Angiogenesis Inducing Agents

Name	AC	CK
Ginsenosides	9	16
Astragaloside	8	14
Ginkgo biloba	4	8
Crocin	2	7
Berberine	3	6
Fucoidan	4	6
Safflower	3	5
Salvia miltiorrhiza	3	5
Tanshinone IIA	3	5
Citrus naringin	2	4
Formononetin	2	4
Hesperidin	2	4
Panax Notoginseng	2	4
Sesamin	2	4
Baicalein	2	3
Chlorella (Algae)	1	3
Citicoline	2	3
Naringenin	1	3
Onion	1	3
Plantago	1	3
Shilajit	1	3
Allicin	1	2
Aloe Vera	1	2
Arginine	1	2
Astragalus	1	2
Celery Oil	1	2
Curcumin	1	2
Curcumol	1	2
Dogwood	1	2
Echinacea	1	2
Fermented Foods and Beverages	1	2
Garlic	1	2
Ginseng (Korean)	1	2
Honey	1	2
Hydrogen Water	1	2
Icariin	1	2
Magnesium	1	2
NAC (N-acetyl-L-cysteine)	1	2
Organosulfur Compounds	1	2
Paeoniflorin	1	2
Puerarin	1	2
Red Sage	1	2
Shikonin	1	2
Urolithin A	1	2
Verbena officinalis	1	2
Vitamin C	1	2
Vitamin D	1	2
Zerumbone	1	2
Beta Sitosterol	1	1
Flavonoids	1	1
Gastrodin	1	1
Geum japonicum	1	1
Hawthorn	1	1
Luteolin	1	1
Poria cocos	1	1
Propolis: Bee	1	1
Rhubarb	1	1

Diseases : Wound Healing

Pharmacological Actions : Angiogenesis Inducing Agents, Anti-Inflammatory Agents

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Pubmed Data : J Am Coll Nutr. 2019 Aug ;38(6):526-536. Epub 2019 Jun 4. PMID: 31161927

Article Published Date : Jul 31, 2019

Study Type : Human: Case Report

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Substances : Shilajit

Pharmacological Actions : Angiogenesis Inducing Agents

Additional Keywords : Gene Expression Regulation

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The ginsenoside Rg1 nanoparticles may be an available blood-brain barrier penetrating agent for ischemic stroke.Dec 31, 2021

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Pubmed Data : Int J Nanomedicine. 2022 ;17:5447-5468. Epub 2022 Nov 18. PMID: 36426373

Article Published Date : Dec 31, 2021

Study Type : Animal Study, In Vitro Study

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Substances : Ginsenosides

Diseases : Stroke: Ischemic

Pharmacological Actions : Angiogenesis Inducing Agents, Neuroprotective Agents

Additional Keywords : Blood Brain Barrier

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Unlocking the power of onion peel extracts: antimicrobial and anti-inflammatory effects improve wound healing.Sep 27, 2023

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Pubmed Data : Pharmaceuticals (Basel). 2023 Sep 28 ;16(10). Epub 2023 Sep 28. PMID: 37895850

Article Published Date : Sep 27, 2023

Study Type : Animal Study, In Vitro Study

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Substances : Onion

Diseases : Wound Healing

Pharmacological Actions : Angiogenesis Inducing Agents, Anti-Inflammatory Agents, Antimicrobial

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1,25(OH)2D3 improves diabetic wound healing by modulating inflammation and promoting angiogenesis.Feb 07, 2024

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Pubmed Data : J Steroid Biochem Mol Biol. 2024 Feb 8:106477. Epub 2024 Feb 8. PMID: 38340904

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Pubmed Data : Circ J. 2006 Apr ;70(4):463-70. PMID: 16565566

Article Published Date : Mar 31, 2006

Study Type : Animal Study

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Diseases : Ischemia

Therapeutic Actions : Thermal Therapy: Far-Infrared

Pharmacological Actions : Angiogenesis Inducing Agents, Nitric Oxide Enhancer

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Angiogenic function of astragaloside IV in rats with myocardial infarction occurs via the PKD1-HDAC5-VEGF pathway.Mar 31, 2019

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Pubmed Data : J Nutr Metab. 2016 ;2016:3703216. Epub 2016 Dec 5. PMID: 28050282

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Pubmed Data : Invest Ophthalmol Vis Sci. 2011 Jan 21 ;52(1):427-33. Epub 2011 Jan 21. PMID: 20847117

Article Published Date : Jan 20, 2011

Study Type : Animal Study

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Substances : Hydrogen Water, NAC (N-acetyl-L-cysteine)

Diseases : Burns, Eye Damage, Oxidative Stress

Pharmacological Actions : Angiogenesis Inducing Agents, Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor

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Icariin accelerates bone regeneration by inducing osteogenesis-angiogenesis coupling in rats with type 1 diabetes mellitus.Apr 14, 2024

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Pubmed Data : World J Diabetes. 2024 Apr 15 ;15(4):769-782. PMID: 38680705

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Potential use of tailored citicoline chitosan-coated liposomes for effective wound healing in diabetes.Dec 31, 2021

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Sesamin promotes angiogenesis and accelerates wound healing.Jan 20, 2020

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Pubmed Data : Biosci Biotechnol Biochem. 2020 Jan 21:1-11. Epub 2020 Jan 21. PMID: 31964241

Article Published Date : Jan 20, 2020

Study Type : Animal Study, In Vitro Study

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Substances : Sesamin

Diseases : Wound Healing

Pharmacological Actions : Angiogenesis Inducing Agents

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Sesamin promotes osteoporotic fracture healing by activating chondrogenesis and angiogenesis pathways.May 17, 2022

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Pubmed Data : Biomedicines. 2021 Mar 9 ;9(3). Epub 2021 Mar 9. PMID: 33803396

Article Published Date : Mar 08, 2021

Study Type : Review

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Diseases : Endothelial Dysfunction, Restenosis

Therapeutic Actions : Infrared Light, Photobiomodulation

Pharmacological Actions : Angiogenesis Inducing Agents, Anti-Inflammatory Agents, Vasodilator Agents

Additional Keywords : Risk Reduction

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Pubmed Data : Curr Neurovasc Res. 2021 Nov 8. Epub 2021 Nov 8. PMID: 34751117

Article Published Date : Nov 07, 2021

Study Type : In Vitro Study

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Substances : Safflower

Diseases : Brain Ischemia

Pharmacological Actions : Angiogenesis Inducing Agents

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Implantation of low-level laser irradiated mesenchymal stem cells into the infarcted rat heart is associated with reduction in infarct size and enhanced angiogenesis.Mar 31, 2009

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Pubmed Data : Photomed Laser Surg. 2009 Apr ;27(2):227-33. PMID: 19382832

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Pubmed Data : Bioact Mater. 2023 Jan ;19:24-37. Epub 2022 Apr 1. PMID: 35415312

Article Published Date : Dec 31, 2022

Study Type : In Vitro Study

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Substances : Gastrodin

Pharmacological Actions : Angiogenesis Inducing Agents, Anti-Inflammatory Agents, Immunomodulatory, Osteogenic

Additional Keywords : Bone Regeneration

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Oroxylin a attenuates limb ischemia by promoting angiogenesis.Dec 31, 2020

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Pubmed Data : Exp Ther Med. 2018 Feb ;15(2):1847-1854. Epub 2017 Dec 15. PMID: 29434774

Article Published Date : Jan 31, 2018

Study Type : In Vitro Study

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Substances : Astragaloside, Tanshinone IIA

Diseases : Coronary Artery Disease

Pharmacological Actions : Angiogenesis Inducing Agents

Additional Keywords : Mesenchymal Stem Cells

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The dual actions of angiogenesis and anti-apoptosis induced by an isolated fraction from Geum japonicum repair muscle ischemia.Feb 28, 2007

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Pubmed Data : Arch Biochem Biophys. 2007 Mar 1 ;459(1):91-7. Epub 2006 Nov 7. PMID: 17188640

View the Evidence: 127 Abstracts with Angiogenesis Inducing Agents Research

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Hyperbaric oxygen can induce angiogenesis and recover erectile function.May 17, 2018

Hyperbaric oxygen therapy in management of diabetic foot ulcers.Dec 31, 2020

Crocin improves lower extremity deep venous thrombosis.Sep 29, 2023

Astragaloside IV induces the protective effect of bone marrow mesenchymal stem cells derived exosomes in acute myocardial infarction.Mar 26, 2023

Chlorella sp.-ameliorated undesirable microenvironment promotes diabetic wound healing.Dec 31, 2022

Healing effect of carboxymethyl chitosan-plantamajoside hydrogel on burn wound skin.May 31, 2022

Increased dermal angiogenesis after low-intensity laser therapy for a chronic radiation ulcer determined by a video measuring system.Feb 28, 1999

Naringenin promotes angiogenesis of ischemic myocardium after myocardial infarction.Nov 30, 2022

Notoginsenoside R1 facilitates cell angiogenesis by inactivating the Notch signaling during wound healing.Mar 10, 2023

Photobiomodulation (PBM) promotes angiogenesis in-vitro and in chick embryo chorioallantoic membrane model.Nov 19, 2018

Supplemented with natural herbo-mineral Shilajit shows induction of microvascular and extracellular matrix mechanisms.Jul 31, 2019

The ginsenoside Rg1 nanoparticles may be an available blood-brain barrier penetrating agent for ischemic stroke.Dec 31, 2021

Unlocking the power of onion peel extracts: antimicrobial and anti-inflammatory effects improve wound healing.Sep 27, 2023

1,25(OH)2D3 improves diabetic wound healing by modulating inflammation and promoting angiogenesis.Feb 07, 2024

2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside treatment promoted angiogenesis and recovery from ischemia/reperfusion-induced brain injury.Apr 30, 2017

Allicin protects against myocardial I/R by accelerating angiogenesis via the miR-19a-3p/PI3K/AKT axis.Oct 03, 2021

Angiogenesis was induced via eNOS using thermal therapy in mice with hindlimb ischemia.Mar 31, 2006

Angiogenic function of astragaloside IV in rats with myocardial infarction occurs via the PKD1-HDAC5-VEGF pathway.Mar 31, 2019

Application of paeoniflorin represents a novel therapeutic approach for the treatment of cutaneous wounds.Jun 14, 2020

Astragaloside IV alleviated heart failure by promoting angiogenesis through JAK-STAT3 pathway.Nov 30, 2019

Astragaloside IV promotes angiogenesis by targeting SIRT7/VEGFA signaling pathway to improve brain injury after cerebral infarction.Oct 08, 2023

Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis.Feb 28, 2021

Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia.Dec 31, 2021

Baicalein has a protective effect of on muscle cells.Dec 31, 2015

Berberine can promote angiogenesis in the rat with cerebral ischemia-reperfusion injury.Sep 30, 2018

Berberine facilitates angiogenesis against ischemic stroke.Apr 23, 2019

Berberine via upregulation of miR-29b promotes ischemia-induced angiogenesis and improves heart functions.Jul 18, 2017

Both laser and LED light are capable of stimulating angiogenesis.Apr 30, 2013

Co-delivery of deferoxamine and hydroxysafflor yellow A to accelerate diabetic wound healing via enhanced angiogenesis.Oct 31, 2018

Cornin increases angiogenesis and improves functional recovery after strokeDec 31, 2015

Crocin and voluntary exercise promote heart angiogenesis through Akt and ERK1/2 signalling in type 2 diabetic rats.Dec 31, 2017

Curcumin pretreatment is a promising adjuvant strategy for stem cells transplantation in myocardial restoration. Dec 31, 2014

Curcumol promotes vascular endothelial growth factor-mediated diabetic wound healing.Jan 30, 2017

Diallyl trisulfide promotes placental angiogenesis by regulating lipid metabolism and alleviating inflammatory responses in obese pregnant mice.May 25, 2022

Dl-3-N-butylphthalide promotes angiogenesis in an optimized model of transient ischemic attack.Dec 31, 2020

Echinacoside promotes osteogenesis and angiogenesis and inhibits osteoclast formation.Mar 18, 2024

Effects of low-level laser therapy at wavelengths of 660 and 808 nm in experimental model of osteoarthritis.Dec 31, 2011

Effects of photobiomodulation therapy on functional recovery, angiogenesis and redox status in denervated muscle.Dec 31, 2020

Effects of quince gel and hesperidin mixture on experimental endometriosis.Aug 07, 2023

EGb761 reduces neuronal apoptosis and promotes angiogenesis in experimental intracerebral hemorrhage.Feb 08, 2017

Electroacupuncture attenuates ischemic injury after stroke and promotes angiogenesis.Dec 31, 2021

Electroacupuncture can up-regulate the expression of angiogenesis-related factors in middle cerebral artery occlusion.Oct 24, 2019

Electroacupuncture improves long-term survival of myocardial infarction mice.Mar 24, 2022

Electroacupuncture promotes angiogenesis by regulating miR-142-5p and activating ADAMTS1/PI3K/AKT pathway in ischemic stroke rats.Aug 24, 2024

Electroacupuncture promotes angiogenesis in mice with cerebral ischemia.May 31, 2024

Electroacupuncture promotes the survival of the grafted human MGE neural progenitors in rats with cerebral ischemia.Dec 31, 2020

Fermented black garlic could be used for reducing the risk of cardiovascular disease.Oct 06, 2019

Formononetin inhibits inflammation and promotes gastric mucosal angiogenesis in gastric ulcer.Oct 25, 2020

Fucoidan promotes angiogenesis and accelerates wound healing.May 17, 2023

Ginkgolide B targets and inhibits creatine kinase B to regulate the CCT/TRiC-SK1 axis and exerts pro-angiogenic activity in middle cerebral artery occlusion.May 31, 2022

Ginkgolide K promotes angiogenesis in a middle cerebral artery occlusion model.Aug 14, 2018

Ginsenoside Re is a novel angiogenic agent for tissue regeneration.Mar 31, 2005

Ginsenoside Rg1 exhibited protective effect against transverse aortic constriction-induced left ventricular hypertrophy and cardiac dysfunction.Jun 30, 2013

ginsenoside Rg1 promoted cerebral angiogenesis through increasing the expression of VEGF via PI3K/Akt/mTOR signaling pathway after ischemic stroke.May 23, 2019

Hesperidin could be used to enhance wound healing in chronic diabetic foot ulcers.Dec 31, 2017

Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.Jan 20, 2011

Icariin accelerates bone regeneration by inducing osteogenesis-angiogenesis coupling in rats with type 1 diabetes mellitus.Apr 14, 2024

Involvement of miR-126-3p via mTOR/HIF-1α signaling pathway in effect of electroacupuncture on angiogenesis in rats with cerebral ischemia.Sep 24, 2022

Korean red ginseng extract was found capable of inducing angiogenesis both in vivo and in vitro models.Sep 30, 2017

L-arginine ameliorates hypoxic pulmonary hypertension.Jun 01, 2009

LED treatment of ischemia challenged tissue improved early wound healing.Nov 30, 2014

LLLI may be an effective stem cell therapy for the treatment of hind-limb ischemia and peripheral vascular disease.Aug 31, 2017

Local administration of ginkgolide B using a hyaluronan-based hydrogel improves wound healing in diabetes.Dec 31, 2021

Long-term intermittent fasting improves neurological function by promoting angiogenesis after cerebral ischemia.Dec 31, 2022

Low molecular weight fucoidan alleviates cerebrovascular damage by promoting angiogenesis in type 2 diabetes mice.Jul 12, 2022

Magnesium and vitamin C supplementation attenuates steroid-associated osteonecrosis in a rat model.Jan 30, 2020

Mechanistic insights into tanshinone IIA in the amelioration of post-thyroidectomy hypoparathyroidism.Dec 31, 2023

Modulations of VEGF and iNOS in the rat heart by low level laser therapy are associated with cardioprotection and enhanced angiogenesis.Jul 31, 2006

Morroniside enhances angiogenesis and improves cardiac function following acute myocardial infarction.Apr 04, 2020

Naringin promotes fracture healing through stimulation of angiogenesis.Jan 04, 2017

Naringin-loaded Arabic gum/pectin hydrogel as a potential wound healing material.Sep 24, 2022

Notoginsenoside R1 activates the NAMPT-NAD +-SIRT1 cascade to promote postischemic angiogenesis.May 20, 2021

Angiogenesis Inducing Agents

View the Evidence:
127 Abstracts with Angiogenesis Inducing Agents Research