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3 Problem Substances Researched for Supplementation
NameACCKFocus
Calcium Supplements110Locked
Sodium Fluoride12Locked
Statin Drugs12Locked
77 Diseases Researched for Supplementation
NameACCKFocus
Vitamin D Deficiency982Locked
Magnesium Deficiency441Locked
Oxidative Stress533Locked
Inflammation432Locked
Diabetes Mellitus: Type 2431Locked
Depression330Locked
Cardiovascular Diseases120Locked
Kidney Failure220Locked
Metabolic Diseases220Locked
Diabetes Mellitus: Type 2: Prevention211Locked
Diabetes: Oxidative Stress211Locked
Vitamin B 12 Deficiency211Locked
Athletic Performance110Locked
Athletic Performance: Recovery 110Locked
Brain Ischemia110Locked
Breast Cancer: BRCA1110Locked
C-Reactive Protein110Locked
Cardiovascular Disease: Prevention110Locked
Chemotherapy-Induced Toxicity: Cisplatin110Locked
Cholesterol: High110Locked
Chronic Kidney Disease (CKD)110Locked
Chronic Obstructive Pulmonary Disease110Locked
DNA damage110Locked
Dental Caries: Children110Locked
Depressive Disorder110Locked
Down Syndrome110Locked
Dry Eye Syndromes110Locked
Gestational Diabetes110Locked
Headache110Locked
Headache: Migraine110Locked
Hypertension110Locked
Infertility: Female110Locked
Lung Cancer110Locked
Lyme Disease110Locked
Metabolic Syndrome X110Locked
Muscle Damage110Locked
Muscle Soreness110Locked
Myelodysplastic Syndromes110Locked
Obesity110Locked
Overweight 110Locked
Spinal Cord Inflammation110Locked
Spinal Cord Injuries110Locked
Systemic Lupus Erythematosus110Locked
Triglycerides: Elevated110Locked
Vitamin E Deficiency110Locked
Breast Cancer25Locked
Alzheimer's Disease24Locked
Insulin Resistance23Locked
Alcohol Toxicity 12Locked
Anemia: Iron Deficiency12Locked
Arthritis12Locked
Bone Diseases12Locked
Bone Diseases: Over-Active Osteoclasts12Locked
Brain Inflammation 12Locked
Breast Cancer: Metastatic12Locked
Breast Cancer: Triple Negative 12Locked
Cachexia12Locked
Colon Cancer12Locked
Colon Cancer: Prevention12Locked
Drug-Induced Nutrient Depletion: Statin Drugs12Locked
Fetal Alcoholism12Locked
Fluoride Toxicity 12Locked
Hyperglycemia12Locked
Hyperlipidemia12Locked
Infertility12Locked
Melanoma12Locked
Melanoma: Metastasis12Locked
Nickel Poisoning12Locked
Radiotherapy12Locked
Athletic Performance: Strength11Locked
Folic Acid/Folate Deficiency11Locked
Liver Cancer11Locked
Menstrual Migraine11Locked
Migraine Disorders11Locked
Migraine: Menstrual Cycle Induced11Locked
Movement Disorders11Locked
Neurological Conditions11Locked
54 Substances Researched for Supplementation
NameACCKFocus
Vitamin D1397Locked
Magnesium873Locked
Coenzyme Q10542Locked
Selenium330Locked
Chlorella (Algae)220Locked
DHA (Docosahexaenoic Acid)220Locked
EPA (Eicosapentaenoic Acid)220Locked
Vitamin E414Locked
EGCG (Epigallocatechin gallate)212Locked
Probiotics212Locked
Curcumin211Locked
Riboflavin (Vitamin B-2)211Locked
Alpha-Lipoic Acid110Locked
Carnitine110Locked
Chlorophyll110Locked
Flavonoids110Locked
Flaxseed110Locked
Garlic: Aged110Locked
Ginger110Locked
Ginseng (Korean)110Locked
Ginsenosides110Locked
Maitake Mushroom110Locked
Multivitamin110Locked
Omega-3 Fatty Acids110Locked
Pumpkin Seeds110Locked
Pycnogenol (Pine Bark)110Locked
Sesame Seeds110Locked
Vitamin E: alpha tocopherol110Locked
Vitamin C46Locked
Quercetin23Locked
Astaxanthin12Locked
Choline12Locked
Cryptoxanthin12Locked
Green Tea12Locked
Lactobacillus rhamnosus 12Locked
Melatonin12Locked
Moringa oleifera12Locked
Pectin12Locked
Pomegranate12Locked
Spinach12Locked
Star Fruit12Locked
Vitamin A12Locked
Allicin11Locked
Aloe Vera11Locked
Capsaicin11Locked
Citrus naringin11Locked
Folate11Locked
Folic Acid 11Locked
Genistein11Locked
Glycyrrhizin11Locked
Piperine11Locked
Vitamin B-1211Locked
Vitamin B-611Locked
Vitamin B1211Locked
4 Therapeutic Actions Researched for Supplementation
NameACCKFocus
Exercise220Locked
Dietary Modification: Vegetarian110Locked
Fasting/Caloric Restriction110Locked
Dietary Modification: Low Carbohydrate/Ketogenic13Locked
27 Pharmacological Actions Researched for Supplementation
NameACCKFocus
Antioxidants966Locked
Antidepressive Agents330Locked
Anti-Inflammatory Agents424Locked
Malondialdehyde Down-regulation220Locked
Hypoglycemic Agents212Locked
Hypolipidemic212Locked
Interleukin-6 Downregulation212Locked
Renoprotective212Locked
Anti Inflammatory110Locked
Anticholesteremic Agents110Locked
Antihypertensive Agents110Locked
Appetite Suppresant110Locked
Chemopreventive110Locked
Chemoprotective Agents110Locked
Genoprotective110Locked
Immunomodulatory110Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor110Locked
Antiproliferative 24Locked
Hepatoprotective24Locked
Neuroprotective Agents24Locked
Anti-metastatic12Locked
Anticarcinogenic Agents12Locked
Apoptotic12Locked
Cyclooxygenase 2 Inhibitors12Locked
Fertility Agents12Locked
Interleukin-1 beta downregulation12Locked
Radioprotective12Locked

View the Evidence:
60 Abstracts with Supplementation Research

[+]

Circulating and dietary magnesium levels are inversely associated with cardiovascular disease risk.Jun 30, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Clin Nutr. 2013 Jul ;98(1):160-73. Epub 2013 May 29. PMID: 23719551
Article Published Date : Jun 30, 2013
Study Type : Meta Analysis
Additional Links
Substances : Magnesium
Diseases : Cardiovascular Diseases, Magnesium Deficiency
Additional Keywords : Risk Factors, Risk Reduction, Supplementation
[+]

A buccal spray produced a significantly higher mean serum 25(OH)D concentration compared to capsule, in both healthy and patients with malabsorption syndrome.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutr J. 2015 ;14(1):114. Epub 2015 Oct 29. PMID: 26514332
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Vitamin D Deficiency
Additional Keywords : Supplementation
[+]

A dietary mixture of sesame, pumpkin and flax seed added to a habitual diet lowered triglyceride and CRP, TNF-alpha, IL-6 levelsDec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ScientificWorldJournal. 2014 ;2014:563576. Epub 2014 Jan 22. PMID: 24578648
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Flaxseed, Pumpkin Seeds, Sesame Seeds
Diseases : Inflammation, Kidney Failure
Pharmacological Actions : Anti Inflammatory, Hypoglycemic Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Supplementation
[+]

A maitake mushroom extract has beneficial immunomodulatory potential in patients with myelodysplastic syndromes.Oct 28, 2014

Pubmed Data : Cancer Immunol Immunother. 2014 Oct 29. Epub 2014 Oct 29. PMID: 25351719
Article Published Date : Oct 28, 2014
Study Type : Human Study
Additional Links
Substances : Maitake Mushroom
Diseases : Myelodysplastic Syndromes
Pharmacological Actions : Immunomodulatory
Additional Keywords : Plant Extracts, Supplementation
[+]

Addition of green plant membranes as a dietary supplement once daily induces weight loss, improves obesity related risk factors, and reduces the urge for palatable food.Sep 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Appetite. 2014 Oct ;81:295-304. Epub 2014 Jun 30. PMID: 24993695
Article Published Date : Sep 30, 2014
Study Type : Human Study
Additional Links
Substances : Chlorophyll
Diseases : Cholesterol: High, Overweight
Pharmacological Actions : Appetite Suppresant, Hypolipidemic
Additional Keywords : Risk Reduction, Significant Treatment Outcome , Supplementation, Weight Loss
[+]

After 3 months of treatment with the supplement, a reduction of migraine pain and burden of disease was seen.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Headache Pain. 2015 ;16:516. Epub 2015 Apr 3. PMID: 25916335
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10, Magnesium, Riboflavin (Vitamin B-2)
Diseases : Headache, Headache: Migraine
Additional Keywords : Supplementation
[+]

Antiepileptic drugs might lead to disturbed vitamin D levels in patients. Jan 26, 2016

Pubmed Data : Ann Nutr Metab. 2016 Jan 27 ;68(2):119-127. Epub 2016 Jan 27. PMID: 26812357
Article Published Date : Jan 26, 2016
Study Type : Human Study
Additional Links
Diseases : Vitamin D Deficiency
Additional Keywords : Supplementation
[+]

Coenzyme supplementation may reduce oxidative stress in type 2 diabetics.Mar 31, 2015

Pubmed Data : J Pak Med Assoc. 2015 Apr ;65(4):404-8. PMID: 25976576
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2
Pharmacological Actions : Antioxidants
Additional Keywords : Supplementation
[+]

CoQ10 supplements in patients with metabolic syndrome for 8 weeks had beneficial effects on serum insulin levels, HOMA-IR, HOMA-B and plasma TAC concentrations.Sep 17, 2015

Pubmed Data : Eur J Nutr. 2015 Sep 18. Epub 2015 Sep 18. PMID: 26385228
Article Published Date : Sep 17, 2015
Study Type : Human Study
Additional Links
Substances : Coenzyme Q10
Diseases : Diabetes Mellitus: Type 2, Inflammation, Metabolic Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
Additional Keywords : Supplementation
[+]

Daily supplementation of Korean Red Ginseng for 8 weeks significantly improved the TBUT score and subjective dry eye symptoms, as compared to placebo.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2015 Jan ;39(1):7-13. Epub 2014 Jul 23. PMID: 25535471
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Ginseng (Korean), Ginsenosides
Diseases : Dry Eye Syndromes
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Significant Treatment Outcome , Supplementation
[+]

Deficiency of 25(OH)D3, a potentially modifiable risk factor, independently predicted cognitive impairment in SLE patients.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(12):e0144149. Epub 2015 Dec 4. PMID: 26636681
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Systemic Lupus Erythematosus, Vitamin D Deficiency
Additional Keywords : Risk Factors, Risk Reduction, Supplementation
[+]

EGCG decreased skeletal muscle lactate concentrations in overweight individuals, suggesting a shift towards a more oxidative muscle phenotype.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:17896. Epub 2015 Dec 9. PMID: 26647963
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Additional Keywords : Supplementation
[+]

Evidence shows that calcium supplementation may elevate brain lesions in this study. Jun 30, 2014

Pubmed Data : Br J Nutr. 2014 Jul ;112(2):220-7. Epub 2014 Apr 30. PMID: 24787048
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Diseases : Brain Ischemia
Additional Keywords : Diet, Supplementation
Problem Substances : Calcium Supplements
[+]

Garlic supplementation increased the activity of antioxidant enzymes and could possibly decrease exercise-induced oxidative damage in male athletes.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Oral Biol Craniofac Res. 2015 Sep-Dec;5(3):146-152. Epub 2015 Aug 21. PMID: 26605139
Article Published Date : Aug 31, 2015
Study Type : Human Study
Additional Links
Substances : Garlic: Aged
Diseases : Oxidative Stress
Therapeutic Actions : Exercise
Pharmacological Actions : Antioxidants
Additional Keywords : Supplementation
[+]

Ginger supplementation may be used to accelerate recovery of muscle strength following intense exerciseMay 31, 2015

Pubmed Data : Phytother Res. 2015 Jun ;29(6):887-93. Epub 2015 Mar 18. PMID: 25787877
Article Published Date : May 31, 2015
Study Type : Human Study
Additional Links
Substances : Ginger
Diseases : Muscle Damage, Muscle Soreness
Therapeutic Actions : Exercise
Additional Keywords : Supplementation
[+]

High-volume hydration and magnesium supplementation can reduce the renal toxicity induced by cisplatin.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Pharmacol Toxicol. 2014 ;15:70. Epub 2014 Dec 4. PMID: 25472655
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Lung Cancer
Pharmacological Actions : Chemoprotective Agents, Renoprotective
Additional Keywords : Significant Treatment Outcome , Supplementation
[+]

Improvement of vitamin D status may help reduce the public health burden of metabolic syndrome, and potential subsequent health conditions including type 2 diabetes and cardiovascular disease.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 ;7(9):7271-84. Epub 2015 Aug 28. PMID: 26343719
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Cardiovascular Disease: Prevention, Diabetes Mellitus: Type 2: Prevention, Metabolic Diseases
Additional Keywords : Risk Reduction, Supplementation
[+]

Improving children's vitamin D status may be an additional preventive consideration to lower the risk for caries.Nov 08, 2015

Pubmed Data : J Dent Res. 2015 Nov 9. Epub 2015 Nov 9. PMID: 26553883
Article Published Date : Nov 08, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Dental Caries: Children, Vitamin D Deficiency
Additional Keywords : Risk Factors, Supplementation
[+]

Individuals using the Army Physical Fitness Test while supplementing with Pycnogenol had a lower increase in oxidative stress with a faster recovery to almost normal levels.Nov 30, 2013

Pubmed Data : J Sports Med Phys Fitness. 2013 Dec ;53(6):644-54. PMID: 24247188
Article Published Date : Nov 30, 2013
Study Type : Human Study
Additional Links
Substances : Flavonoids, Pycnogenol (Pine Bark)
Diseases : Athletic Performance, Athletic Performance: Recovery
Pharmacological Actions : Antioxidants
Additional Keywords : Supplementation
[+]

Lyme borreliosis patients exhibit a significant decrease of their serum carnitine concentrations.Dec 31, 2015

Pubmed Data : Postepy Hig Med Dosw (Online). 2016;70(0):180-185. Epub 2016 Mar 4. PMID: 26943315
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Carnitine
Diseases : Lyme Disease
Additional Keywords : Supplementation
[+]

Magnesium supplementation among women with gestational diabetes had significant beneficial effects on metabolic status and pregnancy outcomes.May 26, 2015

Pubmed Data : Am J Clin Nutr. 2015 May 27. Epub 2015 May 27. PMID: 26016859
Article Published Date : May 26, 2015
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Gestational Diabetes, Magnesium Deficiency
Additional Keywords : Pregnancy Outcome, Risk Reduction, Supplementation
[+]

Oral cholecalciferol administration increased 25-hydroxyvitamin D and mildly reduced PTH serum levels.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Nephrol Renovasc Dis. 2015;8:151-157. Epub 2015 Nov 19. PMID: 26640388
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Kidney Disease (CKD), Vitamin D Deficiency
Additional Keywords : Supplementation
[+]

Oral magnesium supplementation improves the metabolic profile and blood pressure of MONW individuals.Jun 30, 2014

Pubmed Data : Arch Med Res. 2014 Jul ;45(5):388-93. Epub 2014 May 13. PMID: 24830937
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Substances : Magnesium
Diseases : Hypertension, Magnesium Deficiency, Metabolic Syndrome X, Obesity, Triglycerides: Elevated
Pharmacological Actions : Anticholesteremic Agents, Antihypertensive Agents
Additional Keywords : Significant Treatment Outcome , Supplementation
[+]

Oral selenium is a good candidate for chemoprevention in women who carry a mutation in the BRCA1 gene.Apr 30, 2005

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer Epidemiol Biomarkers Prev. 2005 May ;14(5):1302-6. PMID: 15894690
Article Published Date : Apr 30, 2005
Study Type : Human Study
Additional Links
Substances : Selenium
Diseases : Breast Cancer: BRCA1, DNA damage
Pharmacological Actions : Antioxidants, Chemopreventive, Genoprotective
Additional Keywords : Risk Reduction, Sodium Selenite, Supplementation
[+]

Supplementation with omega 3 fatty acids led to a significant improvement in depressive symptoms and health related quality of life in hemodialysis patients. Jun 30, 2014

Pubmed Data : Am J Ther. 2014 Jul-Aug;21(4):275-87. PMID: 24987942
Article Published Date : Jun 30, 2014
Study Type : Human Study
Additional Links
Substances : DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid), Omega-3 Fatty Acids
Diseases : Depression, Kidney Failure
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Supplementation
[+]

Targeting inflammation through diet in patients after spinal cord injury could help with depressive symptoms. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2015 ;12(1):204. Epub 2015 Nov 6. PMID: 26545369
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Chlorella (Algae), Coenzyme Q10, Curcumin, DHA (Docosahexaenoic Acid), EPA (Eicosapentaenoic Acid), Selenium, Vitamin E
Diseases : Depression, Spinal Cord Inflammation, Spinal Cord Injuries
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents
Additional Keywords : Dietary Modification, Diseases that are Linked, Supplementation
[+]

The consumption of probiotic yogurt or a multispecies probiotic capsule had beneficial effects on mental health parameters in petrochemical workers.Apr 15, 2015

Pubmed Data : Nutr Neurosci. 2015 Apr 16. Epub 2015 Apr 16. PMID: 25879690
Article Published Date : Apr 15, 2015
Study Type : Human Study
Additional Links
Substances : Probiotics
Diseases : Depression, Depressive Disorder
Pharmacological Actions : Antidepressive Agents
Additional Keywords : Supplementation
[+]

The prevalence of inadequate vitamin E levels was significantly higher among non users of dietary supplements. Dec 31, 2014

Pubmed Data : PLoS One. 2015 ;10(8):e0135510. Epub 2015 Aug 19. PMID: 26287975
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Vitamin E Deficiency
Additional Keywords : Supplementation
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The use of food supplements was not associated with excessive vitamin intake in this survey, except in a small number of cases.May 12, 2014

Pubmed Data : Int J Vitam Nutr Res. 2014 May 13 ;84(3-4):152-162. PMID: 26098479
Article Published Date : May 12, 2014
Study Type : Human Study
Additional Links
Substances : Multivitamin
Additional Keywords : Nutrional Supplements, Supplementation
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There was an inverse correlation between 25(OH) vitamin D and C-reactive protein, and this was more pronounced in patients with inflammatory diseases.Jan 07, 2016

Pubmed Data : Clin Biochem. 2016 Jan 8. Epub 2016 Jan 8. PMID: 26778547
Article Published Date : Jan 07, 2016
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : C-Reactive Protein, Inflammation, Vitamin D Deficiency
Additional Keywords : Supplementation
[+]

This study gives evidence to the high prevalence of 25(OH)D deficiency in the general population of Belgium.Jul 31, 2015

Pubmed Data : Nutr Res. 2015 Aug ;35(8):716-25. Epub 2015 Jun 15. PMID: 26149190
Article Published Date : Jul 31, 2015
Study Type : Human Study
Additional Links
Diseases : Vitamin D Deficiency
Additional Keywords : Supplementation
[+]

Vitamin B12 in chlorella is bioavailable and dietary supplementation is a natural way for vegetarians and vegans to get the vitamin B12 they need.Oct 19, 2015

Pubmed Data : J Med Food. 2015 Oct 20. Epub 2015 Oct 20. PMID: 26485478
Article Published Date : Oct 19, 2015
Study Type : Human Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Vitamin B 12 Deficiency
Therapeutic Actions : Dietary Modification: Vegetarian
Additional Keywords : Supplementation
[+]

Vitamin D intake decreased COPD exacerbation and improved FEV1 in the patients with severe and very severe COPD.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Glob J Health Sci. 2015 ;7(4):243-8. Epub 2015 Jan 14. PMID: 25946929
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Chronic Obstructive Pulmonary Disease
Additional Keywords : Supplementation
[+]

Vitamin D status is associated with specific causes of infertility and individual anthropometric characteristics.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2015 ;7(12):9972-84. Epub 2015 Dec 2. PMID: 26633484
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Infertility: Female, Vitamin D Deficiency
Additional Keywords : Supplementation
[+]

Vitamin D supplementation improves serum concentrations of magnesium and selenium in a gender-dependent manner.Dec 31, 2013

Pubmed Data : Int J Vitam Nutr Res. 2014 ;84(1-2):27-34. PMID: 25835233
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Magnesium, Selenium, Vitamin D
Diseases : Diabetes Mellitus: Type 2
Therapeutic Actions : Fasting/Caloric Restriction
Additional Keywords : Parathyroid Hormone, Supplementation
[+]

α-Tocopherol supplementation of the diets of children with down syndrome may attenuate the oxidative stress at the DNA level.Sep 30, 2014

Pubmed Data : Eur J Clin Nutr. 2014 Oct ;68(10):1119-23. Epub 2014 Jun 18. PMID: 24939437
Article Published Date : Sep 30, 2014
Study Type : Human Study
Additional Links
Substances : Alpha-Lipoic Acid, Vitamin E: alpha tocopherol
Diseases : Down Syndrome, Oxidative Stress
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation
Additional Keywords : Supplementation
[+]

A combination of high-dose vitamin D3 and ketogenic diet leads to changes in some biological markers of breast cancer.Sep 30, 2015

Pubmed Data : Anticancer Res. 2015 Oct ;35(10):5525-32. PMID: 26408720
Article Published Date : Sep 30, 2015
Study Type : Human: Case Report
Additional Links
Substances : Vitamin D
Diseases : Breast Cancer
Therapeutic Actions : Dietary Modification: Low Carbohydrate/Ketogenic
Additional Keywords : Supplementation
[+]

10% pectin supplementation for one month in adult rats decreases body-fat content and ameliorates age-related insulin and leptin resistance.Jul 21, 2015

Pubmed Data : Mol Nutr Food Res. 2015 Jul 22. Epub 2015 Jul 22. PMID: 26201873
Article Published Date : Jul 21, 2015
Study Type : Animal Study
Additional Links
Substances : Pectin
Diseases : Insulin Resistance
Additional Keywords : Anti-Obesity Agents, Gene Expression Regulation, Supplementation
[+]

Adolescent choline supplementation can attenuate some of the behavioural deficits associated with early developmental alcohol exposure.Mar 31, 2016

Pubmed Data : Alcohol Clin Exp Res. 2016 Apr ;40(4):897-905. PMID: 27038598
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Choline
Diseases : Alcohol Toxicity , Fetal Alcoholism
Additional Keywords : Supplementation
[+]

Ascorbate supplementation hinders metastasis, tumor growth and inflammatory cytokine secretion as well as enhanced encapsulation of tumors elicited by melanoma and breast cancer.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Oncol. 2013 Jan ;42(1):55-64. Epub 2012 Nov 21. PMID: 23175106
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Breast Cancer, Breast Cancer: Metastatic, Breast Cancer: Triple Negative , Inflammation, Melanoma, Melanoma: Metastasis
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antioxidants, Antiproliferative , Apoptotic
Additional Keywords : Cytokine Modulation, Significant Treatment Outcome , Supplementation
[+]

Astaxantin supplementation was found to regulate housekeeping genes in mice.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Genom Data. 2016 Mar ;7:32-7. Epub 2015 Nov 7. PMID: 26981356
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Gene Expression Regulation, Supplementation
[+]

Drinking green tea may reduce the toxic potential of acute high oral doses of EGCG supplementation. Jan 31, 2015

Pubmed Data : Food Chem Toxicol. 2015 Feb ;76:103-8. Epub 2014 Dec 17. PMID: 25528115
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate), Green Tea
Pharmacological Actions : Hepatoprotective
Additional Keywords : Bioavailability, Natural Substance Synergy, Supplementation
[+]

Fruits of A. carambola are useful as a dietary supplement in regulation of fluoride induced hyperglycemia, hyperlipemia and oxidative stress.May 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Interdiscip Toxicol. 2014 Jun ;7(2):103-10. Epub 2014 Nov 15. PMID: 26109886
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Star Fruit
Diseases : Fluoride Toxicity , Hyperglycemia, Hyperlipidemia, Oxidative Stress
Pharmacological Actions : Antioxidants, Hypoglycemic Agents, Hypolipidemic
Additional Keywords : Supplementation
Problem Substances : Sodium Fluoride
[+]

Melatonin loss in aging could be recompensed through dietary supplementation as a beneficial therapeutic strategy for AD prevention and progression.Apr 07, 2016

Pubmed Data : Neurosci Lett. 2016 Apr 8. Epub 2016 Apr 8. PMID: 27068758
Article Published Date : Apr 07, 2016
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Supplementation
[+]

Mitochondrial parameters including, SDA, ATP levels, MMP and MPP were reduced with statin treatment and improved by co-administration with CoQ10.May 21, 2015

Pubmed Data : Eur J Pharmacol. 2015 May 22 ;762:270-274. Epub 2015 May 22. PMID: 26007644
Article Published Date : May 21, 2015
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Drug-Induced Nutrient Depletion: Statin Drugs
Pharmacological Actions : Hepatoprotective
Additional Keywords : Supplementation
Problem Substances : Statin Drugs
[+]

Oral administration of magnesium-L-threonate reduces neuroinflammation.Nov 08, 2015

Pubmed Data : Cell Mol Immunol. 2015 Nov 9. Epub 2015 Nov 9. PMID: 26549801
Article Published Date : Nov 08, 2015
Study Type : In Vitro Study, Transgenic Animal Study
Additional Links
Substances : Magnesium
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
Additional Keywords : Supplementation
[+]

Pomegranate could be used as a supplement to enhance longevity, fertility and growth rate for the other living organisms and human beings.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Mag. 2015 Apr-Jun;11(42):356-9. PMID: 25829775
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Pomegranate
Diseases : Infertility
Pharmacological Actions : Antioxidants, Fertility Agents
Additional Keywords : Dose Response, Supplementation
[+]

Quercetin supplementation positively affected several aspects of cachexia progression in miceMay 31, 2014

Pubmed Data : J Nutr. 2014 Jun ;144(6):868-75. Epub 2014 Apr 23. PMID: 24759931
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Cachexia
Pharmacological Actions : Interleukin-6 Downregulation
Additional Keywords : Disease Progression, Supplementation
[+]

Supplementation with probiotics was able to reduce tumor incidence, tumor multiplicity and average tumor size.Apr 30, 2015

Pubmed Data : Nutr Cancer. 2015 May-Jun;67(4):603-11. Epub 2015 Mar 26. PMID: 25811420
Article Published Date : Apr 30, 2015
Study Type : Animal Study
Additional Links
Substances : Lactobacillus rhamnosus , Probiotics
Diseases : Colon Cancer, Colon Cancer: Prevention
Pharmacological Actions : Anticarcinogenic Agents, Antiproliferative , Cyclooxygenase 2 Inhibitors
Additional Keywords : Supplementation
[+]

Supplementation with β-cryptoxanthin would be beneficial for prophylaxis and for therapy of metabolic bone diseases associated with abnormal osteoclast activation.Aug 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacol Sci. 2015 Sep ;129(1):72-7. Epub 2015 Aug 22. PMID: 26342276
Article Published Date : Aug 31, 2015
Study Type : Animal Study
Additional Links
Substances : Cryptoxanthin
Diseases : Bone Diseases, Bone Diseases: Over-Active Osteoclasts
Additional Keywords : Supplementation
[+]

The addition of M. oleifera to diet afforded significant protection against nickel-induced nephrotoxicity.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr Metab. 2014 ;2014:958621. Epub 2014 Sep 11. PMID: 25295181
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Nickel Poisoning
Pharmacological Actions : Renoprotective
Additional Keywords : Supplementation
[+]

The iron from spinach and meats was more bioavailable than from supplements in this study. Feb 28, 1989

Pubmed Data : Br J Nutr. 1989 Mar ;61(2):331-43. PMID: 2640540
Article Published Date : Feb 28, 1989
Study Type : Animal Study
Additional Links
Substances : Spinach
Diseases : Anemia: Iron Deficiency
Additional Keywords : Bioavailability, Dietary Modification, Supplementation
[+]

The significant radioprotective effect of vitamin C at doses used in this study opens new horizons in developing non-toxic, cost effective, easily available radioprotectors.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Biomed Phys Eng. 2015 Jun ;5(2):59-66. Epub 2015 Jun 1. PMID: 26157731
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Vitamin A, Vitamin C, Vitamin E
Diseases : Radiotherapy
Pharmacological Actions : Radioprotective
Additional Keywords : Supplementation
[+]

Vitamin D prevents articular cartilage erosion by regulating collagen II turnover through TGF-β1 in ovariectomized rats.Sep 02, 2015

Pubmed Data : Osteoarthritis Cartilage. 2015 Sep 3. Epub 2015 Sep 3. PMID: 26343586
Article Published Date : Sep 02, 2015
Study Type : Animal Study
Additional Links
Substances : Vitamin D
Diseases : Arthritis, Vitamin D Deficiency
Additional Keywords : Dose Response, Supplementation
[+]

Folate deficiency-triggered redox pathways confering drug resistance in hepatocellular carcinoma.Jun 26, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2015 Jun 27. Epub 2015 Jun 27. PMID: 26327128
Article Published Date : Jun 26, 2015
Study Type : In Vitro Study
Additional Links
Substances : Folate
Diseases : Folic Acid/Folate Deficiency, Liver Cancer, Oxidative Stress
Additional Keywords : Multidrug Resistance, Supplementation
[+]

In this study supplementation with vitamin D led to improvements in muscle strength ranging from 1.37% to 18.75%.Jun 27, 2016

Pubmed Data : J Strength Cond Res. 2016 Jun 28. Epub 2016 Jun 28. PMID: 27379960
Article Published Date : Jun 27, 2016
Study Type : Review
Additional Links
Substances : Vitamin D
Diseases : Athletic Performance: Strength
Additional Keywords : Supplementation
[+]

Oral magnesium supplements appear to be useful in persons with DM2 to restore Mg deficiencies, to improve insulin resistance, oxidative stress, and systemic inflammation.Aug 24, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Diabetes. 2015 Aug 25 ;6(10):1152-7. PMID: 26322160
Article Published Date : Aug 24, 2015
Study Type : Review
Additional Links
Substances : Magnesium
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 2, Diabetes Mellitus: Type 2: Prevention, Insulin Resistance, Magnesium Deficiency
Additional Keywords : Supplementation
[+]

This review shows the enhancing effects of bioenhancers of drugs, nutrients and vitamins in animals and humans.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : ScientificWorldJournal. 2012 ;2012:637953. Epub 2012 Sep 17. PMID: 23028251
Article Published Date : Dec 31, 2011
Study Type : Review
Additional Links
Substances : Allicin, Aloe Vera, Capsaicin, Citrus naringin, Curcumin, Genistein, Glycyrrhizin, Piperine, Quercetin
Additional Keywords : Drug Interaction, Natural Substance/Drug Synergy, Supplementation
[+]

Vitamin B12 deficiency causes movement disorders in adults and in infants.May 21, 2014

Pubmed Data : Neurol Res. 2014 May 22:1743132814Y0000000396. Epub 2014 May 22. PMID: 24852503
Article Published Date : May 21, 2014
Study Type : Review
Additional Links
Substances : Vitamin B-12
Diseases : Movement Disorders, Neurological Conditions, Vitamin B 12 Deficiency
Additional Keywords : Involuntary Movements, Supplementation
[+]

Vitamin supplementation shows promise for the treatment of migraines with aura and menstrual induced migraines.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015;2015:469529. Epub 2015 Feb 28. PMID: 25815319
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Substances : Folic Acid , Riboflavin (Vitamin B-2), Vitamin B12, Vitamin B-6, Vitamin C, Vitamin E
Diseases : Menstrual Migraine, Migraine: Menstrual Cycle Induced, Migraine Disorders
Additional Keywords : Supplementation

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