Anti-Fibrotic

Name	AC	CK
Curcumin	24	46
Tanshinone IIA	15	44
Puerarin	15	31
Vitamin D	6	30
Astragaloside	15	24
Ginsenosides	14	23
Astaxanthin	10	21
Lycopene	3	21
Coenzyme Q10	5	17
Resveratrol	10	16
Flavonoids	8	14
Paeoniflorin	8	13
Piperine	3	13
Apigenin	3	12
Asiatic Acid	6	12
Berberine	7	12
Crocin	6	12
Ginseng (Korean)	2	12
Selenium	2	12
Emodin	7	11
Mangiferin	6	11
Thymoquinone	6	11
Flaxseed	1	10
Nigella sativa (aka Black Seed)	6	10
Quercetin	4	10
Silymarin	1	10
Naringenin	5	9
Pterostilbene	5	9
Fisetin	4	8
Fucoidan	4	8
Myricetin	4	8
Paeonol	4	8
EGCG (Epigallocatechin gallate)	5	7
Ferulic acid	3	7
Gallic Acid	4	7
Hydrogen Water	3	7
Safflower	4	7
Tannic Acid	2	7
Ursolic Acid	4	7
Betulinic acid	4	6
Curcumol	5	6
DHA (Docosahexaenoic Acid)	3	6
Honokiol	4	6
Licorice	3	6
Luteolin	3	6
NAC (N-acetyl-L-cysteine)	4	6
Salvia miltiorrhiza	4	6
Shikonin	3	6
Silibinin	3	6
Vitamin C	3	6
Baicalein	1	5
Beta-Elemene	3	5
Chrysin	3	5
Cinnamaldehyde	1	5
Gotu Kola	3	5
Kaempferol	3	5
Piperlongumine	3	5
Prunella vulgaris	1	5
Schisandra	1	5
Triphala	1	5
Arctigenin	3	4
Ashwagandha	2	4
Astragalus	2	4
Babchi	2	4
Blueberry	2	4
Cannabinoids	3	4
Celastrol	2	4
Chlorogenic Acid	2	4
Diosgenin	3	4
Diosmin	2	4
Fermented Foods and Beverages	2	4
Fucoxanthin	3	4
Grape Seed Extract	2	4
L-Carnitine	2	4
Lactobacillus rhamnosus GG	2	4
Medicinal Mushrooms	2	4
Melatonin	3	4
Modified Citrus Pectin	2	4
Oridonin	2	4
Palmitoylethanolamide	2	4
Pomegranate	3	4
Probiotics	2	4
Red Sage	2	4
Rosmarinic acid	2	4
Spirulina	2	4
Tetrahydrocurcumin	2	4
Vitamin E	2	4
Yoghurt	2	4
Artesunate	2	3
Bee Venom	2	3
Carnosic Acid	2	3
Chamomile	2	3
Citrus naringin	2	3
Evodiamine	2	3
Genistein	2	3
Indole-3-Carbinol	2	3
Isoliquiritigenin	2	3
Liquiritigenin	2	3
Milk Thistle	2	3
Peony	2	3
Rose	2	3
Rosemaric Acid	2	3
Sulforaphane	3	3
Wogonin	2	3
2-Methoxyestradiol	1	2
Allicin	1	2
Aloe Vera	1	2
Alpha-Lipoic Acid	1	2
Amygdalin	1	2
Bacopa	1	2
Bamboo	1	2
Berries: All	1	2
Beta Sitosterol	1	2
Betanin	1	2
Biochanin A	1	2
Bisdemethoxycurcumin	1	2
Caffeic acid phenethyl ester	1	2
Camel Milk	1	2
Cannabis	1	2
Carvacrol	1	2
Chlorella (Algae)	1	2
Cinnamon	1	2
Corn Silk	1	2
Cranberry	1	2
Cucurbitacin B	1	2
Cucurbitacin E	1	2
Dandelion	1	2
Fenugreek	1	2
Formononetin	1	2
Frankincense	1	2
Garlic: Aged	1	2
Geraniol	1	2
Ginger	1	2
Ginseng	1	2
Green Tea	1	2
Gynostemma	2	2
Helenalin	1	2
Hesperidin	1	2
Hibiscus sabdariffa	1	2
Honey	1	2
Hops	1	2
Isothiocyanates	1	2
Kefir	1	2
Kombucha Tea	1	2
Krill	1	2
Lactoferrin	1	2
Lemon	1	2
Lemon Balm	1	2
Ligustrazine	1	2
Loquat	1	2
Loquat Seeds	1	2
Lotus	1	2
Magnolol	1	2
Myrtle	1	2
Noni	1	2
Oleanolic acid	1	2
Oligonol	1	2
Omega-3 Fatty Acids	1	2
Orange	1	2
Panax Notoginseng	1	2
Parthenolide	1	2
Perilla	1	2
Piceatannol	1	2
Polyunsaturated Fatty Acids (PUFAs)	1	2
Pomegranate Seed	1	2
Prickly Pear Cactus	1	2
Protandim	1	2
Radish	1	2
Rhubarb	1	2
Rosemary	1	2
Rutin	1	2
Sage	1	2
Salacia oblonga	1	2
Sea buckthorn	1	2
Spermidine	1	2
Strawberry	1	2
Taurine	1	2
Turmeric	1	2
Vanillin	1	2
Vitamin E: Gamma-tocotrienol	1	2
Walnut	1	2
Xanthohumol	1	2
Zataria multiflora	1	2
neohesperidin	1	2
Amygdalin (laetrile)	1	1
Bitter Melon	1	1
Butyrate	1	1
Carnosol	1	1
Celery seed	1	1
Coffee	1	1
Cordyceps sinensis	1	1
D-Limonene	1	1
Dong Quai	1	1
Ellagic Acid	1	1
Gingerol	1	1
Mangosteen	1	1
Moringa oleifera	1	1
Nicotinamide adenine dinucleotide (NADH)	1	1
Okra	1	1
Phellinus Linteus	1	1
Procyanidin B2	1	1
Stilbenes	1	1
Zhu Ling Mushroom	1	1
acetyl-11-keto-beta-boswellic acid	1	1

[+]

Curcumin gel and Aloe Vera gel are effective in improving oral submucous fibrosis symptoms.Jan 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Contemp Clin Dent. 2019 Jul-Sep;10(3):531-541. PMID: 32308333

Article Published Date : Jun 30, 2019

Study Type : Human Study

Additional Links

Substances : Curcumin, Lycopene, Piperine

Diseases : Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.May 31, 2016

Click here to read the entire abstract

Pubmed Data : Int J Food Sci Nutr. 2016 Jun ;67(4):461-9. Epub 2016 Mar 17. PMID: 26983396

Article Published Date : May 31, 2016

Study Type : Human Study

Additional Links

Substances : Flaxseed

Diseases : Insulin Resistance, Liver Fibrosis, Liver Steatosis, Nonalcoholic fatty liver disease (NAFLD)

Therapeutic Actions : Integrative Medicine, Lifestyle Changes: Positive

Pharmacological Actions : Anti-Fibrotic, Enzyme Inhibitors, Hepatoprotective

Additional Keywords : Significant Treatment Outcome

[+]

Galectin-3 inhibition with modified citrus pectin in hypertension. Dec 31, 2020

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Treatment with lycopene led to improvement in the symptoms of oral submucous fibrosis in the present study.Jul 10, 2020

Click here to read the entire abstract

Pubmed Data : J Oral Pathol Med. 2020 Jul 11. Epub 2020 Jul 11. PMID: 32652683

Article Published Date : Jul 10, 2020

Study Type : Human Study

Additional Links

Substances : Lycopene

Diseases : Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Zinc administration and improved serum markers of hepatic fibrosis in patients with autoimmune hepatitis.Jun 01, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Abrogation of the lipid signaling pathway by the indole reveals novel molecular pathways that may account for the protective effect of melatonin in liver fibrogenesis.Mar 01, 2017

Click here to read the entire abstract

Pubmed Data : Biofactors. 2017 Mar ;43(2):272-282. Epub 2016 Nov 1. PMID: 27801960

Click here to read the entire abstract

Pubmed Data : Clin Res Hepatol Gastroenterol. 2019 Dec 3. Epub 2019 Dec 3. PMID: 31810868

Article Published Date : Dec 02, 2019

Study Type : Animal Study

Additional Links

Substances : Vitamin D

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants

[+]

Administration of thymoquinone reduced renal fibrosis and permeability and improved oxidative stress status.Nov 30, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Res Pharm Sci. 2017 Dec ;12(6):479-487. PMID: 29204176

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Life Sci. 2021 Jan 15 ;265:118835. Epub 2020 Nov 28. PMID: 33253723

Article Published Date : Jan 14, 2021

Study Type : Animal Study

Additional Links

Substances : Amygdalin

Diseases : Diabetic Nephropathy

Pharmacological Actions : Anti-Fibrotic, anti-inflammatory, Antioxidants, Renoprotective

[+]

Amygdalin improves microcirculatory disturbance and attenuates pancreatic fibrosis.Nov 08, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Food Biochem. 2021 Jun 22:e13819. Epub 2021 Jun 22. PMID: 34159624

Article Published Date : Jun 21, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Tradit Complement Med. 2019 Jan ;9(1):45-53. Epub 2018 Apr 27. PMID: 30671365

Article Published Date : Dec 31, 2018

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Gallic Acid

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Antifibrotic mechanism of piceatannol in bleomycin-induced pulmonary fibrosis in mice.Dec 31, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Nutr Biochem. 2016 Mar 2 ;43:27-35. Epub 2016 Mar 2. PMID: 28193580

Article Published Date : Mar 01, 2016

Study Type : Animal Study

Additional Links

Substances : Astaxanthin

Diseases : Hepatic Steatosis, High Fat Diet, High Sugar Diet, Inflammation, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2017 ;8:513. Epub 2017 Aug 8. PMID: 28848434

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Diseases : Pulmonary Fibrosis: Bleomycin-Induced

Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents

[+]

Astragaloside IV improves renal function and fibrosis.Dec 31, 2017

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : J Ethnopharmacol. 2021 Jun 19 ;279:114350. Epub 2021 Jun 19. PMID: 34157326

Article Published Date : Jun 18, 2021

Study Type : Animal Study

Additional Links

Substances : Astragaloside

Diseases : Liver Cancer

Pharmacological Actions : Anti-Fibrotic, Antioxidants, Chemopreventive, Heme oxygenase-1 up-regulation, Nrf2 activation

[+]

Astragaloside IV modulates TGF‐β1‐dependent epithelial‐mesenchymal transition in bleomycin‐induced pulmonary fibrosisAug 31, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Life Sci. 2022 Nov 15 ;309:121040. Epub 2022 Oct 5. PMID: 36208663

Article Published Date : Nov 14, 2022

Study Type : Animal Study

Additional Links

Substances : Berberine

Diseases : Chemotherapy-Induced Kidney Damage, Chemotherapy-Induced Toxicity: Cisplatin

Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents, Renoprotective

[+]

Beta-sitosterol can be used to attenuate pulmonary fibrosis through suppression of EMT by inhibiting the TGF-β1/Snail pathway.Sep 03, 2019

Click here to read the entire abstract

Pubmed Data : J Agric Food Chem. 2019 Sep 4 ;67(35):9789-9795. Epub 2019 Aug 19. PMID: 31373816

[+]

[+]

Celastrol is a novel selective agonist of cannabinoid receptor 2 with anti-inflammatory and anti-fibrotic activity in a mouse model of systemic sclerosis.Jan 31, 2020

Click here to read the entire abstract

Pubmed Data : Phytomedicine. 2020 Feb ;67:153160. Epub 2019 Dec 26. PMID: 31901889

Article Published Date : Jan 31, 2020

Study Type : Animal Study

Additional Links

Substances : Celastrol

Diseases : Fibrosis, Pulmonary Fibrosis: Bleomycin-Induced

Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents

[+]

Chamomile hydroalcoholic extract may be able to diminish the toxic effects of bleomycin on the lung tissues.Sep 30, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Int J Mol Sci. 2021 Sep 23 ;22(19). Epub 2021 Sep 23. PMID: 34638597

Article Published Date : Sep 22, 2021

Study Type : Animal Study

Additional Links

Substances : Chrysin

Diseases : Kidney Fibrosis

Pharmacological Actions : Anti-Fibrotic, Renoprotective

[+]

Chrysin inhibits advanced glycation end products-induced kidney fibrosis.Jul 08, 2018

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Nutrients. 2018 Jul 9 ;10(7). Epub 2018 Jul 9. PMID: 29987200

Article Published Date : Jul 08, 2018

Study Type : Animal Study

Additional Links

Substances : Chrysin

Diseases : Advanced Glycation End products (AGE)

Pharmacological Actions : Anti-Fibrotic, Renoprotective

[+]

Click here to read the entire abstract

Pubmed Data : Toxicol Mech Methods. 2020 Jul 27:1-23. Epub 2020 Jul 27. PMID: 32718261

Article Published Date : Jul 26, 2020

Study Type : Animal Study

Additional Links

Substances : Curcumin, Pomegranate

Diseases : Chemically-Induced Liver Damage, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

[+]

Combined carvacrol and cilostazol ameliorate ethanol-induced liver fibrosis.Jan 26, 2023

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2023 Jan 27 ;116:109750. Epub 2023 Jan 27. PMID: 36709594

Article Published Date : Jan 26, 2023

Study Type : Animal Study

Additional Links

Substances : Carvacrol

Diseases : Alcoholic Liver Disease, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

[+]

CoQ10 may be a therapeutic candidate for antifibrotic methods.Dec 31, 2018

Curcumin inhibits liver fibrosis. Jan 01, 2002

Click here to read the entire abstract

Pubmed Data : J Pharm Pharmacol. 2002 Jan;54(1):119-26. PMID: 11829122

Article Published Date : Jan 01, 2002

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Curcumin is a potent antifibrotic agent and a promising treatment for diabetic nephropathy.Dec 31, 2016

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Pubmed Data : Biochem Cell Biol. 2017 06 ;95(3):400-414. Epub 2016 Nov 21. PMID: 28177765

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Diosmin

Diseases : Liver Cirrhosis, Radiation Induced Illness

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants

[+]

Click here to read the entire abstract

Pubmed Data : Int Immunopharmacol. 2018 Sep 1 ;64:162-169. Epub 2018 Sep 1. PMID: 30179845

Article Published Date : Aug 31, 2018

Study Type : Animal Study

Additional Links

Substances : EGCG (Epigallocatechin gallate)

Diseases : Prostatic Hyperplasia: Benign

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

[+]

Click here to read the entire abstract

Pubmed Data : J Med Food. 2022 Aug ;25(8):836-844. Epub 2022 Aug 2. PMID: 35917528

Article Published Date : Jul 31, 2022

Study Type : Animal Study

Additional Links

Substances : Epicatechin

Diseases : Heart Failure, Myocardial Fibrosis

Pharmacological Actions : Anti-Fibrotic, Cardioprotective

[+]

Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.Nov 30, 2021

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

[+]

Fisetin alleviated bleomycin-induced pulmonary fibrosis.Dec 31, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2020 ;11:553690. Epub 2020 Dec 14. PMID: 33381023

Article Published Date : Dec 31, 2019

Study Type : Animal Study

Additional Links

Substances : Fisetin

Diseases : Pulmonary Fibrosis: Bleomycin-Induced

Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents

[+]

Fisetin alleviates atrial inflammation, remodelling, and vulnerability to atrial fibrillation after myocardial infarction.Nov 29, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Front Pharmacol. 2020 ;11:585163. Epub 2020 Nov 30. PMID: 33328989

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Exp Ther Med. 2022 Apr ;23(4):308. Epub 2022 Feb 24. PMID: 35340879

Article Published Date : Mar 31, 2022

Study Type : Animal Study

Additional Links

Substances : Reishi Mushroom

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Hepatoprotective

[+]

Ganoderic acid A inhibits bleomycin-induced lung fibrosis.Dec 31, 2019

Click here to read the entire abstract

Pubmed Data : Pharmacology. 2020 ;105(9-10):568-575. Epub 2020 Jan 15. PMID: 31940650

Geraniol prevents the atherogenic diet induced fibrosis in experimental hamsters.Sep 04, 2015

Click here to read the entire abstract

Pubmed Data : Eur J Pharmacol. 2015 Sep 5 ;762:102-11. Epub 2015 May 22. PMID: 26004525

Article Published Date : Sep 04, 2015

Study Type : Animal Study

Additional Links

Substances : Geraniol

Diseases : Atherosclerosis, Fibrosis, Oxidative Stress

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Ginger extract protects the heart against inflammation and fibrosis in diabetes.Sep 01, 2020

Click here to read the entire abstract

Pubmed Data : Can J Diabetes. 2020 Sep 2. Epub 2020 Sep 2. PMID: 33162372

Click here to read the entire abstract

Pubmed Data : Toxicol Lett. 2017 Mar 12 ;273:1-9. Epub 2017 Mar 12. PMID: 28300665

Article Published Date : Mar 11, 2017

Study Type : Animal Study

Additional Links

Substances : Grape Seed Extract

Diseases : Pulmonary Fibrosis: Bleomycin-Induced

Pharmacological Actions : Anti-Fibrotic, Chemoprotective Agents, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Click here to read the entire abstract

Pubmed Data : Food Funct. 2021 Oct 22. Epub 2021 Oct 22. PMID: 34676843

Article Published Date : Oct 21, 2021

Study Type : Animal Study

Additional Links

Substances : Piceatannol

Diseases : Chemically-Induced Liver Damage, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

[+]

Hepatoprotective effect of ultrasonicated ginseng berry extract on a rat mild bile duct ligation model.Sep 30, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Ginseng Res. 2019 Oct ;43(4):606-617. Epub 2018 Aug 10. PMID: 31695567

Article Published Date : Sep 30, 2019

Study Type : Animal Study

Additional Links

Substances : Ginseng, Ginsenosides

Diseases : Liver Failure: Acute, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

Additional Keywords : Plant Extracts

[+]

High-fat diet-induced metabolic syndrome and oxidative stress in obese rats are ameliorated by yogurt supplementation.Dec 26, 2019

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Click here to read the entire abstract

Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : J Agric Food Chem. 2022 Aug 17 ;70(32):9865-9876. Epub 2022 Aug 2. PMID: 35916281

Article Published Date : Aug 16, 2022

Study Type : Animal Study

Additional Links

Substances : Krill

Diseases : Diabetic Nephropathy

Pharmacological Actions : Anti-Fibrotic, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor

Anti-Fibrotic jQuery(function ($) { $(".node-field-image").click(function () { $(".node-field-image").toggleClass("open"); }); $(".node.topic>.colfull").click(function () { $(".node.topic>.colfull").toggleClass("open"); }); })

Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 751 Abstracts with Anti-Fibrotic Research

Limited to Members Only

Currently Available Sorting Options

Ginsenoside can protect against the renal failure in diabetes.Oct 28, 2022

Efficacy of lycopene in the treatment of oral submucous fibrosis.Jan 11, 2020

Evaluation of astragaloside IV in hepatic fibrosis: A meta-analysis. Apr 01, 2021

Tanshinone IIA can effectively improve liver fibrosis and liver function.Dec 31, 2018

The effect of pterostilbene and its active ingredients on experimental pulmonary fibrosis in asthma.Sep 30, 2022

This study determines the positive efficacy of vitamin D supplementation for chronic liver disease.Apr 30, 2020

Antifibrotic effects of Quercetin on TGF-β1-induced vocal fold fibroblasts.Dec 31, 2021

Apigenin could be an attractive therapeutic potential for the treatment of renal fibrosis.Mar 20, 2020

Association between serum vitamin D level and immune imbalance in advanced schistosomiasis patients with liver fibrosis.Feb 03, 2021

Black turmeric and Aloe vera in the management of oral submucous fibrosis.Nov 30, 2021

Curcumin gel and Aloe Vera gel are effective in improving oral submucous fibrosis symptoms.Jan 31, 2021

Effects of resveratrol supplementation on cardiac remodeling in hypertensive patients.Feb 27, 2023

Efficacy of topical tulsi paste for the management of oral submucous fibrosis.Mar 31, 2022

Evaluation of efficacy of curcumin along with lycopene and piperine in the management of oral submucous fibrosis.Jun 30, 2019

Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.May 31, 2016

Galectin-3 inhibition with modified citrus pectin in hypertension. Dec 31, 2020

Korean Red Ginseng could be used as a complementary therapy for chronic hepatitis B.Nov 30, 2016

NAC could ameliorate COPD-induced pulmonary fibrosis by promoting immune response.Jan 02, 2021

Protective effects of propolis on hepatic steatosis and fibrosis among patients with nonalcoholic fatty liver disease.Feb 28, 2021

Pycnogenol®-Centellicum® supplementation improves lung fibrosis and Post-Covid-19 lung healing.Jun 27, 2021

Silymarin may reduce liver fibrosis.Apr 14, 2017

The effects of sumac powder supplementation in patients with non-alcoholic fatty liver disease.Oct 31, 2020

There was less fibrosis in elderly subjects supplemented with selenium and coenzyme Q10.Dec 07, 2017

Treatment with lycopene led to improvement in the symptoms of oral submucous fibrosis in the present study.Jul 10, 2020

Zinc administration and improved serum markers of hepatic fibrosis in patients with autoimmune hepatitis.Jun 01, 2021

Astaxanthin may be useful as a preventive/therapeutic agent for cardiac dysfunction and myocardial fibrosis.Mar 11, 2017

Baicalein represses TGF-β1-induced fibroblast differentiation through the inhibition of miR-21.Jan 01, 2018

Chebulagic acid and Chebulinic acid inhibit TGF-β1 induced fibrotic changes in the chorio-retinal endothelial cells by inhibiting ERK phosphorylation.Jan 01, 2019

Cinnamaldehyde may be able to slow down the progression of cardiac fibrosis.Mar 20, 2017

Lactoferrin attenuated urban particulate matter-induced nephrotoxicity.Dec 13, 2022

Methyl ferulic acid attenuates liver fibrosis and hepatic stellate cell activation through the TGF-β1/Smad and NOX4/ROS pathways.Feb 01, 2019

Phlorotannins should be considered a promising candidate for use in the prevention of vocal fold fibrosis.Jan 11, 2020

Photobiomodulation therapy enhances the anti-fibrotic activity of adipose-derived mesenchymal stem cells.Feb 01, 2019

Prunella vulgaris attenuates diabetic renal injury.Mar 29, 2017

Puerarin attenuates the endothelial-mesenchymal transition induced by oxidative stress in human coronary artery endothelial cells.Nov 04, 2020

Schisanhenol may be a potential anti-liver fibrosis drug.Mar 19, 2020

The antifibrotic effect of quercetin can be enhanced by adding methyl group on functionally important position.Dec 01, 2019

Andrographolide inhibits corneal fibroblast to myofibroblast differentiation in vitro.Jan 08, 2022

Asiatic acid alleviates liver fibrosis via multiple signaling pathways based on integrated network pharmacology and lipidomics.Aug 09, 2022

Combination treatment with hydroxytyrosol and vitamin E improves NAFLD-related fibrosis.Sep 13, 2022

Diosgenin inhibits TGF-β1/Smad signaling and regulates epithelial mesenchymal transition in experimental pulmonary fibrosis.Apr 30, 2022

Effects of salvianolic acid A and salvianolic acid B in renal interstitial fibrosis.Oct 31, 2022

Icariin attenuates renal fibrosis in vivo and in vitro by inhibiting the Notch2/Hes-1 pathway.Apr 14, 2022

Low molecular weight fucoidan inhibits pulmonary fibrosis.Dec 31, 2021

Naringenin is a potential immunomodulator for inhibiting liver fibrosis.Feb 27, 2023

Phloretin mitigates oxidative injury, inflammation and fibrogenic responses.May 20, 2022

Successful treatment with hydrogen rich water in a case of chronic graft-versus-host-disease.Jun 30, 2016

Tanshinone IIA improves diabetes-induced renal fibrosis.Oct 31, 2022

Tanshinone IIA regulates Keap1/Nrf2 signal pathway by activating sestrin2 to restrain pulmonary fibrosis.Oct 28, 2022

Tanshinone IIA regulates the TGF-β1/Smad signaling pathway to ameliorate non-alcoholic steatohepatitis-related fibrosis.Jun 30, 2022

Ursolic acid alleviates Kupffer cells pyroptosis in liver fibrosis.Nov 30, 2022

Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation.Jul 08, 2022

Emodin promotes fibroblast apoptosis and prevents epidural fibrosis through PERK pathway in rats.Oct 09, 2019

Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.Jun 10, 2020

Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation.Nov 29, 2020

6-Gingerol, a functional polyphenol of ginger, reduces pulmonary fibrosis by activating Sirtuin1.Dec 31, 2021

A multi-herbal product called Protandim prevents fibrosis and capillary loss and preserves right ventricular function in rats.Nov 17, 2009

A potential anti-liver fibrosis mechanism of curcumol may be associated with the inhibition of NLRP3 inflammasomes.Jul 27, 2021

A. vera supplementation protects against development of cardiac inflammation, fibrosis, and oxidative stress in isoprenaline-administered rats.Aug 31, 2019

Abrogation of the lipid signaling pathway by the indole reveals novel molecular pathways that may account for the protective effect of melatonin in liver fibrogenesis.Mar 01, 2017

Activation of SIRT1 by resveratrol alleviates pressure overload-induced cardiac hypertrophy.Sep 07, 2021

Active components from Sea Buckthorn regulate hepatic stellate cell activation and liver fibrogenesis.Nov 20, 2018

Active vitamin D impedes the progression of non-alcoholic fatty liver disease.Dec 02, 2019

Administration of thymoquinone reduced renal fibrosis and permeability and improved oxidative stress status.Nov 30, 2017

Allicin could be used as a novel supplementary cardioprotective therapy to avoid trastuzumab-induced cardiotoxicity.May 20, 2022

Allicin has the potential to help in the treatment of diabetic nephropathy.Nov 14, 2020

Allyl isothiocyanate reduces liver fibrosis by regulating Kupffer cell activation.Jun 05, 2018

Aloin alleviates pathological cardiac hypertrophy via modulation of the oxidative and fibrotic response.Dec 31, 2021

Ameliorating effects of white mulberry on iron-overload-induced oxidative stress and liver fibrosis.Aug 27, 2021

Amelioration of bleomycin induced pulmonary fibrosis by administration of Salvianolic acid B.Nov 17, 2022

Ameliorative effects of arctigenin on pulmonary fibrosis induced by bleomycin via the antioxidant activity.Dec 31, 2021

Amygdalin alleviates renal injury by suppressing inflammation, oxidative stress and fibrosis in streptozotocin-induced diabetes.Jan 14, 2021

Anti-Fibrotic

View the Evidence:
751 Abstracts with Anti-Fibrotic Research