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Anti-Apoptotic
Views 2632
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389 Substances Researched for Anti-Apoptotic
Name
AC
CK
Focus
Ginsenosides
77
139
Curcumin
52
82
Tanshinone IIA
38
82
Astragaloside
35
70
Astaxanthin
42
64
Melatonin
36
61
Puerarin
36
60
Flavonoids
33
58
Vitamin C
24
54
Berberine
29
53
Resveratrol
33
53
Thymoquinone
28
49
Paeoniflorin
29
40
Quercetin
19
39
Apigenin
17
36
Citrus naringin
20
33
EGCG (Epigallocatechin gallate)
21
33
Grape Seed Extract
19
33
Gastrodin
17
31
Alpha-Lipoic Acid
14
27
Chrysin
16
27
Lycopene
16
26
Safflower
18
26
Selenium
13
26
Crocin
16
25
Ginkgo biloba
13
25
Kaempferol
11
24
Polyphenols
12
24
Ligustrazine
13
23
Hesperidin
11
22
Anthocyanins
14
21
Paeonol
13
21
Nobiletin
12
20
Asiatic Acid
12
19
Pomegranate
9
19
Genistein
10
18
Mangiferin
10
18
Royal Jelly
5
18
Catechin
7
17
Emodin
11
17
Fucoidan
12
17
Huperzine
10
17
Coenzyme Q10
10
16
Honokiol
10
16
Hydrogen Water
9
16
Moringa oleifera
9
16
Cannabidiol
10
15
NAC (N-acetyl-L-cysteine)
7
15
Myricetin
10
14
Nigella sativa (aka Black Seed)
8
14
Reishi Mushroom
8
14
Rutin
9
14
Sulforaphane
6
14
Vitamin E
8
14
Betulinic acid
7
13
Carnosic Acid
7
13
Chlorogenic Acid
8
13
Garlic
8
13
Pterostilbene
8
13
Punicalagin
6
13
Rose
9
13
Bergamot orange
2
12
Cordyceps sinensis
7
12
Ferulic acid
8
12
Fisetin
7
12
Ginger
6
12
Goji
9
12
Naringenin
8
12
Oleuropein
8
12
Probiotics
6
12
Sea buckthorn
2
12
Vitexins
9
12
Allicin
7
11
Baicalein
7
11
Ellagic Acid
7
11
Honeysuckle
8
11
Lotus
10
11
Persimmon
7
11
Turmeric
5
11
Vitamin D
5
11
Angelica
5
10
Blueberry
6
10
Caffeic acid phenethyl ester
6
10
Camel Milk
1
10
Eriodictyol
6
10
Fucoxanthin
5
10
Oleanolic acid
5
10
Saffron
6
10
Carvacrol
5
9
Dates
5
9
Dogwood
6
9
Gingerol
4
9
Hydroxytyrosol
5
9
Luteolin
7
9
Medicinal Mushrooms
5
9
Panax Notoginseng
6
9
Peony
7
9
Urolithin A
6
9
Bee Venom
5
8
Bilberry
5
8
Formononetin
5
8
Green Tea
5
8
P-Coumaric Acid
5
8
Piperine
5
8
Shikonin
4
8
Spirulina
4
8
Strawberry
4
8
Walnut
5
8
Apple
4
7
Astragalus
2
7
Beet
4
7
Biochanin A
4
7
Burdock
4
7
Carnosine
4
7
Curcuminoids
2
7
Delphinidin
3
7
Delta-tetrahydrocannabinol (THC)
3
7
Garlic: Aged
4
7
Geraniol
4
7
Gotu Kola
5
7
Isoliquiritigenin
5
7
Olive leaf extract
4
7
Rooibos
4
7
Rosemaric Acid
4
7
Ursolic Acid
4
7
Verbascoside
3
7
Water: Deep Sea
4
7
Ashwagandha
4
6
Celastrol
4
6
Chaga Mushroom (Inonotus obliquus)
3
6
Cordyceps Militaris
3
6
Cyanidin 3-glucoside
4
6
Diosgenin
3
6
Diosmin
3
6
Fermented Foods and Beverages
3
6
Licorice
4
6
Lion's Mane (Hericium Erinaceus)
5
6
Lychee
3
6
Magnolol
4
6
Neem
3
6
Nettle
3
6
Palmitoylethanolamide
3
6
Prickly Pear Cactus
3
6
Proanthocyanidins
4
6
Safranal
4
6
Sesamin
3
6
Sesamol
3
6
Zinc
4
6
Bee Propolis
3
5
Cocoa
3
5
Diosmetin
3
5
Eugenol
3
5
Fenugreek
3
5
Folic Acid
5
5
Ginseng (Korean)
4
5
Indole-3-Carbinol
4
5
Mangosteen
3
5
Okra
3
5
Onion
3
5
Theanine
3
5
Vanillin
3
5
Vitamin E: alpha tocopherol
4
5
White Mulberry
3
5
Agaricus Blazei
2
4
Aloe Vera
2
4
Apple Polyphenols
2
4
Arctigenin
2
4
Artesunate
2
4
Babchi
2
4
Bee Pollen
2
4
Bitter Melon
2
4
Black Pepper
2
4
Crocetin
2
4
Dandelion
3
4
Diallyl sulfide
2
4
Gynostemma
3
4
Lactobacillus paracasei
2
4
Olive
2
4
Oregano
2
4
Parthenolide
4
4
Phellinus Linteus
4
4
Piceatannol
4
4
Procyanidin B2
3
4
Propolis: Bee
2
4
Pycnogenol (Pine Bark)
2
4
Red Sage
2
4
Tannic Acid
2
4
Taurine
3
4
Tetrahydrocurcumin
3
4
Xanthohumol
2
4
Zerumbone
3
4
Amla Fruit
2
3
Bacopa
3
3
Bamboo
2
3
Barberry
2
3
Betaine
2
3
Bitter Orange
2
3
Butterbur
2
3
Capsaicin
2
3
Cardamonin
2
3
Chrysanthemum Indicum
2
3
Cryptoxanthin
2
3
Cyanidin
2
3
Frankincense
3
3
Ginseng
2
3
Guduchi
2
3
Hydrangea
2
3
Isoflavones
2
3
Kombucha Tea
2
3
Lactobacillus plantarum
2
3
Lactoferrin
3
3
Lemon Balm
2
3
Lentinan
2
3
Mugwort
2
3
Mulberry
2
3
Noni
2
3
Nordihydroguaiaretic acid (NDGA)
2
3
Oridonin
2
3
Poria cocos
2
3
Rosmarinic acid
2
3
Seaweed
2
3
Tangeretin
2
3
Theaflavins
2
3
Toona sinensis
2
3
Wogonin
2
3
acetyl-11-keto-beta-boswellic acid
2
3
6-Shogaol
2
2
Acacia catechu
1
2
Achiote
1
2
Agaricus brasiliensis
1
2
Antrodia camphorata
2
2
Apocynin
1
2
Apple Cider Vinegar
1
2
Apples
1
2
Apricot
1
2
Banaba
1
2
Banana
1
2
Barley
1
2
Basil
1
2
Berbamine
1
2
Bergamot
1
2
Beta Sitosterol
1
2
Beta-Caryophyllene
2
2
Bifidobacterium Longum
1
2
Black Currant
1
2
Black Raspberry
1
2
Bloodroot
1
2
Buckwheat
1
2
Carnosol
1
2
Carotenoids
2
2
Celery
1
2
Chamomile
1
2
Chlorella (Algae)
1
2
Chocolate
1
2
Cinnamon
1
2
Citrus Peel
1
2
Coconut Oil
1
2
Coriandrum sativum
1
2
Corn Silk
2
2
Coumestrol
1
2
Curry Tree
1
2
Cysteine (see N-Acetylcysteine)
1
2
DHA (Docosahexaenoic Acid)
1
2
Dong Quai
1
2
Eucalyptus
1
2
Evening Primrose Oil
1
2
False Black Pepper
1
2
Fig
1
2
Gardenia
1
2
Ginseng (American)
1
2
Glycyrrhiza uralensis
2
2
Graviola
1
2
Guava
1
2
Hibiscus sabdariffa
1
2
Honey
1
2
Hops
1
2
Hu Zhang (Polygonum cuspidatum)
1
2
Huaier (Trametes robiniophila murr)
1
2
Isoquercitrin
2
2
Japanese cypress
1
2
Kimchi
1
2
L-arginine
1
2
Lactobacillus helveticus
1
2
Lactobacillus reuteri
1
2
Lactobacillus rhamnosus GG
1
2
Lemon Verbena
1
2
Lingonberry
2
2
Long Pepper
1
2
Loquat
1
2
Milk Thistle
1
2
Nutmeg
1
2
Oligonol
1
2
Oligosaccharides
1
2
Omega-3 Fatty Acids
1
2
Orange
1
2
Panax Ginseng
1
2
Parsley
1
2
Perilla
1
2
Phloretin
2
2
Piperlongumine
1
2
Psychedelics:All
1
2
Psyllium
1
2
Raspberry ketone
1
2
Red Cabbage
1
2
Rhubarb
1
2
Rosemary
1
2
Salvia divinorum
1
2
Saw Palmetto
1
2
Shilajit
1
2
Silymarin
1
2
Spinach
1
2
St. Johns Wort
1
2
Star Fruit
1
2
Stilbenes
2
2
Sweet Potato
1
2
Sweet Potato: Purple
1
2
Syrian rue
1
2
Tauroursodeoxycholic acid
2
2
Terminalia
1
2
Thistle
2
2
Turkey Tail Mushroom
1
2
Ubiquinol
1
2
Vinegar
1
2
Vitamin B-3 (Niacin)
1
2
Water: Deuterium Depleted
1
2
Yellow Sweet Clover (Melilotus officinalis)
1
2
Yoghurt
1
2
neohesperidin
1
2
Adlay
1
1
Anandamide
1
1
Avenanthramides
1
1
Avocado
1
1
Ayurvedic formulation: Liv52
1
1
Bay Laurel
1
1
Beta-Elemene
1
1
Betanin
1
1
Betel
1
1
Bisdemethoxycurcumin
1
1
Black Tea Theaflavins
1
1
Caffeic Acid
1
1
Cannabinoids
1
1
Cannabis
1
1
Celery seed
1
1
Chokeberry
1
1
Cucurbitacin E
1
1
Daidzein
1
1
Dihydrocurcumin
1
1
Echinacea
1
1
Endocannabinoids
1
1
Galactooligosaccharides
1
1
Genipin
1
1
Glycyrrhizin
1
1
Grape
1
1
Grapefruit peel extract
1
1
Hawthorn
1
1
Hibiscus
1
1
Jujube
1
1
Kefir
1
1
Kiwifruit
1
1
Lignans
1
1
Lime
1
1
Liquiritigenin
1
1
Lupeol
1
1
Lutein
1
1
Magnolia
1
1
Maple
1
1
Oat Bran
1
1
Oats
1
1
Oleocanthal
1
1
Organosulfur Compounds
1
1
Orthosiphon
1
1
Patchouli
1
1
Phyllanthus emblica
1
1
Policosanol
1
1
Prunella vulgaris
1
1
Purslane
1
1
Raspberry
1
1
Red Clover
1
1
Salvia miltiorrhiza
1
1
Schisandra
1
1
Seaweed: Brown
1
1
Silibinin
1
1
Sweet Orange
1
1
Terminalia chebula
1
1
Tomatidine
1
1
Vitamin K2
1
1
Yerba Mate
1
1
Zataria multiflora
1
1
beta-Carotene
1
1
Research Articles
1672
Cumulative Knowledge Score
2705
Overall Research Rating
EXCELLENT
View the Evidence:
2696 Abstracts with Anti-Apoptotic Research
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[+]
Cardioprotective effects and possible mechanisms of luteolin for myocardial ischemia-reperfusion injury.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Cardiovasc Med. 2022 ;9:685998. Epub 2022 Apr 25. PMID:
35548432
Article Published Date
: Dec 31, 2021
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Luteolin
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Malondialdehyde Down-regulation
[+]
Ginkgolide B for myocardial ischemia/Reperfusion injury.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Physiol. 2019 ;10:1292. Epub 2019 Oct 16. PMID:
31681006
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Ischemia: Myocardial
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
[+]
The effect of ginsenosides on liver injury.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2023 ;14:1184774. Epub 2023 May 11. PMID:
37251340
Article Published Date
: Dec 31, 2022
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Astragaloside IV exerts renal protective effects in animals with diabetes mellitus through multiple signalling pathways.
Sep 14, 2020
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2020 Sep 15 ;160:105192. Epub 2020 Sep 15. PMID:
32942018
Article Published Date
: Sep 14, 2020
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Astragaloside
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Renoprotective
[+]
Available findings demonstrated the preclinical evidence that Ginsenoside-Rb1 has a potential neuroprotective effects.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2020 ;11:285. Epub 2020 Mar 31. PMID:
32296332
Article Published Date
: Dec 31, 2019
Study Type
: Meta Analysis, Review
Additional Links
Substances
:
Ginsenosides
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Neurogenesis
,
Neuroprotective Agents
[+]
Tanshinone IIA can effectively improve liver fibrosis and liver function.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:7514046. Epub 2019 Dec 13. PMID:
31915451
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Liver Fibrosis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
28‐days of polyphenol supplementation modulates the acute JNK, BAD, and Bcl‐2 response to heavy resistance exercise.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Physiol Rep. 2018 Jan ;6(2). PMID:
29380956
Article Published Date
: Dec 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Polyphenols
Diseases
:
Muscle Damage: Exercise-Induced
Therapeutic Actions
:
Exercise: Resistance Training
Pharmacological Actions
:
Anti-Apoptotic
[+]
7,8-dihydroxyflavone protects high glucose-damaged neuronal cells against oxidative stress.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomol Ther (Seoul). 2019 01 1 ;27(1):85-91. PMID:
30481956
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Diabetic Neuropathy
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
[+]
Berberine exhibits antioxidative effects and reduces apoptosis of the vaginal epithelium in bacterial vaginosis.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2019 Sep ;18(3):2122-2130. Epub 2019 Jul 12. PMID:
31410167
Article Published Date
: Aug 31, 2019
Study Type
: Human Study
Additional Links
Substances
:
Berberine
Diseases
:
Bacterial Vaginosis
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Biological effects of rutin on skin aging.
Jun 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2016 Jul ;38(1):357-63. Epub 2016 May 24. PMID:
27220601
Article Published Date
: Jun 30, 2016
Study Type
: Human Study
Additional Links
Substances
:
Rutin
Diseases
:
Aging Skin
,
Wrinkles
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
MicroRNA modulator
[+]
Camel milk had a regulatory effect on multiple parameters of inflammatory mediators, immunomodulators, antiapoptosis, and antioxidants.
Oct 31, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 Nov-Dec;67(8):1305-13. Epub 2015 Oct 22. PMID:
26492130
Article Published Date
: Oct 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Camel Milk
Diseases
:
Hepatitis C
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Immunomodulatory
,
Interleukin-10 upregulation
Additional Keywords
:
Vitamin D3
[+]
Cocoa procyanidins attenuate lipid peroxidation associated neuronal cell death in a manner relevant to Alzheimer's disease.
May 15, 2009
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2009 May 15;46(10):1319-27. Epub 2009 Feb 25. PMID:
19248828
Article Published Date
: May 15, 2009
Study Type
: Human Study
Additional Links
Substances
:
Catechin
Diseases
:
Alzheimer's Disease
,
Neurodegenerative Diseases
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
Additional Keywords
:
Proanthocyanidins
[+]
Docosahexaenoic acid counteracts the hypoxic-induced inflammatory and metabolic alterations.
Oct 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2022 Nov 1 ;14(21). Epub 2022 Nov 1. PMID:
36364860
Article Published Date
: Oct 31, 2022
Study Type
: Human Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
Diseases
:
Hypoxia
,
Inflammation
,
Obesity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hypoxia-inducible factor-1 (HIF-1) inhibitor
,
Interleukin-6 Downregulation
Additional Keywords
:
Anti-Obesity Agents
[+]
Effect of vitamin C administration on neutrophil apoptosis in septic patients after abdominal surgery.
May 14, 2009
Click here to read the entire abstract
Pubmed Data
: J Surg Res. 2009 May 15 ;153(2):224-30. Epub 2008 May 21. PMID:
18952228
Article Published Date
: May 14, 2009
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Sepsis
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Efficacy of tanshinone IIA and mesenchymal stem cell treatment of learning and memory impairment in a rat model of vascular dementia.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: J Tradit Chin Med. 2021 02 ;41(1):133-139. PMID:
33522206
Article Published Date
: Dec 31, 2020
Study Type
: Human Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Dementia
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
Additional Keywords
:
Mesenchymal Stem Cells
[+]
Electroacupuncture can enhance oocyte maturation and fertilization rate, and reduce the granulosa-cell apoptosis index in an IVF program.
Sep 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Med Acupunct. 2019 Oct 1 ;31(5):289-297. Epub 2019 Oct 17. PMID:
31624528
Article Published Date
: Sep 30, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Infertility: Female
Therapeutic Actions
:
Electroacupuncture
Pharmacological Actions
:
Anti-Apoptotic
,
Fertility Agents: Female
[+]
Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults.
Jan 21, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2020 07 22 ;10(1):12130. Epub 2020 Jul 22. PMID:
32699287
Article Published Date
: Jan 21, 2020
Study Type
: Human Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Inflammation
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
[+]
Moderate-intensity exercise training ameliorates the diabetes-suppressed spermatogenesis and improves sperm parameters.
Nov 30, 2019
Click here to read the entire abstract
Pubmed Data
: Andrologia. 2019 Dec ;51(11):e13457. Epub 2019 Oct 23. PMID:
31642094
Article Published Date
: Nov 30, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Diabetic Complications
,
Infertility: Male
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Fertility Agents: Male
[+]
Royal jelly consumption protects against radiation-induced apoptosis in human peripheral blood leukocytes.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Med Phys. 2016 Jan-Mar;41(1):52-7. PMID:
27051171
Article Published Date
: Dec 31, 2015
Study Type
: Human Study
Additional Links
Substances
:
Royal Jelly
Diseases
:
Chemotherapy and Radiation Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Radioprotective
[+]
Sea buckthorn leaf extracts protect neuronal PC-12 cells from oxidative stress.
Jul 27, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Microbiol Biotechnol. 2017 Jul 28 ;27(7):1257-1265. PMID:
28535611
Article Published Date
: Jul 27, 2017
Study Type
: Human Study
Additional Links
Substances
:
Flavonoids
,
Kaempferol
,
Quercetin
,
Sea buckthorn
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
Sudarshan Kriya practice may exert effects on immunity, aging, cell death, and stress regulation through transcriptional regulation.
Jan 31, 2008
Click here to read the entire abstract
Pubmed Data
: J Psychosom Res. 2008 Feb ;64(2):213-8. PMID:
18222135
Article Published Date
: Jan 31, 2008
Study Type
: Human Study
Additional Links
Diseases
:
Aging
,
DNA damage
,
Oxidative Stress
Therapeutic Actions
:
Yogic Technique: Sudarshan kriya
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
Additional Keywords
:
Gene Expression Regulation
[+]
The in vivo transformation of bergamot juice phenolics in humans, may mitigate stearate-induced inflammation in myeloid angiogenic cells.
Dec 05, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Dec 6 ;9(12). Epub 2017 Dec 6. PMID:
29211032
Article Published Date
: Dec 05, 2017
Study Type
: Human Study
Additional Links
Substances
:
Bergamot orange
Diseases
:
Endothelial Damage
,
Inflammation
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Vitamin C inhibits endothelial cell apoptosis in congestive heart failure.
Oct 29, 2001
Click here to read the entire abstract
Pubmed Data
: Circulation. 2001 Oct 30 ;104(18):2182-7. PMID:
11684628
Article Published Date
: Oct 29, 2001
Study Type
: Human Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Endothelial Dysfunction
,
Heart Failure
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Enzyme Inhibitors
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Panax ginseng alleviates benign prostatic hyperplasia while preventing finasteride-induced side effects.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2023 ;14:1039622. Epub 2023 Jan 12. PMID:
36713838
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Prostatic Hyperplasia: Benign
Pharmacological Actions
:
Anti-Apoptotic
[+]
6-Gingerol attenuates ischemia-reperfusion-induced cell apoptosis in human AC16 cardiomyocytes.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2019 ;2019:8798653. Epub 2019 Feb 11. PMID:
30886640
Article Published Date
: Dec 31, 2018
Study Type
: Human In Vitro
Additional Links
Substances
:
Gingerol
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Angelica and Astragalus could protect against oxidative stress-induced apoptosis in kidney epithelium.
Feb 16, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Feb 17 ;179:412-9. Epub 2015 Dec 21. PMID:
26719285
Article Published Date
: Feb 16, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Angelica
,
Astragalus
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
,
Renoprotective
[+]
Apigenin could be a potent dietary anti-oxidant regimen against edifenphos-induced toxicity on human health.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2019 May ;127:218-227. Epub 2019 Mar 22. PMID:
30910686
Article Published Date
: Apr 30, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
DNA damage
,
Lipid Peroxidation
,
Oxidative Stress
,
Pesticide-Induced Toxicity: Organophosphates
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
Problem Substances
:
Organophosphate Pesticides
[+]
Apigenin reduces proteasome inhibition-induced neuronal apoptosis.
Oct 31, 2016
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2016 Nov ;41(11):2969-2980. Epub 2016 Aug 29. PMID:
27473386
Article Published Date
: Oct 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
[+]
Berberine alleviates myocardial ischemia-reperfusion injury.
Nov 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2022 Dec ;60(1):652-663. PMID:
35311466
Article Published Date
: Nov 30, 2022
Study Type
: Human In Vitro
Additional Links
Substances
:
Berberine
Diseases
:
Inflammation
,
Myocardial Ischemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Cyclooxygenase 2 Inhibitors
[+]
Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction.
Jul 31, 2021
Click here to read the entire abstract
Pubmed Data
: J Recept Signal Transduct Res. 2021 Aug ;41(4):378-392. Epub 2020 Sep 9. PMID:
32900249
Article Published Date
: Jul 31, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Chicoric Acid
Diseases
:
Endothelial Dysfunction
,
Hyperglycemia
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
[+]
EGCG protected against the effects of Dihydrotestosterone (DHT) by altering the miRNA expression profile in human dermal papilla cells.
May 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ann Dermatol. 2016 Jun ;28(3):327-34. Epub 2016 May 25. PMID:
27274631
Article Published Date
: May 31, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Alopecia
,
Hair Loss
Pharmacological Actions
:
Anti-Apoptotic
,
MicroRNA modulator
[+]
Fisetin inhibits PM2.5-induced apoptosis by inhibiting the ER stress response and production of ROS.
Sep 17, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2021 Sep 18 ;10(9). Epub 2021 Sep 18. PMID:
34573124
Article Published Date
: Sep 17, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Fisetin
Diseases
:
Air Pollution Linked Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Fucoxanthin reduced the inflammation response and maintained the integrity of the blood-retinal barrier.
Nov 24, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2020 Nov 25 ;9(12). Epub 2020 Nov 25. PMID:
33255669
Article Published Date
: Nov 24, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Fucoxanthin
Diseases
:
Diabetic Retinopathy
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
[+]
Hesperidin shielded human keratinocytes from UVB radiation-induced damage and apoptosis.
Jan 14, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomol Ther (Seoul). 2016 Jan 15. Epub 2016 Jan 15. PMID:
26797112
Article Published Date
: Jan 14, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Hesperidin
Diseases
:
Oxidative Stress
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Photoprotective
[+]
Mangiferin could ameliorate methylmercury mediated mitochondrial dysfunction in human hepatic cells in vitro.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2017 Feb ;32(2):630-644. Epub 2016 Mar 28. PMID:
28071871
Article Published Date
: Jan 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Mangiferin
Diseases
:
Chemically-Induced Liver Damage
,
Mercury Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Methylmercury
Problem Substances
:
Mercury
[+]
Maternal exposure to bisphenol A induces fetal growth restriction via upregulating the expression of estrogen receptors.
Sep 13, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Chemosphere. 2021 Sep 14 ;287(Pt 3):132244. Epub 2021 Sep 14. PMID:
34537452
Article Published Date
: Sep 13, 2021
Study Type
: Human In Vitro
Additional Links
Diseases
:
Bisphenol Toxicity
,
Prenatal Chemical Exposures
Pharmacological Actions
:
Anti-Apoptotic
Problem Substances
:
Bisphenol A
[+]
NAC with its protective effects may be a potential compound for prevention of malathion-induced brain injury.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2019 Apr 1 ;417:1-14. Epub 2019 Feb 12. PMID:
30769050
Article Published Date
: Mar 31, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Pesticide-Induced Toxicity: Organophosphates
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
Problem Substances
:
Organophosphate Pesticides
[+]
Pomegranate juice attenuated the damaging effects of cigarette smoke on cultured human alveolar cells.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Chron Obstruct Pulmon Dis. 2016 ;11:227-37. Epub 2016 Feb 3. PMID:
26893554
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, Human In Vitro
Additional Links
Substances
:
Pomegranate
Diseases
:
Inflammation
,
Lung Injury: Smoke-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Procyanidin B2 alleviates palmitic acid-Induced injury in HepG2 cells.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2021 ;2021:8920757. Epub 2021 Dec 16. PMID:
34956386
Article Published Date
: Dec 31, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Procyanidin B2
Diseases
:
Chemically-Induced Liver Damage
,
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Protective effects of acteoside against X‑ray‑induced damage in human skin fibroblasts.
Jul 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2015 Aug ;12(2):2301-6. Epub 2015 Apr 16. PMID:
25892089
Article Published Date
: Jul 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Verbascoside
Diseases
:
Chemotherapy and Radiation Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Bcl-2 protein down-regulation
,
Radioprotective
[+]
Protective effects of crocetin on arsenic trioxide-induced oxidative stress.
Oct 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: In Vivo. 2021 Nov-Dec;35(6):3157-3163. PMID:
34697146
Article Published Date
: Oct 31, 2021
Study Type
: Human In Vitro
Additional Links
Substances
:
Crocetin
Diseases
:
Chemotherapy-Induced Toxicity: Arsenic Trioxide
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Chemoprotective Agents
Problem Substances
:
Arsenic Trioxide
[+]
Protective effects of delphinidin against H2O2-induced oxidative injuries in human retinal pigment epithelial cells.
Aug 29, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biosci Rep. 2019 Aug 30 ;39(8). Epub 2019 Aug 15. PMID:
31345961
Article Published Date
: Aug 29, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Delphinidin
Diseases
:
Hydrogen Peroxide Induced Toxicity
,
Macular Degeneration
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Nrf2 activation
[+]
Punicalagin protects human retinal pigment epithelium cells from ultraviolet radiation-induced oxidative damage.
Jun 01, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Antioxidants (Basel). 2020 Jun 2 ;9(6). Epub 2020 Jun 2. PMID:
32498245
Article Published Date
: Jun 01, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Punicalagin
Diseases
:
Eye Damage
,
Photooxidative Stress
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Resveratrol protects against oxidized low‑density lipoprotein‑induced human umbilical vein endothelial cell apoptosis.
Mar 08, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2017 Mar 9. Epub 2017 Mar 9. PMID:
28447714
Article Published Date
: Mar 08, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Endothelial Damage
,
Lipid Peroxidation
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Resveratrol's neural protective effects for the injured embryoid body and cerebral organoid.
Jul 11, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Pharmacol Toxicol. 2022 Jul 12 ;23(1):47. Epub 2022 Jul 12. PMID:
35820950
Article Published Date
: Jul 11, 2022
Study Type
: Human In Vitro
Additional Links
Substances
:
Resveratrol
Diseases
:
Alzheimer's Disease
,
Amyotrophic Lateral Sclerosis
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Selenium prevents oxidative stress and apoptosis associated with mobile phone exposure.
Aug 01, 2014
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2014 Aug ;160(2):285-93. Epub 2014 Jun 27. PMID:
24965080
Article Published Date
: Aug 01, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Selenium
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidant
,
Cytoprotective
Additional Keywords
:
electromagnetic fields
,
electromagnetic frequencies
,
electromagnetic radiation
,
EMF
Anti Therapeutic Actions
:
Electromagnetic Field Harms
,
Electromagnetic Radiation
,
Microwave Radiation
,
Mobile Phone Radiation
Problem Substances
:
Cell Phone Exposure
Adverse Pharmacological Actions
:
Apoptotic
,
Cytotoxic
,
Oxidant
[+]
Self-assembled betulinic acid can be used to ameliorate the cytotoxic effects of Doxorubicin.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2015 May ;72:144-57. Epub 2015 Apr 24. PMID:
26054689
Article Published Date
: Apr 30, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Betulinic acid
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Chemoprotective Agents
[+]
Sulforaphane protects against ethanol-induced apoptosis in neural crest cells, a characteristic of Fetal Alcohol Syndrome, through restoration of Snail1 expression and epithelial-mesenchymal transition.
Jul 08, 2019
Click here to read the entire abstract
Pubmed Data
: Biochim Biophys Acta Mol Basis Dis. 2019 Jul 8 ;1865(10):2586-2594. Epub 2019 Jul 8. PMID:
31295528
Article Published Date
: Jul 08, 2019
Study Type
: Human In Vitro
Additional Links
Substances
:
Sulforaphane
Diseases
:
Fetal Alcoholism
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
Additional Keywords
:
Alcohol
,
Broccoli
,
Broccoli Sprouts
,
Cruciferous Vegetables
,
Mesenchymal Stem Cells
,
Pregnancy And Fetal Growth
[+]
THC exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.
Sep 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Neuropathol Appl Neurobiol. 2012 Oct ;38(6):535-47. PMID:
22236282
Article Published Date
: Sep 30, 2012
Study Type
: Human In Vitro
Additional Links
Substances
:
Delta-tetrahydrocannabinol (THC)
Diseases
:
Oxidative Stress
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
The present study suggests that Vitamin D3 is a potentially useful agent for limiting influenza A virus-induced cellular injury via its pro-autophagic action.
Mar 27, 2020
Click here to read the entire abstract
Pubmed Data
: Virus Res. 2020 Mar 28 ;282:197936. Epub 2020 Mar 28. PMID:
32234325
Article Published Date
: Mar 27, 2020
Study Type
: Human In Vitro
Additional Links
Substances
:
Vitamin D
Diseases
:
Influenza A
Pharmacological Actions
:
Anti-Apoptotic
[+]
This demonstrates the broad neuroprotective action of apigenin against AD pathogenesis in a human disease model.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 ;6:31450. Epub 2016 Aug 12. PMID:
27514990
Article Published Date
: Dec 31, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Apigenin
Diseases
:
Alzheimer's Disease
,
Brain Inflammation
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Turmeric extract and its curcuminoids provided significant protection against photooxidative damage and apoptosis retinal cells.
Feb 28, 2017
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2017 Mar ;69(3):334-340. Epub 2017 Feb 3. PMID:
28155996
Article Published Date
: Feb 28, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcuminoids
,
Turmeric
Diseases
:
Macular Degeneration
,
Photooxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Photoprotective
[+]
The protective role of sulforaphane and Homer1a in retinal ischemia-reperfusion injury.
Sep 14, 2023
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2023 Sep 15 ;329:121968. Epub 2023 Jul 22. PMID:
37487941
Article Published Date
: Sep 14, 2023
Study Type
: Animal Study, Transgenic Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Eye Damage
,
Optic Nerve Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Acacetin attenuates diabetes-induced cardiomyopathy.
May 04, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Eur J Pharmacol. 2022 May 5 ;922:174916. Epub 2022 Mar 24. PMID:
35341782
Article Published Date
: May 04, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Diabetes: Cardiovascular Illness
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Interleukin-6 Downregulation
[+]
Andrographolide alleviated blood-brain barrier disruption, neuronal apoptosis, and oxidative stress in subarachnoid hemorrhage.
Mar 18, 2022
Click here to read the entire abstract
Pubmed Data
: Neurotox Res. 2022 Mar 19. Epub 2022 Mar 19. PMID:
35305248
Article Published Date
: Mar 18, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Andrographolide
Diseases
:
Subarachnoid hemorrhage
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Andrographolide inhibits static mechanical pressure-induced intervertebral disc degeneration.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2023 ;17:535-550. Epub 2023 Feb 20. PMID:
36845666
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Andrographis
,
Andrographolide
Diseases
:
Degenerative Disk Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Anti-apoptotic and anti-inflammatory effects of an ethanolic extract of Lycium chinense root against particulate matter 10-induced cell death and inflammation.
Sep 21, 2022
Click here to read the entire abstract
Article Publish Status
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Pubmed Data
: Plants (Basel). 2022 Sep 22 ;11(19). Epub 2022 Sep 22. PMID:
36235350
Article Published Date
: Sep 21, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Goji
Diseases
:
Air Pollution Linked Toxicity
,
Inflammation
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory activity of carvacrol protects the heart from lipopolysaccharide-induced cardiac dysfunction.
Jun 30, 2023
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2023 Jul 1 ;324:121743. Epub 2023 Apr 27. PMID:
37120013
Article Published Date
: Jun 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-18 down-regulation
,
Interleukin-1 beta downregulation
[+]
Astaxanthin attenuated cigarette smoke extract-induced apoptosis via decreasing oxidative DNA damage in airway epithelium.
Sep 09, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Biomed Pharmacother. 2023 Sep 10 ;167:115471. Epub 2023 Sep 10. PMID:
37699317
Article Published Date
: Sep 09, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
DNA damage
,
Oxidative Stress
,
Smoking
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Astragaloside IV ameliorates peritoneal fibrosis.
Jul 25, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Cell Mol Med. 2023 Jul 26. Epub 2023 Jul 26. PMID:
37494130
Article Published Date
: Jul 25, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Fibrosis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
[+]
Astragaloside IV induces the protective effect of bone marrow mesenchymal stem cells derived exosomes in acute myocardial infarction.
Mar 26, 2023
Click here to read the entire abstract
Pubmed Data
: Biotechnol Genet Eng Rev. 2023 Mar 27:1-18. Epub 2023 Mar 27. PMID:
36971224
Article Published Date
: Mar 26, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Angiogenesis Inducing Agents
,
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Berberine ameliorate inflammation and apoptosis via modulating PI3K/AKT/NFκB and MAPK pathway on dry eye.
Sep 17, 2023
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2023 Sep 18 ;121:155081. Epub 2023 Sep 18. PMID:
37748390
Article Published Date
: Sep 17, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Dry Eye Syndromes
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Bilobalide prevents ischemia-induced edema formation in vitro and in vivo.
Jan 04, 2007
Click here to read the entire abstract
Pubmed Data
: Neuroscience. 2007 Jan 5 ;144(1):217-22. Epub 2006 Oct 2. PMID:
17014966
Article Published Date
: Jan 04, 2007
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Brain Ischemia
,
Stroke
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Brain-targeted ginkgolide B-modified carbonized polymer dots for alleviating cerebral ischemia reperfusion injury.
May 29, 2023
Click here to read the entire abstract
Pubmed Data
: Biomater Sci. 2023 May 30 ;11(11):3998-4008. Epub 2023 May 30. PMID:
37128751
Article Published Date
: May 29, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Ellagic acid improves benign prostate hyperplasia.
Jun 16, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Death Dis. 2022 Jun 17 ;13(6):554. Epub 2022 Jun 17. PMID:
35715415
Article Published Date
: Jun 16, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Prostatic Hyperplasia: Benign
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Erinacine A prevents lipopolysaccharide-mediated glial cell activation to protect dopaminergic neurons against inflammatory factor-induced cell death.
Jan 11, 2022
Click here to read the entire abstract
Pubmed Data
: Int J Mol Sci. 2022 Jan 12 ;23(2). Epub 2022 Jan 12. PMID:
35054997
Article Published Date
: Jan 11, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lion's Mane (Hericium Erinaceus)
Diseases
:
Brain Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Neurodegenerative Diseases
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Ferulic acid ameliorates acetaminophen-induced acute liver injury.
May 04, 2022
Click here to read the entire abstract
Pubmed Data
: IUBMB Life. 2022 May 5. Epub 2022 May 5. PMID:
35514074
Article Published Date
: May 04, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ferulic acid
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Ferulic acid attenuates high glucose-induced apoptosis in retinal pigment epithelium cells.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PeerJ. 2022 ;10:e13375. Epub 2022 May 31. PMID:
35669949
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ferulic acid
Diseases
:
Diabetic Retinopathy
Pharmacological Actions
:
Anti-Apoptotic
[+]
Fisetin attenuates doxorubicin-induced cardiotoxicity.
Apr 25, 2023
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2023 Apr 26. Epub 2023 Apr 26. PMID:
37186468
Article Published Date
: Apr 25, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Fisetin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Fucoidan inhibits apoptosis and improves cardiac remodeling.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Front Pharmacol. 2023 ;14:1164333. Epub 2023 May 30. PMID:
37324479
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Heart Failure
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
,
SIRT1 Activator
[+]
Genistein attenuates memory impairment in Alzheimer's disease.
Aug 02, 2022
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2022 Aug 3 ;109:109118. Epub 2022 Aug 3. PMID:
35933022
Article Published Date
: Aug 02, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Genistein
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Geraniol-mediated suppression of endoplasmic reticulum stress protects against cerebral ischemia-reperfusion injury.
Dec 28, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2022 Dec 29 ;24(1). Epub 2022 Dec 29. PMID:
36613992
Article Published Date
: Dec 28, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Geraniol
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Ginger efficiently reduced the lung damage and protected the lungs from severe damage due to hyperoxia and inflammation.
Aug 15, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Turk J Med Sci. 2018 Aug 16 ;48(4):892-900. Epub 2018 Aug 16. PMID:
30121057
Article Published Date
: Aug 15, 2018
Study Type
: Human: Case Report
Additional Links
Substances
:
Ginger
Diseases
:
Bronchopulmonary Dysplasia
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Ginkgolide B exerts cardioprotective properties against doxorubicin-induced cardiotoxicity.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(12):e0168219. Epub 2016 Dec 14. PMID:
27973574
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
Additional Keywords
:
Drug: Doxorubicin
[+]
Ginsenosides CK as a potential therapeutic approach for treating muscle-wasting conditions associated with obesity.
Apr 30, 2022
Click here to read the entire abstract
Pubmed Data
: J Ginseng Res. 2022 May ;46(3):444-453. Epub 2021 Sep 10. PMID:
35600773
Article Published Date
: Apr 30, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Obesity
,
Sarcopenia
Pharmacological Actions
:
Anti-Apoptotic
[+]
Glabridin attenuates the retinal degeneration.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2020 ;11:566699. Epub 2020 Oct 15. PMID:
33178017
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Macular Degeneration
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
In vitro and in vivo nephroprotective effects of Nelumbo nucifera seedpod extract against cisplatin-induced renal injury.
Dec 01, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Plants (Basel). 2022 Dec 2 ;11(23). Epub 2022 Dec 2. PMID:
36501396
Article Published Date
: Dec 01, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Lotus
Diseases
:
Chemotherapy-Induced Kidney Damage
,
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Chemoprotective Agents
,
Renoprotective
[+]
Isorhamnetin alleviates lipopolysaccharide-induced acute lung injury.
May 31, 2022
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2022 Jun ;44(3):387-399. Epub 2022 Mar 21. PMID:
35306954
Article Published Date
: May 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Lung Injury: Acute
Pharmacological Actions
:
Anti-Apoptotic
,
Autophagy Up-regulation
,
NF-kappaB Inhibitor
[+]
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress.
Jan 31, 2022
Click here to read the entire abstract
Pubmed Data
: Free Radic Res. 2022 Feb ;56(2):209-221. Epub 2022 Apr 25. PMID:
35468014
Article Published Date
: Jan 31, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Luteolin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Multi-target effects of ß-caryophyllene and carnosic acid at the crossroads of mitochondrial dysfunction and neurodegeneration.
Jun 17, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Antioxidants (Basel). 2022 Jun 18 ;11(6). Epub 2022 Jun 18. PMID:
35740096
Article Published Date
: Jun 17, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Beta-Caryophyllene
,
Carnosic Acid
Diseases
:
Alzheimer's Disease
,
Brain: Oxidative Stress
,
Brain Inflammation
,
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
,
Nrf2 activation
[+]
Myricetin improves apoptosis after ischemic stroke via inhibiting MAPK-ERK pathway.
Jan 07, 2023
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2023 Jan 8. Epub 2023 Jan 8. PMID:
36611117
Article Published Date
: Jan 07, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Myricetin
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Neuroprotective effects of a new triterpenoid from edible mushroom on oxidative stress and apoptosis.
Nov 27, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Nov 28 ;13(23):12121-12134. Epub 2022 Nov 28. PMID:
36321740
Article Published Date
: Nov 27, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Chaga Mushroom (Inonotus obliquus)
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Panax notoginseng saponins inhibits oxidative stress- induced human nucleus pulposus cell apoptosis and delays disc degeneration.
Sep 14, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: J Ethnopharmacol. 2023 Sep 15 ;319(Pt 1):117166. Epub 2023 Sep 15. PMID:
37716491
Article Published Date
: Sep 14, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Panax Notoginseng
Diseases
:
Degenerative Disk Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Autophagy Inhibitors
[+]
Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis‑fibroblast‑like synoviocytes.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2022 05 ;25(5). Epub 2022 Mar 24. PMID:
35322865
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Piceatannol
Diseases
:
Inflammation
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
NF-kappaB Inhibitor
[+]
Procyanidin B2 ameliorates the progression of osteoarthritis.
Oct 19, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int Immunopharmacol. 2022 Oct 20 ;113(Pt A):109336. Epub 2022 Oct 20. PMID:
36274486
Article Published Date
: Oct 19, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Procyanidin B2
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Osteoprotective
[+]
Protective effect of hydroxysafflor yellow A on cyclosporin A-induced renal oxidative stress.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Cir Bras. 2022 ;37(3):e370305. Epub 2022 Jun 15. PMID:
35730865
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Safflower
Diseases
:
Kidney Damage: Chemically-Induced
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Renoprotective
,
Superoxide Dismutase Up-regulation
[+]
Protective mechanisms of 10-gingerol against myocardial ischemia.
Jun 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2022 Jul ;151:113082. Epub 2022 May 12. PMID:
35569350
Article Published Date
: Jun 30, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginger
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Sinensetin reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2021 ;12:713491. Epub 2021 Jul 16. PMID:
34335275
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Osteoprotective
[+]
Synergistic effects of ginkgolide B and protocatechuic acid on the treatment of Parkinson's disease.
Aug 30, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 Aug 31 ;25(17). Epub 2020 Aug 31. PMID:
32878312
Article Published Date
: Aug 30, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
Additional Keywords
:
Natural Substance Synergy
[+]
Taxifolin prevents diabetic cardiomyopathy in vivo and in vitro by inhibition of oxidative stress and cell apoptosis.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2014 Jan ;63:221-32. Epub 2013 Nov 20. PMID:
24269735
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cardiomyopathy
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Tilianin protects against ischemia/reperfusion-induced myocardial injury.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2020 ;2020:5939715. Epub 2020 Oct 9. PMID:
33102583
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cardioprotective
,
NF-kappaB Inhibitor
[+]
Wogonin attenuates neutrophilic inflammation and airway smooth muscle proliferation.
Nov 10, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int Immunopharmacol. 2022 Nov 11 ;113(Pt B):109410. Epub 2022 Nov 11. PMID:
36371864
Article Published Date
: Nov 10, 2022
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Wogonin
Diseases
:
Asthma
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Wolfberry water extract attenuates blue light-emitting diode damage to ARPE-19 cells and mouse retina.
Apr 30, 2023
Click here to read the entire abstract
Pubmed Data
: J Food Sci. 2023 May ;88(5):2229-2245. Epub 2023 Apr 6. PMID:
37025094
Article Published Date
: Apr 30, 2023
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Goji
Diseases
:
Blue Light Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Photoprotective
Anti Therapeutic Actions
:
Blue Light (400−495 nm)
[+]
Effect of oleuropein on oxidative stress, inflammation and apoptosis induced by ischemia-reperfusion injury in rat kidney.
Aug 14, 2020
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2020 Aug 15 ;255:117833. Epub 2020 May 22. PMID:
32450167
Article Published Date
: Aug 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Oleuropein
Diseases
:
Inflammation
,
Ischemia
,
Kidney Damage
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
[+]
Emodin promotes fibroblast apoptosis and prevents epidural fibrosis through PERK pathway in rats.
Oct 09, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Orthop Surg Res. 2019 Oct 10 ;14(1):319. Epub 2019 Oct 10. PMID:
31601256
Article Published Date
: Oct 09, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Emodin
Diseases
:
Fibrosis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
[+]
Genistein attenuates cognitive deficits and neuroapoptosis in hippocampus induced by ketamine exposure.
Jul 07, 2020
Click here to read the entire abstract
Pubmed Data
: Synapse. 2020 Jul 8:e22181. Epub 2020 Jul 8. PMID:
32639628
Article Published Date
: Jul 07, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Genistein
Diseases
:
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Neuroprotective effect of chrysin on isoniazid-induced neurotoxicity via suppression of oxidative stress, inflammation and apoptosis in rats
Nov 30, 2020
Click here to read the entire abstract
Pubmed Data
: Neurotoxicology. 2020 Dec ;81:197-208. Epub 2020 Oct 26. PMID:
33121995
Article Published Date
: Nov 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Isoniazid
[+]
Pycnogenol achieves neuroprotective effects in rats with spinal cord injury by stabilizing the mitochondrial membrane potential.
Jun 30, 2020
Click here to read the entire abstract
Pubmed Data
: Neurol Res. 2020 Jul ;42(7):597-604. Epub 2020 Jun 4. PMID:
32497471
Article Published Date
: Jun 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Pycnogenol (Pine Bark)
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Red ginseng oil promotes hair growth and protects skin against UVC radiation.
Jun 30, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2021 Jul ;45(4):498-509. Epub 2021 Jan 16. PMID:
34295210
Article Published Date
: Jun 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng
Diseases
:
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Photoprotective
Additional Keywords
:
Hair Regeneration
[+]
Salvia miltiorrhiza polysaccharides alleviates florfenicol induced kidney injury in chicks via inhibiting oxidative stress and apoptosis
Feb 22, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ecotoxicol Environ Saf. 2022 Feb 23 ;233:113339. Epub 2022 Feb 23. PMID:
35219255
Article Published Date
: Feb 22, 2022
Study Type
: Animal Study
Additional Links
Diseases
:
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
Additional Keywords
:
Polysaccharides
[+]
These findings indicate a novel role for naringin in protecting against fructose-induced cardiac hypertrophy.
Jun 20, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2018 Jun 21 ;8(1):9464. Epub 2018 Jun 21. PMID:
29930336
Article Published Date
: Jun 20, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Citrus naringin
Diseases
:
Cardiac Hypertrophy
,
High Fructose Diet
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
"Apoptosis inhibition of capsaicin on myocardial ischemia-reperfusion injury in rats"
Feb 28, 2011
Click here to read the entire abstract
Pubmed Data
: Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Mar ;42(2):218-21. PMID:
21500557
Article Published Date
: Feb 28, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Capsaicin
Diseases
:
Myocardial Infarction
,
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside protects murine hearts against ischemia/reperfusion injury.
Feb 28, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Acta Pharmacol Sin. 2017 Mar ;38(3):317-330. Epub 2017 Jan 23. PMID:
28112174
Article Published Date
: Feb 28, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
20(R)-Ginsenoside Rg3 protects SH-SY5Y cells against apoptosis induced by oxygen and glucose deprivation/reperfusion.
Jan 14, 2017
Click here to read the entire abstract
Pubmed Data
: Bioorg Med Chem Lett. 2017 08 15 ;27(16):3867-3871. Epub 2017 Jun 19. PMID:
28709827
Article Published Date
: Jan 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
20(S)-ginsenoside Rg(3) showed the significant protective effects on cyclophosphamide-induced cell DNA damage and apoptosis.
Jan 31, 2008
Click here to read the entire abstract
Pubmed Data
: Arch Toxicol. 2008 Feb ;82(2):117-23. Epub 2007 Jun 28. PMID:
17598087
Article Published Date
: Jan 31, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
6-gingerol attenuates subarachnoid hemorrhage-induced early brain injury.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:882121. Epub 2022 Aug 25. PMID:
36091803
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Subarachnoid hemorrhage
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
6-gingerol inhibits apoptosis to attenuate myocardial ischemia/reperfusion injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2018 ;2018:9024034. Epub 2018 Mar 20. PMID:
29743926
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
6-Gingerol relieves myocardial ischaemia/reperfusion injury.
Mar 22, 2021
Click here to read the entire abstract
Pubmed Data
: Lab Invest. 2021 Mar 23. Epub 2021 Mar 23. PMID:
33758383
Article Published Date
: Mar 22, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
,
MicroRNA modulator
[+]
6-shogaol from dried ginger protects against intestinal ischemia/reperfusion.
Jun 30, 2023
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2023 Jul ;67(13):e2200773. Epub 2023 May 14. PMID:
37118920
Article Published Date
: Jun 30, 2023
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
,
Ginger
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
6-Shogaol protects against isoproterenol-induced cardiac injury.
Nov 30, 2022
Click here to read the entire abstract
Pubmed Data
: J Physiol Pharmacol. 2022 Dec ;73(6). Epub 2023 Apr 17. PMID:
37087565
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
A combination of chamomile and oregano extracts could form a new class of drugs to treat diabetic complications.
Sep 01, 2016
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2016 Sep 2:1-9. Epub 2016 Sep 2. PMID:
27875075
Article Published Date
: Sep 01, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Chamomile
,
Oregano
Diseases
:
Diabetic Complications
Pharmacological Actions
:
Alpha-amylase inhibitor
,
Anti-Apoptotic
,
Hypoglycemic Agents
,
Hypolipidemic
Additional Keywords
:
Natural Substance Synergy
,
Plant Extracts
Problem Substances
:
Alloxan
[+]
A lipid peroxidation product of DHA regulates mitochondrial homeostasis and reduces apoptosis to reduce reperfusion damage in a rat model of ischemic reperfusion.
Jan 01, 2017
Click here to read the entire abstract
Pubmed Data
: Free Radic Biol Med. 2017 01 ;102:229-239. Epub 2016 Dec 5. PMID:
27932075
Article Published Date
: Jan 01, 2017
Study Type
: Animal Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
,
Omega-3 Fatty Acids
Diseases
:
Myocardial Infarction
,
Tachycardia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
Additional Keywords
:
Cardiovascular Activity
,
Lipid Peroxidation
,
Mitochondria
,
Omega-3 Fatty Acid Metabolism
[+]
A mechanistic insight into the potential anti-cancerous property of Nigella sativa on breast cancer.
Aug 31, 2023
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2023 Sep ;169:105601. Epub 2023 Jul 3. PMID:
37406886
Article Published Date
: Aug 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-Apoptotic
,
MicroRNA modulator
Additional Keywords
:
Plant Extracts
[+]
A methanolic extract of Piper nigrum ameliorates beta-amyloid (1–42)-induced anxiety and depression by attenuation of the oxidative stress in the rat amygdala.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Behav Brain Funct. 2015 ;11:13. Epub 2015 Mar 29. PMID:
25880991
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Black Pepper
Diseases
:
Alzheimer's Disease
,
Anxiety Disorders
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Anxiolytic
,
Neuroprotective Agents
Additional Keywords
:
Plant Extracts
[+]
A mixture of curcumin, hesperidin and rutin ameliorates hepatic oxidative stress caused by STZ-induced hyperglycemia.
Aug 11, 2015
Click here to read the entire abstract
Pubmed Data
: Curr Neurovasc Res. 2015 Aug 12. Epub 2015 Aug 12. PMID:
26265154
Article Published Date
: Aug 11, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Hesperidin
,
Rutin
Diseases
:
Diabetes Mellitus: Type 2
,
Hyperglycemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
Hypoglycemic Agents
,
Hypolipidemic
,
Superoxide Dismutase Up-regulation
[+]
A standardized extract of neem has neuroprotective effects in partial sciatic nerve injury.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: EXCLI J. 2017 ;16:546-565. Epub 2017 Apr 18. PMID:
28694757
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Neem
Diseases
:
Nerve Injuries
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Neuroprotective Agents
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A. paniculata extract can be used for prevention and treatment of cardiovascular disease in obese patients.
Nov 03, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Nov 4 ;192:170-177. Epub 2016 Jul 9. PMID:
27401291
Article Published Date
: Nov 03, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Cardiac Hypertrophy
,
High Fat Diet
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cardioprotective
,
Cyclooxygenase 2 Inhibitors
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Acacetin alleviates myocardial ischaemia/reperfusion injury.
Nov 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2022 Dec ;60(1):553-561. PMID:
35244510
Article Published Date
: Nov 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Myocardial Ischemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Bcl-2 protein down-regulation
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
[+]
Acacetin ameliorates cardiac hypertrophy by activating Sirt1/AMPK/PGC-1α pathway.
Apr 04, 2022
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2022 Apr 5 ;920:174858. Epub 2022 Feb 24. PMID:
35219729
Article Published Date
: Apr 04, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Cardiac Hypertrophy
,
Cardiomegaly
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
,
Nrf2 activation
[+]
Acacetin attenuates renal damage-induced by ischemia-reperfusion.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Prev Med. 2020 ;11:22. Epub 2020 Feb 17. PMID:
32175062
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Renoprotective
[+]
Acacetin inhibits myocardial mitochondrial dysfunction.
Feb 28, 2023
Click here to read the entire abstract
Pubmed Data
: J Nat Med. 2023 Mar ;77(2):262-275. Epub 2022 Dec 15. PMID:
36520340
Article Published Date
: Feb 28, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Hypertension
,
Insulin Resistance
,
Mitochondrial Dysfunction
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Acacetin protects against cardiac remodeling after myocardial infarction.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharmacol Sci. 2017 Dec ;135(4):156-163. Epub 2017 Dec 1. PMID:
29276114
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Acacetin suppresses IL-1 β-induced expression of matrix metalloproteinases in chondrocytes and protects against osteoarthritis.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2020 ;2020:2328401. Epub 2020 Oct 26. PMID:
33195691
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
NF-kappaB Inhibitor
[+]
Acetyl-11-keto-beta-boswellic acid is a promising therapeutic agent to promote sciatic nerve repair by alleviating excessive oxidative stress.
Aug 22, 2023
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2023 Aug 23. Epub 2023 Aug 23. PMID:
37541437
Article Published Date
: Aug 22, 2023
Study Type
: Animal Study
Additional Links
Substances
:
acetyl-11-keto-beta-boswellic acid
Diseases
:
Sciatic Nerve Crush Injury
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Nrf2 activation
Additional Keywords
:
Nerve Regeneration
[+]
Acupuncture may improve neurological function, reduce cerebral infarction volume and prolong the time window of thrombolysis.
Mar 24, 2020
Click here to read the entire abstract
Pubmed Data
: Zhen Ci Yan Jiu. 2020 Mar 25 ;45(3):209-14. PMID:
32202712
Article Published Date
: Mar 24, 2020
Study Type
: Animal Study
Additional Links
Diseases
:
Cerebral Ischemia
,
Stroke
Therapeutic Actions
:
Acupuncture
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Administration of bergamot juice potentially may be beneficial for the treatment of inflammatory bowel disease in humans.
Nov 26, 2014
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2014 Nov 27. Epub 2014 Nov 27. PMID:
25491246
Article Published Date
: Nov 26, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Bergamot orange
Diseases
:
Inflammatory Bowel Diseases
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
[+]
Administration of deep sea minerals can be an effective strategy to improve the life expectancy of diabetic subjects.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2016 Jul ;31(7):769-81. Epub 2015 Mar 2. PMID:
25727812
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Water: Deep Sea
Diseases
:
Diabetic Complications
,
Heart Failure
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
Additional Keywords
:
Anti-Apoptotic
,
Cardioprotective
,
Diabetic Complications
,
Heart Failure
,
Water: Deep Sea
[+]
Administration of medicinal mushrooms under experimental diabetes showed a positive corrective action on the L-arginine/NO system and the ratio between p53 and Bcl-2 proteins.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Int J Med Mushrooms. 2015 ;17(4):339-50. PMID:
25954960
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Agaricus brasiliensis
,
Medicinal Mushrooms
,
Reishi Mushroom
Diseases
:
Diabetes Mellitus: Type 1
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Nitric Oxide Inhibitor
[+]
Administration of N- acetylcysteine and genistein have an additive gastroprotective effect in indomethacin induced gastric injury.
Jul 15, 2018
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2018 Jul 16. Epub 2018 Jul 16. PMID:
30011378
Article Published Date
: Jul 15, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
,
Genistein
Diseases
:
Drug-Induced Toxicity: Indomethacin
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Gastroprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Administration of naringenin to propofol-exposed mice resulted in significant neuroprotective effects.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Drug Des Devel Ther. 2020 ;14:5469-5482. Epub 2020 Dec 10. PMID:
33328725
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Naringenin
Diseases
:
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Neuroprotective Agents
[+]
Administration of Nigella sativa can be used to prevent formaldehyde induced apoptosis and epithelial damage.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Niger J Clin Pract. 2017 May ;20(5):523-529. PMID:
28513508
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Formaldehyde Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Cytoprotective
Problem Substances
:
Formaldehyde
[+]
Administration of palmitoylethanolamide protects the neurovascular unit and reduces secondary injury after traumatic brain injury.
Oct 31, 2012
Click here to read the entire abstract
Pubmed Data
: Brain Behav Immun. 2012 Nov ;26(8):1310-21. Epub 2012 Aug 3. PMID:
22884901
Article Published Date
: Oct 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Palmitoylethanolamide
Diseases
:
Brain Injury: Traumatic
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Administration of parsley oil either as a preventative medicine or as treatment significantly improved cisplatin-induced hepato-cardiotoxicity.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Feb ;86:482-491. Epub 2016 Dec 23. PMID:
28012928
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Parsley
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
Additional Keywords
:
Plant Oils
[+]
Agaricus blazei Murill polysaccharides inhibited cadmium induced effects on chicken peripheral blood lymphocytes.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2017 Nov ;180(1):153-163. Epub 2017 Mar 10. PMID:
28283953
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Agaricus Blazei
Diseases
:
Cadmium Poisoning
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
Problem Substances
:
Cadmium
[+]
AGE has an ameliorative effect against CP-induced oxidative stress and renal damage through its antioxidant, anti-inflammatory and antiapoptotic properties.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Cell Int. 2014 ;14(1):92. Epub 2014 Sep 28. PMID:
25298749
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Chemoprotective Agents
,
Renoprotective
Additional Keywords
:
Plant Extracts
[+]
Aged garlic extract attenuates neuronal injury in a rat model of spinal cord ischemia/reperfusion injury.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2016 Jun ;19(6):601-6. Epub 2016 May 16. PMID:
27183321
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Ischemia
,
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Ajwa date extract afforded significant protection against carbon tetrachloride-induced hepatocellular injury.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2017 Nov ;30(6):2183-2191. PMID:
29175788
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Dates
Diseases
:
Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
[+]
Ajwa' dates extract ameliorates isoproterenol-induced cardiomyopathy.
Oct 14, 2016
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2016 Oct 15 ;23(11):1240-8. Epub 2015 Dec 14. PMID:
26776662
Article Published Date
: Oct 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Dates
Diseases
:
Cardiomyopathy
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cardioprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Isoproterenol
[+]
Albiflorin attenuates high glucose-induced endothelial apoptosis via suppressing PARP1/NF-κB signaling pathway.
Nov 09, 2022
Click here to read the entire abstract
Pubmed Data
: Inflamm Res. 2022 Nov 10. Epub 2022 Nov 10. PMID:
36357814
Article Published Date
: Nov 09, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Peony
Diseases
:
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alleviating chronic kidney disease progression through modulating the critical genus of gut microbiota in a cisplatin-induced Lanyu pig model.
Dec 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Food Drug Anal. 2020 Jan ;28(1):103-114. Epub 2019 Oct 17. PMID:
31883598
Article Published Date
: Dec 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus paracasei
,
Lactobacillus plantarum
,
Probiotics
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Chronic Kidney Disease (CKD)
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Chemoprotective Agents
,
Renoprotective
[+]
Alleviating impact of hydroethanolic Murraya koenigii leaves extract on bisphenol A instigated testicular lethality and apoptosis.
Jan 07, 2020
Click here to read the entire abstract
Pubmed Data
: Andrologia. 2020 Jan 8:e13504. Epub 2020 Jan 8. PMID:
31912924
Article Published Date
: Jan 07, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Curry Tree
Diseases
:
Bisphenol Toxicity
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
Problem Substances
:
Bisphenol A
[+]
Alleviation of lead acetate-induced nephrotoxicity by Moringa oleifera extract.
Jun 11, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2020 Jun 12. Epub 2020 Jun 12. PMID:
32529628
Article Published Date
: Jun 11, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Kidney Damage: Chemically-Induced
,
Lead Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Renoprotective
Problem Substances
:
Lead
[+]
Alleviative effects of 20(R)-Rg3 on HFD/STZ-induced diabetic nephropathy.
Feb 28, 2021
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2021 Mar 1 ;267:113500. Epub 2020 Oct 19. PMID:
33091499
Article Published Date
: Feb 28, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hypoglycemic Agents
,
NF-kappaB Inhibitor
[+]
Alleviative effects of pinostrobin against cadmium-induced renal toxicity.
Dec 31, 2022
Click here to read the entire abstract
Pubmed Data
: Front Nutr. 2023 ;10:1175008. Epub 2023 May 24. PMID:
37342552
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Kidney Damage: Chemically-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Renoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Cadmium
[+]
Allicin can reduce oxidative stress damage and cardiomyocyte apoptosis in a model of myocardial infarction.
Aug 11, 2020
Click here to read the entire abstract
Pubmed Data
: Pharmacology. 2020 Aug 12:1-9. Epub 2020 Aug 12. PMID:
32784309
Article Published Date
: Aug 11, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Allicin could decrease blood glucose level, improve islet structure and insulin expression, and inhibit apoptosis to reduce STZ-induced pancreatic β cell injury.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2023 ;14:1108730. Epub 2023 Feb 3. PMID:
36817124
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Diabetes Mellitus: Type 1
Pharmacological Actions
:
Anti-Apoptotic
,
Hypoglycemic Agents
,
Pancreato Protective Agents
[+]
Allicin improves cardiac function by protecting against apoptosis in rat model of myocardial infarction.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2017 Aug ;23(8):589-597. Epub 2016 Jul 13. PMID:
27412589
Article Published Date
: Jul 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
Additional Keywords
:
Allicin
,
Anti-Apoptotic
,
Cardioprotective
,
Myocardial Infarction
[+]
Allicin protects against renal ischemia-reperfusion injury by attenuating oxidative stress and apoptosis.
Nov 24, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int Urol Nephrol. 2021 Nov 25. Epub 2021 Nov 25. PMID:
34825305
Article Published Date
: Nov 24, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Renoprotective
[+]
Allicin provided cardioprotection for cardiac hypertrophy.
Nov 30, 2018
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2018 Dec 1 ;51:241-254. Epub 2018 Oct 19. PMID:
30466623
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
Diseases
:
Cardiac Hypertrophy
,
Endothelial Dysfunction
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Aloe-emodin attenuates myocardial infarction and apoptosis via up-regulating miR-133 expression.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Pharmacol Res. 2019 Aug ;146:104315. Epub 2019 Jun 14. PMID:
31207343
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Emodin
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
MicroRNA modulator
[+]
Aloe-emodin relieves zidovudine-induced injury.
Dec 31, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2021 Jan ;81:103540. Epub 2020 Nov 5. PMID:
33161113
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Emodin
Diseases
:
HIV Drug-Induced Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Aloin protects against blood-brain barrier damage after traumatic brain injury in mice.
May 31, 2020
Click here to read the entire abstract
Pubmed Data
: Neurosci Bull. 2020 Jun ;36(6):625-638. Epub 2020 Feb 25. PMID:
32100248
Article Published Date
: May 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Brain Injury: Traumatic
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Blood Brain Barrier
[+]
Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling.
Jan 20, 2021
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2021 Jan 21 ;12(2):696-705. Epub 2021 Jan 7. PMID:
33410857
Article Published Date
: Jan 20, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Alpha lipoic acid has a therapeutic role in ameliorating DOX-induced testicular damage.
Mar 31, 2021
Click here to read the entire abstract
Pubmed Data
: Andrologia. 2021 Apr ;53(3):e13990. Epub 2021 Feb 2. PMID:
33529370
Article Published Date
: Mar 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Chemoprotective Agents
[+]
Alpha lipoic acid possess protective effects against chlorpyrifos induced liver injury.
Feb 22, 2018
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2018 Feb 23 ;59:17-23. Epub 2018 Feb 23. PMID:
29500983
Article Published Date
: Feb 22, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Chlorpyrifos
,
Pesticides
[+]
Alpha-lipoic acid alleviates colistin nephrotoxicity.
Oct 27, 2020
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2020 Oct 28:960327120966043. Epub 2020 Oct 28. PMID:
33111558
Article Published Date
: Oct 27, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Kidney Damage: Antibiotic-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Renoprotective
Problem Substances
:
Antibiotics
[+]
Alpha-lipoic acid attenuates cadmium- and lead-induced neurotoxicity.
Mar 09, 2021
Click here to read the entire abstract
Pubmed Data
: Neurotox Res. 2021 Mar 10. Epub 2021 Mar 10. PMID:
33689146
Article Published Date
: Mar 09, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Heavy Metal Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
Problem Substances
:
Cadmium
,
Lead
[+]
Alpha-lipoic acid could provide a potential treatment for atherosclerosis in postmenopausal patients.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;47(6):2261-2277. Epub 2018 Jul 5. PMID:
29975924
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
Additional Keywords
:
Ovariectomy-Induced Changes
[+]
Alpha-lipoic acid may be suggested to be a prospective candidate to ameliorate Methotrexate induced oral mucositis.
Feb 14, 2017
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2017 Feb 15 ;171:51-59. Epub 2017 Jan 3. PMID:
28062278
Article Published Date
: Feb 14, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Drug Toxicity: Methotrexate
,
Oral Mucositis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Alpha-lipoic acid plays a protective role in fluoride-induced reproductive lesion.
Dec 14, 2020
Click here to read the entire abstract
Pubmed Data
: Zhonghua Yi Xue Za Zhi. 2020 Dec 15 ;100(46):3706-3711. PMID:
33342149
Article Published Date
: Dec 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Fluoride Toxicity
,
Infertility: Male
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Malondialdehyde Down-regulation
Problem Substances
:
Sodium Fluoride
[+]
Alpha-lipoic acid protects against ERS-mediated apoptosis in a cochlear cell model.
Jul 29, 2020
Click here to read the entire abstract
Pubmed Data
: Arch Biochem Biophys. 2020 Jul 30 ;688:108402. Epub 2020 May 11. PMID:
32418909
Article Published Date
: Jul 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Hearing Loss
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling.
Jan 29, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Death Dis. 2020 07 30 ;11(7):599. Epub 2020 Jul 30. PMID:
32732978
Article Published Date
: Jan 29, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Heart Failure
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Alpha-lipoic acid reduces retinal cell death in diabetic mice.
Jul 10, 2018
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2018 Jul 11. Epub 2018 Jul 11. PMID:
30017190
Article Published Date
: Jul 10, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Diabetic Retinopathy
Pharmacological Actions
:
Anti-Apoptotic
[+]
Alpha-lipoic acid treatment prior to radiation decreases the severity and duration of radiation-induced enteritis.
Mar 02, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Mar 3. Epub 2016 Mar 3. PMID:
26943777
Article Published Date
: Mar 02, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Radiation Induced Illness: Enteritis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Radioprotective
[+]
Ameliorating effect of Citrus aurantium extracts and nobiletin on β‑amyloid (1‑42)‑induced memory impairment.
Aug 08, 2019
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2019 Aug 9. Epub 2019 Aug 9. PMID:
31432129
Article Published Date
: Aug 08, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Orange
,
Nobiletin
Diseases
:
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Amelioration of PM 2.5-induced lung toxicity in rats by nutritional supplementation with biochanin A.
Sep 30, 2020
Click here to read the entire abstract
Pubmed Data
: Ecotoxicol Environ Saf. 2020 Oct 1 ;202:110878. Epub 2020 Jun 22. PMID:
32585486
Article Published Date
: Sep 30, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Air Pollution Linked Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-2 Downregulation
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Amelioration of radiation enteropathy by dietary supplementation with reduced coenzyme Q10.
Mar 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Adv Radiat Oncol. 2019 Apr-Jun;4(2):237-245. Epub 2019 Jan 31. PMID:
31011668
Article Published Date
: Mar 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Enteropathy
,
Radiation Induced Illness
Pharmacological Actions
:
Anti-Apoptotic
,
Radioprotective
[+]
Ameliorative effect of betulinic acid against zearalenone exposure triggers testicular dysfunction and oxidative stress.
Jun 14, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ecotoxicol Environ Saf. 2022 Jun 15 ;238:113561. Epub 2022 Apr 27. PMID:
35489292
Article Published Date
: Jun 14, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Betulinic acid
Diseases
:
Oxidative Stress
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Ameliorative effect of N-acetylcysteine on the testicular tissue of adult male albino rats after glyphosate-based herbicide exposure.
Feb 16, 2022
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2022 Feb 17:e22997. Epub 2022 Feb 17. PMID:
35174928
Article Published Date
: Feb 16, 2022
Study Type
: Animal Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Glyphosate Toxicity
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
Problem Substances
:
Glyphosate
[+]
Ameliorative effects of crocin on paraquat-induced oxidative stress in testis.
Nov 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Reprod Biomed (Yazd). 2019 Dec ;17(11):807-818. Epub 2019 Dec 26. PMID:
31911963
Article Published Date
: Nov 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Pesticide Toxicity
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Malondialdehyde Down-regulation
Problem Substances
:
Paraquat
[+]
Ameliorative potentials of the ethanolic extract from Lycium chinense leaf extract against diabetic cardiomyopathy.
Sep 30, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2022 Oct ;154:113583. Epub 2022 Aug 19. PMID:
35994819
Article Published Date
: Sep 30, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Goji
Diseases
:
Cardiomyopathy
,
Diabetic Complications
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
AMPK contributes to cardioprotective effects of pterostilbene against myocardial ischemia-reperfusion injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 ;46(4):1381-1397. Epub 2018 Apr 18. PMID:
29689567
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Pterostilbene
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
[+]
Amygdalin protects against acetaminophen-induced acute liver failure.
Apr 29, 2022
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2022 Apr 30 ;602:105-112. Epub 2022 Mar 3. PMID:
35259588
Article Published Date
: Apr 29, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Amygdalin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
An aqueous extract of Saudi red propolis protects against lung damage induced by methicillin resistant S aureus.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2016 Jul ;29(4):1197-207. PMID:
27393432
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Bee Propolis
Diseases
:
Methicillin-resistant Staphylococcus aureus
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cytoprotective
[+]
An ethyl acetate extract of persimmon leaves has a potent protective effect on cognitive deficits induced by Aβ in rats.
Jun 14, 2016
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2016 Jun 15 ;23(7):694-704. Epub 2016 Apr 11. PMID:
27235708
Article Published Date
: Jun 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Persimmon
Pharmacological Actions
:
Anti-Apoptotic
,
Malondialdehyde Down-regulation
,
Neuroprotective Agents
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
An extract of Fragaria ananassa had a protective effect against cadmium chloride toxicity upon the liver.
Jan 21, 2017
Click here to read the entire abstract
Pubmed Data
: Toxicol Mech Methods. 2017 Jan 22:1-27. Epub 2017 Jan 22. PMID:
28110594
Article Published Date
: Jan 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Strawberry
Diseases
:
Cadmium Poisoning
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Bcl-2 protein down-regulation
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Cadmium
[+]
Analysis of potential protective effects of caffeic acid phenethyl ester against gentamicin ototoxicity.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Basic Med Sci. 2022 Jan ;25(1):121-125. PMID:
35656452
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Chemotherapy-Induced Toxicity: Gentamicin
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Chemoprotective Agents
[+]
Andrographis paniculata leaf extract prevents thioacetamide-induced liver cirrhosis in rats.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(10):e109424. Epub 2014 Oct 3. PMID:
25280007
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cirrhosis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Andrographolide ameliorates rheumatoid arthritis.
Oct 10, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2019 Oct 11 ;20(20). Epub 2019 Oct 11. PMID:
31614480
Article Published Date
: Oct 10, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
,
Andrographolide
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Andrographolide contributes to spinal cord injury repair.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2022 ;13:949502. Epub 2022 Oct 7. PMID:
36278181
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Andrographolide
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Andrographolide prevents high glucose-induced renal tubular cell damage.
Jul 08, 2021
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2021 Jul 9 ;91:153650. Epub 2021 Jul 9. PMID:
34332282
Article Published Date
: Jul 08, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Andrographolide
Diseases
:
Diabetic Nephropathy
,
Kidney Fibrosis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
,
Renoprotective
[+]
Anethole's effects against myocardial infarction.
May 31, 2022
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2022 Jun 1 ;360:109947. Epub 2022 Apr 14. PMID:
35430261
Article Published Date
: May 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Myocardial Infarction
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
NF-kappaB Inhibitor
,
Nrf2 activation
[+]
Angelica sinensis exerts angiogenic and anti-apoptotic effects against cerebral ischemia-reperfusion injury.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2017 ;45(8):1683-1708. Epub 2017 Nov 9. PMID:
29121798
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Angelica
Diseases
:
Brain Ischemia
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-Apoptotic
,
Neuroprotective Agents
,
Vascular Endothelial Growth Factor A Inhibitor
[+]
Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2018 May ;111:1133-1139. Epub 2018 Feb 19. PMID:
29415408
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Annatto prevents retinal degeneration induced by endoplasmic reticulum stress in vitro and in vivo.
Apr 30, 2012
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2012 May ;56(5):713-24. PMID:
22648618
Article Published Date
: Apr 30, 2012
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Achiote
Diseases
:
Retinal Diseases
Pharmacological Actions
:
Anti-Apoptotic
Additional Keywords
:
Plant Extracts
[+]
Annona muricata peel extract inhibits carbohydrate metabolizing enzymes and reduces pancreatic β-cells, inflammation, and apoptosis.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2022 ;17(10):e0276984. Epub 2022 Oct 27. PMID:
36301972
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Soursop
Diseases
:
Diabetic Complications
Pharmacological Actions
:
Alpha-glucosidase inhibitor
,
Anti-Apoptotic
,
Bcl-2 protein down-regulation
,
Hypoglycemic Agents
Additional Keywords
:
Plant Extracts
,
Superiority of Natural Substances versus Drugs
[+]
Antenatal pomegranate juice rescues hypoxia-induced fetal growth restriction in pregnant mice.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: Placenta. 2018 Jun ;66:1-7. Epub 2018 Apr 16. PMID:
29884297
Article Published Date
: May 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Hypoxia
,
Pregnancy Complications
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Anthocyanin from purple sweet potato attenuates lead-induced reproductive toxicity mediated by JNK signaling pathway in male mice.
Aug 23, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ecotoxicol Environ Saf. 2021 Aug 24 ;224:112683. Epub 2021 Aug 24. PMID:
34438266
Article Published Date
: Aug 23, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Sweet Potato: Purple
Diseases
:
Lead Poisoning
,
Male Reproductive Development Abnormalities
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
Problem Substances
:
Lead
[+]
Anthocyanin rich extract of red cabbage alleviates experimentally induced myocardial infarction.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(8):e0182137. Epub 2017 Aug 1. PMID:
28763488
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Red Cabbage
Diseases
:
Myocardial Infarction
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
Additional Keywords
:
Plant Extracts
[+]
Anthocyanins from bilberry extract have strong antioxidant properties and therefore can be considered as powerful hepatoprotectives in natural products.
Jul 14, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Jul 15 ;157:168-77. Epub 2016 Jun 14. PMID:
27312419
Article Published Date
: Jul 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Bilberry
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Anthocyanins may exhibit protective effects against high glucose induced renal injury in diabetic nephropathy via antioxidant activity.
Feb 28, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2018 Mar ;41(3):1608-1618. Epub 2018 Jan 10. PMID:
29328429
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Grape Seed Extract
Diseases
:
Diabetes: Oxidative Stress
,
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Renoprotective
Additional Keywords
:
Proanthocyanidins
[+]
Anti-apoptosis and autophagy effects of melatonin protect rat chondrocytes.
Jan 11, 2021
Click here to read the entire abstract
Pubmed Data
: Cartilage. 2021 12 ;13(2_suppl):1041S-1053S. Epub 2021 Nov 15. PMID:
34775836
Article Published Date
: Jan 11, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Melatonin
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Chondroprotective
[+]
Anti-diabetic effect mediated by Ramulus mori polysaccharides.
Mar 05, 2015
Click here to read the entire abstract
Pubmed Data
: Carbohydr Polym. 2015 Mar 6 ;117:63-69. Epub 2014 Sep 28. PMID:
25498609
Article Published Date
: Mar 05, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Mulberry
Diseases
:
Hyperglycemia
Therapeutic Actions
:
Fasting/Caloric Restriction
Pharmacological Actions
:
Anti-Apoptotic
,
Hypoglycemic Agents
,
Pancreato Protective Agents
Additional Keywords
:
Polysaccharides
[+]
Anti-hypoglycemic and hepatocyte-protective effects of hyperoside against high-carbohydrate/high-fat diet and alloxan-induced diabetes.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2018 Jan ;41(1):77-86. Epub 2017 Oct 25. PMID:
29115390
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Diabetes Mellitus: Type 2
,
High Fat Diet
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
Hypoglycemic Agents
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anti-inflammatory and -apoptotic effects of a long-term herbal extract treatment on DSS-induced colitis.
Aug 10, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutr Metab (Lond). 2021 Aug 11 ;18(1):77. Epub 2021 Aug 11. PMID:
34380504
Article Published Date
: Aug 10, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Frankincense
,
Ginger
,
Turmeric
Diseases
:
Colitis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
[+]
Anti-inflammatory and anti-apoptosis activity of taraxasterol in ulcerative colitis in vitro and in vivo.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2019 Sep ;18(3):1745-1751. Epub 2019 Jul 5. PMID:
31410133
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Dandelion
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory and anti-oxidant effects of aloe vera in rats with non-alcoholic steatohepatitis.
Jul 26, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Hepatol. 2020 Jul 27 ;12(7):363-377. PMID:
32821335
Article Published Date
: Jul 26, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Anti-inflammatory, anti-apoptotic, and antioxidant actions of Middle Eastern Phoenix dactylifera extract on mercury-induced hepatotoxicity in vivo.
Jul 31, 2020
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2020 Aug ;47(8):6053-6065. Epub 2020 Jul 31. PMID:
32737827
Article Published Date
: Jul 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Dates
Diseases
:
Chemically-Induced Liver Damage
,
Mercury Poisoning
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Mercury
[+]
Anti-inflammatory, antioxidant and anti-apoptotic activity of diosmin in acetic acid-induced ulcerative colitis.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2018 Jan ;37(1):78-86. Epub 2017 Feb 23. PMID:
29187079
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Diosmin
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-osteoarthritic effects of antarctic krill oil.
Sep 27, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2023 Sep 28 ;21(10). Epub 2023 Sep 28. PMID:
37888448
Article Published Date
: Sep 27, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Krill
Diseases
:
Inflammation
,
Osteoarthritis: Knee
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Anti-oxidant effect of bergamot polyphenolic fraction counteracts doxorubicin-induced cardiomyopathy.
May 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Mol Cell Cardiol. 2018 Jun ;119:10-18. Epub 2018 Apr 12. PMID:
29654879
Article Published Date
: May 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Bergamot
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Antiamnesic and neuroprotective effects of an aqueous extract of Ziziphus jujuba.
Dec 31, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2021 ;2021:5577163. Epub 2021 Aug 10. PMID:
34422074
Article Published Date
: Dec 31, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Jujube
Diseases
:
Alzheimer's Disease
,
Cognitive Decline/Dysfunction
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Antiapoptotic and antioxidant capacity of phytochemicals from Hibiscus sabdariffa and their potential effects on monosodium glutamate-induced testicular damage.
Sep 03, 2020
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2020 Sep 4. Epub 2020 Sep 4. PMID:
32888148
Article Published Date
: Sep 03, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Hibiscus sabdariffa
Diseases
:
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
Problem Substances
:
Monosodium Glutamate (MSG)
[+]
Antiapoptotic effects of cannabidiol in an experimental model of cognitive decline induced by brain iron overload.
Sep 02, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Transl Psychiatry. 2018 Sep 3 ;8(1):176. Epub 2018 Sep 3. PMID:
30177808
Article Published Date
: Sep 02, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Cognitive Decline/Dysfunction
,
Iron Overload
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Antidiabetic activity of avocado seeds in diabetic rats via activation of PI3K/AKT signaling pathway.
Jan 20, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2022 02 21 ;12(1):2919. Epub 2022 Feb 21. PMID:
35190649
Article Published Date
: Jan 20, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Avocado
Diseases
:
Diabetes Mellitus: Type 1
,
Diabetes Mellitus: Type 2
Pharmacological Actions
:
Anti-Apoptotic
,
Hypoglycemic Agents
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Antifatigue effect of Panax notoginseng leaves fermented with microorganisms.
Dec 31, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Nutr. 2022 ;9:824525. Epub 2022 Feb 22. PMID:
35273989
Article Published Date
: Dec 31, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Fatigue
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Antioxidant and anti-apoptotic effects of royal jelly against nicotine-induced testicular injury in mice.
May 31, 2019
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2019 Jun ;34(6):708-718. Epub 2019 Mar 21. PMID:
30896085
Article Published Date
: May 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Royal Jelly
Diseases
:
Testicular Injury: Nicotine-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Antioxidant and anti-apoptotic potency of allicin and lycopene against methotrexate-induced cardiac injury.
Jul 31, 2023
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2023 Aug ;30(38):88724-88733. Epub 2023 Jul 13. PMID:
37440131
Article Published Date
: Jul 31, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Allicin
,
Lycopene
Diseases
:
Drug Toxicity: Methotrexate
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
[+]
Antioxidant and anti-inflammatory potential of thymoquinone and lycopene mitigate the chlorpyrifos-induced toxic neuropathy.
Sep 19, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmaceuticals (Basel). 2021 Sep 20 ;14(9). Epub 2021 Sep 20. PMID:
34577640
Article Published Date
: Sep 19, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene
,
Thymoquinone
Diseases
:
Pesticide Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Chlorpyrifos
[+]
Antioxidant apigenin relieves age-related muscle atrophy.
Aug 27, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Gerontol A Biol Sci Med Sci. 2020 Aug 28. Epub 2020 Aug 28. PMID:
32857105
Article Published Date
: Aug 27, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Muscle Atrophy
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-β-boswellic acid in combination on isoproterenol-induced myocardial injury.
May 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2016 Jun ;37(6):1501-10. Epub 2016 Apr 20. PMID:
27121241
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
acetyl-11-keto-beta-boswellic acid
,
Safflower
Diseases
:
Hypoxia
,
Myocardial Ischemia
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Cardioprotective
,
Malondialdehyde Down-regulation
,
Nrf2 activation
,
Superoxide Dismutase Up-regulation
[+]
Antioxidant properties of red raspberry extract alleviate hepatic fibrosis.
Oct 05, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2021 Oct 6 ;144:112284. Epub 2021 Oct 6. PMID:
34626932
Article Published Date
: Oct 05, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Raspberry
Diseases
:
Liver Fibrosis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
,
Antioxidants
[+]
Antioxidant, antiapoptotic, and anti-inflammatory effects of hesperetin.
Mar 17, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2023 Mar 18 ;28(6). Epub 2023 Mar 18. PMID:
36985731
Article Published Date
: Mar 17, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Inflammation
,
Kidney Damage
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Renoprotective
[+]
Antioxidant, antiapoptotic, and antifibrotic effects of the combination of liposomal resveratrol and carvedilol against doxorubicin-induced cardiomyopathy.
Mar 14, 2020
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2020 Mar 15:e22492. Epub 2020 Mar 15. PMID:
32173980
Article Published Date
: Mar 14, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
,
Antioxidants
,
Cardioprotective
,
Chemoprotective Agents
[+]
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
Apr 30, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 May ;46:124-132. Epub 2017 Mar 7. PMID:
28282576
Article Published Date
: Apr 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Paeonol
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Failure: Acute
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Antioxidative, anti-inflammatory and anti-apoptotic action of ellagic acid against lead acetate induced testicular and hepato-renal oxidative damages.
May 31, 2022
Click here to read the entire abstract
Pubmed Data
: Environ Pollut. 2022 Jun 1 ;302:119048. Epub 2022 Feb 24. PMID:
35219795
Article Published Date
: May 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage: Chemically-Induced
,
Oxidative Stress
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
Problem Substances
:
Lead
[+]
Antiproliferative and anti-apoptotic effect of astaxanthin in an oxygen-induced retinopathy model.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Can J Ophthalmol. 2019 Feb ;54(1):65-74. Epub 2018 Apr 11. PMID:
30851776
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Retinopathy: Hyperoxia-induced
Pharmacological Actions
:
Anti-Apoptotic
[+]
Antitumor mechanisms of an exopolysaccharide from Lactobacillus fermentum on HT-29 cells and HT-29 tumor-bearing mice.
Apr 10, 2022
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2022 Apr 11. Epub 2022 Apr 11. PMID:
35421410
Article Published Date
: Apr 10, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus fermentum
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Apoptotic
[+]
Apigenin attenuates doxorubicin induced cardiotoxicity via reducing oxidative stress and apoptosis.
Jul 03, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 Jul 4:116623. Epub 2019 Jul 4. PMID:
31279781
Article Published Date
: Jul 03, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Chemoprotective Agents
[+]
Apigenin attenuates edifenphos-induced toxicity.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: Pestic Biochem Physiol. 2019 Sep ;159:163-172. Epub 2019 Jun 24. PMID:
31400778
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Oxidative Stress
,
Pesticide-Induced Toxicity: Organophosphates
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
Renoprotective
Problem Substances
:
Organophosphate Pesticides
[+]
Apigenin increased the expression of Bcl-2 and reduced Fas/FasL expression in renal ischemia-reperfusion injury.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2017 Dec ;14(6):5345-5354. Epub 2017 Oct 2. PMID:
29285062
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Renoprotective
[+]
Apigenin possesses excellent protective effect against 3-MCPD-induced renal injury.
Dec 24, 2018
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2018 Dec 25 ;296:9-17. Epub 2018 Aug 11. PMID:
30107153
Article Published Date
: Dec 24, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Kidney Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Renoprotective
[+]
Apigenin pre-treatment can protect renal function against ischemia/reperfusion injury and prevent renal tubular cells from apoptosis.
Oct 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Ren Fail. 2018 Nov ;40(1):498-505. PMID:
30278824
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Apigenin
Diseases
:
Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Renoprotective
[+]
Apigenin protected the myocardium against simulated ischemia/reperfusion injury.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2019 ;2019:7973098. Epub 2019 Mar 20. PMID:
31015891
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Apigenin-coated gold nanoparticles as a cardioprotective strategy against doxorubicin-induced cardiotoxicity.
Feb 28, 2023
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2023 Mar ;9(3):e14024. Epub 2023 Feb 24. PMID:
36915508
Article Published Date
: Feb 28, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
,
Chemoprotective Agents
[+]
Apocynin alleviates cisplatin-induced testicular cytotoxicity.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: Andrologia. 2019 May ;51(4):e13227. Epub 2019 Jan 8. PMID:
30623469
Article Published Date
: Apr 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Apocynin
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
,
Oxidative Stress
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Chemoprotective Agents
[+]
Apocynin ameliorates diabetic retinopathy in rats: Involvement of TLR4/NF-κB signaling pathway.
Jul 31, 2019
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2019 Aug ;73:49-56. Epub 2019 May 9. PMID:
31078925
Article Published Date
: Jul 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Apocynin
Diseases
:
Diabetic Retinopathy
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
[+]
Apocynin attenuates methotrexate-induced mucositis.
Feb 28, 2023
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2023 Mar ;36(2):457-466. PMID:
37530153
Article Published Date
: Feb 28, 2023
Study Type
: Animal Study
Additional Links
Substances
:
Apocynin
Diseases
:
Drug Toxicity: Methotrexate
,
Mucositis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Apple extracts can extend cellular lifespan by lowering the level of intracellular ROS and by the activation of cellular signalling pathways.
Apr 04, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2017 Apr 5 ;17(1):200. Epub 2017 Apr 5. PMID:
28381226
Article Published Date
: Apr 04, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apple
,
Apple Polyphenols
Diseases
:
Aging
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Apple intake, specifically boiled apple, might reduce the risk of coronary heart disease by inhibiting postocclusion steps, such as myocardial injury after artery occlusion.
Oct 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Res. 2014 Nov ;34(11):951-60. Epub 2014 Aug 27. PMID:
25304826
Article Published Date
: Oct 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Apple
Diseases
:
Atherosclerosis
,
Cardiovascular Diseases
,
Myocardial Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-atherogenic
,
Cardioprotective
Additional Keywords
:
Plant Extracts
[+]
Apple phenolic extracts ameliorate lead-induced cognitive impairment and depression- and anxiety-like behavior.
Feb 14, 2022
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2022 Feb 15. Epub 2022 Feb 15. PMID:
35167638
Article Published Date
: Feb 14, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Apple
Diseases
:
Anxiety
,
Cognitive Decline/Dysfunction
,
Depression
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
MicroRNA modulator
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Lead
[+]
Apple polyphenols extract alleviated dextran sulfate sodium induced acute ulcerative colitis.
Nov 04, 2021
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Foods. 2021 Nov 5 ;10(11). Epub 2021 Nov 5. PMID:
34828992
Article Published Date
: Nov 04, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
Diseases
:
Brain Inflammation
,
Ulcerative Colitis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Apricot supplementation and irradiation given in combination, offer maximum protection against DMBA-induced hepatic carcinogenesis.
Jul 31, 2014
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2014 Aug ;70:128-33. Epub 2014 May 10. PMID:
24819963
Article Published Date
: Jul 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Apricot
Diseases
:
Chemically-Induced Liver Damage
,
Chemotherapy and Radiation Toxicity
,
Liver Cancer
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anticarcinogenic Agents
,
NF-kappaB Inhibitor
[+]
Arctigenin ameliorates renal impairment and inhibits endoplasmic reticulum stress in diabetic db/db mice.
Apr 14, 2019
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2019 Apr 15 ;223:194-201. Epub 2019 Mar 18. PMID:
30898648
Article Published Date
: Apr 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Diabetic Nephropathy
Pharmacological Actions
:
Anti-Apoptotic
,
Hypoglycemic Agents
[+]
Arctigenin might exert great therapeutic potential in immune-mediated liver injury.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Immunol. 2018 ;9:1881. Epub 2018 Aug 16. PMID:
30177931
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions
:
Anti-Apoptotic
,
Autophagy Inhibitors
,
Hepatoprotective
Problem Substances
:
Concanavalin A
[+]
Arctium lappa could be considered a potentially valuable medicinal food for dry age-related macular degeneration.
Apr 08, 2020
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2020 Apr 9 ;25(7). Epub 2020 Apr 9. PMID:
32283798
Article Published Date
: Apr 08, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Burdock
Diseases
:
Macular Degeneration
Pharmacological Actions
:
Anti-Apoptotic
[+]
Arctium lappa L. roots protect against cerebral ischemia through inhibiting apoptosis and AMPK/mTOR-mediated autophagy.
Feb 20, 2021
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2021 Feb 21 ;85:153526. Epub 2021 Feb 21. PMID:
33691269
Article Published Date
: Feb 20, 2021
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Burdock
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Apoptotic
,
Autophagy Up-regulation
,
Neuroprotective Agents
[+]
Artesunate ameliorates sepsis-induced acute lung injury.
Jul 22, 2020
Click here to read the entire abstract
Pubmed Data
: Gene. 2020 Jul 23:144969. Epub 2020 Jul 23. PMID:
32712064
Article Published Date
: Jul 22, 2020
Study Type
: Animal Study
Additional Links
Substances
:
Artesunate
Diseases
:
Lung Injury: Acute
,
Sepsis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
[+]
Artesunate may be of value as a therapeutic agent for osteoarthritis.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2019 Oct ;44(4):1541-1551. Epub 2019 Jul 26. PMID:
31364719
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Artesunate
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]
Artesunate mitigated hyperglycemia-induced nerve injury.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2023 ;46(6):764-772. PMID:
37258141
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Artesunate
Diseases
:
Peripheral Neuropathies
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Artificial tears containing epigallocatechin gallate and hyaluronic acid had a synergistic effect in the treatment of dry eye syndrome.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016;11(6):e0157982. Epub 2016 Jun 23. PMID:
27336157
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Dry Eye Syndromes
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Natural Substance Synergy
[+]
Ascorbic acid protects male rat brain from oral potassium dichromate-induced oxdative DNA damage and apoptotic changes
Feb 25, 2018
Click here to read the entire abstract
Pubmed Data
: Environ Sci Pollut Res Int. 2018 Feb 26. Epub 2018 Feb 26. PMID:
29484617
Article Published Date
: Feb 25, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
DNA damage
Pharmacological Actions
:
Anti-Apoptotic
,
Neuroprotective Agents
[+]
Ascorbic acid reduced the frequency and severity of renal injury in this murine model of contrast induced nephropathy.
Mar 23, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Nephrol. 2017 Mar 24 ;18(1):101. Epub 2017 Mar 24. PMID:
28340561
Article Published Date
: Mar 23, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Nephropathy
Pharmacological Actions
:
Anti-Apoptotic
,
Renoprotective
[+]
Ashwagandha may serve as an effective dietary supplement for management of sleep deprivation induced stress and associated functional impairments.
Dec 20, 2016
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2016 Dec 21. Epub 2016 Dec 21. PMID:
28004351
Article Published Date
: Dec 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ashwagandha
Diseases
:
Brain Inflammation
,
Insomnia
,
Sleep Disorders
Pharmacological Actions
:
Anti-Anxiety Agents
,
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Asiatic acid attenuates high-fat diet-induced impaired spermatogenesis.
Feb 28, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2018 Mar ;15(3):2397-2403. Epub 2017 Dec 22. PMID:
29467846
Article Published Date
: Feb 28, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
High Fat Diet
,
Testicular Injury: Chemical/Metal Induced
Pharmacological Actions
:
Anti-Apoptotic
[+]
Asiatic acid could be able to modulate various pathological features of Alzheimer's disease and could hold promise in its treatment.
Jan 21, 2019
Click here to read the entire abstract
Pubmed Data
: Neurotox Res. 2019 Jan 22. Epub 2019 Jan 22. PMID:
30671870
Article Published Date
: Jan 21, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Aluminum Toxicity
,
Alzheimer's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Neuroprotective Agents
Problem Substances
:
Aluminum Chloride
[+]
Asiatic acid is a potent nutraceutical agent against the progression of Parkinson's disease.
Mar 31, 2016
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Apr ;7(4):1999-2005. PMID:
26999333
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Parkinson's Disease
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Asiatic acid may be a potential therapeutic agent for glaucoma.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Neurosci. 2018 ;12:489. Epub 2018 Jul 20. PMID:
30079010
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Glaucoma
Pharmacological Actions
:
Anti-Apoptotic
[+]
Asiatic acid protects against cisplatin-induced acute kidney injury via anti-apoptosis and anti-inflammation.
Oct 31, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Nov ;107:1354-1362. Epub 2018 Aug 30. PMID:
30257350
Article Published Date
: Oct 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Chemotherapy-Induced Toxicity: Cisplatin
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Chemoprotective Agents
[+]
Aspalathin protects the heart against hyperglycemia-induced oxidative damage.
Jan 13, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2017 Jan 14 ;22(1). Epub 2017 Jan 14. PMID:
28098811
Article Published Date
: Jan 13, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Rooibos
Diseases
:
Hyperglycemia
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Nrf2 activation
[+]
Astaxanthin alleviated acute lung injury by inhibiting oxidative/nitrative stress and the inflammatory response in mice.
Sep 10, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Sep 11 ;95:974-982. Epub 2017 Sep 11. PMID:
28915539
Article Published Date
: Sep 10, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Lung Injury: Acute
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
NF-kappaB Inhibitor
[+]
Astaxanthin alleviates inflammatory response in neonatal necrotizing enterocolitis.
Dec 31, 2022
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Gastroenterol Res Pract. 2023 ;2023:6078308. Epub 2023 Mar 27. PMID:
37021078
Article Published Date
: Dec 31, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Inflammation
,
Necrotising enterocolitis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
NF-kappaB Inhibitor
[+]
Astaxanthin ameliorates damage to the cerebral cortex, hippocampus and cerebellar cortex caused by methotrexate.
Nov 30, 2021
Click here to read the entire abstract
Pubmed Data
: Biotech Histochem. 2021 Dec 1:1-12. Epub 2021 Dec 1. PMID:
34850645
Article Published Date
: Nov 30, 2021
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Drug Toxicity: Methotrexate
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
Problem Substances
:
Methotrexate
[+]
Astaxanthin ameliorates the redox imbalance in lymphocytes of experimental diabetic rats.
Aug 05, 2010
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2010 Aug 5;186(3):306-15. Epub 2010 May 31. PMID:
20513374
Article Published Date
: Aug 05, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Diabetes: Immune Problems
,
Diabetes: Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Antiproliferative
[+]
Astaxanthin attenuates alcoholic cardiomyopathy via inhibition of endoplasmic reticulum stress-mediated cardiac apoptosis.
Dec 18, 2020
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2020 Dec 19:115378. Epub 2020 Dec 19. PMID:
33352188
Article Published Date
: Dec 18, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Alcohol Toxicity
,
Cardiomyopathy
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
[+]
Astaxanthin attenuates cardiovascular dysfunction associated with deoxycorticosterone acetate-salt-induced hypertension.
Mar 23, 2022
Click here to read the entire abstract
Pubmed Data
: Clin Exp Hypertens. 2022 Mar 24:1-14. Epub 2022 Mar 24. PMID:
35322744
Article Published Date
: Mar 23, 2022
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Hypertension
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
[+]
Astaxanthin attenuates contrast agent-induced acute kidney injury in vitro and in vivo.
Jan 23, 2018
Click here to read the entire abstract
Pubmed Data
: Int Urol Nephrol. 2018 Jan 24. Epub 2018 Jan 24. PMID:
29368247
Article Published Date
: Jan 23, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Kidney Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Renoprotective
[+]
Astaxanthin attenuates hepatic damages and mitochondrial dysfunction in nonalcoholic fatty liver disease.
May 21, 2020
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2020 May 22. Epub 2020 May 22. PMID:
32446270
Article Published Date
: May 21, 2020
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Astaxanthin can inhibit the lipid peroxidation, reduce the apoptosis, reduce the spinal cord edema.
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2018 May 1 ;32(5):548-553. PMID:
29806341
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Apoptotic
,
Hypolipidemic
,
Neuroprotective Agents
[+]
Astaxanthin enhances the longevity of Saccharomyces cerevisiae by decreasing oxidative stress and apoptosis.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: FEMS Yeast Res. 2019 Jan 1 ;19(1). PMID:
30312390
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
[+]
Astaxanthin exerted a reobvious neuroprotective effect in pilocarpine-induced status epilepticus rats.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Cell Neurosci. 2019 ;13:123. Epub 2019 Mar 29. PMID:
30983975
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Epilepsy
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Neuroprotective Agents
