Anti-Apoptotic

Name	AC	CK
Flavonoids	164	275
Ginsenosides	133	244
Ginkgo biloba	69	141
Tanshinone IIA	61	118
Curcumin	75	113
Astragaloside	57	104
Astaxanthin	59	101
Berberine	49	87
Melatonin	52	87
Resveratrol	51	84
Puerarin	49	79
Hydrogen Water	35	72
Thymoquinone	39	67
Quercetin	36	64
Paeoniflorin	43	61
Vitamin C	29	61
EGCG (Epigallocatechin gallate)	35	54
Citrus naringin	30	50
Apigenin	25	49
Hesperidin	24	47
Naringenin	27	46
Luteolin	17	45
Lycopene	26	45
Safflower	30	45
Polyphenols	24	44
Gastrodin	24	42
Chrysin	23	39
Crocin	22	39
Alpha-Lipoic Acid	21	38
Grape Seed Extract	22	37
Genistein	19	35
Rutin	17	35
Selenium	20	35
Anthocyanins	21	34
Kaempferol	18	34
Sulforaphane	18	34
Goji	20	32
Nobiletin	19	32
Paeonol	19	32
Panax Notoginseng	19	32
Salvia miltiorrhiza	21	32
Emodin	19	31
Hydrogen: Molecular	15	31
Fisetin	15	30
Peony	19	29
Coenzyme Q10	16	28
Ferulic acid	16	27
Icariin	18	27
Allicin	15	25
Royal Jelly	9	25
Asiatic Acid	15	24
Myricetin	16	24
Reishi Mushroom	17	24
Catechin	11	23
Fucoidan	15	23
Ginger	12	23
Ligustrazine	13	23
Lotus	17	23
Mangiferin	15	23
Pterostilbene	15	23
Vitamin D	13	23
Baicalein	14	22
Carnosic Acid	11	22
Citicoline	8	22
Dogwood	16	22
Garlic	14	22
Honokiol	14	22
Moringa oleifera	12	22
Syringic Acid	14	22
Verbascoside	14	22
Caffeic acid phenethyl ester	12	21
Cannabidiol	14	21
Ellagic Acid	12	21
Leonurine	11	21
NAC (N-acetyl-L-cysteine)	10	21
Nicotinamide Mononucleotide	12	21
Nigella sativa (aka Black Seed)	12	21
Urolithin A	13	21
Pomegranate	10	20
Huperzine	11	19
Punicalagin	9	19
Andrographolide	10	18
Betulinic acid	10	18
Carvacrol	9	18
Chlorogenic Acid	11	18
Garcinia kola	9	18
Gingerol	10	18
Shikonin	10	18
Diosgenin	9	17
Ginseng (Korean)	7	17
Organosulfur Compounds	11	17
Rose	12	17
Blueberry	9	16
Poria cocos	10	16
Procyanidin B2	8	16
Sea buckthorn	5	16
Sesamol	8	16
Vitamin E	10	16
Celastrol	10	15
Formononetin	9	15
Probiotics	8	15
Turmeric	8	15
DHA (Docosahexaenoic Acid)	3	14
Geraniol	7	14
Ginseng	10	14
Licorice	8	14
Oleuropein	10	14
Vanillic Acid	7	14
Dates	7	13
Diosmin	7	13
Frankincense	9	13
Fucoxanthin	7	13
Lion's Mane (Hericium Erinaceus)	8	13
Olive leaf extract	7	13
Piceatannol	9	13
Walnut	8	13
Andrographis	6	12
Bergamot orange	2	12
Burdock	6	12
Cordyceps Militaris	7	12
Cordyceps sinensis	7	12
Crocetin	5	12
Eriodictyol	7	12
Hydroxytyrosol	7	12
Magnolol	8	12
Mulberry	8	12
Rosmarinic acid	6	12
Ursolic Acid	7	12
Vitexins	9	12
Arctigenin	6	11
Fenugreek	7	11
Fermented Foods and Beverages	6	11
Gallic Acid	4	11
Gotu Kola	7	11
Honeysuckle	8	11
Indole-3-Carbinol	7	11
Medicinal Mushrooms	6	11
Persimmon	7	11
Piperine	7	11
Tetrahydrocurcumin	7	11
Wogonin	7	11
Angelica	5	10
Apocynin	5	10
Apple	6	10
Ashwagandha	7	10
Bee Venom	6	10
Camel Milk	1	10
Carnitine	1	10
Carnosine	6	10
Dandelion	7	10
Echinacea	6	10
Horse Chestnut	6	10
Oleanolic acid	5	10
Rosemaric Acid	6	10
Saffron	6	10
Safranal	7	10
Sinomenine	7	10
Aloe Vera	5	9
Biochanin A	5	9
Capsaicin	6	9
Chaga Mushroom (Inonotus obliquus)	4	9
Chicoric Acid	4	9
Cyanidin 3-glucoside	6	9
Jujube	6	9
Neem	6	9
Sesamin	5	9
Apple Polyphenols	5	8
Astragalus	3	8
Bilberry	5	8
Bitter Melon	4	8
Curcuminoids	3	8
Diosmetin	4	8
Green Tea	5	8
Isoliquiritigenin	6	8
Lychee	4	8
Mangosteen	5	8
Nettle	4	8
P-Coumaric Acid	5	8
Parthenolide	6	8
Patchouli	6	8
Proanthocyanidins	5	8
Raspberry	5	8
Spirulina	4	8
Strawberry	4	8
6-Shogaol	5	7
Beet	4	7
Beta-Caryophyllene	4	7
Celery Oil	4	7
Delphinidin	3	7
Delta-tetrahydrocannabinol (THC)	3	7
Garlic: Aged	4	7
Isoflavones	5	7
Lactoferrin	5	7
Lupeol	4	7
Onion	4	7
Palmitoylethanolamide	4	7
Phlorotannins	5	7
Rooibos	4	7
Theanine	4	7
Thymol	4	7
Water: Deep Sea	4	7
Xanthones	4	7
Artesunate	3	6
Bacopa	6	6
Black Pepper	3	6
Cyanidin	4	6
Evening Primrose Oil	3	6
Kefir	4	6
Prickly Pear Cactus	3	6
Red Sage	3	6
Seaweed: Brown	5	6
Sweet Potato: Purple	3	6
Vanillin	4	6
Zinc	4	6
Basil	3	5
Bee Propolis	3	5
Cardamonin	4	5
Carotenoids	4	5
Cocoa	3	5
Cucurbitacin B	2	5
Eugenol	3	5
Folic Acid	5	5
Herb Bennet	3	5
Lemon Balm	3	5
Milk Thistle	3	5
Okra	3	5
Rosemary	3	5
Saikosaponin	3	5
Seaweed	4	5
Tangeretin	3	5
Vitamin E: alpha tocopherol	4	5
Vitamin K2	3	5
Wheat Bran	1	5
White Mulberry	3	5
acetyl-11-keto-beta-boswellic acid	3	5
Agaricus Blazei	2	4
Amla Fruit	3	4
Avocado	3	4
Babchi	2	4
Barberry	3	4
Bee Pollen	2	4
Bergamot	2	4
Black Currant	2	4
Calcium	2	4
Chamomile	2	4
Chrysanthemum Indicum	3	4
Cinnamaldehyde	3	4
Cinnamon	2	4
Diallyl sulfide	2	4
Guduchi	3	4
Gynostemma	3	4
Hawthorn	3	4
Lactobacillus paracasei	2	4
Lactobacillus rhamnosus	2	4
Mugwort	3	4
Olive	2	4
Omega-3 Fatty Acids	2	4
Oregano	2	4
Parsley	2	4
Phellinus Linteus	4	4
Phloretin	3	4
Piperlongumine	2	4
Propolis: Bee	2	4
Pycnogenol (Pine Bark)	2	4
Sesame Seeds	2	4
Silibinin	3	4
Tannic Acid	2	4
Taurine	3	4
Theaflavins	3	4
Thyme	2	4
Vinpocetine	2	4
Vitamin B-12	2	4
Xanthohumol	2	4
Zerumbone	3	4
Artichoke	2	3
Bamboo	2	3
Betaine	2	3
Bitter Orange	2	3
Black Tea	2	3
Butterbur	2	3
Corn Silk	3	3
Cryptoxanthin	2	3
Cucurbitacin E	2	3
Daidzein	2	3
Genipin	2	3
Glycyrrhizin	2	3
Hydrangea	2	3
Ketone Bodies	2	3
Kiwifruit	2	3
Kombucha Tea	2	3
Kudzu	2	3
Lactobacillus plantarum	2	3
Lactobacillus rhamnosus GG	2	3
Lentinan	2	3
Lignans	2	3
Lutein	2	3
Mango	2	3
Noni	2	3
Nordihydroguaiaretic acid (NDGA)	2	3
Oligosaccharides	2	3
Oridonin	2	3
Perillaldehyde	2	3
Rhubarb	2	3
Soursop	2	3
Stilbenes	3	3
Thistle	3	3
Toona sinensis	2	3
Acacia catechu	1	2
Achiote	1	2
Adlay	2	2
Agaricus brasiliensis	1	2
Amygdalin	1	2
Antrodia camphorata	2	2
Apple Cider Vinegar	1	2
Apples	1	2
Apricot	1	2
Arugula	1	2
Asparagus	1	2
Banaba	1	2
Banana	1	2
Barley	1	2
Benzyl isothiocyanate	1	2
Berbamine	1	2
Beta Sitosterol	1	2
Bifidobacterium Longum	1	2
Black Raspberry	1	2
Blackberry	1	2
Bloodroot	1	2
Blue Honeysuckle	1	2
Boron	1	2
Buckwheat	1	2
Cafestol	1	2
Carbon 60	1	2
Carnosol	1	2
Celery	1	2
Chlorella (Algae)	1	2
Chocolate	1	2
Citrus Peel	1	2
Citrus Triterpenoids	1	2
Clove	1	2
Coconut Oil	1	2
Coriandrum sativum	1	2
Coumestrol	1	2
Curry Tree	1	2
Cysteine (see N-Acetylcysteine)	1	2
DHEA (Dehydroepiandrosterone)	1	2
Dong Quai	1	2
Elm tree	2	2
Eucalyptus	1	2
False Black Pepper	1	2
Fig	1	2
Gardenia	1	2
Geranium	1	2
Geum japonicum	1	2
Ginseng (American)	1	2
Glycyrrhiza uralensis	2	2
Goldenthread	1	2
Graviola	1	2
Guarana	1	2
Guava	1	2
Hibiscus sabdariffa	1	2
Honey	1	2
Hops	1	2
Hu Zhang (Polygonum cuspidatum)	1	2
Huaier (Trametes robiniophila murr)	1	2
Isoquercitrin	2	2
Japanese cypress	1	2
Kimchi	1	2
Krill	1	2
L-arginine	1	2
Lactobacillus Acidophilus	1	2
Lactobacillus fermentum	1	2
Lactobacillus helveticus	1	2
Lactobacillus reuteri	1	2
Lauric acid	1	2
Lemon Verbena	1	2
Lettuce	1	2
Lignan	1	2
Lingonberry	2	2
Long Pepper	1	2
Loquat	1	2
Modified Rice Bran (MGN-3)	1	2
Mussel: Green-lipped (Perna canaliculus)	1	2
Myrrh	1	2
Myrtenol	1	2
Myrtle	1	2
Nattokinase	1	2
Niacin	1	2
Nicotinamide	1	2
Nicotinamide adenine dinucleotide (NADH)	1	2
Nutmeg	1	2
Oligonol	1	2
Orange	1	2
Oyster Mushroom	1	2
Panax Ginseng	1	2
Perilla	1	2
Pine Needle	1	2
Plantago	1	2
Plantago asiatica	1	2
Policosanol	2	2
Pomegranate Peel	1	2
Pomegranate Seed	1	2
Prunella vulgaris	2	2
Psychedelics:All	1	2
Psyllium	1	2
Raspberry ketone	1	2
Red Cabbage	1	2
Rice	1	2
Salvia divinorum	1	2
Saw Palmetto	1	2
Scopoletin	2	2
Shilajit	1	2
Shitake Mushroom	1	2
Silymarin	1	2
Spinach	1	2
St. Johns Wort	1	2
Star Fruit	1	2
Sumac	1	2
Sweet Potato	1	2
Syrian rue	1	2
Tauroursodeoxycholic acid	2	2
Tea Tree	1	2
Terminalia	1	2
Terminalia chebula	2	2
Testosterone	1	2
Turkey Tail Mushroom	1	2
Turmerones	1	2
Tyrosol	1	2
Ubiquinol	1	2
Verbena officinalis	1	2
Vinegar	1	2
Vitamin B-3 (Niacin)	1	2
Vitamin C: Intravenous	1	2
Water: Deuterium Depleted	1	2
Wheat Grass	1	2
Yellow Sweet Clover (Melilotus officinalis)	1	2
Yoghurt	1	2
neohesperidin	1	2
18β-Glycyrrhetinic Acid	1	1
Amygdalin (laetrile)	1	1
Anandamide	1	1
Avenanthramides	1	1
Ayurvedic formulation: Liv52	1	1
Bael	1	1
Bay Laurel	1	1
Beta-Elemene	1	1
Betanin	1	1
Betel	1	1
Bifidobacterium animalis	1	1
Bisdemethoxycurcumin	1	1
Black Tea Theaflavins	1	1
Caffeic Acid	1	1
Cannabinoids	1	1
Cannabis	1	1
Carrot	1	1
Celery seed	1	1
Chokeberry	1	1
Curcuma Comosa	1	1
Dihydrocurcumin	1	1
Elecampane	1	1
Endocannabinoids	1	1
Galactooligosaccharides	1	1
Garden Cress (Lepidium sativum)	1	1
Germanium	1	1
Glycitein	1	1
Grape	1	1
Grapefruit	1	1
Grapefruit peel extract	1	1
Harmine	1	1
Hibiscus	1	1
Holy Basil	1	1
Hyaluronic Acid	1	1
Ipriflavone	1	1
Lactobacillus probiotics	1	1
Laurus Nobilis. True Laurel	1	1
Lime	1	1
Liquiritigenin	1	1
Magnolia	1	1
Maple	1	1
Oat Bran	1	1
Oats	1	1
Oleocanthal	1	1
Orthosiphon	1	1
Papaya	1	1
Phyllanthus emblica	1	1
Purslane	1	1
Red Clover	1	1
Schisandra	1	1
Skullcap: Chinese	1	1
Sweet Orange	1	1
Tart Cherry	1	1
Taxifolin	1	1
Tomatidine	1	1
Velvet antler	1	1
Vitamin A	1	1
Yerba Mate	1	1
Zataria multiflora	1	1
beta-Carotene	1	1

[+]

Cardioprotective effects and possible mechanisms of luteolin for myocardial ischemia-reperfusion injury.Dec 31, 2021

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Cardiovasc Med. 2022 ;9:685998. Epub 2022 Apr 25. PMID: 35548432

Article Published Date : Dec 31, 2021

Study Type : Meta Analysis, Review

Additional Links

Substances : Luteolin

Diseases : Myocardial Ischemia

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Cardioprotective, Malondialdehyde Down-regulation

[+]

Ginkgolide B for myocardial ischemia/Reperfusion injury.Dec 31, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Front Pharmacol. 2023 ;14:1184774. Epub 2023 May 11. PMID: 37251340

Article Published Date : Dec 31, 2022

Study Type : Meta Analysis, Review

Additional Links

Substances : Ginsenosides

Diseases : Liver Damage

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Hepatoprotective

[+]

Astragaloside IV exerts renal protective effects in animals with diabetes mellitus through multiple signalling pathways.Sep 14, 2020

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Pubmed Data : Pharmacol Res. 2020 Sep 15 ;160:105192. Epub 2020 Sep 15. PMID: 32942018

Article Published Date : Sep 14, 2020

Study Type : Meta Analysis, Review

Additional Links

Substances : Astragaloside

Diseases : Diabetic Nephropathy

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Renoprotective

[+]

Available findings demonstrated the preclinical evidence that Ginsenoside-Rb1 has a potential neuroprotective effects.Dec 31, 2019

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Pubmed Data : Vestn Oftalmol. 2011 ;127(5):18-21. PMID: 22165093

Article Published Date : Dec 31, 2010

Study Type : Human Study

Additional Links

Substances : Citicoline

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

Cocoa procyanidins attenuate lipid peroxidation associated neuronal cell death in a manner relevant to Alzheimer's disease.May 15, 2009

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Pubmed Data : Free Radic Biol Med. 2009 May 15;46(10):1319-27. Epub 2009 Feb 25. PMID: 19248828

Article Published Date : May 15, 2009

Study Type : Human Study

Additional Links

Substances : Catechin

Diseases : Alzheimer's Disease, Neurodegenerative Diseases, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants

Additional Keywords : Proanthocyanidins

[+]

Docosahexaenoic acid counteracts the hypoxic-induced inflammatory and metabolic alterations.Oct 31, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2022 Nov 1 ;14(21). Epub 2022 Nov 1. PMID: 36364860

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Article Publish Status : This is a free article. Click here to read the complete article.

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Problem Substances : Arsenic Trioxide

[+]

Protective effects of delphinidin against H2O2-induced oxidative injuries in human retinal pigment epithelial cells.Aug 29, 2019

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biosci Rep. 2019 Aug 30 ;39(8). Epub 2019 Aug 15. PMID: 31345961

Article Published Date : Aug 29, 2019

Study Type : Human In Vitro

Additional Links

Substances : Delphinidin

Diseases : Hydrogen Peroxide Induced Toxicity, Macular Degeneration, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Nrf2 activation

[+]

Punicalagin protects human retinal pigment epithelium cells from ultraviolet radiation-induced oxidative damage.Jun 01, 2020

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Pubmed Data : Biol Trace Elem Res. 2014 Aug ;160(2):285-93. Epub 2014 Jun 27. PMID: 24965080

Article Published Date : Aug 01, 2014

Study Type : Human In Vitro

Additional Links

[+]

Anti-apoptotic and anti-inflammatory effects of an ethanolic extract of Lycium chinense root against particulate matter 10-induced cell death and inflammation.Sep 21, 2022

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Pubmed Data : Biomed Pharmacother. 2023 Sep 10 ;167:115471. Epub 2023 Sep 10. PMID: 37699317

Article Published Date : Sep 09, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Astaxanthin

Diseases : DNA damage, Oxidative Stress, Smoking

Pharmacological Actions : Anti-Apoptotic, Antioxidants

[+]

Astragaloside IV ameliorates peritoneal fibrosis.Jul 25, 2023

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Pubmed Data : IUBMB Life. 2022 May 5. Epub 2022 May 5. PMID: 35514074

Article Published Date : May 04, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Ferulic acid

Diseases : Acetaminophen (Tylenol) Toxicity , Liver Damage: Drug-Induced

Pharmacological Actions : Anti-Apoptotic, Hepatoprotective

Problem Substances : Acetaminophen, Paracetamol

[+]

Ferulic acid attenuates high glucose-induced apoptosis in retinal pigment epithelium cells.Dec 31, 2021

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Pubmed Data : J Nutr Biochem. 2022 Aug 3 ;109:109118. Epub 2022 Aug 3. PMID: 35933022

Article Published Date : Aug 02, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Genistein

Diseases : Alzheimer's Disease

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

Geraniol-mediated suppression of endoplasmic reticulum stress protects against cerebral ischemia-reperfusion injury.Dec 28, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2022 Dec 29 ;24(1). Epub 2022 Dec 29. PMID: 36613992

Article Published Date : Dec 28, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Geraniol

Diseases : Cerebral Ischemia

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

Ginger efficiently reduced the lung damage and protected the lungs from severe damage due to hyperoxia and inflammation. Aug 15, 2018

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Turk J Med Sci. 2018 Aug 16 ;48(4):892-900. Epub 2018 Aug 16. PMID: 30121057

Article Published Date : Aug 15, 2018

Study Type : Human: Case Report

Additional Links

Substances : Ginger

Diseases : Bronchopulmonary Dysplasia, Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Phytotherapy, Plant Extracts

[+]

Ginkgolide B exerts cardioprotective properties against doxorubicin-induced cardiotoxicity.Dec 31, 2015

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Pubmed Data : J Control Release. 2023 Jan ;353:216-228. Epub 2022 Nov 25. PMID: 36410615

Article Published Date : Dec 31, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Xanthones

Diseases : Cerebral Ischemia

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents

[+]

Protective mechanisms of 10-gingerol against myocardial ischemia.Jun 30, 2022

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : Biomater Sci. 2023 Oct 10 ;11(20):6862-6870. Epub 2023 Oct 10. PMID: 37646313

Article Published Date : Oct 09, 2023

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Coenzyme Q10, EGCG (Epigallocatechin gallate)

Diseases : Myocardial Infarction

Pharmacological Actions : Anti-Apoptotic, Cardioprotective

Additional Keywords : Natural Substance Synergy

[+]

Synergistic effects of ginkgolide B and protocatechuic acid on the treatment of Parkinson's disease. Aug 30, 2020

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Molecules. 2020 Aug 31 ;25(17). Epub 2020 Aug 31. PMID: 32878312

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Pubmed Data : J Food Sci. 2023 May ;88(5):2229-2245. Epub 2023 Apr 6. PMID: 37025094

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Pubmed Data : Synapse. 2020 Jul 8:e22181. Epub 2020 Jul 8. PMID: 32639628

Article Published Date : Jul 07, 2020

Study Type : Animal Study

Additional Links

Substances : Genistein

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Can J Physiol Pharmacol. 2016 Sep 2:1-9. Epub 2016 Sep 2. PMID: 27875075

Article Published Date : Sep 01, 2016

Study Type : Animal Study

Additional Links

Substances : Chamomile, Oregano

Diseases : Diabetic Complications

Pharmacological Actions : Alpha-amylase inhibitor, Anti-Apoptotic, Hypoglycemic Agents, Hypolipidemic

Additional Keywords : Natural Substance Synergy, Plant Extracts

Problem Substances : Alloxan

[+]

A ketogenic diet alleviates the apoptosis of granulosa cells.Nov 26, 2024

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Article Publish Status : This is a free article. Click here to read the complete article.

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Pubmed Data : J Ethnopharmacol. 2016 Nov 4 ;192:170-177. Epub 2016 Jul 9. PMID: 27401291

Article Published Date : Nov 03, 2016

Study Type : Animal Study

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Substances : Andrographis

Diseases : Cardiac Hypertrophy, High Fat Diet

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Cardioprotective, Cyclooxygenase 2 Inhibitors

Additional Keywords : Phytotherapy, Plant Extracts

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Acacetin alleviates myocardial ischaemia/reperfusion injury.Nov 30, 2022

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Administration of Nigella sativa can be used to prevent formaldehyde induced apoptosis and epithelial damage.Apr 30, 2017

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Pubmed Data : Niger J Clin Pract. 2017 May ;20(5):523-529. PMID: 28513508

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Pubmed Data : Biol Trace Elem Res. 2017 Nov ;180(1):153-163. Epub 2017 Mar 10. PMID: 28283953

Article Published Date : Oct 31, 2017

Study Type : Animal Study

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Substances : Agaricus Blazei

Diseases : Cadmium Poisoning

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants

Problem Substances : Cadmium

[+]

AGE has an ameliorative effect against CP-induced oxidative stress and renal damage through its antioxidant, anti-inflammatory and antiapoptotic properties. Dec 31, 2013

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Pubmed Data : Cancer Cell Int. 2014 ;14(1):92. Epub 2014 Sep 28. PMID: 25298749

Article Published Date : Dec 31, 2013

Study Type : Animal Study

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Substances : Garlic: Aged

Diseases : Chemotherapy-Induced Toxicity: Cisplatin, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Chemoprotective Agents, Renoprotective

Additional Keywords : Plant Extracts

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Pubmed Data : Andrologia. 2020 Jan 8:e13504. Epub 2020 Jan 8. PMID: 31912924

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Pubmed Data : Chin J Integr Med. 2017 Aug ;23(8):589-597. Epub 2016 Jul 13. PMID: 27412589

Article Published Date : Jul 31, 2017

Study Type : Animal Study

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Substances : Allicin

Diseases : Myocardial Infarction

Pharmacological Actions : Anti-Apoptotic, Cardioprotective

Additional Keywords : Allicin, Anti-Apoptotic, Cardioprotective, Myocardial Infarction

[+]

Allicin protects against renal ischemia-reperfusion injury by attenuating oxidative stress and apoptosis.Nov 24, 2021

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Pubmed Data : Food Funct. 2021 Jan 21 ;12(2):696-705. Epub 2021 Jan 7. PMID: 33410857

Article Published Date : Jan 20, 2021

Study Type : Animal Study

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Substances : Aloe Vera

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Alpha lipoic acid has a therapeutic role in ameliorating DOX-induced testicular damage.Mar 31, 2021

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Pubmed Data : Andrologia. 2021 Apr ;53(3):e13990. Epub 2021 Feb 2. PMID: 33529370

Article Published Date : Mar 31, 2021

Study Type : Animal Study

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Substances : Alpha-Lipoic Acid

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Chemoprotective Agents

[+]

Alpha lipoic acid possess protective effects against chlorpyrifos induced liver injury.Feb 22, 2018

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Ameliorative effect of N-acetylcysteine on the testicular tissue of adult male albino rats after glyphosate-based herbicide exposure.Feb 16, 2022

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Pubmed Data : J Biochem Mol Toxicol. 2022 Feb 17:e22997. Epub 2022 Feb 17. PMID: 35174928

Article Published Date : Feb 16, 2022

Study Type : Animal Study

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Substances : NAC (N-acetyl-L-cysteine)

Diseases : Glyphosate Toxicity, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Anti-Apoptotic, Antioxidants

Problem Substances : Glyphosate

[+]

Ameliorative effects of crocin on paraquat-induced oxidative stress in testis.Nov 30, 2019

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Pubmed Data : Toxicol Mech Methods. 2017 Jan 22:1-27. Epub 2017 Jan 22. PMID: 28110594

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Pubmed Data : PLoS One. 2022 ;17(10):e0276984. Epub 2022 Oct 27. PMID: 36301972

Article Published Date : Dec 31, 2021

Study Type : Animal Study

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Substances : Soursop

Diseases : Diabetic Complications

Pharmacological Actions : Alpha-glucosidase inhibitor , Anti-Apoptotic, Bcl-2 protein down-regulation, Hypoglycemic Agents

Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs

[+]

Antenatal pomegranate juice rescues hypoxia-induced fetal growth restriction in pregnant mice.May 31, 2018

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Pubmed Data : Placenta. 2018 Jun ;66:1-7. Epub 2018 Apr 16. PMID: 29884297

Article Published Date : May 31, 2018

Study Type : Animal Study

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Substances : Pomegranate

Diseases : Hypoxia, Pregnancy Complications

Pharmacological Actions : Anti-Apoptotic, Antioxidants

[+]

Anthocyanin from purple sweet potato attenuates lead-induced reproductive toxicity mediated by JNK signaling pathway in male mice.Aug 23, 2021

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Pubmed Data : Ecotoxicol Environ Saf. 2021 Aug 24 ;224:112683. Epub 2021 Aug 24. PMID: 34438266

Article Published Date : Aug 23, 2021

Study Type : Animal Study

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Substances : Anthocyanins, Sweet Potato: Purple

Diseases : Lead Poisoning, Male Reproductive Development Abnormalities

Pharmacological Actions : Anti-Apoptotic, Antioxidants

Problem Substances : Lead

[+]

Anthocyanin rich extract of red cabbage alleviates experimentally induced myocardial infarction.Dec 31, 2016

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Pubmed Data : Int J Mol Med. 2018 Mar ;41(3):1608-1618. Epub 2018 Jan 10. PMID: 29328429

Article Published Date : Feb 28, 2018

Study Type : Animal Study, In Vitro Study

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Substances : Anthocyanins, Grape Seed Extract

Diseases : Diabetes: Oxidative Stress, Diabetic Nephropathy

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Renoprotective

Additional Keywords : Proanthocyanidins

[+]

Anti-apoptosis and autophagy effects of melatonin protect rat chondrocytes.Jan 11, 2021

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Pubmed Data : Cartilage. 2021 12 ;13(2_suppl):1041S-1053S. Epub 2021 Nov 15. PMID: 34775836

Article Published Date : Jan 11, 2021

Study Type : Animal Study, In Vitro Study

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Substances : Melatonin

Diseases : Osteoarthritis

Pharmacological Actions : Anti-Apoptotic, Chondroprotective

[+]

Anti-diabetic effect mediated by Ramulus mori polysaccharides.Mar 05, 2015

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Pubmed Data : Carbohydr Polym. 2015 Mar 6 ;117:63-69. Epub 2014 Sep 28. PMID: 25498609

Article Published Date : Mar 05, 2015

Study Type : Animal Study

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Substances : Mulberry

Diseases : Hyperglycemia

Therapeutic Actions : Fasting/Caloric Restriction

Pharmacological Actions : Anti-Apoptotic, Hypoglycemic Agents, Pancreato Protective Agents

Additional Keywords : Polysaccharides

[+]

Anti-hypoglycemic and hepatocyte-protective effects of hyperoside against high-carbohydrate/high-fat diet and alloxan-induced diabetes.Dec 31, 2017

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Pubmed Data : Mol Biol Rep. 2020 Aug ;47(8):6053-6065. Epub 2020 Jul 31. PMID: 32737827

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Pubmed Data : Iran J Basic Med Sci. 2024 ;27(12):1515-1528. PMID: 39539451

Article Published Date : Dec 31, 2023

Study Type : Animal Study

Additional Links

Substances : Royal Jelly

Diseases : Microplastic Toxicity, Testicular Injury: Chemical/Metal Induced

Pharmacological Actions : Anti-Apoptotic, Antioxidants

Problem Substances : Nano Plastic-and Micro-Particles

[+]

Anti-oxidant effect of bergamot polyphenolic fraction counteracts doxorubicin-induced cardiomyopathy.May 31, 2018

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Pubmed Data : J Mol Cell Cardiol. 2018 Jun ;119:10-18. Epub 2018 Apr 12. PMID: 29654879

Article Published Date : May 31, 2018

Study Type : Animal Study

Additional Links

Substances : Bergamot

Diseases : Chemotherapy-Induced Toxicity: Doxorubicin

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Cardioprotective, Chemoprotective Agents

[+]

Antiamnesic and neuroprotective effects of an aqueous extract of Ziziphus jujuba.Dec 31, 2020

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Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:7973098. Epub 2019 Mar 20. PMID: 31015891

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Apigenin

Diseases : Myocardial Ischemia

Pharmacological Actions : Anti-Apoptotic, Cardioprotective

[+]

Apigenin-coated gold nanoparticles as a cardioprotective strategy against doxorubicin-induced cardiotoxicity.Feb 28, 2023

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Pubmed Data : Comp Biochem Physiol B Biochem Mol Biol. 2025 ;277:111068. Epub 2024 Dec 28. PMID: 39736455

Article Published Date : Dec 31, 2024

Study Type : Animal Study

Additional Links

Substances : Artichoke

Diseases : Fluoride Toxicity , Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Plant Extracts

Problem Substances : Sodium Fluoride

Adverse Pharmacological Actions : Apoptotic

[+]

Artificial tears containing epigallocatechin gallate and hyaluronic acid had a synergistic effect in the treatment of dry eye syndrome.Dec 31, 2015

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Pubmed Data : PLoS One. 2016;11(6):e0157982. Epub 2016 Jun 23. PMID: 27336157

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Pubmed Data : Mol Cell Biochem. 2016 Dec 21. Epub 2016 Dec 21. PMID: 28004351

Article Published Date : Dec 20, 2016

Study Type : Animal Study

Additional Links

Substances : Ashwagandha

Diseases : Brain Inflammation , Insomnia, Sleep Disorders

Pharmacological Actions : Anti-Anxiety Agents, Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

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View the Evidence: 3160 Abstracts with Anti-Apoptotic Research

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Cardioprotective effects and possible mechanisms of luteolin for myocardial ischemia-reperfusion injury.Dec 31, 2021

Ginkgolide B for myocardial ischemia/Reperfusion injury.Dec 31, 2018

Photobiomodulation in acute traumatic brain injury.Jan 31, 2023

The benefits of photobiomodulation in animal models of multiple sclerosis.Dec 31, 2023

The effect of ginsenosides on liver injury.Dec 31, 2022

Astragaloside IV exerts renal protective effects in animals with diabetes mellitus through multiple signalling pathways.Sep 14, 2020

Available findings demonstrated the preclinical evidence that Ginsenoside-Rb1 has a potential neuroprotective effects.Dec 31, 2019

Tanshinone IIA can effectively improve liver fibrosis and liver function.Dec 31, 2018

28‐days of polyphenol supplementation modulates the acute JNK, BAD, and Bcl‐2 response to heavy resistance exercise.Dec 31, 2017

7,8-dihydroxyflavone protects high glucose-damaged neuronal cells against oxidative stress.Dec 31, 2018

Berberine exhibits antioxidative effects and reduces apoptosis of the vaginal epithelium in bacterial vaginosis.Aug 31, 2019

Biological effects of rutin on skin aging.Jun 30, 2016

Camel milk had a regulatory effect on multiple parameters of inflammatory mediators, immunomodulators, antiapoptosis, and antioxidants.Oct 31, 2015

Citicoline has significant neuroprotective effect preventing apoptosis.Dec 31, 2010

Cocoa procyanidins attenuate lipid peroxidation associated neuronal cell death in a manner relevant to Alzheimer's disease.May 15, 2009

Docosahexaenoic acid counteracts the hypoxic-induced inflammatory and metabolic alterations.Oct 31, 2022

Effect of vitamin C administration on neutrophil apoptosis in septic patients after abdominal surgery.May 14, 2009

Efficacy of tanshinone IIA and mesenchymal stem cell treatment of learning and memory impairment in a rat model of vascular dementia.Dec 31, 2020

Electroacupuncture can enhance oocyte maturation and fertilization rate, and reduce the granulosa-cell apoptosis index in an IVF program.Sep 30, 2019

Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults.Jan 21, 2020

L-carnitine decreases myocardial injury in children undergoing open-heart surgery.May 31, 2024

Moderate-intensity exercise training ameliorates the diabetes-suppressed spermatogenesis and improves sperm parameters.Nov 30, 2019

Royal jelly consumption protects against radiation-induced apoptosis in human peripheral blood leukocytes.Dec 31, 2015

Sea buckthorn leaf extracts protect neuronal PC-12 cells from oxidative stress.Jul 27, 2017

Sudarshan Kriya practice may exert effects on immunity, aging, cell death, and stress regulation through transcriptional regulation.Jan 31, 2008

The in vivo transformation of bergamot juice phenolics in humans, may mitigate stearate-induced inflammation in myeloid angiogenic cells.Dec 05, 2017

The modulating effects of astaxanthin on apoptosis in women with polycystic ovarian syndrome.Dec 31, 2023

Vitamin C inhibits endothelial cell apoptosis in congestive heart failure.Oct 29, 2001

Panax ginseng alleviates benign prostatic hyperplasia while preventing finasteride-induced side effects.Dec 31, 2022

6-Gingerol attenuates ischemia-reperfusion-induced cell apoptosis in human AC16 cardiomyocytes.Dec 31, 2018

Angelica and Astragalus could protect against oxidative stress-induced apoptosis in kidney epithelium.Feb 16, 2016

Apigenin could be a potent dietary anti-oxidant regimen against edifenphos-induced toxicity on human health.Apr 30, 2019

Apigenin reduces proteasome inhibition-induced neuronal apoptosis.Oct 31, 2016

Berberine alleviates myocardial ischemia-reperfusion injury.Nov 30, 2022

Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction. Jul 31, 2021

Crocin improves lower extremity deep venous thrombosis.Sep 29, 2023

Cryptochrome 1 is modulated by blue light in human keratinocytes and exerts positive impact on human hair growth.Jan 31, 2021

EGCG protected against the effects of Dihydrotestosterone (DHT) by altering the miRNA expression profile in human dermal papilla cells.May 31, 2016

Fisetin inhibits PM2.5-induced apoptosis by inhibiting the ER stress response and production of ROS.Sep 17, 2021

Fucoxanthin reduced the inflammation response and maintained the integrity of the blood-retinal barrier.Nov 24, 2020

Hesperidin shielded human keratinocytes from UVB radiation-induced damage and apoptosis.Jan 14, 2016

Mangiferin could ameliorate methylmercury mediated mitochondrial dysfunction in human hepatic cells in vitro.Jan 31, 2017

Maternal exposure to bisphenol A induces fetal growth restriction via upregulating the expression of estrogen receptors.Sep 13, 2021

NAC with its protective effects may be a potential compound for prevention of malathion-induced brain injury.Mar 31, 2019

Pomegranate juice attenuated the damaging effects of cigarette smoke on cultured human alveolar cells.Dec 31, 2015

Procyanidin B2 alleviates palmitic acid-Induced injury in HepG2 cells.Dec 31, 2020

Protective effects of acteoside against X‑ray‑induced damage in human skin fibroblasts.Jul 31, 2015

Protective effects of crocetin on arsenic trioxide-induced oxidative stress.Oct 31, 2021

Protective effects of delphinidin against H2O2-induced oxidative injuries in human retinal pigment epithelial cells.Aug 29, 2019

Punicalagin protects human retinal pigment epithelium cells from ultraviolet radiation-induced oxidative damage.Jun 01, 2020

Resveratrol protects against oxidized low‑density lipoprotein‑induced human umbilical vein endothelial cell apoptosis.Mar 08, 2017

Resveratrol's neural protective effects for the injured embryoid body and cerebral organoid.Jul 11, 2022

Selenium prevents oxidative stress and apoptosis associated with mobile phone exposure.Aug 01, 2014

Self-assembled betulinic acid can be used to ameliorate the cytotoxic effects of Doxorubicin.Apr 30, 2015

Stress-induced miRNAs isolated from wheat have a unique therapeutic potential in ultraviolet-stressed human keratinocyte cells.Feb 28, 2022

Sulforaphane protects against ethanol-induced apoptosis in neural crest cells, a characteristic of Fetal Alcohol Syndrome, through restoration of Snail1 expression and epithelial-mesenchymal transition.Jul 08, 2019

THC exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.Sep 30, 2012

The anticancer/cytotoxic effect of a novel gallic acid derivative in non-small cell lung carcinoma A549 cells.Dec 31, 2023

The present study suggests that Vitamin D3 is a potentially useful agent for limiting influenza A virus-induced cellular injury via its pro-autophagic action.Mar 27, 2020

This demonstrates the broad neuroprotective action of apigenin against AD pathogenesis in a human disease model.Dec 31, 2015

Turmeric extract and its curcuminoids provided significant protection against photooxidative damage and apoptosis retinal cells.Feb 28, 2017

The protective role of sulforaphane and Homer1a in retinal ischemia-reperfusion injury.Sep 14, 2023

A new path in defining light parameters for hair growth: Discovery and modulation of photoreceptors in human hair follicle.Aug 31, 2017

Acacetin attenuates diabetes-induced cardiomyopathy.May 04, 2022

Albiflorin alleviation efficacy in osteoarthritis injury.Oct 04, 2023

Andrographolide alleviated blood-brain barrier disruption, neuronal apoptosis, and oxidative stress in subarachnoid hemorrhage.Mar 18, 2022

Andrographolide inhibits static mechanical pressure-induced intervertebral disc degeneration.Dec 31, 2022

Anti-apoptotic and anti-inflammatory effects of an ethanolic extract of Lycium chinense root against particulate matter 10-induced cell death and inflammation.Sep 21, 2022

Anti-inflammatory activity of carvacrol protects the heart from lipopolysaccharide-induced cardiac dysfunction.Jun 30, 2023

Arctium lappa L. root polysaccharides ameliorate CCl4-induced acute liver injury.Oct 21, 2023

Astaxanthin attenuated cigarette smoke extract-induced apoptosis via decreasing oxidative DNA damage in airway epithelium.Sep 09, 2023

Astragaloside IV ameliorates peritoneal fibrosis.Jul 25, 2023

Anti-Apoptotic

View the Evidence:
3160 Abstracts with Anti-Apoptotic Research