Anti-Apoptotic

Name	AC	CK
Ginsenosides	77	139
Curcumin	52	82
Tanshinone IIA	38	82
Astragaloside	35	70
Astaxanthin	42	64
Melatonin	36	61
Puerarin	36	60
Flavonoids	33	58
Vitamin C	24	54
Berberine	29	53
Resveratrol	33	53
Thymoquinone	28	49
Paeoniflorin	29	40
Quercetin	19	39
Apigenin	17	36
Citrus naringin	20	33
EGCG (Epigallocatechin gallate)	21	33
Grape Seed Extract	19	33
Gastrodin	17	31
Alpha-Lipoic Acid	14	27
Chrysin	16	27
Lycopene	16	26
Safflower	18	26
Selenium	13	26
Crocin	16	25
Ginkgo biloba	13	25
Kaempferol	11	24
Polyphenols	12	24
Ligustrazine	13	23
Hesperidin	11	22
Anthocyanins	14	21
Paeonol	13	21
Nobiletin	12	20
Asiatic Acid	12	19
Pomegranate	9	19
Genistein	10	18
Mangiferin	10	18
Royal Jelly	5	18
Catechin	7	17
Emodin	11	17
Fucoidan	12	17
Huperzine	10	17
Coenzyme Q10	10	16
Honokiol	10	16
Hydrogen Water	9	16
Moringa oleifera	9	16
Cannabidiol	10	15
NAC (N-acetyl-L-cysteine)	7	15
Myricetin	10	14
Nigella sativa (aka Black Seed)	8	14
Reishi Mushroom	8	14
Rutin	9	14
Sulforaphane	6	14
Vitamin E	8	14
Betulinic acid	7	13
Carnosic Acid	7	13
Chlorogenic Acid	8	13
Garlic	8	13
Pterostilbene	8	13
Punicalagin	6	13
Rose	9	13
Bergamot orange	2	12
Cordyceps sinensis	7	12
Ferulic acid	8	12
Fisetin	7	12
Ginger	6	12
Goji	9	12
Naringenin	8	12
Oleuropein	8	12
Probiotics	6	12
Sea buckthorn	2	12
Vitexins	9	12
Allicin	7	11
Baicalein	7	11
Ellagic Acid	7	11
Honeysuckle	8	11
Lotus	10	11
Persimmon	7	11
Turmeric	5	11
Vitamin D	5	11
Angelica	5	10
Blueberry	6	10
Caffeic acid phenethyl ester	6	10
Camel Milk	1	10
Eriodictyol	6	10
Fucoxanthin	5	10
Oleanolic acid	5	10
Saffron	6	10
Carvacrol	5	9
Dates	5	9
Dogwood	6	9
Gingerol	4	9
Hydroxytyrosol	5	9
Luteolin	7	9
Medicinal Mushrooms	5	9
Panax Notoginseng	6	9
Peony	7	9
Urolithin A	6	9
Bee Venom	5	8
Bilberry	5	8
Formononetin	5	8
Green Tea	5	8
P-Coumaric Acid	5	8
Piperine	5	8
Shikonin	4	8
Spirulina	4	8
Strawberry	4	8
Walnut	5	8
Apple	4	7
Astragalus	2	7
Beet	4	7
Biochanin A	4	7
Burdock	4	7
Carnosine	4	7
Curcuminoids	2	7
Delphinidin	3	7
Delta-tetrahydrocannabinol (THC)	3	7
Garlic: Aged	4	7
Geraniol	4	7
Gotu Kola	5	7
Isoliquiritigenin	5	7
Olive leaf extract	4	7
Rooibos	4	7
Rosemaric Acid	4	7
Ursolic Acid	4	7
Verbascoside	3	7
Water: Deep Sea	4	7
Ashwagandha	4	6
Celastrol	4	6
Chaga Mushroom (Inonotus obliquus)	3	6
Cordyceps Militaris	3	6
Cyanidin 3-glucoside	4	6
Diosgenin	3	6
Diosmin	3	6
Fermented Foods and Beverages	3	6
Licorice	4	6
Lion's Mane (Hericium Erinaceus)	5	6
Lychee	3	6
Magnolol	4	6
Neem	3	6
Nettle	3	6
Palmitoylethanolamide	3	6
Prickly Pear Cactus	3	6
Proanthocyanidins	4	6
Safranal	4	6
Sesamin	3	6
Sesamol	3	6
Zinc	4	6
Bee Propolis	3	5
Cocoa	3	5
Diosmetin	3	5
Eugenol	3	5
Fenugreek	3	5
Folic Acid	5	5
Ginseng (Korean)	4	5
Indole-3-Carbinol	4	5
Mangosteen	3	5
Okra	3	5
Onion	3	5
Theanine	3	5
Vanillin	3	5
Vitamin E: alpha tocopherol	4	5
White Mulberry	3	5
Agaricus Blazei	2	4
Aloe Vera	2	4
Apple Polyphenols	2	4
Arctigenin	2	4
Artesunate	2	4
Babchi	2	4
Bee Pollen	2	4
Bitter Melon	2	4
Black Pepper	2	4
Crocetin	2	4
Dandelion	3	4
Diallyl sulfide	2	4
Gynostemma	3	4
Lactobacillus paracasei	2	4
Olive	2	4
Oregano	2	4
Parthenolide	4	4
Phellinus Linteus	4	4
Piceatannol	4	4
Procyanidin B2	3	4
Propolis: Bee	2	4
Pycnogenol (Pine Bark)	2	4
Red Sage	2	4
Tannic Acid	2	4
Taurine	3	4
Tetrahydrocurcumin	3	4
Xanthohumol	2	4
Zerumbone	3	4
Amla Fruit	2	3
Bacopa	3	3
Bamboo	2	3
Barberry	2	3
Betaine	2	3
Bitter Orange	2	3
Butterbur	2	3
Capsaicin	2	3
Cardamonin	2	3
Chrysanthemum Indicum	2	3
Cryptoxanthin	2	3
Cyanidin	2	3
Frankincense	3	3
Ginseng	2	3
Guduchi	2	3
Hydrangea	2	3
Isoflavones	2	3
Kombucha Tea	2	3
Lactobacillus plantarum	2	3
Lactoferrin	3	3
Lemon Balm	2	3
Lentinan	2	3
Mugwort	2	3
Mulberry	2	3
Noni	2	3
Nordihydroguaiaretic acid (NDGA)	2	3
Oridonin	2	3
Poria cocos	2	3
Rosmarinic acid	2	3
Seaweed	2	3
Tangeretin	2	3
Theaflavins	2	3
Toona sinensis	2	3
Wogonin	2	3
acetyl-11-keto-beta-boswellic acid	2	3
6-Shogaol	2	2
Acacia catechu	1	2
Achiote	1	2
Agaricus brasiliensis	1	2
Antrodia camphorata	2	2
Apocynin	1	2
Apple Cider Vinegar	1	2
Apples	1	2
Apricot	1	2
Banaba	1	2
Banana	1	2
Barley	1	2
Basil	1	2
Berbamine	1	2
Bergamot	1	2
Beta Sitosterol	1	2
Beta-Caryophyllene	2	2
Bifidobacterium Longum	1	2
Black Currant	1	2
Black Raspberry	1	2
Bloodroot	1	2
Buckwheat	1	2
Carnosol	1	2
Carotenoids	2	2
Celery	1	2
Chamomile	1	2
Chlorella (Algae)	1	2
Chocolate	1	2
Cinnamon	1	2
Citrus Peel	1	2
Coconut Oil	1	2
Coriandrum sativum	1	2
Corn Silk	2	2
Coumestrol	1	2
Curry Tree	1	2
Cysteine (see N-Acetylcysteine)	1	2
DHA (Docosahexaenoic Acid)	1	2
Dong Quai	1	2
Eucalyptus	1	2
Evening Primrose Oil	1	2
False Black Pepper	1	2
Fig	1	2
Gardenia	1	2
Ginseng (American)	1	2
Glycyrrhiza uralensis	2	2
Graviola	1	2
Guava	1	2
Hibiscus sabdariffa	1	2
Honey	1	2
Hops	1	2
Hu Zhang (Polygonum cuspidatum)	1	2
Huaier (Trametes robiniophila murr)	1	2
Isoquercitrin	2	2
Japanese cypress	1	2
Kimchi	1	2
L-arginine	1	2
Lactobacillus helveticus	1	2
Lactobacillus reuteri	1	2
Lactobacillus rhamnosus GG	1	2
Lemon Verbena	1	2
Lingonberry	2	2
Long Pepper	1	2
Loquat	1	2
Milk Thistle	1	2
Nutmeg	1	2
Oligonol	1	2
Oligosaccharides	1	2
Omega-3 Fatty Acids	1	2
Orange	1	2
Panax Ginseng	1	2
Parsley	1	2
Perilla	1	2
Phloretin	2	2
Piperlongumine	1	2
Psychedelics:All	1	2
Psyllium	1	2
Raspberry ketone	1	2
Red Cabbage	1	2
Rhubarb	1	2
Rosemary	1	2
Salvia divinorum	1	2
Saw Palmetto	1	2
Shilajit	1	2
Silymarin	1	2
Spinach	1	2
St. Johns Wort	1	2
Star Fruit	1	2
Stilbenes	2	2
Sweet Potato	1	2
Sweet Potato: Purple	1	2
Syrian rue	1	2
Tauroursodeoxycholic acid	2	2
Terminalia	1	2
Thistle	2	2
Turkey Tail Mushroom	1	2
Ubiquinol	1	2
Vinegar	1	2
Vitamin B-3 (Niacin)	1	2
Water: Deuterium Depleted	1	2
Yellow Sweet Clover (Melilotus officinalis)	1	2
Yoghurt	1	2
neohesperidin	1	2
Adlay	1	1
Anandamide	1	1
Avenanthramides	1	1
Avocado	1	1
Ayurvedic formulation: Liv52	1	1
Bay Laurel	1	1
Beta-Elemene	1	1
Betanin	1	1
Betel	1	1
Bisdemethoxycurcumin	1	1
Black Tea Theaflavins	1	1
Caffeic Acid	1	1
Cannabinoids	1	1
Cannabis	1	1
Celery seed	1	1
Chokeberry	1	1
Cucurbitacin E	1	1
Daidzein	1	1
Dihydrocurcumin	1	1
Echinacea	1	1
Endocannabinoids	1	1
Galactooligosaccharides	1	1
Genipin	1	1
Glycyrrhizin	1	1
Grape	1	1
Grapefruit peel extract	1	1
Hawthorn	1	1
Hibiscus	1	1
Jujube	1	1
Kefir	1	1
Kiwifruit	1	1
Lignans	1	1
Lime	1	1
Liquiritigenin	1	1
Lupeol	1	1
Lutein	1	1
Magnolia	1	1
Maple	1	1
Oat Bran	1	1
Oats	1	1
Oleocanthal	1	1
Organosulfur Compounds	1	1
Orthosiphon	1	1
Patchouli	1	1
Phyllanthus emblica	1	1
Policosanol	1	1
Prunella vulgaris	1	1
Purslane	1	1
Raspberry	1	1
Red Clover	1	1
Salvia miltiorrhiza	1	1
Schisandra	1	1
Seaweed: Brown	1	1
Silibinin	1	1
Sweet Orange	1	1
Terminalia chebula	1	1
Tomatidine	1	1
Vitamin K2	1	1
Yerba Mate	1	1
Zataria multiflora	1	1
beta-Carotene	1	1

[+]

Cardioprotective effects and possible mechanisms of luteolin for myocardial ischemia-reperfusion injury.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Cardiovasc Med. 2022 ;9:685998. Epub 2022 Apr 25. PMID: 35548432

Article Published Date : Dec 31, 2021

Study Type : Meta Analysis, Review

Additional Links

Substances : Luteolin

Diseases : Myocardial Ischemia

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Malondialdehyde Down-regulation

[+]

Astragaloside IV exerts renal protective effects in animals with diabetes mellitus through multiple signalling pathways.Sep 14, 2020

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Pubmed Data : Pharmacol Res. 2020 Sep 15 ;160:105192. Epub 2020 Sep 15. PMID: 32942018

Article Published Date : Sep 14, 2020

Study Type : Meta Analysis, Review

Additional Links

Substances : Astragaloside

Diseases : Diabetic Nephropathy

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Renoprotective

[+]

Available findings demonstrated the preclinical evidence that Ginsenoside-Rb1 has a potential neuroprotective effects.Dec 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Med Phys. 2016 Jan-Mar;41(1):52-7. PMID: 27051171

Article Published Date : Dec 31, 2015

Study Type : Human Study

Additional Links

Substances : Royal Jelly

Diseases : Chemotherapy and Radiation Toxicity

Pharmacological Actions : Anti-Apoptotic, Radioprotective

[+]

Sea buckthorn leaf extracts protect neuronal PC-12 cells from oxidative stress.Jul 27, 2017

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Pubmed Data : Environ Toxicol. 2017 Feb ;32(2):630-644. Epub 2016 Mar 28. PMID: 28071871

Pubmed Data : Biol Trace Elem Res. 2014 Aug ;160(2):285-93. Epub 2014 Jun 27. PMID: 24965080

Article Published Date : Aug 01, 2014

Study Type : Human In Vitro

Additional Links

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Ellagic acid improves benign prostate hyperplasia.Jun 16, 2022

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Pubmed Data : Cell Death Dis. 2022 Jun 17 ;13(6):554. Epub 2022 Jun 17. PMID: 35715415

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Pubmed Data : Life Sci. 2020 Aug 15 ;255:117833. Epub 2020 May 22. PMID: 32450167

Article Published Date : Aug 14, 2020

Study Type : Animal Study

Additional Links

Substances : Oleuropein

Diseases : Inflammation, Ischemia, Kidney Damage, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors

[+]

Emodin promotes fibroblast apoptosis and prevents epidural fibrosis through PERK pathway in rats.Oct 09, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Neurol Res. 2020 Jul ;42(7):597-604. Epub 2020 Jun 4. PMID: 32497471

Article Published Date : Jun 30, 2020

Study Type : Animal Study

Additional Links

Substances : Pycnogenol (Pine Bark)

Diseases : Spinal Cord Injuries

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

Red ginseng oil promotes hair growth and protects skin against UVC radiation.Jun 30, 2021

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[+]

Administration of Nigella sativa can be used to prevent formaldehyde induced apoptosis and epithelial damage.Apr 30, 2017

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Pubmed Data : Niger J Clin Pract. 2017 May ;20(5):523-529. PMID: 28513508

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Pubmed Data : Biol Trace Elem Res. 2017 Nov ;180(1):153-163. Epub 2017 Mar 10. PMID: 28283953

Article Published Date : Oct 31, 2017

Study Type : Animal Study

Additional Links

Substances : Agaricus Blazei

Diseases : Cadmium Poisoning

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants

Problem Substances : Cadmium

[+]

AGE has an ameliorative effect against CP-induced oxidative stress and renal damage through its antioxidant, anti-inflammatory and antiapoptotic properties. Dec 31, 2013

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Pubmed Data : Cancer Cell Int. 2014 ;14(1):92. Epub 2014 Sep 28. PMID: 25298749

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Substances : Garlic: Aged

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Renoprotective

Additional Keywords : Plant Extracts

[+]

Click here to read the entire abstract

Pubmed Data : Andrologia. 2020 Jan 8:e13504. Epub 2020 Jan 8. PMID: 31912924

Article Published Date : Jan 07, 2020

Study Type : Animal Study

Additional Links

Substances : Curry Tree

Diseases : Bisphenol Toxicity, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Anti-Apoptotic, Antioxidants

Problem Substances : Bisphenol A

[+]

Alleviation of lead acetate-induced nephrotoxicity by Moringa oleifera extract.Jun 11, 2020

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Pubmed Data : Environ Sci Pollut Res Int. 2020 Jun 12. Epub 2020 Jun 12. PMID: 32529628

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Pubmed Data : Food Funct. 2021 Jan 21 ;12(2):696-705. Epub 2021 Jan 7. PMID: 33410857

Article Published Date : Jan 20, 2021

Study Type : Animal Study

Additional Links

Substances : Aloe Vera

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Alpha lipoic acid has a therapeutic role in ameliorating DOX-induced testicular damage.Mar 31, 2021

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Pubmed Data : Andrologia. 2021 Apr ;53(3):e13990. Epub 2021 Feb 2. PMID: 33529370

Article Published Date : Mar 31, 2021

Study Type : Animal Study

Additional Links

Substances : Alpha-Lipoic Acid

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Chemoprotective Agents

[+]

Alpha lipoic acid possess protective effects against chlorpyrifos induced liver injury.Feb 22, 2018

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Ameliorative potentials of the ethanolic extract from Lycium chinense leaf extract against diabetic cardiomyopathy.Sep 30, 2022

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Pubmed Data : Biomed Pharmacother. 2022 Oct ;154:113583. Epub 2022 Aug 19. PMID: 35994819

Article Published Date : Sep 30, 2022

Study Type : Animal Study

Additional Links

Substances : Goji

Diseases : Cardiomyopathy, Diabetic Complications

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

AMPK contributes to cardioprotective effects of pterostilbene against myocardial ischemia-reperfusion injury.Dec 31, 2017

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Pubmed Data : Toxicol Mech Methods. 2017 Jan 22:1-27. Epub 2017 Jan 22. PMID: 28110594

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Pubmed Data : Int J Mol Sci. 2019 Oct 11 ;20(20). Epub 2019 Oct 11. PMID: 31614480

Article Published Date : Oct 10, 2019

Study Type : Animal Study

Additional Links

Substances : Andrographis, Andrographolide

Diseases : Lipopolysaccharide-Induced Toxicity, Rheumatoid Arthritis

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents

[+]

Andrographolide contributes to spinal cord injury repair.Dec 31, 2021

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Pubmed Data : PLoS One. 2022 ;17(10):e0276984. Epub 2022 Oct 27. PMID: 36301972

Article Published Date : Dec 31, 2021

Study Type : Animal Study

Additional Links

Substances : Soursop

Diseases : Diabetic Complications

Pharmacological Actions : Alpha-glucosidase inhibitor , Anti-Apoptotic, Bcl-2 protein down-regulation, Hypoglycemic Agents

Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs

[+]

Antenatal pomegranate juice rescues hypoxia-induced fetal growth restriction in pregnant mice.May 31, 2018

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Pubmed Data : Placenta. 2018 Jun ;66:1-7. Epub 2018 Apr 16. PMID: 29884297

Article Published Date : May 31, 2018

Study Type : Animal Study

Additional Links

Substances : Pomegranate

Diseases : Hypoxia, Pregnancy Complications

Pharmacological Actions : Anti-Apoptotic, Antioxidants

[+]

Anthocyanin from purple sweet potato attenuates lead-induced reproductive toxicity mediated by JNK signaling pathway in male mice.Aug 23, 2021

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Pubmed Data : Ecotoxicol Environ Saf. 2021 Aug 24 ;224:112683. Epub 2021 Aug 24. PMID: 34438266

Article Published Date : Aug 23, 2021

Study Type : Animal Study

Additional Links

Substances : Anthocyanins, Sweet Potato: Purple

Diseases : Lead Poisoning, Male Reproductive Development Abnormalities

Pharmacological Actions : Anti-Apoptotic, Antioxidants

Problem Substances : Lead

[+]

Anthocyanin rich extract of red cabbage alleviates experimentally induced myocardial infarction.Dec 31, 2016

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Article Publish Status : This is a free article. Click here to read the complete article.

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Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:7973098. Epub 2019 Mar 20. PMID: 31015891

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Apigenin

Diseases : Myocardial Ischemia

Pharmacological Actions : Anti-Apoptotic, Cardioprotective

[+]

Apple extracts can extend cellular lifespan by lowering the level of intracellular ROS and by the activation of cellular signalling pathways.Apr 04, 2017

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Pubmed Data : Front Immunol. 2018 ;9:1881. Epub 2018 Aug 16. PMID: 30177931

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Arctigenin

Diseases : Hepatitis: Lectin-Induced (concanavalin)

Pharmacological Actions : Anti-Apoptotic, Autophagy Inhibitors, Hepatoprotective

Problem Substances : Concanavalin A

[+]

Arctium lappa could be considered a potentially valuable medicinal food for dry age-related macular degeneration.Apr 08, 2020

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Pubmed Data : PLoS One. 2016;11(6):e0157982. Epub 2016 Jun 23. PMID: 27336157

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Dry Eye Syndromes

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Natural Substance Synergy

[+]

Click here to read the entire abstract

Pubmed Data : Food Funct. 2016 Apr ;7(4):1999-2005. PMID: 26999333

Article Published Date : Mar 31, 2016

Study Type : Animal Study

Additional Links

Substances : Asiatic Acid

Diseases : Parkinson's Disease

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Asiatic acid may be a potential therapeutic agent for glaucoma.Dec 31, 2017

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Pubmed Data : Biomed Pharmacother. 2017 Sep 11 ;95:974-982. Epub 2017 Sep 11. PMID: 28915539

Article Published Date : Sep 10, 2017

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Lung Injury: Acute

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor

[+]

Astaxanthin ameliorates damage to the cerebral cortex, hippocampus and cerebellar cortex caused by methotrexate.Nov 30, 2021

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Pubmed Data : Biotech Histochem. 2021 Dec 1:1-12. Epub 2021 Dec 1. PMID: 34850645

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Pubmed Data : Mediators Inflamm. 2014 ;2014:954502. Epub 2014 Apr 17. PMID: 24860243

Article Published Date : Dec 31, 2013

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic

[+]

Astaxanthin improves cognitive deficits from oxidative stress in diabetes rats.Dec 31, 2014

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Pubmed Data : Drug Des Devel Ther. 2018 ;12:2785-2793. Epub 2018 Sep 6. PMID: 30233141

Article Published Date : Dec 31, 2017

Study Type : Animal Study

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Substances : Astragaloside

Diseases : Diabetic Nephropathy

Pharmacological Actions : Anti-Apoptotic

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Astragaloside IV attenuates cerebral ischemia‑reperfusion injury.Dec 31, 2020

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Pubmed Data : Int J Mol Med. 2020 Jul ;46(1):340-350. Epub 2020 Apr 23. PMID: 32626913

Article Published Date : Jun 30, 2020

Study Type : Animal Study

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Substances : Astragaloside

Diseases : Diabetic Retinopathy

Pharmacological Actions : Anti-Apoptotic, MicroRNA modulator

[+]

Astragaloside IV reduces cardiomyocyte apoptosis in a murine model of coxsackievirus B3-induced viral myocarditis.Jun 25, 2019

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Pubmed Data : Life Sci. 2016 Jan 15 ;145:213-23. Epub 2015 Dec 17. PMID: 26706290

Article Published Date : Jan 14, 2016

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Baicalein

Diseases : Heart Failure

Pharmacological Actions : Anti-Apoptotic, Cardioprotective, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Baicalein ameliorates myocardial ischemia through reduction of oxidative stress, inflammation and apoptosis.Dec 31, 2021

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Pubmed Data : BMC Complement Altern Med. 2016 ;16(1):120. Epub 2016 Apr 23. PMID: 27107819

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Pubmed Data : Food Funct. 2022 Aug 15 ;13(16):8436-8464. Epub 2022 Aug 15. PMID: 35861207

Article Published Date : Aug 14, 2022

Study Type : Animal Study

Additional Links

Substances : Procyanidin B2

Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Chemoprotective Agents, NF-kappaB Inhibitor, Renoprotective

[+]

Benzyl isothiocyanates modulate inflammation, oxidative stress, and apoptosis in indomethacin-induced gastric injury.Jul 06, 2021

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Pubmed Data : Food Funct. 2021 Jul 7 ;12(13):6001-6013. Epub 2021 May 26. PMID: 34037056

Article Published Date : Jul 06, 2021

Study Type : Animal Study

Additional Links

Substances : Benzyl isothiocyanate

Diseases : Drug-Induced Toxicity: Indomethacin, Gastric Ulcer, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Ulcer Agents, Heme oxygenase-1 up-regulation, NF-kappaB Inhibitor, Nrf2 activation

Problem Substances : Indomethacin

[+]

Berbamine ameliorates isoproterenol-induced myocardial infarction.Feb 28, 2019

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Pubmed Data : J Cell Biochem. 2019 Mar ;120(3):3101-3113. Epub 2018 Nov 28. PMID: 30485494

Article Published Date : Feb 28, 2019

Study Type : Animal Study

Additional Links

Substances : Berbamine

Diseases : Myocardial Infarction

Pharmacological Actions : Anti-Apoptotic, Cardioprotective

Problem Substances : Isoproterenol

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View the Evidence: 2375 Abstracts with Anti-Apoptotic Research

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Cardioprotective effects and possible mechanisms of luteolin for myocardial ischemia-reperfusion injury.Dec 31, 2021

Astragaloside IV exerts renal protective effects in animals with diabetes mellitus through multiple signalling pathways.Sep 14, 2020

Available findings demonstrated the preclinical evidence that Ginsenoside-Rb1 has a potential neuroprotective effects.Dec 31, 2019

Tanshinone IIA can effectively improve liver fibrosis and liver function.Dec 31, 2018

28‐days of polyphenol supplementation modulates the acute JNK, BAD, and Bcl‐2 response to heavy resistance exercise.Dec 31, 2017

7,8-dihydroxyflavone protects high glucose-damaged neuronal cells against oxidative stress.Dec 31, 2018

Berberine exhibits antioxidative effects and reduces apoptosis of the vaginal epithelium in bacterial vaginosis.Aug 31, 2019

Biological effects of rutin on skin aging.Jun 30, 2016

Camel milk had a regulatory effect on multiple parameters of inflammatory mediators, immunomodulators, antiapoptosis, and antioxidants.Oct 31, 2015

Cocoa procyanidins attenuate lipid peroxidation associated neuronal cell death in a manner relevant to Alzheimer's disease.May 15, 2009

Docosahexaenoic acid counteracts the hypoxic-induced inflammatory and metabolic alterations.Oct 31, 2022

Effect of vitamin C administration on neutrophil apoptosis in septic patients after abdominal surgery.May 14, 2009

Efficacy of tanshinone IIA and mesenchymal stem cell treatment of learning and memory impairment in a rat model of vascular dementia.Dec 31, 2020

Electroacupuncture can enhance oocyte maturation and fertilization rate, and reduce the granulosa-cell apoptosis index in an IVF program.Sep 30, 2019

Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults.Jan 21, 2020

Moderate-intensity exercise training ameliorates the diabetes-suppressed spermatogenesis and improves sperm parameters.Nov 30, 2019

Royal jelly consumption protects against radiation-induced apoptosis in human peripheral blood leukocytes.Dec 31, 2015

Sea buckthorn leaf extracts protect neuronal PC-12 cells from oxidative stress.Jul 27, 2017

Sudarshan Kriya practice may exert effects on immunity, aging, cell death, and stress regulation through transcriptional regulation.Jan 31, 2008

The in vivo transformation of bergamot juice phenolics in humans, may mitigate stearate-induced inflammation in myeloid angiogenic cells.Dec 05, 2017

Vitamin C inhibits endothelial cell apoptosis in congestive heart failure.Oct 29, 2001

6-Gingerol attenuates ischemia-reperfusion-induced cell apoptosis in human AC16 cardiomyocytes.Dec 31, 2018

Angelica and Astragalus could protect against oxidative stress-induced apoptosis in kidney epithelium.Feb 16, 2016

Apigenin could be a potent dietary anti-oxidant regimen against edifenphos-induced toxicity on human health.Apr 30, 2019

Apigenin reduces proteasome inhibition-induced neuronal apoptosis.Oct 31, 2016

Berberine alleviates myocardial ischemia-reperfusion injury.Nov 30, 2022

Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction. Jul 31, 2021

EGCG protected against the effects of Dihydrotestosterone (DHT) by altering the miRNA expression profile in human dermal papilla cells.May 31, 2016

Fisetin inhibits PM2.5-induced apoptosis by inhibiting the ER stress response and production of ROS.Sep 17, 2021

Fucoxanthin reduced the inflammation response and maintained the integrity of the blood-retinal barrier.Nov 24, 2020

Hesperidin shielded human keratinocytes from UVB radiation-induced damage and apoptosis.Jan 14, 2016

Mangiferin could ameliorate methylmercury mediated mitochondrial dysfunction in human hepatic cells in vitro.Jan 31, 2017

Maternal exposure to bisphenol A induces fetal growth restriction via upregulating the expression of estrogen receptors.Sep 13, 2021

NAC with its protective effects may be a potential compound for prevention of malathion-induced brain injury.Mar 31, 2019

Pomegranate juice attenuated the damaging effects of cigarette smoke on cultured human alveolar cells.Dec 31, 2015

Procyanidin B2 alleviates palmitic acid-Induced injury in HepG2 cells.Dec 31, 2020

Protective effects of acteoside against X‑ray‑induced damage in human skin fibroblasts.Jul 31, 2015

Protective effects of crocetin on arsenic trioxide-induced oxidative stress.Oct 31, 2021

Protective effects of delphinidin against H2O2-induced oxidative injuries in human retinal pigment epithelial cells.Aug 29, 2019

Punicalagin protects human retinal pigment epithelium cells from ultraviolet radiation-induced oxidative damage.Jun 01, 2020

Resveratrol protects against oxidized low‑density lipoprotein‑induced human umbilical vein endothelial cell apoptosis.Mar 08, 2017

Selenium prevents oxidative stress and apoptosis associated with mobile phone exposure.Aug 01, 2014

Self-assembled betulinic acid can be used to ameliorate the cytotoxic effects of Doxorubicin.Apr 30, 2015

Sulforaphane protects against ethanol-induced apoptosis in neural crest cells, a characteristic of Fetal Alcohol Syndrome, through restoration of Snail1 expression and epithelial-mesenchymal transition.Jul 08, 2019

THC exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.Sep 30, 2012

The present study suggests that Vitamin D3 is a potentially useful agent for limiting influenza A virus-induced cellular injury via its pro-autophagic action.Mar 27, 2020

This demonstrates the broad neuroprotective action of apigenin against AD pathogenesis in a human disease model.Dec 31, 2015

Turmeric extract and its curcuminoids provided significant protection against photooxidative damage and apoptosis retinal cells.Feb 28, 2017

Andrographolide alleviated blood-brain barrier disruption, neuronal apoptosis, and oxidative stress in subarachnoid hemorrhage.Mar 18, 2022

Anti-apoptotic and anti-inflammatory effects of an ethanolic extract of Lycium chinense root against particulate matter 10-induced cell death and inflammation.Sep 21, 2022

Ellagic acid improves benign prostate hyperplasia.Jun 16, 2022

Erinacine A prevents lipopolysaccharide-mediated glial cell activation to protect dopaminergic neurons against inflammatory factor-induced cell death.Jan 11, 2022

Ferulic acid ameliorates acetaminophen-induced acute liver injury.May 04, 2022

Ferulic acid attenuates high glucose-induced apoptosis in retinal pigment epithelium cells.Dec 31, 2021

Genistein attenuates memory impairment in Alzheimer's disease.Aug 02, 2022

Ginger efficiently reduced the lung damage and protected the lungs from severe damage due to hyperoxia and inflammation. Aug 15, 2018

Ginsenosides CK as a potential therapeutic approach for treating muscle-wasting conditions associated with obesity.Apr 30, 2022

Glabridin attenuates the retinal degeneration.Dec 31, 2019

In vitro and in vivo nephroprotective effects of Nelumbo nucifera seedpod extract against cisplatin-induced renal injury.Dec 01, 2022

Isorhamnetin alleviates lipopolysaccharide-induced acute lung injury.May 31, 2022

Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress.Jan 31, 2022

Multi-target effects of ß-caryophyllene and carnosic acid at the crossroads of mitochondrial dysfunction and neurodegeneration.Jun 17, 2022

Myricetin improves apoptosis after ischemic stroke via inhibiting MAPK-ERK pathway.Jan 07, 2023

Neuroprotective effects of a new triterpenoid from edible mushroom on oxidative stress and apoptosis.Nov 27, 2022

Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis‑fibroblast‑like synoviocytes.Dec 31, 2021

Procyanidin B2 ameliorates the progression of osteoarthritis.Oct 19, 2022

Protective effect of hydroxysafflor yellow A on cyclosporin A-induced renal oxidative stress.Dec 31, 2021

Protective mechanisms of 10-gingerol against myocardial ischemia.Jun 30, 2022

Sinensetin reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes.Dec 31, 2020

Taxifolin prevents diabetic cardiomyopathy in vivo and in vitro by inhibition of oxidative stress and cell apoptosis.Dec 31, 2013

Wogonin attenuates neutrophilic inflammation and airway smooth muscle proliferation.Nov 10, 2022

Effect of oleuropein on oxidative stress, inflammation and apoptosis induced by ischemia-reperfusion injury in rat kidney.Aug 14, 2020

Anti-Apoptotic

View the Evidence:
2375 Abstracts with Anti-Apoptotic Research