	1	10
Halitosis	1	10
Head and Neck Cancer	1	10
Headache: Migraine	1	10
Hepatic Encephalopathy	1	10
Heroin Addiction/Withdrawal	1	10
Herpes Simplex: Labial	1	10
Human Papilloma Virus	1	10
IgA Nephropathy	1	10
Inflammatory Bowel Diseases	1	10
Interstitial Lung Diseases	1	10
Intraocular hypertension	1	10
Liver Cirrhosis	1	10
Mastalgia	1	10
Menstrual Cramps	1	10
Migraines	1	10
Mucositis	1	10
Nail Fungus	1	10
Pain: Musculoskeletal	1	10
Post-Thrombotic Syndrome	1	10
Postoperative Recovery	1	10
Postpartum Blood Loss	1	10
Postpartum Hemorrhage	1	10
Pregnancy: Morning Sickness	1	10
Quality of Life: Poor	1	10
Rhinitis	1	10
Scabies	1	10
Sinusitis: Acute	1	10
Sore Throat	1	10
Tendinitis	1	10
Tendinopathy	1	10
Tendinosis	1	10
Tonsillitis	1	10
Upper Respiratory Tract Symptoms	1	10
Urinary Tract Infections: Children	1	10
Urogenital Symptoms	1	10
Vaginal Dryness	1	10
Vertigo	1	10
Vesicoureteral reflux	1	10
Warts	1	10
Wrinkles	1	10
Triglycerides: Elevated	5	8
Alcohol Toxicity	3	6
Asthma	3	6
Diabetic Complications	3	6
Hyperuricemia	3	6
Melanoma	3	6
Blastocystis hominis infections	1	5
Candidiasis	1	5
Chemotherapy-Induced Toxicity: Cisplatin	3	5
Diabetes Mellitus: Type 1	3	5
Diabetes: Oxidative Stress	3	5
Epilepsy	3	5
Escherichia coli Infections	4	5
Gram-Positive Bacterial Infections	3	5
Hypoglycemia	3	5
Amnesia	2	4
Chemotherapy and Radiation Toxicity	2	4
Cognitive Decline/Dysfunction	2	4
Colorectal Cancer	4	4
Gastric Cancer	3	4
Gastroduodenal Ulcer	2	4
High Fat Diet	2	4
High Fructose Diet	2	4
Myocardial Ischemia	2	4
Neuropathic Pain	2	4
Ovarian Cancer	4	4
Spinal Cord Injuries	2	4
Ulcers	2	4
Atherosclerosis	2	3
Cancers: All	2	3
Colon Cancer	2	3
Crigler-Najjar syndrome	1	3
Cytomegalovirus Infections	2	3
Enterococcus Infections	3	3
Gout	2	3
HIV Infections	2	3
Hyperbilirubinemia: Hereditary	1	3
Kidney Damage	2	3
Leishmaniasis	2	3
Leukemia	2	3
Lipopolysaccharide-Induced Toxicity	3	3
Pseudomonas aeruginosa	3	3
Rheumatism	2	3
Squamous cell carcinoma	2	3
Toxoplasma gondii Infection	2	3
Toxoplasmosis	2	3
Acid Reflux	1	2
Advanced Glycation End products (AGE)	1	2
Alcohol Withdrawal	1	2
Allergic Airway Diseases	1	2
Amnesia: Drug-Induced	1	2
Arthritis: Rheumatoid	1	2
Aspirin-Induced Toxicity	1	2
Atopic Dermatitis	1	2
Bacillus subtilis infections	2	2
Brain Inflammation	1	2
Brain: Oxidative Stress	1	2
Cardiomyopathy	1	2
Chemically-Induced Liver Damage	1	2
Chronic Kidney Disease (CKD)	1	2
Coccidiosis	1	2
Colitis	1	2
Colon Cancer: Prevention	1	2
Copper Toxicity	1	2
Corneal Diseases	1	2
Coronary Artery Spasm	1	2
Depression: Stress Related	1	2
Diabetes: Gestational	1	2
Diabetes: Glycation/A1C	1	2
Diabetes: Liver Disease	1	2
Diabetic Neuropathy	1	2
Diabetic Ulcer	1	2
Dog Diseases	1	2
Dry Eye Syndromes	1	2
Emesis	1	2
Estrogen Deficiency	1	2
Gastric Ulcers	1	2
Gastroesophageal Reflux	1	2
Glioblastoma	1	2
Glioma	1	2
HDL: Low	1	2
Herpes Simplex Virus Type 1	2	2
High Sugar Diet	1	2
Hyperalgesia	1	2
Hyperinsulinism	1	2
Hyperthyroidism	2	2
Hypothyroidism	1	2
Incontinence: Urinary	1	2
Inflammation: Neutrophil-Mediated	1	2
Ischemia	1	2
Learning disorders	1	2
Liver Damage	1	2
Lung Injury: Acute	1	2
Lymphoma: Dalton's	1	2
Melanoma: Metastatic	1	2
Memory Disorders	1	2
Metabolic Diseases	1	2
Multiple Sclerosis	1	2
Myeloproliferative Disorders	1	2
Myointimal Hyperplasia	1	2
Neurodegenerative Diseases	1	2
Opiate Addiction/Withdrawal	1	2
Oral Cancer	1	2
Organ Transplantation: Heart	1	2
Osteoporosis: Male	1	2
Pain: General	1	2
Parasitic Diseases	1	2
Parasitic Intestinal Diseases	1	2
Parkinson's Disease	1	2
Pica Syndrome	1	2
Pulmonary Hypertension	1	2
Right Ventricular Hypertrophy	1	2
Schistosomiasis	1	2
Schizophrenia	1	2
Sciatica	1	2
Staphylococcus aureus: Methicillin-resistant (MRSA)	2	2
Stress	1	2
Stroke	1	2
Substance Withdrawal Syndrome	1	2
Thyroid Diseases	1	2
Traumatic Brain Injury	1	2
Trichinelliasis	1	2
Ulcerative Colitis	1	2
Uric Acid Nephropathy	1	2
Wound Healing	1	2
Actinomyces Infections	1	1
Acute lymphoblastic leukemia (ALL)	1	1
Aspergillosis	1	1
Avian Influenza	1	1
Bacterial Infections and Mycoses	1	1
Birth: Labor & Delivery	1	1
Breast Cancer: Estrogen	1	1
Breast Cancer: Metastatic	1	1
Breast Cancer: Triple Negative	1	1
Cancers: Drug Resistant	1	1
Candida Glabrata	1	1
Candida Infection	1	1
Cough	1	1
Diabetes	1	1
Diabetes Mellitus: Type 2: Prevention	1	1
Epileptic Seizures	1	1
Fibrosis	1	1
Gastric Cancer: Prevention	1	1
Herpes Labialis	1	1
Infection: Antibiotic Resistant	1	1
Kidney Cancer	1	1
Lung Cancer	1	1
Lymphoma	1	1
MRSA	1	1
Osteosarcoma	1	1
Pancreatic Cancer	1	1
Post-Traumatic Stress Disorders (PTSD)	1	1
Prostate Cancer	1	1
Proteus Vulgaris Infections	1	1
Psychiatric Disorder: Conditioned Fear	1	1
Respiratory Syncytial Virus Infections	1	1
Respiratory Tract Infections	1	1
Salmonella Infections	1	1
Staphylococcus epidermidis	1	1
Sterility	1	1
Thalassemia	1	1
Thyroid Cancer	1	1
Tumors	1	1
Venereal Diseases: Bacterial	1	1
Climacteric	1	0

Name	AC	CK	Focus
Low Dose Ionizing Radiation	1	2

Name	AC	CK
Saffron	12	140
Curcumin	26	100
Turmeric	13	90
Ginkgo biloba	9	85
Homeopathic Medicine: All	9	82
Ginger	7	72
Chamomile	6	56
Aloe Vera	8	54
Fennel	6	47
Dill	4	40
Probiotics	4	40
Saw Palmetto	3	40
St. John's Wort	3	40
Garlic	7	37
Triphala	5	34
Red Yeast Rice	5	32
Tea Tree	4	31
Arnica	3	30
Lavender: Essential Oil	2	30
Nigella sativa (aka Black Seed)	6	30
Olive	3	30
St. Johns Wort	7	29
Green Tea	5	25
Thyme	5	25
Berberine	6	24
Lavender	3	22
Licorice	3	22
Omega-3 Fatty Acids	3	22
Pomegranate	4	22
Sage	3	22
Almond	3	21
Catechin	3	21
Clove	3	21
Fig	3	21
Breast Milk	1	20
Caffeine	2	20
Calendula	2	20
Cinnamon	2	20
Kava Kava	1	20
Lactobacillus Brevis	2	20
Mullein	2	20
Peppermint	2	20
Tryptophan	2	20
Melatonin	5	18
Oregano	3	17
Anthocyanins	4	15
Holy Basil	5	15
Bacopa	3	14
Cumin	3	14
Echinacea	3	14
Genistein	3	14
Policosanol	3	13
Cannabidiol	8	12
Cannabis	2	12
Chinese Skullcap	2	12
Coconut Oil	2	12
Flaxseed	2	12
Homeopathic Medicine: Ambra grisea	2	12
Horsetail	2	12
Mango	2	12
Mucuna pruriens (aka Velvet Beans)	2	12
NAC (N-acetyl-L-cysteine)	2	12
Soy	2	12
Valerian	2	12
White Mulberry	2	12
Cannabinoids	2	11
Chokeberry	2	11
Delta-tetrahydrocannabinol (THC)	2	11
Eucalyptus	2	11
Fish Oil	2	11
Vegetables: All	2	11
5-HTP (5-Hydroxytryptophan)	1	10
Apricot Kernel	1	10
Ayahuasca	1	10
Ayurvedic Formulations	1	10
Biochanin A	1	10
Black Cohosh	1	10
Black Pepper	1	10
Butterbur	1	10
Cashew	1	10
Castor oil	1	10
Celadrin	1	10
Cetyl Myristoleate	1	10
Chinense Herbal Formula: Jinniu	1	10
Chinese Herbal Formula: Shuang Huang Lian Wan	1	10
Chlorella (Algae)	1	10
Chlorogenic Acid	1	10
Chrysin	5	10
Cranberry	1	10
Crocin	1	10
Curry Tree	1	10
EPA (Eicosapentaenoic Acid)	1	10
Ephedra sinica (Ma Huang)	1	10
Fiber	1	10
Garcinia kola	1	10
Ginseng	1	10
Guava	1	10
Guggul	1	10
Homeopathic Medicine: Anamirta cocculus	1	10
Homeopathic Medicine: Conium maculatum	1	10
Homeopathic Medicine: Petroleum rectificatum	1	10
Homeopathic Medicine: Traumeel	1	10
Horseradish	1	10
Hyaluronic Acid	1	10
Iron	1	10
Kanuka Honey	1	10
Lactobacillus paracasei	1	10
Lactobacillus reuteri	1	10
Lemon Balm	1	10
Manuka Honey	1	10
Milk Thistle	1	10
Nasturtium	1	10
Niacin	1	10
Olive leaf extract	1	10
Ornithine	1	10
Peony	1	10
Piperidines	1	10
Psilocybin	1	10
Psyllium	1	10
Rhodiola (Tibetan Ginseng)	1	10
SAMe (S-adenosylmethionine)	1	10
Saccharomyces Boulardii	1	10
Salt	1	10
Sesame Seed Oil	1	10
Sesame Seeds	1	10
Sesame oil: topical	1	10
Sodium Bicarbonate	1	10
Thai Herbal Formulations	1	10
Traditional Tibetan Medicine: Zhi Byed 11	1	10
Vitamin B-6	1	10
Vitamin E	1	10
Wintergreen	1	10
Flavonoids	4	9
Thymoquinone	5	9
Moringa oleifera	4	8
Safflower	4	8
EGCG (Epigallocatechin gallate)	5	7
Polyphenols	4	7
Pomegranate Peel	2	7
Quercetin	4	7
Syrian rue	4	7
Banana	3	6
Bee Propolis	3	6
Coconut	3	6
Lotus	3	6
Allicin	3	5
Purslane	3	5
Rutin	3	5
Xanthones	3	5
Coconut Water	2	4
Cucurbitacin B	2	4
Equol	2	4
Fenugreek	3	4
Henna	2	4
Naringenin	2	4
Palash	2	4
Plantago	2	4
Tanshinone IIA	2	4
Vitamin C	2	4
Astaxanthin	2	3
Fucoidan	2	3
Gotu Kola	2	3
Grapefruit Seed Extract	2	3
Graviola	2	3
Neem	3	3
Nettle	2	3
Nobiletin	2	3
Piperine	2	3
Propolis: Bee	2	3
Puerarin	2	3
Rose	2	3
Spirulina	2	3
Tannic Acid	2	3
Acorus calamus	1	2
Anise	1	2
Apigenin	2	2
Arginine	1	2
Arjuna	1	2
Artemisinin	2	2
Artesunate	1	2
Ashwagandha	1	2
Asiatic Acid	1	2
Baccharis dracunculifolia	1	2
Bael	1	2
Bay leaf	1	2
Beta-Caryophyllene	1	2
Bitter Melon	2	2
Black Tea	1	2
Carnosol	1	2
Carvacrol	1	2
Cinnamaldehyde	1	2
Coconut Milk	1	2
Coriandrum sativum	1	2
Crocetin	1	2
Dates	1	2
Fisetin	1	2
Fucoidan: topical	1	2
Gac	1	2
Gardenia	1	2
Gingerol	1	2
Goji	1	2
Grape	1	2
Guarana	1	2
Guduchi	1	2
Hawthorn	1	2
Hesperidin	1	2
Hibiscus sabdariffa	1	2
Homeopathic Treatment: Pulsatilla nigricans	1	2
Isoflavones	1	2
Justicia gendarussa	1	2
Krill	2	2
Lettuce	1	2
Linden (Tilia)	1	2
Lycopene	1	2
Muskmelon	1	2
Mussel: Green-lipped (Perna canaliculus)	1	2
Myrrh	1	2
Noni	1	2
Onion	2	2
P-Coumaric Acid	1	2
Paeoniflorin	1	2
Panax Ginseng	1	2
Panax Notoginseng	1	2
Papaya	1	2
Parsley	1	2
Pineapple	1	2
Plantain	1	2
Potato: Pigmented	1	2
Prebiotics	1	2
Propolis: Brazillian	2	2
Pumpkin Seed Oil/Meal	1	2
Pumpkin Seeds	1	2
Raspberry ketone	1	2
Reishi Mushroom	1	2
Rice	1	2
Rice Bran	1	2
Rosemary	1	2
Rosmarinic acid	1	2
Salvia divinorum	1	2
Sessile Joyweed	1	2
Shark Cartilage	1	2
Shiitake Mushroom	1	2
Shikonin	1	2
Shilajit	1	2
Silymarin	1	2
Spearmint	1	2
Tart Cherry	1	2
Tongkat Ali	1	2
Toona sinensis	1	2
Tribulus	1	2
Verbascoside	1	2
Virgin Coconut Oil	1	2
Vitamin D	1	2
Vitamin E: Gamma-tocotrienol	1	2
Vitex Agnus	1	2
Vitex negundo	1	2
Water: Deuterium Depleted	1	2
Watermelon	1	2
White Tea	1	2
Wild Lettuce	1	2
phytoestrogens	1	2
Astragalus	1	1
Bacillus subtilis	1	1
Blackberry	1	1
Blueberry	1	1
Burdock	1	1
Caffeoylquinic Acids	1	1
Carpolobia lutea	1	1
Cloudberry	1	1
Elderberry	1	1
Evening Primrose Oil	1	1
Evodia ruteacarpa	1	1
Fish	1	1
Fruit: All	1	1
Gallic Acid	1	1
Garcinia Mangostana	1	1
Gold	1	1
Honeydew (melon)	1	1
Honokiol	1	1
Isoliquiritigenin	1	1
Kratom	1	1
Lemongrass: Essential Oil	1	1
Lime	1	1
Maca	1	1
Magnesium	1	1
Magnolol	1	1
Mango Seed	1	1
Mangosteen	1	1
Marshmallow Root	1	1
Mosla scabra	1	1
Mung Bean	1	1
Oyster Mushroom	1	1
Phenethyl isothiocyanate	1	1
Proprietary Nutrient Formulas	1	1
Radix Isatidis	1	1
Raspberry	1	1
Resveratrol	1	1
Salicylic acid	1	1
Sea buckthorn	1	1
Strawberry	1	1
Thymol	1	1
Vitexins	1	1
Willow Bark	1	1
Wine	1	1
Blue-Green Algae	1	0

Name	AC	CK
Homeopathic Treatment	5	42
Acupressure	1	10
Acupuncture	1	10
Light Therapy	1	10
Massage/Therapeutic Touch	1	10
Moxibustion	1	10
Oil Pulling	1	10
Weight Reduction	1	10
Electroacupuncture	1	2
Exercise	1	2

Name	AC	CK
Anti-Inflammatory Agents	65	220
Antidepressive Agents	29	199
Analgesics	29	169
Antimicrobial	20	134
Anti-Bacterial Agents	28	130
Antioxidants	50	119
Hypoglycemic Agents	28	69
Tumor Necrosis Factor (TNF) Alpha Inhibitor	19	65
Antiproliferative	28	58
Antiviral Agents	14	51
Hypolipidemic	18	49
Anti-Anxiety Agents	6	44
Neuroprotective Agents	17	40
Apoptotic	20	38
Immunomodulatory	8	31
Anticholesteremic Agents	8	30
anti-inflammatory	3	30
Antifungal Agents	6	29
Anti-Ulcer Agents	10	28
Interleukin-6 Downregulation	7	27
Anti-Platelet	2	20
Platelet Aggregation Inhibitors	2	20
Cardioprotective	5	17
Antihypertensive Agents	4	16
Hepatoprotective	8	15
Malondialdehyde Down-regulation	7	14
NF-kappaB Inhibitor	9	14
Antineoplastic Agents	7	13
Hypotensive	2	12
Prophylactic Agents	2	12
Anti-pyretic	2	11
Antiparasitic Agents	5	11
Cyclooxygenase 2 Inhibitors	7	11
Gastroprotective	6	11
Interleukin-1 beta downregulation	6	11
Interleukin-8 downregulation	2	11
Adrenergic alpha-Antagonists	1	10
Anti-Androgen	1	10
Anti-collagenase	1	10
Antinoceceptive	5	10
Cardiovascular Agents	1	10
Cytotoxic	6	10
Dermatologic Agents	1	10
Diuretics	1	10
Enzyme Inhibitors	1	10
Insulin Down-Regulation	1	10
Postaglandin PGE2 downregulation	1	10
Regenerative	1	10
Uterotonic	1	10
Vasodilator Agents	1	10
Superoxide Dismutase Up-regulation	4	8
Chemotherapeutic	5	7
Analgesics: Non-Narcotic	3	6
Anti-metastatic	4	6
Chemopreventive	5	6
Radioprotective	3	6
Renoprotective	3	5
Acetylcholinesterase Inhibitor	2	4
Antipsychotic Agents	2	4
Chemoprotective Agents	2	4
Interleukin-10 downregulation	2	4
Leishmanicidal	3	4
Matrix metalloproteinase-9 (MMP-9) inhibitor	2	4
Nrf2 activation	2	4
Osteoprotective	2	4
Angiogenesis Inhibitors	2	3
Anticarcinogenic Agents	2	3
Anticonvulsants	2	3
Antiprotozoal Agents	2	3
Calcium Channel Blockers	2	3
Cell cycle arrest	2	3
Insulin Sensitizers	2	3
Nitric Oxide Inhibitor	2	3
5-Lipoxygenase Inhibitor	1	2
Adrenergic alpha-Agonists	1	2
Alpha-amylase inhibitor	2	2
Alpha-glucosidase inhibitor	2	2
Anti-Allergic Agents	1	2
Anti-Angiogenic	1	2
Anti-Asthmatic Agents	1	2
Anti-Inflammatory Agents: Non-Steroidal	1	2
Anticoagulants	1	2
Antispasmodic	1	2
Anxiolytic	1	2
Brain-derived neurotrophic factor modulator	1	2
Bronchoconstrictor Agents	1	2
Caspase-3 Activation	2	2
Chemosensitizer	2	2
Cholinesterase Inhibitors	1	2
Cyclooxygenase 1 Inhibitor	1	2
Cytoprotective	1	2
Gastrointestinal Agents	1	2
Heme oxygenase-1 up-regulation	1	2
Interferon Gamma Reducer	1	2
Interleukin-10 upregulation	1	2
Interleukin-12 downregulation	1	2
Interleukin-2 upregulation	1	2
Interleukin-4 upregulation	1	2
Lipoxygenase Inhibitors	1	2
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	2
Nootropic Agents	1	2
Pancreato Protective Agents	1	2
Proton Pump Inhibitor	1	2
Radiosensitizer	1	2
Schistosomicides	1	2
Tumor Suppressor Protein p53 Upregulation	2	2
Vascular Endothelial Growth Factor A Inhibitor	1	2
Wnt/β-catenin pathway down-regulation	1	2
apoptosis	1	2
AMP-activated protein kinase modulation	1	1
Anti-HIV Agents	1	1
Antidiarrheals	1	1
Antigiardial agents	1	1
Caspase-8 activation	1	1
Cyclin D1 Down-Regulation	1	1
Cyclooxygenase Inhibitors	1	1
Gluconeogenesis Inhibitor	1	1
Heat Shock Protein Down-Regulation	1	1
Insulin-releasing	1	1
Lactate Dehydrogenase A Inhibitor	1	1
Neurominidase Inhibitor	1	1
P21 Activation	1	1
Prostaglandin PGE2 downregulation	1	1
Reverse Transcriptase Inhibitors	1	1
Telomerase Inhibitor	1	1
Vascular Cell Adhesion Molecule-1 Inhibitor	1	1
Viral Hemagglutinin Inhibitor	1	1

[+]

A systematic review of the literature showed that Permixon was effective for relieving urinary symptoms due to prostate enlargement.Nov 30, 2016

Click here to read the entire abstract

Pubmed Data : Eur Urol Focus. 2016 Dec ;2(5):553-561. Epub 2016 Apr 23. PMID: 28723522

Article Published Date : Nov 30, 2016

Study Type : Meta Analysis, Review

Additional Links

Substances : Saw Palmetto

Diseases : Prostatic Hyperplasia: Benign

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

Evening primrose oil is a safe medication with similar efficacy for pain control in women with mastalgia to topical NSAIDS, danazol, or vitamin E.Jun 09, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Environ Res Public Health. 2021 Jun 10 ;18(12). Epub 2021 Jun 10. PMID: 34200727

Article Published Date : Jun 09, 2021

Study Type : Meta Analysis, Review

Additional Links

Substances : Evening Primrose Oil

Diseases : Mastalgia

Pharmacological Actions : Analgesics

Additional Keywords : Natural Substances Versus Drugs

[+]

Ginkgo biloba, chamomile and kava kava exhibit therapeutic potential in generalizaed anxiety disorder.Oct 15, 2010

Click here to read the entire abstract

Pubmed Data : Rev Bras Psiquiatr. 2010 Oct 15. Epub 2010 Oct 15. PMID: 20963375

Article Published Date : Oct 15, 2010

Study Type : Meta Analysis

Additional Links

Substances : Chamomile, Ginkgo biloba, Kava Kava

Diseases : Generalized Anxiety Disorder

Additional Keywords : Benzodiazepine Alternatives, Benzodiazepine Receptor Agonist, Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs

[+]

Saffron was effective in the treatment of major depressive disorder and had comparable efficacy to synthetic antidepressants.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Neuropsychiatr Dis Treat. 2018 ;14:1297-1305. Epub 2018 May 21. PMID: 29849461

Article Published Date : Dec 31, 2017

Study Type : Meta Analysis

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

The findings of this study showed that saffron administration was well comparable with fluoxetine and placebo.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Psychol Res Behav Manag. 2019 ;12:297-305. Epub 2019 Apr 23. PMID: 31118846

Article Published Date : Dec 31, 2018

Study Type : Meta Analysis, Review

Additional Links

Substances : Saffron

Diseases : Depression

Pharmacological Actions : Antidepressive Agents

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Fluoxetine (trade name Prozac)

[+]

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2005 Feb 28 ;97(2):281-4. Epub 2005 Jan 6. PMID: 15707766

Article Published Date : Feb 27, 2005

Click here to read the entire abstract

Pubmed Data : Phytother Res. 2013 Jul 6. Epub 2013 Jul 6. PMID: 23832433

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Res Med Sci. 2014 Aug ;19(8):758-61. PMID: 25422662

Article Published Date : Jul 31, 2014

Study Type : Human Study

Additional Links

Substances : Dill

Diseases : Hypercholesterolemia, Hyperlipidemia

Pharmacological Actions : Anticholesteremic Agents, Hypolipidemic

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Gemfibrozil

[+]

Dill was as effective as mefenamic acid in reducing the pain severity in primary dysmenorrhea.Mar 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Res Med Sci. 2014 Apr ;19(4):326-30. PMID: 25097605

Article Published Date : Mar 31, 2014

Study Type : Human Study

Additional Links

Substances : Dill

Diseases : Dysmenorrhea

Pharmacological Actions : Analgesics

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Mefenamic acid

[+]

Echinacea/sage is at least as effective as chlorhexidine/lidocaine for treating acute sore throats. Sep 01, 2009

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Medicine (Baltimore). 2020 Jul 10 ;99(28):e20373. PMID: 32664057

Article Published Date : Jul 09, 2020

Study Type : Human Study

Additional Links

Substances : Boswellia, Turmeric

Diseases : Pain, Pain: Musculoskeletal

Pharmacological Actions : Analgesics

Additional Keywords : Natural Substances Versus Drugs, Tylenol Alternative

[+]

Efficacy of oil pulling therapy with coconut oil on four-day supragingival plaque growth.Nov 30, 2019

Click here to read the entire abstract

Pubmed Data : Complement Ther Med. 2019 Dec ;47:102193. Epub 2019 Sep 4. PMID: 31780023

Article Published Date : Nov 30, 2019

Study Type : Human Study

Additional Links

Substances : Coconut Oil

Diseases : Dental Plaque

Additional Keywords : Natural Substances Versus Drugs

[+]

Fennel extract/vitamin E compares favorably with ibuprofen on the pain intensity in students with primary dysmenorrhea.Aug 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Iran J Nurs Midwifery Res. 2013 Sep ;18(5):355-9. PMID: 24403936

Article Published Date : Aug 31, 2013

Study Type : Human Study

Additional Links

Substances : Fennel

Diseases : Dysmenorrhea

Additional Keywords : Natural Substances Versus Drugs

Problem Substances : Mefenamic acid

[+]

Fennel is safe and effective for treating primary dysmenorrhea. Feb 01, 2003

Click here to read the entire abstract

Pubmed Data : Int J Gynaecol Obstet. 2003 Feb;80(2):153-7. PMID: 12566188

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Clin Pharm. 2018 Oct ;40(5):1335-1341. Epub 2018 Jun 1. PMID: 29855986

Article Published Date : Sep 30, 2018

Study Type : Human Study

Additional Links

Substances : Ginkgo biloba

Diseases : Tinnitus

Pharmacological Actions : Vasodilator Agents

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

Ginkgo is effective in treating pulmonary interstitial fibrosis.Mar 01, 2005

Click here to read the entire abstract

Pubmed Data : Zhongguo Zhong Xi Yi Jie He Za Zhi. 2005 Mar;25(3):222-4. PMID: 15842142

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Med Pharm Rep. 2019 Oct ;92(4):352-355. Epub 2019 Oct 25. PMID: 31750434

Article Published Date : Sep 30, 2019

Study Type : Human Study

Additional Links

Substances : Lactobacillus reuteri

Diseases : Dyspepsia, Helicobacter Pylori Infection

Pharmacological Actions : Anti-Bacterial Agents

Additional Keywords : Natural Substances Versus Drugs

[+]

Lavender oil has antifungal activity and can be used as an antifungal agent against C. albicans.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Scientifica (Cairo). 2015 ;2015:261397. Epub 2015 Oct 13. PMID: 26550521

Focus Your Research

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View the Evidence: 526 Abstracts with Natural Substances Versus Drugs Research

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A systematic review of the literature showed that Permixon was effective for relieving urinary symptoms due to prostate enlargement.Nov 30, 2016

Evening primrose oil is a safe medication with similar efficacy for pain control in women with mastalgia to topical NSAIDS, danazol, or vitamin E.Jun 09, 2021

Ginkgo biloba, chamomile and kava kava exhibit therapeutic potential in generalizaed anxiety disorder.Oct 15, 2010

Saffron was effective in the treatment of major depressive disorder and had comparable efficacy to synthetic antidepressants.Dec 31, 2017

The findings of this study showed that saffron administration was well comparable with fluoxetine and placebo.Dec 31, 2018

The results confirm the efficacy of the three herbal active substances in elderly patients with anxiety, depression, and dementia.Jun 19, 2015

Topical mother's milk may provide an effective alternative to topical antibiotics in infant epiphora. Feb 01, 2007

Zingiberaceae extracts are clinically effective hypoalgesic agents and the available data show a better safety profile than non steroidal anti inflammatory drugs.Dec 31, 2014

The intraluminal administration of peppermint oil by using a hand pump is a simple, safe, and convenient alternative to the systemic injection of a cholinergic blocking agent or glucagon during colonoscopy.Feb 01, 2001

2% dill vaginal suppositories were as effective as 100 mg clotrimazole vaginal tablets in reducing both the clinical and microbiological symptoms.Mar 18, 2018

A combination of baicalin (a compound found within Chinese skullcap) and catechin (a polyphenol plant antioxidant) are as effective as naproxen in treating osteoarthritis of the knee. Dec 01, 1985

A combination of garlic, mullein, calendula, st. johns wort and olive oil is as effective as an anesthetic drug for the management of acute otitis media-associated pain. Jul 01, 2001

A combination of nasturtium herb and horseradish root is as effetive in treating acute sinusitis, acute bronchitis and acute urinary tract infections as comparable to treatment with standard antibiotics. Jan 01, 2006

A Comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches.Dec 31, 2021

A diet high in plant sterols, vegetable proteins, viscous fibers and almonds is as effective as the statin drug lovastatin in managing hypercholesterolemia. Jul 23, 2003

A homeopathic combination (Vertigoheel) reduced the frequency, duration, and intensity of vertigo attacks and compared favorably to the drug betahistine hydrochloride. Aug 01, 1998

A homeopathic gel compares favorably to NSAID gel for treating osteoarthritis of the knee.Jul 01, 2000

A homeopathic ointment preparation compares favorably with 1% diclofenac gel for acute symptomatic treatment of tendinopathy.Nov 01, 2005

A horsetail extract produced a diuretic effect that was stronger than that of the negative control and was equivalent to that of hydrochlorothiazide.Dec 31, 2013

A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress. Jan 01, 2008

Acupuncture is as effective as low-dose prednisolone for mild-to-moderate carpal tunnel syndrome. May 01, 2009

Administration of olive oil followed by a low volume of polyethylene glycol-electrolyte lavage solution improves patient satisfaction with right-side colonic cleansing over conventional preparation. Sep 01, 2009

Administration of saffron capsules was comparable with memantine in reducing cognitive decline in patients with moderate to severe AD.Jun 30, 2014

Aloe vera and tea tree oil mouthwashes can decrease plaque, gingivitis and S. mutans in the oral cavity in children.May 19, 2019

Aloe vera gel has been shown to be as effective as benzyl benzoate in the treatment of scabies. Mar 09, 2009

Aloe vera may prove an effective mouthwash due to its ability in reducing dental plaque.Mar 31, 2014

Aloe vera mouthwash has comparable antiplaque efficacy as the gold standard 0.2% chlorhexidine gluconate with fewer side effects.Apr 30, 2016

Aloe vera mouthwash was as beneficial as benzydamine mouthwash in alleviating the severity of radiation-induced mucositis.Dec 31, 2014

An extract of saw palmetto compares favorably with the drug tamsulosin in the treatment of benign prostatic hyperplasia. Jun 01, 2002

An herbal extract combination (Biochanin A, Acetyl tetrapeptide-3, and ginseng extracts) versus 3% minoxidil solution for the treatment of androgenetic alopecia.Sep 30, 2020

Arnica is superior to steroids for reducing adverse effects, e.g. bruising, from rhinoplastic surgery. Jul 01, 2007

Arnica montana is efficacious in healing wound associated with Hallux valgus (bunion) surgery. Jan 01, 2008

Berberine is a potent oral hypoglycemic agent with benefical effects on lipid metabolism, comparable in efficacy to metformin. May 01, 2008

Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression.Oct 06, 2009

Bioavailable turmeric extract is as effective as paracetamol in reducing pain and other symptoms of knee osteoarthritis.Jan 29, 2021

Black chokeberry juice lowered the incidence of Urinary tract infections by 55% and a reduction in antibiotics use in patients. May 31, 2014

Black cohosh compares favorably to fluoxetine in the treatment of postmenopausal symptoms.Feb 28, 2007

Black cumin possesses clinical useful anti-H. pylori activity compared to triple therapy.Jul 01, 2010

Both hyaluronic acid vaginal gel and estriol cream can significantly improve the clinical symptoms of vaginal dryness in postmenopausal women, with improvement rate of 84.44% and 89.42%, respectively, after 10 applications, without statistically significaMay 31, 2013

Bright light treatment, both as monotherapy and in combination with fluoxetine, was efficacious and well tolerated in the treatment of adults with nonseasonal Nonseasonal Major Depressive Disorder.Dec 31, 2015

Butterbur is as effective as fexofenadine in attenuating nasal symptoms in patients with perennial allergic rhinitis. Apr 01, 2004

Caffeine compares favorably to amphetamine in reducing the symptoms of treatment-resistant obsessive-compulsive disorder.Nov 01, 2009

Caffeine is as effective as aminophylline, while it is superior to aminophylline regarding its overall safety.Dec 31, 2017

Castor oil is safe and effective in the treatment of patients wtih osteoarthritis. Oct 01, 2009

Celadrin, a proprietary formula containing Cetyl Myristoleate, improves knee function in patients with osteoarthritisAug 01, 2002

Chamomile extract produced a clinically meaningful reduction in generalized anxiety disorder symptoms over 8 weeks.Dec 14, 2016

Chamomile extract reduced biofilm accumulation and gingival bleeding in patients with gingivitis.Dec 31, 2015

Chamomile is as effective as clotrimazole in vulvovaginal candidiasis treatment.Dec 30, 2021

Cinnamon as compared significantly reduces the severity and duration of pain during menstruation, but this effect is less compared to that of Ibuprofen.Mar 31, 2015

Clove is as effective as benzocaine as a topical anesthesic.Nov 01, 2006

Coconut oil gargling is as effective as using chlorhexidine mouthwash for the reduction of S. mutans.Aug 31, 2016

Comparable efficacy of standardized Ayurveda formulation and hydroxychloroquine sulfate (HCQS) in the treatment of rheumatoid arthritis (RA).Jan 31, 2012

Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.Jan 31, 2013

Consumption of rose oil soft capsule alleviates cardinal GERD symptoms similar to omeprazole.Apr 30, 2021

Continual intake of a probiotic drink containing Lactobacillus brevis led to a reduction in the incidence of influenza, especially in subjects not inoculated with influenza vaccine.Nov 30, 2014

Cranberry compares favorably to the drug trimethoprim in the prevention of recurrent urinary tract infections in older women, without increasing the risk of antibiotic resistance/super-infection and/or fungal infection. Feb 01, 2009

Crocin is effective in treatment of patients with mild to moderate OCD with possibly fewer adverse effects compared to fluoxetine.Feb 17, 2021

Crocus sativus compares favorably in the treatment of mild to moderate depression. Feb 27, 2005

Curcuma longa Linn can improve dyspeptic symptoms, improve quality of life, and provide satisfaction equivalent to omeprazole.Oct 14, 2021

Curcumin compares favorably with corticosteroid therapy in the management of chronic anterior uveitis.Jun 01, 1999

Curcumin is comparable to chlorhexidine as an anti-inflammatory mouthwash. Thus, it can be considered as an effective adjunct to mechanical periodontal therapy.Dec 31, 2012

Curcumin is safe and efficacious in treating major depressive disorder.Jul 05, 2013

Cyclic antibiotic therapy in combination with fiber for diverticular disease results in very little benefit in comparison to fiber alone.Sep 01, 2010

Dietary flaxseed lignan improves lower urinary tract symptoms in benign prostatic hyperplasia subjects as well as drug therapy. Jan 01, 2007

Dietary soy supplementation constitutes an effective alternative therapy for somatic and urogenital symptoms of the menopause.Nov 01, 2010

Dill might be beneficial for hypercholesterolemic and hypertriglycemic patients.Jul 31, 2014

Dill was as effective as mefenamic acid in reducing the pain severity in primary dysmenorrhea.Mar 31, 2014

Echinacea/sage is at least as effective as chlorhexidine/lidocaine for treating acute sore throats. Sep 01, 2009

Effectiveness of ginger powder for the management of pain and gingival inflammation following open flap debridement is comparable to that of ibuprofen.Jul 01, 2020

Effects of psilocybin therapy on personality structure.Oct 31, 2018

Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study.Dec 31, 2013

Efficacy and short-term safety of topical Dwarf Elder (Sambucus ebulus L.) versus diclofenac for knee osteoarthritis.Jul 20, 2016

Natural Substances Versus Drugs

View the Evidence:
526 Abstracts with Natural Substances Versus Drugs Research