Tamoxifen Resistance

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3 Diseases Researched for Tamoxifen Resistance

Name	AC	CK
Breast Cancer	3	3
Cancers: Drug Resistant	2	2
Cancer Metastasis	1	1

2 Substances Researched for Tamoxifen Resistance

Name	AC	CK	Focus
Catechin	2	2
EGCG (Epigallocatechin gallate)	1	1

7 Pharmacological Actions Researched for Tamoxifen Resistance

Name	AC	CK
Anticarcinogenic Agents	1	1
Antiproliferative	1	1
Chemosensitizer	1	1
Drug synergy	1	1
Epidermal growth factor receptor (EGFR) inhibitor	1	1
Estrogen Receptor Modulators	1	1
Matrix metalloproteinase-2 (MMP-2) inhibitor	1	1

Research Articles 3
Cumulative Knowledge Score 4
Overall Research Rating GOOD

View the Evidence:
10 Abstracts with Tamoxifen Resistance Research

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[+]

Leptin attenuates the anti-estrogen effect of tamoxifen in breast cancer.Nov 14, 2012

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Pubmed Data : Biomed Pharmacother. 2012 Nov 15. Epub 2012 Nov 15. PMID: 23199901

Article Published Date : Nov 14, 2012

Study Type : Human In Vitro

Additional Links

Diseases : Leptin: Elevated Levels, Leptin Resistance

Additional Keywords : Tamoxifen Resistance

Problem Substances : Leptin: Elevated Levels

[+]

"Curcumin Induces Cell Death and Restores Tamoxifen Sensitivity in the Antiestrogen-Resistant Breast Cancer Cell Lines MCF-7/LCC2 and MCF-7/LCC9."Dec 31, 2012

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Pubmed Data : Molecules. 2013 ;18(1):701-20. Epub 2013 Jan 8. PMID: 23299550

Article Published Date : Dec 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Curcumin

Diseases : Breast Cancer: Drug Resistant

Pharmacological Actions : Chemosensitizer

Additional Keywords : Tamoxifen Resistance

[+]

An extract of vitex negundo inhibits cell growth and induces programmed cell death in tamoxifen-resistance human breast cancer cells.Aug 31, 2012

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Pubmed Data : Zhejiang Da Xue Xue Bao Yi Xue Ban. 2012 Sep ;41(5):498-505. PMID: 23086641

Article Published Date : Aug 31, 2012

Study Type : In Vitro Study

Additional Links

Substances : Vitex negundo

Pharmacological Actions : Antiproliferative , Apoptotic, Chemosensitizer

Additional Keywords : Tamoxifen Resistance

[+]

Black tea polyphenol inhibits aromatase activity and attenuates tamoxifen resistance in HER2/neu transfected human breast cancer cells. Sep 01, 2004

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Pubmed Data : Eur J Cancer. 2004 Sep;40(14):2165-74. PMID: 15341993

Article Published Date : Sep 01, 2004

Study Type : In Vitro Study

Additional Links

Substances : Black Tea

Diseases : Breast Cancer

Additional Keywords : HER2/neu, Tamoxifen Resistance

[+]

EGCG exhibits anti-cancer activity against tamoxifen-resistant breast cancer lines.Apr 01, 2011

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Pubmed Data : Biosci Rep. 2011 Apr ;31(2):99-108. PMID: 20446926

Article Published Date : Apr 01, 2011

Study Type : In Vitro Study

Additional Links

Substances : Catechin

Diseases : Breast Cancer, Cancer Metastasis, Cancers: Drug Resistant

Pharmacological Actions : Antiproliferative , Epidermal growth factor receptor (EGFR) inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor

Additional Keywords : Drug: Tamoxifen, Tamoxifen Resistance

[+]

EGCG is capable of killing tamoxifen-resistant breast cancer cells.Jan 01, 2007

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Pubmed Data : Cancer Detect Prev. 2007 ;31(6):499-504. PMID: 18061364

Article Published Date : Jan 01, 2007

Study Type : In Vitro Study

Additional Links

Substances : Catechin

Diseases : Breast Cancer

Pharmacological Actions : Anticarcinogenic Agents, Estrogen Receptor Modulators

Additional Keywords : Drug: Tamoxifen, Tamoxifen Resistance

[+]

EGCG may act as a chemosensitizing agent in tamoxifen-resistant breast cancer cells. Jun 27, 2002

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Pubmed Data : Mutat Res. 2002 Jun 27;518(1):71-84. PMID: 20149610

Article Published Date : Jun 27, 2002

Study Type : In Vitro Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Breast Cancer, Cancers: Drug Resistant

Pharmacological Actions : Chemosensitizer, Drug synergy

Additional Keywords : Tamoxifen Resistance

[+]

EPA may be useful for the treatment of tamoxifen-resistant breast cancer cells with high levels of activated Akt .Jun 30, 2003

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Pubmed Data : Ann Oncol. 2003 Jul ;14(7):1051-6. PMID: 12853346

Article Published Date : Jun 30, 2003

Study Type : In Vitro Study

Additional Links

Substances : EPA (Eicosapentaenoic Acid)

Diseases : Breast Cancer, Cancers: Drug Resistant

Additional Keywords : Drug: Tamoxifen, Tamoxifen Resistance

Problem Substances : Tamoxifen

[+]

Quercetin Inhibits angiogenesis in tamoxifen-resistant breast cancer cells.Oct 31, 2010

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Pubmed Data : Food Chem Toxicol. 2010 Nov ;48(11):3227-34. Epub 2010 Sep 4. PMID: 20804812

Article Published Date : Oct 31, 2010

Study Type : In Vitro Study

Additional Links

Substances : Quercetin

Diseases : Breast Cancer, Cancers: Drug Resistant

Pharmacological Actions : Anti-Angiogenic, Antioxidants, Vascular Endothelial Growth Factor A Inhibitor

Additional Keywords : Drug: Tamoxifen, Tamoxifen Resistance

Problem Substances : Tamoxifen

[+]

Resveratrol exhibits anti-cancer properties against tamoxifen-resistant breast cancer cells.Sep 30, 2011

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : FASEB J. 2011 Oct ;25(10):3695-707. Epub 2011 Jul 7. PMID: 21737614

Article Published Date : Sep 30, 2011

Study Type : In Vitro Study

Additional Links

Substances : Resveratrol

Diseases : Breast Cancer: Drug Resistant

Pharmacological Actions : Estrogen Receptor Modulators, Tumor Suppressor Protein p53 Upregulation

Additional Keywords : Tamoxifen Resistance

Problem Substances : Tamoxifen

Tamoxifen Resistance Related Articles

Tamoxifen: Praised As "Life Saving" But Still Causing Cancer

Written by Sayer Ji, Founder

Many of the drugs used to treat breast cancer today are probable or known cancer-causing agents. Tamoxifen, for instance, is classified by the World Health Organization as a "human carcinogen," but recent news headlines praised extended use of this drug for "saving lives." It is obvious that the mainstream media has swallowed the tamoxifen-flavored Kool-Aid ... will you?

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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Focus Your Research

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View the Evidence: 10 Abstracts with Tamoxifen Resistance Research

Limited to Members Only

Currently Available Sorting Options

Leptin attenuates the anti-estrogen effect of tamoxifen in breast cancer.Nov 14, 2012

"Curcumin Induces Cell Death and Restores Tamoxifen Sensitivity in the Antiestrogen-Resistant Breast Cancer Cell Lines MCF-7/LCC2 and MCF-7/LCC9."Dec 31, 2012

An extract of vitex negundo inhibits cell growth and induces programmed cell death in tamoxifen-resistance human breast cancer cells.Aug 31, 2012

Black tea polyphenol inhibits aromatase activity and attenuates tamoxifen resistance in HER2/neu transfected human breast cancer cells. Sep 01, 2004

EGCG exhibits anti-cancer activity against tamoxifen-resistant breast cancer lines.Apr 01, 2011

EGCG is capable of killing tamoxifen-resistant breast cancer cells.Jan 01, 2007

EGCG may act as a chemosensitizing agent in tamoxifen-resistant breast cancer cells. Jun 27, 2002

EPA may be useful for the treatment of tamoxifen-resistant breast cancer cells with high levels of activated Akt .Jun 30, 2003

Quercetin Inhibits angiogenesis in tamoxifen-resistant breast cancer cells.Oct 31, 2010

Resveratrol exhibits anti-cancer properties against tamoxifen-resistant breast cancer cells.Sep 30, 2011

Tamoxifen Resistance Related Articles

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Tamoxifen Resistance

View the Evidence:
10 Abstracts with Tamoxifen Resistance Research