Anti-Fibrotic

Name	AC	CK
Curcumin	24	46
Tanshinone IIA	15	44
Puerarin	15	31
Vitamin D	6	30
Astragaloside	15	24
Ginsenosides	14	23
Astaxanthin	10	21
Lycopene	3	21
Coenzyme Q10	5	17
Resveratrol	10	16
Flavonoids	8	14
Paeoniflorin	8	13
Piperine	3	13
Apigenin	3	12
Asiatic Acid	6	12
Berberine	7	12
Crocin	6	12
Ginseng (Korean)	2	12
Selenium	2	12
Emodin	7	11
Mangiferin	6	11
Thymoquinone	6	11
Flaxseed	1	10
Nigella sativa (aka Black Seed)	6	10
Quercetin	4	10
Silymarin	1	10
Naringenin	5	9
Pterostilbene	5	9
Fisetin	4	8
Fucoidan	4	8
Myricetin	4	8
Paeonol	4	8
EGCG (Epigallocatechin gallate)	5	7
Ferulic acid	3	7
Gallic Acid	4	7
Hydrogen Water	3	7
Safflower	4	7
Tannic Acid	2	7
Ursolic Acid	4	7
Betulinic acid	4	6
Curcumol	5	6
DHA (Docosahexaenoic Acid)	3	6
Honokiol	4	6
Licorice	3	6
Luteolin	3	6
NAC (N-acetyl-L-cysteine)	4	6
Salvia miltiorrhiza	4	6
Shikonin	3	6
Silibinin	3	6
Vitamin C	3	6
Baicalein	1	5
Beta-Elemene	3	5
Chrysin	3	5
Cinnamaldehyde	1	5
Gotu Kola	3	5
Kaempferol	3	5
Piperlongumine	3	5
Prunella vulgaris	1	5
Schisandra	1	5
Triphala	1	5
Arctigenin	3	4
Ashwagandha	2	4
Astragalus	2	4
Babchi	2	4
Blueberry	2	4
Cannabinoids	3	4
Celastrol	2	4
Chlorogenic Acid	2	4
Diosgenin	3	4
Diosmin	2	4
Fermented Foods and Beverages	2	4
Fucoxanthin	3	4
Grape Seed Extract	2	4
L-Carnitine	2	4
Lactobacillus rhamnosus GG	2	4
Medicinal Mushrooms	2	4
Melatonin	3	4
Modified Citrus Pectin	2	4
Oridonin	2	4
Palmitoylethanolamide	2	4
Pomegranate	3	4
Probiotics	2	4
Red Sage	2	4
Rosmarinic acid	2	4
Spirulina	2	4
Tetrahydrocurcumin	2	4
Vitamin E	2	4
Yoghurt	2	4
Artesunate	2	3
Bee Venom	2	3
Carnosic Acid	2	3
Chamomile	2	3
Citrus naringin	2	3
Evodiamine	2	3
Genistein	2	3
Indole-3-Carbinol	2	3
Isoliquiritigenin	2	3
Liquiritigenin	2	3
Milk Thistle	2	3
Peony	2	3
Rose	2	3
Rosemaric Acid	2	3
Sulforaphane	3	3
Wogonin	2	3
2-Methoxyestradiol	1	2
Allicin	1	2
Aloe Vera	1	2
Alpha-Lipoic Acid	1	2
Amygdalin	1	2
Bacopa	1	2
Bamboo	1	2
Berries: All	1	2
Beta Sitosterol	1	2
Betanin	1	2
Biochanin A	1	2
Bisdemethoxycurcumin	1	2
Caffeic acid phenethyl ester	1	2
Camel Milk	1	2
Cannabis	1	2
Carvacrol	1	2
Chlorella (Algae)	1	2
Cinnamon	1	2
Corn Silk	1	2
Cranberry	1	2
Cucurbitacin B	1	2
Cucurbitacin E	1	2
Dandelion	1	2
Fenugreek	1	2
Formononetin	1	2
Frankincense	1	2
Garlic: Aged	1	2
Geraniol	1	2
Ginger	1	2
Ginseng	1	2
Green Tea	1	2
Gynostemma	2	2
Helenalin	1	2
Hesperidin	1	2
Hibiscus sabdariffa	1	2
Honey	1	2
Hops	1	2
Isothiocyanates	1	2
Kefir	1	2
Kombucha Tea	1	2
Krill	1	2
Lactoferrin	1	2
Lemon	1	2
Lemon Balm	1	2
Ligustrazine	1	2
Loquat	1	2
Loquat Seeds	1	2
Lotus	1	2
Magnolol	1	2
Myrtle	1	2
Noni	1	2
Oleanolic acid	1	2
Oligonol	1	2
Omega-3 Fatty Acids	1	2
Orange	1	2
Panax Notoginseng	1	2
Parthenolide	1	2
Perilla	1	2
Piceatannol	1	2
Polyunsaturated Fatty Acids (PUFAs)	1	2
Pomegranate Seed	1	2
Prickly Pear Cactus	1	2
Protandim	1	2
Radish	1	2
Rhubarb	1	2
Rosemary	1	2
Rutin	1	2
Sage	1	2
Salacia oblonga	1	2
Sea buckthorn	1	2
Spermidine	1	2
Strawberry	1	2
Taurine	1	2
Turmeric	1	2
Vanillin	1	2
Vitamin E: Gamma-tocotrienol	1	2
Walnut	1	2
Xanthohumol	1	2
Zataria multiflora	1	2
neohesperidin	1	2
Amygdalin (laetrile)	1	1
Bitter Melon	1	1
Butyrate	1	1
Carnosol	1	1
Celery seed	1	1
Coffee	1	1
Cordyceps sinensis	1	1
D-Limonene	1	1
Dong Quai	1	1
Ellagic Acid	1	1
Gingerol	1	1
Mangosteen	1	1
Moringa oleifera	1	1
Nicotinamide adenine dinucleotide (NADH)	1	1
Okra	1	1
Phellinus Linteus	1	1
Procyanidin B2	1	1
Stilbenes	1	1
Zhu Ling Mushroom	1	1
acetyl-11-keto-beta-boswellic acid	1	1

[+]

Galectin-3 inhibition with modified citrus pectin in hypertension. Dec 31, 2020

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Treatment with lycopene led to improvement in the symptoms of oral submucous fibrosis in the present study.Jul 10, 2020

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Pubmed Data : J Oral Pathol Med. 2020 Jul 11. Epub 2020 Jul 11. PMID: 32652683

Article Published Date : Jul 10, 2020

Study Type : Human Study

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Substances : Lycopene

Diseases : Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Zinc administration and improved serum markers of hepatic fibrosis in patients with autoimmune hepatitis.Jun 01, 2021

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Pubmed Data : Zhonghua Yi Xue Za Zhi. 2017 Mar 21 ;97(11):869-873. PMID: 28355745

Article Published Date : Mar 20, 2017

Study Type : Human In Vitro

Additional Links

Substances : Cinnamaldehyde

Diseases : Myocardial Fibrosis

Pharmacological Actions : Anti-Fibrotic

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Methyl ferulic acid attenuates liver fibrosis and hepatic stellate cell activation through the TGF-β1/Smad and NOX4/ROS pathways.Feb 01, 2019

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Pubmed Data : Chem Biol Interact. 2019 Feb 1 ;299:131-139. Epub 2018 Dec 11. PMID: 30543783

Abrogation of the lipid signaling pathway by the indole reveals novel molecular pathways that may account for the protective effect of melatonin in liver fibrogenesis.Mar 01, 2017

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Pubmed Data : Biofactors. 2017 Mar ;43(2):272-282. Epub 2016 Nov 1. PMID: 27801960

Article Published Date : Mar 01, 2017

Study Type : Animal Study

Additional Links

Substances : Melatonin

Diseases : Liver Cirrhosis

Pharmacological Actions : Anti-Fibrotic

Additional Keywords : Liver Regeneration

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Activation of SIRT1 by resveratrol alleviates pressure overload-induced cardiac hypertrophy.Sep 07, 2021

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Pubmed Data : Pharmacology. 2021 Sep 8:1-15. Epub 2021 Sep 8. PMID: 34518478

Article Published Date : Sep 07, 2021

Study Type : Animal Study

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Substances : Resveratrol

Diseases : Cardiac Hypertrophy

Pharmacological Actions : Anti-Fibrotic, Cardioprotective, Transforming growth factor beta (TGF-β) inhibitor

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Pubmed Data : J Food Biochem. 2021 Jun 22:e13819. Epub 2021 Jun 22. PMID: 34159624

Article Published Date : Jun 21, 2021

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Pubmed Data : SAGE Open Med. 2019 ;7:2050312119828260. Epub 2019 Feb 4. PMID: 30783524

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Vitamin C

Diseases : Fibrosis, Inflammation, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents

[+]

Asiatic acid and naringenin may represent as a novel and effective therapy for chronic kidney disease associated with fibrosis.Nov 09, 2015

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Pubmed Data : Biomed Pharmacother. 2017 May ;89:1297-1309. Epub 2017 Mar 17. PMID: 28320097

Article Published Date : Apr 30, 2017

Study Type : Animal Study

Additional Links

Substances : Gotu Kola

Diseases : Chemotherapy-Induced Toxicity: Bleomycin, Inflammation

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents

[+]

Astragaloside IV attenuates renal fibrosis through repressing epithelial-to-mesenchymal transition.Dec 31, 2018

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Pubmed Data : J Ethnopharmacol. 2019 Nov 15:112404. Epub 2019 Nov 15. PMID: 31739105

Article Published Date : Nov 14, 2019

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Astragaloside

Diseases : Cardiovascular Diseases, Myocardial Fibrosis

Pharmacological Actions : Anti-Fibrotic, Cardioprotective, MicroRNA modulator

[+]

Astragaloside IV inhibits excessive mesangial cell proliferation and renal fibrosis caused by diabetic nephropathy.Sep 30, 2019

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Pubmed Data : PLoS One. 2018 ;13(11):e0205535. Epub 2018 Nov 5. PMID: 30395570

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Pubmed Data : J Agric Food Chem. 2019 Sep 4 ;67(35):9789-9795. Epub 2019 Aug 19. PMID: 31373816

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Carvacrol suppresses the progression of liver fibrosis.Jan 31, 2019

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Pubmed Data : Immunopharmacol Immunotoxicol. 2019 Feb ;41(1):163-171. Epub 2019 Feb 1. PMID: 30706740

Article Published Date : Jan 31, 2019

Study Type : Animal Study

Additional Links

Substances : Carvacrol

Diseases : Chemically-Induced Liver Damage, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

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Celastrol exerts anti-inflammatory effect in liver fibrosis.Nov 18, 2019

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Chrysin ameliorates cyclosporine-A-induced renal fibrosis.Sep 22, 2021

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Pubmed Data : Int J Mol Sci. 2021 Sep 23 ;22(19). Epub 2021 Sep 23. PMID: 34638597

Article Published Date : Sep 22, 2021

Study Type : Animal Study

Additional Links

Substances : Chrysin

Diseases : Kidney Fibrosis

Pharmacological Actions : Anti-Fibrotic, Renoprotective

[+]

Chrysin inhibits advanced glycation end products-induced kidney fibrosis.Jul 08, 2018

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Curcumin inhibits liver fibrosis. Jan 01, 2002

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Pubmed Data : J Pharm Pharmacol. 2002 Jan;54(1):119-26. PMID: 11829122

Article Published Date : Jan 01, 2002

Study Type : Animal Study

Additional Links

Substances : Curcumin

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic

[+]

Curcumin is a potent antifibrotic agent and a promising treatment for diabetic nephropathy.Dec 31, 2016

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Pubmed Data : Cell Physiol Biochem. 2016 ;40(6):1422-1432. Epub 2016 Dec 20. PMID: 27997902

Article Published Date : Dec 31, 2015

Study Type : Animal Study

Additional Links

Substances : Flavonoids

Diseases : Liver Cirrhosis, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

[+]

Dietary tetrahydrocurcumin reduces renal fibrosis and cardiac hypertrophy.Dec 31, 2017

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Pubmed Data : Biochem Cell Biol. 2017 06 ;95(3):400-414. Epub 2016 Nov 21. PMID: 28177765

Article Published Date : Dec 31, 2016

Study Type : Animal Study

Additional Links

Substances : Diosmin

Diseases : Liver Cirrhosis, Radiation Induced Illness

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants

[+]

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Pubmed Data : Nutrients. 2021 May 30 ;13(6). Epub 2021 May 30. PMID: 34070845

Article Published Date : May 29, 2021

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Rice Bran

Diseases : Fibrosis

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Gastroprotective

[+]

Ferulic acid combined with astragaloside IV reduced the degree of pulmonary fibrosis.Dec 31, 2020

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Pubmed Data : Front Pharmacol. 2020 ;11:585163. Epub 2020 Nov 30. PMID: 33328989

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Pubmed Data : Eur J Pharmacol. 2015 Sep 5 ;762:102-11. Epub 2015 May 22. PMID: 26004525

Article Published Date : Sep 04, 2015

Study Type : Animal Study

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Substances : Geraniol

Diseases : Atherosclerosis, Fibrosis, Oxidative Stress

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, NF-kappaB Inhibitor

[+]

Ginger extract protects the heart against inflammation and fibrosis in diabetes.Sep 01, 2020

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Pubmed Data : Can J Diabetes. 2020 Sep 2. Epub 2020 Sep 2. PMID: 33162372

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Pubmed Data : Food Funct. 2021 Oct 22. Epub 2021 Oct 22. PMID: 34676843

Article Published Date : Oct 21, 2021

Study Type : Animal Study

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Substances : Piceatannol

Diseases : Chemically-Induced Liver Damage, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

[+]

Hepatoprotective effect of ultrasonicated ginseng berry extract on a rat mild bile duct ligation model.Sep 30, 2019

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Pubmed Data : J Ginseng Res. 2019 Oct ;43(4):606-617. Epub 2018 Aug 10. PMID: 31695567

Article Published Date : Sep 30, 2019

Study Type : Animal Study

Additional Links

Substances : Ginseng, Ginsenosides

Diseases : Liver Failure: Acute, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

Additional Keywords : Plant Extracts

[+]

High-fat diet-induced metabolic syndrome and oxidative stress in obese rats are ameliorated by yogurt supplementation.Dec 26, 2019

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Pubmed Data : Carbohydr Polym. 2021 Dec 1 ;273:118567. Epub 2021 Aug 19. PMID: 34560978

Article Published Date : Nov 30, 2021

Study Type : Animal Study

Additional Links

Substances : Fucoidan

Diseases : Pulmonary Fibrosis

Pharmacological Actions : Anti-Fibrotic, Interleukin-6 Downregulation, Transforming growth factor beta (TGF-β) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Low molecular weight fucoidan can inhibit the fibrosis of diabetic kidneys by regulating the kidney lipid metabolism.Dec 31, 2020

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Pubmed Data : Pathophysiology. 2017 Feb 12. Epub 2017 Feb 12. PMID: 28285737

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Pubmed Data : J Agric Food Chem. 2010 Nov 24 ;58(22):11653-61. Epub 2010 Oct 19. PMID: 20958047

Article Published Date : Nov 23, 2010

Study Type : Animal Study, In Vitro Study

Additional Links

Substances : Luteolin

Diseases : Fibrosis

Pharmacological Actions : Anti-Fibrotic, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Lycopene corrects metabolic syndrome and liver injury induced by high fat diet.Jul 05, 2021

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Pubmed Data : Biomed Pharmacother. 2021 Jul 6 ;141:111831. Epub 2021 Jul 6. PMID: 34237596

Article Published Date : Jul 05, 2021

Study Type : Animal Study

Additional Links

Substances : Lycopene

Diseases : High Fat Diet, Obesity

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants

Additional Keywords : Anti-Obesity Agents

[+]

Magnolol attenuates concanavalin A-induced hepatic fibrosis.May 31, 2017

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Pubmed Data : J Chin Med Assoc. 2017 Apr ;80(4):212-221. Epub 2017 Mar 6. PMID: 28268174

Article Published Date : Mar 31, 2017

Study Type : Animal Study

Additional Links

Substances : Fermented Foods and Beverages, Noni

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Antioxidants, Hepatoprotective, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor

[+]

Neferine may have antifibrogenic effects in diabetes-related cardiac fibrosis.Sep 19, 2016

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Pubmed Data : Oncotarget. 2016 Sep 20 ;7(38):61703-61715. PMID: 27533252

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Pubmed Data : Mol Immunol. 2019 08 ;112:247-255. Epub 2019 Jun 12. PMID: 31202101

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Neem

Diseases : Kidney Fibrosis

Pharmacological Actions : Anti-Fibrotic, Antioxidants, Renoprotective, Transforming growth factor beta (TGF-β) inhibitor

[+]

Nobiletin alleviates ferroptosis-associated renal injury, inflammation, and fibrosis.Mar 02, 2022

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Omega-3 polyunsaturated fatty acids reduces liver ﬁbrosis and promotes liver regeneration.Oct 31, 2019

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Pubmed Data : Eur Rev Med Pharmacol Sci. 2019 Nov ;23(22):10151-10160. PMID: 31799687

Article Published Date : Oct 31, 2019

Study Type : Animal Study

Additional Links

Substances : Omega-3 Fatty Acids, Polyunsaturated Fatty Acids (PUFAs)

Diseases : Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Hepatoprotective

Additional Keywords : Liver Regeneration

[+]

Oral flavonoid fisetin treatment protects against prolonged high-fat-diet-induced cardiac dysfunction.Nov 24, 2019

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Pubmed Data : J Nutr Biochem. 2019 Nov 25 ;77:108253. Epub 2019 Nov 25. PMID: 31835147

Article Published Date : Nov 24, 2019

Study Type : Animal Study

Additional Links

Substances : Fisetin

Diseases : Cardiovascular Diseases, High Fat Diet

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Cardioprotective

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Efficacy of lycopene in the treatment of oral submucous fibrosis.Jan 11, 2020

Evaluation of astragaloside IV in hepatic fibrosis: A meta-analysis. Apr 01, 2021

Tanshinone IIA can effectively improve liver fibrosis and liver function.Dec 31, 2018

This study determines the positive efficacy of vitamin D supplementation for chronic liver disease.Apr 30, 2020

Apigenin could be an attractive therapeutic potential for the treatment of renal fibrosis.Mar 20, 2020

Association between serum vitamin D level and immune imbalance in advanced schistosomiasis patients with liver fibrosis.Feb 03, 2021

Black turmeric and Aloe vera in the management of oral submucous fibrosis.Nov 30, 2021

Curcumin gel and Aloe Vera gel are effective in improving oral submucous fibrosis symptoms.Jan 31, 2021

Evaluation of efficacy of curcumin along with lycopene and piperine in the management of oral submucous fibrosis.Jun 30, 2019

Flaxseed supplementation plus lifestyle modification is more effective than lifestyle modification alone for NAFLD management.May 31, 2016

Galectin-3 inhibition with modified citrus pectin in hypertension. Dec 31, 2020

Korean Red Ginseng could be used as a complementary therapy for chronic hepatitis B.Nov 30, 2016

NAC could ameliorate COPD-induced pulmonary fibrosis by promoting immune response.Jan 02, 2021

Protective effects of propolis on hepatic steatosis and fibrosis among patients with nonalcoholic fatty liver disease.Feb 28, 2021

Pycnogenol®-Centellicum® supplementation improves lung fibrosis and Post-Covid-19 lung healing.Jun 27, 2021

Silymarin may reduce liver fibrosis.Apr 14, 2017

There was less fibrosis in elderly subjects supplemented with selenium and coenzyme Q10.Dec 07, 2017

Treatment with lycopene led to improvement in the symptoms of oral submucous fibrosis in the present study.Jul 10, 2020

Zinc administration and improved serum markers of hepatic fibrosis in patients with autoimmune hepatitis.Jun 01, 2021

Astaxanthin may be useful as a preventive/therapeutic agent for cardiac dysfunction and myocardial fibrosis.Mar 11, 2017

Baicalein represses TGF-β1-induced fibroblast differentiation through the inhibition of miR-21.Jan 01, 2018

Chebulagic acid and Chebulinic acid inhibit TGF-β1 induced fibrotic changes in the chorio-retinal endothelial cells by inhibiting ERK phosphorylation.Jan 01, 2019

Cinnamaldehyde may be able to slow down the progression of cardiac fibrosis.Mar 20, 2017

Methyl ferulic acid attenuates liver fibrosis and hepatic stellate cell activation through the TGF-β1/Smad and NOX4/ROS pathways.Feb 01, 2019

Phlorotannins should be considered a promising candidate for use in the prevention of vocal fold fibrosis.Jan 11, 2020

Photobiomodulation therapy enhances the anti-fibrotic activity of adipose-derived mesenchymal stem cells.Feb 01, 2019

Prunella vulgaris attenuates diabetic renal injury.Mar 29, 2017

Puerarin attenuates the endothelial-mesenchymal transition induced by oxidative stress in human coronary artery endothelial cells.Nov 04, 2020

Schisanhenol may be a potential anti-liver fibrosis drug.Mar 19, 2020

The antifibrotic effect of quercetin can be enhanced by adding methyl group on functionally important position.Dec 01, 2019

Icariin attenuates renal fibrosis in vivo and in vitro by inhibiting the Notch2/Hes-1 pathway.Apr 14, 2022

Successful treatment with hydrogen rich water in a case of chronic graft-versus-host-disease.Jun 30, 2016

Emodin promotes fibroblast apoptosis and prevents epidural fibrosis through PERK pathway in rats.Oct 09, 2019

Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.Jun 10, 2020

Δ9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation.Nov 29, 2020

6-Gingerol, a functional polyphenol of ginger, reduces pulmonary fibrosis by activating Sirtuin1.Dec 31, 2021

A multi-herbal product called Protandim prevents fibrosis and capillary loss and preserves right ventricular function in rats.Nov 17, 2009

A potential anti-liver fibrosis mechanism of curcumol may be associated with the inhibition of NLRP3 inflammasomes.Jul 27, 2021

A. vera supplementation protects against development of cardiac inflammation, fibrosis, and oxidative stress in isoprenaline-administered rats.Aug 31, 2019

Abrogation of the lipid signaling pathway by the indole reveals novel molecular pathways that may account for the protective effect of melatonin in liver fibrogenesis.Mar 01, 2017

Activation of SIRT1 by resveratrol alleviates pressure overload-induced cardiac hypertrophy.Sep 07, 2021

Active components from Sea Buckthorn regulate hepatic stellate cell activation and liver fibrogenesis.Nov 20, 2018

Active vitamin D impedes the progression of non-alcoholic fatty liver disease.Dec 02, 2019

Administration of thymoquinone reduced renal fibrosis and permeability and improved oxidative stress status.Nov 30, 2017

Allicin has the potential to help in the treatment of diabetic nephropathy.Nov 14, 2020

Allyl isothiocyanate reduces liver fibrosis by regulating Kupffer cell activation.Jun 05, 2018

Aloin alleviates pathological cardiac hypertrophy via modulation of the oxidative and fibrotic response.Dec 31, 2021

Ameliorating effects of white mulberry on iron-overload-induced oxidative stress and liver fibrosis.Aug 27, 2021

Amygdalin alleviates renal injury by suppressing inflammation, oxidative stress and fibrosis in streptozotocin-induced diabetes.Jan 14, 2021

Amygdalin improves microcirculatory disturbance and attenuates pancreatic fibrosis.Nov 08, 2017

Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells.Dec 31, 2020

Andrographolide prevents high glucose-induced renal tubular cell damage.Jul 08, 2021

ANG II-AT1 receptor pathway is involved in the anti-fibrotic effect of beta-elemene.Mar 31, 2009

Anti-fibrosis activity of quercetin attenuates rabbit tracheal stenosis via the TGF-β/AKT/mTOR signaling pathway.Mar 12, 2020

Anti-fibrotic actions of roselle extract in rat model of myocardial infarction.Aug 19, 2018

Anti-fibrotic effects of curcumin and some of its analogues in the heart.Sep 10, 2019

Anti-inflammatory activity of ginger modulates macrophage activation against the inflammatory pathway of monosodium glutamat.Jun 21, 2021

Anti-oxidant, anti-inflammatory and anti-fibrosis effects of ganoderic acid A on carbon tetrachloride induced nephrotoxicity.Jul 31, 2021

Antifibrotic activity of hesperidin against dimethylnitrosamine-induced liver fibrosis in rats.May 31, 2014

Antifibrotic effects of crocin on thioacetamide-induced liver fibrosis in mice.Apr 30, 2018

Antifibrotic effects of gallic acid on hepatic stellate cells.Dec 31, 2018

Antioxidant and anti-inflammatory activities of berberine attenuate hepatic fibrosis.Aug 20, 2018

Antioxidant properties of red raspberry extract alleviate hepatic fibrosis.Oct 05, 2021

Antioxidant, anti-inflammatory and anti-fibrotic effects of Boswellia serrate gum resin in CCl4-induced hepatotoxicityJan 31, 2020

Antioxidant, antiapoptotic, and antifibrotic effects of the combination of liposomal resveratrol and carvedilol against doxorubicin-induced cardiomyopathy.Mar 14, 2020

Antioxidants vitamin E and C attenuate hepatic fibrosis in biliary-obstructed rats.Nov 13, 2006

Apigenin ameliorates hyperuricemic nephropathy.May 22, 2021

Apigenin inhibits isoproterenol-induced myocardial fibrosis.Mar 10, 2022

Arctigenin could protect the kidney from unilateral ureteral obstruction induced injury and fibrogenesis.Jun 30, 2017

Artesunate alleviates liver fibrosis by regulating ferroptosis signaling pathway.Dec 31, 2018

Ascorbic acid attenuated the inflammatory response and fibrosis in the lungs of rats treated with lipopolysaccharide.Dec 31, 2018

Asiatic acid and naringenin may represent as a novel and effective therapy for chronic kidney disease associated with fibrosis.Nov 09, 2015

Anti-Fibrotic

View the Evidence:
628 Abstracts with Anti-Fibrotic Research