Procyanidins

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2 Problem Substances Researched for Procyanidins
NameACCKFocus
Lead12Locked
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)11Locked
18 Diseases Researched for Procyanidins
NameACCKFocus
Hair Loss110Locked
Colon Cancer15Locked
Colon Cancer: Prevention15Locked
Insulin Resistance23Locked
Osteoarthritis23Locked
Atherosclerosis12Locked
Cervical Cancer22Locked
Chemically-Induced Liver Damage12Locked
Diabetes Mellitus: Type 212Locked
Hypertension: Pulmonary12Locked
Obesity12Locked
Oxidative Stress22Locked
Cardiovascular Diseases11Locked
Gaucher Disease11Locked
Inflammation11Locked
Lipid Metabolism: Abnormalities11Locked
Liver Cancer11Locked
Tay-Sachs Disease11Locked
19 Substances Researched for Procyanidins
NameACCKFocus
Apple Polyphenols212Locked
Procyanidin B2 110Locked
Black Currant15Locked
Blackberry15Locked
Blueberry15Locked
Cranberry15Locked
Grape Seed Extract35Locked
Indian Gooseberry15Locked
Lingonberry15Locked
Raspberry15Locked
Lotus 23Locked
Pine Bark Extract23Locked
Apple12Locked
Lychee12Locked
Anthocyanins11Locked
Chokeberry11Locked
Hawthorn11Locked
Polyphenols11Locked
Sea buckthorn11Locked
17 Pharmacological Actions Researched for Procyanidins
NameACCKFocus
Antioxidants58Locked
Apoptotic26Locked
Anti-Inflammatory Agents35Locked
Caspase-8 activation15Locked
Chemopreventive15Locked
Hepatoprotective35Locked
Chondroprotective12Locked
Cyclooxygenase 2 Inhibitors12Locked
MicroRNA modulator12Locked
Nrf2 activation12Locked
Vascular Endothelial Growth Factor Inhibitors12Locked
Anti-Apoptotic11Locked
Antiproliferative 11Locked
Autophagy Up-regulation11Locked
Cardioprotective11Locked
Hypolipidemic11Locked
NF-kappaB Inhibitor11Locked

View the Evidence:
14 Abstracts with Procyanidins Research

[+]

Apple procyanidin B2 on keratin biosynthesis in vitro, and highlights its effect as a nutraceutical on human hair growth and tropism.Sep 27, 2017

Pubmed Data : J Med Food. 2017 Sep 28. Epub 2017 Sep 28. PMID: 28956697
Article Published Date : Sep 27, 2017
Study Type : Human In Vitro, Human Study
Additional Links
Substances : Apple Polyphenols, Procyanidin B2
Diseases : Hair Loss
Additional Keywords : Hair Regeneration, Procyanidins
[+]

The present work emphasizes the potential of berries in chemoprevention, especially CRC chemoprevention.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2015;2015:154164. Epub 2015 Jun 9. PMID: 26180579
Article Published Date : Dec 31, 2014
Study Type : Human In Vitro
Additional Links
Substances : Black Currant, Blackberry, Blueberry, Cranberry, Indian Gooseberry, Lingonberry, Raspberry
Diseases : Colon Cancer, Colon Cancer: Prevention
Pharmacological Actions : Apoptotic, Caspase-8 activation, Chemopreventive
Additional Keywords : Dietary Concentrations, Growing Your Own Food, Procyanidins
[+]

Administered apple procyanidins ameliorate insulin resistance by improving hepatic insulin signalling through suppression of hepatic inflammation.Nov 22, 2016

Pubmed Data : J Agric Food Chem. 2016 Nov 23 ;64(46):8857-8865. Epub 2016 Nov 10. PMID: 27792335
Article Published Date : Nov 22, 2016
Study Type : Animal Study
Additional Links
Substances : Apple Polyphenols
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
Additional Keywords : Procyanidins
[+]

Grape seed procyanidin extract ameliorates lead-induced liver injury.Jan 31, 2018

Pubmed Data : J Nutr Biochem. 2018 Feb ;52:115-123. Epub 2017 Oct 12. PMID: 29175668
Article Published Date : Jan 31, 2018
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Antioxidants, Hepatoprotective, MicroRNA modulator, Nrf2 activation
Additional Keywords : Procyanidins
Problem Substances : Lead
[+]

Grape seed procyanidin suppresses inflammation caused by cigarette smoke.Sep 29, 2019

Pubmed Data : Nutr Metab Cardiovasc Dis. 2019 Sep 30. Epub 2019 Sep 30. PMID: 31791634
Article Published Date : Sep 29, 2019
Study Type : Animal Study
Additional Links
Substances : Grape Seed Extract
Diseases : Hypertension: Pulmonary
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors
Additional Keywords : Procyanidins
[+]

Non-absorbable apple procyanidins prevent obesity associated with gut microbial and metabolomic changes.Aug 09, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 Aug 10 ;6:31208. Epub 2016 Aug 10. PMID: 27506289
Article Published Date : Aug 09, 2016
Study Type : Animal Study
Additional Links
Substances : Apple
Diseases : Obesity
Additional Keywords : Anti-Obesity Agents, Microbiota, Procyanidins
[+]

Procyanidins extracted from the litchi pericarp ameliorate atherosclerosis.Oct 17, 2017

Pubmed Data : Food Funct. 2017 Oct 18. Epub 2017 Oct 18. PMID: 29043330
Article Published Date : Oct 17, 2017
Study Type : Animal Study
Additional Links
Substances : Lychee
Diseases : Atherosclerosis
Pharmacological Actions : Antioxidants
Additional Keywords : Procyanidins
[+]

These findings suggest procyanidins can be used to mitigate osteoarthritis pathogenesis.Dec 08, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2016 Dec 9 ;17(12). Epub 2016 Dec 9. PMID: 27941690
Article Published Date : Dec 08, 2016
Study Type : Animal Study
Additional Links
Substances : Pine Bark Extract
Diseases : Osteoarthritis
Pharmacological Actions : Chondroprotective, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Chondroprotective, osteoarthritis, pine bark extract, Procyanidins, Vascular Endothelial Growth Factor Inhibitors
[+]

Chokeberry extracts inhibited HeLa cells cell proliferation after 48 h of treatment.Jul 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Food. 2012 Aug ;15(8):700-6. Epub 2012 Jun 25. PMID: 22846076
Article Published Date : Jul 31, 2012
Study Type : In Vitro Study
Additional Links
Substances : Anthocyanins, Chokeberry
Diseases : Cervical Cancer
Pharmacological Actions : Antioxidants, Antiproliferative
Additional Keywords : Dose Response, Plant Extracts, Procyanidins
[+]

Grape seed procyanidins suppress the apoptosis and senescence of chondrocytes and ameliorates osteoarthritis.Nov 30, 2020

Pubmed Data : Food Funct. 2020 Dec 1 ;11(12):10493-10505. Epub 2020 Nov 11. PMID: 33175932
Article Published Date : Nov 30, 2020
Study Type : In Vitro Study
Additional Links
Substances : Grape Seed Extract
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Apoptotic
Additional Keywords : Procyanidins
[+]

Pine bark extract could reduce viability and induce apoptosis in HeLa cells.Mar 31, 2014

Pubmed Data : Rev Med Chir Soc Med Nat Iasi. 2014 Apr-Jun;118(2):551-7. PMID: 25076730
Article Published Date : Mar 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Pine Bark Extract, Polyphenols
Diseases : Cervical Cancer
Pharmacological Actions : Apoptotic
Additional Keywords : Plant Extracts, Procyanidins
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Procyanidins from hawthorn alleviate lipid metabolism disorder via inhibiting insulin resistance and oxidative stress, normalizing the gut microbiota structure.Jul 17, 2022

Pubmed Data : Food Funct. 2022 Jul 18 ;13(14):7901-7917. Epub 2022 Jul 18. PMID: 35781311
Article Published Date : Jul 17, 2022
Study Type : In Vitro Study
Additional Links
Substances : Hawthorn
Diseases : Gaucher Disease, Inflammation, Insulin Resistance, Lipid Metabolism: Abnormalities, Oxidative Stress, Tay-Sachs Disease
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Hypolipidemic, NF-kappaB Inhibitor
Additional Keywords : Procyanidins
[+]

Procyanidins from lotus seedpod induced autophagy and autophagic cell death in HepG2 cells.Mar 31, 2016

Pubmed Data : Biomed Pharmacother. 2016 Apr ;79:135-52. Epub 2016 Feb 22. PMID: 27044822
Article Published Date : Mar 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Lotus
Diseases : Liver Cancer
Pharmacological Actions : Autophagy Up-regulation
Additional Keywords : Dose Response, Procyanidins
[+]

Regulatory effect of sea-buckthorn procyanidins on oxidative injury HUVECs. Dec 31, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Nutr. 2022 ;9:850076. Epub 2022 May 17. PMID: 35656158
Article Published Date : Dec 31, 2021
Study Type : In Vitro Study
Additional Links
Substances : Sea buckthorn
Diseases : Cardiovascular Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Cardioprotective
Additional Keywords : Procyanidins

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