Synergy with Tamoxifen

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1 Problem Substances Researched for Synergy with Tamoxifen

Name	AC	CK	Focus
Tamoxifen	1	2

7 Diseases Researched for Synergy with Tamoxifen

Name	AC	CK
Breast Cancer	24	29
Cancers: Drug Resistant	2	3
Breast Cancer: estrogen receptor alpha-positive	1	2
Breast Cancer: Triple Negative	1	1
Chemotherapy-Induced Toxicity: Tamoxifen	1	1
Endometrial Cancer	1	1
Liver Cancer	1	1

31 Substances Researched for Synergy with Tamoxifen

Name	AC	CK
Flaxseed	3	4
Paeoniflorin	3	3
Carnosic Acid	1	2
Curcumin	2	2
Huaier (Trametes robiniophila murr)	1	2
MSM (Methylsulfonylmethane)	1	2
Resveratrol	1	2
Shikonin	1	2
Aloe Vera	1	1
Bee Venom	1	1
Berberine	1	1
Caffeic acid phenethyl ester	1	1
Celastrol	1	1
EGCG (Epigallocatechin gallate)	1	1
Emodin	1	1
Evening Primrose Oil	1	1
Genistein	1	1
Glycyrrhizin	1	1
Green Tea	1	1
Hesperidin	1	1
Honey	1	1
Isoflavones	1	1
Kaempferol	1	1
Melatonin	1	1
Myricetin	1	1
Naringenin	1	1
Piperine	1	1
Quercetin	1	1
Red Clover	1	1
Rhubarb	1	1
Silibinin	1	1

20 Pharmacological Actions Researched for Synergy with Tamoxifen

Name	AC	CK
Apoptotic	8	11
Chemosensitizer	9	10
Antiproliferative	6	7
Anti-metastatic	2	4
Antineoplastic Agents	3	3
Autophagy Up-regulation	2	3
Bcl-2 protein down-regulation	2	3
Cell cycle arrest	2	3
Bcl-xL down-regulation	1	2
Chemotherapeutic	2	2
Anti-Angiogenic	1	1
Chemopreventive	1	1
Chemoprotective Agents	1	1
DNA Repair Up-regulation	1	1
Genoprotective	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1
Matrix metalloproteinase-9 (MMP-9) inhibitor	1	1
MicroRNA modulator	1	1
Multidrug Resistance Gene Modulators	1	1
Vascular Endothelial Growth Factor Inhibitors	1	1

Research Articles 27
Cumulative Knowledge Score 43
Overall Research Rating GOOD

View the Evidence:
27 Abstracts with Synergy with Tamoxifen Research

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View the Evidence: 27 Abstracts with Synergy with Tamoxifen Research

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Carnosic acid cooperates with tamoxifen to induce apoptosis in breast cancer cells.Apr 30, 2017

Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer in mice. Aug 01, 2001

Functional combination of resveratrol and tamoxifen to overcome tamoxifen-resistance in breast cancer cells.Jun 28, 2024

Huaier extract synergizes with tamoxifen to induce autophagy and apoptosis in ER-positive breast cancer cells.Mar 22, 2016

Methylsulfonylmethane and tamoxifen synergistically inhibits tumor growth and metastasis in ER-positive breast cancer xenografts.Jun 18, 2015

Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells.Dec 31, 2019

Aloe-emodin enhances tamoxifen cytotoxicity in breast cancer cells.Feb 22, 2017

Caffeic acid phenethyl ester augmented tamoxifen cytotoxicity via multiple mechanisms.Dec 31, 2015

Celastrol enhances tamoxifen sensitivity in the treatment of triple negative breast cancer.Dec 31, 2022

Co-treatment of tamoxifen and naringenin could inhibit cell proliferation more effectively in ER+ breast cancer cells.Aug 24, 2018

Co-treatment of the cells with melatonin loaded nanoparticles and tamoxifen caused two fold increase in the percentage of apoptosis.Apr 21, 2016

Enhancement of sensitivity to tamoxifen by berberine in breast cancer cells.Nov 30, 2022

Evening primrose oil enhances tamoxifen's anticancer activity against breast cancer cells.Apr 06, 2022

Flaxseed inhibits estrogen-dependent breast cancer cell growth and acts synergistically with Tamoxifen. Sep 01, 2007

Genistein and tamoxifen can significantly inhibit growth of liver cancer cells and plays a significant role in apoptosis.Jan 26, 2017

Hesperidin, piperine and bee venom synergistically potentiate the anticancer effect of tamoxifen against breast cancer cells.Aug 31, 2018

Interactions between natural products and tamoxifen in breast cancer.Dec 31, 2021

MDM2 is a Potential Target Gene of glycyrrhizic acid for circumventing breast cancer resistance to tamoxifen.Jun 30, 2022

Paeoniflorin enhances the sensitivity of ER-positive breast cancer cells to tamoxifen.Dec 31, 2021

Paeoniflorin has potential to be used as a co-treatment for circumventing breast cancer resistance to tamoxifen.Nov 30, 2021

Paeoniflorin sensitizes breast cancer cells to tamoxifen.Dec 31, 2020

Red clover as a dietary supplement can be beneficial for some patients with breast cancer who receive conventional chemotherapy.Dec 31, 2018

Some clinical trials showed that flaxseed can have an important role in decreasing breast cancer risk.Dec 31, 2017

Synergistic effect of curcumin and tamoxifen loaded in pH-responsive gemini surfactant nanoparticles on breast cancer cells.Sep 19, 2024

The combination of green tea and tamoxifen is more potent than either agent alone in suppressing breast cancer growth. Dec 01, 2006

The combinatory effects of glabridin and tamoxifen on Ishikawa and MCF-7 cell lines.Aug 31, 2015

Tualang honey enhances tamoxifen induced cytotoxicity and DNA damage in breast cancer cells while affording protection to the non-cancerous cells.Dec 31, 2013

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Synergy with Tamoxifen

View the Evidence:
27 Abstracts with Synergy with Tamoxifen Research