AMP-activated protein kinase modulation

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8 Substances Researched for AMP-activated protein kinase modulation
NameACCKFocus
Curcumin23Locked
Quercetin23Locked
Resveratrol23Locked
Bitter Melon12Locked
Catechin 12Locked
Berberine11Locked
EGCG (Epigallocatechin gallate)11Locked
Polyphenols11Locked

View the Evidence:
4 Abstracts with AMP-activated protein kinase modulation Research

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An isocaloric carbohydrate restriction diet and natural AMPK activating agents induce synergistic anticancer effects.Mar 18, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur J Cancer Prev. 2015 Mar 19. Epub 2015 Mar 19. PMID: 25747515
Article Published Date : Mar 18, 2015
Study Type : In Vitro Study, Transgenic Animal Study
Additional Links
Substances : Catechin , Curcumin, Quercetin, Resveratrol
Diseases : Liver Cancer, Melanoma
Therapeutic Actions : Dietary Modification: Low Carbohydrate
Pharmacological Actions : AMP-activated protein kinase modulation , Antiproliferative , Chemopreventive, Interleukin-6 Downregulation, SIRT1 Activator
Additional Keywords : Diet Induced Tumor Suppression
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Bitter melon extract functions as a natural AMPK activator in the inhibition of ovarian cancer cell growth and might be useful as a supplement to improve the efficacy of cisplatin.Oct 18, 2015

Pubmed Data : Integr Cancer Ther. 2015 Oct 19. Epub 2015 Oct 19. PMID: 26487740
Article Published Date : Oct 18, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Bitter Melon
Diseases : Ovarian Cancer
Pharmacological Actions : AMP-activated protein kinase modulation , Anticarcinogenic Agents
Additional Keywords : Chemotherapeutic Synergy: Cisplatin
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Curcumin's blood sugar lowering effect may be due to its inhibitory effect on hepatic gluconeogenesis. Oct 16, 2009

Pubmed Data : Biochem Biophys Res Commun. 2009 Oct 16;388(2):377-82. Epub 2009 Aug 8. PMID: 19665995
Article Published Date : Oct 16, 2009
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2
Pharmacological Actions : AMP-activated protein kinase modulation , Gluconeogenesis Inhibitor
Additional Keywords : Metformin Alternatives, Natural Substances Versus Drugs
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Polyphenols may have therapeutic value in a variety of diseases through modulating AMP-activated protein kinase which reduce fatty acid and cholesterol synthesis and gluconeogenesis. Oct 01, 2009

Pubmed Data : N Biotechnol.2009 Oct 1;26(1-2):17-22. Epub 2009 Apr 2. PMID: 19818314
Article Published Date : Oct 01, 2009
Study Type : Commentary
Additional Links
Substances : Berberine, EGCG (Epigallocatechin gallate), Polyphenols, Quercetin, Resveratrol
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2, Hypertension, Metabolic Syndrome X, Obesity
Pharmacological Actions : AMP-activated protein kinase modulation , Gluconeogenesis Inhibitor

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