Anti-Fibrotic

Name	AC	CK
Flavonoids	46	99
Curcumin	36	82
Ginsenosides	36	82
Astragaloside	33	79
Tanshinone IIA	34	76
Salvia miltiorrhiza	28	49
Vitamin D	9	44
Lycopene	5	43
Puerarin	20	39
Resveratrol	20	39
Astaxanthin	16	38
Berberine	20	35
Pterostilbene	10	35
Quercetin	12	30
Vitamin E	6	30
EGCG (Epigallocatechin gallate)	15	23
Emodin	14	23
NAC (N-acetyl-L-cysteine)	10	23
Paeoniflorin	14	23
Asiatic Acid	11	21
Apigenin	8	20
Coenzyme Q10	6	19
Honokiol	9	19
Fucoidan	9	18
Melatonin	8	18
Citrus naringin	9	16
Naringenin	9	16
Fisetin	8	15
Ginkgo biloba	7	15
Piperine	4	15
Selenium	4	15
Curcumol	10	14
Diosgenin	7	14
Icariin	7	14
Mangiferin	8	14
Modified Citrus Pectin	3	14
Crocin	7	13
Reishi Mushroom	7	13
Turmeric	3	13
Baicalein	5	12
Fenugreek	5	12
Ginseng (Korean)	2	12
Lactoferrin	5	12
Myricetin	6	12
Paeonol	6	12
Pycnogenol (Pine Bark)	2	12
Silymarin	3	12
Ursolic Acid	6	12
Chlorogenic Acid	6	11
Licorice	5	11
Poria cocos	6	11
Safflower	6	11
Thymoquinone	6	11
Bee Propolis	1	10
Flaxseed	1	10
Gallic Acid	6	10
Holy Basil	1	10
Leonurine	6	10
Magnesium	1	10
Nigella sativa (aka Black Seed)	6	10
Sulforaphane	8	10
Sumac	1	10
Vitamin C	6	10
Zinc	1	10
Amygdalin	5	9
Arctigenin	6	9
Biochanin A	4	9
Ferulic acid	4	9
Fucoxanthin	5	9
Hydrogen Water	4	9
Nicotinamide Mononucleotide	5	9
Peony	6	9
Piceatannol	5	9
Tannic Acid	3	9
Astragalus	5	8
Betulinic acid	5	8
Celastrol	5	8
DHA (Docosahexaenoic Acid)	4	8
Honeysuckle	4	8
Lotus	5	8
Luteolin	4	8
Nobiletin	4	8
Phlorotannins	3	8
Sesamol	4	8
Shikonin	4	8
Beta-Elemene	5	7
Blueberry	4	7
Chrysin	4	7
Cinnamaldehyde	2	7
Diosmin	4	7
Genistein	4	7
Lignans	4	7
Piperlongumine	4	7
Vanillic Acid	3	7
Alpha-Lipoic Acid	3	6
Andrographolide	3	6
Fermented Foods and Beverages	3	6
Ginger	3	6
Gotu Kola	4	6
Kaempferol	4	6
Medicinal Mushrooms	3	6
Olive leaf extract	3	6
Palmitoylethanolamide	3	6
Panax Notoginseng	4	6
Pomegranate	4	6
Probiotics	3	6
Rose	4	6
Silibinin	3	6
Sinomenine	4	6
Verbascoside	3	6
Xanthones	3	6
Babchi	3	5
Bixin	3	5
Cannabidiol	3	5
Ginseng	3	5
Green Tea	3	5
Hesperidin	3	5
Hydroxytyrosol	2	5
Liquiritigenin	3	5
Neem	3	5
Polyphenols	3	5
Prunella vulgaris	1	5
Saikosaponin	5	5
Schisandra	1	5
Triphala	1	5
Wogonin	3	5
Allicin	2	4
Aloe Vera	2	4
Anthocyanins	2	4
Ashwagandha	2	4
Betanin	2	4
Caffeic acid phenethyl ester	2	4
Cannabinoids	3	4
Capsaicin	3	4
Carbon 60	2	4
Carvacrol	2	4
Celery Oil	2	4
Chokeberry	2	4
Cinnamon	2	4
Cyanidin 3-glucoside	2	4
Echinacea	2	4
Formononetin	2	4
Frankincense	2	4
Gastrodin	2	4
Geraniol	2	4
Grape Seed Extract	2	4
Isoliquiritigenin	3	4
Kefir	2	4
Krill	2	4
L-Carnitine	2	4
Lactobacillus rhamnosus GG	2	4
Lemon Balm	2	4
Magnolol	3	4
Mangosteen	2	4
Olive Oil	2	4
Omega-3 Fatty Acids	2	4
Orange	2	4
Oridonin	2	4
Phloretin	2	4
Red Sage	2	4
Rosmarinic acid	2	4
Spirulina	2	4
Tetrahydrocurcumin	2	4
White Mulberry	2	4
Yoghurt	2	4
Zerumbone	2	4
Amygdalin (laetrile)	2	3
Artesunate	2	3
Bee Venom	2	3
Bromelain	1	3
Burdock	2	3
Carnosic Acid	2	3
Chamomile	2	3
Cordyceps Militaris	2	3
Cordyceps sinensis	3	3
Dates	2	3
Evodiamine	2	3
Folate	1	3
Gingerol	2	3
Glycyrrhizin	2	3
Hawthorn	2	3
Hops	2	3
Indole-3-Carbinol	2	3
Milk Thistle	2	3
Moringa oleifera	2	3
Nicotinamide adenine dinucleotide (NADH)	2	3
Organosulfur Compounds	2	3
Parthenolide	2	3
Rhubarb	2	3
Rosemaric Acid	2	3
Vitamin B-12	1	3
2-Methoxyestradiol	1	2
Acai	1	2
Amla Fruit	1	2
Bacopa	1	2
Bamboo	1	2
Berries: All	1	2
Beta Sitosterol	1	2
Bifidobacterium Longum	1	2
Bisdemethoxycurcumin	1	2
Black Currant	1	2
Boron	1	2
Cafestol	1	2
Camel Milk	1	2
Cannabis	1	2
Carnosine	1	2
Chlorella (Algae)	1	2
Cinnamic acid	1	2
Cocoa	1	2
Corn Silk	1	2
Cranberry	1	2
Cucurbitacin B	1	2
Cucurbitacin E	1	2
Daidzein	1	2
Dandelion	1	2
Ellagic Acid	2	2
Epicatechin	1	2
Eucalyptus	1	2
Eugenol	1	2
Evening Primrose Oil	1	2
Garden Cress (Lepidium sativum)	1	2
Garlic: Aged	1	2
Glycyrrhiza uralensis	2	2
Guduchi	2	2
Gynostemma	2	2
Helenalin	1	2
Hibiscus sabdariffa	1	2
Honey	1	2
Hyperforin	1	2
Isothiocyanates	1	2
Kombucha Tea	1	2
Lactobacillus Acidophilus	1	2
Lemon	1	2
Ligustrazine	1	2
Lingonberry	1	2
Litchi	1	2
Loquat	1	2
Loquat Seeds	1	2
Lupeol	1	2
Manuka Honey	1	2
Mulberry	1	2
Myrtle	1	2
Nettle	1	2
Noni	1	2
Nutmeg	1	2
Oleanolic acid	1	2
Oleuropein	1	2
Oligonol	1	2
Olive	1	2
Onion	1	2
Perilla	1	2
Policosanol	1	2
Polyunsaturated Fatty Acids (PUFAs)	1	2
Pomegranate Seed	1	2
Prickly Pear Cactus	1	2
Propolis: Brazillian	1	2
Protandim	1	2
Radish	1	2
Raspberry	1	2
Raspberry ketone	1	2
Rice	1	2
Rice Bran	1	2
Rosemary	1	2
Royal Jelly	1	2
Rutin	1	2
Saffron	1	2
Sage	1	2
Salacia oblonga	1	2
Sea buckthorn	1	2
Spermidine	1	2
St. Johns Wort	1	2
Strawberry	1	2
Syringic Acid	1	2
Taurine	1	2
Thistle	1	2
Tocotrienols	1	2
Urolithin A	1	2
Vanillin	1	2
Vinpocetine	1	2
Vitamin E: Gamma-tocotrienol	1	2
Walnut	1	2
Watercress	1	2
Xanthohumol	1	2
Yellow Tea	1	2
Zataria multiflora	1	2
neohesperidin	1	2
Andrographis	1	1
Artichoke	1	1
Bitter Melon	1	1
Butyrate	1	1
Carnosol	1	1
Catechin	1	1
Celery seed	1	1
Chaga Mushroom (Inonotus obliquus)	1	1
Coffee	1	1
Curcuminoids	1	1
D-Limonene	1	1
Dong Quai	1	1
Harmine	1	1
Isoflavones	1	1
Ketone Bodies	1	1
Okra	1	1
Phellinus Linteus	1	1
Plantago	1	1
Plantago asiatica	1	1
Procyanidin B2	1	1
Scopoletin	1	1
Seaweed: Brown	1	1
Skullcap: Chinese	1	1
Stilbenes	1	1
Tangeretin	1	1
Vitamin A	1	1
Zhu Ling Mushroom	1	1
acetyl-11-keto-beta-boswellic acid	1	1

[+]

Ginsenoside can protect against the renal failure in diabetes.Oct 28, 2022

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Pubmed Data : J Ethnopharmacol. 2022 Oct 29 ;302(Pt A):115860. Epub 2022 Oct 29. PMID: 36341813

Article Published Date : Oct 28, 2022

Study Type : Meta Analysis, Review

Additional Links

Substances : Ginsenosides

Diseases : Diabetic Nephropathy

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

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Pubmed Data : Asian Pac J Cancer Prev. 2021 Dec 1 ;22(12):3941-3947. Epub 2021 Dec 1. PMID: 34967575

Article Published Date : Nov 30, 2021

Study Type : Human Study

Additional Links

Substances : Curcumin, Turmeric

Diseases : Oral Submucous Fibrosis

Pharmacological Actions : Anti-Fibrotic

Additional Keywords : Plant Extracts

[+]

Curcumin gel and Aloe Vera gel are effective in improving oral submucous fibrosis symptoms.Jan 31, 2021

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Pubmed Data : Contemp Clin Dent. 2019 Jul-Sep;10(3):531-541. PMID: 32308333

Article Published Date : Jun 30, 2019

Study Type : Human Study

Additional Links

Substances : Curcumin, Lycopene, Piperine

Diseases : Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.May 31, 2016

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Pubmed Data : Int J Food Sci Nutr. 2016 Jun ;67(4):461-9. Epub 2016 Mar 17. PMID: 26983396

Article Published Date : May 31, 2016

Study Type : Human Study

Additional Links

Substances : Flaxseed

Diseases : Insulin Resistance, Liver Fibrosis, Liver Steatosis, Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Integrative Medicine, Lifestyle Changes: Positive

Pharmacological Actions : Anti-Fibrotic, Enzyme Inhibitors, Hepatoprotective

Additional Keywords : Significant Treatment Outcome

[+]

Galectin-3 inhibition with modified citrus pectin in hypertension. Dec 31, 2020

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[+]

Diosgenin inhibits TGF-β1/Smad signaling and regulates epithelial mesenchymal transition in experimental pulmonary fibrosis.Apr 30, 2022

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Pubmed Data : Drug Chem Toxicol. 2022 May ;45(3):1264-1275. Epub 2020 Sep 14. PMID: 32924642

Article Published Date : Apr 30, 2022

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Diosgenin

Diseases : Chemotherapy-Induced Toxicity: Bleomycin

Pharmacological Actions : Anti-Fibrotic, Transforming growth factor beta (TGF-β) inhibitor

[+]

Effects of salvianolic acid A and salvianolic acid B in renal interstitial fibrosis.Oct 31, 2022

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Pubmed Data : Chin Med. 2023 Dec 10 ;18(1):161. Epub 2023 Dec 10. PMID: 38072948

Article Published Date : Dec 09, 2023

Study Type : Animal Study, In Vitro Study

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Substances : Salvia miltiorrhiza

Diseases : Cardiomyopathy, Myocardial Fibrosis

Pharmacological Actions : Anti-Fibrotic, Cardioprotective

[+]

Salvianolic acid B attenuates liver fibrosis by targeting Ecm1 and inhibiting hepatocyte ferroptosis.Jan 31, 2024

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Pubmed Data : Biofactors. 2017 Mar ;43(2):272-282. Epub 2016 Nov 1. PMID: 27801960

Article Published Date : Mar 01, 2017

Study Type : Animal Study

Additional Links

Substances : Melatonin

Diseases : Liver Cirrhosis

Pharmacological Actions : Anti-Fibrotic

Additional Keywords : Liver Regeneration

[+]

Acacetin improves endothelial dysfunction and aortic fibrosis in insulin-resistant SHR rats.Aug 31, 2020

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Pubmed Data : Clin Res Hepatol Gastroenterol. 2019 Dec 3. Epub 2019 Dec 3. PMID: 31810868

Article Published Date : Dec 02, 2019

Study Type : Animal Study

Additional Links

Substances : Vitamin D

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants

[+]

Administration of thymoquinone reduced renal fibrosis and permeability and improved oxidative stress status.Nov 30, 2017

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Amygdalin alleviates renal injury by suppressing inflammation, oxidative stress and fibrosis in streptozotocin-induced diabetes.Jan 14, 2021

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Pubmed Data : Int Immunopharmacol. 2021 Jan ;90:107151. Epub 2020 Dec 6. PMID: 33296784

Article Published Date : Dec 31, 2020

Study Type : Animal Study

Additional Links

Substances : Amygdalin

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Hepatoprotective, Interleukin-6 Downregulation, Transforming growth factor beta (TGF-β) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Analysis of the potential biological mechanisms of diosmin against renal fibrosis.May 12, 2023

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Pubmed Data : J Food Biochem. 2021 Jun 22:e13819. Epub 2021 Jun 22. PMID: 34159624

Article Published Date : Jun 21, 2021

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Pubmed Data : J Tradit Complement Med. 2019 Jan ;9(1):45-53. Epub 2018 Apr 27. PMID: 30671365

Article Published Date : Dec 31, 2018

Study Type : Animal Study, In Vitro Study

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Substances : Gallic Acid

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Antifibrotic mechanism of piceatannol in bleomycin-induced pulmonary fibrosis in mice.Dec 31, 2021

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Pubmed Data : J Nutr Biochem. 2016 Mar 2 ;43:27-35. Epub 2016 Mar 2. PMID: 28193580

Article Published Date : Mar 01, 2016

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Hepatic Steatosis, High Fat Diet, High Sugar Diet, Inflammation, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

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Pubmed Data : Front Pharmacol. 2017 ;8:513. Epub 2017 Aug 8. PMID: 28848434

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Diseases : Pulmonary Fibrosis: Bleomycin-Induced

Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents

[+]

Astragaloside IV improves renal function and fibrosis.Dec 31, 2017

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Pubmed Data : Front Pharmacol. 2022 ;13:965914. Epub 2022 Oct 20. PMID: 36339578

Article Published Date : Dec 31, 2021

Study Type : Animal Study

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Substances : Astragalus

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

[+]

Attenuating effects of dieckol on hypertensive nephropathy in spontaneously hypertensive rats.Apr 18, 2021

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Pubmed Data : Toxicology. 2023 Oct ;497-498:153638. Epub 2023 Sep 30. PMID: 37783230

Article Published Date : Sep 30, 2023

Study Type : Animal Study

Additional Links

Substances : Flavonoids

Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Pulmonary Fibrosis: Bleomycin-Induced

Pharmacological Actions : Anti-Apoptotic, Anti-Fibrotic

[+]

Baicalin ameliorates pancreatic fibrosis by inhibiting the activation of pancreatic stellate cells in mice with chronic pancreatitis.Dec 31, 2019

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Beneficial effects of berberine against pulmonary complications of experimental pulmonary arterial hypertension.Dec 31, 2022

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Pubmed Data : Life Sci. 2022 Nov 15 ;309:121040. Epub 2022 Oct 5. PMID: 36208663

Article Published Date : Nov 14, 2022

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents, Renoprotective

[+]

Beta-sitosterol can be used to attenuate pulmonary fibrosis through suppression of EMT by inhibiting the TGF-β1/Snail pathway.Sep 03, 2019

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Pubmed Data : J Agric Food Chem. 2019 Sep 4 ;67(35):9789-9795. Epub 2019 Aug 19. PMID: 31373816

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Pubmed Data : Toxicol Mech Methods. 2020 Jul 27:1-23. Epub 2020 Jul 27. PMID: 32718261

Article Published Date : Jul 26, 2020

Study Type : Animal Study

Additional Links

Substances : Curcumin, Pomegranate

Diseases : Chemically-Induced Liver Damage, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

[+]

Combined carvacrol and cilostazol ameliorate ethanol-induced liver fibrosis.Jan 26, 2023

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Pubmed Data : Int Immunopharmacol. 2023 Jan 27 ;116:109750. Epub 2023 Jan 27. PMID: 36709594

Article Published Date : Jan 26, 2023

Study Type : Animal Study

Additional Links

Substances : Carvacrol

Diseases : Alcoholic Liver Disease, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

[+]

CoQ10 may be a therapeutic candidate for antifibrotic methods.Dec 31, 2018

Curcumin improves cardiac fibrosis by inhibiting endothelial-mesenchymal transition through NRF2-DDAH-ADMA-NO pathway.Jan 31, 2022

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Pubmed Data : Zhongguo Zhong Yao Za Zhi. 2022 Feb ;47(3):745-752. PMID: 35178958

Article Published Date : Jan 31, 2022

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Myocardial Fibrosis

Pharmacological Actions : Anti-Fibrotic, Cardioprotective

[+]

Curcumin improves cardiac function and reduces cardiac fibrosis after myocardial infarction.Dec 31, 2020

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Pubmed Data : Kidney Int. 2004 Jul;66(1):112-20. PMID: 15200418

Article Published Date : Jul 01, 2004

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Kidney Diseases, Kidney Fibrosis

Pharmacological Actions : Anti-Fibrotic, Renoprotective

[+]

Curcumin modulated gut microbiota and alleviated renal fibrosis in 5/6 nephrectomy-induced chronic kidney disease.Dec 31, 2024

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Pubmed Data : J Food Biochem. 2022 Aug ;46(8):e14206. Epub 2022 Apr 26. PMID: 35474577

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Pubmed Data : Pharmacol Res Perspect. 2018 04 ;6(2):e00385. Epub 2018 Feb 19. PMID: 29468071

Article Published Date : Dec 31, 2017

Study Type : Animal Study

Additional Links

Substances : Curcumin, Tetrahydrocurcumin

Diseases : Cardiac Hypertrophy, Fibrosis

Pharmacological Actions : Anti-Fibrotic, Antioxidants, Cardioprotective

[+]

Diosgenin reduces acute kidney injury and ameliorates the progression to chronic kidney disease.Jul 28, 2024

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Pubmed Data : Biochem Cell Biol. 2017 06 ;95(3):400-414. Epub 2016 Nov 21. PMID: 28177765

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Diosmin

Diseases : Liver Cirrhosis, Radiation Induced Illness

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants

[+]

Pubmed Data : Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2021 Nov ;37(6):611-615. PMID: 34821093

Article Published Date : Oct 31, 2021

Study Type : Animal Study

Additional Links

Substances : Curcumol

Diseases : Liver Cirrhosis, Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

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Ginsenoside can protect against the renal failure in diabetes.Oct 28, 2022

Efficacy of lycopene in the treatment of oral submucous fibrosis.Jan 11, 2020

Evaluation of astragaloside IV in hepatic fibrosis: A meta-analysis. Apr 01, 2021

Protective role of baicalin in the dynamic progression of lung injury to idiopathic pulmonary fibrosis.May 31, 2023

Tanshinone IIA can effectively improve liver fibrosis and liver function.Dec 31, 2018

The effect of pterostilbene and its active ingredients on experimental pulmonary fibrosis in asthma.Sep 30, 2022

This study determines the positive efficacy of vitamin D supplementation for chronic liver disease.Apr 30, 2020

Vitamin E supplementation in the treatment on nonalcoholic fatty liver disease.Dec 31, 2022

Antifibrotic effects of Quercetin on TGF-β1-induced vocal fold fibroblasts.Dec 31, 2021

Apigenin could be an attractive therapeutic potential for the treatment of renal fibrosis.Mar 20, 2020

Association between dietary magnesium intake and liver fibrosis among type 2 diabetes mellitus patients.Jun 30, 2024

Association between serum vitamin D level and immune imbalance in advanced schistosomiasis patients with liver fibrosis.Feb 03, 2021

Astaxanthin may have a positive impact on mouth opening and burning sensation in individuals with oral submucous fibrosis.Jan 31, 2024

Black turmeric and Aloe vera in the management of oral submucous fibrosis.Nov 30, 2021

Curcumin gel and Aloe Vera gel are effective in improving oral submucous fibrosis symptoms.Jan 31, 2021

Effects of resveratrol supplementation on cardiac remodeling in hypertensive patients.Feb 27, 2023

Efficacy of topical tulsi paste for the management of oral submucous fibrosis.Mar 31, 2022

Evaluation of efficacy of curcumin along with lycopene and piperine in the management of oral submucous fibrosis.Jun 30, 2019

Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.May 31, 2016

Galectin-3 inhibition with modified citrus pectin in hypertension. Dec 31, 2020

Korean Red Ginseng could be used as a complementary therapy for chronic hepatitis B.Nov 30, 2016

NAC could ameliorate COPD-induced pulmonary fibrosis by promoting immune response.Jan 02, 2021

Protective effects of propolis on hepatic steatosis and fibrosis among patients with nonalcoholic fatty liver disease.Feb 28, 2021

Pycnogenol®-Centellicum® supplementation improves lung fibrosis and Post-Covid-19 lung healing.Jun 27, 2021

Silymarin may reduce liver fibrosis.Apr 14, 2017

The effects of sumac powder supplementation in patients with non-alcoholic fatty liver disease.Oct 31, 2020

There was less fibrosis in elderly subjects supplemented with selenium and coenzyme Q10.Dec 07, 2017

Treatment with lycopene led to improvement in the symptoms of oral submucous fibrosis in the present study.Jul 10, 2020

Zinc administration and improved serum markers of hepatic fibrosis in patients with autoimmune hepatitis.Jun 01, 2021

Activation of Sirtuin3 by honokiol ameliorates alveolar epithelial cell senescence in experimental silicosis.Jul 31, 2024

Melatonin ameliorates hepatic fibrosis via the melatonin receptor 2-mediated upregulation of BMAL1 and anti-oxidative enzymes.Mar 04, 2024

Astaxanthin may be useful as a preventive/therapeutic agent for cardiac dysfunction and myocardial fibrosis.Mar 11, 2017

Baicalein represses TGF-β1-induced fibroblast differentiation through the inhibition of miR-21.Jan 01, 2018

Chebulagic acid and Chebulinic acid inhibit TGF-β1 induced fibrotic changes in the chorio-retinal endothelial cells by inhibiting ERK phosphorylation.Jan 01, 2019

Cinnamaldehyde may be able to slow down the progression of cardiac fibrosis.Mar 20, 2017

High-fluence light-emitting diode-generated red light modulates the transforming growth factor-beta pathway in human skin fibroblasts.Sep 30, 2018

Lactoferrin attenuated urban particulate matter-induced nephrotoxicity.Dec 13, 2022

Methyl ferulic acid attenuates liver fibrosis and hepatic stellate cell activation through the TGF-β1/Smad and NOX4/ROS pathways.Feb 01, 2019

Phlorotannins should be considered a promising candidate for use in the prevention of vocal fold fibrosis.Jan 11, 2020

Photobiomodulation therapy enhances the anti-fibrotic activity of adipose-derived mesenchymal stem cells.Feb 01, 2019

Prunella vulgaris attenuates diabetic renal injury.Mar 29, 2017

Puerarin attenuates the endothelial-mesenchymal transition induced by oxidative stress in human coronary artery endothelial cells.Nov 04, 2020

Schisanhenol may be a potential anti-liver fibrosis drug.Mar 19, 2020

The antifibrotic effect of quercetin can be enhanced by adding methyl group on functionally important position.Dec 01, 2019

Trigonelline reverses high glucose-induced proliferation, fibrosis of mesangial cells via modulation of Wnt signaling pathway.Feb 08, 2022

A synergistic mechanism of Liquiritin and Licochalcone B from Glycyrrhiza uralensis against COPD.Apr 19, 2024

Acteoside delays the fibrosis process of diabetic nephropathy by anti-oxidation and regulating the autophagy-lysosome pathway.Jun 06, 2024

Alpha-mangostin alleviate renal interstitial fibrosis.Nov 30, 2023

An alleviative effect of Lonicerae japonicae flos water extract against liver fibrogenesis in vitro and in vivo.Apr 30, 2024

Andrographolide inhibits corneal fibroblast to myofibroblast differentiation in vitro.Jan 08, 2022

Asiatic acid alleviates liver fibrosis via multiple signaling pathways based on integrated network pharmacology and lipidomics.Aug 09, 2022

Astragaloside IV ameliorates peritoneal fibrosis.Jul 25, 2023

Astragaloside IV protects against lung injury and pulmonary fibrosis in COPD.Sep 07, 2023

Baicalein improves renal interstitial fibrosis by inhibiting the ferroptosis in vivo and in vitro.Apr 14, 2024

Biochanin A inhibits cardiac hypertrophy and fibrosis in vivo and in vitro.Dec 31, 2023

Bromelain mitigates liver fibrosis via targeting hepatic stellate cells.May 31, 2023

Combination treatment with hydroxytyrosol and vitamin E improves NAFLD-related fibrosis.Sep 13, 2022

Cryptotanshinone alleviates liver fibrosis via inhibiting STAT3/CPT1A-dependent fatty acid oxidation in hepatic stellate cells.Jun 24, 2024

Diosgenin alleviates arsenic trioxide induced cardiac fibrosis.Jul 24, 2024

Diosgenin inhibits TGF-β1/Smad signaling and regulates epithelial mesenchymal transition in experimental pulmonary fibrosis.Apr 30, 2022

Effects of salvianolic acid A and salvianolic acid B in renal interstitial fibrosis.Oct 31, 2022

Fucoxanthin exert dose-dependent antifibrotic and anti-inflammatory effects on CCl4-induced liver fibrosis.Aug 31, 2023

Ginkgolic acid improves bleomycin-induced pulmonary fibrosis.Dec 31, 2021

Ginsenoside Rb1 induces hepatic stellate cell ferroptosis to alleviate liver fibrosis.Apr 30, 2024

Icariin attenuates renal fibrosis in vivo and in vitro by inhibiting the Notch2/Hes-1 pathway.Apr 14, 2022

Inhalable cryptotanshinone spray-dried swellable microparticles for pulmonary fibrosis therapy.Feb 28, 2022

Integrative informatics analysis identifies that ginsenoside Re improves renal fibrosis through regulation of autophagy.Apr 28, 2024

Leonurine (SCM-198) attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4 .Dec 31, 2012

Low molecular weight fucoidan inhibits pulmonary fibrosis.Dec 31, 2021

Naringenin is a potential immunomodulator for inhibiting liver fibrosis.Feb 27, 2023

Phloretin mitigates oxidative injury, inflammation and fibrogenic responses.May 20, 2022

Repair effect of photobiomodulation combined with human umbilical cord mesenchymal stem cells on rats with acute lung injury.Aug 31, 2022

Anti-Fibrotic

View the Evidence:
1057 Abstracts with Anti-Fibrotic Research