Wrinkles

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4 Diseases Researched for Wrinkles
NameACCKFocus
Wrinkles22196Locked
Aging Skin19161Locked
Ultraviolet Radiation Induced Damage212Locked
Skin Diseases: Photo-Aging110Locked
21 Substances Researched for Wrinkles
NameACCKFocus
Almond220Locked
Gotu Kola120Locked
Cocoa418Locked
Mushrooms: All 115Locked
Aloe Vera110Locked
Amla Fruit110Locked
Chicken extract110Locked
Dates110Locked
Fig110Locked
Fish Oil110Locked
Flavonoids110Locked
Ginkgo biloba110Locked
Hydrangea110Locked
Lingonberry110Locked
Orange: Mandarin110Locked
Pomegranate110Locked
Rose 110Locked
Rutin110Locked
White Mulberry 110Locked
Phlorotannins12Locked
Ginseng11Locked
2 Therapeutic Actions Researched for Wrinkles
NameACCKFocus
Light Therapy: Red Colored110Locked
Sunlight exposure12Locked
10 Pharmacological Actions Researched for Wrinkles
NameACCKFocus
Photoprotective530Locked
Antioxidants422Locked
Matrix metalloproteinase-1 (MMP-1) inhibitor220Locked
Anti-Apoptotic110Locked
Anti-collagenase110Locked
MicroRNA modulator110Locked
Enzyme Inhibitors11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor11Locked
Tyrosinase Inhibition11Locked

View the Evidence:
25 Abstracts with Wrinkles Research

[+]

Efficacy and safety of Centella Asiatica on wrinkles.Oct 31, 2020

Pubmed Data : J Cosmet Sci. 2020 Nov-Dec;71(6):439-454. PMID: 33413787
Article Published Date : Oct 31, 2020
Study Type : Meta Analysis, Review
Additional Links
Substances : Gotu Kola
Diseases : Wrinkles
[+]

A study of facial wrinkles improvement effect of veratric acid from cauliflower mushroom.Mar 31, 2016

Pubmed Data : Arch Dermatol Res. 2016 Apr ;308(3):183-92. Epub 2016 Feb 25. PMID: 26914455
Article Published Date : Mar 31, 2016
Study Type : Human In Vitro, Human Study
Additional Links
Substances : Mushrooms: All
Diseases : Aging Skin, Wrinkles
Pharmacological Actions : Photoprotective
[+]

Aloe gel significantly improves wrinkles and elasticity in photoaged human skin.Feb 01, 2009

Pubmed Data : Ann Dermatol. 2009 Feb;21(1):6-11. Epub 2009 Feb 28. PMID: 20548848
Article Published Date : Feb 01, 2009
Study Type : Human Study
Additional Links
Substances : Aloe Vera
Diseases : Aging Skin, Skin Diseases: Photo-Aging, Wrinkles
Pharmacological Actions : Matrix metalloproteinase-1 (MMP-1) inhibitor
[+]

Anti-wrinkle and skin moisture efficacy of 7-MEGA.Jan 08, 2024

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2024 Jan 9 ;16(2). Epub 2024 Jan 9. PMID: 38257104
Article Published Date : Jan 08, 2024
Study Type : Human Study
Additional Links
Substances : Fish Oil
Diseases : Aging Skin, Wrinkles
[+]

Assessment of the effect of extract formulation of date palm kernel on facial skin wrinkles.Dec 31, 2018

Pubmed Data : J Cosmet Sci. 2019 Nov/Dec;70(6):277-290. PMID: 31829921
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Substances : Dates
Diseases : Aging Skin, Wrinkles
Additional Keywords : Plant Extracts
[+]

Biological effects of rutin on skin aging.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2016 Jul ;38(1):357-63. Epub 2016 May 24. PMID: 27220601
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Substances : Rutin
Diseases : Aging Skin, Wrinkles
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Matrix metalloproteinase-1 (MMP-1) inhibitor, MicroRNA modulator
[+]

Daily almond consumption may reduce wrinkle severity in postmenopausal females to potentially have natural anti-aging benefits.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2019 Oct 1. Epub 2019 Oct 1. PMID: 31576607
Article Published Date : Sep 30, 2019
Study Type : Human Study
Additional Links
Substances : Almond
Diseases : Aging Skin, Wrinkles
[+]

Green mandarins effectively improves UV-induced skin wrinkles.Mar 23, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2022 Mar 24 ;14(7). Epub 2022 Mar 24. PMID: 35405965
Article Published Date : Mar 23, 2022
Study Type : Human Study
Additional Links
Substances : Orange: Mandarin
Diseases : Aging Skin, Ultraviolet Radiation Induced Damage, Wrinkles
Pharmacological Actions : Photoprotective
Additional Keywords : Plant Extracts
[+]

Hot water extract of Hydrangea serrata leaves could be used as a health supplement for skin anti-aging.May 27, 2020

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2020 May 28 ;12(6). Epub 2020 May 28. PMID: 32481760
Article Published Date : May 27, 2020
Study Type : Human Study
Additional Links
Substances : Hydrangea
Diseases : Aging Skin, Wrinkles
[+]

In moderately photo-aged women, regular cocoa flavanol consumption had positive effects on facial wrinkles and elasticity.Nov 17, 2015

Pubmed Data : J Nutr. 2015 Nov 18. Epub 2015 Nov 18. PMID: 26581682
Article Published Date : Nov 17, 2015
Study Type : Human Study
Additional Links
Substances : Cocoa
Diseases : Wrinkles
[+]

Low-level light therapy using 660 nm LEDs or 411 to 777 nm LEDs significantly improved periocular wrinkles.Feb 28, 2017

Pubmed Data : Dermatol Surg. 2017 Mar ;43(3):371-380. PMID: 28195844
Article Published Date : Feb 28, 2017
Study Type : Human Study
Additional Links
Diseases : Aging Skin, Wrinkles
Therapeutic Actions : Laser Treatment: Low-Level, Light Therapy: Red Colored
[+]

Male facial rejuvenation using a combination 633, 830, and 1072 nm LED face mask.Oct 31, 2023

Pubmed Data : Arch Dermatol Res. 2023 Nov ;315(9):2605-2611. Epub 2023 Jul 7. PMID: 37418018
Article Published Date : Oct 31, 2023
Study Type : Human Study
Additional Links
Diseases : Aging Skin, Wrinkles
Therapeutic Actions : Infrared Light, Light Therapy: Red Colored
[+]

Novel hydrolyzed chicken sternal cartilage extract improves facial epidermis and connective tissue in healthy adult females.Aug 31, 2019

Pubmed Data : Altern Ther Health Med. 2019 Sep ;25(5):12-29. PMID: 31221944
Article Published Date : Aug 31, 2019
Study Type : Human Study
Additional Links
Substances : Chicken extract
Diseases : Aging Skin, Wrinkles
[+]

Oral consumption of Bonito fish-derived elastin peptide (VGPG Elastin® ) improves biophysical properties in aging skin.Feb 29, 2024

Pubmed Data : Skin Res Technol. 2024 Mar ;30(3):e13634. PMID: 38481080
Article Published Date : Feb 29, 2024
Study Type : Human Study
Additional Links
Substances : Fish
Diseases : Aging Skin, Wrinkles
[+]

Oral intake of lingonberry and amla fruit extract improves skin conditions in healthy female subjects.Aug 31, 2019

Pubmed Data : Biotechnol Appl Biochem. 2019 Sep ;66(5):870-879. Epub 2019 Aug 16. PMID: 31342566
Article Published Date : Aug 31, 2019
Study Type : Human Study
Additional Links
Substances : Amla Fruit, Lingonberry
Diseases : Aging Skin, Wrinkles
Additional Keywords : Plant Extracts
[+]

Pycnogenol supplementation benefits human skin by increasing skin hydration and skin elasticity. Dec 31, 2011

Pubmed Data : Skin Pharmacol Physiol. 2012 ;25(2):86-92. Epub 2012 Jan 21. PMID: 22270036
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Substances : Flavonoids
Diseases : Aging Skin, Wrinkles
[+]

The combined formulation of fruit extracts showed excellent antioxidative and anti-collagenase activity as well as a significant effect on anti-wrinkle activity on human skin.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Cosmet Investig Dermatol. 2015 ;8:389-96. Epub 2015 Jul 16. PMID: 26203268
Article Published Date : Dec 31, 2014
Study Type : Human Study, In Vitro Study
Additional Links
Substances : Fig, Ginkgo biloba, Pomegranate, White Mulberry
Diseases : Aging Skin, Wrinkles
Pharmacological Actions : Anti-collagenase, Antioxidants
Additional Keywords : Dose Response, Natural Substances Versus Drugs, Plant Extracts
[+]

The daily consumption of almonds may improve several aspects of photoaging such as facial wrinkles and pigment intensity in postmenopausal women.Feb 26, 2021

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2021 Feb 27 ;13(3). Epub 2021 Feb 27. PMID: 33673587
Article Published Date : Feb 26, 2021
Study Type : Human Study
Additional Links
Substances : Almond
Diseases : Aging Skin, Wrinkles
[+]

The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Interv Aging. 2015 ;10:1849-56. Epub 2015 Nov 19. PMID: 26604725
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Rose
Diseases : Aging Skin, Wrinkles
[+]

The efficacy of red and near-infrared light treatment in patient satisfaction, reduction of fine lines, wrinkles, skin roughness, and intradermal collagen density increase.Jan 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Photomed Laser Surg. 2014 Feb ;32(2):93-100. Epub 2013 Nov 28. PMID: 24286286
Article Published Date : Jan 31, 2014
Study Type : Human Study
Additional Links
Diseases : Aging Skin, Wrinkles
Therapeutic Actions : Light Therapy: Red Colored
Additional Keywords : Skin Rejuvenation
[+]

Cocoa pod extracts help to reduce wrinkles on skin after 3 weeks of application.Apr 03, 2016

Pubmed Data : J Cosmet Dermatol. 2016 Apr 4. Epub 2016 Apr 4. PMID: 27041391
Article Published Date : Apr 03, 2016
Study Type : Human In Vitro
Additional Links
Substances : Cocoa
Diseases : Wrinkles
Additional Keywords : Plant Extracts
[+]

Cacao extract may offer a protective effects against photo-aging.Feb 04, 2016

Pubmed Data : J Invest Dermatol. 2016 Feb 5. Epub 2016 Feb 5. PMID: 26854493
Article Published Date : Feb 04, 2016
Study Type : Animal Study
Additional Links
Substances : Cocoa
Diseases : Aging Skin, Ultraviolet Radiation Induced Damage, Wrinkles
Pharmacological Actions : Photoprotective
Additional Keywords : Plant Extracts
[+]

Dieckol isolated from Eisenia bicyclis ameliorates wrinkling and improves skin hydration.Dec 13, 2022

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mar Drugs. 2022 Dec 14 ;20(12). Epub 2022 Dec 14. PMID: 36547926
Article Published Date : Dec 13, 2022
Study Type : Animal Study
Additional Links
Substances : Phlorotannins
Diseases : Aging Skin, Wrinkles
Therapeutic Actions : Sunlight exposure
Pharmacological Actions : Photoprotective
[+]

Anti‑wrinkle effect of fermented black ginseng on human fibroblasts.Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Med. 2017 Mar ;39(3):681-686. Epub 2017 Jan 16. PMID: 28098856
Article Published Date : Feb 28, 2017
Study Type : In Vitro Study
Additional Links
Substances : Ginseng
Diseases : Aging Skin, Wrinkles
Pharmacological Actions : Antioxidants, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords : Plant Extracts
[+]

Cocoa pod extract has high potential as a cosmetic ingredient due to its anti-wrinkle, skin whitening, and sunscreen effects.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2014 ;14:381. Epub 2014 Oct 7. PMID: 25292439
Article Published Date : Dec 31, 2013
Study Type : In Vitro Study
Additional Links
Substances : Cocoa
Diseases : Aging Skin, Wrinkles
Pharmacological Actions : Antioxidants, Enzyme Inhibitors, Photoprotective, Tyrosinase Inhibition
Additional Keywords : Plant Extracts

Wrinkles Related Articles

Fluoride in your Drinking Water Making You LOOK Older?
Written by Anne Gordon, RN
Fluoride in your Drinking Water Making You LOOK Older? In the 1950' a TV commercial convinced people that fluoride was outstanding for teeth. By brushing, yellow teeth would become white, and cavities would be eradicated. Dentists concurred and encouraged the use of fluoride. So, through clever marketing, it became an urban belief that fluoride in toothpaste would be fabulous for strong healthy cavity free white teeth.
Fluoride in your Drinking Water Making You LOOK Older?
Written by Anne Gordon, RN
Fluoride in your Drinking Water Making You LOOK Older? In the 1950' a TV commercial convinced people that fluoride was outstanding for teeth. By brushing, yellow teeth would become white, and cavities would be eradicated. Dentists concurred and encouraged the use of fluoride. So, through clever marketing, it became an urban belief that fluoride in toothpaste would be fabulous for strong healthy cavity free white teeth.
Five Natural Substances to Reduce Facial Wrinkles
Written by GreenMedInfo Research Group
Food feeds your skin, and this is clearly demonstrated by how a number of natural ingredients and herbal extracts can help reduce and prevent facial wrinkles. Here are five time-tested ways to say goodbye to those deep, unnerving wrinkles
Red and Amber Light Therapy: A New Dawn in Wrinkle Reduction
Written by GreenMedInfo Research Group
In the quest for youthful skin, a groundbreaking study has shed light on the potential of photobiomodulation therapy to turn back the clock on facial aging
Aging Skin: GreenMedInfo.com's Top 20 Longevity Promoting Substances
Written by GreenMedInfo Research Group
As concerns about accelerated skin aging continue to rise, groundbreaking research has unveiled the power of natural compounds to slow down and even reverse the visible signs of aging.
Revitalize Your Skin: The Power of Red Light Therapy in Reversing Premature Aging
Written by GreenMedInfo Research Group
Are you tired of empty promises from anti-aging creams and expensive treatments? Discover how red light therapy is revolutionizing skin care, providing a scientifically-backed, non-invasive path to visibly younger-looking skin
Revitalize Your Skin: The Power of Red Light Therapy in Reversing Premature Aging
Written by GreenMedInfo Research Group
Are you tired of empty promises from anti-aging creams and expensive treatments? Discover how red light therapy is revolutionizing skin care, providing a scientifically-backed, non-invasive path to visibly younger-looking skin
Research: A Tsp. of Aloe Daily Reverses Signs of Skin Aging
Written by Sayer Ji, Founder
There is plenty of research that indicates that the unnaturally accelerated aging process associated with modern living and/or natural environmental exposures such as excessive ultraviolet radiation (photo-aging), can be slowed.
Research: A Tsp. of Aloe Daily Reverses Signs of Skin Aging
Written by Sayer Ji, Founder
There is plenty of research that indicates that the unnaturally accelerated aging process associated with modern living and/or natural environmental exposures such as excessive ultraviolet radiation (photo-aging), can be slowed.
Red and Amber Light Therapy: A New Dawn in Wrinkle Reduction
Written by GreenMedInfo Research Group
In the quest for youthful skin, a groundbreaking study has shed light on the potential of photobiomodulation therapy to turn back the clock on facial aging
Aging Skin: GreenMedInfo.com's Top 20 Longevity Promoting Substances
Written by GreenMedInfo Research Group
As concerns about accelerated skin aging continue to rise, groundbreaking research has unveiled the power of natural compounds to slow down and even reverse the visible signs of aging.
Five Natural Substances to Reduce Facial Wrinkles
Written by GreenMedInfo Research Group
Food feeds your skin, and this is clearly demonstrated by how a number of natural ingredients and herbal extracts can help reduce and prevent facial wrinkles. Here are five time-tested ways to say goodbye to those deep, unnerving wrinkles

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