Prostatic Hyperplasia

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1 Problem Substances Researched for Prostatic Hyperplasia

Name	AC	CK	Focus
Bisphenol A	2	4

11 Diseases Researched for Prostatic Hyperplasia

Name	AC	CK
Prostatic Hyperplasia	23	107
Lower Urinary Tract Symptoms	1	10
Prostate: PSA Doubling	1	10
Bisphenol Toxicity	1	2
Inflammation	1	2
Alzheimer's Disease	1	1
Endometriosis	1	1
Menopausal Syndrome	1	1
Osteoporosis	1	1
Polycystic Ovary Syndrome	1	1
Prostate Cancer	1	1

23 Substances Researched for Prostatic Hyperplasia

Name	AC	CK
Curcumin	2	12
Saw Palmetto	2	12
Curcumin: Lipidated	1	10
Milk Thistle	1	10
Pumpkin Seeds	1	10
Selenium	1	10
Syrian rue	1	10
Babchi	1	2
Chrysin	1	2
Date Palm Pollen	1	2
Dogwood	1	2
Flavonoids	1	2
Garcinia kola	1	2
Lycopene	1	2
Nettle	1	2
Onion	1	2
Papaya	1	2
Pueraria mirifica	1	2
Banana	1	1
Berbamine	1	1
Cucurbitacin B	1	1
Ginger	1	1
Glycyrrhiza uralensis	1	1

2 Therapeutic Actions Researched for Prostatic Hyperplasia

Name	AC	CK	Focus
Acupuncture	1	20
Qigong	1	10

17 Pharmacological Actions Researched for Prostatic Hyperplasia

Name	AC	CK
Anti-Inflammatory Agents	5	17
Antioxidants	2	12
Antiproliferative	6	10
Cyclooxygenase 2 Inhibitors	3	4
Interleukin-6 Downregulation	2	4
Tumor Necrosis Factor (TNF) Alpha Inhibitor	2	4
Apoptotic	2	3
Anti-Proliferative	1	2
Cell cycle arrest	1	2
Immunomodulatory	1	2
Interleukin-1 beta downregulation	1	2
anti-inflammatory	1	2
Chemopreventive	1	1
Neuroprotective Agents	1	1
Osteoprotective	1	1
Postaglandin PGE2 downregulation	1	1
Tumor Suppressor Protein p53 Upregulation	1	1

Research Articles 23
Cumulative Knowledge Score 37
Overall Research Rating GOOD

View the Evidence:
23 Abstracts with Prostatic Hyperplasia Research

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[+]

Statistically significant changes were observed in favour of acupuncture in moderate to severe benign prostatic hyperplasia.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : PLoS One. 2017 ;12(4):e0174586. Epub 2017 Apr 4. PMID: 28376120

Article Published Date : Dec 31, 2016

Study Type : Meta Analysis, Review

Additional Links

Diseases : Prostatic Hyperplasia

Therapeutic Actions : Acupuncture

[+]

A combination of selenium and silymari led to a significant reduction in PSA levels.Dec 14, 2013

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2013 Dec 15 ;21(1):75-81. Epub 2013 Sep 5. PMID: 24012146

Article Published Date : Dec 14, 2013

Study Type : Human Study

Additional Links

Substances : Milk Thistle, Selenium

Diseases : Prostate: PSA Doubling, Prostatic Hyperplasia

Additional Keywords : Natural Substance Synergy, Phytotherapy, Plant Extracts

[+]

Application of Peganum harmala seed can be useful in reducing urinary symptoms in patients with benign prostatic hyperplasia.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Renal Inj Prev. 2017 ;6(2):127-131. Epub 2016 Dec 18. PMID: 28497089

Article Published Date : Dec 31, 2016

Study Type : Human Study

Additional Links

Substances : Syrian rue

Diseases : Prostatic Hyperplasia

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Natural Substance/Drug Synergy

[+]

Beneficial effects of Saw palmetto fruit extract on urinary symptoms in Japanese female subjects.Mar 10, 2022

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2022 Mar 11 ;14(6). Epub 2022 Mar 11. PMID: 35334848

Article Published Date : Mar 10, 2022

Study Type : Human Study

Additional Links

Substances : Saw Palmetto

Diseases : Lower Urinary Tract Symptoms, Prostatic Hyperplasia

Additional Keywords : Plant Extracts

[+]

In patients with BPH, the addition of Meriva® to the standard treatment contributed to the reduction of signs and symptoms of the disease without causing any significant additional side effect.Nov 30, 2012

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Panminerva Med. 2012 Dec ;54(1 Suppl 4):17-22. PMID: 23241931

Article Published Date : Nov 30, 2012

Study Type : Human Study

Additional Links

Substances : Curcumin, Curcumin: Lipidated

Diseases : Prostatic Hyperplasia

[+]

The results showed that Yi Jin Jing is a promising way to reduce the risk of benign prostatic hyperplasia-lower urinary tract symptoms in older men.May 19, 2020

Click here to read the entire abstract

Pubmed Data : J Aging Phys Act. 2020 May 20:1-6. Epub 2020 May 20. PMID: 32434151

Article Published Date : May 19, 2020

Study Type : Human Study

Additional Links

Diseases : Prostatic Hyperplasia

Therapeutic Actions : Qigong

[+]

Treatment with pumpkin seed led to a clinically relevant reduction in international prostate symptom score compared with placebo.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Urol Int. 2015 ;94(3):286-95. Epub 2014 Sep 5. PMID: 25196580

Article Published Date : Dec 31, 2014

Study Type : Human Study

Additional Links

Substances : Pumpkin Seeds

Diseases : Prostatic Hyperplasia

Additional Keywords : Plant Extracts

[+]

An extract of red onion scales showed a protective effect against atypical prostatic hyperplasia.Dec 31, 2013

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Mediators Inflamm. 2014 ;2014:640746. Epub 2014 Apr 13. PMID: 24829522

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Substances : Onion

Diseases : Prostatic Hyperplasia

Pharmacological Actions : Immunomodulatory, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Anti-inflammatory and antiproliferative activities of date palm pollen (Phoenix dactylifera) on experimentally-induced atypical prostatic hyperplasia in rats.Dec 31, 2010

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Inflamm (Lond). 2011 ;8(1):40. Epub 2011 Dec 23. PMID: 22195697

Article Published Date : Dec 31, 2010

Study Type : Animal Study

Additional Links

Substances : Date Palm Pollen

Diseases : Prostatic Hyperplasia

Pharmacological Actions : anti-inflammatory, Anti-Proliferative

[+]

Bisphenol AF induces prostatic dorsal lobe hyperplasia.Nov 11, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2023 Nov 12 ;24(22). Epub 2023 Nov 12. PMID: 38003411

Article Published Date : Nov 11, 2023

Study Type : Animal Study

Additional Links

Diseases : Bisphenol Toxicity, Prostatic Hyperplasia

Problem Substances : Bisphenol A

[+]

Carica papaya leaf extract inhibits prostatitis-associated prostatic hyperplasia.Feb 28, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biomed Pharmacother. 2021 Mar ;135:111197. Epub 2021 Feb 1. PMID: 33433362

Article Published Date : Feb 28, 2021

Study Type : Animal Study

Additional Links

Substances : Papaya

Diseases : Prostatic Hyperplasia

Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Cyclooxygenase 2 Inhibitors

[+]

Chrysin attenuates testosterone-induced benign prostate hyperplasia in rats.Dec 31, 2017

Click here to read the entire abstract

Pubmed Data : Food Chem Toxicol. 2018 Jan ;111:650-659. Epub 2017 Dec 14. PMID: 29247772

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Chrysin

Diseases : Prostatic Hyperplasia

Pharmacological Actions : Antioxidants, Antiproliferative , Apoptotic

[+]

Combination of lycopene and curcumin synergistically alleviates testosterone-propionate-induced benign prostatic hyperplasia.Jun 20, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2023 Jun 21 ;28(13). Epub 2023 Jun 21. PMID: 37446563

Article Published Date : Jun 20, 2023

Study Type : Animal Study

Additional Links

Substances : Curcumin, Lycopene

Diseases : Inflammation, Prostatic Hyperplasia

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Combined Sabal and Urtica extracts exert anti-proliferative and anti-inflammatory effects in a model of benign prostate hyperplasia.Dec 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2019 ;10:311. Epub 2019 Mar 29. PMID: 30984003

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Nettle, Saw Palmetto

Diseases : Prostatic Hyperplasia

Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative

Additional Keywords : Plant Extracts

[+]

Cornus officinalis and Psoralea corylifolia extracts suppresses benign prostate hyperplasia.May 01, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2019 May 2 ;24(9). Epub 2019 May 2. PMID: 31052610

Article Published Date : May 01, 2019

Study Type : Animal Study

Additional Links

Substances : Babchi, Dogwood

Diseases : Prostatic Hyperplasia

Pharmacological Actions : Antiproliferative , Cell cycle arrest

Additional Keywords : Plant Extracts

[+]

Preventive effect of Pueraria mirifica on testosterone-induced prostatic hyperplasia in Sprague Dawley rats.Nov 30, 2015

Click here to read the entire abstract

Pubmed Data : Andrologia. 2015 Dec ;47(10):1153-9. Epub 2015 Jan 20. PMID: 25600492

Article Published Date : Nov 30, 2015

Study Type : Animal Study

Additional Links

Substances : Pueraria mirifica

Diseases : Prostatic Hyperplasia

Additional Keywords : Phytotherapy, Plant Extracts

[+]

The normal rats administered finasteride or kolaviron had decreased prostate weights.Sep 30, 2016

Click here to read the entire abstract

Pubmed Data : Biomed Pharmacother. 2016 Oct ;83:1436-1443. Epub 2016 Sep 6. PMID: 27599375

Article Published Date : Sep 30, 2016

Study Type : Animal Study

Additional Links

Substances : Flavonoids, Garcinia kola

Diseases : Prostatic Hyperplasia

Additional Keywords : Natural Substances Versus Drugs, Plant Extracts

[+]

These data suggest that expression of Scgb2a1 in the adult prostate could be epigenetically reprogrammed by BPA exposure during prostate development.Dec 31, 2014

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Epigenetics. 2015 ;10(2):127-34. PMID: 25612011

Article Published Date : Dec 31, 2014

Study Type : Animal Study

Additional Links

Diseases : Prostatic Hyperplasia

Additional Keywords : Risk Factors

Problem Substances : Bisphenol A

[+]

Banana flower extract suppresses benign prostatic hyperplasia.Oct 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : In Vivo. 2018 Nov-Dec;32(6):1373-1379. PMID: 30348691

Article Published Date : Oct 31, 2018

Study Type : In Vitro Study

Additional Links

Substances : Banana

Diseases : Prostatic Hyperplasia

Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Cyclooxygenase 2 Inhibitors, Postaglandin PGE2 downregulation

Additional Keywords : Plant Extracts

[+]

Berbamine inhibits the biological activities of prostate cancer cells.Dec 31, 2022

Click here to read the entire abstract

Pubmed Data : Anticancer Agents Med Chem. 2023 ;23(14):1626-1633. PMID: 37638593

Article Published Date : Dec 31, 2022

Study Type : In Vitro Study

Additional Links

Substances : Berbamine

Diseases : Prostate Cancer, Prostatic Hyperplasia

Pharmacological Actions : Antiproliferative

[+]

Nutritional implications of ginger: chemistry, biological activities and signaling pathways.Aug 18, 2020

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2020 Aug 19 ;86:108486. Epub 2020 Aug 19. PMID: 32827666

Article Published Date : Aug 18, 2020

Study Type : Review

Additional Links

Substances : Ginger

Diseases : Alzheimer's Disease, Endometriosis, Menopausal Syndrome, Osteoporosis, Polycystic Ovary Syndrome, Prostatic Hyperplasia

Pharmacological Actions : Chemopreventive, Neuroprotective Agents, Osteoprotective

[+]

The antiproliferative and proapoptotic effects of cucurbitacin B on BPH-1 cells.Dec 27, 2023

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2023 Dec 28 ;25(1). Epub 2023 Dec 28. PMID: 38203613

Article Published Date : Dec 27, 2023

Study Type : In Vitro Study

Additional Links

Substances : Cucurbitacin B

Diseases : Prostatic Hyperplasia

Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Tumor Suppressor Protein p53 Upregulation

[+]

These findings suggested that Glycyrrhiza uralensis reduces the development of benign prostatic hyperplasia.Sep 30, 2022

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2022 Oct ;105:154371. Epub 2022 Jul 31. PMID: 35964456

Article Published Date : Sep 30, 2022

Study Type : In Vitro Study

Additional Links

Substances : Glycyrrhiza uralensis

Diseases : Prostatic Hyperplasia

Pharmacological Actions : Apoptotic

Additional Keywords : Plant Extracts

Research Articles 23
Cumulative Knowledge Score 37
Overall Research Rating GOOD

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 23 Abstracts with Prostatic Hyperplasia Research

Limited to Members Only

Currently Available Sorting Options

Statistically significant changes were observed in favour of acupuncture in moderate to severe benign prostatic hyperplasia.Dec 31, 2016

A combination of selenium and silymari led to a significant reduction in PSA levels.Dec 14, 2013

Application of Peganum harmala seed can be useful in reducing urinary symptoms in patients with benign prostatic hyperplasia.Dec 31, 2016

Beneficial effects of Saw palmetto fruit extract on urinary symptoms in Japanese female subjects.Mar 10, 2022

In patients with BPH, the addition of Meriva® to the standard treatment contributed to the reduction of signs and symptoms of the disease without causing any significant additional side effect.Nov 30, 2012

The results showed that Yi Jin Jing is a promising way to reduce the risk of benign prostatic hyperplasia-lower urinary tract symptoms in older men.May 19, 2020

Treatment with pumpkin seed led to a clinically relevant reduction in international prostate symptom score compared with placebo.Dec 31, 2014

An extract of red onion scales showed a protective effect against atypical prostatic hyperplasia.Dec 31, 2013

Anti-inflammatory and antiproliferative activities of date palm pollen (Phoenix dactylifera) on experimentally-induced atypical prostatic hyperplasia in rats.Dec 31, 2010

Bisphenol AF induces prostatic dorsal lobe hyperplasia.Nov 11, 2023

Carica papaya leaf extract inhibits prostatitis-associated prostatic hyperplasia.Feb 28, 2021

Chrysin attenuates testosterone-induced benign prostate hyperplasia in rats.Dec 31, 2017

Combination of lycopene and curcumin synergistically alleviates testosterone-propionate-induced benign prostatic hyperplasia.Jun 20, 2023

Combined Sabal and Urtica extracts exert anti-proliferative and anti-inflammatory effects in a model of benign prostate hyperplasia.Dec 31, 2018

Cornus officinalis and Psoralea corylifolia extracts suppresses benign prostate hyperplasia.May 01, 2019

Preventive effect of Pueraria mirifica on testosterone-induced prostatic hyperplasia in Sprague Dawley rats.Nov 30, 2015

The normal rats administered finasteride or kolaviron had decreased prostate weights.Sep 30, 2016

These data suggest that expression of Scgb2a1 in the adult prostate could be epigenetically reprogrammed by BPA exposure during prostate development.Dec 31, 2014

Banana flower extract suppresses benign prostatic hyperplasia.Oct 31, 2018

Berbamine inhibits the biological activities of prostate cancer cells.Dec 31, 2022

Nutritional implications of ginger: chemistry, biological activities and signaling pathways.Aug 18, 2020

The antiproliferative and proapoptotic effects of cucurbitacin B on BPH-1 cells.Dec 27, 2023

These findings suggested that Glycyrrhiza uralensis reduces the development of benign prostatic hyperplasia.Sep 30, 2022

Prostatic Hyperplasia Related Articles

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Prostatic Hyperplasia

View the Evidence:
23 Abstracts with Prostatic Hyperplasia Research